CN105319379A - Full-automatic analyzer for immunity - Google Patents
Full-automatic analyzer for immunity Download PDFInfo
- Publication number
- CN105319379A CN105319379A CN201510653257.1A CN201510653257A CN105319379A CN 105319379 A CN105319379 A CN 105319379A CN 201510653257 A CN201510653257 A CN 201510653257A CN 105319379 A CN105319379 A CN 105319379A
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- China
- Prior art keywords
- motor
- lath
- slide rail
- synchronizing wheel
- slide block
- Prior art date
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Links
- 230000036039 immunity Effects 0.000 title abstract description 5
- 230000007246 mechanism Effects 0.000 claims abstract description 93
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 58
- 238000005096 rolling process Methods 0.000 claims description 27
- 238000012546 transfer Methods 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 20
- 238000012360 testing method Methods 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 10
- 230000012447 hatching Effects 0.000 claims description 8
- 238000001816 cooling Methods 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- 238000009826 distribution Methods 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 2
- 238000011534 incubation Methods 0.000 abstract description 4
- 238000007689 inspection Methods 0.000 abstract description 2
- 238000011010 flushing procedure Methods 0.000 abstract 4
- 230000003139 buffering effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 description 9
- 238000004458 analytical method Methods 0.000 description 3
- 239000000376 reactant Substances 0.000 description 3
- 238000013475 authorization Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000010355 oscillation Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002558 medical inspection Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
Abstract
The invention relates to the technical field of medical treatment inspection equipment, in particular to a full-automatic analyzer for immunity. The full-automatic analyzer for immunity comprises a shell, a rack body, a sample area arranged on the rack body, a batten feeding mechanism, a buffering area, an incubation mechanism, a four-station mechanism, a detecting mechanism and a control system. The four-station mechanism comprises a four-station rotating table, a rotating table installing table, a flushing module and a reagent adding module. A rotating motor is arranged on the lower surface of the rotating table installing table and drives the four-station rotating table to rotate. A lifting motor is arranged on the rack body to drive the flushing module to move vertically. Four batten inserting grooves distributed in a 90-degree mode are formed in the upper surface of the four-station rotating table. The reagent adding module and the flushing module are arranged above the four-station rotating table side by side. The flushing module is provided with a row of adding needles and a row of sucking needles perpendicular to the adding needles. The reagent adding module comprises a first motor and a reagent adding needle.
Description
Technical field
The present invention relates to technical field of medical inspection equipment, specifically immune fully-automatic analyzer.
Background technology
Current existing immunity analysis instrument is generally used for reading 96 hole or 48 hole microwell plates, so-called 96 holes or 48 hole microwell plates and plank comprise 96 or 48 reaction cup, each sample detected that needs is placed in a reaction cup, use one monoblock 96 hole or 48 hole microwell plates are needed equally when needing the sample size detected to only have when several or tens, therefore a large amount of wastes is caused, and the time of the microwell plate in 96 holes or 48 holes needed for application of sample first hole to last hole is longer, therefore the consistance of result is had a certain impact, such as, be the patent of CN203490229U at Authorization Notice No. disclosed in 19 days March in 2014, disclose a kind of accurate automatic board-like immunity analysis instrument, primarily of casing, placement unit, hatch unit, cleaning unit, substrate filling unit, optical detection unit and system operations control module composition, achieve reactant liquor incubation, reactant liquor washes plate, reactant liquor adds the whole process of substrate measurement from note, two pieces of microwell plates can be placed during operation simultaneously.On the other hand, on market, existing single reaction cup is as a transmission, detecting unit, also can detect when only having a sample, but, the efficiency of this kind of single detection is not high enough, and when sample size is large, detection time is long, be not suitable for inspection in enormous quantities, such as, be the patent of CN102183639B at Authorization Notice No. disclosed in 5 days June in 2013, disclose a kind of Full-automatic chemiluminescence immunoassay analysis meter, by reaction cup feed system, three-dimensional mobile application of sample module, sample area, reagent area, pump group, control system forms, that single reaction cup carries out transmission detection.
Summary of the invention
The invention provides that a kind of structure is simple, volume compact, immune fully-automatic analyzer easy and simple to handle.
