CN105319378B - Batten type fully-automatic immunity analyzer - Google Patents
Batten type fully-automatic immunity analyzer Download PDFInfo
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- CN105319378B CN105319378B CN201510653220.9A CN201510653220A CN105319378B CN 105319378 B CN105319378 B CN 105319378B CN 201510653220 A CN201510653220 A CN 201510653220A CN 105319378 B CN105319378 B CN 105319378B
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- lath
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- slide block
- reagent
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- 230000036039 immunity Effects 0.000 title claims abstract description 23
- 230000007246 mechanism Effects 0.000 claims abstract description 90
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 67
- 238000011534 incubation Methods 0.000 claims abstract description 32
- 238000005096 rolling process Methods 0.000 claims description 27
- 239000000203 mixture Substances 0.000 claims description 20
- 238000012546 transfer Methods 0.000 claims description 17
- 239000007788 liquid Substances 0.000 claims description 14
- 238000012360 testing method Methods 0.000 claims description 14
- 230000006835 compression Effects 0.000 claims description 13
- 238000007906 compression Methods 0.000 claims description 13
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 2
- 238000001514 detection method Methods 0.000 abstract description 13
- 238000011010 flushing procedure Methods 0.000 abstract 4
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000011004 medical lab test Methods 0.000 abstract 1
- 230000005611 electricity Effects 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 239000000376 reactant Substances 0.000 description 3
- 238000013475 authorization Methods 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000012790 confirmation Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000010355 oscillation Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002558 medical inspection Methods 0.000 description 1
- 230000008450 motivation Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention relates to the technical field of medical lab test equipment, in particular to a batten type fully-automatic immunity analyzer. The batten type fully-automatic immunity analyzer comprises a shell, a frame, a sample area arranged on the frame, a batten feeding mechanism, a buffer area, an incubation mechanism, a four-station mechanism, a detection mechanism and a control system, wherein the four-station mechanism comprises a four-station rotary table, a rotary table erecting bed, a flushing module and a reagent adding module, a rotary motor is arranged on the lower surface of the rotary table erecting bed to drive the four-station rotary table to rotate, a lifting motor is arranged on the frame to drive the flushing module to move up and down, four batten insertion grooves distributed in a 90-degree angle mode are formed in the upper surface of the four-station rotary table, the reagent adding module and the flushing module are arranged above the four-station rotary table side by side, a row of adding needles and a row of suction needles perpendicular to the adding needles are arranged on the flushing module, and the reagent adding module comprises a reagent adding motor and reagent adding needles.
Description
Technical field
The present invention relates to technical field of medical inspection equipment, specifically a kind of bar formula immunity fully-automatic analyzer.
Background technology
Existing immunity analysis instrument is generally used for reading 96 holes or 48 hole microwell plates at present, and so-called 96 holes or 48 holes are micro-
Orifice plate is 96 or 48 reaction cup of inclusion on plank, and each needs the sample of detection to be placed in a reaction cup, works as needs
The sample size of detection is only several or needs also exist for, using a monoblock 96 hole or 48 hole microwell plates, therefore making when more than ten
Become substantial amounts of waste, and the time needed for first hole of sample-adding is to last hole for the microwell plate in 96 holes or 48 holes is relatively
Long, therefore the concordance of result is had a certain impact, for example, Authorization Notice No. is disclosed in prior to 19 days March in 2014
The patent of CN203490229U, discloses a kind of standard board-like immunity analysis instrument automatically, mainly single by casing, placement unit, incubation
Unit, cleaning unit, substrate filling unit, optical detection unit and system operations control unit composition it is achieved that reactant liquor incubate,
Reactant liquor washes plate, reactant liquor from the whole process of note plus substrate measurement, can place two pieces of microwell plates during operation simultaneously.The opposing party
Face, on market, existing single reaction cup, as transmission, a detector unit, can also be examined when only one of which sample
Survey, but, the efficiency of this kind of single detection is not high enough, and when sample size is big, detection time is long, is not suitable for large quantities of
Amount inspection, for example, Authorization Notice No. is the patent of CN102183639B disclosed in prior to 5 days June in 2013, discloses one kind
Full-automatic chemiluminescence immunoassay analysis meter, by reaction cup feed system, three-dimensional mobile sample-adding module, sample area, reagent area, pump
Group, control system composition, are that single reaction cup carries out transmission detection.
Content of the invention
A kind of present invention structure of offer is simple, volume compact, bar formula easy and simple to handle immunity fully-automatic analyzer.
