CN104877882A - Astaxanthin composite mixed liquor with blood glucose reducing function - Google Patents
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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Abstract
The invention discloses astaxanthin composite mixed liquor with a blood glucose reducing function. The astaxanthin composite mixed liquor is prepared from astaxanthin and Chinese herbal medicine raw materials through scientific compatibility and preferably comprises, by weight, 10-20 parts of astaxanthin, 15-20 parts of medlar, 10-15 parts of common yam rhizome, 10-20 parts of schisandra chinensis, 5-10 parts of polygonum multiflorum, 10-15 parts of coix seeds, 5-8 parts of ligusticum wallichii, 3-5 parts of cistanche, 3-5 parts of roots of kudzu vine, 4-6 parts of dogwood, 2-3 parts of cortex moutan, 3-5 parts of liquorice and 3-5 parts of stevia rebaudiana, and the astaxanthin composite mixed liquor is prepared through the technologies of leaching, extracting, mixing, blending, filling and sterilizing. The astaxanthin composite mixed liquor has the advantages of having remarkable functions of reducing blood glucose, tonifying qi and the body, supporting the healthy energy, resisting fatigue, prolonging life and the like by means of the synergistic effect among the astaxanthin and Chinese herbal medicines and being safe, free from side effects and convenient to eat and has good market application prospects.
Description
Technical field
The present invention relates to a kind of astaxanthin compound assembled alcoholic drinks with effect of lowering blood sugar, particularly a kind of astaxanthin compound assembled alcoholic drinks made for raw material with astaxanthin and vegetable Chinese herbal medicine, belong to field of health care food.
Background technology
Astaxanthin (astaxanthin), also known as " ASX ", is a kind of Red carotenoids found from shrimp crab shell, oyster, salmon and algae, fungi.There are some researches show in recent years, natural astaxanthin has stronger anti-oxidant activity, has scavenging free radicals, protection blood vessel, reduction cholesterol, skin care, vision protection, neuroprotective system, prevention senile dementia, alleviates many-sided health protection effect such as arthralgia; Particularly natural astaxanthin has strong anti-oxidant activity, is called as " supper vitamin E ", " super antioxidant ".A large amount of human trial of natural astaxanthin and animal experiment verified it be a kind of very safe carotenoid.In Japan, natural astaxanthin also for food and animal-feed, U.S. FDA, European Union, Canadian food surveillance office also approved it as the fodder additives of salmon class.Because it has multiple biological effect, the application in nutrition and medicine has vast potential for future development, and particularly astaxanthin has boundless application prospect as the high-class healthy food of the mankind.
The metabolism syndrome of diabetes (diadetes mellitus) to be one group with long term hyperglycemia be principal character, it be due to insulin deficit and or biological insulin effect obstacle cause carbohydrate metabolism disturbance, simultaneously with fat, protein, water and eletrolytes metabolic disturbance, can concurrent eye, kidney, nerve, the multiple organ such as cardiovascular chronic injury.Its morbidity is just along with the improve of living standards of the people, and the aging of population, living-pattern preservation and increasing sharply, has become the third-largest Non Communicable Diseases (NCD) after cardiovascular diseases and tumour, brings white elephant to society and economy.Due to the cause of disease of diabetes and pathogenesis not yet fully clear, also do not have a kind of medicine to cure diabetes at present, patient need take medicine maintenance blood glucose balance all the life.Recent two decades comes, and protective foods development is very swift and violent, is valued by the people gradually.The protective foods with auxiliary hyperglycemic function is very useful to the improvement of quality of life in patients with diabetes, is subject to the favor of more and more patient.
Chinese herbal medicine resource is the rarity of Chinese traditional culture, because of its effect significantly, green, safely, have no side effect, the application in field of health care food is further extensive.Result of study shows, the healthcare products utilizing herbal medicine to develop contain abundant nutritive ingredient, not only remain trace element, the VITAMIN isoreactivity nutritive ingredients such as original polysaccharide in herbal medicine, flavones, amino acid, potassium calcium, and create the nutritive ingredients such as a large amount of sugar, protein, essential amino acid in process of production, long-term rationally ediblely function of human body can be regulated, strengthening immunity, nourishing and fit keeping function, the effect such as to promote longevity.Herbal medicine is by increasing for prevention and therapy diabetes in recent years, but its effect needs further lifting badly.
At present, also there is more drawback in the application of herbal medicine in field of health care food, is difficult to the health-care effect really playing herbal medicine.The present invention is directed to the problems referred to above, develop a kind of astaxanthin compound assembled alcoholic drinks with effect of lowering blood sugar utilizing astaxanthin and composite Chinese herbal, meet the demand of market to marine health product and herbal health care food.
