CN105595325A - Globefish fish skin health care capsule with stomach strengthening effect - Google Patents
Globefish fish skin health care capsule with stomach strengthening effect Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a globefish fish skin health care capsule with stomach strengthening effect, the globefish fish skin health care capsule is prepared by scientific compatibility of raw materials of globefish fish skin, yam, coix seed, hawthorn, rhizoma ligustici wallichii and dangshen by the process of formulation, mixing, homogenization, ultrasonic-assisted enzymatic hydrolysis, filtration, concentration, drying, sterilization and filling, preferably the raw materials comprise 30 to 50 parts of globefish fish skin, 10 to 15 parts of yam, 8 to 10 parts of coix seed, 10 to 15 parts of hawthorn, 3 to 5 parts of rhizoma ligustici wallichii and 2 to 3 parts of dangshen. The product has the advantages that through synergies between the globefish fish skin and the Chinese herbal medicines, immune function activity can be effectively enhanced, human gastrointestinal function can be comprehensively regulated, the stomach vitality is improved, body in vivo environment is governed, waste is discharged from the body, free radicals are eliminated, and the globefish fish skin health care capsule is safe, free of side effects and convenient to take, and has good market use prospects.
Description
Technical field
The present invention relates to a kind of globefish skin health-caring capsule with stomach invigorating effect, particularly a kind of health-caring capsule of making as raw material taking globefish skin and vegetable Chinese herbal medicine, belongs to field of health care food.
Background technology
Globe fish (Fugurubripes) in contain extremely toxic substance tetrodotoxin, this toxin has high economic worth and medical value. People go deep into %, careful to the research of tetrodotoxin, have but ignored the value of globe fish other side. Along with the development of non-toxic globefish cultivation and processing detoxification technology, the output of China's non-toxic globefish rises year by year, and year outlet rate more than 90%, has now become the main source that external globe fish is supplied with. The export processing of globe fish has produced the leftover bits and pieces such as a large amount of fish-skins, has caused significant wastage and the environmental pollution of resource. In globefish skin, contain a large amount of collagens, approximately 88.5%, to extract the quality raw materials of preparing gelatin, collagen peptide, collagen peptide has many important physiological functions, as suppress ACE, promote skin collagen metabolism, anti-oxidant, increase bone density etc., can be widely used in the fields such as medicine, cosmetics, health products. According to research reports, globefish skin has significant stomach invigorating effect.
Quickening, irregular, the quick food of living of rhythm of life, drinking beyond one's capacity etc. makes the increasing crowd of China occur the inferior health illnesss such as increasing disorder of function of stomach, gasteremphraxis, hydrochloric acid in gastric juice, stomachache jeopardizing the healthy of people, affects quality of life. Along with the continuous enhancing of people's prevention and health care consciousness, society increases day by day to the demand with immunological regulation efficiency health-care food. Chinese herbal medicine resource is the rarity of Chinese traditional culture, because of its effect significantly, green, safely, have no side effect, the application in field of health care food is further extensive. Result of study shows, utilize the health products of Chinese herbal medicine development to contain abundant nutritional labeling, be rich in trace element, the vitamin isoreactivity nutritional labelings such as polysaccharide, flavones, amino acid, potassium calcium, there is adjusting function of human body, improve stomach function, strengthen immunity, nourishing and fit keeping function, the effect such as promote longevity.
At present, also there is more drawback in the application in field of health care food of globefish skin and Chinese herbal medicine, is difficult to really bring into play the health-care efficacy of globefish skin and Chinese herbal medicine. The present invention is directed to the problems referred to above, develop a kind of health-caring capsule with stomach invigorating effect that utilizes globefish skin and composite Chinese herbal, meet the demand of market to stomach invigorating health food.
