CN207114557U

CN207114557U - A kind of automatic lmunoassays analyzer

Info

Publication number: CN207114557U
Application number: CN201720108136.3U
Authority: CN
Inventors: 王东元; 武通园; 汪德禄
Original assignee: Shenzhen City Live Near Diagnosis Instrument Co Ltd Waterbed
Current assignee: Shenzhen City Live Near Diagnosis Instrument Co Ltd Waterbed
Priority date: 2017-02-05
Filing date: 2017-02-05
Publication date: 2018-03-16
Anticipated expiration: 2027-02-05

Abstract

The application is related to a kind of automatic lmunoassays analyzer, including sampling device（1）, reagent card conveying device（2）, feed mechanism（3）, incubating device（4）, puncture sampling assemble（5）, cleaning assembly（6）, device for discharging（7）, detection means（8）, assembly of the plunger pump（9）, bellows pumping element（10）, above-mentioned module coupled system control module combines, and each device cooperates, the automatic purpose for carrying out immune quantitative analysis is realized jointly, quantitative analysis can be carried out to a variety of samples, improve detection efficiency, and requirement is reduced to the professional standards of tester.

Description

A kind of automatic lmunoassays analyzer

Technical field

A kind of automatic lmunoassays analyzer is the utility model is related to, belongs to the immunoassays such as the fluorescence or collaurum detection head of a bed Diagnostic field.

Background technology

Full-automatic quantitative immunity analysis instrument, the full-automatic fluorescence immunity analyzers for using rotating disk mechanism especially more, just like Lower deficiency：

1) it can only uniformly be analyzed, be drawn by equal incubation time for incubation time sample different in size, analyzer It is low to play inconvenient for operation and efficiency；

2) reagent that rotating disk mechanism is placed, interruption are transported to incubation mechanism, and stand-by period length is inefficient, such as patent application CN201410836485.8 discloses a kind of full-automatic fluorescence coulometric analysis device and implementation method, and it reacts disk module 4 to turn Disk mode, not only volume is big, and reacts stand-by period length；Patent application CN201510289808.0 discloses a kind of three-dimensional fixed Position rotating disc type entry dry type fluorescence detector, test card is equally placed in test card carrier by it, uses entering for rotating disk The problem of row is tested, and the spacing existed between reagent card is big, and reaction efficiency is inadequate, when the carousel mode is set, it is between neck Radial setting, it is larger to take volume.

3) the general usual volume of fluorescent quantitative detector is larger in the prior art, and it is inconvenient to carry, and is not easy to examine immediately Test, limit it and having inconvenient traffic, the development of under-developed area.

4), it is necessary to add reagent manually when carrying out quantitative fluorescence analysis in the prior art, operating process complexity, for operation The level requirement of person is higher, meanwhile, condition is harsh, easy misoperation, causes result incorrect, meanwhile, exist in the prior art When being detected to reagent card, mobile reagent card is needed in itself, easily cause the precise decreasing of testing result.

Combination and marker material cost due to antigen-antibody is higher, it is impossible to large area is equally made with chemical reagent and is shown Color, and background has the impurity such as water, blood, marker material to cause to permeate the uneven difficulty and precision for adding detection, how Keep the volume of POCT products small, the stability detected and sensitivity are improved while easy to carry and improves efficiency, is this Technical field urgent problem to be solved.

The content of the invention

To achieve the above object, can be according to incubating in existing Full-automatic quantitative immunity analysis instrument structure in the utility model Educate that time length intelligence is full-automatic successively to realize detection, when overcoming existing Full-automatic quantitative immunity analysis instrument comprehensive detection due to Incubation time difference such as needs to wait at the drawbacks of that efficiency is low.

At least three kinds of 10 kinds of pattern detections can once be loaded to begin a project, can accurately control the reaction time.Since sample-adding Terminate to detection, the reaction time is consistent, and sample-adding precision is high, and sample-adding progress can be according to setting item by system prompt.In addition, sample and Detection project with independent assortment, according to sample needs, can carry out the independent assortment of disparity items and different samples, improve Detection efficiency.

The utility model purpose is to provide a kind of quick accurate detection patient blood (whole blood or composition blood) and other samples In cause of disease mark, it is easy to operate efficiently real for the diagnosis of the common acute disease of various diseases especially emergency treatment and severe Existing full-automatic immune quantitative detection means.