Summary of the invention
For overcoming the deficiencies in the prior art, the object of the present invention is to provide a kind of astaxanthin compound assembled alcoholic drinks with effect of lowering blood sugar, this astaxanthin compound assembled alcoholic drinks has hypoglycemic, tonifying Qi help, strengthens the body resistance to consolidate the constitution, antifatigue, the effect such as to promote longevity, meet increasing diabetic subject to efficient, safety, harmless health-caring product capable of reducing blood sugar demand.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The invention provides a kind of astaxanthin compound assembled alcoholic drinks with effect of lowering blood sugar, it is characterized in that astaxanthin compound assembled alcoholic drinks raw material composition and quality proportioning are: astaxanthin 10 ~ 20 parts, matrimony vine 15 ~ 20 parts, Rhizoma dioscoreae 10 ~ 15 parts, 10 ~ 20 parts, shizandra berry, Tuber Fleeceflower Root 5 ~ 10 parts, Semen Coicis 10 ~ 15 parts, Ligusticum wallichii 5 ~ 8 parts, Herba Cistanches 3 ~ 5 parts, the root of kudzu vine 3 ~ 5 parts, skunk bush 4 ~ 6 parts, the root bark of tree peony 2 ~ 3 parts, 3 ~ 5 parts, Radix Glycyrrhizae, sweet Stevia 3 ~ 5 parts.
The preferred technical solution of the present invention is: a kind of astaxanthin compound assembled alcoholic drinks with effect of lowering blood sugar, is characterized in that: it is characterized in that astaxanthin compound assembled alcoholic drinks raw material composition and quality proportioning are: astaxanthin 15 parts, matrimony vine 18 parts, Rhizoma dioscoreae 12 parts, 15 parts, shizandra berry, Tuber Fleeceflower Root 8 parts, Semen Coicis 12 parts, Ligusticum wallichii 6 parts, Herba Cistanches 4 parts, the root of kudzu vine 4 parts, skunk bush 5 parts, the root bark of tree peony 2.5 parts, 4 parts, Radix Glycyrrhizae, sweet Stevia 4 parts.
The invention provides a kind of astaxanthin compound assembled alcoholic drinks with effect of lowering blood sugar, it is characterized in that being prepared by following steps:
(1) herbal medicine pre-treatment: adopt pollution-free, pure herbal raw material, dries with pure water cleaning;
(2) pulverize: by matrimony vine, Rhizoma dioscoreae tissue mashing crusher machine; All the other herbal medicine cross 200 mesh sieves after pulverizing;
(3) coordinate: in proportion herbal medicine is coordinated;
(4) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 10 times, hot digestion 30 ~ 60min;
(5) filter: filter, obtain Chinese herbal medicine leaching liquor;
(6) composite: in Chinese herbal medicine leaching liquor, to add astaxanthin in proportion;
(7) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging;
(8) allocate: allocate with anhydrous edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(9) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(10) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining astaxanthin compound assembled alcoholic drinks.
The invention provides a kind of astaxanthin compound assembled alcoholic drinks with effect of lowering blood sugar, carried out toxicology test and the safety evaluation of astaxanthin compound assembled alcoholic drinks by animal experiment.Chmice acute Oral toxicity test-results shows, this astaxanthin compound assembled alcoholic drinks is greater than high dose group 75mg/kgbw to chmice acute per os maximum tolerated dose; Genetic toxicity test mouse marrow cell micro nuclear test and mouse inbred strain two test-results are feminine gender, show that this astaxanthin compound assembled alcoholic drinks is without mutagenesis; From rat 30d feeding study, the behavior of rat sign is normal, figure is healthy, blood and blood parameters also change without exception, and therefore the dosage (150 times of human body recommended amounts) of 75mg/kgbw belongs to safe dose; Genetic toxicity test and rat 30d feeding study result are feminine gender, therefore determine that this astaxanthin compound assembled alcoholic drinks belongs to non-toxic type food, and people can be safe relieved edible.
