CN106109638A - A kind of poultry compound medicine containing Fructus Rosae Laevigatae and LIJUNJING - Google Patents
A kind of poultry compound medicine containing Fructus Rosae Laevigatae and LIJUNJING Download PDFInfo
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- CN106109638A CN106109638A CN201610704773.7A CN201610704773A CN106109638A CN 106109638 A CN106109638 A CN 106109638A CN 201610704773 A CN201610704773 A CN 201610704773A CN 106109638 A CN106109638 A CN 106109638A
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- Prior art keywords
- lijunjing
- fructus rosae
- rosae laevigatae
- compound medicine
- poultry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
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- Mycology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to a kind of poultry compound medicine containing Fructus Rosae Laevigatae and LIJUNJING, be made up of LIJUNJING and Fructus Rosae Laevigatae, the weight ratio of LIJUNJING and Fructus Rosae Laevigatae is 1:1 1:5.The present invention is also claimed by the compound preparation become prepared by above-mentioned poultry compound medicine.The present invention possesses and provides the benefit that: proving through experimental study, LIJUNJING is used in combination with specific part by weight with Fructus Rosae Laevigatae, has synergism obvious, and curative effect is fast, low cost and other advantages.
Description
Technical field
The invention belongs to poultry compound medicine technical field, particularly relate to a kind of poultry containing Fructus Rosae Laevigatae and LIJUNJING and use
Compound medicine, the disease caused for treating poultry to be infected by colon bacillus.
Background technology
After poultry are infected by colon bacillus, the multiple locations such as acute sepsis, peritonitis, hepatitis, pneumonia, enteritis can be caused
Severe infections, causes huge economic loss to livestock and poultry cultivation.LIJUNJING, norfloxacin, florfenicol etc. are to prevent and treat this type of disease
Sick conventional Western medicine, along with medication is more and more spread unchecked, its Resistant strain is the most, and drug cost is the most increasing, but controls
Therapeutic effect and drug resistance situation are not taken a turn for the better, and go from bad to worse on the contrary.
Through retrieval, do not inquire Fructus Rosae Laevigatae and LIJUNJING are combined for treat poultry by colon bacillus infect draw
The relevant report of the disease risen.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of poultry compound medicine containing Fructus Rosae Laevigatae and LIJUNJING, its association
Same-action is obvious, it is possible to eliminate the colon bacillus drug resistance to LIJUNJING, improves therapeutic effect.
For solving above technical problem, the present invention by the following technical solutions: a kind of containing Fructus Rosae Laevigatae with the poultry of LIJUNJING
With compound medicine, being made up of LIJUNJING and Fructus Rosae Laevigatae, the weight ratio of LIJUNJING and Fructus Rosae Laevigatae is 1:1-1:5.
The present invention is also claimed by the compound preparation become prepared by above-mentioned poultry compound medicine.
The present invention possesses and provides the benefit that: prove through experimental study, and LIJUNJING and Fructus Rosae Laevigatae are with specific part by weight
Being used in combination, have synergism obvious, curative effect is fast, low cost and other advantages.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme and beneficial effect are described further, except Special Statement
Outward, Fructus Rosae Laevigatae weight of the present invention is the dry weight of Fructus Rosae Laevigatae.
One, the Fructus Rosae Laevigatae mensuration to the drug resistance elimination effect of LIJUNJING
1. assay method
It is the mixing that 1:1,1:3,1:5,1:10,1:30,1:50 prepare Fructus Rosae Laevigatae and various Western medicine respectively according to weight ratio
Medicinal liquid；Choose the bacterial strain to Western medicine drug resistance as subjects, utilize plate dilution method to carry out Secondary Culture, measure each process medicine
The liquid MIC situation of change to Resistant strain；Set the Western medicine being not added with Fructus Rosae Laevigatae to compare as sun, if being not added with Fructus Rosae Laevigatae and Western medicine work simultaneously
Compare for the moon.
Above-mentioned process was cultivated for 4 generations the most continuously.
2. result of the test
After cultivating for 4 generations continuously, the process flat board of cloudy comparison is long bacterium, and other each medicaments and admixing medical solutions are for large intestine angstrom
The result statistics of the MIC of uncommon Salmonella is as shown in table 1:
As can be known from the above table, when the weight ratio of LIJUNJING Yu Fructus Rosae Laevigatae is 1:1,1:3 and 1:5, LIJUNJING is to drug resistance large intestine
The minimal inhibitory concentration of Escherichia all reduces more than 32 times, it is seen then that drug resistance colon bacillus is bright to the drug resistance of LIJUNJING
Aobvious reduction.
And when the weight ratio of LIJUNJING Yu Fructus Rosae Laevigatae is 1:10,1:30 and 1:50, LIJUNJING is to drug resistance E
The minimal inhibitory concentration of bacterium, compared with the sun comparison being not added with Fructus Rosae Laevigatae, does not has significant change.
Two, the experiment in vitro that LIJUNJING and Fructus Rosae Laevigatae are used in combination
It is 1:5 mixing by LIJUNJING and Fructus Rosae Laevigatae (powder) according to weight ratio, makes powder, as test group；Separately set dysentery bacterium
Clean single dose and Fructus Rosae Laevigatae single dose as a control group 1 and matched group 2.
Subjects is the chicken group making a definite diagnosis and having infected E.coli from chickens disease.
Morbidity chicken group is divided into 3 groups of administrations.Test group is administered according to the addition of 1g/kg feedstuff, and matched group 1 uses LIJUNJING
Single dose is administered according to the addition of 0.2g/kg feedstuff, and matched group 2 Fructus Rosae Laevigatae single dose is administered according to the addition of 1g/kg feedstuff；
The equal SM of each group 5 days.
Result of the test: the sick chicken feed intake of test group increased, without dead, after using 5 days, chicken group can fully recover；Comparison
Chicken group's great majority still wan of group 1, has the sick chicken death of 2%；Chicken group's great majority of matched group 2 are also still wans, have 3%
Sick chicken death.
Claims (2)
1. one kind contains Fructus Rosae Laevigatae and the poultry compound medicine of LIJUNJING, it is characterised in that be made up of LIJUNJING and Fructus Rosae Laevigatae, dysentery
Clean and Fructus Rosae Laevigatae the weight ratio of bacterium is 1:1-1:5.
2. by the compound preparation become prepared by the poultry compound medicine described in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610704773.7A CN106109638A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and LIJUNJING |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610704773.7A CN106109638A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and LIJUNJING |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106109638A true CN106109638A (en) | 2016-11-16 |
Family
ID=57274079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610704773.7A Withdrawn CN106109638A (en) | 2016-08-22 | 2016-08-22 | A kind of poultry compound medicine containing Fructus Rosae Laevigatae and LIJUNJING |
Country Status (1)
| Country | Link |
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| CN (1) | CN106109638A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728479A (en) * | 2016-12-16 | 2017-05-31 | 范明忠 | A kind of livestock and poultry compound medicine containing treebine stem and LIJUNJING |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989727A (en) * | 2014-05-28 | 2014-08-20 | 广西大学 | Acalypha australis L. and mequindox containing compound medicine for livestock and poultry |
-
2016
- 2016-08-22 CN CN201610704773.7A patent/CN106109638A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989727A (en) * | 2014-05-28 | 2014-08-20 | 广西大学 | Acalypha australis L. and mequindox containing compound medicine for livestock and poultry |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106728479A (en) * | 2016-12-16 | 2017-05-31 | 范明忠 | A kind of livestock and poultry compound medicine containing treebine stem and LIJUNJING |
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| C06 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20161116 |