The present invention is achieved through the following technical solutions：
Bar formula immunity fully-automatic analyzer, including housing, support body, the sample area on support body, lath feed mechanism, delays
Rush area, incubation mechanism, four station mechanisms, testing agency and control system, described housing is covered in outside described support body, described sample
Local area side is provided with sample suction nozzle, is provided with sample application arm on the left of described support body, and right side is provided with reagent pipetting volume arm, described incubation machine
Structure and is incubated between mechanism, described four works located at described lath feed mechanism located at lath feed mechanism side, described relief area
In front of incubation mechanism, described testing agency, located at incubation mechanism rear, is provided with examination below described four station mechanisms for position mechanism
Agent area, described lath feed mechanism includes the first pusher arms, and described first pusher arms are provided with the first push rod, described four station machines
Structure and incubation mechanism side are provided with the second pusher arms by column, and described second pusher arms move up and down along column, and described second
Pusher arms are provided with lath transfer handgrip, and described lath transfer handgrip moves forward and backward along the second pusher arms, and described lath transfer is grabbed
It is provided with the second push rod on hand, described second push rod moves left and right along lath transfer handgrip, is provided with examination on the right side of described second pusher arms
Agent suction nozzle, described four station mechanisms include four work position rotation tables, turntable erecting bed, wash module and reagent adding module, described turntable
Erecting bed lower surface is provided with electric rotating machine, drives described four work position rotation tables to rotate, described support body is provided with lifting motor, drives
Wash module move up and down, described four work position rotation table upper surfaces be provided with four be in an angle of 90 degrees distribution lath slots, described plus
, side by side above described four work position rotation tables, described wash module is provided with a row and adds pin and a row for reagent modules and wash module
The suction spindle perpendicular with adding pin, described reagent adding module includes reagent adding motor and reagent adding pin, and described reagent adding pin passes through to add
Reagent slide rail and reagent adding slide block are slidably connected with described four work position rotation tables, and described reagent adding pin passes through reagent adding Timing Belt and institute
State reagent adding motor to be connected, described lath feed mechanism, incubation mechanism, testing agency, electric rotating machine, lifting motor and additional examination
Agent motor is electrically connected with described control system respectively；Described bar formula immunity fully-automatic analyzer also includes vibrating mechanism, described shakes
Motivation structure includes fixed seat, at least one vibrating motor, at least one diluted cup and at least one diluted cup mounting seat, described shakes
Galvanic electricity machine is fixed on the lower surface of described fixed seat, and the output shaft of described vibrating motor passes through described fixed seat and exposes described
Fixed seat upper surface, the output shaft of described vibrating motor is provided with an eccentric shaft, on the lower surface of described diluted cup mounting seat
It is provided with a fixed block, the center of described fixed block is provided with a manhole, and described eccentric shaft is located at described manhole
Interior, on the upper surface of described diluted cup mounting seat, the lower surface of described diluted cup mounting seat is solid with described for described diluted cup
It is provided with four rubber blankets, the lower end of described rubber blanket is fixed in described fixed seat, described fixed seat between the upper surface of reservation
Lateral surface be respectively provided with a sensor positioned at each diluted cup side, and the height of described sensor be higher than described diluted cup
The height of mounting seat；Described column is provided with the 6th motor and two articles of the 6th slide rails being parallel to each other, described two article of the 6th slide rail
Between be provided with the second screw mandrel, described 6th motor is connected with one end of described second screw mandrel by the 6th Timing Belt, described
Two screw mandrels are provided with the 6th slide block, and described 6th slide block and described 6th slide rail are slidably connected, and described second pusher arms are fixed on
On described 6th slide block；Described second pusher arms are provided with the 7th motor, described lath transfer handgrip pass through the 7th Timing Belt with
7th motor is connected；Described lath transfer handgrip is provided with the 8th motor, and described second push rod passes through the 8th Timing Belt and the
Eight motors are connected；Described incubation mechanism includes shell, fixed plate, vibration motor and lath frame, and described fixed plate is provided with two
Root eccentrically weighted shaft arranged in parallel, described vibration motor drives described two eccentrically weighted shafts to rotate, on described eccentrically weighted shaft
It is provided with some contiguous blocks, described lath is set up between two pieces of contiguous blocks on two eccentrically weighted shafts, described eccentrically weighted shaft is relatively
Contiguous block rotates, and drives described lath frame to vibrate in the horizontal plane, the lower surface of described lath frame is provided with heating plate, described outer
Outside described lath frame, the front and back sides of described shell pass through a rolling door sealing to shell, and described rolling door is provided with a horizontal stroke
To fluting, described fixed plate is provided with rolling door motor, and the transversal slotting on described rolling door is moved up and down by rolling door motor, each
The lower surface of lath frame is provided with temperature sensor.
Described lath feed mechanism includes riser, base plate, lath, lath frame, storehouse and plate taking-out mechanism, in described storehouse
Longitudinal direction is provided with some laminate bar framves, and described lath frame is provided with some batten bar grooves, and described lath is in described lath groove；
One of side of described base plate is provided with the first slide rail, and the lower surface of described base plate is provided with the first motor, and described first
Slide rail is provided with the first slide block, and described first slide block and the first slide rail are slidably connected, and described first slide block passes through the first Timing Belt
It is connected with described first motor, described first slide block is provided with the first pusher arms, described first pusher arms are provided with first and push away
Bar, the second motor and the second slide rail, described second slide rail is provided with the second slide block being slidably connected therewith, and synchronous by second
Band is connected with described second motor, and described first push rod is on described second slide block；On another side of described base plate
It is provided with the 3rd slide rail, the lower surface of described base plate is provided with the 3rd motor, and described 3rd slide rail is provided with the 3rd slide block, described
Three slide blocks are slidably connected with the 3rd slide rail, and described 3rd slide block is connected with described 3rd motor by the 3rd Timing Belt, described
Relief area is on described 3rd slide block；Described riser is provided with the 4th motor and two articles of the 4th slide rails being parallel to each other, described
Article two, it is provided with the first screw mandrel between the 4th slide rail, described 4th motor passes through one end phase of the 4th Timing Belt and described first screw mandrel
Connect, described first screw mandrel is provided with Four-slider, and described Four-slider is slidably connected with described 4th slide rail, described base plate is solid
On described Four-slider.
Described plate taking-out mechanism includes handgrip, the 5th motor, the 5th slide rail and the 5th slide block, and described 5th motor is located at described
On the lower surface of base plate, on the upper surface of described base plate, described 5th slide block is sliding located at the described 5th for described 5th slide rail
On rail, and it is slidably connected with the 5th slide rail, described 5th motor is connected with described 5th slide block by the 5th Timing Belt.
Described relief area includes lath frame and compression piece, if described lath frame includes base and on base upper surface
Dry bar blend stop arranged in parallel, the upper surface of described blend stop is provided with some jacks, on the lower surface of described compression piece
It is provided with some inserted links, described inserted link inserts in described jack, described base is provided with some through holes, described logical at opposite position
Between two adjacent blend stops, the lower surface of described base is provided with a cooling piece to hole position, and the width of described compression piece is more than institute
State the width of blend stop, described lath is between described two adjacent blend stops, and described two adjacent compression pieces are respectively
Compress the both sides at described lath upper opening.