The present invention is achieved through the following technical solutions:
A kind of immune fully-automatic analyzer, comprise housing, support body, be located at the sample area on support body, lath feed mechanism, buffer zone, hatch mechanism, four station mechanisms, testing agency and control system, described housing is covered in outside described support body, side, described sample area is provided with sample suction nozzle, sample application arm is provided with on the left of described support body, right side is provided with reagent pipetting volume arm, described mechanism of hatching is located at lath feed mechanism side, described buffer zone is located at described lath feed mechanism and is hatched between mechanism, described four station mechanisms are located at and are hatched mechanism front, described testing agency is located at hatches mechanism rear, reagent area is provided with below described four station mechanisms, described lath feed mechanism comprises the first pusher arms, described first pusher arms is provided with the first push rod, described four station mechanisms and hatch mechanism side and be provided with the second pusher arms by column, described second pusher arms moves up and down along column, described second pusher arms is provided with lath transfer handgrip, described lath transfer handgrip moves forward and backward along the second pusher arms, described lath transfer handgrip is provided with the second push rod, described second push rod moves left and right along lath transfer handgrip, reagent suction nozzle is provided with on the right side of described second pusher arms, described four station mechanisms comprise four work position rotation tables, turntable erecting bed, wash module and reagent adding module, described turntable erecting bed lower surface is provided with electric rotating machine, described four work position rotation tables are driven to rotate, described support body is provided with lifting motor, drive wash module moves up and down, described four work position rotation table upper surfaces are provided with the lath slot of four distributions in an angle of 90 degrees, described reagent adding module and wash module are located at above described four work position rotation tables side by side, described wash module is provided with a row and adds pin and a row and add the perpendicular suction spindle of pin, described reagent adding module comprises the first motor and reagent adding pin, described reagent adding pin is slidably connected by the first slide rail and the first slide block and described four work position rotation tables, described reagent adding pin is connected with described first motor by the first Timing Belt, described lath feed mechanism, hatch mechanism, testing agency, electric rotating machine, lifting motor and the first motor are electrically connected with described control system respectively, described immune fully-automatic analyzer also involving vibrations mechanism, described vibrating mechanism comprises holder, at least one vibrating motor, at least one diluted cup and at least one diluted cup mount pad, described vibrating motor is fixed on the lower surface of described holder, the output shaft of described vibrating motor passes described holder and exposes described holder upper surface, the output shaft of described vibrating motor is provided with an excentric shaft, the lower surface of described diluted cup mount pad is provided with a fixed block, the center of described fixed block is provided with a manhole, described excentric shaft is located in described manhole, described diluted cup is located on the upper surface of described diluted cup mount pad, four rubber blankets are provided with between the lower surface of described diluted cup mount pad and the upper surface of described holder, the lower end of described rubber blanket is fixed on described holder, the lateral surface of described holder is positioned at each diluted cup side and is respectively provided with a sensor, and the height of described sensor is higher than the height of described diluted cup mount pad, described lath feed mechanism comprises riser, base plate, lath, lath frame, storehouse and plate taking-out mechanism, and be provided with some laminate bar framves in described storehouse in the vertical, described lath frame is provided with some lath grooves, and described lath is located in described lath groove, one of them side of described base plate is provided with the first slide rail, the lower surface of described base plate is provided with the first motor, described first slide rail is provided with the first slide block, described first slide block and the first slide rail are slidably connected, described first slide block is connected with described first motor by the first Timing Belt, described first slide block is provided with the first pusher arms, described first pusher arms is provided with the first push rod, second motor and the second slide rail, described second slide rail is provided with the second slide block be slidably connected with it, and be connected with described second motor by the second Timing Belt, described first push rod is located on described second slide block, another side of described base plate is provided with the 3rd slide rail, the lower surface of described base plate is provided with the 3rd motor, described 3rd slide rail is provided with the 3rd slide block, described 3rd slide block and the 3rd slide rail are slidably connected, described 3rd slide block is connected with described 3rd motor by the 3rd Timing Belt, and described buffer zone is located on described 3rd slide block, described riser is provided with the 4th motor and two articles of the 4th slide rails be parallel to each other, article described two, be provided with the first screw mandrel between the 4th slide rail, described 4th motor is connected by the 4th Timing Belt one end with described first screw mandrel, described first screw mandrel is provided with Four-slider, described Four-slider and described 4th slide rail are slidably connected, and described base plate is fixed on described Four-slider, described column is provided with the 6th motor and two articles of the 6th slide rails be parallel to each other, article described two, be provided with the second screw mandrel between the 6th slide rail, described 6th motor is connected by the 6th Timing Belt one end with described second screw mandrel, described second screw mandrel is provided with the 6th slide block, described 6th slide block and described 6th slide rail are slidably connected, and described second pusher arms is fixed on described 6th slide block, described second pusher arms is provided with the 7th motor, and described lath transfer handgrip is connected with the 7th motor by the 7th Timing Belt, described lath transfer handgrip is provided with the 8th motor, and described second push rod is connected with the 8th motor by the 8th Timing Belt, described mechanism of hatching comprises shell, fixed head, vibration motor and lath frame, described fixed head is provided with two eccentrically weighted shafts arranged in parallel, described vibration motor drives described two eccentrically weighted shafts to rotate, described eccentrically weighted shaft is provided with some contiguous blocks, described lath is set up between two pieces of contiguous blocks on two eccentrically weighted shafts, described eccentrically weighted shaft rotates relative to contiguous block, described lath frame is driven to vibrate in the horizontal plane, the lower surface of described lath frame is provided with heating plate, it is outside that described shell is located at described lath frame, the front and back sides of described shell is by a rolling door sealing, described rolling door is provided with a transversal slotting, described fixed head is provided with rolling door motor, transversal slotting on described rolling door is moved up and down by rolling door motor, the lower surface of each lath frame is provided with temperature sensor.
Described plate taking-out mechanism comprises handgrip, the 5th motor, the 5th slide rail and the 5th slide block, described 5th motor is located on the lower surface of described base plate, described 5th slide rail is located on the upper surface of described base plate, described 5th slide block is located on described 5th slide rail, and be slidably connected with the 5th slide rail, described 5th motor is connected with described 5th slide block by the 5th Timing Belt.
Described buffer zone comprises lath frame and clamping piece, described lath frame comprises base and is located on base upper surface some blend stop arranged in parallel, the upper surface of described blend stop is provided with some jacks, opposite position place on the lower surface of described clamping piece is provided with some inserted links, described inserted link inserts in described jack, described base is provided with some through holes, described through hole is between two adjacent blend stops, the lower surface of described base is provided with a cooling piece, the width of described clamping piece is greater than the width of described blend stop, described lath is located between described two adjacent blend stops, and described two adjacent clamping pieces compress the both sides at described lath upper opening place respectively.
