CN105079674A - Medicinal preparation for treating chest stuffiness and pains - Google Patents
Medicinal preparation for treating chest stuffiness and pains Download PDFInfo
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- CN105079674A CN105079674A CN201510575523.3A CN201510575523A CN105079674A CN 105079674 A CN105079674 A CN 105079674A CN 201510575523 A CN201510575523 A CN 201510575523A CN 105079674 A CN105079674 A CN 105079674A
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Abstract
The invention belongs to the field of traditional Chinese medicine preparations, and particularly provides a medicinal preparation for treating chest stuffiness and pains. The medicinal preparation is prepared from the following raw materials in parts by weight: 28 parts of herba monochoria korsakowii, 20 parts of Nothopanax delavayi (Franch.) Harms ex Diels, 25 parts of rhizome Rodgersia pinnata Franch, 18 parts of rhizoma panacis majoris, 25 parts of herba rhodiolae, 15 parts of radix salviae miltiorrhizae, 20 parts of radices paeoniae alba, 20 parts of trichosanthes kirilowii maxim, 25 parts of peach kernels, 25 parts of fructus amomi, 20 parts of coptis chinensis, 15 parts of astragalus membranaceus, 18 parts of ligusticum wallichii, 15 parts of radix paeoniae rubra, 20 parts of safflower carthamus, 15 parts of schisandra chinensis and 5 parts of licorice root. The medicinal preparation can treat chest stuffiness and pains.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of pharmaceutical preparation being used for the treatment of obstruction of qi in the chest and cardialgia and its preparation method and application.
Background technology
Obstruction of qi in the chest and cardialgia refer to feel oppressed with chest pain, one that shortness of breath and palpitation is primary symptom feels concerned about disease.Uncomfortable in chest or the chest dull pain of the lighter, shows effect of short duration; Severe one chest pain radiating to the back, backache radiating to the heart, failing to sleep due to dyspnea, pain is drawn inside left shoulder or left arm.Normal with shortness of breath and palpitation, hypopnea, very then dyspnea with rapid and short breath, pale complexion, dripping cold sweat etc.How by tired heavy meal, cold or excited and bring out.For this reason, be bursting to and develop the needs that more medicines for the treatment of obstruction of qi in the chest and cardialgia safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of obstruction of qi in the chest and cardialgia disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of pharmaceutical preparation being used for the treatment of obstruction of qi in the chest and cardialgia, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Monochoria korsakowii 28 parts, Herba seu Radix Nothopanacis delavayi 20 parts, Serpentis pimple 25 parts, Rhizoma Panacis Majoris 18 parts, Radix Rhodiolae 25 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Paeoniae Alba 20 parts, Fructus Trichosanthis 20 parts, 25 parts, Semen Persicae, Fructus Amomi 25 parts, Rhizoma Coptidis 20 parts, the Radix Astragali 15 parts, Rhizoma Chuanxiong 18 parts, Radix Paeoniae Rubra 15 parts, 20 parts, Flos Carthami, Fructus Schisandrae Chinensis 15 parts, 5 parts, Radix Glycyrrhizae.
The described pharmaceutical preparation being used for the treatment of obstruction of qi in the chest and cardialgia, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described pharmaceutical preparation being used for the treatment of obstruction of qi in the chest and cardialgia, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
The described application of pharmaceutical preparation in preparation treatment obstruction of qi in the chest and cardialgia medicine being used for the treatment of obstruction of qi in the chest and cardialgia.
Monochoria korsakowii, formal name used at school is Monochoriakorsakowii, is a kind of Pontederiaceae plant.Primary growth is in on-swimmer's pool, pool, limes marginis or marshland.This plant distributions is in provinces and regions such as China Dark Longjiang, Jilin, Liaoning, the Inner Mongol, Hebei, Henan, Shandong, Shanxi, Shaanxi, Jiangsu, Anhui, Zhejiang, Jiangxi, Hubei, Hunan.In addition, Korea, Russia, Japan also have.Heat-clearing and toxic substances removing.Breathe heavily for high heat syndrome cough, infantile erysipelas.The present invention is with all herbal medicine.