To solve above-mentioned technical problem：The application proposes a kind of automatic lmunoassays analyzer, including sampling assemble (5), clear Component (6), incubating device (4) and detection means (8) are washed, the detection means (8) is located above the incubating device (4), institute Stating incubating device (4) includes line slideway 407, is incubated monitor station 409, and at least two are provided with the incubation monitor station 409 Parallel reagent neck, the incubation monitor station 409 can move linearly along the line slideway 407 or so；The detection means (8) line slideway 806, detector 804 are included, the detector 804 of the detection means (8) is along before and after the line slideway 806 Rectilinear movement；The line slideway 407 is mutually perpendicular to the line slideway 806；The detection means (8) is to being incubated what is completed Reagent card is detected.

The reagent card in the incubating device (4) can be kept fixed to be detected to it, the cleaning assembly (6) Agitating device to mix cup in liquid fully mixed, and can using cleaning device to taking in sampling assemble (5) Sample pin is cleaned.

Described automatic lmunoassays analyzer, wherein, the sampling assemble (5) can according to the automatic direct sample of program setting, Or sampled again after automatic puncturing.

Described automatic lmunoassays analyzer, wherein, the detection means (8) is located at straight line with the sampling device (1) Both sides of guide rail 407 or positioned at the same side of line slideway 407.

Described automatic lmunoassays analyzer, wherein, the incubating device (4) is movable incubating device, in addition to temperature control Electronic module 410, the temperature control electronic module 410, can be with the incubation monitor stations positioned at the bottom surface of the incubation monitor station 409 409 movements, for controlling the temperature of the incubation monitor station 409.

Described automatic lmunoassays analyzer, wherein, the incubating device (4) also includes motor 401, synchronous belt 402nd, near-end inductor 403, sensing chip 404, bearing 405, distal end inductor 406, sliding block 408, the near-end inductor 403, Distal end inductor 406 is arranged at is located at the line slideway 407 in the both ends of the line slideway 407, the synchronous belt 402 Side be arranged in parallel, the incubation monitor station 409 is arranged on the line slideway 407, and the motor 401 drives institute Synchronous belt 402 is stated to act.

Described automatic lmunoassays analyzer, wherein, the sampling device (1) includes rack for test tube 101, bearing 104, initial Level sensor 105, motor 107, terminal inductor 108 and the multiple samples 102 being positioned in the rack for test tube 101, sample Or buffer solution 103, the bearing 104 places the linear platform of plane of the rack for test tube 101, in the entry position of linear platform Initial sensor 105 is set, baffle plate is set in the end of linear platform, and sets terminal inductor 108, institute in the lower end of baffle plate The side that motor 107 is arranged at the linear platform is stated, it connects and acted with moving gear 106, and the gear 106 is arranged at institute The bottom of linear platform is stated, gear 106 and the tooth-like part of rack for test tube bottom are intermeshed.

Described automatic lmunoassays analyzer, wherein, the detection means (8) includes replaceable detector, the inspection Gauge head includes at least one fluoroscopic examination head, collaurum detector.

The detection means (8) also include motor 801, screw mandrel 802, screw mandrel mother set 803, sliding block 805, sensing chip 807, Inductor 808, motor mounting plate 809, bearing 810, the screw mandrel 802 control the detector under the driving of motor 801 804 move along the tandem of line slideway 806, and to be detected to the reagent card being incubated, the inductor 808 is used to feel The positional information of detector is surveyed, the detector 804 is higher than the incubation monitor station 409.

Described automatic lmunoassays analyzer, wherein, the cleaning assembly (6) includes mixing cup 602, Washing cup 610, institute State and mix that cup 602, Washing cup 610 are placed side by side, it is described to mix the several samples that 602 pairs of the cup sampling assemble (5) is taken out and enter Row mixes, and the Washing cup 610 all cleans afterwards to the sampling assemble (5) per sub-sampling.

Described automatic lmunoassays analyzer, wherein, the cleaning assembly (6) also includes cleaning fluid import 601, supporting slice 603rd, waste liquid outlet 604, magnetic couplings mixing component 605, motor 606, support 607, waste liquid outlet 608, cleaning fluid import 609, the supporting slice 603 is used to fix the cleaning fluid import 601, and the waste liquid outlet 604 is positioned at the mixing cup 602 Bottom, the cleaning fluid import 609 are arranged at the side of Washing cup 610, and the waste liquid outlet 608 is arranged at the Washing cup 610 bottom, magnetic couplings mixing component 605 are stirred mixing to mixing cup 602.