Described vibration motor is located therein the side of an eccentrically weighted shaft, under the eccentrically weighted shaft of described vibration motor
End is provided with the first synchronizing wheel and the second synchronizing wheel, and the lower end of another eccentrically weighted shaft is provided with the 3rd synchronizing wheel, described vibration motor
Outfan be provided with the 4th synchronizing wheel, described 4th synchronizing wheel is connected with described first synchronizing wheel by the 9th Timing Belt, institute
State the second synchronizing wheel to be connected with described 3rd synchronizing wheel by the tenth Timing Belt.
Described fixed plate is provided with lower rotary shaft, and the lower end of described rolling door is rolled up on described lower rotary shaft, the interior table of described shell
Face is provided with rotating shaft, in the rotating shaft on described of the upper end volume of described rolling door, the outfan of described rolling door motor be provided with the 5th with
Step wheel, described lower rotary shaft be respectively arranged at two ends with the 6th synchronizing wheel and the 7th synchronizing wheel, one end of described upper rotating shaft is provided with the 8th
Synchronizing wheel, described 5th synchronizing wheel is connected by the 11st Timing Belt with the 6th synchronizing wheel, described 7th synchronizing wheel and the 8th
Synchronizing wheel is connected by the 12nd Timing Belt.
It is provided with A liquid, B liquid and terminate liquid in described reagent area, on the right side of described reagent suction nozzle, be provided with reaction reagent area, described sample
The side of local area is provided with the first barcode machine, and in described storehouse, every laminate bar frame side is equipped with second barcode machine, and described
One barcode machine and the second barcode machine are electrically connected with control system respectively.Place in described storehouse various for detecting different samples
Lath frame, which kind of sample the first barcode machine scanning confirmation is, and then determines adopted which kind of lath frame by the second barcode machine.
The beneficial effect that the present invention is brought is：
In the present invention, described bar formula immunity fully-automatic analyzer is supported not shutting down loading, and that is, user can be non-stop-machine
In the case of the continuous lath frame that will placed lath from storehouse add, then taken out by plate taking-out mechanism, and pass through at relief area
Sample application arm is loaded, and after sample-adding, lath moves into incubation mechanism and incubated and oscillation treatment, and lath is turned by lath afterwards
Move handgrip and the second push rod moves on to and carries out on four station mechanisms inhaling the operation of mix reagent adding, described lath moves into testing agency afterwards
Detected and the lath after having detected is discharged in pail for used dressings, above whole process can be under non-stop-machine state
It is carried out continuously, which improves detection efficiency, and ensure that the accuracy of detection；On the other hand, by 96 holes or 48 holes
Hole microwell plate resolve into single lath and enter detection, ratio is more flexible using the hole microwell plate detection in 96 holes or 48 holes, and
And it is cost-effective；When single lath enters flowing water detection, react to last from first reaction cup sample-adding or reagent adding
The time interval of cup sample-adding or reagent adding is short, and then testing result is more accurate；Relative, than single reaction cup detection efficiency
More increase, operative is easier.
Brief description
Below in conjunction with accompanying drawing, the present invention is described in further detail.
Fig. 1 is the structural representation of bar formula immunity fully-automatic analyzer of the present invention.
Fig. 2 is the structural representation that bar formula immunity fully-automatic analyzer of the present invention removes housing.
Fig. 3 is the structural representation in four station mechanism fronts of the present invention.
Fig. 4 is the structural representation of four station mechanism reverse side of the present invention.
Fig. 5 is the structural representation in vibrating mechanism front of the present invention.
Fig. 6 is the structural representation of vibrating mechanism reverse side of the present invention.
Fig. 7 is the structural representation in lath feed mechanism front of the present invention.
Fig. 8 is the structural representation of lath feed mechanism reverse side of the present invention.
Fig. 9 is the structural representation in relief area of the present invention front.
Figure 10 is the structural representation of relief area of the present invention reverse side.
Figure 11 is four station mechanisms of the present invention, is incubated the structural representation of mechanism and testing agency.
Figure 12 is the structural representation of incubation mechanism of the present invention.
Figure 13 is the structural representation that incubation mechanism of the present invention removes shell and rolling door.
Figure 14 is the structural representation that incubation mechanism of the present invention removes shell.
The corresponding label of in figure component names is as follows：
1st, housing；2nd, support body；3rd, sample area；4th, testing agency；5th, sample suction nozzle；6th, sample application arm；7th, reagent pipetting volume
Arm；8th, the first pusher arms；9th, the first push rod；10th, column；11st, the second pusher arms；12nd, lath transfer handgrip；13rd, the second push rod；
14th, reagent suction nozzle；15th, four work position rotation table；16th, turntable erecting bed；17th, wash module；18th, electric rotating machine；19th, lifting motor；
20th, lath slot；21st, add pin；22nd, suction spindle；23rd, reagent adding motor；24th, reagent adding pin；25th, reagent adding slide rail；26th, reagent adding
Slide block；27th, reagent adding Timing Belt；28th, fixed seat；29th, vibrating motor；30th, diluted cup mounting seat；31st, diluted cup；32nd, eccentric
Axle；33rd, fixed block；34th, manhole；35th, rubber blanket；36th, sensor；37th, riser；38th, base plate；39th, lath；40th, lath
Frame；41st, storehouse；42nd, lath groove；43rd, the first slide rail；44th, the first motor；45th, the first slide block；46th, the first Timing Belt；47th,
Two motors；48th, the second slide rail；49th, the second Timing Belt；50th, the 3rd slide rail；51st, the 3rd motor；52nd, the 3rd slide block；53rd, the 3rd
Timing Belt；54th, the 4th motor；55th, the 4th slide rail；56th, screw mandrel；57th, the 4th Timing Belt；58th, Four-slider；59th, handgrip；60、
5th motor；61st, the 5th slide rail；62nd, the 5th slide block；63rd, compress piece；64th, base；65th, blend stop；66th, jack；67th, inserted link；
68th, through hole；69th, cooling piece；70th, the 6th motor；71st, the 6th slide rail；72nd, the second screw mandrel；73rd, the 6th Timing Belt；74th, the 6th is sliding
Block；75th, the 7th motor；76th, the 7th Timing Belt；77th, the 8th motor；78th, the 8th Timing Belt；79th, shell；80th, fixed plate；81、
Vibrating motor；82nd, eccentrically weighted shaft；83rd, contiguous block；84th, heating plate；85th, rolling door；86th, transversal slotting；87th, rolling door motor；88、
Temperature sensor；89th, the first synchronizing wheel；90th, the second synchronizing wheel；91st, the 8th synchronizing wheel；92nd, the 4th synchronizing wheel；93rd, the 9th is same
Step band；94th, the tenth Timing Belt；95th, lower rotary shaft；96th, upper rotating shaft；97th, the 5th synchronizing wheel；98th, the 6th synchronizing wheel；99th, the 7th is same
Step wheel；100th, the 8th synchronizing wheel；101st, the 11st Timing Belt；102nd, the 12nd Timing Belt；103rd, A liquid；104th, B liquid；105th, eventually
Only liquid；106th, reaction reagent area；107th, the first barcode machine；108th, the second barcode machine；109th, pick and place lath station；110th, first wash
Plate station；111st, second wash plate station；112nd, add A/B liquid station.
