CN106176943A - A kind of poultry compound medicine containing Cortex Cinnamomi and LIJUNJING - Google Patents
A kind of poultry compound medicine containing Cortex Cinnamomi and LIJUNJING Download PDFInfo
- Publication number
- CN106176943A CN106176943A CN201610705303.2A CN201610705303A CN106176943A CN 106176943 A CN106176943 A CN 106176943A CN 201610705303 A CN201610705303 A CN 201610705303A CN 106176943 A CN106176943 A CN 106176943A
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- CN
- China
- Prior art keywords
- lijunjing
- cortex cinnamomi
- compound medicine
- poultry
- poultry compound
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a kind of poultry compound medicine containing Cortex Cinnamomi and LIJUNJING, be made up of LIJUNJING and Cortex Cinnamomi, the weight ratio of LIJUNJING and Cortex Cinnamomi is 1:3 1:5.The present invention is also claimed by the compound preparation become prepared by above-mentioned poultry compound medicine.The present invention possesses and provides the benefit that: proving through experimental study, LIJUNJING is used in combination with specific part by weight with Cortex Cinnamomi, has synergism obvious, and curative effect is fast, low cost and other advantages.
Description
Technical field
The invention belongs to poultry compound medicine technical field, particularly relate to a kind of poultry containing Cortex Cinnamomi and LIJUNJING with multiple
Side's medicine, the disease caused for treating poultry to be infected by colon bacillus.
Background technology
After poultry are infected by colon bacillus, the multiple locations such as acute sepsis, peritonitis, hepatitis, pneumonia, enteritis can be caused
Severe infections, causes huge economic loss to livestock and poultry cultivation.LIJUNJING, norfloxacin, florfenicol etc. are to prevent and treat this type of disease
Sick conventional Western medicine, along with medication is more and more spread unchecked, its Resistant strain is the most, and drug cost is the most increasing, but controls
Therapeutic effect and drug resistance situation are not taken a turn for the better, and go from bad to worse on the contrary.
Through retrieval, do not inquire Cortex Cinnamomi and LIJUNJING are combined for treat poultry by colon bacillus infect cause
The relevant report of disease.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of poultry compound medicine containing Cortex Cinnamomi and LIJUNJING, and it is worked in coordination with
Effect is substantially, it is possible to eliminate the colon bacillus drug resistance to LIJUNJING, improves therapeutic effect.
For solving above technical problem, the present invention by the following technical solutions: a kind of poultry containing Cortex Cinnamomi and LIJUNJING are used
Compound medicine, is made up of LIJUNJING and Cortex Cinnamomi, and the weight ratio of LIJUNJING and Cortex Cinnamomi is 1:3-1:5.
The present invention is also claimed by the compound preparation become prepared by above-mentioned poultry compound medicine.
The present invention possesses and provides the benefit that: proving through experimental study, LIJUNJING joins with specific part by weight with Cortex Cinnamomi
Closing and use, have synergism obvious, curative effect is fast, low cost and other advantages.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme and beneficial effect are described further, except Special Statement
Outward, Cortex Cinnamomi weight of the present invention is the dry weight of Cortex Cinnamomi.
One, the Cortex Cinnamomi mensuration to the drug resistance elimination effect of LIJUNJING
1. assay method
It is the mixing medicine that 1:1,1:3,1:5,1:10,1:30,1:50 prepare Cortex Cinnamomi and various Western medicine respectively according to weight ratio
Liquid;Choose the bacterial strain to Western medicine drug resistance as subjects, utilize plate dilution method to carry out Secondary Culture, measure each process medicinal liquid
MIC situation of change to Resistant strain;Set the Western medicine being not added with Cortex Cinnamomi to compare as sun, if it is right as the moon to be not added with Cortex Cinnamomi and Western medicine simultaneously
According to.
Above-mentioned process was cultivated for 4 generations the most continuously.
