CN105596396A - Freshly squeezed artemisia apiacea vacuum-dried powder decoction pieces and preparation technology thereof - Google Patents
Freshly squeezed artemisia apiacea vacuum-dried powder decoction pieces and preparation technology thereof Download PDFInfo
- Publication number
- CN105596396A CN105596396A CN201610083523.6A CN201610083523A CN105596396A CN 105596396 A CN105596396 A CN 105596396A CN 201610083523 A CN201610083523 A CN 201610083523A CN 105596396 A CN105596396 A CN 105596396A
- Authority
- CN
- China
- Prior art keywords
- decoction pieces
- vacuum drying
- preparation technology
- sweet wormwood
- powder decoction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000005516 engineering process Methods 0.000 title claims abstract description 12
- 239000000843 powder Substances 0.000 title claims abstract description 12
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 241000049464 Artemisia apiacea Species 0.000 title abstract 5
- 235000011570 Artemisia caruifolia var apiacea Nutrition 0.000 title abstract 5
- 238000001291 vacuum drying Methods 0.000 claims abstract description 14
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 10
- 238000001914 filtration Methods 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 230000008901 benefit Effects 0.000 claims abstract description 5
- 238000003756 stirring Methods 0.000 claims abstract description 5
- 238000005406 washing Methods 0.000 claims abstract description 3
- 235000001405 Artemisia annua Nutrition 0.000 claims description 27
- 240000000011 Artemisia annua Species 0.000 claims description 27
- 238000002386 leaching Methods 0.000 claims description 8
- 238000003825 pressing Methods 0.000 claims description 2
- 238000009461 vacuum packaging Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 abstract description 8
- 239000004480 active ingredient Substances 0.000 abstract description 6
- 238000000034 method Methods 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 3
- 230000007012 clinical effect Effects 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 14
- 239000000047 product Substances 0.000 description 6
- 206010037660 Pyrexia Diseases 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 201000004792 malaria Diseases 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 240000001851 Artemisia dracunculus Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005200 bud stage Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000000192 social effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses freshly squeezed artemisia apiacea vacuum-dried powder decoction pieces and a preparation technology thereof. The technology comprises the following steps: collecting the medicinal material artemisia apiacea and selecting and drip-washing; squeezing when the artemisia apiacea is fresh, and filtering and fetching the juice; adding water into the residue and stirring; filtering and squeezing; and merging the obtained juice and performing decompressed concentration and vacuum drying. In the artemisia apiacea powder decoction pieces prepared by the method, polar and nonpolar active ingredients in the medicinal material are maintained to the greatest degree. The decoction pieces are convenient to store, transport and adjust, the quality is controllable, the curative effect is reliable, and the decoction pieces are of great significance to guaranteeing the clinical effect of traditional Chinese medicines. The popularization and implementation of the method bring remarkable social significance and economic benefits.
Description
Technical field
The invention belongs to Chinese medicine manufacture field, relate in particular to the processing technology of Chinese medicine sweet wormwood medicine materical crude slice.
Background technology
Chinese medicine sweet wormwood is the yellow wormwood artemisia of feverfewArtemisiaannuaL. dry aerial parts. This product is gathered in bud stage, has clearing away summerheat, except steaming, and effect of preventing malaria. Clinical summer-heat evil heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to yin labor heat, malaria fever and chills, the jaundice with damp-heat pathogen etc. of being usually used in.
The processing mode of conventional sweet wormwood medicine materical crude slice is: extract aerial part, chopping, dries and be used as medicine; Or after arranging, drying, packing storage and transport. These dry Artemisia annuas are transported to after prepared slices of Chinese crude drugs factory, need cleaning, vexed profit, section, and redry. Existing technique time and effort consuming, operation repeats, and has increased the production cost of medicine materical crude slice. In this process, not only can cause a large amount of losses of aqueous soluble active constituent wherein, and vexed profit operation is as carried out at high temperature season, medicinal material very easily occurs and go mouldy, thereby causes the decline of medical material quanlity and the reduction of clinical efficacy. This type of prepared herbal medicine in small pieces ready for decoction, bulky, easily to pollute and go mouldy, quality is difficult to ensure, is unfavorable for conditioning agent formulation and guarantees its clinical efficacy.
