CN105148074A - Medicinal preparation used for treating diabetes - Google Patents
Medicinal preparation used for treating diabetes Download PDFInfo
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- CN105148074A CN105148074A CN201510637967.5A CN201510637967A CN105148074A CN 105148074 A CN105148074 A CN 105148074A CN 201510637967 A CN201510637967 A CN 201510637967A CN 105148074 A CN105148074 A CN 105148074A
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Abstract
The invention belongs to the field of Chinese herb preparations, and particularly provides a medicinal preparation used for treating diabetes. The medicinal preparation is prepared from 28 parts of grangea maderaspatana, 20 parts of abelia chinensis, 25 parts of bodinier caper, 20 parts of bergenia purpurascens, 18 parts of alisma plantago-aquatica, 20 parts of scrophularia ningpoensis, 25 parts of radix astragali, 25 parts of angelica sinensis, 20 parts of cinnamomum cassia, 20 parts of radix trichosanthis, 20 parts of radix rehmanniae, 25 parts of dogwood, 20 parts of dandelions, 15 parts of prunella vulgaris, 15 parts of chrysanthemums and 5 parts of glycyrrhiza uralensis. The medicinal preparation is capable of treating diabetes.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of diabetes and its preparation method and application.
Background technology
The metabolic disease of diabetes to be one group with hyperglycemia be feature.Hyperglycemia be then due to defect of insulin secretion or its biological agent impaired, or both have concurrently and cause.Long-standing hyperglycemia during diabetes, causes various tissue, particularly eye, kidney, heart, blood vessel, neural chronic lesion, dysfunction.For this reason, be bursting to and develop the needs that more medicines for the treatment of diabetes safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of diabetes conditions.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of diabetes, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Polygalae lateriflorae 28 parts, Abelia Chinensis R. Br. 20 parts, Cortex capparis Bodinieri radicis 25 parts, yellow hair Rhizoma Seu Herba Bergeniae 20 parts, Rhizoma Alismatis 18 parts, Radix Scrophulariae 20 parts, the Radix Astragali 25 parts, Radix Angelicae Sinensis 25 parts, Cortex Cinnamomi 20 parts, Radix Trichosanthis 20 parts, 20 parts, the Radix Rehmanniae, Fructus Corni 25 parts, Herba Taraxaci 20 parts, Spica Prunellae 15 parts, Flos Chrysanthemi 15 parts, 5 parts, Radix Glycyrrhizae.
The described pharmaceutical preparation being used for the treatment of diabetes, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of diabetes, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of pharmaceutical preparation in preparation treatment diabetes medicament being used for the treatment of diabetes.
Herba Polygalae lateriflorae is the herb of milk wort side raw flower Radix Polygalae.Heat-clearing and toxic substances removing, YIN nourishing arresting sweating, synthetism.Control night sweat, fracture.
Abelia Chinensis R. Br. is Caprifoliaceae, Abelia.Latin is called AbeliachinensisR.Br., produces East China, Central-South and southwest.Stem, leaf, herb: heat-clearing and toxic substances removing, hemostasis.For having loose bowels, children's's infantile malnutrition worm-eaten tooth, traumatic injury, influenza.Oral aphthae in children is controlled in external, parotitis.The present invention is with all herbal medicine.
Cortex capparis Bodinieri radicis is the Herb of osmanthus, Capparidaceae plant Guizhou Province Capparis Spirrosa: relaxing muscles and tendons and activating QI and blood in the collateral, heat-clearing and toxic substances removing.Herb: for rheumatalgia, traumatic injury; Root bark: tonsillitis, toothache.
Yellow hair Rhizoma Seu Herba Bergeniae is Yunnan, Gesneriaceae horse bell lettuce carex river horse bell lettuce tongue OreocharishenryanaOliv., with all herbal medicine.Xia Qiu gathers, and dries.Energy clearing away lung-heat to relieve cough, relievings asthma, hemostasis.For epersalgia cough, asthma, spits blood.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: the category that diabetes spp is quenched one's thirst in the traditional Chinese medical science.Quenching one's thirst is a kind of disease that is feature with polydipsia, polyphagia, polyuria, lean body mass.The traditional Chinese medical science is thought, eating and drinking without temperance, disorder of emotion, labor all can cause quenching one's thirst for the factor such as excessive, ferritic is weak.Herba Polygalae lateriflorae of the present invention, Abelia Chinensis R. Br., Cortex capparis Bodinieri radicis, yellow hair Rhizoma Seu Herba Bergeniae, Rhizoma Alismatis, Radix Scrophulariae, the Radix Astragali, Radix Angelicae Sinensis, Cortex Cinnamomi heat-clearing and toxic substances removing, nourishing YIN to lower pathogenic fire, invigorating the spleen for eliminating dampness are monarch drug, Radix Trichosanthis, the Radix Rehmanniae, Fructus Corni, Herba Taraxaci, Spica Prunellae, Flos Chrysanthemi blood circulation promoting and blood stasis dispelling, benefiting vital QI and blood are ministerial drug, Radix Glycyrrhizae is adjuvant, the mutual compatibility of full