CN105998283A - Traditional Chinese medicinal lotion for treatment of papular type urticaria and preparation method thereof - Google Patents
Traditional Chinese medicinal lotion for treatment of papular type urticaria and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A61K31/125—Camphor; Nuclear substituted derivatives thereof
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention relates to a traditional Chinese medicinal lotion for treatment of papular type urticaria and a preparation method thereof. The lotion comprises the following raw materials by weight: 10-20 parts of mint, 10-20 parts of camphor, 20-40 parts of radix sophorae flavescentis, 10-20 parts of Schizonepeta, 10-20 parts of Saposhnikovia divaricata, 10-20 parts of purslane, 10-20 parts of beef-steak plant leaf, 10-20 parts of dried tangerine or orange peel, 10-20 parts of the root of kudzu vine and 10-20 parts of licorice. The preparation method is as below: crushing all raw materials into traditional Chinese medicine granules; filling a glass container with the granules, adding alcohol, mixing, conducting ultrasonic treatment, sealing the lid of the glass container, and soaking to obtain a mixture; filtrating the soaked mixture to obtain a filtrate and filter residues; adding ethanol into the filter residues, centrifuging, taking a supernatant, and mixing the supernatant with the filtrate to obtain a traditional Chinese traditional medicinal extract; and concentrating the traditional Chinese medicine extract to obtain the traditional Chinese medicinal lotion for treatment of papular type urticaria. The traditional Chinese medicinal lotion has obvious curative effect on papular type urticaria, and has the characteristics of good curative effect, little side effect, and no recurrence.
Description
Technical field
The present invention relates to traditional Chinese medicine field, especially relate to a kind of Chinese medicinal pigmentum treating papular urticaria and preparation method thereof.
Background technology
Papular urticaria is also known as lichen urticatus, strophulus.Being infant and the common anaphylaxis dermatosis of child, adult also can suffer from that this is sick, is mainly in season in spring and autumn.Great majority morbidity is the most relevant with sting, the anaphylaxis caused after biting such as mosquito, Cimex bedbug, flea, louse, demodicid mite, midge etc..Skin lesion is mainly in trunk, and extremity stretch side, cluster or be dispersed in.For the most fusiform red welt sample infringement of Semen phaseoli radiati to Semen arachidis hypogaeae size, often there is phlysis on top, becomes the big vesicle of tonicity into hemispherical protuberance after some generations soon, and content is clear, around without blush.In skin-color or pale red or filbert, some erythra are the harder big pimple of chestnut grain, in welt sample enlargement after scratching.New and old erythra exists the most simultaneously.General young children is red and swollen notable, and has bulla, often has play to itch and affect sleep.Scratch and can cause secondary infection.
Western medical treatment papular urticaria, whole body therapeutic antihistaminic how for oral administration, take the circumstances into consideration added with antibiotic with the infected；Many externals corticosteroid hormone is treated in local, available the most mould if any infecting
Element ointment, impetigo paste, Mupirocin Ointment, 0.02 furacillin solution etc..This type of Western medicine side effect is big, easily makes body develop immunity to drugs, and easily recurs, and particularly with child, the medication of Western medicine more needs with caution.
Chinese traditional treatment papular urticaria, has plurality of Chinese formula, but most formula all uses a large amount of wind dispelling insecticide to dissipate evil Chinese medicine, and the survival dose regulating the flow of vital energy scattered blood is less, although so can reach therapeutic effect, but can not reach to nurse one's health the purpose of patient body situation comprehensively.Some formula select a large amount of Chinese medicine the most of the same race, wherein have most unnecessary, can not give full play to its effect, increase drug cost on the contrary, and some Chinese medicine is rare medicinal herbs in addition, causes treatment cost substantially to increase.
Summary of the invention
For the present situation of papular urticaria treatment, it is an object of the invention to provide the Chinese medicinal pigmentum of the little treatment papular urticaria of a kind of effective, side effect.
