CN105748356A - Compound Herba Achilleae Alpinae bitter toothpaste - Google Patents
Compound Herba Achilleae Alpinae bitter toothpaste Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
- A61K36/855—Clerodendrum, e.g. glorybower
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The invention discloses compound Herba Achilleae Alpinae bitter toothpaste and belongs to a functional herbal toothpaste, effective in diminishing inflammation to stop bleeding, subsiding swelling to arrest pain, clearing fire and inhibiting bacteria, removing foul breath, preventing and treating oral ulcers and preventing or treating teeth and oral diseases, free of additional essence and pigment and capable of enabling fresh breath after usage.Following traditional herb extracts with effective active ingredients are added in a toothpaste preparation process: Herba Achilleae Alpinae extract, lavender extract, Radix Notoginseng extract, Folium et Cacumen Murrayae extract, Folium Isatidis extract and Radix Gentianae extract; the six herbal extracts are ideal auxiliary drugs for caring teeth and treating oral diseases and are safe and effective to apply in toothpaste production processes, the toothpaste is absorbed through oral mucosa during tooth brushing to enable prevention or treatment and is one of products popular with consumers.
Description
Technical field
One compound Artemisia rupestris bitterness toothpaste of the present invention, it is belonging to daily-use chemical industry oral-cavity article field, relate to a kind of effect type Chinese herbal toothpaste, efficacy active component Chinese herbal medicine extract is included by this toothpaste: Herba Achilleae extract, Herba Lysimachiae foenum-graeci extract, Radix Notoginseng extract, Folium Et Cacumen Murrayae extract, Folium Isatidis extract, Radix Gentianae extract, these six kinds of Chinese herbal medicine extract first Application are in the product process preparing toothpaste, this toothpaste is formed with toothpaste cream base and deionized water mixed preparing by efficacy active component Chinese herbal medicine extract, there is anti-inflammation hemostasia, reducing swelling and alleviating pain, relieve inflammation or internal heat antibacterial, dispel halitosis, the effect of anti-treating dental ulcer and prevention or treatment tooth and oral disease, the present invention also relates to the preparation technology of compound Artemisia rupestris bitterness toothpaste.
The present invention, without essence and pigment, is the innovative product in daily-use chemical industry oral-cavity article field, is effect type Chinese herbal toothpaste.
Background technology
Along with the constantly progress of science and technology and improving constantly of people's lives, nourishing healthy and health preserving conditioning to toothpaste are had higher requirement, and many toothpaste new varieties are arisen at the historic moment.Compound Artemisia rupestris bitterness toothpaste of the present invention is effect type Chinese herbal toothpaste, includes containing six kinds of Chinese herbal medicine extracts with efficacy active component: these six kinds of Chinese herbal medicine extracts of Herba Achilleae extract, Herba Lysimachiae foenum-graeci extract, Radix Notoginseng extract, Folium Et Cacumen Murrayae extract, Folium Isatidis extract, Radix Gentianae extract.Record according to traditional Chinese medical science pharmacopeia: Herba Achilleae has the effect of heat-clearing and toxic substances removing, anti-inflammatory analgetic；Lavandula angustifolia has the effect of fragrance, antiinflammatory, pain relieving；Radix Notoginseng has the effect of hemostasis, dissipating blood stasis, subduing swelling and relieving pain；Folium Et Cacumen Murrayae has the effect of pain relieving, detumescence, treatment toothache；Folium Isatidis has the effect of heat-clearing and toxic substances removing, removing heat from blood, hemostasis, treatment aphtha；Radix Gentianae has the fire of heat clearing and damp drying, eliminating pathogen in the liver gallbladder, prevents and treats the effect of bitter taste.The present invention is according to theory of Chinese medical science, reasonable compatibility, and all medicines are made a concerted effort, and formula is gentle, does not hinder oral mucosa.These six kinds of Chinese herbal medicine extracts are applied in formulation of tooth-paste and make toothpaste by the present invention first, its objective is to provide a kind of compound Artemisia rupestris bitterness toothpaste with anti-inflammation hemostasia, reducing swelling and alleviating pain, anti-treating dental ulcer, prevention or treatment tooth and oral disease effect, it is the natural plant type effect type Chinese herbal toothpaste without essence, pigment simultaneously, effect type Chinese herbal toothpaste that Ye Shi consumer expects.
