CN106177692A - A kind of preparation method of the Chinese herbal medicine extract preparation driving away pig Enterozoa - Google Patents
A kind of preparation method of the Chinese herbal medicine extract preparation driving away pig Enterozoa Download PDFInfo
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- CN106177692A CN106177692A CN201610829247.3A CN201610829247A CN106177692A CN 106177692 A CN106177692 A CN 106177692A CN 201610829247 A CN201610829247 A CN 201610829247A CN 106177692 A CN106177692 A CN 106177692A
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- enterozoa
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The present invention provides a kind of Chinese medicine extract preparation driving away pig Enterozoa and preparation method thereof.Semen Torreyae, betel nut, Pericarpium Granati, Caulis Sargentodoxae, Radix Stemonae, Radix Asteris.Through parch, micronizing, soak extraction, second extraction, concentrate, be mixed to prepare.The weight proportion scope of the most each Chinese crude drug is: Semen Torreyae 30~35 parts, betel nut 20~25 parts, Pericarpium Granati 15~20 parts, Caulis Sargentodoxae 12~18 parts, Radix Stemonae 8~13 parts, Radix Asteris 5~10 parts.The product of the present invention is mixed in feedstuff in 1:500 ratio, begins to use during weaned piglet, be used in conjunction 2~3, used once every 15~20 days afterwards.Easy to use, effect is obvious, low cost, and to pig nonhazardous effect, biological safety is high.
Description
Technical field
The present invention relates to a kind of Chinese medicine extract preparation driving away pig Enterozoa and preparation method thereof.
Background technology
During current intensive pig production produces, owing to the density of swinery is high, the number of animals raised is big, for the propagation of parasite
Bringing favourable condition, parasite is i.e. that a kind of class residing in host inner or in vitro is biological, they mainly by
Host is as the source of food and growth promoter and the place of breeding, and can make host infection parasitic disease, brings to host
It is dead that harm even causes it.Popular parasite substantially can be divided into three major types, i.e. nematode, demodicid mite class and protozoon class.Common
Parasite species is balantidium Coli, pig coccidiosis, Trichocephalus, ascaris suum, Oesophagostomum, acaricide and Eperythrozoon
Deng
Owing to not resulting in acute death after infecting parasite, they produced symptom and harm in pathogenic course are all gradually
That enter, slowly, typically will not as bacillary, viral disease come fierce, unexpected, this allows for pig farmer and works anthelmintic
Ignorance.But, parasitic infection can make growing-finishing pigs speed decline 8-15%, and efficiency of feed utilization declines 13-25%, to economy
Efficiency is very big.And the existence of parasitic disease can cause clinical application difficulty, owing to being accustomed to the impact of thinking, goes out clinically
Existing symptom of diarrhea selects antibacterial dysentery relieving medicine the most immediately;Occur that respiratory symptom is taken as antibacterial, virus infects, often result in
In treatment not in time or mistaken diagnosis.So anthelmintic work is the important step that a lot of plant can not ignore, but the most much drive
Worm medicine owing to using effect is inconspicuous, drug toxicity compared with big, palatability is poor, allows the friend that much raises pigs produce the selection of anthelmintic
Give birth to doubt.
Summary of the invention
The technical problem to be solved is to provide a kind of efficient, safety, nothing for driving away pig Enterozoa
Chinese medicine extract preparation of residual and preparation method thereof.
The scheme of the technical problem to be solved is:
A kind of Chinese medicine extract preparation driving away pig Enterozoa, the weight proportion scope of raw material is: Semen Torreyae 30~35 parts, Bin
Bulky sub 20~25 parts, Pericarpium Granati 15~20 parts, Caulis Sargentodoxae 12~18 parts, Radix Stemonae 8~13 parts, Radix Asteris 5~10 parts.
Conventional weight proportion is: Semen Torreyae 30 parts, betel nut 25 parts, Pericarpium Granati 15 parts, Caulis Sargentodoxae 15 parts, Radix Stemonae 10 parts, purple
5 parts of garden.
The present invention is achieved in that 1, by the parch in frying machine of Semen Torreyae, betel nut, Caulis Sargentodoxae, be cooled to room temperature;2, will
The complete Semen Torreyae of parch, betel nut, Caulis Sargentodoxae, Pericarpium Granati, Radix Stemonae carry out micronizing, by Radix Asteris powder micronizing;3, by Radix Asteris
Powder soak extraction;4, the Radix Asteris extracting solution extracted for the first time is carried out second extraction;5, after twice extracting solution being mixed dense
Contracting;6, concentrated solution is mixed homogeneously with the fine powder after pulverizing.
