CN105816830A - Traditional Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy and preparation method thereof Download PDF

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CN105816830A
CN105816830A CN201610170825.7A CN201610170825A CN105816830A CN 105816830 A CN105816830 A CN 105816830A CN 201610170825 A CN201610170825 A CN 201610170825A CN 105816830 A CN105816830 A CN 105816830A
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rhizoma
chinese medicine
radix
medicine preparation
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杨万勇
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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Abstract

The invention belongs to the field of traditional Chinese medicine inventions, and discloses a traditional Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy. The traditional Chinese medicine is prepared from fried peach kernels, red flowers, ligusticum wallichii, the roots of red-rooted salvia, spina gleditsiae, rhizoma sparganii, curcuma zedoary, fructus amomi, rhizome zingiberis, black prepared lateral root of aconite, cinnamon, rhizome galangae, pericarpium citri reticulatae viride, dried tangerine or orange peel, radix aucklandiae, agilawood, the roots of three-nerved spicebush, toosendan fruits, rhizoma corydalis, trogopterus dung, eupolyphoge sinensis, artemisia anomala, raw hawthorn and roses. According to different characters of the traditional Chinese medicines, the medicines are cleaned, sliced, preprocessed, matched proportionally, and manufactured through a special method, the traditional Chinese medicine preparation has the effects of warming the middle warmer, supporting Yang, restoring Yang, absorbing qi, activating blood, dissipating blood stasis, and inducing menstruation to relieve menalgia, the product composition and manufacturing method are unique, and according to clinical verifications, the traditional Chinese medicine preparation is remarkable in treatment effect, short in treatment period, low in cost and free of adverse reaction or toxic or side effect, and has the wide market application prospect.

Description

A kind of Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy and preparation method
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy, the invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Hypertrophic obstructive cardiomyopathy was once referred to as flesh under aortic valve and blocked.Ventricular septum height is plump, and its thickness is considerably beyond left ventricular free wall.And myocardial cell is thick and short, arrangement is mixed and disorderly, the laterally attached abundant referred to as asymmetric septal hypertrophy of iuntercellular.
Chinese medicine is thought, primary disease is due to healthy energy virtual loss, blood stasis, the stagnation of QI, the cold coagulation numbness resistance heart arteries and veins turbid with expectorant that diet, feelings will, cold-evil etc. are caused, ictal feels oppressed with Danzhong or left chest, the pain a kind of disease as main clinical manifestation.
At present, hypertrophic obstructive cardiomyopathy there is no specific short.Verapamil, diltiazem etc. have certain curative effect to primary disease treatment.But the long-term or short time uses these medicines to treat, the rising of obesity, hirsutism, acne, blood glucose, hypertension, edema, Nausea and vomiting, dizziness can be caused, constipation etc. series of side effects symptom, and the dependency that medicine created, after drug withdrawal, primary affection knock-on increases the weight of the side effect with secondary, and patient can be made to produce the biggest misery, therapeutic process is again and again, DeGrain, expense is high, causes bigger pressure at heart and ailing pressure to patient.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy, it is notable that this Chinese medicine preparation has therapeutic effect for treatment hypertrophic obstructive cardiomyopathy, healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
Inventor is in clinical treatment for many years is put into practice, according to the law of development of this disease, and the combination principle of Chinese medicine, and by substantial amounts of clinical verification, Exploration and conclusion goes out the new formula of the Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy repeatedly.It is notable that the present invention has therapeutic effect, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
The effect of Chinese medicine of the present invention:
Wherein:
Semen Persicae (parched): be the parched medicinal material of Semen Persicae.Semen Persicae: for rosaceous plant Fructus Persicae Prunus Persica (L.) Batsch or the dry mature seed of Prunus davidiana Prunus davidiana (Carr.) Franch..Nature and flavor: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Effect: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea, abdominal mass mass in the abdomen, injury from falling down, dryness of the intestine constipation.Described in " herbal classic ": main blood stasis, blood closes lump in the abdomen, pathogen, kills small worm." not Lu ": only cough with dyspnea, disappear hardness in the epigastrium, except soldier hits blood cruelly, broken lump in the abdomen, promote blood circulation, pain relieving.
Flos Carthami: for the dry flower of feverfew Flos Carthami Carthamus tinctorius L..Nature and flavor: pungent, temperature.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache." detailed outline ": invigorate blood circulation, moisturizes, pain relieving, dissipates swollen, stimulates the menstrual flow.
Rhizoma Chuanxiong: for samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort.(or Ligusticum wallichii Franch.) dry rhizome.Nature and flavor: pungent, temperature.Return liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen stomachache, breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia.Described in " Japan hanako materia medica ": control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, strengthening bone and muscle, adjust crowd's arteries and veins, broken knot stagnated blood, support fresh blood, put on flesh, serious epistaxis, to spit blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, scrofula wart is superfluous, skin ulcer scabies, and evacuation of pus repercussive blood.