Summary of the invention
The invention discloses a kind of compound Artemisia rupestris bitterness toothpaste containing medicinal herb components, being by Herba Achilleae extract, Herba Lysimachiae foenum-graeci extract, Radix Notoginseng extract, Folium Et Cacumen Murrayae extract, Folium Isatidis extract, Radix Gentianae extract, these six kinds of Chinese herbal medicine extracts add toothpaste cream base to and deionized water mixed preparing forms.This toothpaste have ordinary toothpaste cleaning dental functions while also there is anti-inflammation hemostasia, reducing swelling and alleviating pain, relieve inflammation or internal heat antibacterial, dispel halitosis and the effect of anti-treating dental ulcer; and there is protection oral mucosa; reduce oral disease; the effect of prevention or treatment tooth and oral disease; it it is a kind of effect type Chinese herbal toothpaste; use safety, evident in efficacy.
One compound Artemisia rupestris bitterness toothpaste of the present invention, described Herba Achilleae extract is the xeraphium of Herba Achilleae ethanol extraction, Herba Lysimachiae foenum-graeci extract is the xeraphium of lavandula angustifolia ethanol extraction, Radix Notoginseng extract is the xeraphium of Radix Notoginseng ethanol extraction, Folium Et Cacumen Murrayae extract is the xeraphium of Folium Et Cacumen Murrayae ethanol extraction, Folium Isatidis extract is the xeraphium of Folium Isatidis ethanol extraction, and Radix Gentianae extract is the xeraphium of Radix Gentianae ethanol extraction.
One compound Artemisia rupestris bitterness toothpaste of the present invention, described Herba Achilleae extract, Herba Lysimachiae foenum-graeci extract, Radix Notoginseng extract, Folium Et Cacumen Murrayae extract, Folium Isatidis extract, Radix Gentianae extract, these six kinds of Chinese herbal medicine extracts are not limited to such as the xeraphium of Herba Achilleae ethanol extraction, can also be used with supercritical extract, ultrasonic extraction thing, extracting solution, extractum extract, ground product, existing commercially available Chinese medicine extract can also be used, if be applied in toothpaste by other forms such as extracting solution or extractum, should be converted in the formula that disclosed in this invention by the addition in formula the addition of extract.
Cream base in compound Artemisia rupestris bitterness toothpaste of the present invention includes.
Abrasivus, accounting for the percentage by weight in toothpaste cream base is 20%-50%, can be selected for calcium carbonate, calcium hydrogen phosphate, silicon dioxide, sodium aluminosilicate, aluminium hydroxide and their combination.
Wetting agent, accounting for the percentage by weight in toothpaste cream base is 20% ~ 70%, can be selected for sorbitol, glycerol, propylene glycol, xylitol and their combination.
Foaming agent, accounting for the percentage by weight in toothpaste cream base is 1% ~ 3%, can be selected for sodium laurylsulfate, sodium N-lauroyl sarcosinate, sodium lauroyl glutamate, lauroyl sulfoacetic acid sodium.
Adhesive, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 2%, can be selected for sodium carboxymethyl cellulose, hydroxyethyl cellulose, xanthan gum, carrageenan, guar gum and their combination.
Aromatic, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 3%, can be selected for Oleum Menthae Rotundifoliae, Oleum menthae, wintergreen oil, Oleum Caryophylli, Oleum Anisi Stellati, Oleum Cinnamomi, Cladrastis kentukea Rudd oil, orange oil and their combination.
Efficacy active component Chinese herbal medicine extract includes: Herba Achilleae extract, and accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 30%；Herba Lysimachiae foenum-graeci extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Radix Notoginseng extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Folium Et Cacumen Murrayae extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Folium Isatidis extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Radix Gentianae extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%.
Preservative, accounting for the percentage by weight in toothpaste cream base is 0.05% ~ 1.5%, can be selected for sodium benzoate, methyl hydroxybenzoate, ethyl hydroxybenzoate, butoben and their combination.
Corrosion inhibiter, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 2%, can be selected for sodium silicate, calcium hydrogen phosphate, disodium hydrogen phosphate, sodium pyrophosphate, potassium nitrate and their combination.
Surplus is deionized water.
Six kinds of Chinese herbal medicine extracts containing efficacy active component are added in the product process preparing toothpaste by the present invention first, it is the reasonable compatibility of Chinese herbal medicine and toothpaste cream base, can play that prevention and treatment periodontitis, gingivitis, red swelling of gingiva be hemorrhage, oral ulcer and alleviate the effect of the diseases such as dental caries.
