CN106309244B - It is a kind of containing there are many lightening compositions of fresh flower and preparation method thereof - Google Patents
It is a kind of containing there are many lightening compositions of fresh flower and preparation method thereof Download PDFInfo
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- CN106309244B CN106309244B CN201610882488.4A CN201610882488A CN106309244B CN 106309244 B CN106309244 B CN 106309244B CN 201610882488 A CN201610882488 A CN 201610882488A CN 106309244 B CN106309244 B CN 106309244B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- Animal Behavior & Ethology (AREA)
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- Birds (AREA)
- Dermatology (AREA)
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- Engineering & Computer Science (AREA)
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Abstract
The present invention provides a kind of containing there are many lightening compositions of fresh flower and preparation method thereof, the lightening compositions include each component of following mass percent: butanediol 1.0%~10.0%, xanthan gum 0.01%~0.8%, sodium lactate 1.0%~10.0%, panthenol 0.1%~5.0%, peony extract 0.1%~10.0%, safflower extract 0.1%~10.0%, Chinese herbaceous peony flower extract 0.1%~10.0%, Flos persicae extract 0.1%~10.0%, niacinamide 0.1%~2.0%, Phenoxyethanol 0.1%~0.8%, pungent glycol 0.1%~0.8%, surplus is deionized water.Provided by the invention containing there are many lightening compositions of fresh flower, not only at low cost and whitening effect is good, not only has long-acting whitening effect, but also has effects that good moisturizing, anti-inflammatory and releive.
Description
Technical field
It is the invention belongs to cosmetic technical field, in particular to a kind of containing there are many lightening compositions of fresh flower and its preparations
Method.
Background technique
" skin such as congealed fat, if face peach blossom ", this two word are usually used to describe beauty, and this beauty is also our Asians one
The target directly pursued.People increasingly pursue the pale skin of health, so that the demand of lightening compositions is more and more big.Skin
Color is mainly determined according in Skin Cell containing the quantity of melanin, size and distribution.
In conjunction with the activity problems of tyrosinase, mainly from two Study of way, first is that the damage type of tyrosinase inhibits, it can
Directly to modify the active site of tyrosinase, so that tyrosinase loses to the effect of melanocyte precursor-tyrosine；Two
It is the non-damage type inhibition of tyrosinase, by inhibiting the biosynthesis of tyrosinase or by competing with substrate tyrosine progress
It strives, to reach the formation for inhibiting melanin.Secondly the transmitting of melanin should be prevented.Some substances can inhibit melanin granule
The process shifted from melanocyte to horn cell.Finally, the metabolism of melanin should be accelerated.It is synthesized in melanin granule
Afterwards, it on the one hand can be restored, the oxidation state melanin granule of black is made to restore the reproducibility melanin granule for becoming white,
Secondly, the melanin granule being transferred in skin corium is mainly the lysosome by cell, by sending out with certain enzymes in lysosome
Raw effect, final catabolism fall, so, by the way that the substance that cell can be stimulated to generate lysosome is added, to shorten cutin metabolism
Period, to accelerate falling off for cuticula.
The whitening composition used in the market by sources divides, and can be divided into plant extract class and synthesis class, this two major classes beauty
Bai Chengfen shows respective advantage and disadvantage, plant extract class natural component safety, effect diversification, but its shortcoming is that cost is remote
It to be far more than synthesis constituents.And it is low to synthesize constituents general cost, it is cheap, preferably with the compatibility of other compositions, but
Disadvantage is relatively single, effect narrow scope in terms of effect.
Traditional plant extract class whitening composition is extracted according to water heating leaching method mostly, this method equipment is simple,
It is at low cost, easy to operate, but have the shortcomings that active constituent destruction is big, impurity content is high.
Summary of the invention
The present invention is to make up some shortcomings of the existing technology, provide it is a kind of containing there are many lightening compositions of fresh flower,
The lightening compositions are not only at low cost and whitening effect is good, not only have long-acting whitening effect, but also have and protect well
It is wet, anti-inflammatory and the effect of releive.
The present invention be reach its purpose, the technical solution adopted is as follows:
It is a kind of containing there are many lightening compositions of fresh flower, each component including following mass percent: butanediol 1.0%~
10.0%, xanthan gum 0.01%~0.8%, sodium lactate 1.0%~10.0%, panthenol 0.1%~5.0%, peony extract
0.1%~10.0%, safflower extract 0.1%~10.0%, Chinese herbaceous peony flower extract 0.1%~10.0%, Flos persicae extract
0.1%~10.0%, niacinamide 0.1%~2.0%, Phenoxyethanol 0.1%~0.8%, pungent glycol 0.1%~0.8%, surplus
For deionized water.