Described automatic lmunoassays analyzer, wherein, the sampling assemble (5) includes portal frame 518, punctures sampling probe 513rd, part, horizontal balance part are moved up and down, the horizontal balance part drives puncture sampling probe 513 movable, described Up and down action part drives puncture sampling probe 513 to move up and down and is sampled, and the horizontal balance part is located at the portal frame On 518 cross bar.

Described automatic lmunoassays analyzer, wherein, the up and down action part includes moving up and down motor 501, ball Screw mandrel 510, sliding block 511, sensing chip 512；The horizontal balance part includes moving horizontally motor 502, synchronous belt 503, straight Line guide rail 504, inductor 505, bevel gear set 506, splined shaft 507, sensing chip 508, inductor 509；In the up and down action The bottom of part sets cleaning chamber 514, rinse liquid outlet 515, cleaning fluid import 516, and the sampling probe 513 is carried out clearly Wash, code reader 517 is set in the montant bottom of the portal frame 518.

Described automatic lmunoassays analyzer, wherein, in addition to reagent card conveying device (2) and feeding structure (3), it is described Multiple reagent cards are moved in parallel the feeding structure (3) by reagent card conveying device (2), and the feeding structure (3) successively will Each of the multiple reagent card is pushed to the correspondence position of the incubation monitor station 409.

Described automatic lmunoassays analyzer, wherein, the reagent card conveying device (2) includes motor 201, synchronous belt 202nd, drive pulley wheel assembly 203, belt 204, cover plate 205, support 206, code reader 207, the width of the belt 204 with The length of reagent card matches, and the cover plate 205 is covered on the belt 204 with the belt 204 holding certain intervals Portion, the certain intervals are more than or equal to the thickness of reagent card, less than the width of reagent card, read to state yard device 207 positioned at described The side of the porch of cover plate 205, and it is higher than the cover plate 205, the information for reading reagent card.

Described automatic lmunoassays analyzer, wherein, the feeding structure (3) includes motor 301, synchronous belt 302, slided Block 303, guide rail 304, pusher pole 305, sensing chip 306, inductor 307, the pusher pole 305 are moved along guide rail 304 It is dynamic, the correspondence position of the incubation monitor station 409, the sensing chip 306 and pusher pole 305 are snapped into for pushing reagent Put and be consistent, the position of sensing chip 306 is detected to judge the position of pusher pole 305 by inductor 307.

Described automatic lmunoassays analyzer, wherein, in addition to device for discharging (7), the device for discharging (7) include bearing 701st, motor 702, screw mandrel 703, nut sleeve 704, discharge arm 705, near-end inductor 706, sensing chip 707, distal end inductor 708th, spent reagent disposable box 709, the screw mandrel 703 are driven the discharge arm 705, and the discharge arm 705 promotes spent reagent to institute State in spent reagent disposable box 709, described unload is sensed by the near-end inductor 706, sensing chip 707, distal end inductor 708 Expect the positional information of bar 705, the sensing chip 707 is arranged on the discharge arm 705, and both holding positions are consistent.

Described automatic lmunoassays analyzer, wherein, in addition to assembly of the plunger pump (9), bellows pumping element (10), the post Filling in pump group part (9) includes bearing 901, motor 902, plunger pump 903, pump inlet 904, pump discharge 905, magnetic valve 906；It is described Bellows pumping element (10) includes bearing 1001, barrier film waste drains pump 1002, barrier film liquid feeding pump 1003, magnetic valve 1004, magnetic valve 1005, according to setting program, system control assembly of the plunger pump (9), bellows pumping element (10) and respective line, puncturing sampling probe can be Sample, buffer solution, cleaning fluid are quantitatively drawn or injected between each position, can also be sucked and be gone out Liquid Residue in pin after air again Body, and waste liquid is injected waste liquid recovery apparatus.

A kind of Full-automatic quantitative immunity analysis instrument of the present utility model has the following advantages that：

1) under the control of system control module, sampling device, incubating device, sampler, data acquisition device, reagent Card device and system control module combine, and each device cooperates, and realize to carry out being immunized automatically jointly and determine Measure the purpose of analysis.

2) this instrument puncture sampling assemble can be according to being sampled again after the automatic direct sample of program setting or automatic puncturing.

3) only project to be measured need to be set in system, instrument is sequentially placed required reagent by sample prompting, is not required to shake It is even, uncap, the operation such as pre-dilution, you can start automatic detection analysis and output result.

4) by using cleaning device, the use of medical disposable material is eliminated, operating cost reduces, green；Pass through The agitating device mixed in the motor driven mixing cup of cup bottom setting carries out fully mixing etc. to the liquid mixed in cup.Each portion Part cooperates under control system control, co-ordination, realizes instrument intelligent prompt and false alarm, further increases this The automaticity and performance of analyzer.

