CN106029623A - 用于从微生物细胞获得微生物油的方法 - Google Patents

用于从微生物细胞获得微生物油的方法 Download PDF

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Publication number
CN106029623A
CN106029623A CN201480075851.0A CN201480075851A CN106029623A CN 106029623 A CN106029623 A CN 106029623A CN 201480075851 A CN201480075851 A CN 201480075851A CN 106029623 A CN106029623 A CN 106029623A
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China
Prior art keywords
oil
aforementioned
acid
cell
microbial
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Pending
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CN201480075851.0A
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English (en)
Chinese (zh)
Inventor
N·F·莱宁格尔
G·尚克
X·董
J·W·普法伊费尔三世
V·派
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DSM IP Assets BV
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DSM IP Assets BV
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Priority to CN202310049763.4A priority Critical patent/CN116254148A/zh
Publication of CN106029623A publication Critical patent/CN106029623A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/02—Pretreatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/02—Pretreatment
    • C11B1/025—Pretreatment by enzymes or microorganisms, living or dead
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/001—Refining fats or fatty oils by a combination of two or more of the means hereafter
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C12N1/066—Lysis of microorganisms by physical methods

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201480075851.0A 2013-12-20 2014-12-19 用于从微生物细胞获得微生物油的方法 Pending CN106029623A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310049763.4A CN116254148A (zh) 2013-12-20 2014-12-19 用于从微生物细胞获得微生物油的方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361919000P 2013-12-20 2013-12-20
US61/919,000 2013-12-20
US201462093986P 2014-12-18 2014-12-18
US62/093,986 2014-12-18
PCT/US2014/071469 WO2015095696A1 (en) 2013-12-20 2014-12-19 Processes for obtaining microbial oil from microbial cells

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202310049763.4A Division CN116254148A (zh) 2013-12-20 2014-12-19 用于从微生物细胞获得微生物油的方法

Publications (1)

Publication Number Publication Date
CN106029623A true CN106029623A (zh) 2016-10-12

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CN202310049763.4A Pending CN116254148A (zh) 2013-12-20 2014-12-19 用于从微生物细胞获得微生物油的方法

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US (3) US20160319218A1 (enExample)
EP (1) EP3083546B1 (enExample)
JP (2) JP2017500041A (enExample)
KR (1) KR102435265B1 (enExample)
CN (2) CN106029623A (enExample)
AU (1) AU2014369048B2 (enExample)
BR (1) BR112016014518B1 (enExample)
CA (1) CA2934509C (enExample)
ES (1) ES2909791T3 (enExample)
IL (1) IL246333B (enExample)
MX (1) MX388703B (enExample)
NZ (1) NZ721409A (enExample)
PL (1) PL3083546T3 (enExample)
SG (1) SG11201605066WA (enExample)
TW (1) TWI646189B (enExample)
WO (1) WO2015095696A1 (enExample)

Cited By (6)

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CN110462014A (zh) * 2016-12-27 2019-11-15 赢创德固赛有限公司 从含有脂质的生物质中分离脂质的方法
WO2020038295A1 (zh) * 2018-08-20 2020-02-27 梁云 在线加热分离微生物油脂的装置和方法以及微生物油脂
CN111492062A (zh) * 2017-12-20 2020-08-04 赢创运营有限公司 从含有脂质的生物质中分离脂质的方法
CN112166176A (zh) * 2018-05-15 2021-01-01 赢创运营有限公司 借助疏水性二氧化硅从含有脂质的生物质中分离脂质的方法
CN113544244A (zh) * 2019-03-14 2021-10-22 帝斯曼知识产权资产管理有限公司 通过酶和ph冲击从微生物细胞组合物中获得脂质的方法
CN113574045A (zh) * 2019-03-14 2021-10-29 帝斯曼知识产权资产管理有限公司 从微生物细胞组合物中获得脂质的方法

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JP5911479B2 (ja) 2010-06-01 2016-04-27 ディーエスエム アイピー アセッツ ビー．ブイ． 細胞からの脂質の抽出およびそれに由来する生産物
WO2015095690A2 (en) 2013-12-20 2015-06-25 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
JP6705581B2 (ja) 2013-12-20 2020-06-03 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 微生物細胞から微生物油を入手するための方法
CA2934490C (en) 2013-12-20 2022-05-03 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
CA2934506C (en) 2013-12-20 2022-05-03 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
NZ721409A (en) 2013-12-20 2022-10-28 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
JP6738214B2 (ja) * 2016-06-17 2020-08-12 アースリサイクル株式会社 バイオ燃料の製造方法
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AU2017297752B2 (en) * 2016-07-13 2021-09-23 Dsm Ip Assets B.V. Method for isolating lipids from lipid-containing cells
DK201970085A1 (en) * 2016-07-13 2019-02-21 Dsm Ip Assets B.V. Method for isolating lipids from lipid-containing cells
US11946017B2 (en) 2016-07-13 2024-04-02 Evonik Operations Gmbh Method of separating lipids from a lysed lipids containing biomass
IL247522A0 (en) * 2016-08-29 2016-11-30 Technion Res & Dev Foundation Removal of pollutants from organic matter
BR112020003326A2 (pt) 2017-08-17 2020-11-17 Evonik Operations Gmbh produção acentuada de lipídios pela limitação de pelo menos duas fontes de nutrientes limitantes
EA202090440A1 (ru) 2017-09-21 2020-07-17 Эвоник Оперейшенс ГмбХ Улучшенное получение липидов путем ограничения по меньшей мере двух источников лимитирующих питательных веществ
CN111601872A (zh) * 2017-12-22 2020-08-28 帝斯曼知识产权资产管理有限公司 包含至少一种具有至少20个碳原子的多不饱和脂肪酸(lc-pufa)的油
EP3775118A4 (en) * 2018-03-30 2022-03-09 DSM IP Assets B.V. Method of reducing emulsion by broth washing
WO2019219396A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
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FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
FR3111912B1 (fr) 2020-06-24 2025-10-03 Fermentalg Procédé de culture de microorganismes pour l’accumulation de lipides
WO2023135584A1 (en) * 2022-01-17 2023-07-20 Phycoil Biotechnology International, Inc. Novel thraustochytrid strain for the production of biomaterials including long-chain polyunsaturated fatty acids
CN115786412A (zh) * 2022-11-22 2023-03-14 嘉必优生物技术（武汉）股份有限公司 一种多不饱和脂肪酸油脂的提取方法

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