CN105559060B - A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule - Google Patents

A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule Download PDF

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CN105559060B
CN105559060B CN201510951355.3A CN201510951355A CN105559060B CN 105559060 B CN105559060 B CN 105559060B CN 201510951355 A CN201510951355 A CN 201510951355A CN 105559060 B CN105559060 B CN 105559060B
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parts
fish oil
capsule
filefish
filefish fish
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CN105559060A (en
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徐伦超
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Qingdao Vast Marine Biological Polytron Technologies Inc
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is by raw material scientific compatibilities such as filefish oil, Chinese yam, the bighead atractylodes rhizome, hawthorn 1, radix scutellariae, red ginseng, radix glycyrrhizaes, it is preferred that obtaining 1 part of 3~5 parts of filefish fish oil, 10~15 parts of Chinese yam, 8~10 parts of the bighead atractylodes rhizome, 10~15 parts of hawthorn, 3~5 parts of radix scutellariae, 2~3 parts of red ginseng, radix glycyrrhizae formula, then prepared by allotment, mixing, ultrasound-assisted enzymolysis, filtering, concentration, compounding, drying, sterilizing, filling Capsule technologies.The product advantage is effectively strengthen immunologic function activity by the synergy between filefish fish oil and Chinese herbal medicine, regulation human gastrointestinal tract's function comprehensively, improve stomach vigor, administer vivo environment, internal rubbish are discharged, free radical is eliminated, has no side effect safely, instant, there is preferable market application foreground.

