CN105030955A - Medicine for treating appendicitis and preparation method thereof - Google Patents

Abstract

The invention discloses medicine for treating appendicitis and a preparation method thereof. The medicine is mainly prepared by mixing rhubarb, cortex moutan, peach kernels, waxgourd seeds, mirabilite, radix angelicae dahuricae, radix paeoniae rubra and caulis sargentodoxae with refine honey according to a certain weight ratio. The medicine has the effects of clearing heat, cooling blood, eliminating inflammation and relieving pain and is rapid to take the effects and good in treatment effect when the medicine is used for treating the appendicitis.

Description

One treats typhlitic medicine and preparation method thereof

Technical field

The present invention relates to one and treat typhlitic medicine and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Appendicitis is a kind of commonly encountered diseases.Often there are the performances such as the rising of right lower abdomen pain, body temperature, vomiting and neutrophilic leukocytosis clinically.Appendicitis is modal Abdominal Surgery.Western medical treatment is based on excision, but expenses of surgical treatment is high, has a big risk, and patient suffering is many.Therefore there is great demand to treatment by Chinese herbs in people.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally successfully have found the effectively typhlitic medicine for the treatment of, thus completes the present invention.

Object of the present invention is just to provide the typhlitic Chinese medicine composition of a kind of effectively treatment.

Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.

Medicine of the present invention selects Radix Et Rhizoma Rhei, Cortex Moutan, Semen Persicae, Semen Benincasae, Natrii Sulfas, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Caulis Sargentodoxae, Herba Patriniae, Herba Taraxaci medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat appendicitis.Wherein, select Radix Et Rhizoma Rhei to be because its nature and flavor are bitter, cold, enter stomach, large intestine, liver footpath, have the poison that purges heat, removing mass is stagnant, the function of clots absorbing blood, and control excess-heat constipation, delirium is gone mad, food stagnation feeling of fullness, dysentery is from the beginning of, tenesmus, and stasis of blood menolipsis closes lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinate red, carbuncle and ulcer toxic swelling, furuncle, burn.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle ， Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer, flutters damage.Semen Persicae is selected to be because its property bitter but sweet flavor, flat, enter the heart, liver, large intestine channel, have blood stasis removing and clots absorbing, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.

Semen Benincasae: have lung moistening, reduce phlegm, the function of eliminating carbuncle, diuretic, controls phlegm-heat cough, lung abscess, acute appendicitis, gonorrhea, edema, hemorrhoid.

Natrii Sulfas: have and purge heat, moisturizes, the function of softening the hard mass, and control excess-heat and stagnate, abdominal distention constipation, retention of phlegm gathers, and conjunctival congestion is hidden from view, erysipelas, carbuncle.

Select the Radix Angelicae Dahuricae to be that temperature, enters lung, spleen, stomach warp, dispel the wind, dampness because its nature and flavor are pungent, detumescence, the function of pain relieving, controls headache, supraorbital bone pain, toothache, nasal sinusitis, and cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Select Radix Paeoniae Rubra to be because its nature and flavor are bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, control warm poison and go mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， Epilepsy abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.

Caulis Sargentodoxae: different each DAHUOXUE, blood leads to, and be the ratan of Sargentodoxaceae plant Caulis Sargentodoxae, have heat-clearing and toxic substances removing, the function of expelling wind and activating blood circulation, controls acute appendicitis, acute mastitis, rheumatalgia, and amenorrhea is suffered from abdominal pain.

Herba Patriniae: have heat-clearing and toxic substances removing, the function of evacuation of pus removing blood stasis with potent drugs, controls acute appendicitis, dysentery, leucorrhea with red and white discharge, conjunctival congestion and swelling pain, carbuncle scabies.

Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:

Radix Et Rhizoma Rhei 140-160g, Cortex Moutan 140-160g, Semen Persicae 130-160g, Semen Benincasae 140-160g, Natrii Sulfas 80-100g, Radix Angelicae Dahuricae 140-160g, Radix Paeoniae Rubra 110-130g, Caulis Sargentodoxae 140-160g, Herba Patriniae 140-160g, Herba Taraxaci 140-160g.

Be preferably: Radix Et Rhizoma Rhei 150g, Cortex Moutan 150g, Semen Persicae 150g, Semen Benincasae 150g, Natrii Sulfas 90g, Radix Angelicae Dahuricae 150g, Radix Paeoniae Rubra 120g, Caulis Sargentodoxae 150g, Herba Patriniae 150g, Herba Taraxaci 150g.

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Radix Et Rhizoma Rhei: pick clean impurity, size stepping, moistening is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;

2, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;

3, Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;

4, Semen Benincasae: pick clean impurity, the used time smashs to pieces;

5, Natrii Sulfas: the Natrii Sulfas getting native crystal, filters with hot water dissolving, lets cool i.e. crystallization, common name Mirabilitum, get again Radix Raphani clean section, put in pot add water well-done after, add Mirabilitum and boil to dissolving completely altogether, take out after filtering or clarifying, get upper liquid to let cool, treat crystallization, after drying, be Natrii Sulfas, every Mirabilitum 100 jin, with Radix Raphani 10-20 jin;

6, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;

7, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;

8, Caulis Sargentodoxae: pick clean impurity, cleans, dries;

9, Herba Patriniae: summer gathers, dries after removing silt;

10, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;

Two, prepare

1, the Radix Et Rhizoma Rhei of described weight, Cortex Moutan, Semen Persicae, Semen Benincasae, Natrii Sulfas, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Caulis Sargentodoxae, Herba Patriniae, Herba Taraxaci mix homogeneously are ground to form fine powder

2, by the tender honey of Mel refining to 105-110 DEG C;

3, stick together grinding for the spice of fine powder adds mixing system in Mel by the part by weight of 1:1, then rubbing pill, every ball is containing pure medicine 1g.