Herba seu Radix Nothopanacis delavayi is Herb or the root of Araliaceae Nothopanax, and spring, summer gather, and cleans using fresh herb or dries use.Heat-clearing and toxic substances removing, relaxing muscles and tendons to promote blood circulation.For acute pharyngitis, acute conjunctivitis, dyspepsia, lumbago, skelalgia of rheumatism; Fracture is controlled in external, traumatic injury.The present invention is used as medicine with Herb.
Serpentis pimple is Saxifragaceae Rodgersia podophylla A. Gray platymiscium Rodgersia pinnata RodgersiapinnataFranch., is used as medicine with root stock.Xia Qiu gathers, and dries.Anti-inflammtory anti-dysentery, menstruction regulating and pain relieving, hemostasis.For enteritis, bacillary dysentery, menoxenia, dysmenorrhea, rheumatalgia, fracture, traumatic injury swelling and pain due to blood stasis.
Rhizoma Panacis Majoris derives from Araliaceae, Panax, the dry root stock of Panax pseudoginseng Wall. Subgenus Rhizoma Panacis Majoris PanaxpseudoginsengWall.var.major (Burkill) H.L.Li, tonifying the lung, and yin nourishing is active, hemostasis.For deficiency of both QI and YIN, dysphoria with smothery sensation is thirsty, cough due to consumptive disease, injury from falling down, arthralgia, hemoptysis, spits blood, traumatic hemorrhage.All the other Chinese medicines are pharmacopeia kind.
Beneficial effect: the traditional Chinese medical science thinks that obstruction of qi in the chest and cardialgia refers to that hypofunction of YANG QI in chest, QI and blood numbness hinder, card is shown in sensation of oppression over the chest with shortness of breath very then ambition pain; Pained then because of the heart yang blood and qi deficiency, caused by qi and cold stagnation, stagnation of phlegm blood vessels etc. caused by, demonstrate,prove based on ambition pain.The depletion fire syndrome going up that the blockage of the cardiac vessels cause of disease causes based on YIN-deficiency of the lung and kidney, throat lose and support.Monochoria korsakowii of the present invention, Herba seu Radix Nothopanacis delavayi, Serpentis pimple, Rhizoma Panacis Majoris, Radix Rhodiolae, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Trichosanthis, Semen Persicae, Fructus Amomi, Rhizoma Coptidis, the Radix Astragali activate yang let out turbid, eliminating phlegm relieving accumulation of pathogens is monarch drug, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Flos Carthami, Fructus Schisandrae Chinensis blood circulation promoting and blood stasis dispelling are ministerial drug, Radix Glycyrrhizae is adjuvant, the mutual compatibility of full side, treatment obstruction of qi in the chest and cardialgia successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Monochoria korsakowii 28g, Herba seu Radix Nothopanacis delavayi 20g, Serpentis pimple 25g, Rhizoma Panacis Majoris 18g, Radix Rhodiolae 25g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Alba 20g, Fructus Trichosanthis 20g, Semen Persicae 25g, Fructus Amomi 25g, Rhizoma Coptidis 20g, Radix Astragali 15g, Rhizoma Chuanxiong 18g, Radix Paeoniae Rubra 15g, Flos Carthami 20g, Fructus Schisandrae Chinensis 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Monochoria korsakowii 28g, Herba seu Radix Nothopanacis delavayi 20g, Serpentis pimple 25g, Rhizoma Panacis Majoris 18g, Radix Rhodiolae 25g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Alba 20g, Fructus Trichosanthis 20g, Semen Persicae 25g, Fructus Amomi 25g, Rhizoma Coptidis 20g, Radix Astragali 15g, Rhizoma Chuanxiong 18g, Radix Paeoniae Rubra 15g, Flos Carthami 20g, Fructus Schisandrae Chinensis 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Monochoria korsakowii 28g, Herba seu Radix Nothopanacis delavayi 20g, Serpentis pimple 25g, Rhizoma Panacis Majoris 18g, Radix Rhodiolae 25g, Radix Salviae Miltiorrhizae 15g, Radix Paeoniae Alba 20g, Fructus Trichosanthis 20g, Semen Persicae 25g, Fructus Amomi 25g, Rhizoma Coptidis 20g, Radix Astragali 15g, Rhizoma Chuanxiong 18g, Radix Paeoniae Rubra 15g, Flos Carthami 20g, Fructus Schisandrae Chinensis 15g, Radix Glycyrrhizae 5g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, pharmaceutical preparation treatment obstruction of qi in the chest and cardialgia of the present invention clinical research
4.1 general data: this pharmaceutical preparation is applied to clinical observation obstruction of qi in the chest and cardialgia case 50 example, 49 ~ 68 years old age.The shortest person of the course of disease 4 months, most elder reaches 1 year.