At present, on market, also there is the granule pieces that Artemisia annua is made after extracting to sell. In granule pieces preparation process, extract not only time consumption and energy consumption, and because conventional water does solvent, the nonpolar active ingredient in medicinal material is difficult to be extracted. In addition, be to be also dried and to pass through long-time storage owing to extracting the Artemisia annua of use, therefore, the loss of active ingredient is also very large. In order to ensure clinical effective, the steady quality of Artemisia annua, a kind of novel sweet wormwood medicine materical crude slice and preparation technology thereof urgently develop.
Summary of the invention
The present invention has announced " a kind of sweet wormwood fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof ". This technique can retain polarity and the nonpolar active ingredient in Artemisia annua to greatest extent, the loss of active ingredient and the decline of medical material quanlity of avoiding medicinal material to cause in existing medicine materical crude slice processing and storage and transport process, reduce the pollution that medicinal material is subject to mould etc., steady quality and the clinical safety of guaranteeing sweet wormwood medicine materical crude slice are effectively had great importance.
To achieve these goals, technical scheme of the present invention is:
Gather its aerial part picking time at sweet wormwood, clean, after washing, be cut into the long section of 1 ~ 5cm, take advantage of fresh squeezing, cross leaching juice with 80 ~ 200 eye mesh screens. The dregs of a decoction are added to the water of 1 ~ 3 times of amount, stir 5 ~ 30min, leave standstill after 30 ~ 120min, cross leaching juice with 80 ~ 200 eye mesh screens. By dregs pressing, cross leaching juice with 80 ~ 200 eye mesh screens.
The sweet wormwood juice of above-mentioned acquisition is merged to 40 ~ 65 DEG C of reduced pressure concentrations. The medicinal extract that concentrated gained relative density is 1.05 ~ 1.30 is dried 4 ~ 8 hours in 40 ~ 60 DEG C of vacuum drying chambers, and moisture is controlled in 12%. Dry thing was pulverized 60 ~ 100 mesh sieves, and vacuum packaging adds bagged dryer and antioxidant, obtained the fresh squeezing vacuum drying of sweet wormwood powder decoction pieces finished product.
On the label of product packaging bags, in printing the name of an article, medicinal part, planting site, manufacturer, date of manufacture, Contents of Main Components, meridian distribution of property and flavor, function cure mainly, the information such as usage and dosage, toxic and side effect and contraindication. In bag, enclose the thin layer of sweet wormwood and differentiate collection of illustrative plates and/or high efficiency liquid phase characteristic spectrum, as " identity card " of product. In addition, in the packaging bag of product, be printed on Quick Response Code, can link the information such as former plant photo, medicinal material photo, medicine materical crude slice photo, proterties and micro-diagnostic characteristics of obtaining product by scanning.
Usefulness of the present invention is:
The powder decoction pieces that directly segment squeezing after fresh Artemisia annua cleans and washs, filtration, reduced pressure concentration, vacuum drying obtain, can retain the active ingredient in medicinal material to greatest extent. This medicine materical crude slice volume compares to traditional medicine materical crude slice volume and reduces widely, and quality is more stable, is beneficial to accumulating and clinical adjustment, has very significant social effect and economic implications.
Detailed description of the invention
Embodiment 1
By the Artemisia annua of fresh collection, clean, with water wash, be cut into the long section of 2cm, take advantage of the squeezing of using fresh herb squeezer, with 100 eye mesh screens filtrations. The gained dregs of a decoction add the drinking water of 2 times of amounts, stir 20min, draw supernatant liquid filtering and obtain concoction after standing 30min. The dregs of a decoction squeeze with squeezer, leaching concoction. Filter by above-mentioned 3 times the sweet wormwood concoction obtaining and merge, reduced pressure concentration, Temperature Setting is 65 DEG C. Be 1.15 o'clock in concentrated gained medicinal extract relative density, transfer in vacuum drying chamber, in 60 DEG C dry 5 hours, moisture is not higher than 10%.