The above-mentioned parch time is 1 hour;Described micronizing, is ground into after the most above-mentioned each component being mixed
The fine powder of 200 mesh;Described soak extraction, is that the medicated powder crushed is little with soaking 3 under the clear water room temperature of 5 times of drug weight
Time;Described secondary soak extraction, will for the first time after soak extraction isolated medicine residue again by 5 times of former medicated powder weight
Soak 3 hours under clear water room temperature;Described admixing medical solutions, will be mixed with the extracting solution of second time soak extraction gained for the first time
Close;Described concentration, the concentration of liquid medicine that will extract becomes the concentrated solution of 1 times of former medicated powder weight.
The invention has the beneficial effects as follows:
1, anthelmintic Enterozoa effect is obvious;
2 mix with feedstuff, easy to use, low cost;
3, it is Chinese medicine preparation due to the present invention, therefore, to pig nonhazardous effect, in pig body, remains low even noresidue.
The using method of the present invention is: is mixed in feedstuff in 1:500 ratio by the product of the present invention, opens during weaned piglet
Begin to use, be used in conjunction 2~3, used once every 15~20 days afterwards, can effectively drive away Enterozoa.
Detailed description of the invention:
The following is embodiments of the invention, the actually used of the present invention is not limited to embodiment.
Embodiment one:
The preparation method using the Chinese medicine extract preparation driving away pig Enterozoa of the present invention prepares this Chinese medicine extract system
Agent, takes crude drug 100kg altogether, and the weight of each crude drug is respectively as follows: Semen Torreyae 30kg, betel nut 20kg, Pericarpium Granati 20kg, Caulis Sargentodoxae
16kg, Radix Stemonae 8kg, Radix Asteris 6kg.By Semen Torreyae, betel nut, Caulis Sargentodoxae parch 1 hour in frying machine, it is cooled to room temperature;To fry
The Semen Torreyae made, betel nut, Caulis Sargentodoxae, Pericarpium Granati, Radix Stemonae superfine powder are broken into the fine powder of 200 mesh, are broken into by Radix Asteris powder superfine powder
The fine powder of 200 mesh;Tatarian Aster Root is soaked 3 hours with under the clear water room temperature of 5 times of i.e. 30kg of weight;Separate medicinal liquid residual with medicine
Slag, leaves and takes medicinal liquid standby, more isolated medicine residue adds immersion 3 hours under the clear water room temperature of 5 times of former medicated powder weight, point
Separate out medicinal liquid, after being mixed by the medicinal liquid of twice extraction, be condensed into the concentrated solution of 1 times of former medicated powder weight;After concentrated solution and pulverizing
After fine powder mix homogeneously, subpackage prepares finished product.
Nursery pig 400 is raised on Zhenjiang, Jiangsu one pig farm, has 48 ablactational baby pig to seem mental status fair, and diet is also
More normal, but weight is less than normal compared with brood piglet, by hair slightly disorderly, physique slight of stature, average every day, length was less than 50g.Root
Determine owing to parasite is caused according to clinical symptoms and etiological examination, the Chinese medicine extract system that should prepare in aforementioned manners
Agent is mixed in feedstuff in 1:500 ratio, is used in conjunction 3.After medication 3 days, daily gain reaches 400g, and the state of an illness has obtained effective control.
Embodiment two:
The preparation method using the Chinese medicine extract preparation driving away pig Enterozoa of the present invention prepares this Chinese medicine extract system
Agent, takes crude drug 80kg altogether, and the weight of each crude drug is respectively as follows: Semen Torreyae 26kg, betel nut 16kg, Pericarpium Granati 10kg, Caulis Sargentodoxae
12kg, Radix Stemonae 8kg, Radix Asteris 8kg.By Semen Torreyae, betel nut, Caulis Sargentodoxae parch 1 hour in frying machine, it is cooled to room temperature;To fry
The Semen Torreyae made, betel nut, Caulis Sargentodoxae, Pericarpium Granati, Radix Stemonae superfine powder are broken into the fine powder of 200 mesh, are broken into by Radix Asteris powder superfine powder
The fine powder of 200 mesh;Tatarian Aster Root is soaked 3 hours with under the clear water room temperature of 5 times of i.e. 40kg of weight;Separate medicinal liquid residual with medicine
Slag, leaves and takes medicinal liquid standby, more isolated medicine residue adds immersion 3 hours under the clear water room temperature of 5 times of former medicated powder weight, point
Separate out medicinal liquid, after being mixed by the medicinal liquid of twice extraction, be condensed into the concentrated solution of 1 times of former medicated powder weight;After concentrated solution and pulverizing
After fine powder mix homogeneously, subpackage prepares finished product.
There is poor growth in pig farm 100, Huaian one bull nursery pig, and efficiency of feed utilization declines, and occurs that some are breathed simultaneously
Road symptom, parasitic infection ratio is more serious.After the Chinese medicine extract preparation that should prepare in aforementioned manners is according to 1:500 ratio spice
Using to nursery pig, be used in conjunction 3 days, after medication 3 days, sick pig symptom substantially alleviates, and after 15 days, second time medication, is used in conjunction symptom after 2 days
It is wholly absent.