Summary of the invention
For overcoming the deficiencies in the prior art, the object of the present invention is to provide a kind of globefish skin health-caring capsule with stomach invigorating effect, this health-caring capsule has beneficial spleen stomach invigorating, strengthens stomach function, improves the effects such as body immunity.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The invention provides a kind of globefish skin health-caring capsule with stomach invigorating effect, it is characterized in that health-caring capsule raw material composition and quality proportioning are: 30～50 parts of globefish skins, 10～15 parts of Chinese yams, 8～10 parts of coix seeds, 10～15 parts of hawthorn, 3～5 parts of Ligusticum wallichiis, 2～3 parts of Radix Codonopsis.
The preferred technical solution of the present invention is: a kind of globefish skin health-caring capsule with stomach invigorating effect, is characterized in that: it is characterized in that health-caring capsule raw material composition and quality proportioning are: 40 parts of globefish skins, 12 parts of Chinese yams, 9 parts of coix seeds, 12 parts of hawthorn, 4 parts of Ligusticum wallichiis, 2.5 parts of Radix Codonopsis.
The invention provides a kind of globefish skin health-caring capsule with stomach invigorating effect, it is characterized in that preparing by following steps:
(1) pretreatment of raw material: by Chinese herbal medicine sorting used, remove impurity, go mouldy and have the raw material of disease and pest etc.;
(2) pulverize: respectively the raw materials such as coix seed, hawthorn, Ligusticum wallichii, Radix Codonopsis superminiature pulverizer is pulverized, crossed 100 mesh sieves;
(3) weigh allotment: each raw material is allocated according to aforementioned proportion;
(4) homogenate: add 20 times of pure water in mixed material, be stirred to globefish skin with homogenizer completely gluey;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 3～5% amylase, 1～2% cellulase, 1～2% pectase, under ultrasonic wave booster action condition, 40～60 DEG C of enzymolysis 3～5h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) drying and crushing: crushed after being dried, cross 200 mesh sieves;
(9) sterilizing: with cobalt-60 sterilizing;
(10) filling capsule: filling at indoor No. 0 capsule of cleaning;
(11) shaped article: by the capsule bottling after filling, labeling, coding obtains the globefish skin health-caring capsule with stomach invigorating effect.
The invention provides a kind of globefish skin health-caring capsule with stomach invigorating effect, carry out toxicology test and the safety evaluatio of health-caring capsule by animal experiment. Chmice acute Oral toxicity result of the test shows, this health-caring capsule is greater than high dose group 75mg/kgbw to chmice acute per os maximum tolerated dose; Genetic toxicity test mouse marrow cell micro nuclear test and two result of the tests of mouse sperm deformity test are all negative, show that this health-caring capsule is without mutagenesis; From rat 30d feeding trial, the behavior of rat sign is normal, figure is healthy, blood and blood parameters be also without ANOMALOUS VARIATIONS, and therefore the dosage of 75mg/kgbw (human body recommended amounts 150 times) belongs to safe dose; Genetic toxicity test and rat 30d feeding trial result are all negative, therefore determine that this health-caring capsule belongs to non-toxic type food, and people can be relieved edible safely.