Medicine of the present invention has heat clearing away, removing heat from blood, antiinflammatory, the function of pain relieving, is used for the treatment of appendicitis instant effect, good effect, does not recur.

In prescription, Cortex Moutan has the function of clearing away heat and cooling blood repercussive to be monarch drug, the stagnant clots absorbing blood of Radix Et Rhizoma Rhei removing mass, and Herba Taraxaci has effects for removing toxic heat, and three is ministerial drug; Three taste medicines play heat clearing away, removing heat from blood, antiinflammatory jointly, the effect of removing toxic substances, and treatment appendicitis effect is comprehensive, and with heat clearing away, antiinflammatory, removing toxic substances is that master can be effected a permanent cure; The Radix Angelicae Dahuricae dispels the wind, dampness, detumescence, and the function of pain relieving is adjuvant drug, and Radix Paeoniae Rubra clearing away heat and cooling blood eliminating stasis to stop pain is for making medicine, and all medicines take stopgap measures with being left, and said medicine is combined, and makes each efficacy of drugs produce synergism, thus can effectively treat typhlitic recurrence.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.

The animal toxicity test of [test example 1] medicine of the present invention

Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, be divided into two groups, often organize 15, wherein one group is normal amount test group, another group is overdose test group, the pure medicine of normal amount test group 0.1g/kg, overdose group 0.2g/kg, medicining mode adopts the administration of dilution administration by gavage, every day 2 times, take 5 days continuously, observe administration reaction every day, result shows that rabbit is movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's totally 30 examples for medical treatment.

2, diagnostic criteria

Appendicitis is clinical common surgical disease, and clinical manifestation is with transitivity Right Lower Abdomen pain, and with feeling sick, vomiting, the symptoms such as heating are main, and McBurney's point has tenderness, rebound tenderness, and laboratory leukocyte rises.

3, Therapeutic Method

The honeyed pill of above-mentioned preparation is taken to patient.Every day twice, each 5 balls, serve on 5.

4, efficacy assessment standard

Effective: appendicitis focus is eliminated, recovery from illness.

Take a turn for the better: abdominal pain alleviates, nausea and vomiting symptom takes a turn for the better, and the state of an illness is progressively recovered.

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form):

In above-mentioned treatment, by Drug therapy Appendicitis Patients 30 example of the present invention, effective 25 examples of result, obvious effective rate is 83.33%, and take a turn for the better 4 examples, and improvement rate is 13.33%, and total effective rate is 96.66%.

Claims (3)

1. the typhlitic medicine for the treatment of, it is characterized in that: he is made up of the crude drug in following weight range: Radix Et Rhizoma Rhei 140-160g, Cortex Moutan 140-160g, Semen Persicae 130-160g, Semen Benincasae 140-160g, Natrii Sulfas 80-100g, Radix Angelicae Dahuricae 140-160g, Radix Paeoniae Rubra 110-130g, Caulis Sargentodoxae 140-160g, Herba Patriniae 140-160g, Herba Taraxaci 140-160g.

2. medicine according to claim 1, wherein the materials of each raw material are: Radix Et Rhizoma Rhei 150g, Cortex Moutan 150g, Semen Persicae 150g, Semen Benincasae 150g, Natrii Sulfas 90g, Radix Angelicae Dahuricae 150g, Radix Paeoniae Rubra 120g, Caulis Sargentodoxae 150g, Herba Patriniae 150g, Herba Taraxaci 150g.

3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:

One, get the raw materials ready

1, Radix Et Rhizoma Rhei: pick clean impurity, size stepping, moistening is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;

2, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;

3, Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;

4, Semen Benincasae: pick clean impurity, the used time smashs to pieces;

5, Natrii Sulfas: the Natrii Sulfas getting native crystal, filters with hot water dissolving, lets cool i.e. crystallization, common name Mirabilitum, get again Radix Raphani clean section, put in pot add water well-done after, add Mirabilitum and boil to dissolving completely altogether, take out after filtering or clarifying, get upper liquid to let cool, treat crystallization, be awns after drying and disappear, every Mirabilitum 100 jin, with Radix Raphani 10-20 jin;

6, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;

7, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;

8, Caulis Sargentodoxae: pick clean impurity, cleans, dries;

9, Herba Patriniae: summer gathers, dries after removing silt;

10, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;

Two, prepare

1, by the Radix Et Rhizoma Rhei of described weight, Cortex Moutan, Semen Persicae, Semen Benincasae, Natrii Sulfas, the Radix Angelicae Dahuricae, Radix Paeoniae Rubra, Caulis Sargentodoxae, Herba Patriniae, Herba Taraxaci mix homogeneously grinds to form fine powder;

2, by the tender honey of Mel refining to 105-110 DEG C;

3, stick together grinding for the spice of fine powder adds mixing system in Mel by the part by weight of 1:1, then rubbing pill, every ball is containing pure medicine 1g.