Radix Salviae Miltiorrhizae: for the dry root and rhizome of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bunge..Nature and flavor: bitter, are slightly cold.GUIXIN, Liver Channel.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, chest and abdomen twinge, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia；Hepatosplenomegaly, angina pectoris.Described in " the southern regions of the Yunnan Province book on Chinese herbal medicine ": reinforcing the heart sedate, calming heart and tranquilizing mind.Controlling forgetful punching seized with terror, palpitation with fear is insomnia.
Spina Gleditsiae: for the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..Nature and flavor: pungent, temperature.Return liver, stomach warp.Effect: detumescence poison holding, evacuation of pus, parasite killing.For carbuncle from the beginning of or difficulty in discharging of pus；External treatment scabies leprosy.Described in " detailed outline ": control carbuncle, acute mastitis, scrofula caused by pathogenic wind malignant boil, retention of placenta, parasite killing.
Rhizoma Sparganii: for the dry tuber of Sparganiaceae plant rhizoma scirpi Sparganium stoloniferum Buch.-Ham..Nature and flavor: pungent, bitter are flat.Return liver, spleen channel.Effect: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.Described in " Japan hanako materia medica ": control married woman's blood vessels uncomfortable, cardiac and abdominal pain, fall tire, and disappear stagnant blood, mends labor, logical menstruation, controls flatulence, disappear and flutter damage blood stasis, puerperal abdonimal pain, blood fortune stagnated blood not under.
Rhizoma Curcumae: for zingiberaceous plant Rhizoma Curcumae Curcuma phaeocaulis Val., Guangxi zedoary Curcuma Kwangsiensis S. G.Lee et C. F. Liang or the dry rhizome of RADIX CURCUMAE Curcuma wenyujin Y.H. Chen et C. Ling.Nature and flavor: pungent, bitter, temperature.Return liver, spleen channel.Effect: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain；Early cervical carcinoma.
Fructus Amomi: for zingiberaceous plant Fructus Amomi Amomum villosum Lour., green shell sand Amomum villosum Lour. var. Xanthioides T. L. Wu et Senjen or SEMEN AMOMI LONGILIGULA Amomum The dry mature fruit of longiligulare T. L. Wu.Nature and flavor: pungent, temperature.Return spleen, stomach, kidney channel.Effect: removing dampness is whetted the appetite, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is the most hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.Described in " Japan hanako materia medica ": control all gas, cramp caused by acute vomiting and diarrhea, cardiac and abdominal pain.
Rhizoma Zingiberis: for the dry rhizome of zingiber Zingiber officinale Rosc..Nature and flavor: pungent, hot.Return spleen, stomach, kidney, the heart, lung meridian.Effect: warming spleen and stomach for dispelling cold, recuperating depleted YANG promotes blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, cold extremities faint pulse, and phlegm retention is breathed with cough.Described in " detailed outline ": Rhizoma Zingiberis, can draw that blood medicine enters blood system, gas medicine enters edema caused by disorder of QI.Can go again to dislike to support newly, have the meaning of Yin grows while yang is generating.
Cortex Cinnamomi: for canella Cortex Cinnamomi Cinnamomum The dry bark of cassia Presl.Nature and flavor: pungent, sweet are the warmmest.Return kidney, spleen, the heart, Liver Channel.Effect: mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffer from a deficiency of the kidney and breathe heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea." not Lu ": main pained, coerces wind, hypochondriac pain, temperature muscle, promotes blood circulation, the most tired, perspire.
Radix Aconiti Lateralis Preparata: for the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx. Aconitum carmichaeli Debx..Nature and flavor: pungent, sweet are the warmmest；Poisonous.GUIXIN, kidney, spleen channel.Effect: recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.Collapse for YANG-depletion, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.Described in " not Lu ": foot pain is cold weak, spinal column wind and cold, trusted subordinate's cold type of pain, cramp caused by acute vomiting and diarrhea, and dysentery is red in vain, hard flesh bone, reinforcing YIN-essence, a word used in place name of falling again, be that hundred medicines are long.
Rhizoma Alpiniae Officinarum: for the dry rhizome of zingiberaceous plant Rhizoma Alpiniae Officinarum Alpinia officinarum Hance.Nature and flavor: pungent, heat.Return spleen, stomach warp.Effect: warming stomach for dispelling cold, help digestion pain relieving.For coldness and pain in the epigastrium, gastrofrigid vomiting, belch acid regurgitation.Described in supplement to the Herbal: the therapeutic method to keep the adverse QI flowing downwards, benefit sound.Boil make drink-service it, dysentery relieving and cholera.