5) reagent card is fixed, and core detector can be detected along guide rail rectilinear movement in detection means, compared with it He can reach higher accuracy of detection by mobile reagent card, by mobile detector, keeps the stabilization of reagent card, reduces reagent card and move It is dynamic to cause the changes such as reaction environment, temperature to cause reaction result error occur.

6) a kind of quantitative immunological detection method of the present utility model, using above-mentioned automatic lmunoassays analyzer, to a variety of Sample realizes existing automatic intelligent instrumental quantitative analysis, expands detection range, improves detection efficiency, and to tester Professional standards reduce requirement.

7) in the utility model by incubation reaction platform be arranged to rectilinear movement mode, structure relative to prior art circle The mode of disk is simpler, meanwhile, set between neck by adjacent parallel mode, middle disk is into radial compared with the prior art Set the obvious volume of mode of neck much smaller, analyzer of the present utility model is easy to carry, the application passes through multiple structures Be skillfully constructed, make accuracy of detection higher, using effect protrude.

8) due to the raising of accuracy of detection, using the reduction of volume, the cost of equipment is greatly reduced.

Brief description of the drawings

Fig. 1 is automatic lmunoassays analyzer internal structure schematic diagram；

Fig. 2 is sampling device structural representation；

Fig. 3 is reagent card transport conveyor constructions schematic diagram；

Fig. 4 is feeding mechanism schematic diagram；

Fig. 5 is movable incubating device structural representation；

Fig. 6 is puncture sampling assemble structural representation；

Fig. 7 cleans part structural representation to mix；

Fig. 8 is device for discharging structural representation；

Fig. 9 is structure of the detecting device schematic diagram；

Figure 10 is assembly of the plunger pump structural representation；

Figure 11 is bellows pumping element structural representation.

Embodiment

The application is described in further detail below in conjunction with the accompanying drawings, it is necessary to it is pointed out here that, implement in detail below Mode is served only for that the application is further detailed, it is impossible to the limitation to the application protection domain is interpreted as, the field Technical staff can make some nonessential modifications and adaptations to the application according to above-mentioned application content.

Embodiment one：

As shown in figure 1, propose a kind of automatic lmunoassays analyzer, including the conveying of sampling device (1), reagent card for the application Device (2), feed mechanism (3), incubating device (4), puncture sampling assemble (5), cleaning assembly (6), device for discharging (7), detection Device (8), assembly of the plunger pump (9), bellows pumping element (10).

It is illustrated in figure 2 sampling device structural representation, the sampling device (1) includes rack for test tube 101, bearing 104, just Beginning level sensor 105, motor 107, terminal inductor 108 and the multiple samples 102 being positioned in the rack for test tube 101, examination Sample or buffer solution 103, the bearing 104 places the linear platform of plane of the rack for test tube 101, in the entrance position of linear platform Initial sensor 105 is installed, baffle plate is set in the end of linear platform, and terminal inductor 108 is set in the lower end of baffle plate, The motor 107 is arranged at the side of the linear platform, and it is connected and acted with moving gear 106, and the gear 106 is arranged at The bottom of the linear platform, gear 106 and the tooth-like part of rack for test tube bottom are intermeshed.

Reagent card transport conveyor constructions schematic diagram is illustrated in figure 3, is illustrated in figure 4 feeding structure schematic diagram, wherein, also Including reagent card conveying device (2) and feeding structure (3), the reagent card conveying device (2) moves in parallel multiple reagent cards To the feeding structure (3), each by the multiple reagent card is pushed to the incubation inspection to the feeding structure (3) successively The correspondence position of scaffold tower 409.

Wherein, the reagent card conveying device (2) include motor 201, synchronous belt 202, drive pulley wheel assembly 203, Belt 204, cover plate 205, support 206, code reader 207；The code reader 207 is arranged at the one of reagent card conveying device (2) Side, and it is higher than the cover plate 205.The feeding structure (3) include motor 301, synchronous belt 302, sliding block 303, guide rail 304, Pusher pole 305, sensing chip 306, inductor 307, the pusher pole 305 are moved along guide rail 304, arrived for pushing reagent Certain position, the sensing chip 306 are consistent with the position of pusher pole 305, and sensing chip 306 is detected by inductor 307 Position to judge the position of pusher pole 305.