The invention provides a kind of globefish skin health-caring capsule with stomach invigorating effect, it is advantageous that science compatibility globefish skin and multiple Chinese herbal medicine, can effectively strengthen immunologic function activity by the synergy between globefish skin and Chinese herbal medicine, regulate the each organ function of human body, particularly stomach invigorating effect, administers vivo environment comprehensively, discharge rubbish in body, eliminate free radical, safety has no side effect, instant. different Chinese herbal medicine nature and flavor are different, effect exists huge difference, after different Chinese herbal medicine combinations, there is complicated interaction relationship, and the proportioning between Chinese herbal medicine is closer, different proportionings also will make monarch relation that substantial variation occurs, thus make composite Chinese herbal be related to generation material alterations. the application is by globefish skin and Chinese yam, coix seed, hawthorn, Ligusticum wallichii, there is to each other complicated interaction relationship in the Chinese herbal medicines such as Radix Codonopsis, rational proportion, by the enzymolysis of the complex enzyme formulation under ultrasonic wave subsidiary conditions, active component in globefish skin and Chinese herbal medicine is fully utilized, obtain unforeseeable technique effect, what make health-caring capsule is related to generation material alterations, the TAC of the application's health-caring capsule reaches 592.01 ± 52.76U/mL, there is good immunoregulatory activity, mouse experiment result shows that health-caring capsule has significant stomach invigorating effect, in addition, result of the test shows to change health-caring capsule raw material composition or proportioning and can reduce the oxidation resistance (P < 0.01) of health-caring capsule, illustrates that the synergy between globefish skin and Chinese herbal medicine has played the effect of remarkable lifting health-caring capsule functional activity.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
There is the globefish skin health-caring capsule of stomach invigorating effect, prepare by following steps:
(1) pretreatment of raw material: by Chinese herbal medicine sorting used, remove impurity, go mouldy and have the raw material of disease and pest etc.;
(2) pulverize: respectively the raw materials such as coix seed, hawthorn, Ligusticum wallichii, Radix Codonopsis superminiature pulverizer is pulverized, crossed 100 mesh sieves;
(3) weigh allotment: each raw material is allocated according to 40 parts of globefish skins, 12 parts of Chinese yams, 9 parts of coix seeds, 12 parts of hawthorn, 4 parts of Ligusticum wallichiis, 2.5 parts of ratios of Radix Codonopsis;
(4) homogenate: add 20 times of pure water in mixed material, be stirred to globefish skin with homogenizer completely gluey;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 4% amylase, 1.5% cellulase, 1.5% pectase, under ultrasonic wave booster action condition, 40～60 DEG C of enzymolysis 4h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) drying and crushing: crushed after being dried, cross 200 mesh sieves;
(9) sterilizing: with cobalt-60 sterilizing;
(10) filling capsule: filling at indoor No. 0 capsule of cleaning;
(11) shaped article: by the capsule bottling after filling, labeling, coding obtains the globefish skin health-caring capsule with stomach invigorating effect.
Embodiment 2:
There is the globefish skin health-caring capsule of stomach invigorating effect, prepare by following steps:
(1) pretreatment of raw material: by Chinese herbal medicine sorting used, remove impurity, go mouldy and have the raw material of disease and pest etc.;
(2) pulverize: respectively the raw materials such as coix seed, hawthorn, Ligusticum wallichii, Radix Codonopsis superminiature pulverizer is pulverized, crossed 100 mesh sieves;
(3) weigh allotment: each raw material is allocated according to 50 parts of globefish skins, 10 parts of Chinese yams, 10 parts of coix seeds, 10 parts of hawthorn, 5 parts of Ligusticum wallichiis, 2 parts of ratios of Radix Codonopsis;
(4) homogenate: add 20 times of pure water in mixed material, be stirred to globefish skin with homogenizer completely gluey;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 5% amylase, 2% cellulase, 2% pectase, under ultrasonic wave booster action condition, 40～60 DEG C of enzymolysis 3h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) drying and crushing: crushed after being dried, cross 200 mesh sieves;
(9) sterilizing: with cobalt-60 sterilizing;
(10) filling capsule: filling at indoor No. 0 capsule of cleaning;
(11) shaped article: by the capsule bottling after filling, labeling, coding obtains the globefish skin health-caring capsule with stomach invigorating effect.
Embodiment 3:
There is the globefish skin health-caring capsule of stomach invigorating effect, prepare by following steps:
(1) pretreatment of raw material: by Chinese herbal medicine sorting used, remove impurity, go mouldy and have the raw material of disease and pest etc.;
(2) pulverize: respectively the raw materials such as coix seed, hawthorn, Ligusticum wallichii, Radix Codonopsis superminiature pulverizer is pulverized, crossed 100 mesh sieves;
(3) weigh allotment: each raw material is allocated according to 30 parts of globefish skins, 15 parts of Chinese yams, 8 parts of coix seeds, 15 parts of hawthorn, 3 parts of Ligusticum wallichiis, 3 parts of ratios of Radix Codonopsis;
(4) homogenate: add 20 times of pure water in mixed material, be stirred to globefish skin with homogenizer completely gluey;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 3% amylase, 1% cellulase, 1% pectase, under ultrasonic wave booster action condition, 40～60 DEG C of enzymolysis 5h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) drying and crushing: crushed after being dried, cross 200 mesh sieves;
(9) sterilizing: with cobalt-60 sterilizing;
(10) filling capsule: filling at indoor No. 0 capsule of cleaning;
(11) shaped article: by the capsule bottling after filling, labeling, coding obtains the globefish skin health-caring capsule with stomach invigorating effect.
