CN105055223A - Traditional Chinese medicine toothpaste capable of stopping bleeding and desensitizing - Google Patents
Traditional Chinese medicine toothpaste capable of stopping bleeding and desensitizing Download PDFInfo
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- CN105055223A CN105055223A CN201510482617.6A CN201510482617A CN105055223A CN 105055223 A CN105055223 A CN 105055223A CN 201510482617 A CN201510482617 A CN 201510482617A CN 105055223 A CN105055223 A CN 105055223A
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Abstract
The invention discloses a traditional Chinese medicine toothpaste capable of stopping bleeding and desensitizing. 100g of a toothpaste base material of the traditional Chinese medicine toothpaste comprises 0.01 to 10% of pseudo-ginseng and 1.35% of an anti-sensitivity ingredient. 0.01 to 20% of a traditional Chinese medicine ingredient is also added into the traditional Chinese medicine toothpaste; the traditional Chinese medicine ingredient is one or a mixture of a plurality of components selected from Callicarpa pedunculata R. Brown, herba agrimoniae, and rhizoma bletillae; the traditional Chinese medicine ingredient is obtained via extraction of medicinal plants; and adding amounts of Callicarpa pedunculata R. Brown, herba agrimoniae, and rhizoma bletillae all range from 0.01 to 10.0%. The traditional Chinese medicine ingredients capable of cooling blood and stopping bleeding, and the anti-sensitivity ingredient are added into common toothpaste, so that the obtained traditional Chinese medicine toothpaste is capable of clearing heat and detoxifying, stopping bleeding and astringing, relieving swelling and pain, and desensitizing, and possesses excellent prevention and curative effects on common gingiva red and swollen, gingival bleeding, dental ulcer, and gingivitis.
Description
Technical field
The present invention relates to oral care product technical field, particularly relate to a kind of Chinese medicinal toothpaste with hemostasis antiallergic sense effect.
Background technology
Gingival hemorrhage is one of department of stomatology common sympton, and what refer to that gingiva is idiopathic or cause due to outside minimal irritation bleeds on a small quantity.The lighter show as only sucking, brush teeth, when chewing harder food in saliva with the blood streak, severe one is when gingiva is subject to minimal irritation and hemorrhage more even hematostaxis.Gingival hemorrhage have impact on daily life greatly, thereby produces the consumption demand for gingival hemorrhage.
China's natural resources of Chinese medicinal materials enriches, and the Chinese medicine ingredients with hemostasia effect is a lot, and Chinese medicinal toothpaste is more and more subject to consumers welcomed, therefore, develops a kind of Chinese medicinal toothpaste with alleviation gingival hemorrhage symptom and has certain market value.
The method of current treatment gingival hemorrhage generally adopts oral vitamin C, or uses dental care product.These methods are all cured the symptoms, not the disease, and cannot reach in daily life the object alleviating gingival hemorrhage.At present, not yet find the tooth paste product used in daily life, have good prevention and alleviate gingival hemorrhage, red swelling of gingiva technique effect.
Summary of the invention
In order to overcome the deficiencies in the prior art, the Chinese medicinal toothpaste with hemostasis antiallergic sense effect the object of the present invention is to provide a kind of good effect, having no side effect.
Active ingredient of Chinese herbs is introduced:
Radix Notoginseng: the rhizome goods of plant Radix Notoginseng (formal name used at school: Panaxpseudo-ginseng), are the powder broken into Radix Notoginseng main root, are
yUNNAN BAIYAOmain component.Another name: Radix Notoginseng powder, Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae).Originate from Yunnan mountain of papers, have title Radix Ginseng, southern Radix Notoginseng.Ginseng qi-tonifying the first, Radix Notoginseng enriches blood first.All the time, Radix Notoginseng is all extraordinary Chinese crude drug simply.General when wound doctor can advise eating Radix Notoginseng pot chicken, Be very effective of curing the wound.Main product ground is in the Yunnan of China and remote mountains, Guangxi, and warm in nature, sweet and slightly bitter taste, enters liver, stomach, large intestine channel.The function of Radix Notoginseng, available " hemostasis, dissipating blood stasis, analgesic therapy " six words were summarized originally, so, be always using Radix Notoginseng as traumatology Incised wound medicine, seldom eat as tonic.