Pericarpium Citri Reticulatae: for rutaceae orange Citrus Reticulata Blanco and the dry mature skin of variety thereof.Nature and flavor: bitter, pungent, temperature.Return lung, spleen channel.Effect: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Pericarpium Citri Reticulatae Viride: for rutaceae orange Citrus Reticulata Blanco and the dry young fruit of variety thereof or the peel of immature fruit.Nature and flavor: bitter, pungent, temperature.Return liver, gallbladder, stomach warp.Effect: soothing the liver dispelling the stagnated QI, removing food stagnancyization is stagnant.For distending pain in the chest and hypochondrium, hernia, nodule in the breast, acute mastitis, abdominal pain due to retention of food.Described in essentials of Matea Medica: expectorant disappears painful abdominal mass, controls depression of liver-QI, the many anger of hypochondriac pain, chronic malaria knot addiction, colic, swelling of the breast.
The Radix Aucklandiae: for the dry root of feverfew Radix Aucklandiae Aucklandia lappa Decne..Nature and flavor: pungent, bitter, temperature.Return spleen, stomach, large intestine, three burnt, gallbladder meridians.Effect: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For breast gastral cavity distending pain, weight after dysentery, food stagnation does not disappears, anorexia.Radix Aucklandiae (roasted) reality intestinal antidiarrheal.For stomachache of having loose bowels.Described in " not Lu ": treat that gas is bad, the coldest in flesh；Main QI-insufficiency, sterilization, (controlling) pyrexial malaria, the essence of row medicine.
Lignum Aquilariae Resinatum: contain the timber of resin for Isolated From Thymelaeaceae Species Lignum Aquilariae Resinatum Aquilaria sinensis (Lour.) Gilg.Nature and flavor: pungent, bitter, tepor.Return spleen, stomach, kidney channel.Effect: promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma.For chest and abdomen feeling of distension and oppression pain, gastrofrigid vomiting singultus, QI rising in reverse order of suffering from a deficiency of the kidney dyspnea with rapid respiration.Described in " medical center bun is wanted ": hard kidney, mending the gate of vitality, warming middle-JIAO, dry spleen are wet, removing pathogen in the heart, lowering the adverse flow of QI, and all uncomfortable gas all can adjust it.And control keep silent mouthful fulminant dysentery and evil cold wind arthralgia due to cold.
The Radix Linderae: for canella Radix Linderae Lindera Aggregata (Sims) Kosterm. Dried root.Nature and flavor: pungent, temperature.Return lung, spleen, kidney, bladder warp.Effect: pleasant pain relieving, warming kidney for dispelling cold.For chest and abdomen swelling and pain, QI rising in reverse order dyspnea with rapid respiration, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia, dysmenorrhea.Described in " explaining abstruseness of the canon of materia medica ": reason seven emotions pent-up, QI and blood is solidifying stops, and cholera is vomited and diarrhoea, and expectorant food is delaied.
Fructus Toosendan: for the dry mature fruit of Meliaceae plant Fructus Toosendan Melia toosendan Sieb. et Zucc..Nature and flavor: bitter, cold；Slightly poisonous.Return liver, small intestinal, bladder warp.Effect: soothing liver-QI circulation of qi promoting, pain relieving anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.Described in " medical center bun is wanted ": eliminating heart-fire, hard kidney water, lung heat clearing gold, clearing away liver-fire.Core: happy hernia, removes syndrome of aversion to cold lasting day and night with cold limbs.
Rhizoma Corydalis: for the dry tuber of papaveraceae plant corydalis Corydalis yanhusuo W. T. Wang.Nature and flavor: pungent, bitter, temperature.Return liver, spleen channel.Effect: invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Described in " Japan hanako materia medica ": except wind, control gas, warm waist knee joint, broken disease addiction, flutter damage blood stasis, fall tire, and sudden and violent lumbago.
Oletum Trogopterori: for flying squirrel section animal trogopterus xanthipes Trogopterus Xanthipes Milne-Edwards or fly murine little flying squirrel Pteromys volans L. dry feces.Nature and flavor: sweet, temperature.Effect: promoting blood circulation to remove blood stasis, parch to black stops blooding.Having a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, curing postpartum bleeding is suffered from abdominal pain；Parch to black controls metrostaxis；Traumatic injury, Serpentis, insect bite wound are controlled in external.Described in " Amplification on Materia Medica addendum ": can promoting the circulation of blood hemostasis.Controlling trusted subordinate's cold air, married woman is pained, pricking caused by the stagnation of QI and blood.
Worm: for Corydiidae insecticide eupolyphoge sinensis Eupolyphaga Sinensis Walker or Ji eupolyphoge sinensis Steleophaga Plancyi(Boleny) female worm dry body.Nature and flavor: salty, cold；Slightly poisonous.Return Liver Channel.Effect: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.
