CN106176897A - A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and LIJUNJING - Google Patents
A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and LIJUNJING Download PDFInfo
- Publication number
- CN106176897A CN106176897A CN201610705501.9A CN201610705501A CN106176897A CN 106176897 A CN106176897 A CN 106176897A CN 201610705501 A CN201610705501 A CN 201610705501A CN 106176897 A CN106176897 A CN 106176897A
- Authority
- CN
- China
- Prior art keywords
- lijunjing
- herba euphorbiae
- euphorbiae humifusae
- compound medicine
- poultry
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a kind of poultry compound medicine containing Herba Euphorbiae Humifusae and LIJUNJING, be made up of LIJUNJING and Herba Euphorbiae Humifusae, the weight ratio of LIJUNJING and Herba Euphorbiae Humifusae is 1:1 1:5.The present invention is also claimed by the compound preparation become prepared by above-mentioned poultry compound medicine.The present invention possesses and provides the benefit that: proving through experimental study, LIJUNJING is used in combination with specific part by weight with Herba Euphorbiae Humifusae, has synergism obvious, and curative effect is fast, low cost and other advantages.
Description
Technical field
The invention belongs to poultry compound medicine technical field, particularly relate to a kind of poultry containing Herba Euphorbiae Humifusae and LIJUNJING and use
Compound medicine, the disease caused for treating poultry to be infected by colon bacillus.
Background technology
After poultry are infected by colon bacillus, the multiple locations such as acute sepsis, peritonitis, hepatitis, pneumonia, enteritis can be caused
Severe infections, causes huge economic loss to livestock and poultry cultivation.LIJUNJING, norfloxacin, florfenicol etc. are to prevent and treat this type of disease
Sick conventional Western medicine, along with medication is more and more spread unchecked, its Resistant strain is the most, and drug cost is the most increasing, but controls
Therapeutic effect and drug resistance situation are not taken a turn for the better, and go from bad to worse on the contrary.
Through retrieval, do not inquire Herba Euphorbiae Humifusae and LIJUNJING are combined for treat poultry by colon bacillus infect draw
The relevant report of the disease risen.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of poultry compound medicine containing Herba Euphorbiae Humifusae and LIJUNJING, its association
Same-action is obvious, it is possible to eliminate the colon bacillus drug resistance to LIJUNJING, improves therapeutic effect.
For solving above technical problem, the present invention by the following technical solutions: a kind of containing Herba Euphorbiae Humifusae with the poultry of LIJUNJING
With compound medicine, being made up of LIJUNJING and Herba Euphorbiae Humifusae, the weight ratio of LIJUNJING and Herba Euphorbiae Humifusae is 1:1-1:5.
The present invention is also claimed by the compound preparation become prepared by above-mentioned poultry compound medicine.
The present invention possesses and provides the benefit that: prove through experimental study, and LIJUNJING and Herba Euphorbiae Humifusae are with specific part by weight
Being used in combination, have synergism obvious, curative effect is fast, low cost and other advantages.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme and beneficial effect are described further, except Special Statement
Outward, Herba Euphorbiae Humifusae weight of the present invention is the dry weight of Herba Euphorbiae Humifusae.
One, the Herba Euphorbiae Humifusae mensuration to the drug resistance elimination effect of LIJUNJING
1. assay method
It is the mixing that 1:1,1:3,1:5,1:10,1:30,1:50 prepare Herba Euphorbiae Humifusae and various Western medicine respectively according to weight ratio
Medicinal liquid；Choose the bacterial strain to Western medicine drug resistance as subjects, utilize plate dilution method to carry out Secondary Culture, measure each process medicine
The liquid MIC situation of change to Resistant strain；Set the Western medicine being not added with Herba Euphorbiae Humifusae to compare as sun, if being not added with Herba Euphorbiae Humifusae and Western medicine work simultaneously
Compare for the moon.
Above-mentioned process was cultivated for 4 generations the most continuously.
2. result of the test
After cultivating for 4 generations continuously, the process flat board of cloudy comparison is long bacterium, and other each medicaments and admixing medical solutions are for large intestine angstrom
The result statistics of the MIC of uncommon Salmonella is as shown in table 1:
As seen from the above table, when the weight ratio of LIJUNJING Yu Herba Euphorbiae Humifusae is 1:1,1:3 and 1:5, LIJUNJING is to drug resistance large intestine
The minimal inhibitory concentration of Escherichia all reduces more than 32 times, it is seen then that drug resistance colon bacillus is bright to the drug resistance of LIJUNJING
Aobvious reduction.
And when the weight ratio of LIJUNJING Yu Herba Euphorbiae Humifusae is 1:10,1:30 and 1:50, LIJUNJING is to drug resistance E
The minimal inhibitory concentration of bacterium, compared with the sun comparison being not added with Herba Euphorbiae Humifusae, does not has significant change.