The motor 301 is arranged on the side of guide rail 304, and guide rail 304 may be selected to be cylindrical column, and motor 301 rotates Synchronous belt 302 is driven, the synchronous belt 302 drives the pusher pole 305 to be moved along cylindrical column, inductor 307 are arranged on the end of guide rail 304, and the sliding block 303 is arranged on the lower end of pusher pole 305.

The width of the belt 204 and the length of reagent card match, and the cover plate 205 keeps one with the belt 204 Surely what is be spaced is covered in the top of belt 204, and the certain intervals are more than or equal to the thickness of reagent card, less than reagent card Width, read to state the side for the porch that yard device 207 is located at the cover plate 205, and be higher than the cover plate 205, tried for reading The information of agent card, the cover plate 205 use transparent material, and can be used for observation makes reagent card move as requested, and and can is enough anti- Dirt waterproof.

As shown in figure 5, being movable incubating device structural representation, the incubating device (4) includes line slideway 407, incubated Monitor station 409 is educated, the incubation monitor station 409 can move linearly along the line slideway 407 or so, the detection means (8) Detector 804 by being moved along the tandem of line slideway 806, the reagent card in the incubating device (4) can be kept It is fixed to be detected to it.

The incubating device (4) also includes motor 401, synchronous belt 402, near-end inductor 403, sensing chip 404, bearing 405th, distal end inductor 406, sliding block 408, temperature control electronic module 410, the near-end inductor 403, distal end inductor 406 are set It is be arranged in parallel in the both ends of the line slideway 407, the side that the synchronous belt 402 is located at the line slideway 407, institute State incubation monitor station 409 and be fixedly installed on the top of the sliding block 408, while the straight line is snapped onto by the sliding block 408 On guide rail 407, the motor 401 drives the synchronous belt 402 to act, and enables incubation monitor station 409 left along line slideway Right linear motion.The near-end inductor 403, sensing chip 404, the sensing of distal end inductor 406 are incubated the position letter of monitor station 409 Breath, the sensing chip 404 are used to identify the position on the line slideway 407 for being incubated monitor station.

It is illustrated in figure 6 and punctures sampling assemble schematic diagram, wherein, the sampling assemble (5) includes portal frame 518, punctured Sampling probe 513, part, horizontal balance part are moved up and down, the horizontal balance part, which drives, punctures the front and rear shifting of sampling probe 513 Dynamic, the up and down action part drives puncture sampling probe 513 to move up and down and is sampled, and the horizontal balance part is positioned at described On the cross bar of portal frame 518.

The up and down action part includes moving up and down motor 501, screw mandrel 510, sliding block 511, sensing chip 512；The water Flat action component include move horizontally motor 502, synchronous belt 503, line slideway 504, inductor 505, bevel gear set 506, Splined shaft 507, sensing chip 508, inductor 509；The cross bar for moving up and down motor 501 and being arranged on the portal frame 518 One end, the wherein vertical top and the position of cross bar handing-over for moving horizontally motor 502 and the portal frame 518 being set Put, the line slideway 504 be arranged in parallel with cross bar, and the inductor 505 sets the downside of line slideway 504 close to wherein one Montant position, the inductor 509 is arranged on the left side of the splined shaft 507 close to upper position, for sensing the sensing Piece 512.In the bottom of the up and down action part, cleaning chamber 514, rinse liquid outlet 515, cleaning fluid import 516 are set, it is right The sampling probe 513 is cleaned, and code reader 517 is set in the montant bottom of the portal frame 518.

Puncture sampling probe 513 end is installed on the sliding block 511, and can be in the presence of the sliding block 511 up and down Movement is punctured, and the sliding block 511 is installed on the ball screw 510, and can be in the screw mandrel 510 and synchronous belt The puncture sampling probe 513 is set to switch between sampling position, buffer solution storehouse, mixing cup and loading position in the presence of 503, it is described to wear Sampling probe 513 is pierced through the cleaning chamber 514；The code reader 517 is arranged at the lower end of the vertical bar of the portal frame 518 Portion.The sampling assemble (5) can be according to sampling again after the automatic direct sample of program setting or automatic puncturing.

It is illustrated in figure 7 and mixes cleaning assembly schematic diagram, wherein, the cleaning assembly (6) includes mixing cup 602, cleaning Cup 610, the mixing cup 602, Washing cup 610 are placed side by side, described to mix the more of 602 pairs of cup sampling assemble (5) taking-up Kind sample is mixed, and the Washing cup 610 all cleans afterwards to the sampling assemble (5) per sub-sampling.

