CN105559060A - Spleen-benefiting and stomach-invigorating globefish oil health capsule - Google Patents

Spleen-benefiting and stomach-invigorating globefish oil health capsule Download PDF

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Publication number
CN105559060A
CN105559060A CN201510951355.3A CN201510951355A CN105559060A CN 105559060 A CN105559060 A CN 105559060A CN 201510951355 A CN201510951355 A CN 201510951355A CN 105559060 A CN105559060 A CN 105559060A
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parts
capsule
globefish
fish oil
stomach
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CN201510951355.3A
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CN105559060B (en
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徐伦超
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Great Marine Health Food Co Ltd In Qingdao
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Great Marine Health Food Co Ltd In Qingdao
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a spleen-benefiting and stomach-invigorating globefish oil health capsule. Raw materials such as globefish oil, Chinese yam, bighead atractylodes rhizome, hawthorns, scutellaria baicalensis, red ginseng and liquorice are scientifically combined, a formula that 3-5 parts of globefish oil, 10-15 parts of Chinese yam, 8-15 parts of bighead atractylodes rhizome, 10-15 parts of hawthorns, 3-5 parts of scutellaria baicalensis, 2-3 parts of red ginseng and 1 part of liquorice is obtained through optimization, and then the spleen-benefiting and stomach-invigorating globefish oil health capsule is prepared according to the processes of blending, mixing, ultrasonic-assisted enzymolysis, filtering, concentrating, compounding, drying, sterilizing and capsule filling. The spleen-benefiting and stomach-invigorating globefish oil health capsule product has the advantages that immunological functional activity can be effectively enhanced by virtue of synergistic effect between the globefish oil and Chinese herbal medicines, gastroenteric function of people can be comprehensively regulated, vitality of stomach can be improved, in vivo environment can be managed, in vivo waste can be discharged, free radicals can be eliminated, and the spleen-benefiting and stomach-invigorating globefish oil health capsule is safe, has no side effect, is easy to eat and has a relatively good market application prospect.

