CN104887740A - Astaxanthin healthcare capsule with immunity regulating efficacy - Google Patents

Astaxanthin healthcare capsule with immunity regulating efficacy Download PDF

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Publication number
CN104887740A
CN104887740A CN201510345554.XA CN201510345554A CN104887740A CN 104887740 A CN104887740 A CN 104887740A CN 201510345554 A CN201510345554 A CN 201510345554A CN 104887740 A CN104887740 A CN 104887740A
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China
Prior art keywords
astaxanthin
parts
capsule
raw material
health
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Pending
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CN201510345554.XA
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Chinese (zh)
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徐伦超
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Great Marine Health Food Co Ltd In Qingdao
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Great Marine Health Food Co Ltd In Qingdao
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Priority to CN201510345554.XA priority Critical patent/CN104887740A/en
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Abstract

The invention discloses astaxanthin healthcare capsules with immunity regulating efficacy. The astaxanthin healthcare capsules are prepared from astaxanthin, astragalus membranaceus, grifola, capillary artemisia, Chinese angelica, stevia rebaudiana and the like according to scientific compatibility and are preferably prepared from 20-30 parts of the astaxanthin, 10-15 parts the astragalus membranaceus, 8-10 parts of the grifola, 10-15 parts of the capillary artemisia, 3-5 parts of Chinese angelica and 2-3 parts of the stevia rebaudiana according to a preparation technology which includes the steps of blending, mixing, sterilizing and capsule filling. By the aid of synergistic effects of the astaxanthin and Chinese herbal medicines, the astaxanthin healthcare capsules have the advantages that functional activity of immunity can be boosted effectively, functions of various organs of a human body can be regulated comprehensively, an environment inside the human body can be governed, waste inside the human body can be discharged, free radicals can be eliminated, and safety, no side effect, convenience in taking and good market application prospect are achieved.