Pseudobulbus Bletillae (Rhizoma Bletillae): the dry tuber of orchid Pseudobulbus Bletillae (Rhizoma Bletillae), has another name called sweet, the Pseudobulbus Bletillae (Rhizoma Bletillae) etc.Its bitter in the mouth, sweet, puckery, cold nature, has effect of astringing to arrest bleeding, detumescence and promoting granulation.Containing Bletilla glucomannan (for baregin) and volatile oil, for spitting of blood, spit blood, traumatic hemorrhage, sore swollen toxin, chapped skin.
Herba Agrimoniae: be the herb of rosaceous plant Agrimony, nature and flavor are pained and put down, containing Herba Agrimoniae (for phenol resin acid), Herba Agrimoniae A prime, Herba Agrimoniae B prime, Herba Agrimoniae C prime.Another containing tannin, vitamin K1 etc." modern Practical Chinese medicinal " is discussed it and " is the agent of robustness astringing to arrest bleeding, has cardiotonic concurrently.Be applicable to pneumonopathy spitting of blood, enterorrhagia, gastric hemorrhage, metrorrhagia, gear division is hemorrhage, hemorrhoidal bleeding, the diseases such as liver abscess." hemostasis of Herba Agrimoniae function, effect extensively, can be used for health each part hemorrhagic conditions, and no matter cold, heat, empty, real person all can apply.
Folium Callicarpae Formosanae: also known as Folium Callicarpae Formosanae or Folium Callicarpae Formosanae is Verenaceae Callicarpa plant callicarpa pedunculata, the leaf of Callicarpa dichotoma, stem, root.Folium Callicarpae Formosanae bitter in the mouth, puckery, mild in medicine property, bitter, cold.There is the function of cooling blood for hemostasis, dissipating blood stasis, antiinflammatory.Folium Callicarpae Formosanae has good anastalsis, can be used for multiple bleeding, also can be used for the disease such as sore and toxic, venom.
The object of the invention is to be achieved through the following technical solutions:
Have the Chinese medicinal toothpaste of hemostasis antiallergic sense effect, containing the Chinese medicine ingredients of 0.01% ~ 20% and the anti-sensitive composition of 1.35% in every 100g toothpaste matrix, its Chinese medicine ingredients is the mixing of in Radix Notoginseng, Folium Callicarpae Formosanae, Herba Agrimoniae, the Pseudobulbus Bletillae (Rhizoma Bletillae) two kinds or more; It can be the mixing of three kinds or four kinds; All the other are base ingredients, antiseptic, essence, pigment, water.
The present invention is containing the Chinese medicine hemostasis toothpaste of Radix Notoginseng, and described anti-sensitive composition is the mixing according to weight ratio 1:2 of strontium chloride and potassium nitrate.
The present invention, containing the Chinese medicine hemostasis toothpaste of Radix Notoginseng, contains 0.01% ~ 10% Radix Notoginseng composition in every 100g toothpaste matrix; Wherein Folium Callicarpae Formosanae, Herba Agrimoniae, Pseudobulbus Bletillae (Rhizoma Bletillae) addition are respectively 0.01% ~ 10.0%; When described Chinese medicine ingredients is applied in toothpaste, total addition level controls within 20.0% of toothpaste total amount.
The present invention is containing the Chinese medicine hemostasis toothpaste of Radix Notoginseng, described Chinese medicine ingredients is that medicinal plants extracts the bioactive ingredients obtained, the percentage by weight of described Chinese medicine ingredients and base ingredient is: Chinese medicine ingredients 0.1% ~ 20%, anti-sensitive composition 1.35%, grinding agent 15% ~ 55%, wetting agent 15% ~ 50%, adhesion agent 0.4% ~ 2%, foaming agent 0.5% ~ 4%, sweeting agent 0.05% ~ 0.3%, other compositions 0.01% ~ 10%.