The cleaning assembly (6) also includes cleaning fluid import 601, supporting slice 603, waste liquid outlet 604, magnetic couplings stirring Component 605, motor 606, support 607, waste liquid outlet 608, cleaning fluid import 609, the supporting slice 603 are described clear for fixing Washing lotion import 601, the waste liquid outlet 604 are arranged at clearly positioned at the bottom of the mixing cup 602, the cleaning fluid import 609 The side of cup 610 is washed, the waste liquid outlet 608 is arranged at the bottom of the Washing cup 610, and magnetic couplings mixing component 605 is right Mix cup 605 and be stirred mixing.

The agitating device of the cleaning assembly (6) is fully mixed to mixing the liquid in cup, and can use cleaning Device cleans to mixing cup, after the puncture sampling assemble (5) can be according to the automatic direct sample of program setting or automatic puncturing Sample again

Device for discharging schematic diagram is illustrated in figure 8, wherein, in addition to device for discharging (7), the device for discharging (7) include Bearing 701, motor 702, ball screw 703, ball nut set 704, discharge arm 705, near-end inductor 706, sensing chip 707, Distal end inductor 708, spent reagent disposable box 709.The ball screw 703 is driven the discharge arm 705, the discharge arm 705 Spent reagent is promoted to pass through the near-end inductor 706, sensing chip 707, distal end inductor into the spent reagent disposable box 709 The positional information of the 708 sensing discharge arms 705, the sensing chip 707 are arranged on the discharge arm 705, both holding positions Put consistent.The detection means (8) is located at the both sides of line slideway 407 or positioned at line slideway 407 with the sampling device (1) The same side.

Structure of the detecting device schematic diagram is illustrated in figure 9, wherein, the detection means (8) also includes motor 801, screw mandrel 802nd, screw mandrel mother set 803, sliding block 805, sensing chip 807, inductor 808, motor mounting plate 809, bearing 810, the screw mandrel 802 Under the driving of motor 801, the detector 804 is controlled to be moved along the tandem of line slideway 806, with to the reagent being incubated Card is detected, and the inductor 08, inductor 808 are used for the positional information for sensing detector, and the detector 804 is higher than institute State and be incubated monitor station 409.

The detector is quantitative fluorescence analysis detector, for carrying out fluoroscopic examination to reagent card.

It is as shown in Figure 10 assembly of the plunger pump schematic diagram, is as shown in figure 11 bellows pumping element schematic diagram, wherein, in addition to Assembly of the plunger pump (9), bellows pumping element (10), it is in upper and lower arrangement that the assembly of the plunger pump (9) is overall, from bottom to top successively For bearing 901, motor 902, plunger pump 903, pump inlet 904, pump discharge 905, magnetic valve 906, wherein, the bearing 901, electricity Machine 902, plunger pump 903 are fixed by elongated plates, and the magnetic valve 906 is arranged at the side position of elongated plates upper end Put；The bellows pumping element (10) include bearing 1001, barrier film waste drains pump 1002, barrier film liquid feeding pump 1003, magnetic valve 1004, Magnetic valve 1005, the barrier film waste drains pump 1002, barrier film liquid feeding pump 1003 are parallel side by side, the magnetic valve 1004, magnetic valve 1005 it is parallel side by side, be arranged on barrier film waste drains pump 1002, the top of 1003 parallel juxtaposed positions of barrier film liquid feeding pump.The plunger pump Component (9) is a kind of constant displacement pump, by corresponding magnetic valve open and close on component, puncture sampling probe calibrated shot can be achieved and go out liquid Also suction liquid can be quantified, can also suck and go out residual liquid in pin after air again, the bellows pumping element (10) is a kind of Micropump, it can be flowed out by corresponding magnetic valve open and close on component after making its intraluminal liquid pressing.According to setting program, system Assembly of the plunger pump (9), bellows pumping element (10) and respective line are controlled, puncturing sampling probe can quantitatively draw or note between each position Sample, buffer solution, cleaning fluid are projected, can also suck and go out residual liquid in pin after air again, and returns waste liquid injection waste liquid Receiving apparatus.

Embodiment two：

Detection means (8) includes detector, and the detector can be changed manually, and collaurum detection can be selected in the detector Head, for carrying out collaurum detection, other structures or part are identical with fluorescence detection device.

A kind of automatic lmunoassays analyzer of the present utility model has the following advantages that：

6) a kind of quantitative immunological detection method of the present utility model, using above-mentioned automatic lmunoassays analyzer, to a variety of Sample realizes automatic intelligent instrumental quantitative analysis, expands detection range, improves detection efficiency, and to tester's Professional standards reduce requirement.

