CN104815306A - Medicine for treating acute cholecystitis and preparation method thereof - Google Patents

Medicine for treating acute cholecystitis and preparation method thereof Download PDF

Info

Publication number
CN104815306A
CN104815306A CN201510232024.4A CN201510232024A CN104815306A CN 104815306 A CN104815306 A CN 104815306A CN 201510232024 A CN201510232024 A CN 201510232024A CN 104815306 A CN104815306 A CN 104815306A
Authority
CN
China
Prior art keywords
radix
medicine
grams
gram
rhizoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510232024.4A
Other languages
Chinese (zh)
Inventor
高淑贤
Original Assignee
高淑贤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 高淑贤 filed Critical 高淑贤
Priority to CN201510232024.4A priority Critical patent/CN104815306A/en
Publication of CN104815306A publication Critical patent/CN104815306A/en
Pending legal-status Critical Current

Links

Abstract

The invention discloses a medicine for treating acute cholecystitis and a preparation method thereof, wherein the medicine is mainly prepared from following raw materials, according to a certain proportion by weight, radix bupleuri, rhubarb, hawthorn, white peony, fructus aurantii immaturus and scutellaria baicalensis. The medicine has the effects of purging heat toxin and breaking accumulation and stasis, harmonizing the exterior to release the interior, dispelling liver and raising yang, drying dampness and resolving phlegm, dispersing stuffiness and dissipating binds. The medicine is quick in effect, is good in curative effects and is free of toxic and side effect when being used for treating the acute cholecystitis.