The present invention has the Chinese medicinal toothpaste of hemostasis antiallergic sense effect, comprises each raw material components of following percentage by weight:
Radix Notoginseng extract 0.01 ~ 10.0%;
Pseudobulbus Bletillae (Rhizoma Bletillae) extract 0.01 ~ 10.0%;
Herba Agrimoniae extract 0.1 ~ 5.0%;
Folium Callicarpae Formosanae extract 0.1 ~ 5.0%;
Strontium chloride 0.45%;
Potassium nitrate 0.9%;
Grinding agent 15% ~ 55%;
Wetting agent 15% ~ 50%;
Adhesion agent 0.4% ~ 2%;
Foaming agent 0.5% ~ 4%;
Sweeting agent 0.05% ~ 0.3%;
Antiseptic 0.01% ~ 0.8%;
Essence 0.5% ~ 2%;
Water surplus.
The present invention is containing the Chinese medicine hemostasis toothpaste of Radix Notoginseng, and described grinding agent is the mixture of one or more in hydrated silica, calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, aluminium hydroxide, microcrystalline Cellulose; Described wetting agent is the mixture of one or more in sorbitol, glycerol, Polyethylene Glycol, propylene glycol; Described adhesion agent is the mixture of one or more of cellulose gum, carrageenan, xanthan gum, guar gum; Described foaming agent is one in laurilsulfate sodium, sodium lauroyl sarcosine, cocamido propyl betaine or its mixture; Described sweeting agent is one in saccharin sodium, sucralose, aspartame or its mixture, and other compositions described are antiseptic, essence, water.
The present invention, containing the Chinese medicine hemostasis toothpaste of Radix Notoginseng, also can add other both effectiveness raw materials in its formula, as mothproof composition polyvinylpyrrolidone or sodium fluoride etc.
Advantage of the present invention and good effect are:
1, plurality of Chinese cooling blood for hemostasis composition and anti-sensitive composition add in toothpaste by the present invention first jointly, and with in other Chinese medicine ingredients Folium Callicarpae Formosanae, Herba Agrimoniae, the Pseudobulbus Bletillae (Rhizoma Bletillae) multiple with the use of, by clinical trial certificate, it is alleviated gingival hemorrhage successful and strengthens.
2, Chinese medicinal toothpaste of the present invention has the effect alleviating gingival hemorrhage, red swelling of gingiva, aphtha, and instant effect, has no side effect, and has both been adapted at using when there is gingival hemorrhage symptom, is also applicable to prevention in daily life and uses.
3, in the present invention embodiment all for the extracting solution of Radix Notoginseng, Folium Callicarpae Formosanae, Herba Agrimoniae, the Pseudobulbus Bletillae (Rhizoma Bletillae), but be not limited to extracting solution or extractum etc.When being applied to oral care product in the mode of other forms as extract powder, its addition in formula suitably can be converted according to active component content.
4, the embodiment of the present invention all will be far longer than with the hemostasia effect of its formula of extracting solution of Radix Notoginseng, Folium Callicarpae Formosanae, Herba Agrimoniae, the Pseudobulbus Bletillae (Rhizoma Bletillae) effect being used alone one of them Chinese medicine.
Detailed description of the invention
Containing a Chinese medicine hemostasis toothpaste for Radix Notoginseng, containing 0.01% ~ 10% Radix Notoginseng composition in every 100g toothpaste matrix.Described Chinese medicine hemostasis toothpaste also adds the anti-sensitive composition of 0.01% ~ 20% Chinese medicine ingredients and 1.35%, and its Chinese medicine ingredients is one or more the mixing in Folium Callicarpae Formosanae, Herba Agrimoniae, the Pseudobulbus Bletillae (Rhizoma Bletillae); All the other are base ingredients, antiseptic, pigment, water.
The present invention, containing the Chinese medicine hemostasis toothpaste of Radix Notoginseng, contains 0.01% ~ 10% Radix Notoginseng composition in every 100g toothpaste matrix.The percentage by weight of described Chinese medicine ingredients and base ingredient is: Chinese medicine ingredients 0.1% ~ 20%, anti-sensitive composition 1.35%, grinding agent 15% ~ 55%, wetting agent 15% ~ 50%, adhesion agent 0.4% ~ 2%, foaming agent 0.5% ~ 4%, sweeting agent 0.05% ~ 0.3%, other compositions 0.01% ~ 10%.