Herba Artemisiae Anomalae: for the herb of feverfew artemisia anomalas.Nature and flavor: bitter, temperature.GUIXIN, spleen channel.Effect: removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling.Control amenorrhea lump in the abdomen, chest and abdomen swelling and pain, puerperal blood stasis, traumatic injury, incised wound is hemorrhage, and carbuncle poison swells.Described in Tang Materia Medica: main removing blood stasis, under swollen.
Fructus Crataegi: for rosaceous plant Fructus Pyri Pashiae Crataegus pinnatifida Bge.var.major N.E.Br. or the dry mature fruit of Fructus Crataegi Crataegus pinnatifida Bge..Nature and flavor: sour, sweet, tepor.Return spleen, stomach, Liver Channel.Effect: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain；Hyperlipemia.Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving effect strengthens.For meat stagnation, dysentery is not well.Described in " book on Chinese herbal medicine is the newest ": control insufficiency of the spleen damp and hot, the mill that helps digestion is long-pending, profit defecation.
Flos Rosae Rugosae: for the dry flower of rosaceous plant Flos Rosae Rugosae Rosa rugosa Thunb..Nature and flavor: hardship sweet, micro-, temperature.Return liver, spleen channel.Effect: promoting QI circulation for relieving depression, and blood, pain relieving.For stomachache due to hyperactive liver-QI attacking the stomach, lack of appetite vomiting and nausea, menoxenia, fall and flutter the pain of injury.Described in " detailed outline is picked up any lost article from the road ": and blood, promoting the circulation of blood, regulate the flow of vital energy.Control migratory arthralgia.
The square solution of the present invention is: Fructus Amomi removing dampness appetizing, warming spleen and stopping diarrha, Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, Radix Aconiti Lateralis Preparata recuperating depleted YANG and rescuing the patient from collapse, mend fire supporing yang, Cortex Cinnamomi mends supporing yang, the promoting blood circulation to restore menstrual flow of fire, Rhizoma Alpiniae Officinarum warming stomach for dispelling cold, help digestion pain relieving, Lignum Aquilariae Resinatum promoting the circulation of QI to relieve pain, warming middle-JIAO improving inspiration by invigorating kidney-QI, the pleasant pain relieving of the Radix Linderae, warming kidney for dispelling cold, have that warming middle-JIAO is supporing yang, the effect of recuperating depleted YANG improving inspiration by invigorating kidney-QI.Chinese medicine is thought, primary disease is due to healthy energy virtual loss, blood stasis, the stagnation of QI, the cold coagulation numbness resistance heart arteries and veins turbid with expectorant that diet, feelings will, cold-evil etc. are caused, ictal feels oppressed with Danzhong or left chest, pain is as main clinical manifestation.So the basis that warming middle-JIAO is supporing yang, recuperating depleted YANG improving inspiration by invigorating kidney-QI is treatment hypertrophic obstructive cardiomyopathy, above seven flavor medicine is monarch drug, and the most fundamentally warming middle-JIAO is supporing yang, recuperating depleted YANG improving inspiration by invigorating kidney-QI, makes disease obtain basic control.Semen Persicae (parched) blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, Rhizoma Sparganii removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving, Rhizoma Curcumae circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving, Rhizoma Corydalis invigorates blood circulation promoting the circulation of QI, Oletum Trogopterori promoting blood circulation to remove blood stasis, worm removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones, Herba Artemisiae Anomalae removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling, ministerial drug in the above ten taste medicine sides of being, one side auxiliary monarch drug warming middle-JIAO is supporing yang, effect of recuperating depleted YANG improving inspiration by invigorating kidney-QI；On the other hand there is effect of promoting blood circulation to remove blood stasis, inducing menstruation to relieve menalgia as ministerial drug.Spina Gleditsiae detumescence poison holding, evacuation of pus parasite killing, Pericarpium Citri Reticulatae Viride is soothing the liver dispelling the stagnated QI, removing food stagnancyization are stagnant, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, Radix Aucklandiae promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, Fructus Toosendan soothing liver-QI circulation of qi promoting, pain relieving anthelmintic, Fructus Crataegi promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, Flos Rosae Rugosae promoting QI circulation for relieving depression, regulating blood flow to alleviate pains, above seven flavor medicine, as adjuvant drug, returns spleen, stomach warp, and improper diet addiction to greasy and sweet foods savoury or often heavy meal are excessive, with the passing of time impairing the spleen and stomach, transporting mistake department, makes humidogene expectorant, upper criminal ambition, clear sun is not opened up, functional activity of QI being not smooth, blockage of the cardiac vessels, then become primary disease.From pathology, treatment causes the inducement of hypertrophic obstructive cardiomyopathy, can promote that the warming middle-JIAO of the monarch and his subjects two medicine is supporing yang, effect of recuperating depleted YANG improving inspiration by invigorating kidney-QI as adjuvant drug, body promoting blood circulation to remove blood stasis, the effect of inducing menstruation to relieve menalgia can be promoted, simultaneously as the effect with strengthening the spleen to promote digestion by using corrigent the monarch and his subjects two medicine again.The all medicines of this side share, and the monarch and his subjects pull together, and minister assistant is altogether the most auxiliary, have that warming middle-JIAO is supporing yang, effect of recuperating depleted YANG improving inspiration by invigorating kidney-QI, promoting blood circulation to remove blood stasis, inducing menstruation to relieve menalgia, it is possible to effectively treat hypertrophic obstructive cardiomyopathy.