Compound Artemisia rupestris bitterness toothpaste of the present invention is to form according to theory of Chinese medical science reasonable compatibility, all medicines are made a concerted effort, play its effect, have anti-inflammation hemostasia, reducing swelling and alleviating pain, relieve inflammation or internal heat antibacterial, remove halitosis, anti-treating dental ulcer effect, there is oral cavity cleaning, breath freshening, comfortable taste, maintenance teeth whitening, attractive in appearance and healthy effect after use, there is the feature without essence, pigment, be a kind of natural plants effect type Chinese herbal toothpaste.
One compound Artemisia rupestris bitterness toothpaste of the present invention finds that oral ulcer, gingival hemorrhage, gingival swelling and pain, periodontitis, gingivitis, dental caries etc. are had certain treatment and prevention effect (referring to table 1) by clinical observation.
Table 1:
Detailed description of the invention.
Below by specific embodiment, the present invention being described in further detail, following example are illustrative, are not determinate, it is impossible to limit protection scope of the present invention with this.
One compound Artemisia rupestris bitterness toothpaste of the present invention, preparation process is by the Herba Achilleae extract measured, Herba Lysimachiae foenum-graeci extract, Radix Notoginseng extract, Folium Et Cacumen Murrayae extract, Folium Isatidis extract, Radix Gentianae extract, after these six kinds of Chinese herbal medicine extract xeraphiums and the toothpaste cream base measured and balance deionized water mixing and stirring through vacuum outgas, after the assay was approved, fill, sealing are made.
In 15 examples, toothpaste constitutive material is weight percent content below.
Example 1:
Compound Artemisia rupestris bitterness toothpaste is by calcium carbonate 40, glycerol 20, sodium laurylsulfate 1.5, hydroxyethyl cellulose 0.5, ethyl hydroxybenzoate 0.05, Oleum menthae 0.5, sodium pyrophosphate 0.5, Herba Achilleae extract 1, Herba Lysimachiae foenum-graeci extract 0.2, Radix Notoginseng extract 0.2, Folium Et Cacumen Murrayae extract 0.2, Folium Isatidis extract 0.2, Radix Gentianae extract 0.2, surplus is deionized water composition.After these 6 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound Artemisia rupestris bitterness toothpaste.
Example 2:
Compound Artemisia rupestris bitterness toothpaste is by calcium hydrogen phosphate 50, sorbitol 20, glycerol 5, sodium laurylsulfate 1.5, hydroxyethyl cellulose 0.7, ethyl hydroxybenzoate 0.06, Oleum menthae 0.8, sodium pyrophosphate 0.7, Herba Achilleae extract 1, Herba Lysimachiae foenum-graeci extract 2, Radix Notoginseng extract 1, Folium Et Cacumen Murrayae extract 2, Folium Isatidis extract 1, Radix Gentianae extract 1, surplus is deionized water composition.After these 6 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound Artemisia rupestris bitterness toothpaste.
Example 3:
Compound Artemisia rupestris bitterness toothpaste is by sorbitol 50, silicon dioxide 20, glycerol 10, sodium laurylsulfate 1.5, sodium carboxymethyl cellulose 0.8, ethyl hydroxybenzoate 0.15, Oleum menthae 0.8, sodium pyrophosphate 0.7, Herba Achilleae extract 6, Herba Lysimachiae foenum-graeci extract 1, Radix Notoginseng extract 3, Folium Et Cacumen Murrayae extract 2, Folium Isatidis extract 2, Radix Gentianae extract 1, surplus is deionized water composition.After these 6 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water base mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound Artemisia rupestris bitterness toothpaste.
Example 4:
Compound Artemisia rupestris bitterness toothpaste is by silica 15, sorbitol 60, propylene glycol 5, sodium laurylsulfate 1.8, hydroxyethyl cellulose 0.8, xanthan gum 0.4, carrageenan 0.3, sodium benzoate 0.3, Oleum menthae 1, calcium hydrogen phosphate 1, Herba Achilleae extract 10, Herba Lysimachiae foenum-graeci extract 2, Radix Notoginseng extract 3, Folium Et Cacumen Murrayae extract 3, Folium Isatidis extract 1, Radix Gentianae extract 1, surplus is deionized water composition.After these 6 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound Artemisia rupestris bitterness toothpaste.