Described grinding agent can be hydrated silica, calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, aluminium hydroxide or microcrystalline Cellulose etc.; Wetting agent can be the mixture of one or more in sorbitol, glycerol, propylene glycol, Polyethylene Glycol; Foaming agent is one in laurilsulfate sodium or potassium salt, cocamido propyl betaine, sodium lauroyl sarcosine or potassium or its mixture, or is that non-ionic surface active agent is as tween, lauryl alcohol diethanolamine, polyoxyethylene and polyoxypropylene block copolymers etc.; Described adhesion agent is the mixture of one or more of cellulose gum, carrageenan, xanthan gum, guar gum; Described sweeting agent is one in saccharin sodium, stevioside, sucralose or its mixture.
Below by way of concrete preferred embodiment, the present invention is expressed in further detail, but the present invention is not limited in following embodiment.
embodiment 1
Containing a Chinese medicine hemostasis toothpaste for Radix Notoginseng, the mass percent of its each constituent is: Radix Notoginseng extract 2.0%, Folium Callicarpae Formosanae extract 5.0%, bletilla striata extract 4.0%, strontium chloride 0.45%; Potassium nitrate 0.9%, calcium carbonate 38.0%, silicon dioxide 5.0%, sorbitol 20.0%, glycerol 5.0%, Polyethylene Glycol 2.0%, cellulose gum 0.5%, xanthan gum is 0.3%, laurilsulfate sodium 2.0%, cocamido propyl betaine 0.5%, essence 1.2%, sucralose 0.2%, surplus is pigment, antiseptic, water.
Processing technology for above-described embodiment is:
1) load weighted Radix Notoginseng extract, Folium Callicarpae Formosanae extract, bletilla striata extract, sweeting agent and other solid small powders etc. are dropped in premixing tank, stir and make material fully dissolve in rear suction Manufacturing medicine extract machine, start agitator and stir 2 ~ 3 minutes;
2) liquid materials such as appropriate sorbitol, glycerol, Polyethylene Glycol are sucked in Manufacturing medicine extract machine, start agitator and stir;
3) silicon dioxide of cellulose gum, xanthan gum, half amount is dropped into filler bin together with calcium carbonate, and stir 5 ~ 10 minutes, make it to mix in powder storehouse; Suck in Manufacturing medicine extract machine by material in powder storehouse again, homogenizing stirs 20 ~ 30 minutes;
4) balancing silicon dioxide and laurilsulfate sodium are added in Manufacturing medicine extract machine, under vacuum conditions rapid stirring 15 minutes;
5) essence measured, CAB are added in Manufacturing medicine extract machine, open vacuum stirring 10 ~ 15 minutes; Namely mastic is obtained.
Other both effectiveness raw materials also can be added, if anti-sensitivity, mothproof composition are as potassium nitrate, polyvinylpyrrolidone, sodium fluoride etc. in formula.
Herba Agrimoniae extract is not added in the present embodiment.
embodiment 2
Containing a Chinese medicine hemostasis toothpaste for Radix Notoginseng, its each constituent mass percent is: Radix Notoginseng extract 4.0%, Herba Agrimoniae extract 3.0%, bletilla striata extract 1.0%, strontium chloride 0.45%; Potassium nitrate 0.9%, silicon dioxide 23.0%, sorbitol 35.0%, glycerol 8.0%, Polyethylene Glycol 2.0%, cellulose gum 0.5%, carrageenan is 0.3%, laurilsulfate sodium 2.2%, cocamido propyl betaine 0.3%, essence 1.2%, saccharin sodium 0.15%, surplus is pigment, antiseptic, water.
The processing technology of above-described embodiment 2 is identical with embodiment 1, does not add Folium Callicarpae Formosanae extract in the present embodiment.
embodiment 3
Containing a Chinese medicine hemostasis toothpaste for Radix Notoginseng, its each constituent mass percent is: Radix Notoginseng extract 3.0%, bletilla striata extract 2.0%, strontium chloride 0.45%; Potassium nitrate 0.9%, silicon dioxide 25.0%, sorbitol 38.0%, glycerol 2.0%, Polyethylene Glycol 3.0%, cellulose gum 0.3%, carrageenan is 0.3%, laurilsulfate sodium 2.2%, cocamido propyl betaine 0.6%, essence 1.2%, saccharin sodium 0.2%, surplus is pigment, antiseptic, water.