Description

A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule
Technical field
The present invention relates to a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, particularly a kind of health-caring capsule made for raw material with filefish fish oil and vegetable Chinese herbal medicine, belong to field of health care food.
Background technology
Containing extremely toxic substance tetrodotoxin in globe fish (Fugurubripes), this toxin has high economic worth and medical value.People comparatively go deep into %, careful to the research of tetrodotoxin, but have ignored the value of globe fish other side.Along with non-toxic globefish cultivation and the development of processing detoxification technology, the output of China's non-toxic globefish rises year by year, year outlet rate more than 90%, has now become the main source of external globe fish supply.Identify through State Aquatic Product Quality Monitoring Test Centre: the protein content of filefish is up to 17.71%, and fat content is only 0.62%, unsaturated fatty acid content more than 20%, the wherein main component of DHA(docosapentaenoic acid) to account for 15.36%, EPA be 6.19%.Filefish fish oil mainly refers to the extract from the leftover bits and pieces such as filefish liver, ovary after detoxification, has tumor suppression, develop immunitypty, the various addictive function of withdrawal, is usually used in food, health products, medicine etc. at present, has good application and development and is worth.
Quickening, irregular, the quick food of living of rhythm of life, drinking beyond one's capacity etc. makes the increasing crowd of China occur jeopardizing the inferior health illness such as increasing disorder of function of stomach, gasteremphraxis, hydrochloric acid in gastric juice, stomachache the healthy of people, affect quality of life.Along with the continuous enhancing of people's prevention and health care consciousness, society increases day by day to the demand with immunological regulation efficiency health-care food.Chinese herbal medicine resource is the rarity of Chinese traditional culture, because of its effect significantly, green, safely, have no side effect, the application in field of health care food is further extensive.Result of study shows, the health products utilizing Chinese herbal medicine to develop contain abundant nutritional labeling, be rich in trace element, the vitamin isoreactivity nutritional labelings such as polysaccharide, flavones, amino acid, potassium calcium, there is adjustment function of human body, the effect such as improve stomach function, develop immunitypty, nourishing and fit keeping function, promote longevity.
At present, also there is more drawback in the application in field of health care food of filefish fish oil and Chinese herbal medicine, is difficult to the health-care efficacy really playing filefish fish oil and Chinese herbal medicine.The present invention is directed to the problems referred to above, develop a kind of health-caring capsule with stomach invigorating effect utilizing filefish fish oil and composite Chinese herbal, meet the demand of market to stomach-invigoratinghealth health care food.
Summary of the invention
For overcoming the deficiencies in the prior art, the object of the present invention is to provide a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, this health-caring capsule has beneficial spleen stomach invigorating, strengthens stomach function, improves the effects such as body immunity.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The invention provides a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is characterized in that health-caring capsule raw material composition and quality proportioning are: 3 ~ 5 parts, filefish fish oil, Chinese yam 10 ~ 15 parts, the bighead atractylodes rhizome 8 ~ 10 parts, hawthorn 10 ~ 15 parts, the root of large-flowered skullcap 3 ~ 5 parts, red ginseng 2 ~ 3 parts, 1 part, Radix Glycyrrhizae.
The preferred technical solution of the present invention is: a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, is characterized in that: it is characterized in that health-caring capsule raw material composition and quality proportioning are: 4 parts, filefish fish oil, Chinese yam 12 parts, the bighead atractylodes rhizome 9 parts, hawthorn 12 parts, the root of large-flowered skullcap 4 parts, red ginseng 2.5 parts, 1 part, Radix Glycyrrhizae.
The invention provides a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is characterized in that being prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) pulverize: respectively the bighead atractylodes rhizome, the root of large-flowered skullcap, red ginseng, Radix Glycyrrhizae superminiature pulverizer are pulverized, cross 100 mesh sieves; The refiner homogenate of Chinese yam, hawthorn;
(3) allotment is weighed: allocated according to aforementioned proportion by each raw material;
(4) homogenate: mixed by the raw material except filefish fish oil, adds the pure water of the rear material 20 times of mass ratioes of mixing;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 3 ~ 5% amylase, 1 ~ 2% cellulase, 1 ~ 2% pectase, under ultrasonic assistant action condition, 40 ~ 60 DEG C of enzymolysis 3 ~ 5h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) composite: by filefish fish oil with concentrated after extract mix;
(9) drying and crushing: crushed after being dried, crosses 200 mesh sieves;
(10) sterilizing: with cobalt-60 sterilizing;
(11) filling capsule: filling at indoor No. 0 capsule of cleaning;
(12) shaped article: bottled by the capsule after filling, labeling, namely coding obtains the filefish fish oil health-caring capsule with stomach invigorating effect.
The invention provides a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, carried out toxicology test and the safety evaluatio of health-caring capsule by animal experiment.Chmice acute Oral toxicity result of the test shows, this health-caring capsule is greater than high dose group 75mg/kgbw to chmice acute per os maximum tolerated dose; Genetic toxicity test mouse marrow cell micro nuclear test and mouse inbred strain two result of the tests are feminine gender, show that this health-caring capsule is without mutagenesis; From rat 30d feeding trial, the behavior of rat sign is normal, figure is healthy, blood and blood parameters also change without exception, and therefore the dosage (150 times of human body recommended amounts) of 75mg/kgbw belongs to safe dose; Genetic toxicity test and rat 30d feeding trial result are feminine gender, therefore determine that this health-caring capsule belongs to non-toxic type food, and people can be safe relieved edible.
