CN105267400A - Medicine preparation for treating gynecological vaginitis - Google Patents
Medicine preparation for treating gynecological vaginitis Download PDFInfo
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- CN105267400A CN105267400A CN201510799699.7A CN201510799699A CN105267400A CN 105267400 A CN105267400 A CN 105267400A CN 201510799699 A CN201510799699 A CN 201510799699A CN 105267400 A CN105267400 A CN 105267400A
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Abstract
The invention belongs to the field of a traditional Chinese medicine preparation, and concretely provides a medicine preparation for treating gynecological vaginitis. The medicine preparation is prepared from the following ingredients: 20 parts of anemone rivularis, 25 parts of common aeschynomene leaves, 28 parts of east Liaoning oat fruit, 26 parts of bretschneidera sinensis, 15 parts of peach kernel, 25 parts of cortex phellodendri, 28 parts of rhizome of cyrtomium, 15 parts of radix sophorae falvescentis, 15 parts of broadleaf holly leaves, 20 parts of angelica sinensis, 25 parts of herba patriniae, 20 parts of Chinese fevervine herb, 25 parts of ginkgo leaves, 20 parts of mulberry leaves, 15 parts of fructus evodiae and 5 parts of liquorice. The medicine preparation can be used for treating the gynecological vaginitis.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of gynecology colpitis and its preparation method and application.
Background technology
Female organism, due to relatively special physiological structure, easily causes women infect various antibacterial, fungus and mycete etc. thus bring out a series of diseases such as genital system infection.At present due to the restriction of technological means, the method for the treatment of female genital tract infection uses broad-spectrum antibiotic therapy usually, but this Therapeutic Method easily causes body bacterial resistance occurred, even cultivates superbacteria.And Chinese medicine can avoid Western medicine to the generation of body rough sledding, consider thus to use Chinese medicine compound to tackle this kind of infection.For this reason, be bursting to and develop the needs that more medicines for the treatment of gynecology colpitis safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of gynecology colpitis disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of gynecology colpitis, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Veronicastri Sibirici 20 parts, Folium Aeschynomenes indicae 25 parts, Fructus Querci Liaotungensis 28 parts, Cortex Bretschneiderae Sinensis 26 parts, 15 parts, Semen Persicae, Cortex Phellodendri 25 parts, Rhizoma Osmundae 28 parts, Radix Sophorae Flavescentis 15 parts, Folium Ilicis 15 parts, Radix Angelicae Sinensis 20 parts, Herba Patriniae 25 parts, Herba Paederiae 20 parts, Folium Ginkgo 25 parts, 20 parts, Folium Mori, Fructus Evodiae 15 parts, 5 parts, Radix Glycyrrhizae.
The described pharmaceutical preparation being used for the treatment of gynecology colpitis, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of gynecology colpitis, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of pharmaceutical preparation in preparation treatment gynecology colpitis medicine being used for the treatment of gynecology colpitis.
Herba Veronicastri Sibirici is Ranunculaceae thimbleweed two discrimination Anemone cathayensis Kitag. AnemonedichotomaL., is used as medicine with root stock.Autumn uproots, and dries, removing toxic substances dysentery relieving, relaxing muscles and tendons to promote blood circulation.For dysentery, furuncle carbuncle poison, traumatic injury.
Folium Aeschynomenes indicae is the leaf of leguminous plant Herba Aeschynonenes Indicae, can treat carbuncle, the diseases such as wound hemorrhage.
Fructus Querci Liaotungensis is the fruit of Fagaceae Quercus liaotungensis.Invigorating the spleen to arrest diarrhea, astringing to arrest bleeding.Control insufficiency of the spleen diarrhoea, bleeding hemorrhoids, proctoptosis.