Specific embodiment
Below in conjunction with the accompanying drawings and embodiment the present invention is described in further detail：
As bar formula of the present invention immunity fully-automatic analyzer embodiment, as shown in Figure 1, Figure 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6,
Shown in Fig. 7, Fig. 8, Fig. 9, Figure 10, Figure 11, Figure 12, Figure 13 and Figure 14, including housing 1, support body 2, the sample area on support body 2
3rd, lath feed mechanism, relief area, incubation mechanism, four station mechanisms, testing agency 4 and control system（In figure is not shown）, institute
State housing 1 and be covered in outside described support body 2, described sample area 3 side is provided with sample suction nozzle 5, is provided with sample on the left of described support body 2
Sample arm 6, right side is provided with reagent pipetting volume arm 7, described incubation mechanism located at lath feed mechanism side, described relief area 3 located at
Between described lath feed mechanism and incubation mechanism, in front of incubation mechanism, described testing agency 4 sets described four station mechanisms
In incubation mechanism rear, it is provided with reagent area below described four station mechanisms, described lath feed mechanism includes the first pusher arms 8,
Described first pusher arms 8 are provided with the first push rod 9, and described four station mechanisms and incubation mechanism side are provided with second by column 10
Pusher arms 11, described second pusher arms 11 move up and down along column, and described second pusher arms 11 are provided with lath transfer handgrip 12,
Described lath transfer handgrip 12 moves forward and backward along the second pusher arms 11, and described lath transfer handgrip 12 is provided with the second push rod 13,
Described second push rod 13 shifts handgrip 12 along lath and moves left and right, and is provided with reagent suction nozzle 14, institute on the right side of described second pusher arms 11
State four station mechanisms and include four work position rotation tables 15, turntable erecting bed 16, wash module 17 and reagent adding module, described turntable is installed
Platform 16 lower surface is provided with electric rotating machine 18, drives described four work position rotation tables 16 to rotate, described support body 2 is provided with lifting motor
19, drive wash module 17 to move up and down, it is in the lath that an angle of 90 degrees is distributed that described four work position rotation table 16 upper surface is provided with four
Slot 20, described reagent adding module and wash module 17 side by side above described four work position rotation tables 16, described wash module 17
It is provided with a row and adds pin 21 and the row suction spindle 22 perpendicular with adding pin, described reagent adding module includes reagent adding motor 23 and adds
Reagent pin 24, described reagent adding pin 24 is passed through reagent adding slide rail 25 and reagent adding slide block 26 and is slided even with described four work position rotation table 16
Connect, described reagent adding pin 24 is connected with described reagent adding motor 23 by reagent adding Timing Belt 27, described lath feed mechanism,
Incubation mechanism, testing agency 4, electric rotating machine 18, lifting motor 19 and reagent adding motor 23 are electrically connected with described control system respectively
Connect.
In the present embodiment, described bar formula immunity fully-automatic analyzer also includes vibrating mechanism, and described vibrating mechanism includes solid
Reservation 29, two diluted cups 31 of 28, two vibrating motors and two diluted cup mounting seats 30, described vibrating motor 29 is fixed on institute
State on the lower surface of fixed seat 28, the output shaft of described vibrating motor 29 passes through described fixed seat 28 and exposes described fixed seat 28
Upper surface, the output shaft of described vibrating motor 29 is provided with an eccentric shaft 32, on the lower surface of described diluted cup mounting seat 30
It is provided with a fixed block 33, the center of described fixed block 33 is provided with a manhole 34, described eccentric shaft 32 is located at described
In manhole 34, described diluted cup 31 on the upper surface of described diluted cup mounting seat 30, described diluted cup mounting seat 30
Lower surface and the upper surface of described fixed seat 28 between be provided with four rubber blankets 35, institute is fixed in the lower end of described rubber blanket 35
State in fixed seat 28, the lateral surface of described fixed seat 28 is respectively provided with a sensor 36 positioned at each diluted cup 31 side, and
The height of described sensor 36 is higher than the height of described diluted cup mounting seat 30.