The side of a described vibration motor eccentrically weighted shaft located therein, the first synchronizing wheel and the second synchronizing wheel is provided with near the lower end of the eccentrically weighted shaft of described vibration motor, the lower end of another root eccentrically weighted shaft is provided with the 3rd synchronizing wheel, the output terminal of described vibration motor is provided with the 4th synchronizing wheel, described 4th synchronizing wheel is connected with described first synchronizing wheel by the 9th Timing Belt, and described second synchronizing wheel is connected with described 3rd synchronizing wheel by the tenth Timing Belt.
Described fixed head is provided with lower rotary shaft, the lower end of described rolling door twists on described lower rotary shaft, the inside surface of described shell is provided with rotating shaft, the upper end of described rolling door twists in described upper rotating shaft, the output terminal of described rolling door motor is provided with the 5th synchronizing wheel, the two ends of described lower rotary shaft are respectively equipped with the 6th synchronizing wheel and the 7th synchronizing wheel, one end of described upper rotating shaft is provided with the 8th synchronizing wheel, described 5th synchronizing wheel is connected by the 11 Timing Belt with the 6th synchronizing wheel, and described 7th synchronizing wheel is connected by the 12 Timing Belt with the 8th synchronizing wheel.
A liquid, B liquid and stop buffer is provided with in described reagent area, reaction reagent district is provided with on the right side of described reagent suction nozzle, the side of described sample area is provided with Article 1 ink recorder, in described storehouse, every laminate bar frame side is equipped with an Article 2 ink recorder, and described Article 1 ink recorder and Article 2 ink recorder are electrically connected with control system respectively.Place the various lath frame for detecting different sample in described storehouse, which kind of sample the scanning of Article 1 ink recorder is confirmed to be, and then determines to adopt which kind of lath frame by Article 2 ink recorder.
The beneficial effect that the present invention brings is:
In the present invention, described immune fully-automatic analyzer support does not shut down loading, namely the lath frame that placed lath can add from storehouse continuously by user in non-stop-machine situation, taken out by plate taking-out mechanism again, and at buffer zone place by sample application arm application of sample, after application of sample, lath moves into and hatches mechanism and carry out incubation and oscillation treatment, lath is moved on on four station mechanisms by lath transfer handgrip and the second push rod and carries out the operation of suction mix reagent adding afterwards, described lath immigration testing agency carries out detecting and is discharged in pail for used dressings by the lath after having detected afterwards, above whole process can be carried out continuously under non-stop-machine state, which improves detection efficiency, and ensure that the accuracy of detection, on the other hand, the hole microwell plate in 96 holes or 48 holes is resolved into single lath and enters detection, detect more flexible than the hole microwell plate in use 96 hole or 48 holes, and cost-saving, single lath enters flowing water when detecting, from first reaction cup application of sample or reagent adding short to the time interval of last reaction cup application of sample or reagent adding, and then testing result is more accurate, relative, more increase than single reaction cup detection efficiency, operative is easier.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, the present invention is described in further detail.
Fig. 1 is the structural representation of immune fully-automatic analyzer of the present invention.
Fig. 2 is the structural representation that immune fully-automatic analyzer of the present invention removes housing.
Fig. 3 is the structural representation in four station mechanism fronts of the present invention.
Fig. 4 is the structural representation of four station mechanism reverse side of the present invention.
Fig. 5 is the structural representation in vibrating mechanism front of the present invention.
Fig. 6 is the structural representation of vibrating mechanism reverse side of the present invention.
Fig. 7 is the structural representation in lath feed mechanism front of the present invention.
Fig. 8 is the structural representation of lath feed mechanism reverse side of the present invention.
Fig. 9 is the structural representation in front, buffer zone of the present invention.
Figure 10 is the structural representation of buffer zone of the present invention reverse side.
Figure 11 is four station mechanisms of the present invention, hatches the structural representation of mechanism and testing agency.
Figure 12 is structural representation of hatching mechanism of the present invention.
Figure 13 of the present inventionly hatches the structural representation that mechanism removes shell and rolling door.
Figure 14 of the present inventionly hatches the structural representation that mechanism removes shell.