The present invention relates to a kind of Chinese medicinal pigmentum treating papular urticaria, its each crude drug and parts by weight are: Herba Menthae 10-20 part, Camphora 10-20 part, Radix Sophorae Flavescentis 20-40 part, Herba Schizonepetae 10-20 part, Radix Saposhnikoviae 10-20 part, Herba Portulacae 10-20 part, Folium Perillae 10-20 part, Pericarpium Citri Reticulatae 10-20 part, Radix Puerariae 10-20 part and Radix Glycyrrhizae 10-20 part.
Further, a kind of Chinese medicinal pigmentum treating papular urticaria, it is characterised in that: its each crude drug and parts by weight are: Herba Menthae 15 parts, Camphora 15 parts, Radix Sophorae Flavescentis 30 parts, Herba Schizonepetae 15 parts, Radix Saposhnikoviae 15 parts, Herba Portulacae 15 parts, Folium Perillae 15 parts, Pericarpium Citri Reticulatae 15 parts, Radix Puerariae 15 parts and 15 parts of Radix Glycyrrhizae.
Further, the preparation method of a kind of Chinese medicinal pigmentum treating papular urticaria that the present invention relates to, comprise the following steps:
Step one, take Herba Menthae, Camphora, Radix Sophorae Flavescentis, Herba Schizonepetae, Radix Saposhnikoviae, Herba Portulacae, Folium Perillae, Pericarpium Citri Reticulatae, Radix Puerariae and Radix Glycyrrhizae respectively according to the parts by weight of each crude drug in the Chinese medicinal pigmentum for the treatment of papular urticaria, the Chinese medicinal granule of 100-200 mesh it is ground into after mixing, standby；
Step 2, step one gained Chinese medicinal granule is loaded in glass container, add 3-4 times of Chinese medicinal granule quality and volumetric concentration is the ethanol water of 75-95%, mixing, supersound process 20-40min is carried out under frequency 15-30kHz, glass container is covered, soak 3-5 days, mixture after being soaked, standby；
Step 3, by step 2 gained soak after mixture filter, obtain filtrate and filtering residue；In filtering residue, add 1-2 times of its quality and volumetric concentration is 75-95% ethanol water, after mixing, centrifugation, obtain supernatant；Gained supernatant is mixed with filtrate, obtains Chinese medicine extraction liquid, be placed in glass container, standby；
Step 4, glass container equipped with Chinese medicine extraction liquid described in step 3 is placed in 20-30min in the water-bath of 50-60 DEG C, is cooled to room temperature, i.e. prepares the Chinese medicinal pigmentum for the treatment of papular urticaria.
Further, the Chinese medicinal pigmentum of described treatment papular urticaria is tincture.
Depending on the using method of Chinese medicinal pigmentum of the present invention and consumption are according to factors such as age of patient, health, symptom weights, preferred as one: to dip tincture with disinfecting cotton swab and be applied at erythra, every day 3-4 time, can suitably be decreased or increased, according to the weight of symptom, the number of times smeared.It within one week, it is a course for the treatment of.
Beneficial effect:
1, the Radix Sophorae Flavescentis in the present invention and Radix Saposhnikoviae, has heat clearing and damp drying, the merit of wind dispelling insecticide；Herba Menthae, Herba Schizonepetae, have dispel the wind, antipruritic, rash, the effect of antiinflammatory；Camphora can detoxify keep away dirty, reducing swelling and alleviating pain, have slight local anesthesia effect；Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, it is possible to cushion toxicity, strong, it is in harmonious proportion hundred medicines；Pericarpium Citri Reticulatae and Herba Portulacae heat-clearing and toxic substances removing, dissipate blood detumescence；Folium Perillae can be delivered, cold expelling, regulate the flow of vital energy and seek；Radix Puerariae can dismiss positive bright epidemic febrile disease pathogenic heat.The mutual synergism of each medicine in the present invention, utilize Radix Sophorae Flavescentis and Radix Saposhnikoviae heat clearing and damp drying, Herba Schizonepetae and Radix Puerariae is antipruritic, rash and antiinflammatory, the clear Tianjin pain relieving of Radix Saposhnikoviae, Herba Menthae and Camphora, Pericarpium Citri Reticulatae and Herba Portulacae dissipate blood detumescence simultaneously, last Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, play altogether scattered wind, invigorate blood circulation, dehumidify, antipruritic merit, papular urticaria there is significant curative effect, cure rate reaches 98.67%, and cure rate reaches 78.67% in the course for the treatment of, have good effect, be easily accepted by, side effect is little, safety is easy, low cost and be difficult to recurrence feature.