In the present embodiment, described lath feed mechanism includes riser 37, base plate 38, lath 39, lath frame 40, storehouse 41 and
Plate taking-out mechanism, is provided with ten laminate bar framves 40 in the vertical in described storehouse 41, described lath frame 40 is provided with 12 batten bar grooves
42, described lath 39 is in described lath groove 42；One of side of described base plate 38 is provided with the first slide rail 43, described
The lower surface of base plate 38 is provided with the first motor 44, and described first slide rail 43 is provided with the first slide block 45, described first slide block 45
It is slidably connected with the first slide rail 43, described first slide block 45 is connected with described first motor 44 by the first Timing Belt 46, institute
State the first slide block 45 and be provided with the first pusher arms 8, described first pusher arms 8 are provided with the first push rod 9, the second motor 47 and second
Slide rail 48, described second slide rail 48 is provided with the second slide block being slidably connected therewith（In figure is not shown）, and synchronous by second
Band 49 is connected with described second motor 47, and described first push rod 9 is on described second slide block；Described base plate 38 another
Side is provided with the 3rd slide rail 50, and the lower surface of described base plate 38 is provided with the 3rd motor 51, and described 3rd slide rail 50 is provided with
3rd slide block 52, described 3rd slide block 52 is slidably connected with the 3rd slide rail 50, and described 3rd slide block 52 passes through the 3rd Timing Belt 53
It is connected with described 3rd motor 51, described relief area is on described 3rd slide block 52；Described riser 37 is provided with the 4th electricity
Machine 54 and two articles of the 4th slide rails 55 being parallel to each other, are provided with the first screw mandrel 56 between described two article of the 4th slide rail 55, and the described 4th
Motor 54 is connected with one end of described first screw mandrel 56 by the 4th Timing Belt 57, and it is sliding that described first screw mandrel 56 is provided with the 4th
Block 58, described Four-slider 58 is slidably connected with described 4th slide rail 55, and described base plate 38 is fixed on described Four-slider 58.
In the present embodiment, described plate taking-out mechanism includes handgrip 59, the 5th motor 60, the 5th slide rail 61 and the 5th slide block 62,
, on the lower surface of described base plate 38, described 5th slide rail 61 is located at the upper surface of described base plate 38 for described 5th motor 60
On, described 5th slide block 62 is on described 5th slide rail 61, and is slidably connected with the 5th slide rail 61, and described 5th motor 60 leads to
Cross the 5th Timing Belt（In figure is not shown）It is connected with described 5th slide block 62.
In the present embodiment, described relief area includes lath frame 40 and compression piece 63, and described lath frame 40 includes base 64 He
Six on base upper surface blend stops 65 arranged in parallel, the upper surface of described blend stop 65 is provided with three jacks
66, it is provided with three inserted links 67 at the opposite position on the lower surface of described compression piece 63, described inserted link 67 inserts described jack
In 66, described base 64 is provided with eight through holes 68, and described through hole 68 is located between two adjacent blend stops, the following table of described base 64
Face is provided with a cooling piece 69, and the width of described compression piece 63 is more than the width of described blend stop 65, and described lath 39 is located at institute
State between two adjacent blend stops 65, and described two adjacent compression pieces 63 compress at described lath 39 upper opening respectively
Both sides.
In the present embodiment, described column 10 is provided with the 6th motor 70 and two articles of the 6th slide rails 71 being parallel to each other, described
Article two, it is provided with the second screw mandrel 72 between the 6th slide rail 71, described 6th motor 70 passes through the 6th Timing Belt 73 and described second screw mandrel
72 one end is connected, and described second screw mandrel 72 is provided with the 6th slide block 74, described 6th slide block 74 and described 6th slide rail 71
It is slidably connected, described second pusher arms 11 are fixed on described 6th slide block 74；Described second pusher arms 11 are provided with the 7th electricity
Machine 75, described lath transfer handgrip 12 is connected with the 7th motor 75 by the 7th Timing Belt 76；Described lath shifts handgrip 12
It is provided with the 8th motor 77, described second push rod 13 is connected with the 8th motor 77 by the 8th Timing Belt 78.
In the present embodiment, described incubation mechanism includes shell 79, fixed plate 80, vibration motor 81 and lath frame 40, described
Fixed plate 80 is provided with two eccentrically weighted shafts 82 arranged in parallel, and described vibration motor 81 drives described two eccentrically weighted shafts
82 rotations, described eccentrically weighted shaft 82 is provided with eight contiguous blocks 83, described lath frame 40 on two eccentrically weighted shafts 82 two
Between block contiguous block 83, described eccentrically weighted shaft 82 rotates relative to contiguous block 83, drives described lath frame 40 to vibrate in the horizontal plane,
The lower surface of described lath frame 40 is provided with heating plate 84, described shell 79 outside described lath frame 40, described shell 79
Front and back sides sealed by a rolling door 85, described rolling door 85 is provided with a transversal slotting 86, and described fixed plate 80 sets
There is rolling door motor 87, the transversal slotting 86 on described rolling door 85 is moved up and down by rolling door motor 87, under each lath frame 40
Surface is provided with temperature sensor 88.
In the present embodiment, described vibration motor 81 is located therein the side of an eccentrically weighted shaft 82, near described vibration electricity
The lower end of the eccentrically weighted shaft 82 of machine 81 is provided with the first synchronizing wheel 89 and the second synchronizing wheel 90, and the lower end of another eccentrically weighted shaft 82 sets
There is the 3rd synchronizing wheel 91, the outfan of described vibration motor 81 is provided with the 4th synchronizing wheel 92, described 4th synchronizing wheel 92 passes through the
Nine Timing Belts 93 are connected with described first synchronizing wheel 89, and described second synchronizing wheel 90 passes through the tenth Timing Belt 94 and the described 3rd
Synchronizing wheel 91 is connected.
In the present embodiment, described fixed plate 80 is provided with lower rotary shaft 95, and the lower end of described rolling door 85 is rolled up in described lower rotary shaft
On 95, the inner surface of described shell 79 is provided with rotating shaft 96, in the rotating shaft 96 on described of the upper end volume of described rolling door 85, described
The outfan of rolling door motor 87 is provided with the 5th synchronizing wheel 97, described lower rotary shaft 95 be respectively arranged at two ends with the 6th synchronizing wheel 98 and
Seven synchronizing wheels 99, one end of described upper rotating shaft 95 is provided with the 8th synchronizing wheel 100, described 5th synchronizing wheel 97 and the 6th synchronizing wheel 98
It is connected by the 11st Timing Belt 101, described 7th synchronizing wheel 99 and the 8th synchronizing wheel 100 pass through the 12nd Timing Belt 102
It is connected.