Description

A kind of astaxanthin health-caring capsule with immunomodulating effect
Technical field
The present invention relates to a kind of astaxanthin health-caring capsule with immunomodulating effect, particularly a kind of health-caring capsule made for raw material with astaxanthin and vegetable Chinese herbal medicine, belong to field of health care food.
Technical background
Astaxanthin (astaxanthin), also known as " ASX ", is a kind of Red carotenoids found from shrimp Eriocheir sinensis shell, Concha Ostreae, salmon and algae, fungus.There are some researches show in recent years, natural astaxanthin has stronger antioxidant activity, has scavenging free radicals, protection blood vessel, reduction cholesterol, skin protection, vision protection, neuroprotective system, prevention senile dementia, alleviates many-sided nutrition health-care functions such as arthralgia; Particularly natural astaxanthin has strong antioxidant activity, is called as " supper vitamin E ", " super antioxidant ".A large amount of human trial of natural astaxanthin and animal experiment verified it be a kind of very safe carotenoid.In Japan, natural astaxanthin also for food and animal feed, U.S. FDA, European Union, Canadian food surveillance office also approved it as the feed additive of salmon class.Because it has multiple biological effect, the application in nutrition and medicine has vast potential for future development, and particularly astaxanthin has boundless application prospect as the high-class healthy food of the mankind.
The subhealth state diseases such as the quickening of rhythm of life and irregularities, quick food, insobriety etc. make the increasing crowd of China occur increasing hyperlipidemia, hyperglycemia, hypertension, obesity, suffer from a deficiency of the kidney, lethargy, jeopardize the healthy of people, affect quality of life.Along with the continuous enhancing of people's prevention and health care consciousness, society increases day by day to the demand with immunomodulating efficiency health-care food.Chinese herbal medicine resource is the rarity of Chinese traditional culture, because of its effect significantly, green, safely, have no side effect, the application in field of health care food is further extensive.Result of study shows, the health product utilizing Chinese herbal medicine to develop contain abundant nutritional labeling, be rich in trace element, the vitamin isoreactivity nutritional labelings such as polysaccharide, flavone, aminoacid, potassium calcium, there is adjustment function of human body, the effects such as enhancing immunity, nourishing and fit keeping function, life lengthening.
At present, also there is more drawback in the application of Chinese herbal medicine in field of health care food, is difficult to the health-care effect really playing Chinese herbal medicine.The present invention is directed to the problems referred to above, develop a kind of health-caring capsule with immunomodulating effect utilizing astaxanthin and composite Chinese herbal, meet the demand of market to the health food of efficient immunoloregulation function.
Summary of the invention
For overcoming the deficiencies in the prior art, the object of the present invention is to provide a kind of astaxanthin health-caring capsule with immunomodulating effect, this health-caring capsule can strengthen human immunity effect.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The invention provides a kind of astaxanthin health-caring capsule with immunomodulating effect, it is characterized in that health-caring capsule raw material composition and quality proportioning are: astaxanthin 20 ~ 30 parts, the Radix Astragali 10 ~ 15 parts, Polyporus 8 ~ 10 parts, Artemisia anethoicles Mattf 10 ~ 15 parts, Radix Angelicae Sinensis 3 ~ 5 parts, Folium Stevlae Rebaudianae 2 ~ 3 parts.
The preferred technical solution of the present invention is: a kind of astaxanthin health-caring capsule with immunomodulating effect, is characterized in that: it is characterized in that health-caring capsule raw material composition and quality proportioning are: astaxanthin 25 parts, the Radix Astragali 12 parts, Polyporus 9 parts, Artemisia anethoicles Mattf 12 parts, Radix Angelicae Sinensis 4 parts, Folium Stevlae Rebaudianae 2.5 parts.
The invention provides a kind of astaxanthin health-caring capsule with immunomodulating effect, it is characterized in that being prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) dry: raw material is dried to constant weight respectively in microwave vacuum dryer;
(3) pulverize: respectively the raw materials such as astaxanthin, the Radix Astragali, Polyporus, Artemisia anethoicles Mattf, Radix Angelicae Sinensis, Folium Stevlae Rebaudianae superminiature pulverizer is pulverized, cross 2000 mesh sieves;
(4) allotment is weighed: allocated according to aforementioned proportion by the raw material after pulverizing;
(5) mix: by the deployed abundant mix homogeneously of raw material mixed at high speed blender;
(6) sterilizing: with cobalt-60 sterilizing;
(7) fill capsule: in the indoor No. 0 capsule fill of cleaning;
(8) shaped article: by the capsule bottling after fill, labeling, namely coding obtains the astaxanthin health-caring capsule with immunomodulating effect.
The invention provides a kind of astaxanthin health-caring capsule with immunomodulating effect, carried out toxicology test and the safety evaluatio of health-caring capsule by animal experiment.Chmice acute Oral toxicity result of the test shows, this health-caring capsule is greater than high dose group 75mg/kgbw to chmice acute per os maximum tolerated dose; Genetic toxicity test mouse marrow cell micro nuclear test and mouse inbred strain two result of the tests are feminine gender, show that this health-caring capsule is without mutagenic action; From rat 30d feeding trial, the behavior of rat sign is normal, figure is healthy, blood and blood parameters also change without exception, and therefore the dosage (150 times of human body recommended amounts) of 75mg/kgbw belongs to safe dose; Genetic toxicity test and rat 30d feeding trial result are feminine gender, therefore determine that this health-caring capsule belongs to non-toxic type food, and people can be safe relieved edible.