The processing technology of above-described embodiment 3 is identical with embodiment 1, does not add Folium Callicarpae Formosanae extract, Herba Agrimoniae extract in the present embodiment.
embodiment 4
Containing a Chinese medicine hemostasis toothpaste for Radix Notoginseng, its each constituent mass percent is: Radix Notoginseng extract 1.0%, Folium Callicarpae Formosanae extract 3.0%, Herba Agrimoniae extract 5.0%, strontium chloride 0.45%; Potassium nitrate 0.9%, silicon dioxide 21.0%, sorbitol 36.0%, glycerol 3.0%, Polyethylene Glycol 2.0%, cellulose gum 0.4%, carrageenan is 0.3%, laurilsulfate sodium 2.2%, cocamido propyl betaine 0.5%, essence 1.2%, saccharin sodium 0.2%, surplus is pigment, antiseptic, water.
The processing technology of above-described embodiment 4 is identical with embodiment 1, does not add bletilla striata extract in the present embodiment.
embodiment 5
Containing a Chinese medicine hemostasis toothpaste for Radix Notoginseng, its each constituent mass percent is: Radix Notoginseng extract 7.0%, Folium Callicarpae Formosanae extract 1.0%, bletilla striata extract 2.0%, Herba Agrimoniae extract 5.0%, strontium chloride 0.45%; Potassium nitrate 0.9%, calcium carbonate 10.0%, silica 1 8.0%, sorbitol 25.0%, glycerol 6.0%, Polyethylene Glycol 1.0%, cellulose gum 0.3%, carrageenan is 0.2%, laurilsulfate sodium 1.8%, cocamido propyl betaine 1.0%, essence 1.2%, saccharin sodium 0.2%, surplus is pigment, antiseptic, water.
The processing technology of above-described embodiment 5 is identical with embodiment 1.
comparative example 1
Containing a Chinese medicine hemostasis toothpaste for Radix Notoginseng, its each constituent mass percent is: Radix Notoginseng extract 7.0%, strontium chloride 0.45%; Potassium nitrate 0.9%, calcium carbonate 10.0%, silica 1 8.0%, sorbitol 25.0%, glycerol 6.0%, Polyethylene Glycol 1.0%, cellulose gum 0.3%, carrageenan is 0.2%, laurilsulfate sodium 1.8%, cocamido propyl betaine 1.0%, essence 1.2%, saccharin sodium 0.2%, surplus is pigment, antiseptic, water.
The processing technology of above-mentioned comparative example 1 is identical with embodiment 1.
comparative example 2
Containing a Chinese medicine hemostasis toothpaste for Radix Notoginseng, its each constituent mass percent is: Herba Agrimoniae extract 5.0%, strontium chloride 0.45%; Potassium nitrate 0.9%, calcium carbonate 10.0%, silica 1 8.0%, sorbitol 25.0%, glycerol 6.0%, Polyethylene Glycol 1.0%, cellulose gum 0.3%, carrageenan is 0.2%, laurilsulfate sodium 1.8%, cocamido propyl betaine 1.0%, essence 1.2%, saccharin sodium 0.2%, surplus is pigment, antiseptic, water.
The processing technology of above-mentioned comparative example 2 is identical with embodiment 1.
clinical experiment 1
Chinese medicine hemostasis toothpaste of the present invention is carried out clinical experiment, this toothpaste and the blank sample not adding any functional component carry out clinical verification together with product in contrast, hemorrhage for the gingivitis of two groups of experimenters index BOP% is compared, when meeting (contrast-experiment)/contrast >=15%, product has and improves gingival hemorrhage effect.