Example 5:
Compound Artemisia rupestris bitterness toothpaste is by silica 18, sorbitol 65, propylene glycol 5; sodium N-lauroyl sarcosinate 2, hydroxyethyl cellulose 0.9, xanthan gum 0.6; ethyl hydroxybenzoate 0.15, sodium pyrophosphate 0.9, Mentholum 2; Herba Achilleae extract 6, Herba Lysimachiae foenum-graeci extract 6, Radix Notoginseng extract 6; Folium Et Cacumen Murrayae extract 2; Folium Isatidis extract 3, Radix Gentianae extract 3, surplus is deionized water composition.After these 6 kinds of Chinese herbal medicine extract xeraphiums above-mentioned and above-mentioned toothpaste cream base and balance deionized water mixing and stirring, through vacuum outgas, after the assay was approved, fill, sealing, obtain compound Artemisia rupestris bitterness toothpaste.
The invention is not limited in above-mentioned embodiment; anyone should learn the dosage or formula made under the enlightenment of the present invention; also be the apparent changes of those skilled in the art, every have with the present invention same or like like technical scheme formula, belong in protection scope of the present invention.
Claims (5)
1. a compound Artemisia rupestris bitterness toothpaste, this toothpaste cream base is by abrasivus, wetting agent, foaming agent, adhesive, aromatic, efficacy active component Chinese herbal medicine extract includes: Herba Achilleae extract, Herba Lysimachiae foenum-graeci extract, Radix Notoginseng extract, Folium Et Cacumen Murrayae extract, Folium Isatidis extract, Radix Gentianae extract, preservative, corrosion inhibiter and deionized water composition.
2. one compound Artemisia rupestris bitterness toothpaste of the present invention according to claim 1, it is characterized in that: described Herba Achilleae extract is the xeraphium of Herba Achilleae ethanol extraction, Herba Lysimachiae foenum-graeci extract is the xeraphium of lavandula angustifolia ethanol extraction, Radix Notoginseng extract is the xeraphium of Radix Notoginseng ethanol extraction, Folium Et Cacumen Murrayae extract is the xeraphium of Folium Et Cacumen Murrayae ethanol extraction, Folium Isatidis extract is the xeraphium of Folium Isatidis ethanol extraction, Radix Gentianae extract is the xeraphium of Radix Gentianae ethanol extraction, these six kinds of Chinese herbal medicine extracts have anti-inflammation hemostasia, reducing swelling and alleviating pain, relieve inflammation or internal heat antibacterial, dispel halitosis, the effect of anti-treating dental ulcer, it is added in toothpaste cream base, it is and the reasonable compatibility of toothpaste cream base, it it is desirable effective effect type Chinese herbal toothpaste.
3. one compound Artemisia rupestris bitterness toothpaste of the present invention according to claim 1, it is characterised in that: described cream base includes:
Abrasivus, accounting for the percentage by weight in toothpaste cream base is 20%-50%, can be selected for calcium carbonate, calcium hydrogen phosphate, silicon dioxide, sodium aluminosilicate, aluminium hydroxide and their combination；
Wetting agent, accounting for the percentage by weight in toothpaste cream base is 20% ~ 70%, can be selected for sorbitol, glycerol, propylene glycol, xylitol and their combination；
Foaming agent, accounting for the percentage by weight in toothpaste cream base is 1% ~ 3%, can be selected for sodium laurylsulfate, sodium N-lauroyl sarcosinate, sodium lauroyl glutamate, lauroyl sulfoacetic acid sodium and their combination；
Adhesive, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 2%, can be selected for sodium carboxymethyl cellulose, hydroxyethyl cellulose, xanthan gum, carrageenan, guar gum and their combination；
Aromatic, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 3%, can be selected for Oleum Menthae Rotundifoliae, Oleum menthae, wintergreen oil, Oleum Caryophylli, Oleum Anisi Stellati, Oleum Cinnamomi, Cladrastis kentukea Rudd oil, orange oil and their combination；
Efficacy active component Chinese herbal medicine extract includes: Herba Achilleae extract, and accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 30%；Herba Lysimachiae foenum-graeci extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Radix Notoginseng extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Folium Et Cacumen Murrayae extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Folium Isatidis extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；Radix Gentianae extract, accounting for the percentage by weight in toothpaste cream base is 0.1% ~ 20%；
Preservative, accounting for the percentage by weight in toothpaste cream base is 0.05% ~ 1.5%, can be selected for sodium benzoate, methyl hydroxybenzoate, ethyl hydroxybenzoate, butoben and their combination；
Corrosion inhibiter, accounting for the percentage by weight in toothpaste cream base is 0.5% ~ 2%, can be selected for sodium silicate, calcium hydrogen phosphate, disodium hydrogen phosphate, sodium pyrophosphate, potassium nitrate and their combination；
Surplus is deionized water.