The label that in figure, component names is corresponding is as follows:
1, housing; 2, support body; 3, sample area; 4, testing agency; 5, sample suction nozzle; 6, sample application arm; 7, reagent pipetting volume arm; 8, the first pusher arms; 9, the first push rod; 10, column; 11, the second pusher arms; 12, lath transfer handgrip; 13, the second push rod; 14, reagent suction nozzle; 15, four work position rotation tables; 16, turntable erecting bed; 17, wash module; 18, electric rotating machine; 19, lifting motor; 20, lath slot; 21, pin is added; 22, suction spindle; 23, reagent adding motor; 24, reagent adding pin; 25, reagent adding slide rail; 26, reagent adding slide block; 27, reagent adding Timing Belt; 28, holder; 29, vibrating motor; 30, diluted cup mount pad; 31, diluted cup; 32, excentric shaft; 33, fixed block; 34, manhole; 35, rubber blanket; 36, sensor; 37, riser; 38, base plate; 39, lath; 40, lath frame; 41, storehouse; 42, lath groove; 43, the first slide rail; 44, the first motor; 45, the first slide block; 46, the first Timing Belt; 47, the second motor; 48, the second slide rail; 49, the second Timing Belt; 50, the 3rd slide rail; 51, the 3rd motor; 52, the 3rd slide block; 53, the 3rd Timing Belt; 54, the 4th motor; 55, the 4th slide rail; 56, screw mandrel; 57, the 4th Timing Belt; 58, Four-slider; 59, handgrip; 60, the 5th motor; 61, the 5th slide rail; 62, the 5th slide block; 63, clamping piece; 64, base; 65, blend stop; 66, jack; 67, inserted link; 68, through hole; 69, cooling piece; 70, the 6th motor; 71, the 6th slide rail; 72, the second screw mandrel; 73, the 6th Timing Belt; 74, the 6th slide block; 75, the 7th motor; 76, the 7th Timing Belt; 77, the 8th motor; 78, the 8th Timing Belt; 79, shell; 80, fixed head; 81, vibrating motor; 82, eccentrically weighted shaft; 83, contiguous block; 84, heating plate; 85, rolling door; 86, transversal slotting; 87, rolling door motor; 88, temperature sensor; 89, the first synchronizing wheel; 90, the second synchronizing wheel; 91, the 8th synchronizing wheel; 92, the 4th synchronizing wheel; 93, the 9th Timing Belt; 94, the tenth Timing Belt; 95, lower rotary shaft; 96, upper rotating shaft; 97, the 5th synchronizing wheel; 98, the 6th synchronizing wheel; 99, the 7th synchronizing wheel; 100, the 8th synchronizing wheel; 101, the 11 Timing Belt; 102, the 12 Timing Belt; 103, A liquid; 104, B liquid; 105, stop buffer; 106, reaction reagent district; 107, Article 1 ink recorder; 108, Article 2 ink recorder; 109, lath station is picked and placeed; 110, first plate station is washed; 111, second plate station is washed; 112, A/B liquid station is added.
Embodiment
Below in conjunction with drawings and Examples, the present invention is described in further detail:
As the embodiment of immune fully-automatic analyzer of the present invention, as Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, Fig. 7, Fig. 8, Fig. 9, Figure 10, Figure 11, Figure 12, shown in Figure 13 and Figure 14, comprise housing 1, support body 2, be located at the sample area 3 on support body 2, lath feed mechanism, buffer zone, hatch mechanism, four station mechanisms, testing agency 4 and control system (not shown), described housing 1 is covered in outside described support body 2, side, described sample area 3 is provided with sample suction nozzle 5, sample application arm 6 is provided with on the left of described support body 2, right side is provided with reagent pipetting volume arm 7, described mechanism of hatching is located at lath feed mechanism side, described buffer zone 3 is located at described lath feed mechanism and is hatched between mechanism, described four station mechanisms are located at and are hatched mechanism front, described testing agency 4 is located at hatches mechanism rear, reagent area is provided with below described four station mechanisms, described lath feed mechanism comprises the first pusher arms 8, described first pusher arms 8 is provided with the first push rod 9, described four station mechanisms and hatch mechanism side and be provided with the second pusher arms 11 by column 10, described second pusher arms 11 moves up and down along column, described second pusher arms 11 is provided with lath transfer handgrip 12, described lath transfer handgrip 12 moves forward and backward along the second pusher arms 11, described lath transfer handgrip 12 is provided with the second push rod 13, described second push rod 13 moves left and right along lath transfer handgrip 12, reagent suction nozzle 14 is provided with on the right side of described second pusher arms 11, described four station mechanisms comprise four work position rotation tables 15, turntable erecting bed 16, wash module 17 and reagent adding module, described turntable erecting bed 16 lower surface is provided with electric rotating machine 18, described four work position rotation tables 16 are driven to rotate, described support body 2 is provided with lifting motor 19, wash module 17 is driven to move up and down, described four work position rotation table 16 upper surfaces are provided with the lath slot 20 of four distributions in an angle of 90 degrees, described reagent adding module and wash module 17 are located at above described four work position rotation tables 16 side by side, described wash module 17 is provided with a row and adds pin 21 and a row and add the perpendicular suction spindle of pin 22, described reagent adding module comprises reagent adding motor 23 and reagent adding pin 24, described reagent adding pin 24 is slidably connected with described four work position rotation tables 16 by reagent adding slide rail 25 and reagent adding slide block 26, described reagent adding pin 24 is connected with described reagent adding motor 23 by reagent adding Timing Belt 27, described lath feed mechanism, hatch mechanism, testing agency 4, electric rotating machine 18, lifting motor 19 and reagent adding motor 23 are electrically connected with described control system respectively.
In the present embodiment, described immune fully-automatic analyzer also involving vibrations mechanism, described vibrating mechanism comprises holder 28, two vibrating motors 29, two diluted cups 31 and two diluted cup mount pads 30, described vibrating motor 29 is fixed on the lower surface of described holder 28, the output shaft of described vibrating motor 29 passes described holder 28 and exposes described holder 28 upper surface, the output shaft of described vibrating motor 29 is provided with an excentric shaft 32, the lower surface of described diluted cup mount pad 30 is provided with a fixed block 33, the center of described fixed block 33 is provided with a manhole 34, described excentric shaft 32 is located in described manhole 34, described diluted cup 31 is located on the upper surface of described diluted cup mount pad 30, four rubber blankets 35 are provided with between the lower surface of described diluted cup mount pad 30 and the upper surface of described holder 28, the lower end of described rubber blanket 35 is fixed on described holder 28, the lateral surface of described holder 28 is positioned at each diluted cup 31 side and is respectively provided with a sensor 36, and the height of described sensor 36 is higher than the height of described diluted cup mount pad 30.