The invention provides a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is advantageous that scientific compatibility filefish fish oil and multiple Chinese herbal medicine, immunologic function activity can be effectively strengthened by the synergy between filefish fish oil and Chinese herbal medicine, the each organ function of comprehensive adjustment human body, particularly stomach invigorating effect, administers vivo environment, discharge rubbish in body, eliminate free radical, safety has no side effect, instant.Different Chinese herbal medicine nature and flavor are different, effect also exists huge difference, complicated interaction relationship is there is after different Chinese herbal medicine combinations, and proportioning between Chinese herbal medicine is closer, different ratio also will make monarch relation that substantial change occurs, thus make the relation generation material alterations of composite Chinese herbal.The application is by filefish fish oil and Chinese yam, the bighead atractylodes rhizome, hawthorn, the root of large-flowered skullcap, there is complicated interaction relationship to each other in the Chinese herbal medicines such as red ginseng, rational proportion, by the enzymolysis of the complex enzyme formulation under ultrasonic assistant condition, active component in filefish fish oil and Chinese herbal medicine is fully utilized, achieve unforeseeable technique effect, make the relation generation material alterations of health-caring capsule, the TAC of the application's health-caring capsule reaches 585.22 ± 42.14U/mL, there is good immunoregulatory activity, mouse test results shows that health-caring capsule has significant stomach invigorating effect, in addition, result of the test shows that change health-caring capsule raw material composition or proportioning can reduce the oxidation resistance (P<0.01) of health-caring capsule, illustrates that the synergy between filefish fish oil and Chinese herbal medicine serves the effect significantly promoting health-caring capsule functional activity.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) pulverize: respectively the bighead atractylodes rhizome, the root of large-flowered skullcap, red ginseng, Radix Glycyrrhizae superminiature pulverizer are pulverized, cross 100 mesh sieves; The refiner homogenate of Chinese yam, hawthorn;
(3) allotment is weighed: by each raw material according to 4 parts, filefish fish oil, Chinese yam 12 parts, the bighead atractylodes rhizome 9 parts, hawthorn 12 parts, the root of large-flowered skullcap 4 parts, red ginseng 2.5 parts, Radix Glycyrrhizae 1 part of ratio allotment;
(4) homogenate: mixed by the raw material except filefish fish oil, adds the pure water of the rear material 20 times of mass ratioes of mixing;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 4% amylase, 1.5% cellulase, 1.5% pectase, under ultrasonic assistant action condition, 40 ~ 60 DEG C of enzymolysis 4h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) composite: by filefish fish oil with concentrated after extract mix;
(9) drying and crushing: crushed after being dried, crosses 200 mesh sieves;
(10) sterilizing: with cobalt-60 sterilizing;
(11) filling capsule: filling at indoor No. 0 capsule of cleaning;
(12) shaped article: bottled by the capsule after filling, labeling, namely coding obtains the filefish fish oil health-caring capsule with stomach invigorating effect.
Embodiment 2:
A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) pulverize: respectively the bighead atractylodes rhizome, the root of large-flowered skullcap, red ginseng, Radix Glycyrrhizae superminiature pulverizer are pulverized, cross 100 mesh sieves; The refiner homogenate of Chinese yam, hawthorn;
(3) allotment is weighed: by each raw material according to 5 parts, filefish fish oil, Chinese yam 10 parts, the bighead atractylodes rhizome 10 parts, hawthorn 10 parts, the root of large-flowered skullcap 5 parts, red ginseng 2 parts, Radix Glycyrrhizae 1 part of ratio allotment;
(4) homogenate: mixed by the raw material except filefish fish oil, adds the pure water of the rear material 20 times of mass ratioes of mixing;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 5% amylase, 2% cellulase, 2% pectase, under ultrasonic assistant action condition, 40 ~ 60 DEG C of enzymolysis 3h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) composite: by filefish fish oil with concentrated after extract mix;
(9) drying and crushing: crushed after being dried, crosses 200 mesh sieves;
(10) sterilizing: with cobalt-60 sterilizing;
(11) filling capsule: filling at indoor No. 0 capsule of cleaning;
(12) shaped article: bottled by the capsule after filling, labeling, namely coding obtains the filefish fish oil health-caring capsule with stomach invigorating effect.
Embodiment 3:
A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) pulverize: respectively the bighead atractylodes rhizome, the root of large-flowered skullcap, red ginseng, Radix Glycyrrhizae superminiature pulverizer are pulverized, cross 100 mesh sieves; The refiner homogenate of Chinese yam, hawthorn;
(3) allotment is weighed: by each raw material according to 3 parts, filefish fish oil, Chinese yam 15 parts, the bighead atractylodes rhizome 8 parts, hawthorn 15 parts, the root of large-flowered skullcap 3 parts, red ginseng 3 parts, Radix Glycyrrhizae 1 part of ratio allotment;
(4) homogenate: mixed by the raw material except filefish fish oil, adds the pure water of the rear material 20 times of mass ratioes of mixing;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 3% amylase, 1% cellulase, 1% pectase, under ultrasonic assistant action condition, 40 ~ 60 DEG C of enzymolysis 5h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) composite: by filefish fish oil with concentrated after extract mix;
(9) drying and crushing: crushed after being dried, crosses 200 mesh sieves;
(10) sterilizing: with cobalt-60 sterilizing;
(11) filling capsule: filling at indoor No. 0 capsule of cleaning;
(12) shaped article: bottled by the capsule after filling, labeling, namely coding obtains the filefish fish oil health-caring capsule with stomach invigorating effect.
Above embodiment only for illustration of technical scheme of the present invention, but not is limited; Although be described in detail by invention with reference to previous embodiment, for the person of ordinary skill of the art, still the technical scheme described in previous embodiment can be modified, or equivalent replacement has been carried out to wherein portion of techniques feature; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.