Cortex Bretschneiderae Sinensis is the bark of Bretschneideraceae plant Bretschneidera sinensis.Control bones and muscles pain.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science thinks that gynecology colpitis belongs to the performance of damp invasion of lower energizer, Herba Veronicastri Sibirici of the present invention, Folium Aeschynomenes indicae, Fructus Querci Liaotungensis, Cortex Bretschneiderae Sinensis, Semen Persicae, Cortex Phellodendri, Rhizoma Osmundae heat-clearing and toxic substances removing, clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling are monarch drug, Radix Sophorae Flavescentis, Folium Ilicis, Radix Angelicae Sinensis, Herba Patriniae, Herba Paederiae, Folium Ginkgo, Folium Mori, Fructus Evodiae killing parasites for relieving itching, supplementing QI and nourishing YIN, promoting the circulation of QI to relieve pain are ministerial drug, Radix Glycyrrhizae is adjuvant, the mutual compatibility of full side, clearing away heat-damp and promoting diuresis, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, treatment gynecology colpitis successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Herba Veronicastri Sibirici 20g, Folium Aeschynomenes indicae 25g, Fructus Querci Liaotungensis 28g, Cortex Bretschneiderae Sinensis 26g, Semen Persicae 15g, Cortex Phellodendri 25g, Rhizoma Osmundae 28g, Radix Sophorae Flavescentis 15g, Folium Ilicis 15g, Radix Angelicae Sinensis 20g, Herba Patriniae 25g, Herba Paederiae 20g, Folium Ginkgo 25g, Folium Mori 20g, Fructus Evodiae 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Herba Veronicastri Sibirici 20g, Folium Aeschynomenes indicae 25g, Fructus Querci Liaotungensis 28g, Cortex Bretschneiderae Sinensis 26g, Semen Persicae 15g, Cortex Phellodendri 25g, Rhizoma Osmundae 28g, Radix Sophorae Flavescentis 15g, Folium Ilicis 15g, Radix Angelicae Sinensis 20g, Herba Patriniae 25g, Herba Paederiae 20g, Folium Ginkgo 25g, Folium Mori 20g, Fructus Evodiae 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Herba Veronicastri Sibirici 20g, Folium Aeschynomenes indicae 25g, Fructus Querci Liaotungensis 28g, Cortex Bretschneiderae Sinensis 26g, Semen Persicae 15g, Cortex Phellodendri 25g, Rhizoma Osmundae 28g, Radix Sophorae Flavescentis 15g, Folium Ilicis 15g, Radix Angelicae Sinensis 20g, Herba Patriniae 25g, Herba Paederiae 20g, Folium Ginkgo 25g, Folium Mori 20g, Fructus Evodiae 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, pharmaceutical preparation treatment vaginitis of the present invention clinical research
4.1 general data: this pharmaceutical preparation is applied to clinical observation case 60 example, 24 ~ 45 years old age.The shortest person of the course of disease 3 months, most elder reaches 3 years.
4.2 diagnostic criterias: (1) vaginal secretions milk sample homogenizing, frowziness.(2) vagina PH value >4.5.(3) amine test is positive.(4) the clues cell positive (>20%).In above-mentioned 4,3 positives get final product clinical diagnosis, and wherein the 4th article is diagnosis goldstandard.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule five days is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: recovery from illness: transference cure, vaginal secretions inspection is normal.Effective: vaginal secretions inspection is normal and its symptom does not disappear, or symptom alleviates and vaginal secretions inspection exception.Invalid: symptom and vaginal secretions inspection are with before treatment.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 30 | 12 | 14 | 4 | 86.7 |
| Blank group | 30 | 1 | 4 | 25 | 16.7 |
Visible, the medicine that the present invention obtains can safe and effective treatment vaginitis, and has no side effect.
Claims (4)
1. one kind is used for the treatment of the pharmaceutical preparation of gynecology colpitis, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Herba Veronicastri Sibirici 20 parts, Folium Aeschynomenes indicae 25 parts, Fructus Querci Liaotungensis 28 parts, Cortex Bretschneiderae Sinensis 26 parts, 15 parts, Semen Persicae, Cortex Phellodendri 25 parts, Rhizoma Osmundae 28 parts, Radix Sophorae Flavescentis 15 parts, Folium Ilicis 15 parts, Radix Angelicae Sinensis 20 parts, Herba Patriniae 25 parts, Herba Paederiae 20 parts, Folium Ginkgo 25 parts, 20 parts, Folium Mori, Fructus Evodiae 15 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the pharmaceutical preparation of gynecology colpitis as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the pharmaceutical preparation of gynecology colpitis as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of pharmaceutical preparation in treatment gynecology colpitis medicine of gynecology colpitis according to claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510799699.7A CN105267400A (en) | 2015-11-19 | 2015-11-19 | Medicine preparation for treating gynecological vaginitis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510799699.7A CN105267400A (en) | 2015-11-19 | 2015-11-19 | Medicine preparation for treating gynecological vaginitis |
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| CN105267400A true CN105267400A (en) | 2016-01-27 |
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| CN201510799699.7A Pending CN105267400A (en) | 2015-11-19 | 2015-11-19 | Medicine preparation for treating gynecological vaginitis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982360A (en) * | 2017-12-06 | 2018-05-04 | 苏州兰灵医药科技有限公司 | A kind of gelling agent and its application method for being used to treat vaginitis |
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2015
- 2015-11-19 CN CN201510799699.7A patent/CN105267400A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982360A (en) * | 2017-12-06 | 2018-05-04 | 苏州兰灵医药科技有限公司 | A kind of gelling agent and its application method for being used to treat vaginitis |
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Application publication date: 20160127 |