The invention provides a kind of astaxanthin health-caring capsule with immunomodulating effect, it is advantageous that scientific compatibility astaxanthin and multiple Chinese herbal medicine, immunologic function activity can be effectively strengthened by the synergism between astaxanthin and Chinese herbal medicine, the each organ function of comprehensive adjustment human body, administer internal milieu, discharge rubbish in body, eliminate free radical, safety has no side effect, instant.Different Chinese herbal medicine nature and flavor are different, effect also exists huge difference, complicated interaction relationship is there is after different Chinese herbal medicine combinations, and proportioning between Chinese herbal medicine is closer, different ratio also will make monarch relation that substantial change occurs, thus make the relation generation material alterations of composite Chinese herbal.Complicated interaction relationship is there is to each other in the application by Chinese herbal medicine such as astaxanthin and the Radix Astragali, Polyporus, Artemisia anethoicles Mattf, Radix Angelicae Sinensis, Folium Stevlae Rebaudianae, rational proportion, achieve unforeseeable technique effect, make the relation generation material alterations of health-caring capsule, the total antioxidant capacity of the application's health-caring capsule reaches 775.36 ± 62.31U/mL, has good immunoregulatory activity; And result of the test shows that change health-caring capsule raw material composition or proportioning can reduce the oxidation resistance (P<0.01) of health-caring capsule, illustrates that the synergism between astaxanthin and Chinese herbal medicine serves the effect significantly promoting health-caring capsule functional activity.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
There is the astaxanthin health-caring capsule of immunomodulating effect, prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) dry: raw material is dried to constant weight respectively in microwave vacuum dryer;
(3) pulverize: respectively the raw materials such as astaxanthin, the Radix Astragali, Polyporus, Artemisia anethoicles Mattf, Radix Angelicae Sinensis, Folium Stevlae Rebaudianae superminiature pulverizer is pulverized, cross 2000 mesh sieves;
(4) allotment is weighed: allocated according to astaxanthin 25 parts, the Radix Astragali 12 parts, Polyporus 9 parts, Artemisia anethoicles Mattf 12 parts, Radix Angelicae Sinensis 4 parts, Folium Stevlae Rebaudianae 2.5 parts of ratios by the raw material after pulverizing;
(5) mix: by the deployed abundant mix homogeneously of raw material mixed at high speed blender;
(6) sterilizing: with cobalt-60 sterilizing;
(7) fill capsule: in the indoor No. 0 capsule fill of cleaning;
(8) shaped article: by the capsule bottling after fill, labeling, namely coding obtains the astaxanthin health-caring capsule with immunomodulating effect.
Embodiment 2:
There is the astaxanthin health-caring capsule of immunomodulating effect, prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) dry: raw material is dried to constant weight respectively in microwave vacuum dryer;
(3) pulverize: respectively the raw materials such as astaxanthin, the Radix Astragali, Polyporus, Artemisia anethoicles Mattf, Radix Angelicae Sinensis, Folium Stevlae Rebaudianae superminiature pulverizer is pulverized, cross 2000 mesh sieves;
(4) allotment is weighed: allocated according to astaxanthin 30 parts, the Radix Astragali 10 parts, Polyporus 8 parts, Artemisia anethoicles Mattf 10 parts, Radix Angelicae Sinensis 3 parts, Folium Stevlae Rebaudianae 2 parts of ratios by the raw material after pulverizing;
(5) mix: by the deployed abundant mix homogeneously of raw material mixed at high speed blender;
(6) sterilizing: with cobalt-60 sterilizing;
(7) fill capsule: in the indoor No. 0 capsule fill of cleaning;
(8) shaped article: by the capsule bottling after fill, labeling, namely coding obtains the astaxanthin health-caring capsule with immunomodulating effect.
Embodiment 3:
There is the astaxanthin health-caring capsule of immunomodulating effect, prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) dry: raw material is dried to constant weight respectively in microwave vacuum dryer;
(3) pulverize: respectively the raw materials such as astaxanthin, the Radix Astragali, Polyporus, Artemisia anethoicles Mattf, Radix Angelicae Sinensis, Folium Stevlae Rebaudianae superminiature pulverizer is pulverized, cross 2000 mesh sieves;
(4) allotment is weighed: allocated according to astaxanthin 20 parts, the Radix Astragali 15 parts, Polyporus 10 parts, Artemisia anethoicles Mattf 15 parts, Radix Angelicae Sinensis 5 parts, Folium Stevlae Rebaudianae 3 parts of ratios by the raw material after pulverizing;
(5) mix: by the deployed abundant mix homogeneously of raw material mixed at high speed blender;
(6) sterilizing: with cobalt-60 sterilizing;
(7) fill capsule: in the indoor No. 0 capsule fill of cleaning;
(8) shaped article: by the capsule bottling after fill, labeling, namely coding obtains the astaxanthin health-caring capsule with immunomodulating effect.
Above embodiment only for illustration of technical scheme of the present invention, but not is limited; Although be described in detail by invention with reference to previous embodiment, for the person of ordinary skill of the art, still the technical scheme described in previous embodiment can be modified, or equivalent replacement has been carried out to wherein portion of techniques feature; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.