The application includes but is not limited to specific executing agency, transmission and controlling organization, the inductive switch described in accompanying drawing, Usable chain, rack-and-pinion are such as driven, or other drivings etc., all institutes within the spirit and principles of the utility model can be used All any modification, equivalent and improvement of work etc., should be included within the scope of protection of the utility model.

Claims

A kind of 1. automatic lmunoassays analyzer, it is characterised in that：Including sampling assemble (5), cleaning assembly (6), incubating device (4) With detection means (8), the detection means (8) is located above the incubating device (4), and the incubating device (4) includes first Line slideway (407), monitor station (409) is incubated, at least two parallel reagent cards are provided with the incubation monitor station (409) Groove, the incubation monitor station (409) can move linearly along the first straight line guide rail (407) left and right；Detection means (8) bag Second straight line guide rail (806), detector (804) are included, the detector (804) of the detection means (8) is led along the second straight line Rail (806) tandem moves；The first straight line guide rail (407) is mutually perpendicular to the second straight line guide rail (806)；It is described Detection means (8) detects to being incubated the reagent card completed.
2. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：The sampling assemble (5) can set according to program Sampled again after fixed automatic direct sample or automatic puncturing.
3. automatic lmunoassays analyzer as claimed in claim 2, it is characterised in that：The detection means (8) and sampling device (1) positioned at the both sides of the first straight line guide rail (407) or positioned at the same side of first straight line guide rail (407).
4. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：The incubating device (4) is incubated to be movable Device, in addition to temperature control electronic module (410), the temperature control electronic module (410) is positioned at the bottom of the incubation monitor station (409) Face, for controlling the temperature of the incubation monitor station (409).
5. automatic lmunoassays analyzer as claimed in claim 4, it is characterised in that：The incubating device (4) also includes the 4th Motor (401), the 4th synchronous belt (402), the 4th near-end inductor (403), the 4th sensing chip (404), the 4th bearing (405), the 4th distal end inductor (406), Four-slider (408), the 4th near-end inductor (403), the 4th distal end sense Device (406) is arranged at is located at described first in the both ends of the first straight line guide rail (407), the 4th synchronous belt (402) The side of line slideway (407) be arranged in parallel, and the incubation monitor station (409) is fixedly installed on the Four-slider (408) Top, and snapped onto by the Four-slider (408) on the first straight line guide rail (407), the 4th motor (401) band Dynamic 4th synchronous belt (402) action.
6. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：Also include sampling device (1), the sample introduction Device (1) includes rack for test tube (101), the first bearing (104), initial sensor (105), the first motor (107), terminal inductor (108) and the multiple samples (102), sample or the buffer solution (103) that are positioned in the rack for test tube (101), described first Seat (104) places the linear platform of plane of the rack for test tube (101), and initial sensor is set in the entry position of linear platform (105), baffle plate is set in the end of linear platform, and terminal inductor (108), first motor are set in the lower end of baffle plate (107) side of the linear platform is arranged at, it connects and acted with moving gear (106), and the gear (106) is arranged at institute The bottom of linear platform is stated, gear (106) and the tooth-like part of rack for test tube bottom are intermeshed.
7. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：The detection means (8) includes replaceable Detector, the detector includes fluoroscopic examination head, at least one collaurum detector.
8. automatic lmunoassays analyzer as claimed in claim 7, it is characterised in that：The detection means (8) also includes the 8th Motor (801), the 8th screw mandrel (802), the 8th screw mandrel mother set (803), the 8th sliding block (805), the 8th sensing chip (807), the 8th Inductor (808), motor mounting plate (809), the 8th bearing (810), the 8th screw mandrel (802) is in the 8th motor (801) Under driving, the detector (804) is controlled to be moved along second straight line guide rail (806) tandem, with to the reagent card being incubated Detected, the 8th inductor (808) is used for the positional information for sensing detector, and the detector (804) is higher than described It is incubated monitor station (409).
9. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：The cleaning assembly (6) includes mixing cup (602), Washing cup (610), the mixing cup (602), Washing cup (610) are placed side by side, and the mixing cup (602) takes to described The several samples that sample component (5) takes out are mixed, after the Washing cup (610) is to the every sub-sampling of the sampling assemble (5) All cleaned.