In the present embodiment, described lath feed mechanism comprises riser 37, base plate 38, lath 39, lath frame 40, storehouse 41 and plate taking-out mechanism, ten laminate bar framves 40 are provided with in the vertical in described storehouse 41, described lath frame 40 is provided with 12 lath grooves 42, and described lath 39 is located in described lath groove 42, one of them side of described base plate 38 is provided with the first slide rail 43, the lower surface of described base plate 38 is provided with the first motor 44, described first slide rail 43 is provided with the first slide block 45, described first slide block 45 and the first slide rail 43 are slidably connected, described first slide block 45 is connected with described first motor 44 by the first Timing Belt 46, described first slide block 45 is provided with the first pusher arms 8, described first pusher arms 8 is provided with the first push rod 9, second motor 47 and the second slide rail 48, described second slide rail 48 is provided with the second slide block (not shown) be slidably connected with it, and be connected with described second motor 47 by the second Timing Belt 49, described first push rod 9 is located on described second slide block, another side of described base plate 38 is provided with the 3rd slide rail 50, the lower surface of described base plate 38 is provided with the 3rd motor 51, described 3rd slide rail 50 is provided with the 3rd slide block 52, described 3rd slide block 52 and the 3rd slide rail 50 are slidably connected, described 3rd slide block 52 is connected with described 3rd motor 51 by the 3rd Timing Belt 53, and described buffer zone is located on described 3rd slide block 52, described riser 37 is provided with the 4th motor 54 and two articles of the 4th slide rails 55 be parallel to each other, article described two, be provided with the first screw mandrel 56 between the 4th slide rail 55, described 4th motor 54 is connected by the 4th Timing Belt 57 one end with described first screw mandrel 56, described first screw mandrel 56 is provided with Four-slider 58, described Four-slider 58 is slidably connected with described 4th slide rail 55, and described base plate 38 is fixed on described Four-slider 58.
In the present embodiment, described plate taking-out mechanism comprises handgrip 59, the 5th motor 60, the 5th slide rail 61 and the 5th slide block 62, described 5th motor 60 is located on the lower surface of described base plate 38, described 5th slide rail 61 is located on the upper surface of described base plate 38, described 5th slide block 62 is located on described 5th slide rail 61, and be slidably connected with the 5th slide rail 61, described 5th motor 60 is connected with described 5th slide block 62 by the 5th Timing Belt (not shown).
In the present embodiment, described buffer zone comprises lath frame 40 and clamping piece 63, described lath frame 40 comprises base 64 and is located on base upper surface six blend stop 65 arranged in parallel, the upper surface of described blend stop 65 is provided with three jacks 66, opposite position place on the lower surface of described clamping piece 63 is provided with three inserted links 67, described inserted link 67 inserts in described jack 66, described base 64 is provided with eight through holes 68, described through hole 68 is between two adjacent blend stops, the lower surface of described base 64 is provided with a cooling piece 69, the width of described clamping piece 63 is greater than the width of described blend stop 65, described lath 39 is located between described two adjacent blend stops 65, and described two adjacent clamping pieces 63 compress the both sides at described lath 39 upper opening place respectively.
In the present embodiment, described column 10 is provided with the 6th motor 70 and two articles of the 6th slide rails 71 be parallel to each other, article described two, be provided with the second screw mandrel 72 between the 6th slide rail 71, described 6th motor 70 is connected by the 6th Timing Belt 73 one end with described second screw mandrel 72, described second screw mandrel 72 is provided with the 6th slide block 74, described 6th slide block 74 is slidably connected with described 6th slide rail 71, and described second pusher arms 11 is fixed on described 6th slide block 74; Described second pusher arms 11 is provided with the 7th motor 75, and described lath transfer handgrip 12 is connected with the 7th motor 75 by the 7th Timing Belt 76; Described lath transfer handgrip 12 is provided with the 8th motor 77, and described second push rod 13 is connected with the 8th motor 77 by the 8th Timing Belt 78.
In the present embodiment, described mechanism of hatching comprises shell 79, fixed head 80, vibration motor 81 and lath frame 40, described fixed head 80 is provided with two eccentrically weighted shafts 82 arranged in parallel, described vibration motor 81 drives described two eccentrically weighted shafts 82 to rotate, described eccentrically weighted shaft 82 is provided with eight contiguous blocks 83, described lath frame 40 is located between two pieces of contiguous blocks 83 on two eccentrically weighted shafts 82, described eccentrically weighted shaft 82 rotates relative to contiguous block 83, described lath frame 40 is driven to vibrate in the horizontal plane, the lower surface of described lath frame 40 is provided with heating plate 84, it is outside that described shell 79 is located at described lath frame 40, the front and back sides of described shell 79 is sealed by a rolling door 85, described rolling door 85 is provided with a transversal slotting 86, described fixed head 80 is provided with rolling door motor 87, transversal slotting 86 on described rolling door 85 is moved up and down by rolling door motor 87, the lower surface of each lath frame 40 is provided with temperature sensor 88.