Embodiment three:
The preparation method using the Chinese medicine extract preparation driving away pig Enterozoa of the present invention prepares this Chinese medicine extract system
Agent, takes crude drug 150kg altogether, and the weight of each crude drug is respectively as follows: Semen Torreyae 45kg, betel nut 38kg, Pericarpium Granati 23kg, Caulis Sargentodoxae
22kg, Radix Stemonae 15kg, Radix Asteris 7kg.By Semen Torreyae, betel nut, Caulis Sargentodoxae parch 1 hour in frying machine, it is cooled to room temperature;To fry
The Semen Torreyae made, betel nut, Caulis Sargentodoxae, Pericarpium Granati, Radix Stemonae superfine powder are broken into the fine powder of 200 mesh, are broken into by Radix Asteris powder superfine powder
The fine powder of 200 mesh;Tatarian Aster Root is soaked 3 hours with under the clear water room temperature of 5 times of i.e. 35kg of weight;Separate medicinal liquid residual with medicine
Slag, leaves and takes medicinal liquid standby, more isolated medicine residue adds immersion 3 hours under the clear water room temperature of 5 times of former medicated powder weight, point
Separate out medicinal liquid, after being mixed by the medicinal liquid of twice extraction, be condensed into the concentrated solution of 1 times of former medicated powder weight;After concentrated solution and pulverizing
After fine powder mix homogeneously, subpackage prepares finished product.
Pig farm, Yantai, Shandong one ablactational baby pig generation parasitic infection, the preventing and treating mycoplasma pneumoniae of swine that should prepare in aforementioned manners
Chinese medicine extract preparation mix in feedstuff according to 1:500, be used in conjunction 3 days, after 15 days second time medication, after being used in conjunction 3 days well
Control the state of an illness.
Claims (3)
1. the Chinese medicine extract preparation driving away pig Enterozoa, it is characterised in that: its constituent ratio range is: Chinese torreya
Son 30~35 parts, betel nut 20~25 parts, Pericarpium Granati 15~20 parts, Caulis Sargentodoxae 12~18 parts, Radix Stemonae 8~13 parts, Radix Asteris 5~10
Part.
A kind of Chinese medicine extract preparation driving away pig Enterozoa the most as claimed in claim 1, it is characterised in that: raw material is normal
With weight proportion it is: Semen Torreyae 30 parts, betel nut 25 parts, Pericarpium Granati 15 parts, Caulis Sargentodoxae 15 parts, Radix Stemonae 10 parts, Radix Asteris 5 parts.
3. the preparation method of a kind of Chinese medicine extract preparation driving away pig Enterozoa as described in claim 1 and 2, it is special
Levy and be: 1, by Semen Torreyae, betel nut, Caulis Sargentodoxae parch 1 hour in frying machine, be cooled to room temperature;2, by Semen Torreyae complete for parch, Bin
Bulky son, Caulis Sargentodoxae, Pericarpium Granati, Radix Stemonae carry out superfine powder and are broken into 200 mesh fine powders, and Radix Asteris powder superfine powder is broken into 200 mesh fine powders;3、
Tatarian Aster Root adds 5 times of water soakings within 3 hours, extract;4, the Radix Asteris extracting solution extracted for the first time is added 5 times of water and carry out second extraction;5、
The concentrated solution of 1 times of former medicated powder weight will be condensed into after twice extracting solution mixing;6, concentrated solution is mixed all with the fine powder after pulverizing
Even.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107410370A (en) * | 2017-06-11 | 2017-12-01 | 徐州得铸生物科技有限公司 | A kind of mosquitocide |
CN113558008A (en) * | 2021-07-20 | 2021-10-29 | 中国科学院动物研究所 | Medium-transmitted disease control method based on foraging of small mammals |
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CN103566252A (en) * | 2012-07-27 | 2014-02-12 | 严括 | Traditional Chinese medicine composition for treating ancylostomiasis |
CN104162069A (en) * | 2013-05-20 | 2014-11-26 | 杨国俊 | Traditional Chinese medicine composition for treating ancylostomiasis |
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2016
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Patent Citations (3)
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CN103566252A (en) * | 2012-07-27 | 2014-02-12 | 严括 | Traditional Chinese medicine composition for treating ancylostomiasis |
CN104162069A (en) * | 2013-05-20 | 2014-11-26 | 杨国俊 | Traditional Chinese medicine composition for treating ancylostomiasis |
CN103495136A (en) * | 2013-09-30 | 2014-01-08 | 河南亚卫动物药业有限公司 | Fermented Chinese herbal medicine for treating livestock gastrointestinal tract parasitic disease and preparation method of fermented Chinese herbal medicine |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107410370A (en) * | 2017-06-11 | 2017-12-01 | 徐州得铸生物科技有限公司 | A kind of mosquitocide |
CN113558008A (en) * | 2021-07-20 | 2021-10-29 | 中国科学院动物研究所 | Medium-transmitted disease control method based on foraging of small mammals |
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Application publication date: 20161207 |