Preferably, the peony extract, safflower extract, Chinese herbaceous peony flower extract, Flos persicae extract are according to including such as
It is prepared by the method for lower step:
1) petal is ground into powder；
2) powder of step 1) is added into supercritical extraction reactor, carbon dioxide stream is inputted into supercritical extraction reactor
Body, carbon dioxide flow rate are 10~20kg/h, and extracting pressure is 25~30MPa, and extraction temperature is 25-35 DEG C；
3) extraction gained mixture is taken out from supercritical extraction reactor, is fed the mixture into overcritical separating still, point
Tripping power is 6~8MPa, and temperature is 35~36 DEG C；
4) separation product obtained by step 3) is added to the water by solid-liquid ratio 1: 5~15 (unit g/L), heating distillation 2~4
Hour, recycling of condensed steam obtains extract.
It is further preferred that petal is ground into partial size≤80 mesh powder in step 1).
As a kind of specific embodiment, in step 2), extraction time is 2~4 hours.
As a kind of specific embodiment, in step 3), disengaging time is 1~3 hour.
As a kind of specific embodiment, in step 4), using straight fire heating distillation.
Second aspect of the present invention provides a kind of method for preparing lightening compositions as described above, includes the following steps:
1) xanthan gum is soaked with butanediol, be added water phase pot in, under stirring, sequentially add sodium lactate, panthenol,
Deionized water is warming up to 80 DEG C, heat preservation, until being completely dissolved；
2) mixture obtained by step 1) is passed through in vacuum suck emulsion pot, homogeneous；
3) 40~50 DEG C are cooled to, niacinamide is added in emulsion pot, is stirred and evenly mixed；
4) peony extract, safflower extract, Chinese herbaceous peony flower extract and Flos persicae extract are added in emulsion pot, stirring
It mixes；
5) 40 DEG C are cooled to hereinafter, stirring and evenly mixing in remaining components addition emulsion pot.
Technical solution provided by the invention has the following beneficial effects:
1, lightening compositions provided by the invention, the method preparation that several fresh flower extracts therein are optimized using the present invention
And obtain, the extract of a large amount of high-purity can be rapidly extracted under the premise of not destroying fresh flower active skull cap components, no
The problem of only yield is high, and impurity is few, and extraction process is not needed using any solvent, prevents dissolvent residual, keeps extracting
The natural characteristic of object, effective component activity are high.This is compared with traditional fresh flower extraction process, and there are clear superiority, traditional fresh flower is mentioned
Taking technique can lose the active constituent in fresh flower significantly, so that obviously weakening the effect of product, the present invention is using the extraction optimized
Technique prepares fresh flower extract, so that the active constituent in product obtains maximum reservation, this extracting solution has pleasant day
The right fragrance of a flower, can substitute traditional artificial synthetic essence completely, and the safety of product also gets a promotion.
The four kinds of fresh flower extract combinations collocation prepared using optimization method of the invention is together of the invention to prepare
Lightening compositions, make obtained product have good whitening, skin lightening, moisturizing, it is anti-inflammatory, releive and other effects.
2, lightening compositions provided by the invention can inhibit the activity of tyrosinase, block melanin transport, inhibit black
Pigment is formed, and can be used in skin-lightening cosmetic, whitening, moisturizing, in terms of show excellent effect.
3, four kinds of fresh flower extract combinations are made an addition in lightening compositions of the invention, acts synergistically mutually, passes through work
Blood accelerates metabolism and the method for tyrosinase is inhibited to carry out whitening, and effect is very significant.
4, lightening compositions provided by the invention are highly-safe, can be adapted for various people.
5, added fresh flower extract is made according to preferred method, can retain the natural flavor of fresh flower itself, product
Woth no need to add artificial flavors and fragrances, the irritation of product can be reduced, the use provided as snug as a bug in a rug is felt.
6, natural fresh flower whitening composition is combined with the high synthesis whitening composition niacinamide of cost performance, Ke Yida
To more preferably whitening effect, while cost also can control within the scope of reasonable.
Detailed description of the invention
Fig. 1 is moisturizing test result.
Specific embodiment
Technical scheme is described further with reference to the accompanying drawing:
Examples 1 to 3 lightening compositions preparation example of the present invention
Examples 1 to 3 weighs each raw material according to formula as shown in table 1 below.
1 formula table of table (each number is mass percent in formula in table)
The lightening compositions of Examples 1 to 3 are prepared in accordance with the following steps:
1) xanthan gum in A group is soaked with butanediol, is then added in water phase pot, opened stirring, sequentially add in A group
Other remaining raw materials are warming up to 80 DEG C, 10 minutes are kept the temperature, until being completely dissolved.
2) mixing speed of emulsion pot is maintained at 300 revs/min, low by mixture obtained by step 1) by vacuum suck
Fast homogeneous 5 minutes.Start to cool down.