4. one compound Artemisia rupestris bitterness toothpaste of the present invention according to claim 1, it is characterized in that: described Herba Achilleae extract, Herba Lysimachiae foenum-graeci extract, Radix Notoginseng extract, Folium Et Cacumen Murrayae extract, Folium Isatidis extract, Radix Gentianae extract, these six kinds of Chinese herbal medicine extracts are not limited to such as the xeraphium of Herba Achilleae ethanol extraction, can also be used with supercritical extract, ultrasonic extraction thing, extracting solution, extractum extract, ground product, existing commercially available Chinese medicine extract can also be used, if be applied in toothpaste by other forms such as extracting solution or extractum, should be converted in the formula that disclosed in this invention by the addition in formula the addition of extract.
5. one compound Artemisia rupestris bitterness toothpaste of the present invention according to claim 1, it is characterized in that: without essence, pigment in toothpaste cream base, this product compound Artemisia rupestris bitterness toothpaste has natural Chinese medicinal herb plant fragrance taste and micro-bitter taste of Chinese medicine, there are the stock solution true qualities of natural Chinese medicinal herb, have no side effect, be effect type Chinese herbal toothpaste of the conjunction of natural vegetable Chinese herbal medicine and toothpaste cream base.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106983683A (en) * | 2017-03-24 | 2017-07-28 | 新疆中草堂医药科技有限公司 | Application of the Radix Gentianae extract in bitter taste oral care product is prepared |
| CN107007502A (en) * | 2017-04-18 | 2017-08-04 | 新疆中草堂医药科技有限公司 | The oral care composition of noresidue sense |
| CN107412030A (en) * | 2017-03-20 | 2017-12-01 | 新疆中草堂医药科技有限公司 | Application of the Folium Isatidis extract in oral care product is prepared |
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| CN1554324A (en) * | 2003-09-24 | 2004-12-15 | 柳州两面针股份有限公司 | Chinese medicinal tooth-paste |
| JP2006022053A (en) * | 2004-07-08 | 2006-01-26 | Wakunaga Pharmaceut Co Ltd | Composition for oral cavity |
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| CN103767944A (en) * | 2012-10-24 | 2014-05-07 | 路明 | Traditional Chinese medicine anticarious toothpaste containing Chinese gentian root extract and sodium monofluorophosphate |
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| CN1554324A (en) * | 2003-09-24 | 2004-12-15 | 柳州两面针股份有限公司 | Chinese medicinal tooth-paste |
| JP2006022053A (en) * | 2004-07-08 | 2006-01-26 | Wakunaga Pharmaceut Co Ltd | Composition for oral cavity |
| JP2006022054A (en) * | 2004-07-08 | 2006-01-26 | Wakunaga Pharmaceut Co Ltd | Composition for oral cavity |
| CN103767944A (en) * | 2012-10-24 | 2014-05-07 | 路明 | Traditional Chinese medicine anticarious toothpaste containing Chinese gentian root extract and sodium monofluorophosphate |
| CN103655301A (en) * | 2013-11-26 | 2014-03-26 | 乌鲁木齐一枝好生物科技有限公司 | Tooth paste containing artemisia rupestris extract and preparation method thereof |
| CN105267083A (en) * | 2014-07-19 | 2016-01-27 | 王瑜 | Bamboo charcoal-lavender toothpaste |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412030A (en) * | 2017-03-20 | 2017-12-01 | 新疆中草堂医药科技有限公司 | Application of the Folium Isatidis extract in oral care product is prepared |
| CN106983683A (en) * | 2017-03-24 | 2017-07-28 | 新疆中草堂医药科技有限公司 | Application of the Radix Gentianae extract in bitter taste oral care product is prepared |
| CN107007502A (en) * | 2017-04-18 | 2017-08-04 | 新疆中草堂医药科技有限公司 | The oral care composition of noresidue sense |
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| CN105748356B (en) | 2019-09-10 |
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