The invention provides a kind of astaxanthin compound assembled alcoholic drinks with effect of lowering blood sugar, it is advantageous that scientific compatibility astaxanthin and multiple herbal medicine, by the synergy between astaxanthin and herbal medicine can effectively hypoglycemic, tonifying Qi help, strengthen the body resistance to consolidate the constitution, antifatigue, the effect such as to promote longevity, safety has no side effect, instant.Different herbal medicine nature and flavor are different, effect also exists huge difference, complicated interaction relationship is there is after different herbal medicine combinations, and proportioning between herbal medicine is closer, different ratio also will make monarch relation that substantial change occurs, thus make the relation generation material alterations of composite Chinese herbal.Complicated interaction relationship is there is to each other in the application by herbal medicine such as astaxanthin and matrimony vine, Rhizoma dioscoreae, shizandra berry, Tuber Fleeceflower Root, Semen Coicis, Ligusticum wallichii, Herba Cistanches, the root of kudzu vine, skunk bush, the root bark of tree peony, Radix Glycyrrhizae, sweet Stevia, rational proportion, achieve unforeseeable technique effect, make the relation generation material alterations of astaxanthin compound assembled alcoholic drinks, the modeling test group of this astaxanthin compound of feeding assembled alcoholic drinks after three weeks blood-sugar content compared with control group declines 49.85%, illustrates that product has good hypoglycemic activity; And test-results shows that change astaxanthin compound assembled alcoholic drinks raw material composition or proportioning can reduce the hypoglycemic ability (P<0.01) of astaxanthin compound assembled alcoholic drinks, illustrates that the synergy between astaxanthin and herbal medicine serves the effect significantly promoting astaxanthin compound assembled alcoholic drinks functionally active.
Embodiment
below in conjunction with embodiment, the present invention will be further described.
embodiment 1:
There is an astaxanthin compound assembled alcoholic drinks for effect of lowering blood sugar, prepared by following steps:
(1) herbal medicine pre-treatment: adopt pollution-free, pure herbal raw material, dries with pure water cleaning;
(2) pulverize: by matrimony vine, Rhizoma dioscoreae tissue mashing crusher machine; All the other herbal medicine cross 200 mesh sieves after pulverizing;
(3) coordinate: in matrimony vine 18 parts, Rhizoma dioscoreae 12 parts, 15 parts, shizandra berry, Tuber Fleeceflower Root 8 parts, Semen Coicis 12 parts, Ligusticum wallichii 6 parts, Herba Cistanches 4 parts, the root of kudzu vine 4 parts, skunk bush 5 parts, the root bark of tree peony 2.5 parts, 4 parts, Radix Glycyrrhizae, sweet Stevia 4 parts of ratios, herbal medicine is coordinated;
(4) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 10 times, hot digestion 30 ~ 60min;
(5) filter: filter, obtain Chinese herbal medicine leaching liquor;
(6) composite: in Chinese herbal medicine leaching liquor, to add astaxanthin in 15 parts of ratios;
(7) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging;
(8) allocate: allocate with anhydrous edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(9) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(10) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining astaxanthin compound assembled alcoholic drinks.
embodiment 2:
There is an astaxanthin compound assembled alcoholic drinks for effect of lowering blood sugar, prepared by following steps:
(1) herbal medicine pre-treatment: adopt pollution-free, pure herbal raw material, dries with pure water cleaning;
(2) pulverize: by matrimony vine, Rhizoma dioscoreae tissue mashing crusher machine; All the other herbal medicine cross 200 mesh sieves after pulverizing;
(3) coordinate: in matrimony vine 20 parts, Rhizoma dioscoreae 15 parts, 20 parts, shizandra berry, Tuber Fleeceflower Root 10 parts, Semen Coicis 15 parts, Ligusticum wallichii 8 parts, Herba Cistanches 5 parts, the root of kudzu vine 5 parts, skunk bush 6 parts, the root bark of tree peony 3 parts, 5 parts, Radix Glycyrrhizae, sweet Stevia 5 parts of ratios, herbal medicine is coordinated;
(4) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 10 times, hot digestion 30 ~ 60min;
(5) filter: filter, obtain Chinese herbal medicine leaching liquor;
(6) composite: in Chinese herbal medicine leaching liquor, to add astaxanthin in 10 parts of ratios;
(7) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging;
(8) allocate: allocate with anhydrous edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(9) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(10) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining astaxanthin compound assembled alcoholic drinks.
embodiment 3:
There is an astaxanthin compound assembled alcoholic drinks for effect of lowering blood sugar, prepared by following steps:
(1) herbal medicine pre-treatment: adopt pollution-free, pure herbal raw material, dries with pure water cleaning;
(2) pulverize: by matrimony vine, Rhizoma dioscoreae tissue mashing crusher machine; All the other herbal medicine cross 200 mesh sieves after pulverizing;
(3) coordinate: in matrimony vine 15 parts, Rhizoma dioscoreae 10 parts, 10 parts, shizandra berry, Tuber Fleeceflower Root 5 parts, Semen Coicis 10 parts, Ligusticum wallichii 5 parts, Herba Cistanches 3 parts, the root of kudzu vine 3 parts, skunk bush 4 parts, the root bark of tree peony 2 parts, 3 parts, Radix Glycyrrhizae, sweet Stevia 3 parts of ratios, herbal medicine is coordinated;
(4) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 10 times, hot digestion 30 ~ 60min;
(5) filter: filter, obtain Chinese herbal medicine leaching liquor;
(6) composite: in Chinese herbal medicine leaching liquor, to add astaxanthin in 20 parts of ratios;
(7) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging;
(8) allocate: allocate with anhydrous edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(9) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(10) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining astaxanthin compound assembled alcoholic drinks.
