CN105055894A - Pharmaceutical preparation for treating lumbar muscle strain - Google Patents
Pharmaceutical preparation for treating lumbar muscle strain Download PDFInfo
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- CN105055894A CN105055894A CN201510601490.5A CN201510601490A CN105055894A CN 105055894 A CN105055894 A CN 105055894A CN 201510601490 A CN201510601490 A CN 201510601490A CN 105055894 A CN105055894 A CN 105055894A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations and particularly provides a pharmaceutical preparation for treating lumbar muscle strain prepared from the following raw materials: 25 parts of falsenettleleaf pepper stems, 20 parts of twoleaf beadruby herbs, 18 parts of twoanther mosla herbs, 18 parts of Chinese pholidota herbs, 25 parts of cynanchum paniculatum, 15 parts of salvia miltiorrhiza, 20 parts of radix achyranthis bidentatae, 20 parts of cynomorium songaricum, 25 parts of radix clematidis, 25 parts of fructus viticis, 20 parts of olibanum, 15 parts of astragalus, 18 parts of semen cuscutae, 15 parts of eucommia ulmoides, 20 parts of safflowers, 15 parts of radix saposhnikoviae and 5 parts of liquorice. The pharmaceutical preparation can be used for treating lumbar muscle strain.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of lumbar muscle strain and its preparation method and application.
Background technology
Lumbar muscle strain refers to the chronic injury of the soft tissues such as waist muscle, fascia and ligament, is modal disease in lumbago and skelalgia, also known as functional lumbago, chronic lower waist strain etc.Primary disease is apt to occur in adult, and its clinical symptoms is waist or waist and sacrum pain, and recurrent exerbation pain can climate change or tired degree and change, time heavy time light, touchingly not heal.The pathogenic factor of lumbar muscle strain can be summarized as three: 1, long-term work posture is bad, as bent over to lift weight or habitual poor posture pickaback with side, make psoas muscle be in drawing-off state for a long time, cause cumulative bad strain degeneration, soft tissue fatigue then produces aching pain in waist and back.2, the congenital or acquired deformity of lumbar vertebra, or Treating Lower Limb Discrepancy, or after waist wound, long-term bed, low back muscle length is tired.3, lumbar soft tissue acute injury malpractice, or repeatedly make tissue do not repaired, producing fibrosis or cicatrization, is also the reason of lumbago.At present, the method for the treatment of lumbar muscle strain is a lot, and as physical therapy, take anti-inflammation analgesic or operative treatment, though there is certain curative effect, effect is all undesirable.For this reason, be bursting to and develop the needs that more medicines for the treatment of lumbar muscle strain safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of lumbar muscle strain disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of lumbar muscle strain, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: blue 25 parts of Spica piperis betlis, Herba Maianthemi Bifolii 20 parts, Heraba Moslae Diantherae 18 parts, Pseudobulbus Pholidotae Chinensis 18 parts, Radix Cynanchi Paniculati 25 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Achyranthis Bidentatae 20 parts, Herba Cynomorii 20 parts, Radix Clematidis 25 parts, Fructus Viticis 25 parts, Olibanum 20 parts, the Radix Astragali 15 parts, Semen Cuscutae 18 parts, the Cortex Eucommiae 15 parts, 20 parts, Flos Carthami, Radix Saposhnikoviae 15 parts, 5 parts, Radix Glycyrrhizae.
The described pharmaceutical preparation being used for the treatment of lumbar muscle strain, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of lumbar muscle strain, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of pharmaceutical preparation in preparation treatment lumbar muscle strain medicine being used for the treatment of lumbar muscle strain.
Spica piperis betlis is blue, and Piperaceae Piper plant folium urticae Fructus Piperis, is used as medicine with Herb.The whole year can adopt, and section is dried.Regulating QI to relieve pain.For flu, stomachache, dysmenorrhea, traumatic injury, rheumatic ostalgia.
Herba Maianthemi Bifolii is the herb of liliaceous plant Herba Maianthemi Bifolii, and Classification system is Maianthemumbifolium (L.) Fr.Schmidt, the present invention with all herbal medicine,
Heraba Moslae Diantherae is the herb of labiate flower thinning Ji thuja.Dispel the wind pleasant, warming middle-JIAO to relieve pain.Cure the wound summer-heat abdominal distention, and eruptive disease is had a pain; Hemorrhoid complicated by anal fistula hematochezia.