2, in the preparation process of the Chinese medicinal pigmentum for the treatment of papular urticaria of the present invention, the leaching of the impurity such as phlegmatic temperament in medical material, starch, protein can be reduced with ethanol extraction.The solubility property of ethanol between polarity and nonpolar between, some composition water miscible can be dissolved, some compositions that non-polar solven is dissolved can be dissolved again.Ethanol has pharmacological action simultaneously.But concentration of alcohol is too high is difficult to remove water colo(u)r, resin etc., too low being difficult to removes polysaccharide, protein and inorganic salts impurity.So using the ethanol of 75-95% concentration as the solvent of crude drug, effective ingredient can be made to separate out to a greater degree, improving the therapeutic effect that the present invention treats the Chinese medicinal pigmentum of papular urticaria.
3, in the preparation process of the Chinese medicinal pigmentum for the treatment of papular urticaria of the present invention, crude drug is broken into coarse granule, further crush with ultrasound wave, in the process, utilize the special roles such as the sharp pounding that ultrasound wave produces, high acceleration, strong cavitation effect, stirring, the cell of vegetable drug can be destroyed, it is in the cell that solvent penetrates into medical material, to make the chemical composition in medical material be dissolved in solvent, it is greatly improved the therapeutic effect that the present invention treats the Chinese medicinal pigmentum of papular urticaria, hence it is evident that shorten treatment cycle.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further illustrated.
Embodiment 1: a kind of Chinese medicinal pigmentum treating papular urticaria, its preparation comprises the following steps:
Step one, take Herba Menthae 10g, Camphora 15g, Radix Sophorae Flavescentis 20g, Herba Schizonepetae 15g, Radix Saposhnikoviae 15g, Herba Portulacae 10g, Folium Perillae 20g, Pericarpium Citri Reticulatae 10g, Radix Puerariae 10g and Radix Glycyrrhizae 10g, after mixing, be ground into the Chinese medicinal granule of 100-200 mesh, standby；
Step 2, the Chinese medicinal granule of step one gained is loaded in vial, add 75% ethanol 400ml, mixing, use 15kHz ultrasonic echography to process 20min, vial is covered, soaks 3 days, mixture after being soaked, standby；
Step 3, by step 2 gained soak after the mixture gauze of 500 mesh filter, obtain filtrate and filtering residue；In filtering residue, add 75% ethanol 100ml, 200g centrifugation 2min, take supernatant；Gained supernatant is mixed with filtrate, obtains Chinese medicine extraction liquid, be placed in glass container, standby；
Step 4, glass container equipped with Chinese medicine extraction liquid described in step 3 is placed in 20min in the water-bath of 55 DEG C, is cooled to room temperature, the Chinese medicinal pigmentum of papular urticaria must be treated.
Embodiment 2: a kind of Chinese medicinal pigmentum treating papular urticaria, its preparation comprises the following steps:
Step one, take Herba Menthae 15g, Camphora 15g, Radix Sophorae Flavescentis 30g, Herba Schizonepetae 15g, Radix Saposhnikoviae 15g, Herba Portulacae 15g, Folium Perillae 15g, Pericarpium Citri Reticulatae 15g, Radix Puerariae 15g and Radix Glycyrrhizae 15g, after mixing, be ground into the Chinese medicinal granule of 100-200 mesh, standby；
Step 2, the Chinese medicinal granule of step one gained is loaded in vial, add 95% ethanol 400ml, mixing, use 20kHz ultrasonic echography to process 20min, vial is covered, soaks 3 days, mixture after being soaked, standby；
Step 3, by step 2 gained soak after the mixture gauze of 500 mesh filter, obtain filtrate and filtering residue；In filtering residue, add 95% ethanol 100ml, 200g centrifugation 2min, take supernatant；Gained supernatant is mixed with filtrate, obtains Chinese medicine extraction liquid, be placed in glass container, standby；
Step 4, glass container equipped with Chinese medicine extraction liquid described in step 3 is placed in 30min in the water-bath of 55 DEG C, is cooled to room temperature, the Chinese medicinal pigmentum of papular urticaria must be treated.