3) when dropping to 45 DEG C, each raw material of B group is added in emulsion pot, opens stirring, is uniformly mixed；
4) each raw material of C group is sequentially added in emulsion pot, is stirred evenly；
5) when stirring is cooled to 40 DEG C or less, each raw material of D group is added, stirring 10 minutes until uniformly；When being down to 38 DEG C
Filtering and discharging.
6) it is qualified to examine, and discharges filling.
Peony extract, safflower extract, Chinese herbaceous peony flower extract, Flos persicae extract in embodiment 1-3 respectively according to
Following steps preparation:
1) high-quality fresh, complete and free from admixture fresh petal, is selected, is put into grinding device after being cleaned up with pure water
It is ground into partial size≤80 mesh powder；
2), raw material powder is transported in supercritical extraction reactor, CO is inputted in supercritical extraction reactor2Fluid, CO2Flow velocity
For 15kg/h, extracting pressure is adjusted to 28MPa, extraction temperature is to be extracted at 30 DEG C, extraction 3 hours；
3) it, is exported from supercritical extraction reactor and takes out extraction mixture, mixture is input in overcritical separating still, separated
Pressure is adjusted to 6~8MPa, temperature is 35~36 DEG C, separates 2 hours；
It 4) is, that 1: 10 (unit g/L) is added to the water by solid-liquid ratio the above separation product, straight fire heating distillation 3 hours,
Steam condensing recovery obtains fresh flower extract.
Reference examples 1~3
Reference examples 1~3 weigh each component according to formula shown in table 1；
The preparation method of 1~3 lightening compositions of reference examples is repeated no more referring to the progress of Examples 1 to 3.
Efficacy test
One, long-acting whitening effect evaluation
Test sample: embodiment 1, embodiment 2, embodiment 3, reference examples 1, reference examples 2, reference examples 3
Test purpose: being used continuously skin-protection product by adult female volunteer under normal circumstances, assesses skin care production
The effect of product are in terms of whitening.
Volunteer's age: 25~44 years old
Gender: women
Volunteer's number: 180 people
Volunteer's face skin quality: blee is obscure, matt
Whitening effect: cheek
Product frequency of use: uniformly smearing after face cleaning, 2 times a day, once in the morning and once at night, produces using after product four weeks with use
After product eight weeks.
Test item: long-acting whitening effect
Appraisal procedure: by the way of questionnaire survey, 4 weeks and 8 weeks understanding subjects use product after using product
The evaluation of the improvement situation of the colour of skin afterwards.Judging quota is broadly divided into: whitening effect.As a result be divided into: effect is unobvious, effect one
As, it is more apparent, clearly.
1), after using product four weeks
Experiment conclusion:
28 days on probation whitening effects of each experimental group volunteer count display:
In 30 volunteers using embodiment 1, there is 50% volunteer to feel there is obviously whitening effect.
In 30 volunteers using embodiment 2, there is 53.3% volunteer to feel there is obviously whitening effect.
In 30 volunteers using embodiment 3, there is 60% volunteer to feel there is obviously whitening effect.
In 30 volunteers using reference examples 1, only 20% volunteer feels there is obviously whitening effect.
In 30 volunteers using reference examples 2, only 10% volunteer feels there is obviously whitening effect.
In 30 volunteers using reference examples 3, only 13.3% volunteer feels there is obviously whitening effect
Fruit.
The results show that Examples 1 to 4 contains the cleawhite over-night essences there are four types of fresh flower extracting solution, whitening effect is substantially better than pair
As usual.
2), using after product eight weeks
Experiment conclusion:
Using the volunteer of cleawhite over-night essences, 56 days whitening effects count display:
In 30 volunteers using embodiment 1, there is 56.7% volunteer to feel there is obviously whitening effect.
In 30 volunteers using embodiment 2, there is 60% volunteer to feel there is obviously whitening effect.
In 30 volunteers using embodiment 3, there is 66.7% volunteer to feel there is obviously whitening effect.
In 30 volunteers using reference examples 1, only 20% volunteer feels there is obviously whitening effect.
In 30 volunteers using reference examples 2, only 10% volunteer feels there is obviously whitening effect.
In 30 volunteers using reference examples 3, only 10% volunteer feels there is obviously whitening effect.
The results show that containing there are four types of the embodiment 1-3 cleawhite over-night essences of fresh flower extracting solution, whitening effect is substantially better than control
Example.
Two, performance of keeping humidity is assessed
Appraisal procedure:
1) tested material: embodiment 1, embodiment 2, embodiment 3, reference examples 1
2) subject: totally 30 people, male 10 people, 20 people of female the age 21~49 years old, meet subject and volunteer inclusion criteria.