Table 1 toothpaste of the present invention and commercial toothpastes product contrast
| Sample | BOP baseline value | After 4 weeks | After 12 weeks |
| Containing Hemostatic of traditional herb medicine component dentifrice | 3.44% | 2.05 | 1.07 |
| Commercial toothpastes product | 3.95% | 3.12 | 1.69 |
From upper table 1 data: tested by double blind random, two kinds of toothpaste are used all to have no adverse reaction.Use toothpaste group of the present invention comparatively to use the BOP% of blank group toothpaste experimenter and the hemorrhage index of gingivitis to improve significantly, point out toothpaste of the present invention to have and significantly improve gingival hemorrhage effect.
According to the toothpaste that above-mentioned formula is made, user every day sooner or later once or have during gingival hemorrhage symptom and use, can alleviate the symptoms such as gingival hemorrhage, gingival swelling and pain, aphtha.Without the frequency using this product can reduce the appearance of gingiva problem during any symptom.
clinical experiment 2
The hemostasis toothpaste of embodiment 3-5 and comparative example 1-2 in the present invention, carry out clinical experiment, the blank sample of this toothpaste and single functional component carries out clinical verification together with product in contrast, hemorrhage for the gingivitis of two groups of experimenters index BOP% is compared, when meeting (contrast-experiment)/contrast >=15%, product has and improves gingival hemorrhage effect.
Table 2 Compound formula of toothpaste of the present invention and single effect tooth paste product contrast
| Sample | BOP baseline value | After 4 weeks | After 12 weeks |
| Embodiment 3 | 3.66% | 2.55 | 1.17 |
| Embodiment 4 | 3.45% | 2.45 | 1.09 |
| Embodiment 5 | 3.24% | 1.05 | 1.02 |
| Comparative example 1 | 4.55% | 3.10 | 2.69 |
| Comparative example 2 | 4.95% | 3.02 | 1.99 |
From upper table 2 data: tested by double blind random, all toothpaste is used all to have no adverse reaction.Use Compound formula of toothpaste group of the present invention compared with comparative example toothpaste experimenter, BOP% points out toothpaste of the present invention to have significantly to improve gingival hemorrhage effect.
The experimental example 5 of formula 4 Chinese medicine superpositions follows the comparative example 1 or 2 that is used alone of 4 Chinese medicines to contrast, and effect data is far longer than the result of use of independent Chinese medicine; Create beyond thought effect, relative to single Chinese medicine result of use, there is significance progress.
The present invention is not limited to above-mentioned preferred forms; anyone should learn the dosage or formula made under the present invention's enlightenment; and be the apparent changes of those skilled in the art, every have technical scheme that is identical or similar component with the present invention, all belongs to protection scope of the present invention.
Claims (7)
1. one kind has the Chinese medicinal toothpaste of hemostasis antiallergic sense effect, it is characterized in that: containing the Chinese medicine ingredients of 0.01% ~ 20% and the anti-sensitive composition of 1.35% in every 100g toothpaste matrix, its Chinese medicine ingredients is the mixing of in Radix Notoginseng, Folium Callicarpae Formosanae, Herba Agrimoniae, the Pseudobulbus Bletillae (Rhizoma Bletillae) two kinds or more; All the other are base ingredients, antiseptic, essence, pigment, water.
2. the Chinese medicinal toothpaste with hemostasis antiallergic sense effect according to claim 1, is characterized in that: containing 0.01% ~ 10% Radix Notoginseng composition in every 100g toothpaste matrix; Wherein Folium Callicarpae Formosanae, Herba Agrimoniae, Pseudobulbus Bletillae (Rhizoma Bletillae) addition are respectively 0.01% ~ 10.0%; When described Chinese medicine ingredients is applied in toothpaste, total addition level controls within 20.0% of toothpaste total amount.
3. the Chinese medicinal toothpaste with hemostasis antiallergic sense effect according to claim 1, is characterized in that: described Chinese medicine ingredients is the mixing of in Radix Notoginseng, Folium Callicarpae Formosanae, Herba Agrimoniae, the Pseudobulbus Bletillae (Rhizoma Bletillae) three kinds or four kinds; Described anti-sensitive composition is the mixing according to weight ratio 1:2 of strontium chloride and potassium nitrate.