In the present embodiment, in described reagent area, it is provided with A liquid 103, B liquid 104 and terminate liquid 105, described reagent suction nozzle 14 is right
Side is provided with reaction reagent area 106, and the side of described sample area 3 is provided with the first barcode machine 107, every laminate bar frame in described storehouse 41
40 sides are equipped with second barcode machine 108, described first barcode machine 107 and the second barcode machine 108 respectively with control system
Electrical connection.The various lath framves 40 for detecting different samples are placed, the first barcode machine 107 scanning confirmation is in described storehouse 41
Which kind of sample, and then determine adopted which kind of lath frame 40 by the second barcode machine 108.
Operation principle is as follows：
User puts into the lath frame 40 that placed lath 39 in storehouse 41, can continue through in the case of non-stop-machine
Plate taking-out mechanism takes out, and is loaded by sample application arm 6 at relief area, and after sample-adding, lath 39 immigration incubation mechanism carries out temperature
Educate and oscillation treatment, deliver to four by the second push rod 13 when lath 39 shifts handgrip 12 by lath after incubation mechanism takes out
Shift with lath in the corresponding lath slot 20 of handgrip 12 on work position rotation table 15, now for picking and placeing lath station 109, in rotation
Under the drive of motor 18, four work position rotation table 15 dextrorotation turn 90 degrees, and reaches first and washes plate station 110, now, puts into one again
Lath 39, then ratate 90 degrees, when first lath 39 reaches second and wash plate station 111, put into a lath 39, four stations again
Turntable 15 ratates 90 degrees again, when first lath 39 reaches and add A/B liquid station 112, places into a lath 39, four stations turn
Platform ratates 90 degrees again, and this moment, first lath 39 returns to and pick and place lath station 109, then shifts handgrip 12 from lath by lath
Take out in slot 20, be put in incubation mechanism or testing machine 4 structure, carry out next step operation.
Certainly, eight layers or Floor 12 or 14 laminate bar framves can also be provided with described storehouse in the vertical；Described
Eight or ten or 14 batten bar grooves can also be provided with lath frame；Can also be provided with described bumper bracket four or
Or eight lath dashpots being parallel to each other article six,；Can also arrange on described base four or five or eight or
Or 12 blend stops article ten,；Two or four or five jacks can also be arranged on the upper surface of described blend stop, relatively
Answer, described compression piece arranges two or four or five inserted links；Can also arrange on described base four or
Six or ten through holes of person；Described vibrating mechanism can also include three or four or five vibrating motors, three or
Four or five bases of person and three or four or five diluted cups, each motor respectively with a diluted cup mounting seat
It is connected, each diluted cup mounting seat is respectively equipped with a diluted cup, corresponding, including three or four or five
Sensor；Six or seven or nine or ten contiguous blocks can also be provided with described eccentrically weighted shaft.So, also all exist
Within the scope of the present invention, no longer repeat one by one here.
Claims (7)
1. formula immunity fully-automatic analyzer is it is characterised in that include housing, support body, the sample area on support body, lath enter
To mechanism, relief area, incubation mechanism, four station mechanisms, testing agency and control system, described housing be covered in described support body it
Outward, described sample area side is provided with sample suction nozzle, is provided with sample application arm on the left of described support body, and right side is provided with reagent pipetting volume arm,
Described incubation mechanism located at lath feed mechanism side, described relief area located at described lath feed mechanism and incubation mechanism it
Between, in front of incubation mechanism, described testing agency is located at incubation mechanism rear, described four station mechanisms for described four station mechanisms
Lower section is provided with reagent area, and described lath feed mechanism includes the first pusher arms, and described first pusher arms are provided with the first push rod, institute
State four station mechanisms and incubation mechanism side is provided with the second pusher arms by column, described second pusher arms move down along along column
Dynamic, described second pusher arms are provided with lath transfer handgrip, and described lath transfer handgrip moves forward and backward along the second pusher arms, described
Lath transfer handgrip is provided with the second push rod, and described second push rod moves left and right along lath transfer handgrip, described second pusher arms
Right side is provided with reagent suction nozzle, and described four station mechanisms include four work position rotation tables, turntable erecting bed, wash module and reagent adding mould
Block, described turntable erecting bed lower surface is provided with electric rotating machine, drives described four work position rotation tables to rotate, described support body is provided with liter
Fall motor, drives wash module to move up and down, and it is in the lath that an angle of 90 degrees is distributed that described four work position rotation table upper surfaces are provided with four
, side by side above described four work position rotation tables, described wash module is provided with one for slot, described reagent adding module and wash module
Row plus pin and a row with plus the perpendicular suction spindle of pin, described reagent adding module includes reagent adding motor and reagent adding pin, described adds
Reagent pin is slidably connected with described four work position rotation tables by reagent adding slide rail and reagent adding slide block, and described reagent adding pin passes through additional examination
Agent Timing Belt is connected with described reagent adding motor, described lath feed mechanism, incubation mechanism, testing agency, electric rotating machine, liter
Fall motor and reagent adding motor are electrically connected with described control system respectively；Described bar formula immunity fully-automatic analyzer also includes vibrating
Mechanism, described vibrating mechanism includes fixed seat, at least one vibrating motor, at least one diluted cup and at least one diluted cup peace
Dress seat, described vibrating motor is fixed on the lower surface of described fixed seat, and the output shaft of described vibrating motor passes through described fixation
Seat simultaneously exposes described fixed seat upper surface, and the output shaft of described vibrating motor is provided with an eccentric shaft, and described diluted cup is installed
Seat lower surface be provided with a fixed block, the center of described fixed block is provided with a manhole, described eccentric shaft located at
In described manhole, described diluted cup on the upper surface of described diluted cup mounting seat, under described diluted cup mounting seat
It is provided with four rubber blankets, described fixed seat is fixed in the lower end of described rubber blanket between the upper surface of surface and described fixed seat
On, the lateral surface of described fixed seat is respectively provided with a sensor positioned at each diluted cup side, and the height of described sensor