Above embodiment is only for technical scheme of the present invention is described, but not is limited; Although with reference to previous embodiment to being had been described in detail by invention, for the person of ordinary skill of the art, the technical scheme that still can record previous embodiment is modified, or part technical characterictic is wherein equal to replacement; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.
Claims (1)
1. a globefish skin health-caring capsule with stomach invigorating effect, is characterized in that preparing by following steps:
(1) pretreatment of raw material: by Chinese herbal medicine sorting used, remove impurity, go mouldy and have the raw material of disease and pest etc.;
(2) pulverize: respectively the raw materials such as coix seed, hawthorn, Ligusticum wallichii, Radix Codonopsis superminiature pulverizer is pulverized, crossed 100 mesh sieves;
(3) weigh allotment: each raw material is allocated according to 30～50 parts of globefish skins, 10～15 parts of Chinese yams, 8～10 parts of coix seeds, 10～15 parts of hawthorn, 3～5 parts of Ligusticum wallichiis, 2～3 parts of ratios of Radix Codonopsis;
(4) homogenate: add 20 times of pure water in mixed material, be stirred to globefish skin with homogenizer completely gluey;
(5) ultrasound-assisted enzymolysis: add feed liquid mass ratio 3～5% amylase, 1～2% cellulase, 1～2% pectase, under ultrasonic wave booster action condition, 40～60 DEG C of enzymolysis 3～5h,
(6) filter: Separation of Solid and Liquid, remove Chinese herbal medicine residue;
(7) concentrated: the feed liquid after filtration is concentrated into pasty state;
(8) drying and crushing: crushed after being dried, cross 200 mesh sieves;
(9) sterilizing: with cobalt-60 sterilizing;
(10) filling capsule: filling at indoor No. 0 capsule of cleaning;
(11) shaped article: by the capsule bottling after filling, labeling, coding obtains the globefish skin health-caring capsule with stomach invigorating effect.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510951377.XA CN105595325A (en) | 2015-12-19 | 2015-12-19 | Globefish fish skin health care capsule with stomach strengthening effect |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510951377.XA CN105595325A (en) | 2015-12-19 | 2015-12-19 | Globefish fish skin health care capsule with stomach strengthening effect |
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| CN105595325A true CN105595325A (en) | 2016-05-25 |
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| CN201510951377.XA Pending CN105595325A (en) | 2015-12-19 | 2015-12-19 | Globefish fish skin health care capsule with stomach strengthening effect |
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|---|---|---|---|---|
| CN1745829A (en) * | 2005-09-29 | 2006-03-15 | 李广中 | Zijing stomach tonifying pill |
| CN101167882A (en) * | 2007-11-08 | 2008-04-30 | 西安永航生物医药科技股份有限公司 | Capsule for anti-oxidation |
| CN101182357A (en) * | 2007-11-23 | 2008-05-21 | 大连工业大学 | Globefish skin active collagen and method for preparing peptide thereof |
| CN104489666A (en) * | 2014-12-10 | 2015-04-08 | 常州诺瑞格纳米科技有限公司 | Stomach-nourishing health product |
| US20150274791A1 (en) * | 2012-10-29 | 2015-10-01 | Matis Ohf. | Use of natural antioxidants during enzymatic hydrolysis of aquatic protein to obtain high quality aquatic protein hydrolysates |
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