CN105418510B - 一种(e)-4-(咪唑基甲基)肉桂酸甲酯的制备方法 - Google Patents
一种(e)-4-(咪唑基甲基)肉桂酸甲酯的制备方法 Download PDFInfo
- Publication number
- CN105418510B CN105418510B CN201511002015.2A CN201511002015A CN105418510B CN 105418510 B CN105418510 B CN 105418510B CN 201511002015 A CN201511002015 A CN 201511002015A CN 105418510 B CN105418510 B CN 105418510B
- Authority
- CN
- China
- Prior art keywords
- methyl
- methyl cinnamate
- cinnamate
- imidazolyl
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201511002015.2A CN105418510B (zh) | 2015-12-29 | 2015-12-29 | 一种(e)-4-(咪唑基甲基)肉桂酸甲酯的制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201511002015.2A CN105418510B (zh) | 2015-12-29 | 2015-12-29 | 一种(e)-4-(咪唑基甲基)肉桂酸甲酯的制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105418510A CN105418510A (zh) | 2016-03-23 |
CN105418510B true CN105418510B (zh) | 2018-05-15 |
Family
ID=55497115
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201511002015.2A Active CN105418510B (zh) | 2015-12-29 | 2015-12-29 | 一种(e)-4-(咪唑基甲基)肉桂酸甲酯的制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105418510B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114436964A (zh) * | 2020-10-16 | 2022-05-06 | 赤峰经方医药技术开发有限责任公司 | 一种奥扎格雷的连续制备方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006131624A (ja) * | 2004-10-07 | 2006-05-25 | Ono Pharmaceut Co Ltd | オザグレルナトリウムを含有する安定なプレミクスト注射剤 |
CN102241632A (zh) * | 2010-05-10 | 2011-11-16 | 辽宁诺康医药有限公司 | 一种奥扎格雷原料药的制备方法 |
CN102417482A (zh) * | 2011-12-31 | 2012-04-18 | 西藏易明西雅生物医药科技有限公司 | 一种奥扎格雷乙酯或奥扎格雷甲酯的合成方法 |
CN102558061A (zh) * | 2011-12-31 | 2012-07-11 | 北京易明康元医药科技有限公司 | 一种奥扎格雷合成方法 |
-
2015
- 2015-12-29 CN CN201511002015.2A patent/CN105418510B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006131624A (ja) * | 2004-10-07 | 2006-05-25 | Ono Pharmaceut Co Ltd | オザグレルナトリウムを含有する安定なプレミクスト注射剤 |
CN102241632A (zh) * | 2010-05-10 | 2011-11-16 | 辽宁诺康医药有限公司 | 一种奥扎格雷原料药的制备方法 |
CN102417482A (zh) * | 2011-12-31 | 2012-04-18 | 西藏易明西雅生物医药科技有限公司 | 一种奥扎格雷乙酯或奥扎格雷甲酯的合成方法 |
CN102558061A (zh) * | 2011-12-31 | 2012-07-11 | 北京易明康元医药科技有限公司 | 一种奥扎格雷合成方法 |
Also Published As
Publication number | Publication date |
---|---|
CN105418510A (zh) | 2016-03-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN107253912B (zh) | 氰氟草酯的合成方法 | |
CN110845502A (zh) | 一种7-溴吡咯并[2,1-f][1,2,4]噻嗪-4-胺的制备方法 | |
CN105237560A (zh) | 一种lzc696中间体及其合成方法 | |
CN104370791B (zh) | 一种左乙拉西坦的纯化方法 | |
CN105254575B (zh) | 一种磺胺嘧啶的合成方法 | |
CN105418510B (zh) | 一种(e)-4-(咪唑基甲基)肉桂酸甲酯的制备方法 | |
CN106397515A (zh) | 一种改良的索菲布韦制备方法 | |
CN103923028B (zh) | 一种缬沙坦甲酯的制备方法 | |
CN103396406B (zh) | 一种坎地沙坦酯的制备方法 | |
CN102212343A (zh) | 一种溴化锂吸收式循环工质的制备方法 | |
CN103554049B (zh) | 一种制备缬沙坦的方法 | |
CN104910032A (zh) | 一种苯胺基乙酸盐的制备方法 | |
CN103588765A (zh) | 阿齐沙坦酯或其盐的合成方法及其中间体和中间体的合成方法 | |
CN104961724B (zh) | 一种获得高纯度地氯雷他定的先进生产工艺 | |
CN104151170A (zh) | 4-硝基苯乙胺盐酸盐及其制备方法 | |
CN105949176B (zh) | 一种来那替尼的纯化方法 | |
CN103086900B (zh) | 一种在醇相中进行循环环保法生产甘氨酸的方法 | |
CN107935897A (zh) | 邻甲苯基硫脲的合成工艺 | |
CN111303172B (zh) | 一种制备依托度酸甲酯的方法 | |
CN105764882B (zh) | 合成非离子x射线造影剂的备选乙酰化方法 | |
CN108997236B (zh) | 一种阿那曲唑杂质的制备方法 | |
CN105481771B (zh) | 一种奥扎格雷中间体(e)-4-(咪唑基甲基)肉桂酸甲酯的制备工艺 | |
CN106397240A (zh) | 2-卤代乙酰胺的合成方法 | |
CN103724248A (zh) | 维格列汀工艺杂质的制备方法 | |
CN109160890A (zh) | 一种spe的合成方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20190221 Address after: 253100 Shandong Province Plain of Dezhou City Economic Development Zone north two Ring Road West first northbound Shandong Yunjia Pharmaceutical Co. Ltd. Patentee after: SHANDONG CHENGHUI SHUANGDA PHARMACEUTICAL CO.,LTD. Address before: 250101 2350 development road, hi tech Development Zone, Ji'nan, Shandong Patentee before: JINAN CHENGHUISHUANGDA CHEMICAL INDUSTRY Co.,Ltd. |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A preparation method of methyl (E) -4- (imidazolyl methyl) cinnamate Effective date of registration: 20220616 Granted publication date: 20180515 Pledgee: Shandong Pingyuan Rural Commercial Bank Co.,Ltd. Pledgor: SHANDONG CHENGHUI SHUANGDA PHARMACEUTICAL CO.,LTD. Registration number: Y2022980007784 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20230726 Granted publication date: 20180515 Pledgee: Shandong Pingyuan Rural Commercial Bank Co.,Ltd. Pledgor: SHANDONG CHENGHUI SHUANGDA PHARMACEUTICAL CO.,LTD. Registration number: Y2022980007784 |