3) sample of 70ul appraisal procedure: is applied to two wrist inside portions.Leading electrical rate measurement will be smeared and be set as 1, seen
Before examining smearing, 5,15,30,60 minutes numerical value changes after smearing.Successively evaluate the moisture retention of sample.
4) assessment result: the numerical value change of conductivity is observed, as a result as shown in Figure 1.
Experiment conclusion: the experimental results showed that, the moisture retention after embodiment 1,2,3 is smeared is significantly higher than reference examples 1.
During carrying out efficacy test, user indicates that the product of 1-3 of the embodiment of the present invention has the pleasant fragrance of a flower,
And product use is mild as snug as a bug in a rug, does not find any allergy or stimulation phenomenon.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.
Claims (6)
1. a kind of containing there are many lightening compositions of fresh flower, which is characterized in that each component including following mass percent: fourth two
Alcohol 1.0%~10.0%, xanthan gum 0.01%~0.8%, sodium lactate 1.0%~10.0%, panthenol 0.1%~5.0%, tree peony
Flower extract 0.1%~10.0%, safflower extract 0.1%~10.0%, Chinese herbaceous peony flower extract 0.1%~10.0%, peach blossom
Extract 0.1%~10.0%, niacinamide 0.1%~2.0%, Phenoxyethanol 0.1%~0.8%, pungent glycol 0.1%~
0.8%, surplus is deionized water；
The peony extract, safflower extract, Chinese herbaceous peony flower extract or Flos persicae extract are according to the side included the following steps
Method preparation:
1) petal is ground into powder；
2) powder of step 1) is added into supercritical extraction reactor, inputs CO 2 fluid into supercritical extraction reactor, two
Carbonoxide flow velocity is 10~20kg/h, and extracting pressure is 25~30MPa, and extraction temperature is 25~35 DEG C；
3) extraction gained mixture is taken out from supercritical extraction reactor, is fed the mixture into overcritical separating still, separation pressure
Power is 6~8MPa, and temperature is 35~36 DEG C；
4) separation product obtained by step 3) is added to the water by solid-liquid ratio 1:5~15g/L, heating distillation 2~4 hours, steam is cold
It is solidifying to recycle to obtain extract.
2. lightening compositions according to claim 1, which is characterized in that in step 1), petal is ground into partial size≤80
Purpose powder.
3. lightening compositions according to claim 1, which is characterized in that in step 2), extraction time is 2~4 hours.
4. lightening compositions according to claim 1, which is characterized in that in step 3), disengaging time is 1~3 hour.
5. lightening compositions according to claim 1, which is characterized in that in step 4), using straight fire heating distillation.
6. a kind of method for preparing lightening compositions as claimed in any one of claims 1 to 5, which is characterized in that including as follows
Step:
1) xanthan gum is soaked with butanediol, be added water phase pot in, under stirring, sequentially add sodium lactate, panthenol, go from
Sub- water is warming up to 80 DEG C, heat preservation, until being completely dissolved；
2) mixture obtained by step 1) is passed through in vacuum suck emulsion pot, homogeneous；
3) 40~50 DEG C are cooled to, niacinamide is added in emulsion pot, is stirred and evenly mixed；
4) peony extract, safflower extract, Chinese herbaceous peony flower extract and Flos persicae extract are added in emulsion pot, stirring is mixed
It is even；
5) 40 DEG C are cooled to hereinafter, stirring and evenly mixing in remaining components addition emulsion pot.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610882488.4A CN106309244B (en) | 2016-10-09 | 2016-10-09 | It is a kind of containing there are many lightening compositions of fresh flower and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108379182A (en) * | 2018-05-31 | 2018-08-10 | 傅清杰 | A Chinese medicine functional mask |
| CN110613650A (en) * | 2019-10-25 | 2019-12-27 | 上海伽誉生物科技有限公司 | Essence containing okra hydrolyzed glycoprotein SILKY-WSP and preparation method thereof |
| CN110693780A (en) * | 2019-10-31 | 2020-01-17 | 广东密尚生物科技有限公司 | Skin nourishing composition and application thereof, and skin nourishing mask liquid |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003012495A (en) * | 2001-07-06 | 2003-01-15 | Kanebo Ltd | Cosmetic |
| CN103830137A (en) * | 2014-01-20 | 2014-06-04 | 上海珈叶生物技术有限公司 | Plant extract composition with whitening effect, preparation and preparation method thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003012495A (en) * | 2001-07-06 | 2003-01-15 | Kanebo Ltd | Cosmetic |
| CN103830137A (en) * | 2014-01-20 | 2014-06-04 | 上海珈叶生物技术有限公司 | Plant extract composition with whitening effect, preparation and preparation method thereof |
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