Claims (1)

1. a beneficial spleen stomach invigorating filefish fish oil health-caring capsule, prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) pulverize: respectively the bighead atractylodes rhizome, the root of large-flowered skullcap, red ginseng, Radix Glycyrrhizae superminiature pulverizer are pulverized, cross 100 mesh sieves; The refiner homogenate of Chinese yam, hawthorn;
(3) allotment is weighed: by each raw material according to 3 ~ 5 parts, filefish fish oil, Chinese yam 10 ~ 15 parts, the bighead atractylodes rhizome 8 ~ 10 parts, hawthorn 10 ~ 15 parts, the root of large-flowered skullcap 3 ~ 5 parts, red ginseng 2 ~ 3 parts, Radix Glycyrrhizae 1 part of ratio allotment;
(4) homogenate: mixed by the raw material except filefish fish oil, adds the pure water of the rear material 20 times of mass ratioes of mixing;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 3 ~ 5% amylase, 1 ~ 2% cellulase, 1 ~ 2% pectase, under ultrasonic assistant action condition, 40 ~ 60 DEG C of enzymolysis 3 ~ 5h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) composite: by filefish fish oil with concentrated after extract mix;
(9) drying and crushing: crushed after being dried, crosses 200 mesh sieves;
(10) sterilizing: with cobalt-60 sterilizing;
(11) filling capsule: filling at indoor No. 0 capsule of cleaning;
(12) shaped article: bottled by the capsule after filling, labeling, namely coding obtains the filefish fish oil health-caring capsule with stomach invigorating effect.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111011852A (en) * 2019-12-26 2020-04-17 吉林大学 Preparation method of ginseng instant food with liver protection function

Citations (9)

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Publication number Priority date Publication date Assignee Title
CN1279957A (en) * 2000-03-06 2001-01-17 辽阳鸿宇制药有限公司 Use of puffer liver oil in preparing food for curing poisonous drug dependence
CN1895285A (en) * 2006-06-29 2007-01-17 董玉明 Medicinal use of fugu cod liver oil
CN101066340A (en) * 2007-05-16 2007-11-07 苏振芳 Compound externally applied tetrodotoxin ointment and its prepn
CN101182448A (en) * 2007-11-23 2008-05-21 大连工业大学 Method for preparing non-toxic globefish fin wine
CN101279037A (en) * 2007-04-03 2008-10-08 北京亚东生物制药有限公司 Composition for curing impairment by overeating, preparation and quality control method
KR101002051B1 (en) * 2003-08-14 2010-12-17 포항공과대학교 산학협력단 A method for producing a functional food material from a puffer by using batch distillation
CN103977338A (en) * 2014-06-04 2014-08-13 天津太平洋制药有限公司 Traditional Chinese medicine for strengthening spleen and stomach
JP5663523B2 (en) * 2012-04-27 2015-02-04 株式会社萬坊 Method for producing pufferfish liver oil
CN104434982A (en) * 2015-01-06 2015-03-25 刘学民 Medicinal globefish oil making method

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279957A (en) * 2000-03-06 2001-01-17 辽阳鸿宇制药有限公司 Use of puffer liver oil in preparing food for curing poisonous drug dependence
KR101002051B1 (en) * 2003-08-14 2010-12-17 포항공과대학교 산학협력단 A method for producing a functional food material from a puffer by using batch distillation
CN1895285A (en) * 2006-06-29 2007-01-17 董玉明 Medicinal use of fugu cod liver oil
CN101279037A (en) * 2007-04-03 2008-10-08 北京亚东生物制药有限公司 Composition for curing impairment by overeating, preparation and quality control method
CN101066340A (en) * 2007-05-16 2007-11-07 苏振芳 Compound externally applied tetrodotoxin ointment and its prepn
CN101182448A (en) * 2007-11-23 2008-05-21 大连工业大学 Method for preparing non-toxic globefish fin wine
JP5663523B2 (en) * 2012-04-27 2015-02-04 株式会社萬坊 Method for producing pufferfish liver oil
CN103977338A (en) * 2014-06-04 2014-08-13 天津太平洋制药有限公司 Traditional Chinese medicine for strengthening spleen and stomach
CN104434982A (en) * 2015-01-06 2015-03-25 刘学民 Medicinal globefish oil making method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111011852A (en) * 2019-12-26 2020-04-17 吉林大学 Preparation method of ginseng instant food with liver protection function

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