Description

A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule
Technical field
The present invention relates to a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, and particularly one kind is with filefish fish oil and plant medium-height grass Medicine is health-caring capsule made of raw material, belongs to field of health care food.
Background technology
Globe fish(Fugu rubripes) in contain extremely toxic substance tetrodotoxin, this toxin has high economy Value and medical value.%, careful is relatively goed deep into research of the people to tetrodotoxin, but have ignored the valency of globe fish other side Value.As non-toxic globefish cultivates and processes the development of detoxification technology, the yield of China's non-toxic globefish rises year by year, year outlet Rate more than 90%, as the main source of external globe fish supply.Identified through State Aquatic Product Quality Monitoring Test Centre: The protein content of filefish is up to 17.71%, and fat content is only 0.62%, and unsaturated fatty acid content is more than 20%, wherein DHA (The main component of docosapentaenoic acid)Account for 15.36%, EPA 6.19%.Filefish fish oil is primarily referred to as from leftover bits and pieces such as filefish liver, ovaries Extract after middle detoxification, there is tumor suppression, strengthen immunity, give up various addictive functions, be usually used in food, health care at present Product, medicine etc., there is preferable application and development value.
The quickening of rhythm of life, irregular, the quick food of life, drink beyond one's capacity etc. so that the increasing crowd in China goes out The now inferior health illness such as increasing disorder of function of stomach, gasteremphraxis, hydrochloric acid in gastric juice, stomachache, jeopardize the health of people, influence to live Quality.With people's prevention and health care realize continuous enhancing, society to the demand with immunological regulation efficiency health-care food increasingly Increase.Chinese herbal medicine resource is the rarity of Chinese traditional culture, because its effect significantly, green, safely, have no side effect, health care eat Application in product field is further extensive.Result of study shows, abundant nutritional ingredient is contained using the health products of Chinese herbal medicine development, Rich in the trace elements such as polysaccharide, flavones, amino acid, potassium calcium, vitamin isoreactivity nutritional ingredient, there is regulation function of human body, change Kind stomach function, strengthen immunity, nourishing and fit keeping function, promote longevity and other effects.
At present, also there is the drawbacks of more in the application of filefish fish oil and Chinese herbal medicine in field of health care food, it is difficult to really Play the health-care efficacy of filefish fish oil and Chinese herbal medicine.The present invention is in view of the above-mentioned problems, exploitation is a kind of using filefish fish oil and compound The health-caring capsule with stomach invigorating effect of Chinese herbal medicine, meets the needs of market is to stomach-invigoratinghealth health care food.
The content of the invention
For overcome the deficiencies in the prior art, it is an object of the invention to provide a kind of beneficial spleen stomach invigorating filefish fish oil health care glue Capsule, the health-caring capsule have beneficial spleen stomach invigorating, enhancing stomach function, improve body immunity and other effects.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The present invention provides a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is characterised in that health-caring capsule raw material forms and matter Measuring proportioning is:3~5 parts of filefish fish oil, 10~15 parts of Chinese yam, 8~10 parts of the bighead atractylodes rhizome, 10~15 parts of hawthorn, 3~5 parts of radix scutellariae, red ginseng 2~3 parts, 1 part of radix glycyrrhizae.
The preferred technical solution of the present invention is:A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is characterised in that:Its feature It is that health-caring capsule raw material composition and quality proportioning are:4 parts of filefish fish oil, 12 parts of Chinese yam, 9 parts of the bighead atractylodes rhizome, 12 parts of hawthorn, radix scutellariae 4 Part, 2.5 parts of red ginseng, 1 part of radix glycyrrhizae.
The present invention provides a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is characterised in that is prepared by following steps:
(1)Pretreatment of raw material:Chinese herbal medicine used is sorted, raw material for go the removal of impurity, going mouldy and have pest and disease damage etc.;
(2)Crush:The bighead atractylodes rhizome, radix scutellariae, red ginseng, radix glycyrrhizae are crushed with superminiature pulverizer respectively, cross 100 mesh sieves;Chinese yam, mountain Short, bristly hair or beard is homogenized with refiner;