In the present embodiment, the side of described vibration motor 81 eccentrically weighted shaft 82 located therein, the first synchronizing wheel 89 and the second synchronizing wheel 90 is provided with near the lower end of the eccentrically weighted shaft 82 of described vibration motor 81, the lower end of another root eccentrically weighted shaft 82 is provided with the 3rd synchronizing wheel 91, the output terminal of described vibration motor 81 is provided with the 4th synchronizing wheel 92, described 4th synchronizing wheel 92 is connected with described first synchronizing wheel 89 by the 9th Timing Belt 93, and described second synchronizing wheel 90 is connected with described 3rd synchronizing wheel 91 by the tenth Timing Belt 94.
In the present embodiment, described fixed head 80 is provided with lower rotary shaft 95, the lower end of described rolling door 85 twists on described lower rotary shaft 95, the inside surface of described shell 79 is provided with rotating shaft 96, the upper end of described rolling door 85 twists in described upper rotating shaft 96, the output terminal of described rolling door motor 87 is provided with the 5th synchronizing wheel 97, the two ends of described lower rotary shaft 95 are respectively equipped with the 6th synchronizing wheel 98 and the 7th synchronizing wheel 99, one end of described upper rotating shaft 95 is provided with the 8th synchronizing wheel 100, described 5th synchronizing wheel 97 is connected by the 11 Timing Belt 101 with the 6th synchronizing wheel 98, described 7th synchronizing wheel 99 is connected by the 12 Timing Belt 102 with the 8th synchronizing wheel 100.
In the present embodiment, A liquid 103, B liquid 104 and stop buffer 105 is provided with in described reagent area, reaction reagent district 106 is provided with on the right side of described reagent suction nozzle 14, the side of described sample area 3 is provided with Article 1 ink recorder 107, in described storehouse 41, every laminate bar frame 40 side is equipped with an Article 2 ink recorder 108, and described Article 1 ink recorder 107 and Article 2 ink recorder 108 are electrically connected with control system respectively.Place the various lath frame 40 for detecting different sample in described storehouse 41, which kind of sample Article 1 ink recorder 107 scanning is confirmed to be, and then determines to adopt which kind of lath frame 40 by Article 2 ink recorder 108.
Principle of work is as follows:
The lath frame 40 that placed lath 39 is put into storehouse 41 by user, plate taking-out mechanism can be continued through take out in non-stop-machine situation, and at buffer zone place by sample application arm 6 application of sample, after application of sample, lath 39 moves into and hatches mechanism and carry out incubation and oscillation treatment, when lath 39 shifts in the corresponding lath slot 20 of handgrip 12 by lath transfer handgrip 12 from hatching to be delivered to four work position rotation tables 15 by the second push rod 13 after mechanism takes out with lath, now for picking and placeing lath station 109, under the drive of electric rotating machine 18, four work position rotation table 15 dextrorotations turn 90 degrees, arrive first and wash plate station 110, now, put into again a lath 39, 90-degree rotation again, when first lath 39 arrive second wash plate station 111 time, put into again a lath 39, four work position rotation tables 15 90-degree rotation again, when first lath 39 arrival adds A/B liquid station 112, put into a lath 39 again, four work position rotation tables 90-degree rotation again, this moment, first lath 39 is got back to and is picked and placeed lath station 109, taken out in lath slot 20 by lath transfer handgrip 12 again, be put into and hatch in mechanism or detection machine 4 structure, carry out next step operation.
Certainly, eight layers or Floor 12 or 14 laminate bar framves can be also provided with in described storehouse in the vertical; Described lath frame also can be provided with eight or ten or 14 lath grooves; Described bumper bracket also can be provided with four or six or eight the lath dashpots be parallel to each other; Described base also can be arranged four or five or eight or ten or 12 blend stops; The upper surface of described blend stop also can be arranged two or four or five jacks, corresponding, described clamping piece is arranged two or four or five inserted links; Described base also can be arranged four or six or ten through holes; Described vibrating mechanism also can comprise three or four or five vibrating motors, three or four or five bases and three or four or five diluted cups, each motor is connected with a diluted cup mount pad respectively, each diluted cup mount pad is respectively equipped with a diluted cup, corresponding, comprise three or four or five sensors; Described eccentrically weighted shaft also can be provided with six or seven or nine or ten contiguous blocks.So, also all within scope, repeat no longer one by one here.