Embodiment 2
By the Artemisia annua of fresh collection, clean, with water wash, be cut into the long section of 5cm, take advantage of the squeezing of using fresh herb squeezer, with 80 eye mesh screens filtrations. The gained dregs of a decoction add the drinking water of 3 times of amounts, stir 30min, draw supernatant liquid filtering and obtain concoction after standing 60min. The dregs of a decoction squeeze with squeezer, leaching concoction. Filter by above-mentioned 3 times the sweet wormwood concoction obtaining and merge, reduced pressure concentration, Temperature Setting is 60 DEG C. Be 1.20 o'clock in concentrated gained medicinal extract relative density, transfer in vacuum drying chamber, in 60 DEG C dry 8 hours, moisture is not higher than 12%.
Above embodiment, is only the technological thought of explanation this invention, can not limit whereby the every technological thought proposing according to the present invention of protection scope of the present invention, and any change of doing on technical scheme basis, within all falling into the scope of protection of the invention.
Claims (4)
1. sweet wormwood fresh squeezing vacuum drying powder decoction pieces and a preparation technology thereof, is characterized in that: gather its aerial part picking time at sweet wormwood, clean, after washing, be cut into the long section of 1 ~ 5cm, take advantage of fresh squeezing, cross leaching juice with 80 ~ 200 eye mesh screens.
2. a kind of sweet wormwood fresh squeezing vacuum drying powder decoction pieces according to claim 1 and preparation technology thereof, it is characterized in that: the water that the dregs of a decoction in claim 1 is added to 1 ~ 3 times of amount, stir 5 ~ 30min, leave standstill after 30 ~ 120min, cross leaching juice with 80 ~ 200 eye mesh screens.
3. a kind of sweet wormwood fresh squeezing vacuum drying powder decoction pieces according to claim 1 and preparation technology thereof, is characterized in that: by the dregs pressing of gained in claim 2, cross leaching juice with 80 ~ 200 eye mesh screens.
4. a kind of sweet wormwood fresh squeezing vacuum drying powder decoction pieces according to claim 1 and preparation technology thereof, it is characterized in that: the juice of the filtration in right 1 ~ right 3 is merged, 40 ~ 65 DEG C of reduced pressure concentrations, gained relative density is that 1.05 ~ 1.30 medicinal extract was pulverized 60 ~ 100 mesh sieves in 40 ~ 60 DEG C of vacuum drying after 4 ~ 8 hours, vacuum packaging, obtains the fresh squeezing vacuum drying of sweet wormwood powder decoction pieces.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610083523.6A CN105596396A (en) | 2016-02-11 | 2016-02-11 | Freshly squeezed artemisia apiacea vacuum-dried powder decoction pieces and preparation technology thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610083523.6A CN105596396A (en) | 2016-02-11 | 2016-02-11 | Freshly squeezed artemisia apiacea vacuum-dried powder decoction pieces and preparation technology thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105596396A true CN105596396A (en) | 2016-05-25 |
Family
ID=55977131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610083523.6A Pending CN105596396A (en) | 2016-02-11 | 2016-02-11 | Freshly squeezed artemisia apiacea vacuum-dried powder decoction pieces and preparation technology thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105596396A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107095902A (en) * | 2017-06-22 | 2017-08-29 | 徐漫 | A kind of motherwort is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology |
| CN107260797A (en) * | 2017-06-18 | 2017-10-20 | 徐漫 | A kind of wrinkled giant hyssop is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology |
| CN107375390A (en) * | 2017-08-25 | 2017-11-24 | 徐自升 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood |
| CN107375353A (en) * | 2017-08-25 | 2017-11-24 | 徐自升 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lycopodium calvatum |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020094790A (en) * | 2001-06-13 | 2002-12-18 | (주)양지 | Functional jelly and method of preparation thereof |
| CN103408566A (en) * | 2013-07-17 | 2013-11-27 | 张家港威胜生物医药有限公司 | New artemisinin extraction process |