(3)Weigh allotment:Each raw material is allocated according to aforementioned proportion;
(4)Homogenate:Raw material in addition to filefish fish oil is well mixed, 20 times of mass ratioes of material is pure after addition mixing Water;
(5)Ultrasound-assisted enzymolysis:Add the amylase of feed liquid mass ratio 3~5%, 1~2% cellulase, 1~2% pectin Enzyme, under ultrasonic assistant action condition, 40~60 DEG C of 3~5h of enzymolysis,
(6)Filtering:Separation of solid and liquid, remove Chinese herbal medicine residue;
(7)Concentration:Feed liquid after filtering is concentrated into pasty state;
(8)Compounding:Filefish fish oil is well mixed with the extract after concentration;
(9)Drying and crushing:Crushed after being dried, cross 200 mesh sieves;
(10)Sterilizing:Sterilized with cobalt -60;
(11)Filling capsule:It is filling in clean indoor No. 0 capsule;
(12)Shaped article:Capsule bottling after will be filling, labeling, coding produce the filefish fish oil with stomach invigorating effect and protected Strong capsule.
The present invention provides a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, and the toxicity of health-caring capsule is carried out by animal experiment Learn experiment and safety evaluatio.Chmice acute Oral toxicity result of the test shows that this health-caring capsule is to the oral maximum of chmice acute Tolerance dose is more than high dose group 75mg/kgbw;Genetic toxicity test mouse marrow cell micro nuclear test and mouse sperm are abnormal It is feminine gender that shape, which tests two result of the tests, shows the health-caring capsule without mutagenesis;From rat 30d feeding trials, Rat sign behavior is normal, figure is healthy, blood and blood parameters also change without exception, therefore 75mg/kgbw agent Amount(150 times of human body recommended amounts)Belong to safe dose;Genetic toxicity test and rat 30d feeding trial results are feminine gender, It is thus determined that this health-caring capsule belongs to nontoxic based food, people can be eaten with safe and secure.
The present invention provides a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is advantageous that scientific compatibility filefish fish oil and more Kind Chinese herbal medicine, immunologic function activity can effectively be strengthened by the synergy between filefish fish oil and Chinese herbal medicine, adjust people comprehensively Each organ function of body, particularly stomach invigorating effect, vivo environment is administered, discharge internal rubbish, eliminate free radical, safety is made without pair With instant.Different Chinese herbal medicine nature and flavor are different, and effect exists there is huge difference after the combination of different Chinese herbal medicines Complicated interaction relationship, and the proportioning between Chinese herbal medicine is closer, different ratio also will occur monarch relation Substantial change, so that material alterations occurs for the relation of composite Chinese herbal.The application passes through filefish fish oil and Chinese yam, white There is complicated interaction relationship in the Chinese herbal medicines such as art, hawthorn, radix scutellariae, red ginseng, rational proportion, pass through ultrasonic assistant to each other Under the conditions of complex enzyme formulation enzymolysis, the active component in filefish fish oil and Chinese herbal medicine is fully utilized, obtain Unexpected technique effect, make the relation of health-caring capsule that material alterations, the total antioxidation of the application health-caring capsule occur Ability reaches 585.22 ± 42.14U/mL, has preferable immunoregulatory activity, and mouse test results show that health-caring capsule has Significant stomach invigorating effect;In addition, result of the test shows that the anti-of health-caring capsule can be reduced by changing health-caring capsule raw material composition or proportioning Oxidability(P<0.01), illustrate that the synergy between filefish fish oil and Chinese herbal medicine serves and be obviously improved health-caring capsule function The effect of activity.
Embodiment
With reference to embodiment, the present invention will be further described.
Embodiment 1:
A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, is prepared by following steps:
(1)Pretreatment of raw material:Chinese herbal medicine used is sorted, raw material for go the removal of impurity, going mouldy and have pest and disease damage etc.;
(2)Crush:The bighead atractylodes rhizome, radix scutellariae, red ginseng, radix glycyrrhizae are crushed with superminiature pulverizer respectively, cross 100 mesh sieves;Chinese yam, mountain Short, bristly hair or beard is homogenized with refiner;
(3)Weigh allotment:By each raw material according to 4 parts of filefish fish oil, 12 parts of Chinese yam, 9 parts of the bighead atractylodes rhizome, 12 parts of hawthorn, radix scutellariae 4 1 part of part, 2.5 parts of red ginseng, radix glycyrrhizae ratio allotment;