Two, the experiment in vitro that LIJUNJING and Herba Euphorbiae Humifusae are used in combination
It is 1:5 mixing by LIJUNJING and Herba Euphorbiae Humifusae (powder) according to weight ratio, makes powder, as test group；Separately set dysentery bacterium
Clean single dose and Herba Euphorbiae Humifusae single dose as a control group 1 and matched group 2.
Subjects is the chicken group making a definite diagnosis and having infected E.coli from chickens disease.
Morbidity chicken group is divided into 3 groups of administrations.Test group is administered according to the addition of 1g/kg feedstuff, and matched group 1 uses LIJUNJING
Single dose is administered according to the addition of 0.2g/kg feedstuff, and matched group 2 Herba Euphorbiae Humifusae single dose is administered according to the addition of 1g/kg feedstuff；
The equal SM of each group 5 days.
Result of the test: the sick chicken feed intake of test group increased, without dead, after using 5 days, chicken group can fully recover；Comparison
Chicken group's great majority still wan of group 1, has the sick chicken death of 3%；Chicken group's great majority of matched group 2 are also still wans, have 6%
Sick chicken death.
Claims (2)
1. one kind contains Herba Euphorbiae Humifusae and the poultry compound medicine of LIJUNJING, it is characterised in that be made up of LIJUNJING and Herba Euphorbiae Humifusae, dysentery
Clean and Herba Euphorbiae Humifusae the weight ratio of bacterium is 1:1-1:5.
2. by the compound preparation become prepared by the poultry compound medicine described in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610705501.9A CN106176897A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and LIJUNJING |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610705501.9A CN106176897A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and LIJUNJING |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106176897A true CN106176897A (en) | 2016-12-07 |
Family
ID=57524736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610705501.9A Withdrawn CN106176897A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and LIJUNJING |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106176897A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728479A (en) * | 2016-12-16 | 2017-05-31 | 范明忠 | A kind of livestock and poultry compound medicine containing treebine stem and LIJUNJING |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103961421A (en) * | 2014-05-14 | 2014-08-06 | 广西大学 | Compound medicine containing radix paeoniae rubra and mequindox for livestock and poultry |
| CN103989727A (en) * | 2014-05-28 | 2014-08-20 | 广西大学 | Acalypha australis L. and mequindox containing compound medicine for livestock and poultry |
| CN104027370A (en) * | 2013-06-13 | 2014-09-10 | 广西南宁市桃源兽药厂 | Plumbago zeylanica and mequindox containing compound composition for livestock and poultry |
-
2016
- 2016-08-22 CN CN201610705501.9A patent/CN106176897A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104027370A (en) * | 2013-06-13 | 2014-09-10 | 广西南宁市桃源兽药厂 | Plumbago zeylanica and mequindox containing compound composition for livestock and poultry |
| CN103961421A (en) * | 2014-05-14 | 2014-08-06 | 广西大学 | Compound medicine containing radix paeoniae rubra and mequindox for livestock and poultry |
| CN103989727A (en) * | 2014-05-28 | 2014-08-20 | 广西大学 | Acalypha australis L. and mequindox containing compound medicine for livestock and poultry |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728479A (en) * | 2016-12-16 | 2017-05-31 | 范明忠 | A kind of livestock and poultry compound medicine containing treebine stem and LIJUNJING |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106176897A (en) | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and LIJUNJING | |
| CN106109638A (en) | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and LIJUNJING | |
| CN106138318A (en) | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and amoxicillin | |
| CN106109549A (en) | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and norfloxacin | |
| CN106138320A (en) | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and norfloxacin | |
| CN106176895A (en) | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and amoxicillin | |
| CN106267152A (en) | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and colistin | |
| CN106176942A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi and norfloxacin | |
| CN106267153A (en) | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and colistin | |
| CN106176943A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi and LIJUNJING | |
| CN106177904A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi and colistin | |
| CN106109547A (en) | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and fosfomycin | |
| CN106176894A (en) | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and sulfamonomethoxine sodium | |
| CN106109548A (en) | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and florfenicol | |
| CN106266049A (en) | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and sulfamonomethoxine sodium | |
| CN106139121A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi, Fructus Rosae Laevigatae and colistin | |
| CN106109578A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi and amoxicillin | |
| CN106176941A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi and florfenicol | |
| CN106109577A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi and sulfamonomethoxine sodium | |
| CN106138319A (en) | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and florfenicol | |
| CN106214742A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi and ceftiofur sodium | |
| CN106176896A (en) | A kind of poultry compound medicine containing Herba Euphorbiae Humifusae and amikacin | |
| CN106166184A (en) | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and amikacin | |
| CN106176944A (en) | A kind of poultry compound medicine containing Cortex Cinnamomi and amikacin | |
| CN106236879A (en) | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and ceftiofur sodium |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20161207 |
|
| WW01 | Invention patent application withdrawn after publication |