| CN105213451A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Taraxaci fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
-
2016
- 2016-02-11 CN CN201610083523.6A patent/CN105596396A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20020094790A (en) * | 2001-06-13 | 2002-12-18 | (주)양지 | Functional jelly and method of preparation thereof |
| CN103408566A (en) * | 2013-07-17 | 2013-11-27 | 张家港威胜生物医药有限公司 | New artemisinin extraction process |
| CN105213451A (en) * | 2015-11-14 | 2016-01-06 | 芜湖天成普阳中药科技有限公司 | A kind of Herba Taraxaci fresh squeezing vacuum drying powder decoction pieces and preparation technology thereof |
Non-Patent Citations (1)
| Title |
|---|
| 徐元贞等: "《中华方药宝典》", 31 March 2012, 河南科学技术出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107260797A (en) * | 2017-06-18 | 2017-10-20 | 徐漫 | A kind of wrinkled giant hyssop is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology |
| CN107095902A (en) * | 2017-06-22 | 2017-08-29 | 徐漫 | A kind of motherwort is fresh to squeeze vacuum drying powder decoction pieces and its preparation technology |
| CN107375390A (en) * | 2017-08-25 | 2017-11-24 | 徐自升 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of oriental wormwood |
| CN107375353A (en) * | 2017-08-25 | 2017-11-24 | 徐自升 | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of lycopodium calvatum |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107412303A (en) | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eupatorium | |
| CN107582624A (en) | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of Pogostemon cablin | |
| CN107281247A (en) | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of eclipta | |
| CN105193894A (en) | Freshly squeezed vacuum drying cholla stem powdery decoction pieces and preparation process thereof | |
| CN105687280A (en) | Freshly-squeezed freeze-dried Artemisia annua powder decoction pieces and preparation technology thereof | |
| CN105596396A (en) | Freshly squeezed artemisia apiacea vacuum-dried powder decoction pieces and preparation technology thereof | |
| CN105232607A (en) | Cactus freshly-squeezed spray dried granule decoction piece and preparation process thereof | |
| CN105998395A (en) | Herba Verbenae freshly squeezed freeze drying powder decoction piece and preparation technology thereof | |
| CN107441223A (en) | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of cordate houttuynia | |
| CN105641013A (en) | Freshly-squeezed and spray-dried sweet wormwood decoction powder and preparation technology thereof | |
| CN107362180A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of lycopodium calvatum | |
| CN107397787A (en) | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of Pogostemon cablin | |
| CN107485633A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of folium artemisiae argyi | |
| CN107375394A (en) | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of fringed pink | |
| CN107397789A (en) | A kind of schizonepeta is fresh to squeeze spray-dried powders medicine materical crude slice and its preparation technology | |
| CN107375529A (en) | A kind of fresh preparation technology for squeezing spray-dried granules medicine materical crude slice of bittersweet | |
| CN107441154A (en) | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of Pogostemon cablin | |
| CN107412301A (en) | A kind of fresh preparation technology for squeezing vacuum drying powder decoction pieces of eclipta | |
| CN107485640A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of Herba Lycopi | |
| CN107412304A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of eclipta | |
| CN107320567A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of bittersweet | |
| CN107412302A (en) | A kind of fresh preparation technology for squeezing freeze-dried powder medicine materical crude slice of eclipta | |
| CN107375418A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of elscholtiza | |
| CN107213186A (en) | A kind of acalypha copperleaf is fresh to squeeze spray-dried granules medicine materical crude slice and its preparation technology | |
| CN107441233A (en) | A kind of fresh preparation technology for squeezing spray-dried powders medicine materical crude slice of black nightshade |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160525 |