Another important feature of the present invention is that this Chinese medicine preparation contains abundant nutritional labeling, more than 17 kinds are had rich in aminoacid, wherein essential amino acid has threonine, valine, methionine, isoleucine, leucine, lysine and phenylalanine, trace element containing needed by human has ferrum, chromium, copper, boron, manganese, strontium and zinc, another calcic, potassium, magnesium, phosphorus several human body macroelement.Above nutritional labeling is all needed by human material, can effectively strengthen body immunity.
nullMedicine material consumption of the present invention is groped to sum up to draw through inventor in a large number，Each raw material dosage is for all having a preferable curative effect in following weight parts scope: Semen Persicae (parched) 10-14 part、Flos Carthami 7-11 part、Rhizoma Chuanxiong 18-22 part、Radix Salviae Miltiorrhizae 22-26 part、Spina Gleditsiae 18-22 part、Rhizoma Sparganii 13-17 part、Rhizoma Curcumae 13-17 part、Fructus Amomi 4-8 part、Rhizoma Zingiberis 13-17 part、Radix Aconiti Lateralis Preparata 8-12 part、Cortex Cinnamomi 4-8 part、Rhizoma Alpiniae Officinarum 16-20 part、Pericarpium Citri Reticulatae Viride 10-14 part、Pericarpium Citri Reticulatae 10-14 part、Radix Aucklandiae 8-12 part、Lignum Aquilariae Resinatum 4-8 part、Radix Linderae 7-11 part、Fructus Toosendan 13-17 part、Rhizoma Corydalis 18-22 part、Oletum Trogopterori 10-14 part、Worm 7-11 part、Herba Artemisiae Anomalae 18-22 part、Fructus Crataegi 18-22 part、Flos Rosae Rugosae 7-11 part.
Wherein it is preferably: Semen Persicae (parched) 12 parts, 9 parts of Flos Carthami, Rhizoma Chuanxiong 20 parts, Radix Salviae Miltiorrhizae 24 parts, Spina Gleditsiae 20 parts, Rhizoma Sparganii 15 parts, Rhizoma Curcumae 15 parts, Fructus Amomi 6 parts, Rhizoma Zingiberis 15 parts, Radix Aconiti Lateralis Preparata 10 parts, Cortex Cinnamomi 6 parts, Rhizoma Alpiniae Officinarum 18 parts, 12 parts of Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, the Radix Aucklandiae 10 parts, Lignum Aquilariae Resinatum 6 parts, the Radix Linderae 9 parts, Fructus Toosendan 15 parts, Rhizoma Corydalis 20 parts, Oletum Trogopterori 12 parts, worm 9 parts, Herba Artemisiae Anomalae 20 parts, Fructus Crataegi 20 parts, Flos Rosae Rugosae 9 parts.
The preparation method of a kind of Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy is as follows:
Step one: by weight of the present invention, takes Semen Persicae (parched), Fructus Crataegi, pulverizes, and crosses 200 mesh sieves, standby；
Step 2: by weight of the present invention, takes Radix Aconiti Lateralis Preparata, Fructus Toosendan, worm medical material are placed in marmite, add the water of 3 times of volumes, intense fire infusion 20-30 minute, fire infusion 30-40 minute of larding speech with literary allusions, filter liquor, repeatedly infusion three times, merge three filtrates, standby；
Step 3: by weight proportion of the present invention, take Radix Salviae Miltiorrhizae, Spina Gleditsiae, Rhizoma Sparganii, Rhizoma Curcumae, Rhizoma Zingiberis, Cortex Cinnamomi, Rhizoma Alpiniae Officinarum, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae, the Radix Aucklandiae, the Radix Linderae, Rhizoma Corydalis, Oletum Trogopterori, Herba Artemisiae Anomalae medical material are placed in marmite, add the water of 8 times of volumes, after intense fire infusion 20-30 minute, add Flos Carthami, Rhizoma Chuanxiong, Flos Rosae Rugosae and the Fructus Amomi tied with bundle respectively, Lignum Aquilariae Resinatum, intense fire infusion 10-20 minute, the fire infusion 30 ~ 40 minutes of larding speech with literary allusions filtrate, infusion merges gained filtrate for three times repeatedly, standby；
Step 4: combining step two, step 3 gained filtrate and with step one gained powder, mixing, stir evenly, both the decoction for the treatment of hypertrophic obstructive cardiomyopathy of the present invention.