Embodiment 3: a kind of Chinese medicinal pigmentum treating papular urticaria, its preparation comprises the following steps:
Step one, take Herba Menthae 15g, Camphora 20g, Radix Sophorae Flavescentis 35g, Herba Schizonepetae 20g, Radix Saposhnikoviae 20g, Herba Portulacae 10g, Folium Perillae 15g, Pericarpium Citri Reticulatae 20g, Radix Puerariae 10g and Radix Glycyrrhizae 10g, after mixing, be ground into the Chinese medicinal granule of 100-200 mesh, standby；
Step 2, the Chinese medicinal granule of step one gained is loaded in vial, add 80% ethanol 450ml, mixing, use 25kHz ultrasonic echography to process 30min, vial is covered, soaks 4 days, mixture after being soaked, standby；
Step 3, by step 2 gained soak after the mixture gauze of 500 mesh filter, obtain filtrate and filtering residue；In filtering residue, add 80% ethanol 150ml, 200g centrifugation 2min, take supernatant；Gained supernatant is mixed with filtrate, obtains Chinese medicine extraction liquid, be placed in glass container, standby；
Step 4, glass container equipped with Chinese medicine extraction liquid described in step 3 is placed in 25min in the water-bath of 50 DEG C, is cooled to room temperature, the Chinese medicinal pigmentum of papular urticaria must be treated.
Embodiment 4: a kind of Chinese medicinal pigmentum treating papular urticaria, its preparation comprises the following steps:
Step one, take Herba Menthae 20g, Camphora 10g, Radix Sophorae Flavescentis 40g, Herba Schizonepetae 10g, Radix Saposhnikoviae 10g, Herba Portulacae 20g, Folium Perillae 10g, Pericarpium Citri Reticulatae 20g, Radix Puerariae 20g and Radix Glycyrrhizae 20g, after mixing, be ground into the Chinese medicinal granule of 100-200 mesh, standby；
Step 2, the Chinese medicinal granule of step one gained is loaded in vial, add 85% ethanol 600ml, mixing, use 30kHz ultrasonic echography to process 25min, vial is covered, soaks 5 days, mixture after being soaked, standby；
Step 3, by step 2 gained soak after the mixture gauze of 500 mesh filter, obtain filtrate and filtering residue；In filtering residue, add 85% ethanol 200ml, 200g centrifugation 2min, take supernatant；Gained supernatant is mixed with filtrate, obtains Chinese medicine extraction liquid, be placed in glass container, standby；
Step 4, glass container equipped with Chinese medicine extraction liquid described in step 3 is placed in 20min in the water-bath of 60 DEG C, is cooled to room temperature, the Chinese medicinal pigmentum of papular urticaria must be treated.
Clinical observation:
1. Therapeutic Method: dip tincture with disinfecting cotton swab and be applied at erythra, every day 3-4 time, can suitably be decreased or increased, according to the weight of symptom, the number of times smeared.It within one week, it is a course for the treatment of.
2. treatment evaluation criterion: recovery from illness: pruritus disappears, deflorescence, without recurrence in 1 year.Effective: pruritus disappears, deflorescence had recurrence in 1 year.Invalid: pruritus is more than, newly sends out skin lesion.
3. therapeutic effect: 75 examples are through treatment, 70 examples of fully recovering (93.33%), effective 4 examples (5.33%), invalid 1 example (1.33%).59 examples of fully recovering one of them course for the treatment of (78.67%), 14 examples (18.67%) of fully recovering 2-3 the course for the treatment of, 1 example (1.33%) of fully recovering 4 courses for the treatment of.
4. clinical model case:
Clinical case 1: poplar, female, 2 years old, head extremity went out the little rash of red globular shape, very itch, and alleviated, transference cure after 1 week after coating.Further consultation after 3 weeks, pruritus disappears, deflorescence.Follow up a case by regular visits to after drug withdrawal 1 year have no recurrence.
Clinical case 2: Wang, female, 12 years old, extremity went out red little rash, very itch, and alleviated, transference cure after 1 week after coating.Further consultation after 3 weeks, pruritus disappears, deflorescence.Follow up a case by regular visits to after drug withdrawal 1 year have no recurrence.