10. automatic lmunoassays analyzer as claimed in claim 9, it is characterised in that：The cleaning assembly (6) also includes first Cleaning fluid import (601), supporting slice (603), the first waste liquid outlet (604), magnetic couplings mixing component (605), the 6th motor (606), support (607), the second waste liquid outlet (608), the second cleaning fluid import (609), the supporting slice (603) are used to fix The first cleaning fluid import (601), first waste liquid outlet (604) is positioned at the bottom of the mixing cup (602), and described the Two cleaning fluid imports (609) are arranged at the side of Washing cup (610), and second waste liquid outlet (608) is arranged at the cleaning The bottom of cup (610), magnetic couplings mixing component (605) are stirred mixing to mixing cup (602).
11. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：The sampling assemble (5) includes portal frame (518), puncture sampling probe (513), move up and down part, horizontal balance part, the horizontal balance part, which drives, punctures sampling Pin (513) is movable, and the up and down action part drives puncture sampling probe (513) to move up and down and is sampled, the level Action component is located on the cross bar of the portal frame (518).
12. automatic lmunoassays analyzer as claimed in claim 11, it is characterised in that：The up and down action part is included up and down Mobile motor (501), the 5th screw mandrel (510), the 5th sliding block (511), 6th sense answer piece (512)；The horizontal balance part bag Include and move horizontally motor (502), the 5th synchronous belt (503), the 3rd line slideway (504), the 4th inductor (505), cone tooth Wheel group (506), splined shaft (507), the 5th sensing chip (508), the 5th inductor (509)；Under the up and down action part End set cleaning chamber (514), the 3rd rinse liquid outlet (515), the 4th cleaning fluid import (516), to the sampling probe (513) Cleaned, code reader (517) is set in the montant bottom of the portal frame (518).
13. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：Also include reagent card conveying device (2) and Multiple reagent cards are moved in parallel the feeding structure (3) by feeding structure (3), the reagent card conveying device (2), it is described enter Each by the multiple reagent card is pushed to the correspondence position of the incubation monitor station (409) to material structure (3) successively.
14. automatic lmunoassays analyzer as claimed in claim 13, it is characterised in that：Reagent card conveying device (2) bag Include the second motor (201), the second synchronous belt (202), drive pulley wheel assembly (203), belt (204), cover plate (205), machine Seat (206), code reader (207), the width of the belt (204) and the length of reagent card match, the cover plate (205) and institute That states belt (204) holding certain intervals is covered in the belt (204) top, and the certain intervals are more than or equal to reagent card Thickness, less than the width of reagent card, read to state the side for the porch that a yard device (207) is located at the cover plate (205), and be higher than The cover plate (205), the information for reading reagent card.
15. automatic lmunoassays analyzer as claimed in claim 13, it is characterised in that：The feeding structure (3) includes the 3rd Motor (301), the 3rd synchronous belt (302), the 3rd sliding block (303), guide rail (304), pusher pole (305), the 3rd sensing chip (306), the 3rd inductor (307), the pusher pole (305) is mobile along guide rail (304), for push reagent snap into it is described The correspondence position of monitor station (409) is incubated, the 3rd sensing chip (306) is consistent with pusher pole (305) position, passed through 3rd inductor (307) detects the position of the 3rd sensing chip (306) to judge the position of pusher pole (305).
16. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：Also include device for discharging (7), it is described to unload Expect that device (7) includes the 7th bearing (701), the 7th motor (702), ball screw (703), nut sleeve (704), discharge arm (705), the 7th near-end inductor (706), the 7th sensing chip (707), the 7th distal end inductor (708), spent reagent disposable box (709), the ball screw (703) is driven the discharge arm (705), and the discharge arm (705) promotes spent reagent to be given up to described In reagent disposable box (709), pass through the 7th near-end inductor (706), the 7th sensing chip (707), the 7th distal end inductor (708) positional information of the discharge arm (705) is sensed, the 7th sensing chip (707) is arranged on the discharge arm (705) On, both holding positions are consistent.
17. automatic lmunoassays analyzer as claimed in claim 1, it is characterised in that：Also include assembly of the plunger pump (9), barrier film Pump group part (10), the assembly of the plunger pump (9) include the 9th bearing (901), the 9th motor (902), plunger pump (903), pump and entered Mouth (904), pump discharge (905), the first magnetic valve (906)；The bellows pumping element (10) includes the tenth bearing (1001), barrier film Waste drains pump (1002), barrier film liquid feeding pump (1003), second solenoid valve (1004), the 3rd magnetic valve (1005), according to setting program, it is System control assembly of the plunger pump (9), bellows pumping element (10) and respective line, puncture sampling probe can quantitatively be drawn between each position or Sample, buffer solution, cleaning fluid are injected, can also suck and go out residual liquid in pin after air again, and waste liquid is injected waste liquid Retracting device.