Using method of the present invention: take decoction, take in meal one hour after, three times a day.
Medicine of the present invention has that warming middle-JIAO is supporing yang, the effect of recuperating depleted YANG improving inspiration by invigorating kidney-QI, promoting blood circulation to remove blood stasis, inducing menstruation to relieve menalgia, and good analgesic effect, cheap, having no side effect, easy to use, the mode that this Chinese medicine preparation uses treats the injury that can reduce Western medicine to patient body, alleviate the slight illness of patient, according to clinical 60 example patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 83.3%, two the course for the treatment of total effective rate 93.4%.
Detailed description of the invention
Embodiment one: Semen Persicae (parched) 12 parts, 9 parts of Flos Carthami, Rhizoma Chuanxiong 20 parts, Radix Salviae Miltiorrhizae 24 parts, Spina Gleditsiae 20 parts, Rhizoma Sparganii 15 parts, Rhizoma Curcumae 15 parts, Fructus Amomi 6 parts, Rhizoma Zingiberis 15 parts, Radix Aconiti Lateralis Preparata 10 parts, Cortex Cinnamomi 6 parts, Rhizoma Alpiniae Officinarum 18 parts, 12 parts of Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, the Radix Aucklandiae 10 parts, Lignum Aquilariae Resinatum 6 parts, the Radix Linderae 9 parts, Fructus Toosendan 15 parts, Rhizoma Corydalis 20 parts, Oletum Trogopterori 12 parts, worm 9 parts, Herba Artemisiae Anomalae 20 parts, Fructus Crataegi 20 parts, Flos Rosae Rugosae 9 parts.
Embodiment two: Semen Persicae (parched) 13 parts, 10 parts of Flos Carthami, Rhizoma Chuanxiong 21 parts, Radix Salviae Miltiorrhizae 23 parts, Spina Gleditsiae 21 parts, Rhizoma Sparganii 14 parts, Rhizoma Curcumae 16 parts, Fructus Amomi 7 parts, Rhizoma Zingiberis 14 parts, Radix Aconiti Lateralis Preparata 10 parts, Cortex Cinnamomi 7 parts, Rhizoma Alpiniae Officinarum 18 parts, 12 parts of Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, the Radix Aucklandiae 10 parts, Lignum Aquilariae Resinatum 6 parts, the Radix Linderae 9 parts, Fructus Toosendan 14 parts, Rhizoma Corydalis 21 parts, Oletum Trogopterori 13 parts, worm 8 parts, Herba Artemisiae Anomalae 21 parts, Fructus Crataegi 21 parts, Flos Rosae Rugosae 8 parts.
Embodiment three: Semen Persicae (parched) 14 parts, 8 parts of Flos Carthami, Rhizoma Chuanxiong 21 parts, Radix Salviae Miltiorrhizae 22 parts, Spina Gleditsiae 21 parts, Rhizoma Sparganii 14 parts, Rhizoma Curcumae 14 parts, Fructus Amomi 7 parts, Rhizoma Zingiberis 16 parts, Radix Aconiti Lateralis Preparata 11 parts, Cortex Cinnamomi 7 parts, Rhizoma Alpiniae Officinarum 19 parts, 11 parts of Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 11 parts, the Radix Aucklandiae 9 parts, Lignum Aquilariae Resinatum 7 parts, the Radix Linderae 8 parts, Fructus Toosendan 14 parts, Rhizoma Corydalis 21 parts, Oletum Trogopterori 12 parts, worm 10 parts, Herba Artemisiae Anomalae 21 parts, Fructus Crataegi 22 parts, Flos Rosae Rugosae 7 parts.
Patient is presented herein below and uses the clinical statistics data of medicine of the present invention:
One, physical data
Accept out-patient 60 example for medical treatment, patient is randomly divided into observation group and each 30 examples of matched group, wherein male 40 example, women 20 example, M-F 2:1, max age 26 years old, minimal ages 4 years old, course of disease some months to several years.Every basic documents such as two groups of patient ages, sex, courses of disease are essentially identical, no significant difference (P ＞ 0.05).
Two, diagnostic criteria
1, interventricular septal thickness >=18mm have Bicuspid valve systolic anterior motion, cardiac catheterization display left ventricular outflow tract pressure is poor
2, interventricular septal defect: systolic murmur position is close, but be full systole, apical region of heart is many without noise, and ultrasoundcardiogram, cardiac catheterization and angiocardiography can be distinguished.
3, aortic stenosis: symptom is similar with noise character, but noise position is higher, and Chang You arterial valve district systolic ejection sounds, the second sound weakens, it is also possible to have early diastolic murmur.X-ray shows that ascending aorta is expanded.Physiology action or medicine effect are little on noise impact.Before and after left heart catheterization display systole pressure differential is present in aortic valve.