Height higher than described diluted cup mounting seat；Described column is provided with the 6th motor and two articles of the 6th slide rails being parallel to each other, institute
State and between two article of the 6th slide rail, be provided with the second screw mandrel, described 6th motor passes through one end of the 6th Timing Belt and described second screw mandrel
It is connected, described second screw mandrel is provided with the 6th slide block, described 6th slide block and described 6th slide rail are slidably connected, described second
Pusher arms are fixed on described 6th slide block；Described second pusher arms are provided with the 7th motor, and described lath transfer handgrip passes through
7th Timing Belt is connected with the 7th motor；Described lath transfer handgrip is provided with the 8th motor, and described second push rod passes through the
Eight Timing Belts are connected with the 8th motor；Described incubation mechanism includes shell, fixed plate, vibration motor and lath frame, described solid
Fixed board is provided with two eccentrically weighted shafts arranged in parallel, and described vibration motor drives described two eccentrically weighted shafts to rotate, institute
State eccentrically weighted shaft and be provided with some contiguous blocks, described lath is set up between two pieces of contiguous blocks on two eccentrically weighted shafts, described
Eccentrically weighted shaft rotates relative to contiguous block, drives described lath frame to vibrate in the horizontal plane, the lower surface of described lath frame is provided with
Heating plate, outside described lath frame, the front and back sides of described shell pass through a rolling door sealing, described rolling door to described shell
It is provided with a transversal slotting, described fixed plate is provided with rolling door motor, the transversal slotting on described rolling door passes through rolling door motor
Move up and down, the lower surface of each lath frame is provided with temperature sensor.
2. bar formula immunity fully-automatic analyzer as claimed in claim 1 is it is characterised in that described lath feed mechanism includes standing
Plate, base plate, lath, lath frame, storehouse and plate taking-out mechanism, are provided with some laminate bar framves, described plate in the vertical in described storehouse
Bar frame is provided with some batten bar grooves, and described lath is in described lath groove；One of side of described base plate is provided with
First slide rail, the lower surface of described base plate is provided with the first motor, and described first slide rail is provided with the first slide block, and described first is sliding
Block is slidably connected with the first slide rail, and described first slide block is connected with described first motor by the first Timing Belt, and described first
Slide block is provided with the first pusher arms, and described first pusher arms are provided with the first push rod, the second motor and the second slide rail, and described second
Slide rail is provided with the second slide block being slidably connected therewith, and is connected with described second motor by the second Timing Belt, and described
One push rod is on described second slide block；Another side of described base plate is provided with the 3rd slide rail, the lower surface of described base plate
It is provided with the 3rd motor, described 3rd slide rail is provided with the 3rd slide block, and described 3rd slide block is slidably connected with the 3rd slide rail, described
3rd slide block is connected with described 3rd motor by the 3rd Timing Belt, and described relief area is on described 3rd slide block；Described
Riser is provided with the 4th motor and two articles of the 4th slide rails being parallel to each other, and is provided with the first screw mandrel between described two article of the 4th slide rail,
Described 4th motor is connected with one end of described first screw mandrel by the 4th Timing Belt, and it is sliding that described first screw mandrel is provided with the 4th
Block, described Four-slider is slidably connected with described 4th slide rail, and described base plate is fixed on described Four-slider.
3. as claimed in claim 2 article of formula immunity fully-automatic analyzer it is characterised in that described plate taking-out mechanism include handgrip, the
Five motors, the 5th slide rail and the 5th slide block, described 5th motor on the lower surface of described base plate, described 5th slide rail located at
On the upper surface of described base plate, described 5th slide block is on described 5th slide rail, and is slidably connected with the 5th slide rail, and described
Five motors are connected with described 5th slide block by the 5th Timing Belt.
4. bar formula as claimed in claim 3 immunity fully-automatic analyzer it is characterised in that described relief area include lath frame and
Compression piece, described lath frame includes base and some blend stops arranged in parallel on base upper surface, described gear
The upper surface of bar is provided with some jacks, is provided with some inserted links at the opposite position on the lower surface of described compression piece, described
Inserted link inserts in described jack, and described base is provided with some through holes, and described through hole is located between two adjacent blend stops, described base
Lower surface be provided with a cooling piece, the width of described compression piece is more than the width of described blend stop, and described lath is located at described
Article two, between adjacent blend stop, and described two adjacent compression pieces compress the both sides at described lath upper opening respectively.
5. bar formula immunity fully-automatic analyzer as claimed in claim 1 is it is characterised in that described vibration motor is located therein one
The side of root eccentrically weighted shaft, the lower end near the eccentrically weighted shaft of described vibration motor is provided with the first synchronizing wheel and the second synchronizing wheel,
The lower end of another eccentrically weighted shaft is provided with the 3rd synchronizing wheel, and the outfan of described vibration motor is provided with the 4th synchronizing wheel, and described
Four synchronizing wheels are connected with described first synchronizing wheel by the 9th Timing Belt, and described second synchronizing wheel passes through the tenth Timing Belt and institute
State the 3rd synchronizing wheel to be connected.
6. bar formula as claimed in claim 5 immunity fully-automatic analyzer is it is characterised in that described fixed plate is provided with lower rotary shaft,
The lower end of described rolling door is rolled up on described lower rotary shaft, and the inner surface of described shell is provided with rotating shaft, the upper end volume of described rolling door
In rotating shaft on described, the outfan of described rolling door motor is provided with the 5th synchronizing wheel, described lower rotary shaft be respectively arranged at two ends with
Six synchronizing wheels and the 7th synchronizing wheel, one end of described upper rotating shaft is provided with the 8th synchronizing wheel, described 5th synchronizing wheel and the 6th synchronization
Wheel is connected by the 11st Timing Belt, and described 7th synchronizing wheel is connected by the 12nd Timing Belt with the 8th synchronizing wheel.