side, treatment diabetes successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Herba Polygalae lateriflorae 28g, Abelia Chinensis R. Br. 20g, Cortex capparis Bodinieri radicis 25g, yellow hair Rhizoma Seu Herba Bergeniae 20g, Rhizoma Alismatis 18g, Radix Scrophulariae 20g, Radix Astragali 25g, Radix Angelicae Sinensis 25g, Cortex Cinnamomi 20g, Radix Trichosanthis 20g, Radix Rehmanniae 20g, Fructus Corni 25g, Herba Taraxaci 20g, Spica Prunellae 15g, Flos Chrysanthemi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Herba Polygalae lateriflorae 28g, Abelia Chinensis R. Br. 20g, Cortex capparis Bodinieri radicis 25g, yellow hair Rhizoma Seu Herba Bergeniae 20g, Rhizoma Alismatis 18g, Radix Scrophulariae 20g, Radix Astragali 25g, Radix Angelicae Sinensis 25g, Cortex Cinnamomi 20g, Radix Trichosanthis 20g, Radix Rehmanniae 20g, Fructus Corni 25g, Herba Taraxaci 20g, Spica Prunellae 15g, Flos Chrysanthemi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Herba Polygalae lateriflorae 28g, Abelia Chinensis R. Br. 20g, Cortex capparis Bodinieri radicis 25g, yellow hair Rhizoma Seu Herba Bergeniae 20g, Rhizoma Alismatis 18g, Radix Scrophulariae 20g, Radix Astragali 25g, Radix Angelicae Sinensis 25g, Cortex Cinnamomi 20g, Radix Trichosanthis 20g, Radix Rehmanniae 20g, Fructus Corni 25g, Herba Taraxaci 20g, Spica Prunellae 15g, Flos Chrysanthemi 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, pharmaceutical preparation treatment diabetes of the present invention clinical research
4.1 general data: this pharmaceutical preparation is applied to clinical observation diabetes cases 70 example, 35 ~ 65 years old age.The shortest person of the course of disease 4 months, most elder reaches 8 years.
4.2 diagnostic criterias: (1) thirsty polydipsia, polyorexia, urinary micturition, emaciated physique; (2) from the beginning of can " more than three " symptom not work.Sick Chang Bingfa is for a long time dizzy, pulmonary tuberculosis, the thoracic obstruction, apoplexy, nyctalopia, furuncle etc.The visible excessive thirst of severe patient, headache, vomiting, stomachache, short of breath, the de-crisis even stupor is fainted; (3) empty stomach, 2 hours after the meal glucoses in urine and blood glucose, specific gravity of urine, glucose tolerance test is looked into.Have urine examined ketoboidies, blood urea nitrogen, creatinine, CO2 combining power, CO2 CP and blood potassium, sodium, calcium, chloride etc. if desired.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule one month is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: recovery from illness: transference cure, lab testing is repeatedly normal; Effective: cardinal symptom and regarding assay room check and be improved; Invalid: symptom and lab testing unchanged.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) |
Treatment group | 35 | 1 | 28 | 6 | 82.9 |
Blank group | 35 | 0 | 1 | 34 | 2.9 |
Visible, the medicine that the present invention obtains can safe and effective treatment diabetes, and have no side effect.
Claims (4)
1. one kind is used for the treatment of the pharmaceutical preparation of diabetes, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Polygalae lateriflorae 28 parts, Abelia Chinensis R. Br. 20 parts, Cortex capparis Bodinieri radicis 25 parts, yellow hair Rhizoma Seu Herba Bergeniae 20 parts, Rhizoma Alismatis 18 parts, Radix Scrophulariae 20 parts, the Radix Astragali 25 parts, Radix Angelicae Sinensis 25 parts, Cortex Cinnamomi 20 parts, Radix Trichosanthis 20 parts, 20 parts, the Radix Rehmanniae, Fructus Corni 25 parts, Herba Taraxaci 20 parts, Spica Prunellae 15 parts, Flos Chrysanthemi 15 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the pharmaceutical preparation of diabetes as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the pharmaceutical preparation of diabetes as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of pharmaceutical preparation in treatment diabetes medicament of diabetes according to claim 1.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105687555A (en) * | 2016-03-03 | 2016-06-22 | 冯字 | Pharmaceutical preparation for treating diabetes |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1616016A (en) * | 2004-09-16 | 2005-05-18 | 张永顺 | Medicine for treating diabetes and its preparing method |
CN1792374A (en) * | 2005-11-03 | 2006-06-28 | 蔡青 | Traditional Chinese medicine prepns. for treating diabete |
CN104922388A (en) * | 2015-07-17 | 2015-09-23 | 孙根火 | Medicinal preparation for treating female climacteric syndromes |
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1616016A (en) * | 2004-09-16 | 2005-05-18 | 张永顺 | Medicine for treating diabetes and its preparing method |
CN1792374A (en) * | 2005-11-03 | 2006-06-28 | 蔡青 | Traditional Chinese medicine prepns. for treating diabete |
CN104922388A (en) * | 2015-07-17 | 2015-09-23 | 孙根火 | Medicinal preparation for treating female climacteric syndromes |
Non-Patent Citations (2)
Title |
---|
李静: "滋阴益气活血组方对STZ糖尿病模型大鼠糖代谢的影响", 《动物医学进展》 * |
陈书成: "中西医结合治疗Ⅱ型糖尿病36例", 《湖北中医杂志》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105687555A (en) * | 2016-03-03 | 2016-06-22 | 冯字 | Pharmaceutical preparation for treating diabetes |
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