Three, Therapeutic Method:
1, observation group is treated by invention implementation according to Medications Example one of the present invention, weighting raw materials, takes decoction, take, three times a day in meal one hour after.It within 7 days, it is a course for the treatment of.
2, matched group uses the treatment of conventional western medicine verapamil, within 7 days, is a course for the treatment of.
Four, efficacy assessment standard:
1, cure: cure: transference cure after treatment, heart failure is controlled, and podiod reduces.
2, take a turn for the better: after treatment, symptom takes a turn for the better, and heart failure is substantially controlled.
3, invalid: through treating more than 1 week, symptom is not all felt any better person.
Five, therapeutic outcome statistics:
Matched group result is added up
Use the Comparison of therapeutic situation of this Chinese medicine preparation two courses for the treatment of of two groups of patients
Wherein: total effective rate=cure rate+improvement rate
By contrasting the treatment total effective rate of two groups of patients it appeared that observation group is apparently higher than matched group, thus illustrate, Chinese medicine of the present invention has good clinical effectiveness on treatment hypertrophic obstructive cardiomyopathy, the cure rate for the treatment of can be effectively improved, effect is notable, cheap, have no adverse reaction and any toxic and side effects, there is wide market application foreground.
Model case and curative effect:
Case one, patient Wang, female, 16 years old, people from Qingdao City, comes here and goes to a doctor on January 20th, 2010.Main suit: the unclean sense of discomfort of left breast, even with cardiopalmus, breathe hard, hypopnea, even dyspnea with rapid and short breath, the terrified symptom such as uneasy, interval outbreak 4 years, have recently and increase the weight of trend.Go examination in hospital and do cardiac catheterization display left ventricular outflow tract pressure poor, by ultrasoundcardiogram, cardiac catheterization, be diagnosed as hypertrophic obstructive cardiomyopathy.Then here treatment, uses made preparation in the embodiment of the present invention one, and selected preparation method, after medication 5 days, and transference cure, recover good, continue medication 6 days, patient's malaise symptoms thoroughly disappears, and Effect of follow-up visit by telephone does not recurs half a year.
Case two, patient Lee, female, 12 years old, people from Linyi, Shandong.Come here on May 14th, 2010 to go to a doctor, main suit: Danzhong portion is ictal to feel oppressed, pain, be often accompanied by cardiopalmus, breathe hard, hypopnea, the malaise symptoms such as even dyspnea with rapid and short breath, pale complexion, cold spontaneous sweating, intermittent attack 5 years, have recently and increase the weight of trend.Go examination in hospital and do cardiac catheterization display left ventricular outflow tract pressure poor, by ultrasoundcardiogram, cardiac catheterization, be diagnosed as hypertrophic obstructive cardiomyopathy.Using made preparation in the embodiment of the present invention one, and selected preparation method, symptom goes down, and pain slightly alleviates, and after medication 7 days, pain disappears, and recovers good, continues medication 5 days, and symptom thoroughly disappears, and Effect of follow-up visit by telephone does not recurs half a year.

Claims (4)

  1. null1. the Chinese medicine preparation being used for treating hypertrophic obstructive cardiomyopathy，It is characterized in that，This Chinese medicine preparation is made up of the medicine of following weight portion: Semen Persicae (parched) 10-14 part、Flos Carthami 7-11 part、Rhizoma Chuanxiong 18-22 part、Radix Salviae Miltiorrhizae 22-26 part、Spina Gleditsiae 18-22 part、Rhizoma Sparganii 13-17 part、Rhizoma Curcumae 13-17 part、Fructus Amomi 4-8 part、Rhizoma Zingiberis 13-17 part、Radix Aconiti Lateralis Preparata 8-12 part、Cortex Cinnamomi 4-8 part、Rhizoma Alpiniae Officinarum 16-20 part、Pericarpium Citri Reticulatae Viride 10-14 part、Pericarpium Citri Reticulatae 10-14 part、Radix Aucklandiae 8-12 part、Lignum Aquilariae Resinatum 4-8 part、Radix Linderae 7-11 part、Fructus Toosendan 13-17 part、Rhizoma Corydalis 18-22 part、Oletum Trogopterori 10-14 part、Worm 7-11 part、Herba Artemisiae Anomalae 18-22 part、Fructus Crataegi 18-22 part、Flos Rosae Rugosae 7-11 part.
  2. Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy the most according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Semen Persicae (parched) 12 parts, 9 parts of Flos Carthami, Rhizoma Chuanxiong 20 parts, Radix Salviae Miltiorrhizae 24 parts, Spina Gleditsiae 20 parts, Rhizoma Sparganii 15 parts, Rhizoma Curcumae 15 parts, Fructus Amomi 6 parts, Rhizoma Zingiberis 15 parts, Radix Aconiti Lateralis Preparata 10 parts, Cortex Cinnamomi 6 parts, Rhizoma Alpiniae Officinarum 18 parts, 12 parts of Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 12 parts, the Radix Aucklandiae 10 parts, Lignum Aquilariae Resinatum 6 parts, the Radix Linderae 9 parts, Fructus Toosendan 15 parts, Rhizoma Corydalis 20 parts, Oletum Trogopterori 12 parts, worm 9 parts, Herba Artemisiae Anomalae 20 parts, Fructus Crataegi 20 parts, Flos Rosae Rugosae 9 parts.
