CN1060293A - 血纤维蛋白原受体拮抗剂 - Google Patents
血纤维蛋白原受体拮抗剂 Download PDFInfo
- Publication number
- CN1060293A CN1060293A CN91109394A CN91109394A CN1060293A CN 1060293 A CN1060293 A CN 1060293A CN 91109394 A CN91109394 A CN 91109394A CN 91109394 A CN91109394 A CN 91109394A CN 1060293 A CN1060293 A CN 1060293A
- Authority
- CN
- China
- Prior art keywords
- thrombocyte
- mammals
- composition
- gets
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58928290A | 1990-09-27 | 1990-09-27 | |
US589,282 | 1990-09-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1060293A true CN1060293A (zh) | 1992-04-15 |
Family
ID=24357362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN91109394A Pending CN1060293A (zh) | 1990-09-27 | 1991-09-26 | 血纤维蛋白原受体拮抗剂 |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0479481A3 (fi) |
JP (1) | JPH0517498A (fi) |
KR (1) | KR920006373A (fi) |
CN (1) | CN1060293A (fi) |
AU (1) | AU8477891A (fi) |
CA (1) | CA2052057A1 (fi) |
CS (1) | CS294791A3 (fi) |
FI (1) | FI914532A (fi) |
HU (1) | HUT60751A (fi) |
IE (1) | IE913380A1 (fi) |
IL (1) | IL99539A0 (fi) |
MX (1) | MX9101311A (fi) |
NO (1) | NO913786L (fi) |
PT (1) | PT99095A (fi) |
ZA (1) | ZA917695B (fi) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU666318B2 (en) * | 1991-06-28 | 1996-02-08 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
US5939412A (en) * | 1992-06-26 | 1999-08-17 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
US5340798A (en) * | 1992-10-14 | 1994-08-23 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
EP0667773A4 (en) * | 1992-10-14 | 1996-09-25 | Merck & Co Inc | FIBRINOGEN RECEPTOR ANTAGONISTS. |
US5358956A (en) * | 1992-10-14 | 1994-10-25 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
EP0664792B1 (en) * | 1992-10-14 | 2000-01-05 | Merck & Co. Inc. | Fibrinogen receptor antagonists |
CA2150550A1 (en) * | 1992-12-01 | 1994-06-09 | Melissa S. Egbertson | Fibrinogen receptor antagonists |
NZ262942A (en) * | 1993-03-29 | 1997-07-27 | Zeneca Ltd | Pyridyl substituted piperazine and various other derivatives of azaheteroaryl substituted piperazines; pharmaceutical compositions |
US5652242A (en) * | 1993-03-29 | 1997-07-29 | Zeneca Limited | Heterocyclic derivatives |
SK120895A3 (en) * | 1993-03-29 | 1996-06-05 | Zeneca Ltd | Pyridine derivatives, process for preparing the same and intermediate products in this process and pharmaceutical compositions containing them |
US5753659A (en) * | 1993-03-29 | 1998-05-19 | Zeneca Limited | Heterocyclic compouds |
US5750754A (en) * | 1993-03-29 | 1998-05-12 | Zeneca Limited | Heterocyclic compounds |
US5334596A (en) * | 1993-05-11 | 1994-08-02 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5463011A (en) * | 1993-06-28 | 1995-10-31 | Zeneca Limited | Acid derivatives |
GB9313285D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Acid derivatives |
GB9313268D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Chemical compounds |
US5397791A (en) * | 1993-08-09 | 1995-03-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US6274705B1 (en) | 1996-05-02 | 2001-08-14 | Aventis Pharmaceuticals Products Inc. | Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides |
DK0812205T3 (da) * | 1993-10-15 | 2001-04-17 | Rhone Poulenc Rorer Pharma | Antithrombotiske azacycloalkylalkanoylpeptider og -pseudopeptider |
US5780590A (en) * | 1993-10-15 | 1998-07-14 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides |
MA23420A1 (fr) * | 1994-01-07 | 1995-10-01 | Smithkline Beecham Corp | Antagonistes bicycliques de fibrinogene. |
US6458784B1 (en) | 1994-06-29 | 2002-10-01 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
US5451578A (en) * | 1994-08-12 | 1995-09-19 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5525617A (en) * | 1994-08-24 | 1996-06-11 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
US5789421A (en) * | 1995-10-26 | 1998-08-04 | Merck & Co., Inc. | Fibrinogen receptor antagonist |
US5780480A (en) * | 1996-02-28 | 1998-07-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
AP1390A (en) * | 1996-11-27 | 2005-04-15 | Aventis Pharmaceuticals Products Inc | Pharmaceutical composition comprising a compound having anti-Xa activity and a platelet aggregation antagonist compound. |
EP1747219A4 (en) * | 2004-05-13 | 2010-05-26 | Glaxo Group Ltd | Antagonists of muscarinic acetylcholine receptor |
-
1991
- 1991-09-20 IL IL99539A patent/IL99539A0/xx unknown
- 1991-09-23 CA CA002052057A patent/CA2052057A1/en not_active Abandoned
- 1991-09-25 EP EP19910308722 patent/EP0479481A3/en not_active Withdrawn
- 1991-09-26 HU HU913074A patent/HUT60751A/hu unknown
- 1991-09-26 NO NO91913786A patent/NO913786L/no unknown
- 1991-09-26 KR KR1019910016759A patent/KR920006373A/ko not_active Application Discontinuation
- 1991-09-26 PT PT99095A patent/PT99095A/pt not_active Application Discontinuation
- 1991-09-26 ZA ZA917695A patent/ZA917695B/xx unknown
- 1991-09-26 CN CN91109394A patent/CN1060293A/zh active Pending
- 1991-09-26 CS CS912947A patent/CS294791A3/cs unknown
- 1991-09-26 FI FI914532A patent/FI914532A/fi not_active Application Discontinuation
- 1991-09-26 IE IE338091A patent/IE913380A1/en unknown
- 1991-09-26 AU AU84778/91A patent/AU8477891A/en not_active Abandoned
- 1991-09-27 MX MX9101311A patent/MX9101311A/es unknown
- 1991-09-27 JP JP3248809A patent/JPH0517498A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ZA917695B (en) | 1992-05-27 |
FI914532A (fi) | 1992-03-28 |
JPH0517498A (ja) | 1993-01-26 |
EP0479481A2 (en) | 1992-04-08 |
IL99539A0 (en) | 1992-08-18 |
NO913786L (no) | 1992-03-30 |
NO913786D0 (no) | 1991-09-26 |
IE913380A1 (en) | 1992-04-08 |
PT99095A (pt) | 1992-08-31 |
MX9101311A (es) | 1992-05-04 |
EP0479481A3 (en) | 1993-07-28 |
CS294791A3 (en) | 1992-04-15 |
HUT60751A (en) | 1992-10-28 |
FI914532A0 (fi) | 1991-09-26 |
HU913074D0 (en) | 1992-01-28 |
AU8477891A (en) | 1992-04-02 |
KR920006373A (ko) | 1992-04-27 |
CA2052057A1 (en) | 1992-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C01 | Deemed withdrawal of patent application (patent law 1993) | ||
WD01 | Invention patent application deemed withdrawn after publication |