7. bar formula immunity fully-automatic analyzer as claimed in claim 3 is it is characterised in that be provided with A liquid, B liquid in described reagent area
And terminate liquid, it is provided with reaction reagent area on the right side of described reagent suction nozzle, the side of described sample area is provided with the first barcode machine, described heap
In stack, every laminate bar frame side is equipped with second barcode machine, and described first barcode machine and the second barcode machine with controlling are respectively
System electrical connection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510653220.9A CN105319378B (en) | 2014-05-21 | 2014-05-21 | Batten type fully-automatic immunity analyzer |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510653220.9A CN105319378B (en) | 2014-05-21 | 2014-05-21 | Batten type fully-automatic immunity analyzer |
| CN201410248329.XA CN104215783B (en) | 2014-05-21 | 2014-05-21 | A kind of bar formula immunity fully-automatic analyzer |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410248329.XA Division CN104215783B (en) | 2014-05-21 | 2014-05-21 | A kind of bar formula immunity fully-automatic analyzer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105319378A CN105319378A (en) | 2016-02-10 |
| CN105319378B true CN105319378B (en) | 2017-02-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510653220.9A Active CN105319378B (en) | 2014-05-21 | 2014-05-21 | Batten type fully-automatic immunity analyzer |
| CN201510653343.2A Active CN105353158B (en) | 2014-05-21 | 2014-05-21 | Improved strip type automatic immunoassay analyzer |
| CN201410248329.XA Active CN104215783B (en) | 2014-05-21 | 2014-05-21 | A kind of bar formula immunity fully-automatic analyzer |
| CN201510653340.9A Active CN105242055B (en) | 2014-05-21 | 2014-05-21 | Improved bar formula immunity fully-automatic analyzer |
| CN201510653257.1A Active CN105319379B (en) | 2014-05-21 | 2014-05-21 | Full-automatic analyzer for immunity |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
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| CN201510653343.2A Active CN105353158B (en) | 2014-05-21 | 2014-05-21 | Improved strip type automatic immunoassay analyzer |
| CN201410248329.XA Active CN104215783B (en) | 2014-05-21 | 2014-05-21 | A kind of bar formula immunity fully-automatic analyzer |
| CN201510653340.9A Active CN105242055B (en) | 2014-05-21 | 2014-05-21 | Improved bar formula immunity fully-automatic analyzer |
| CN201510653257.1A Active CN105319379B (en) | 2014-05-21 | 2014-05-21 | Full-automatic analyzer for immunity |
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| CN105319378B (en) * | 2014-05-21 | 2017-02-22 | 凯和生物科技(上海)有限公司 | Batten type fully-automatic immunity analyzer |
| EP3312614B1 (en) | 2015-06-22 | 2024-11-13 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Sample analyzer |
| CN105092871A (en) * | 2015-08-10 | 2015-11-25 | 胥凤山 | Biochemical analyzer |
| CN105628947B (en) * | 2016-02-02 | 2017-08-08 | 徐恩良 | Whole blood automatic luminous immunoassay instant detector |
| CN106179541B (en) * | 2016-04-08 | 2018-10-30 | 深圳雷杜生命科学股份有限公司 | Biochip hybridization machine |
| CN105838582B (en) * | 2016-05-24 | 2018-10-23 | 江门市凯林贸易有限公司 | It is a kind of to divide sample component for mycoplasma identification and the automatic of Analysis of Drug Susceptibility |
| CN106018785B (en) * | 2016-06-30 | 2017-12-01 | 杭州凯坤科技有限公司 | A kind of reaction tray and full-automatic illumination immunity analysis instrument |
| CN106980024A (en) * | 2017-03-28 | 2017-07-25 | 杭州凯坤科技有限公司 | A kind of full-automatic light-induced chemiluminescent detector |
| CN107167584B (en) * | 2017-05-27 | 2020-03-03 | 北京热景生物技术股份有限公司 | Chemiluminescence immunity analyzer |
| CN110118876A (en) * | 2018-02-06 | 2019-08-13 | 北京科美生物技术有限公司 | A kind of multiple batches of operation method |
| CN108828246A (en) * | 2018-03-14 | 2018-11-16 | 嘉兴科瑞迪医疗器械有限公司 | A kind of reaction cup incubating device with manipulator |
| CN112166328A (en) | 2018-06-28 | 2021-01-01 | 深圳迈瑞生物医疗电子股份有限公司 | Continuous sample introduction method, sample introduction device and storage medium |
| CN108732364B (en) * | 2018-07-13 | 2024-08-06 | 深圳市活水床旁诊断仪器有限公司 | Incubation groove device |
| CN109541245B (en) * | 2018-12-06 | 2023-11-28 | 桂林优利特医疗电子有限公司 | Full-automatic test tube sample preprocessing device |
| CN109613291A (en) * | 2018-12-27 | 2019-04-12 | 天津博硕科技有限公司 | A kind of test strips export mechanism |
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| CN111299278B (en) * | 2019-11-21 | 2021-03-02 | 博奥赛斯（天津）生物科技有限公司 | Magnetic particle cleaning device |
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Also Published As
| Publication number | Publication date |
|---|---|
| CN105319379A (en) | 2016-02-10 |
| CN105242055A (en) | 2016-01-13 |
| CN104215783A (en) | 2014-12-17 |
| CN104215783B (en) | 2015-10-07 |
| CN105353158A (en) | 2016-02-24 |
| CN105353158B (en) | 2017-02-22 |
| CN105319378A (en) | 2016-02-10 |
| CN105319379B (en) | 2017-02-22 |
| CN105242055B (en) | 2017-04-05 |
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