  3. Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy the most according to claim 1 and 2, it is characterised in that: described Chinese medicine preparation is decoction.
  4. 4. the preparation method being used for treating the Chinese medicine preparation of hypertrophic obstructive cardiomyopathy, it is characterised in that preparation method is as follows: step one: by weight of the present invention, takes Semen Persicae (parched), Fructus Crataegi, pulverizes, crosses 200 mesh sieves, standby；Step 2: by weight of the present invention, takes Radix Aconiti Lateralis Preparata, Fructus Toosendan, worm medical material are placed in marmite, add the water of 3 times of volumes, intense fire infusion 20-30 minute, fire infusion 30-40 minute of larding speech with literary allusions, filter liquor, repeatedly infusion three times, merge three filtrates, standby；Step 3: by weight proportion of the present invention, take Radix Salviae Miltiorrhizae, Spina Gleditsiae, Rhizoma Sparganii, Rhizoma Curcumae, Rhizoma Zingiberis, Cortex Cinnamomi, Rhizoma Alpiniae Officinarum, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae, the Radix Aucklandiae, the Radix Linderae, Rhizoma Corydalis, Oletum Trogopterori, Herba Artemisiae Anomalae medical material are placed in marmite, add the water of 8 times of volumes, after intense fire infusion 20-30 minute, add Flos Carthami, Rhizoma Chuanxiong, Flos Rosae Rugosae and the Fructus Amomi tied with bundle respectively, Lignum Aquilariae Resinatum, intense fire infusion 10-20 minute, the fire infusion 30 ~ 40 minutes of larding speech with literary allusions filtrate, infusion merges gained filtrate for three times repeatedly, standby；Step 4: combining step two, step 3 gained filtrate and with step one gained powder, mixing, stir evenly, both the decoction for the treatment of hypertrophic obstructive cardiomyopathy of the present invention.
CN201610170825.7A 2016-03-24 2016-03-24 Traditional Chinese medicine preparation for treating hypertrophic obstructive cardiomyopathy and preparation method thereof Pending CN105816830A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1220892A (en) * 1998-10-29 1999-06-30 刘喜斌 Formula of Chinese medicine preparation for treating heart disease and preparation method thereof
CN101670060A (en) * 2009-10-15 2010-03-17 王峰 Traditional Chinese medicine composition for treating such diseases as hepatic stagnation, chest stuffiness and distension and preparation method
CN104258351A (en) * 2014-10-13 2015-01-07 张红梅 Traditional Chinese medicine preparation for treating alcoholic cardiomyopathy and preparation method of preparation
CN104784670A (en) * 2015-05-11 2015-07-22 郭延举 Pharmaceutical composition for treating myocarditis and preparation method of pharmaceutical composition
CN105056192A (en) * 2015-08-25 2015-11-18 崔新明 Traditional Chinese medicine composition for treating myocardial infarction and application thereof
CN105079674A (en) * 2015-09-10 2015-11-25 南京正亮医药科技有限公司 Medicinal preparation for treating chest stuffiness and pains
CN105106667A (en) * 2015-08-20 2015-12-02 登封市科创商务咨询有限公司 Decoction capable of removing blood stasis and arthritis

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1220892A (en) * 1998-10-29 1999-06-30 刘喜斌 Formula of Chinese medicine preparation for treating heart disease and preparation method thereof
CN101670060A (en) * 2009-10-15 2010-03-17 王峰 Traditional Chinese medicine composition for treating such diseases as hepatic stagnation, chest stuffiness and distension and preparation method
CN104258351A (en) * 2014-10-13 2015-01-07 张红梅 Traditional Chinese medicine preparation for treating alcoholic cardiomyopathy and preparation method of preparation
CN104784670A (en) * 2015-05-11 2015-07-22 郭延举 Pharmaceutical composition for treating myocarditis and preparation method of pharmaceutical composition
CN105106667A (en) * 2015-08-20 2015-12-02 登封市科创商务咨询有限公司 Decoction capable of removing blood stasis and arthritis
CN105056192A (en) * 2015-08-25 2015-11-18 崔新明 Traditional Chinese medicine composition for treating myocardial infarction and application thereof
CN105079674A (en) * 2015-09-10 2015-11-25 南京正亮医药科技有限公司 Medicinal preparation for treating chest stuffiness and pains

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李七一主编: "《中医疑难病证辨治与验案 难治性心脑血管病辨治与验案》", 28 February 2011 *

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