Claims (1)

1. there is the astaxanthin health-caring capsule of immunomodulating effect, it is characterized in that being prepared by following steps:
(1) pretreatment of raw material: sorted by Chinese herbal medicine used, removes impurity, goes mouldy and has the raw material etc. of disease and pest;
(2) dry: raw material is dried to constant weight respectively in microwave vacuum dryer;
(3) pulverize: respectively the raw materials such as astaxanthin, the Radix Astragali, Polyporus, Artemisia anethoicles Mattf, Radix Angelicae Sinensis, Folium Stevlae Rebaudianae superminiature pulverizer is pulverized, cross 2000 mesh sieves;
(4) allotment is weighed: allocated according to astaxanthin 20 ~ 30 parts, the Radix Astragali 10 ~ 15 parts, Polyporus 8 ~ 10 parts, Artemisia anethoicles Mattf 10 ~ 15 parts, Radix Angelicae Sinensis 3 ~ 5 parts, Folium Stevlae Rebaudianae 2 ~ 3 parts of ratios by the raw material after pulverizing;
(5) mix: by the deployed abundant mix homogeneously of raw material mixed at high speed blender;
(6) sterilizing: with cobalt-60 sterilizing;
(7) fill capsule: in the indoor No. 0 capsule fill of cleaning;
(8) shaped article: by the capsule bottling after fill, labeling, namely coding obtains the astaxanthin health-caring capsule with immunomodulating effect.
CN201510345554.XA 2015-06-19 2015-06-19 Astaxanthin healthcare capsule with immunity regulating efficacy Pending CN104887740A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105394749A (en) * 2015-10-23 2016-03-16 武汉龙族药号生物医药科技有限公司 Formula, preparation method and application of astaxanthin-containing health food
CN106072546A (en) * 2016-06-28 2016-11-09 青岛浩大海洋保健食品有限公司 A kind of relieving alcoholism and protecting the liver health-caring capsule
CN108652002A (en) * 2018-03-13 2018-10-16 云南爱尔康生物技术有限公司 A kind of astaxanthin meal replacement powder and preparation method thereof
CN109078190A (en) * 2018-10-30 2018-12-25 单风平 A kind of composition and preparation method for cancer patient's immunity of organism balance adjustment

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1363338A (en) * 2001-01-09 2002-08-14 杨孟君 Nano medicine 'Donggui Buxue' and its preparing process

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1363338A (en) * 2001-01-09 2002-08-14 杨孟君 Nano medicine 'Donggui Buxue' and its preparing process

Non-Patent Citations (2)

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Title
祖炬雄: "论中药与机体免疫的研究概况", 《中医药信息》 *
裴凌鹏: "虾青素体内抗肿瘤及其免疫调节作用的实验研究", 《上海中医药杂志》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105394749A (en) * 2015-10-23 2016-03-16 武汉龙族药号生物医药科技有限公司 Formula, preparation method and application of astaxanthin-containing health food
CN105394749B (en) * 2015-10-23 2018-03-20 武汉龙族药号生物医药科技有限公司 A kind of Ricipe for health care food and preparation method and application containing astaxanthin
CN106072546A (en) * 2016-06-28 2016-11-09 青岛浩大海洋保健食品有限公司 A kind of relieving alcoholism and protecting the liver health-caring capsule
CN108652002A (en) * 2018-03-13 2018-10-16 云南爱尔康生物技术有限公司 A kind of astaxanthin meal replacement powder and preparation method thereof
CN109078190A (en) * 2018-10-30 2018-12-25 单风平 A kind of composition and preparation method for cancer patient's immunity of organism balance adjustment

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Application publication date: 20150909

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