(4)Homogenate:Raw material in addition to filefish fish oil is well mixed, 20 times of mass ratioes of material is pure after addition mixing Water;
(5)Ultrasound-assisted enzymolysis:The amylase of feed liquid mass ratio 4%, 1.5% cellulase, 1.5% pectase are added, super Under the conditions of sound wave booster action, 40~60 DEG C of enzymolysis 4h,
(6)Filtering:Separation of solid and liquid, remove Chinese herbal medicine residue;
(7)Concentration:Feed liquid after filtering is concentrated into pasty state;
(8)Compounding:Filefish fish oil is well mixed with the extract after concentration;
(9)Drying and crushing:Crushed after being dried, cross 200 mesh sieves;
(10)Sterilizing:Sterilized with cobalt -60;
(11)Filling capsule:It is filling in clean indoor No. 0 capsule;
(12)Shaped article:Capsule bottling after will be filling, labeling, coding produce the filefish fish oil with stomach invigorating effect and protected Strong capsule.
Embodiment 2:
A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, is prepared by following steps:
(1)Pretreatment of raw material:Chinese herbal medicine used is sorted, raw material for go the removal of impurity, going mouldy and have pest and disease damage etc.;
(2)Crush:The bighead atractylodes rhizome, radix scutellariae, red ginseng, radix glycyrrhizae are crushed with superminiature pulverizer respectively, cross 100 mesh sieves;Chinese yam, mountain Short, bristly hair or beard is homogenized with refiner;
(3)Weigh allotment:By each raw material according to 5 parts of filefish fish oil, 10 parts of Chinese yam, 10 parts of the bighead atractylodes rhizome, 10 parts of hawthorn, radix scutellariae 5 1 part of part, 2 parts of red ginseng, radix glycyrrhizae ratio allotment;
(4)Homogenate:Raw material in addition to filefish fish oil is well mixed, 20 times of mass ratioes of material is pure after addition mixing Water;
(5)Ultrasound-assisted enzymolysis:The amylase of feed liquid mass ratio 5%, 2% cellulase, 2% pectase are added, in ultrasonic wave Under the conditions of booster action, 40~60 DEG C of enzymolysis 3h,
(6)Filtering:Separation of solid and liquid, remove Chinese herbal medicine residue;
(7)Concentration:Feed liquid after filtering is concentrated into pasty state;
(8)Compounding:Filefish fish oil is well mixed with the extract after concentration;
(9)Drying and crushing:Crushed after being dried, cross 200 mesh sieves;
(10)Sterilizing:Sterilized with cobalt -60;
(11)Filling capsule:It is filling in clean indoor No. 0 capsule;
(12)Shaped article:Capsule bottling after will be filling, labeling, coding produce the filefish fish oil with stomach invigorating effect and protected Strong capsule.
Embodiment 3:
A kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, is prepared by following steps:
(1)Pretreatment of raw material:Chinese herbal medicine used is sorted, raw material for go the removal of impurity, going mouldy and have pest and disease damage etc.;
(2)Crush:The bighead atractylodes rhizome, radix scutellariae, red ginseng, radix glycyrrhizae are crushed with superminiature pulverizer respectively, cross 100 mesh sieves;Chinese yam, mountain Short, bristly hair or beard is homogenized with refiner;
(3)Weigh allotment:By each raw material according to 3 parts of filefish fish oil, 15 parts of Chinese yam, 8 parts of the bighead atractylodes rhizome, 15 parts of hawthorn, radix scutellariae 3 1 part of part, 3 parts of red ginseng, radix glycyrrhizae ratio allotment;
(4)Homogenate:Raw material in addition to filefish fish oil is well mixed, 20 times of mass ratioes of material is pure after addition mixing Water;
(5)Ultrasound-assisted enzymolysis:The amylase of feed liquid mass ratio 3%, 1% cellulase, 1% pectase are added, in ultrasonic wave Under the conditions of booster action, 40~60 DEG C of enzymolysis 5h,
(6)Filtering:Separation of solid and liquid, remove Chinese herbal medicine residue;
(7)Concentration:Feed liquid after filtering is concentrated into pasty state;
(8)Compounding:Filefish fish oil is well mixed with the extract after concentration;
(9)Drying and crushing:Crushed after being dried, cross 200 mesh sieves;
(10)Sterilizing:Sterilized with cobalt -60;
(11)Filling capsule:It is filling in clean indoor No. 0 capsule;
(12)Shaped article:Capsule bottling after will be filling, labeling, coding produce the filefish fish oil with stomach invigorating effect and protected Strong capsule.
Above example is merely to illustrate technical scheme, rather than is limited;Although with reference to foregoing reality Example is applied to being described in detail by invention, but for the person of ordinary skill of the art, still can be to foregoing reality Apply the technical scheme described in example to modify, or equivalent substitution is carried out to which part technical characteristic;And to these modifications Or replace, the essence of appropriate technical solution is departed from the spirit and scope of claimed technical solution of the invention.