Claims (6)
1. an immune fully-automatic analyzer, it is characterized in that comprising housing, support body, be located at the sample area on support body, lath feed mechanism, buffer zone, hatch mechanism, four station mechanisms, testing agency and control system, described housing is covered in outside described support body, side, described sample area is provided with sample suction nozzle, sample application arm is provided with on the left of described support body, right side is provided with reagent pipetting volume arm, described mechanism of hatching is located at lath feed mechanism side, described buffer zone is located at described lath feed mechanism and is hatched between mechanism, described four station mechanisms are located at and are hatched mechanism front, described testing agency is located at hatches mechanism rear, reagent area is provided with below described four station mechanisms, described lath feed mechanism comprises the first pusher arms, described first pusher arms is provided with the first push rod, described four station mechanisms and hatch mechanism side and be provided with the second pusher arms by column, described second pusher arms moves up and down along column, described second pusher arms is provided with lath transfer handgrip, described lath transfer handgrip moves forward and backward along the second pusher arms, described lath transfer handgrip is provided with the second push rod, described second push rod moves left and right along lath transfer handgrip, reagent suction nozzle is provided with on the right side of described second pusher arms, described four station mechanisms comprise four work position rotation tables, turntable erecting bed, wash module and reagent adding module, described turntable erecting bed lower surface is provided with electric rotating machine, described four work position rotation tables are driven to rotate, described support body is provided with lifting motor, drive wash module moves up and down, described four work position rotation table upper surfaces are provided with the lath slot of four distributions in an angle of 90 degrees, described reagent adding module and wash module are located at above described four work position rotation tables side by side, described wash module is provided with a row and adds pin and a row and add the perpendicular suction spindle of pin, described reagent adding module comprises the first motor and reagent adding pin, described reagent adding pin is slidably connected by the first slide rail and the first slide block and described four work position rotation tables, described reagent adding pin is connected with described first motor by the first Timing Belt, described lath feed mechanism, hatch mechanism, testing agency, electric rotating machine, lifting motor and the first motor are electrically connected with described control system respectively, described immune fully-automatic analyzer also involving vibrations mechanism, described vibrating mechanism comprises holder, at least one vibrating motor, at least one diluted cup and at least one diluted cup mount pad, described vibrating motor is fixed on the lower surface of described holder, the output shaft of described vibrating motor passes described holder and exposes described holder upper surface, the output shaft of described vibrating motor is provided with an excentric shaft, the lower surface of described diluted cup mount pad is provided with a fixed block, the center of described fixed block is provided with a manhole, described excentric shaft is located in described manhole, described diluted cup is located on the upper surface of described diluted cup mount pad, four rubber blankets are provided with between the lower surface of described diluted cup mount pad and the upper surface of described holder, the lower end of described rubber blanket is fixed on described holder, the lateral surface of described holder is positioned at each diluted cup side and is respectively provided with a sensor, and the height of described sensor is higher than the height of described diluted cup mount pad, described lath feed mechanism comprises riser, base plate, lath, lath frame, storehouse and plate taking-out mechanism, and be provided with some laminate bar framves in described storehouse in the vertical, described lath frame is provided with some lath grooves, and described lath is located in described lath groove, one of them side of described base plate is provided with the first slide rail, the lower surface of described base plate is provided with the first motor, described first slide rail is provided with the first slide block, described first slide block and the first slide rail are slidably connected, described first slide block is connected with described first motor by the first Timing Belt, described first slide block is provided with the first pusher arms, described first pusher arms is provided with the first push rod, second motor and the second slide rail, described second slide rail is provided with the second slide block be slidably connected with it, and be connected with described second motor by the second Timing Belt, described first push rod is located on described second slide block, another side of described base plate is provided with the 3rd slide rail, the lower surface of described base plate is provided with the 3rd motor, described 3rd slide rail is provided with the 3rd slide block, described 3rd slide block and the 3rd slide rail are slidably connected, described 3rd slide block is connected with described 3rd motor by the 3rd Timing Belt, and described buffer zone is located on described 3rd slide block, described riser is provided with the 4th motor and two articles of the 4th slide rails be parallel to each other, article described two, be provided with the first screw mandrel between the 4th slide rail, described 4th motor is connected by the 4th Timing Belt one end with described first screw mandrel, described first screw mandrel is provided with Four-slider, described Four-slider and described 4th slide rail are slidably connected, and described base plate is fixed on described Four-slider, described column is provided with the 6th motor and two articles of the 6th slide rails be parallel to each other, article described two, be provided with the second screw mandrel between the 6th slide rail, described 6th motor is connected by the 6th Timing Belt one end with described second screw mandrel, described second screw mandrel is provided with the 6th slide block, described 6th slide block and described 6th slide rail are slidably connected, and described second pusher arms is fixed on described 6th slide block, described second pusher arms is provided with the 7th motor, and described lath transfer handgrip is connected with the 7th motor by the 7th Timing Belt, described lath transfer handgrip is provided with the 8th motor, and described second push rod is connected with the 8th motor by the 8th Timing Belt, described mechanism of hatching comprises shell, fixed head, vibration motor and lath frame, described fixed head is provided with two eccentrically weighted shafts arranged in parallel, described vibration motor drives described two eccentrically weighted shafts to rotate, described eccentrically weighted shaft is provided with some contiguous blocks, described lath is set up between two pieces of contiguous blocks on two eccentrically weighted shafts, described eccentrically weighted shaft rotates relative to contiguous block, described lath frame is driven to vibrate in the horizontal plane, the lower surface of described lath frame is provided with heating plate, it is outside that described shell is located at described lath frame, the front and back sides of described shell is by a rolling door sealing, described rolling door is provided with a transversal slotting, described fixed head is provided with rolling door motor, transversal slotting on described rolling door is moved up and down by rolling door motor, the lower surface of each lath frame is provided with temperature sensor.
2. immune fully-automatic analyzer as claimed in claim 1, it is characterized in that described plate taking-out mechanism comprises handgrip, the 5th motor, the 5th slide rail and the 5th slide block, described 5th motor is located on the lower surface of described base plate, described 5th slide rail is located on the upper surface of described base plate, described 5th slide block is located on described 5th slide rail, and be slidably connected with the 5th slide rail, described 5th motor is connected with described 5th slide block by the 5th Timing Belt.