Pseudobulbus Pholidotae Chinensis is herb or the pseudobulb of monocotyledon medicine the orchid family peach family plant seed Pseudobulbus Pholidotae Chinensis.Nourishing the lung to arrest cough, silt releasing and analgesia.For pulmonary tuberculosis cough, cough with asthma QI rising in reverse order person.For the traumatic injury person of swelling and ache.The present invention is with all herbal medicine.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science thinks that waist is house of kidney, owing to straining in kidney, or body is empty usually, and kidney qi is weak, and the vital essence of kidney can not be supplemented nutrition muscles and bones meridians, therefore affected part mostly is the smooth or congestion of QI and blood is stranded in meridians, and the not flourish muscle of blood, muscle arteries and veins does not relax, and causes waist spasm pain.Spica piperis betlis orchid of the present invention, Herba Maianthemi Bifolii, Heraba Moslae Diantherae, Pseudobulbus Pholidotae Chinensis, Radix Cynanchi Paniculati, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Herba Cynomorii heat-clearing and toxic substances removing, soothing the channels and quicking the network vessels, blood circulation promoting and blood stasis dispelling are monarch drug, Radix Clematidis, Fructus Viticis, Olibanum, the Radix Astragali, Semen Cuscutae, the Cortex Eucommiae, Flos Carthami, Radix Saposhnikoviae reinforcing spleen and kidney, blood circulation promoting and blood stasis dispelling are ministerial drug, Radix Glycyrrhizae is adjuvant, the mutual compatibility of full side, blood circulation promoting and blood stasis dispelling, soothing the channels and quicking the network vessels, reinforcing spleen and kidney, treatment lumbar muscle strain successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get the blue 25g of mao Spica piperis betlis, Herba Maianthemi Bifolii 20g, Heraba Moslae Diantherae 18g, Pseudobulbus Pholidotae Chinensis 18g, Radix Cynanchi Paniculati 25g, Radix Salviae Miltiorrhizae 15g, Radix Achyranthis Bidentatae 20g, Herba Cynomorii 20g, Radix Clematidis 25g, Fructus Viticis 25g, Olibanum 20g, Radix Astragali 15g, Semen Cuscutae 18g, Cortex Eucommiae 15g, Flos Carthami 20g, Radix Saposhnikoviae 15g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, and atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get the blue 25g of mao Spica piperis betlis, Herba Maianthemi Bifolii 20g, Heraba Moslae Diantherae 18g, Pseudobulbus Pholidotae Chinensis 18g, Radix Cynanchi Paniculati 25g, Radix Salviae Miltiorrhizae 15g, Radix Achyranthis Bidentatae 20g, Herba Cynomorii 20g, Radix Clematidis 25g, Fructus Viticis 25g, Olibanum 20g, Radix Astragali 15g, Semen Cuscutae 18g, Cortex Eucommiae 15g, Flos Carthami 20g, Radix Saposhnikoviae 15g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, adds dextrin 50g, granulates, tabletting, makes tablet.
3, the preparation of capsule embodiment: get the blue 25g of mao Spica piperis betlis, Herba Maianthemi Bifolii 20g, Heraba Moslae Diantherae 18g, Pseudobulbus Pholidotae Chinensis 18g, Radix Cynanchi Paniculati 25g, Radix Salviae Miltiorrhizae 15g, Radix Achyranthis Bidentatae 20g, Herba Cynomorii 20g, Radix Clematidis 25g, Fructus Viticis 25g, Olibanum 20g, Radix Astragali 15g, Semen Cuscutae 18g, Cortex Eucommiae 15g, Flos Carthami 20g, Radix Saposhnikoviae 15g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, and leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, adds starch 50g, granulates, fill, makes capsule.
4, pharmaceutical preparation treatment lumbar muscle strain of the present invention clinical research
4.1 general data: this pharmaceutical preparation is applied to clinical observation lumbar muscle strain case 70 example, 48 ~ 65 years old age.The shortest person of the course of disease 6 months, most elder reaches 2 years.