Above embodiment only for illustration of technical scheme of the present invention, but not is limited; Although be described in detail by invention with reference to previous embodiment, for the person of ordinary skill of the art, still the technical scheme described in previous embodiment can be modified, or equivalent replacement has been carried out to wherein portion of techniques feature; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.
Claims (1)
1. there is an astaxanthin compound assembled alcoholic drinks for effect of lowering blood sugar, it is characterized in that being prepared by following steps:
(1) herbal medicine pre-treatment: adopt pollution-free, pure herbal raw material, dries with pure water cleaning;
(2) pulverize: by matrimony vine, Rhizoma dioscoreae tissue mashing crusher machine; All the other herbal medicine cross 200 mesh sieves after pulverizing;
(3) coordinate: in matrimony vine 15 ~ 20 parts, Rhizoma dioscoreae 10 ~ 15 parts, 10 ~ 20 parts, shizandra berry, Tuber Fleeceflower Root 5 ~ 10 parts, Semen Coicis 10 ~ 15 parts, Ligusticum wallichii 5 ~ 8 parts, Herba Cistanches 3 ~ 5 parts, the root of kudzu vine 3 ~ 5 parts, skunk bush 4 ~ 6 parts, the root bark of tree peony 2 ~ 3 parts, 3 ~ 5 parts, Radix Glycyrrhizae, sweet Stevia 3 ~ 5 parts of ratios, herbal medicine is coordinated;
(4) herbal medicine lixiviate: the pure water adding herbal medicine mass ratio 10 times, hot digestion 30 ~ 60min;
(5) filter: filter, obtain Chinese herbal medicine leaching liquor;
(6) composite: in Chinese herbal medicine leaching liquor, to add astaxanthin in 10 ~ 20 parts of ratios;
(7) centrifugal: the centrifugal 15 ~ 20min of 3000r/min, disgorging;
(8) allocate: allocate with anhydrous edible ethanol, adjustment alcoholic strength≤24%, with citric acid adjustment pH to 4.0 ~ 4.5;
(9) centrifugal: the centrifugal 15 ~ 20min of 4500r/min, disgorging;
(10) filling, sterilization: adopt automatic filling machine filling and seal, by its sterilizing 30min under 0.2Mpa, 121 DEG C of conditions, obtaining astaxanthin compound assembled alcoholic drinks.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105560838A (en) * | 2016-01-29 | 2016-05-11 | 杭州鑫伟低碳技术研发有限公司 | Haematococcus pluvialis astaxanthin for adjuvant treatment of diabetes and preparation method thereof |
CN106190722A (en) * | 2016-07-11 | 2016-12-07 | 江苏恒顺醋业股份有限公司 | A kind of astaxanthin yellow wine and preparation method thereof |
US11696593B2 (en) | 2018-08-24 | 2023-07-11 | Bioscience Formulators, LLC | Astaxanthin nutritional compositions and uses |
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CN1270830A (en) * | 1999-04-19 | 2000-10-25 | 郭立文 | Sanjiangcha tea for reducing blood sugar, blood pressure and blood lipoid and its preparation |
CN102038260A (en) * | 2010-11-09 | 2011-05-04 | 万光瑞 | Chinese medicinal alcoholism relieving health-care beverage and preparation method thereof |
CN103191089A (en) * | 2013-03-29 | 2013-07-10 | 李树森 | Novel astaxanthin heath-care wine and preparation method thereof |
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Patent Citations (3)
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CN1270830A (en) * | 1999-04-19 | 2000-10-25 | 郭立文 | Sanjiangcha tea for reducing blood sugar, blood pressure and blood lipoid and its preparation |
CN102038260A (en) * | 2010-11-09 | 2011-05-04 | 万光瑞 | Chinese medicinal alcoholism relieving health-care beverage and preparation method thereof |
CN103191089A (en) * | 2013-03-29 | 2013-07-10 | 李树森 | Novel astaxanthin heath-care wine and preparation method thereof |
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CN105560838A (en) * | 2016-01-29 | 2016-05-11 | 杭州鑫伟低碳技术研发有限公司 | Haematococcus pluvialis astaxanthin for adjuvant treatment of diabetes and preparation method thereof |
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US11696593B2 (en) | 2018-08-24 | 2023-07-11 | Bioscience Formulators, LLC | Astaxanthin nutritional compositions and uses |
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