Clinical case 3: Tan, man, 11 years old, the red welt sample pimple of the existing Semen phaseoli radiati of waist to Semen arachidis hypogaeae size, there was phlysis on top, and pruritus unbearably, after coating, alleviated by symptom, adheres to coating 1 week, and pruritus disappears, and erythra forms a scab.Further consultation after 3 weeks, pruritus disappears, deflorescence.Follow up a case by regular visits to after drug withdrawal 1 year have no recurrence.
Claims (3)
1. the Chinese medicinal pigmentum treating papular urticaria, it is characterized in that: its each crude drug and parts by weight are: Herba Menthae 10-20 part, Camphora 10-20 part, Radix Sophorae Flavescentis 20-40 part, Herba Schizonepetae 10-20 part, Radix Saposhnikoviae 10-20 part, Herba Portulacae 10-20 part, Folium Perillae 10-20 part, Pericarpium Citri Reticulatae 10-20 part, Radix Puerariae 10-20 part and Radix Glycyrrhizae 10-20 part.
A kind of Chinese medicinal pigmentum treating papular urticaria, it is characterised in that: its each crude drug and parts by weight are: Herba Menthae 15 parts, Camphora 15 parts, Radix Sophorae Flavescentis 30 parts, Herba Schizonepetae 15 parts, Radix Saposhnikoviae 15 parts, Herba Portulacae 15 parts, Folium Perillae 15 parts, Pericarpium Citri Reticulatae 15 parts, Radix Puerariae 15 parts and 15 parts of Radix Glycyrrhizae.
A kind of preparation method of the Chinese medicinal pigmentum treating papular urticaria, it is characterised in that: comprise the following steps:
Step one, take Herba Menthae, Camphora, Radix Sophorae Flavescentis, Herba Schizonepetae, Radix Saposhnikoviae, Herba Portulacae, Folium Perillae, Pericarpium Citri Reticulatae, Radix Puerariae and Radix Glycyrrhizae respectively according to the parts by weight of each crude drug in the Chinese medicinal pigmentum for the treatment of papular urticaria, the Chinese medicinal granule of 100-200 mesh it is ground into after mixing, standby；
Step 2, step one gained Chinese medicinal granule is loaded in glass container, add 3-4 times of Chinese medicinal granule quality and volumetric concentration is the ethanol water of 75-95%, mixing, supersound process 20-40min is carried out under frequency 15-30kHz, glass container is covered, soak 3-5 days, mixture after being soaked, standby；
Step 3, by step 2 gained soak after mixture filter, obtain filtrate and filtering residue；In filtering residue, add 1-2 times of its quality and volumetric concentration is 75-95% ethanol water, after mixing, centrifugation, obtain supernatant；Gained supernatant is mixed with filtrate, obtains Chinese medicine extraction liquid, be placed in glass container, standby；
Step 4, glass container equipped with Chinese medicine extraction liquid described in step 3 is placed in 20-30min in the water-bath of 50-60 DEG C, is cooled to room temperature, i.e. prepares the Chinese medicinal pigmentum for the treatment of papular urticaria.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631647A (en) * | 2012-03-23 | 2012-08-15 | 王莲芬 | Chinese patent medicine mixture for treating acute urticaria |
| CN104258181A (en) * | 2014-09-22 | 2015-01-07 | 彭阳 | Traditional Chinese medicine preparation for treating acute urticaria |
| CN105287717A (en) * | 2015-12-07 | 2016-02-03 | 广东伊茗药业有限公司 | Externally applied preparation composition for treating mosquito bites and insect bites and preparation method of external preparation composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631647A (en) * | 2012-03-23 | 2012-08-15 | 王莲芬 | Chinese patent medicine mixture for treating acute urticaria |
| CN104258181A (en) * | 2014-09-22 | 2015-01-07 | 彭阳 | Traditional Chinese medicine preparation for treating acute urticaria |
| CN105287717A (en) * | 2015-12-07 | 2016-02-03 | 广东伊茗药业有限公司 | Externally applied preparation composition for treating mosquito bites and insect bites and preparation method of external preparation composition |
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