Claims (1)

1. a kind of beneficial spleen stomach invigorating filefish fish oil health-caring capsule, it is characterised in that prepared by following steps:
(1)Pretreatment of raw material:Chinese herbal medicine used is sorted, the raw material for go the removal of impurity, going mouldy and have pest and disease damage;
(2)Crush:The bighead atractylodes rhizome, radix scutellariae, red ginseng, radix glycyrrhizae are crushed with superminiature pulverizer respectively, cross 100 mesh sieves;Chinese yam, hawthorn are used Refiner is homogenized;
(3)Weigh allotment:By each raw material according to 3~5 parts of filefish fish oil, 10~15 parts of Chinese yam, 8~10 parts of the bighead atractylodes rhizome, hawthorn 10~ 15 parts, 3~5 parts of radix scutellariae, 2~3 parts of red ginseng, the allotment of 1 part of ratio of radix glycyrrhizae;
(4)Homogenate:Raw material in addition to filefish fish oil is well mixed, adds the pure water of 20 times of mass ratioes of material after mixing;
(5)Ultrasound-assisted enzymolysis:The amylase of feed liquid mass ratio 3~5%, 1~2% cellulase, 1~2% pectase are added, Under ultrasonic assistant action condition, 40~60 DEG C of 3~5h of enzymolysis;
(6)Filtering:Separation of solid and liquid, remove Chinese herbal medicine residue;
(7)Concentration:Feed liquid after filtering is concentrated into pasty state;
(8)Compounding:Filefish fish oil is well mixed with the extract after concentration;
(9)Drying and crushing:Crushed after being dried, cross 200 mesh sieves;
(10)Sterilizing:Sterilized with cobalt -60;
(11)Filling capsule:It is filling in clean indoor No. 0 capsule;
(12)Shaped article:Capsule bottling after will be filling, labeling, coding produce the filefish fish oil with beneficial spleen stomach invigorating effect and protected Strong capsule.
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CN111011852A (en) * 2019-12-26 2020-04-17 吉林大学 Preparation method of ginseng instant food with liver protection function

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CN1279957A (en) * 2000-03-06 2001-01-17 辽阳鸿宇制药有限公司 Use of puffer liver oil in preparing food for curing poisonous drug dependence
CN1895285A (en) * 2006-06-29 2007-01-17 董玉明 Medicinal use of fugu cod liver oil
CN101066340A (en) * 2007-05-16 2007-11-07 苏振芳 Compound externally applied tetrodotoxin ointment and its prepn
CN101182448A (en) * 2007-11-23 2008-05-21 大连工业大学 Method for preparing non-toxic globefish fin wine
CN101279037A (en) * 2007-04-03 2008-10-08 北京亚东生物制药有限公司 Composition for curing impairment by overeating, preparation and quality control method
CN103977338A (en) * 2014-06-04 2014-08-13 天津太平洋制药有限公司 Traditional Chinese medicine for strengthening spleen and stomach
JP5663523B2 (en) * 2012-04-27 2015-02-04 株式会社萬坊 Method for producing pufferfish liver oil
CN104434982A (en) * 2015-01-06 2015-03-25 刘学民 Medicinal globefish oil making method

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101002051B1 (en) * 2003-08-14 2010-12-17 포항공과대학교 산학협력단 A method for producing a functional food material from a puffer by using batch distillation

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279957A (en) * 2000-03-06 2001-01-17 辽阳鸿宇制药有限公司 Use of puffer liver oil in preparing food for curing poisonous drug dependence
CN1895285A (en) * 2006-06-29 2007-01-17 董玉明 Medicinal use of fugu cod liver oil
CN101279037A (en) * 2007-04-03 2008-10-08 北京亚东生物制药有限公司 Composition for curing impairment by overeating, preparation and quality control method
CN101066340A (en) * 2007-05-16 2007-11-07 苏振芳 Compound externally applied tetrodotoxin ointment and its prepn
CN101182448A (en) * 2007-11-23 2008-05-21 大连工业大学 Method for preparing non-toxic globefish fin wine
JP5663523B2 (en) * 2012-04-27 2015-02-04 株式会社萬坊 Method for producing pufferfish liver oil
CN103977338A (en) * 2014-06-04 2014-08-13 天津太平洋制药有限公司 Traditional Chinese medicine for strengthening spleen and stomach
CN104434982A (en) * 2015-01-06 2015-03-25 刘学民 Medicinal globefish oil making method

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