2. result of the test
After cultivating for 4 generations continuously, the process flat board of cloudy comparison is long bacterium, and other each medicaments and admixing medical solutions are for large intestine angstrom
The result statistics of the MIC of uncommon Salmonella is as shown in table 1:
As seen from the above table, when the weight ratio of LIJUNJING Yu Cortex Cinnamomi is 1:3 and 1:5, LIJUNJING is to drug resistance E
The minimal inhibitory concentration of bacterium all reduces more than 32 times, it is seen then that the drug resistance of LIJUNJING is substantially reduced by drug resistance colon bacillus.
And when the weight ratio of LIJUNJING Yu Cortex Cinnamomi is 1:1,1:10,1:30 and 1:50, drug resistance large intestine angstrom is wished by LIJUNJING
The minimal inhibitory concentration of Salmonella, compared with the sun comparison being not added with Cortex Cinnamomi, does not has significant change.
Two, the experiment in vitro that LIJUNJING and Cortex Cinnamomi are used in combination
It is 1:5 mixing by LIJUNJING and Cortex Cinnamomi (powder) according to weight ratio, makes powder, as test group;Separately set LIJUNJING
Single dose and Cortex Cinnamomi single dose as a control group 1 and matched group 2.
Subjects is the chicken group making a definite diagnosis and having infected E.coli from chickens disease.
Morbidity chicken group is divided into 3 groups of administrations.Test group is administered according to the addition of 1g/kg feedstuff, and matched group 1 uses LIJUNJING
Single dose is administered according to the addition of 0.2g/kg feedstuff, and matched group 2 Cortex Cinnamomi single dose is administered according to the addition of 1g/kg feedstuff;Respectively
Organize equal SM 5 days.
Result of the test: the sick chicken feed intake of test group increased, without dead, after using 5 days, chicken group can fully recover;Comparison
Chicken group's great majority still wan of group 1, has the sick chicken death of 4%;Chicken group's great majority of matched group 2 are also still wans, have
The sick chicken death of 13%.
Claims (2)
1. one kind contains Cortex Cinnamomi and the poultry compound medicine of LIJUNJING, it is characterised in that be made up of LIJUNJING and Cortex Cinnamomi, LIJUNJING
It is 1:3-1:5 with the weight ratio of Cortex Cinnamomi.
2. by the compound preparation become prepared by the poultry compound medicine described in claim 1.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610705303.2A CN106176943A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Cortex Cinnamomi and LIJUNJING |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610705303.2A CN106176943A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Cortex Cinnamomi and LIJUNJING |
Publications (1)
Publication Number | Publication Date |
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CN106176943A true CN106176943A (en) | 2016-12-07 |
Family
ID=57523820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610705303.2A Withdrawn CN106176943A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Cortex Cinnamomi and LIJUNJING |
Country Status (1)
Country | Link |
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CN (1) | CN106176943A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103961421A (en) * | 2014-05-14 | 2014-08-06 | 广西大学 | Compound medicine containing radix paeoniae rubra and mequindox for livestock and poultry |
CN104367601A (en) * | 2014-11-12 | 2015-02-25 | 广西大学 | Compound medicine containing herba pteridis multifidae and mequindox for livestock and poultry |
CN104435038A (en) * | 2014-11-07 | 2015-03-25 | 广西大学 | Balsamiferou blumea herb and mequindox containing compound medicine for livestock and poultry |
-
2016
- 2016-08-22 CN CN201610705303.2A patent/CN106176943A/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103961421A (en) * | 2014-05-14 | 2014-08-06 | 广西大学 | Compound medicine containing radix paeoniae rubra and mequindox for livestock and poultry |
CN104435038A (en) * | 2014-11-07 | 2015-03-25 | 广西大学 | Balsamiferou blumea herb and mequindox containing compound medicine for livestock and poultry |
CN104367601A (en) * | 2014-11-12 | 2015-02-25 | 广西大学 | Compound medicine containing herba pteridis multifidae and mequindox for livestock and poultry |
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C06 | Publication | ||
PB01 | Publication | ||
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WW01 | Invention patent application withdrawn after publication |
Application publication date: 20161207 |
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WW01 | Invention patent application withdrawn after publication |