4.2 diagnostic criterias: one, with precordialgia, feel oppressed, lose heart for primary symptom.The ictal pain in after showing as breastbone or breast breast portion is often angor, twinge or dull pain; The positions such as pain can be radiated inside the left shoulder back of the body, left arm, neck, throat, time when doing only, recurrent exerbation; Pain generally to continue more than tens of second to ten minute, is generally no more than 30 minutes. can alleviate after having a rest or taking medicine.Many with severe palpitation, weak, hypopnea of losing heart, very then dyspnea with rapid and short breath, complexion are grey from, spontaneous perspiration etc.Clinical is many with the deficiency of vital energy, yang deficiency, the deficiency of YIN, blood stasis, the stagnation of QI, pathogenesis that expectorant is turbid.Visible corresponding picture of the tongue, pulse condition.Two, crowd above middle age is common, the factor such as Chang Yin overworks, seven emotions are too drastic, climate change, carousing are satiated with food and bringing out.Part is without morbidity when obvious inducement or peace and quiet.
4.3 test methods: prepare clinical sample by above-mentioned process for producing granula, specification is 10 grams every bag, within five days, is a course for the treatment of, one day three bags, take point early, middle and late three half an hour ante cibum.Period in a medicine is avoided eating anything raw or cold, pungent, stimulate and rotten thing.Blank group oral placebo granule five days is a course for the treatment of, one day three bags, point early, middle and late three half an hour ante cibum take.
4.4 criterions of therapeutical effect: recovery from illness: symptom all disappears; Effective: symptom obviously alleviates; Invalid: without significant change or deterioration before and after treatment.
4.5 therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 25 | 12 | 9 | 4 | 96 |
| Blank group | 25 | 1 | 1 | 23 | 8 |
Visible, the medicine that the present invention obtains can safe and effective treatment obstruction of qi in the chest and cardialgia, and has no side effect.
Claims (4)
1. one kind is used for the treatment of the pharmaceutical preparation of obstruction of qi in the chest and cardialgia, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Monochoria korsakowii 28 parts, Herba seu Radix Nothopanacis delavayi 20 parts, Serpentis pimple 25 parts, Rhizoma Panacis Majoris 18 parts, Radix Rhodiolae 25 parts, Radix Salviae Miltiorrhizae 15 parts, the Radix Paeoniae Alba 20 parts, Fructus Trichosanthis 20 parts, 25 parts, Semen Persicae, Fructus Amomi 25 parts, Rhizoma Coptidis 20 parts, the Radix Astragali 15 parts, Rhizoma Chuanxiong 18 parts, Radix Paeoniae Rubra 15 parts, 20 parts, Flos Carthami, Fructus Schisandrae Chinensis 15 parts, 5 parts, Radix Glycyrrhizae.
2. be used for the treatment of the pharmaceutical preparation of obstruction of qi in the chest and cardialgia as claimed in claim 1, it is characterized in that, dosage form is pharmaceutically acceptable granule, tablet, capsule.
3. be used for the treatment of the pharmaceutical preparation of obstruction of qi in the chest and cardialgia as claimed in claim 1, it is characterized in that, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make capsule, tablet, granule.
4. be used for the treatment of the application of pharmaceutical preparation in treatment obstruction of qi in the chest and cardialgia medicine of obstruction of qi in the chest and cardialgia according to claim 1.
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| CN201510575523.3A CN105079674A (en) | 2015-09-10 | 2015-09-10 | Medicinal preparation for treating chest stuffiness and pains |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816830A (en) * | 2016-03-24 | 2016-08-03 | 杨万勇 | Traditional Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816830A (en) * | 2016-03-24 | 2016-08-03 | 杨万勇 | Traditional Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy and preparation method thereof |
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