4. the Chinese medicinal toothpaste with hemostasis antiallergic sense effect according to claim 1, it is characterized in that: described Chinese medicine ingredients is that medicinal plants extracts the bioactive ingredients obtained, the percentage by weight of described Chinese medicine ingredients and base ingredient is: Chinese medicine ingredients 0.1% ~ 20%, anti-sensitive composition 1.35%, grinding agent 15% ~ 55%, wetting agent 15% ~ 50%, adhesion agent 0.4% ~ 2%, foaming agent 0.5% ~ 4%, sweeting agent 0.05% ~ 0.3%, other compositions 0.01% ~ 10%.
5. the Chinese medicinal toothpaste with hemostasis antiallergic sense effect according to claim 3, is characterized in that: each raw material components comprising following percentage by weight:
Radix Notoginseng extract 0.01 ~ 10.0%;
Pseudobulbus Bletillae (Rhizoma Bletillae) extract 0.01 ~ 10.0%;
Herba Agrimoniae extract 0.1 ~ 5.0%;
Folium Callicarpae Formosanae extract 0.1 ~ 5.0%;
Strontium chloride 0.45%;
Potassium nitrate 0.9%;
Grinding agent 15% ~ 55%;
Wetting agent 15% ~ 50%;
Adhesion agent 0.4% ~ 2%;
Foaming agent 0.5% ~ 4%;
Sweeting agent 0.05% ~ 0.3%;
Antiseptic 0.01% ~ 0.8%;
Essence 0.5% ~ 2%;
Water surplus.
6. the Chinese medicinal toothpaste with hemostasis antiallergic sense effect according to claim 5, is characterized in that: described grinding agent is the mixture of one or more in hydrated silica, calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, aluminium hydroxide, microcrystalline Cellulose; Described wetting agent is the mixture of one or more in sorbitol, glycerol, Polyethylene Glycol, propylene glycol; Described adhesion agent is the mixture of one or more of cellulose gum, carrageenan, xanthan gum, guar gum; Described foaming agent is the mixture of one or more in laurilsulfate sodium, sodium lauroyl sarcosine, cocamido propyl betaine; Described sweeting agent is the mixture of one or more of saccharin sodium, sucralose, aspartame, and other compositions described are antiseptic, essence, water.
7. the Chinese medicinal toothpaste with hemostasis antiallergic sense effect according to claim 1, is characterized in that: also can add other both effectiveness raw materials in its formula, mothproof composition polyvinylpyrrolidone or sodium fluoride.
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| CN106177465A (en) * | 2016-08-24 | 2016-12-07 | 成都体九生物科技有限公司 | Toothpaste containing Radix Notoginseng extract and Pseudobulbus Bletillae (Rhizoma Bletillae) extract and preparation method thereof |
| CN106333866A (en) * | 2016-08-31 | 2017-01-18 | 重庆登康口腔护理用品股份有限公司 | High-salinity composition having functions of resisting dentine hypersensitivity and whitening, toothpaste and preparation method of toothpaste |
| CN107028799A (en) * | 2017-02-21 | 2017-08-11 | 广州薇美姿实业有限公司 | A kind of oral cavity baste of antiallergic whitening |
| CN107320390A (en) * | 2017-08-09 | 2017-11-07 | 何家平 | A kind of toothpaste containing Chinese herbal medicine |
| CN107362114A (en) * | 2017-08-06 | 2017-11-21 | 何家平 | A kind of sophora flower children's toothpaste |
| CN107468624A (en) * | 2017-10-18 | 2017-12-15 | 桂林大创科技有限公司 | A kind of toothpaste with hemostasis shield gum and preparation method thereof |
| CN108030735A (en) * | 2018-02-05 | 2018-05-15 | 苏州工业园区方津口腔诊所有限公司 | One kind hemostasis desensitizing toothpaste and preparation method thereof |
| CN115444781A (en) * | 2021-06-08 | 2022-12-09 | 广东雪洁日化用品有限公司 | Anti-allergy composition and preparation method and application thereof |
| CN116350564A (en) * | 2023-05-16 | 2023-06-30 | 浙江爱尚日用品有限公司 | Gum protecting and bleeding stopping toothpaste and preparation method thereof |
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