3. immune fully-automatic analyzer as claimed in claim 2, it is characterized in that described buffer zone comprises lath frame and clamping piece, described lath frame comprises base and is located on base upper surface some blend stop arranged in parallel, the upper surface of described blend stop is provided with some jacks, opposite position place on the lower surface of described clamping piece is provided with some inserted links, described inserted link inserts in described jack, described base is provided with some through holes, described through hole is between two adjacent blend stops, the lower surface of described base is provided with a cooling piece, the width of described clamping piece is greater than the width of described blend stop, described lath is located between described two adjacent blend stops, and described two adjacent clamping pieces compress the both sides at described lath upper opening place respectively.
4. immune fully-automatic analyzer as claimed in claim 1, it is characterized in that the side of a described vibration motor eccentrically weighted shaft located therein, the first synchronizing wheel and the second synchronizing wheel is provided with near the lower end of the eccentrically weighted shaft of described vibration motor, the lower end of another root eccentrically weighted shaft is provided with the 3rd synchronizing wheel, the output terminal of described vibration motor is provided with the 4th synchronizing wheel, described 4th synchronizing wheel is connected with described first synchronizing wheel by the 9th Timing Belt, and described second synchronizing wheel is connected with described 3rd synchronizing wheel by the tenth Timing Belt.
5. immune fully-automatic analyzer as claimed in claim 4, it is characterized in that described fixed head is provided with lower rotary shaft, the lower end of described rolling door twists on described lower rotary shaft, the inside surface of described shell is provided with rotating shaft, the upper end of described rolling door twists in described upper rotating shaft, the output terminal of described rolling door motor is provided with the 5th synchronizing wheel, the two ends of described lower rotary shaft are respectively equipped with the 6th synchronizing wheel and the 7th synchronizing wheel, one end of described upper rotating shaft is provided with the 8th synchronizing wheel, described 5th synchronizing wheel is connected by the 11 Timing Belt with the 6th synchronizing wheel, described 7th synchronizing wheel is connected by the 12 Timing Belt with the 8th synchronizing wheel.
6. immune fully-automatic analyzer as claimed in claim 3, it is characterized in that in described reagent area, being provided with A liquid, B liquid and stop buffer, reaction reagent district is provided with on the right side of described reagent suction nozzle, the side of described sample area is provided with Article 1 ink recorder, in described storehouse, every laminate bar frame side is equipped with an Article 2 ink recorder, and described Article 1 ink recorder and Article 2 ink recorder are electrically connected with control system respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510653257.1A CN105319379B (en) | 2014-05-21 | 2014-05-21 | Full-automatic analyzer for immunity |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410248329.XA CN104215783B (en) | 2014-05-21 | 2014-05-21 | A kind of bar formula immunity fully-automatic analyzer |
| CN201510653257.1A CN105319379B (en) | 2014-05-21 | 2014-05-21 | Full-automatic analyzer for immunity |
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| CN201410248329.XA Division CN104215783B (en) | 2014-05-21 | 2014-05-21 | A kind of bar formula immunity fully-automatic analyzer |
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| CN105319379A true CN105319379A (en) | 2016-02-10 |
| CN105319379B CN105319379B (en) | 2017-02-22 |
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| CN201410248329.XA Active CN104215783B (en) | 2014-05-21 | 2014-05-21 | A kind of bar formula immunity fully-automatic analyzer |
| CN201510653343.2A Active CN105353158B (en) | 2014-05-21 | 2014-05-21 | Improved strip type automatic immunoassay analyzer |
| CN201510653257.1A Active CN105319379B (en) | 2014-05-21 | 2014-05-21 | Full-automatic analyzer for immunity |
| CN201510653220.9A Active CN105319378B (en) | 2014-05-21 | 2014-05-21 | Batten type fully-automatic immunity analyzer |
| CN201510653340.9A Active CN105242055B (en) | 2014-05-21 | 2014-05-21 | Improved bar formula immunity fully-automatic analyzer |
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| CN201510653343.2A Active CN105353158B (en) | 2014-05-21 | 2014-05-21 | Improved strip type automatic immunoassay analyzer |
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| CN201510653220.9A Active CN105319378B (en) | 2014-05-21 | 2014-05-21 | Batten type fully-automatic immunity analyzer |
| CN201510653340.9A Active CN105242055B (en) | 2014-05-21 | 2014-05-21 | Improved bar formula immunity fully-automatic analyzer |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN105242055A (en) | 2016-01-13 |
| CN105353158B (en) | 2017-02-22 |
| CN105242055B (en) | 2017-04-05 |
| CN105319378A (en) | 2016-02-10 |
| CN104215783B (en) | 2015-10-07 |
| CN105319379B (en) | 2017-02-22 |
| CN105319378B (en) | 2017-02-22 |
| CN104215783A (en) | 2014-12-17 |
| CN105353158A (en) | 2016-02-24 |
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Effective date of registration: 20231102 Address after: 3 / F, building 1, 2-3 / F, building 2, No. 3535 linggongtang Road, Nanhu District, Jiaxing City, Zhejiang Province, 314001 Patentee after: Jiaxing Kaishi Biotechnology Co.,Ltd. Address before: Room 1-1179, Building 4, Fengjing Shopping Mall, No. 9135 Zhufeng Road, Jinshan District, Shanghai, January 2015 Patentee before: KAIHE BIOTECHNOLOGY (SHANGHAI) Co.,Ltd. |
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