4.2 diagnostic criterias: the diagnostic criteria with reference to lumbar muscle strain in People's Republic of China's traditional Chinese medicine industry standard " Chinese medical disease Standardization of diagnosis and curative effect ": 1, waist is ached or distending pain, part twinge or causalgia; 2, increase the weight of during fatigue, alleviate during rest; Alleviate when suitable activity and often change position, hyperkinesia increases the weight of again; 3, can not the work of bending over be adhered to, often be forced to straighten one's back or hit waist with alleviating pain with fist; 4, waist has pressure pain point, how at musculus sacrospinalis place, and musculus sacrospinalis stop place or transverse process of lumbar vertebra place behind ilium ridge rear portion, rumpbone; 5, waist profile and activity how without exception, also without obvious psoas muscle spasm, the activity of small number of patients waist is slightly limited.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule five days is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: recovery from illness: lumbago transference cure, psoas muscle tension force is normal, can normally work; Effective: lumbago symptom obviously alleviates, psoas muscle is slightly nervous, and waist activity still has limited; Effective: lumbago symptom alleviates, psoas muscle anxiety is comparatively front to be alleviated, and waist activity is still limited; Invalid: lumbago is without improvement, and waist is movable without recovering.。
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 35 | 12 | 10 | 8 | 3 | 91.4 |
| Blank group | 35 | 2 | 1 | 1 | 31 | 11.4 |
Visible, the medicine that the present invention obtains can safe and effective treatment lumbar muscle strain, and has no side effect.
Claims (4)
1. one kind is used for the treatment of the pharmaceutical preparation of lumbar muscle strain, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: blue 25 parts of Spica piperis betlis, Herba Maianthemi Bifolii 20 parts, Heraba Moslae Diantherae 18 parts, Pseudobulbus Pholidotae Chinensis 18 parts, Radix Cynanchi Paniculati 25 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Achyranthis Bidentatae 20 parts, Herba Cynomorii 20 parts, Radix Clematidis 25 parts, Fructus Viticis 25 parts, Olibanum 20 parts, the Radix Astragali 15 parts, Semen Cuscutae 18 parts, the Cortex Eucommiae 15 parts, 20 parts, Flos Carthami, Radix Saposhnikoviae 15 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the pharmaceutical preparation of lumbar muscle strain as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the pharmaceutical preparation of lumbar muscle strain as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of pharmaceutical preparation in treatment lumbar muscle strain medicine of lumbar muscle strain according to claim 1.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510601490.5A CN105055894A (en) | 2015-09-19 | 2015-09-19 | Pharmaceutical preparation for treating lumbar muscle strain |
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| CN201510601490.5A CN105055894A (en) | 2015-09-19 | 2015-09-19 | Pharmaceutical preparation for treating lumbar muscle strain |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267710A (en) * | 2015-11-25 | 2016-01-27 | 苏州枫灵医药科技有限公司 | Pharmaceutical preparation used for treating lumbar muscle strain |
| CN112274551A (en) * | 2020-10-23 | 2021-01-29 | 江西普正制药股份有限公司 | Eucommia ulmoides extract and application thereof in treating lumbar disc degeneration diseases |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103356953A (en) * | 2013-06-24 | 2013-10-23 | 柳晖 | Chinese medicine composition for treating lumbar muscle degeneration |
| CN104784618A (en) * | 2015-04-23 | 2015-07-22 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine composition for treating headache |
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2015
- 2015-09-19 CN CN201510601490.5A patent/CN105055894A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103356953A (en) * | 2013-06-24 | 2013-10-23 | 柳晖 | Chinese medicine composition for treating lumbar muscle degeneration |
| CN104784618A (en) * | 2015-04-23 | 2015-07-22 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine composition for treating headache |
Non-Patent Citations (1)
| Title |
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| 胡加富 等: "白芍木瓜汤并针刺治疗腰肌劳损", 《中国临床康复》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267710A (en) * | 2015-11-25 | 2016-01-27 | 苏州枫灵医药科技有限公司 | Pharmaceutical preparation used for treating lumbar muscle strain |
| CN112274551A (en) * | 2020-10-23 | 2021-01-29 | 江西普正制药股份有限公司 | Eucommia ulmoides extract and application thereof in treating lumbar disc degeneration diseases |
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