Description

A kind of medicine for the treatment of acute cholecystitis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of acute cholecystitis and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Acute cholecystitis is a kind of common frdquently encountered disease, and main manifestations is right upper quadrant rest pain, paroxysmal colic, and scapular region diffuses to the right, how on the feed after greasy diet or midnight morbidity, often with Nausea and vomiting and heating.Cause of disease case is mainly in QI stagnation of the liver and galibladder and damp and hot heap soil or fertilizer over and around the roots resistance burnt.Treatment is with depressed liver-energy dispersing and QI regulating, and eliminating damp-heat is main.
Because Western medicine cannot effective fast treating acute cholecystitis, therefore there is great demand in the Chinese medicine of people to effective treatment acute cholecystitis, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment acute cholecystitis, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment acute cholecystitis.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Radix Bupleuri, Radix Et Rhizoma Rhei, Fructus Crataegi, Radix Paeoniae Alba, Fructus Aurantii Immaturus, Radix Scutellariae, the Rhizoma Pinelliae, Radix Curcumae, Rhizoma Zingiberis Recens medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat acute cholecystitis.Wherein, select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.Radix Et Rhizoma Rhei is selected to be that enter stomach, large intestine, liver footpath, have the poison that purges heat, removing mass is stagnant because its nature and flavor are bitter, cold, the function of clots absorbing blood, control excess-heat constipation, delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi , lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Select Fructus Crataegi be because its nature and flavor acid sweet, tepor, enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, taenifugal function, controls meat Ji , mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, puerperal after-pains, lochiorrhea, children's breast food stagnate.Select Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, return liver spleen channel, useful blood easing the affected liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls breast abdomen hypochondriac pain, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia.Select Fructus Aurantii Immaturus to be because its nature and flavor are bitter, cold, enter spleen, stomach warp, have dispelling the stagnated QI, loose painful abdominal mass, rush down expectorant, the function of removing food stagnancy, controls chest and abdomen swelling and pain, the thoracic obstruction, painful abdominal mass pain, accumulation of phlegm in the hypochondrium, edema, food stagnation, constipation, gastroptosis, uterine prolapse, proctoptosis.Radix Scutellariae is selected to be because its nature and flavor are bitter, cold, enter the heart, lung, gallbladder, large intestine channel, have removing the relative excess fire, except damp and hot, hemostasis, antiabortive function, controls high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tells, is defeated in battle, collapses, leaks, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.Select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, have drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass, control damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness, outer subduing inflammation.Radix Curcumae is selected to be because its nature and flavor are worked hard, cool, enter the heart, lung, Liver Channel, have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, control all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enter lung, stomach, spleen channel, deliver, cold expelling, preventing or arresting vomiting, open the function of expectorant, cure cold wind and cold, vomiting, and phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Radix Bupleuri 15-20 gram of Radix Et Rhizoma Rhei 10-14 Keshan short, bristly hair or beard 8-12 gram
Radix Paeoniae Alba 9-13 gram of Fructus Aurantii Immaturus 8-12 gram of Radix Scutellariae 8-12 gram
Rhizoma Pinelliae 7-11 gram of Radix Curcumae 8-12 gram of Rhizoma Zingiberis Recens 10-13 gram
Be preferably:
Radix Bupleuri 18 grams of Radix Et Rhizoma Rhei 12 Keshan short, bristly hair or beards 12 grams
Radix Paeoniae Alba 10 grams of Fructus Aurantii Immaturuss 10 grams of Radix Scutellariaes 10 grams
The Rhizoma Pinelliae 10 grams of Radix Curcumaes 10 grams, 12 grams, Rhizoma Zingiberis Recens
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry;
2, Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;
3, Fructus Crataegi: pick clean impurity, sieve enucleation;
4, Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull dry in the sun out, moisten to internal and external temperature even, section, dry;
5, Fructus Aurantii Immaturus: pick clean impurity, be soaked in water to eighty per cant thoroughly, pull out, profit, to interior without hard-core, cut into slices, is dried;
6, Radix Scutellariae: pick decontamination, removes residual stem, infiltrates or put in boiled water slightly to soak to pull out with cold water, and run through rear section and dry, attention is avoided tanning by the sun excessively rubescent;
7, the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
8, Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
9, Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices.
Two, prepare
1, the Radix Bupleuri of described weight, Radix Et Rhizoma Rhei, Fructus Crataegi, Radix Paeoniae Alba, Fructus Aurantii Immaturus, Radix Scutellariae, the Rhizoma Pinelliae, Radix Curcumae, Rhizoma Zingiberis Recens material medicine are put into decocting container to add water 6 times amount, soak after 120 minutes, intense fire decocts boiling, again with slow fire boiling within 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
2, add water the medicinal residues of filtration 5 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, pours in container by second time decoction liquor;
3, twice decoction liquor is carried out mixing and stirring, be divided into 2 doses and take.
In prescription, Radix Bupleuri has reconciling superficies and interior, soothing the liver, the function of yang invigorating is monarch drug, Radix Et Rhizoma Rhei purges heat poison, removing mass is stagnant, clots absorbing blood, the Rhizoma Pinelliae has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass, the two is ministerial drug, three taste medicines play the poison that purges heat jointly, removing mass is stagnant, soothing the liver yang invigorating, with in table solution, drying dampness to eliminate phlegm, the effect of dissolving lump and resolving mass, treatment acute cholecystitis effect is comprehensive, and with soothing the liver yang invigorating, dissolving lump and resolving mass is main, can effect a permanent cure, Radix Curcumae circulation of qi promoting solution with, removing heat from blood removing blood stasis with potent drugs is adjuvant drug, the useful blood easing the affected liver of Radix Paeoniae Alba, the function of pain relieving in slow, for making medicine, all medicines take stopgap measures with being left.
Medicine of the present invention has the poison that purges heat, blood stasis expelling blood, beneficial blood easing the affected liver, pain relieving in slow, and the function of dissolving lump and resolving mass, is used for the treatment of acute cholecystitis, short treating period, instant effect, non-relapse after healing, has no side effect.
Detailed description of the invention:
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 10, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept acute cholecystitis out-patient totally 44 examples for medical treatment.
2, diagnostic criteria
1. pain upper right abdomen severe pain or angor, mostly is calculus or parasite incarceration and blocks acute cholecystitis caused by neck of gallbladder; Pain often breaks out, and very acutely, or present angor sample, pain presents radioactivity, and modal radiation position is the place such as right shoulder and right inferior angle of scapula, is be that gallbladder inflammation stimulates caused by right phrenic nerves tip and stomach wall peripheral nerve;
2. Nausea and vomiting is modal symptom, as obstinate in Nausea and vomiting or frequent, can cause dehydration, collapse and electrolyte disturbance, is more common in calculus or ascarid when blocking cystic duct;
3. fear of cold, shiver with cold, the light-duty case of heating often have fear of cold and low grade fever; Heavy case then can have shiver with cold and high heat, and temperature can reach more than 39 DEG C, and can occur the mental symptom such as delirium, delirium;
4. jaundice is more rare, comparatively light if any the general degree of jaundice, represents to infect to have spread to liver through lymphatic vessel, cause hepatic injury, or inflammation invades common bile duct.
3, Therapeutic Method
Selecting above-mentioned medicament, take to patient, each serving with 1 dose, took 1 time every 4 hours, 7 days is a course for the treatment of, takes 2 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: acute cholecystitis transference cure, recovery from illness, body constitution recovers normal;
Take a turn for the better: acute cholecystitis pain symptom is eliminated, and disease is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy acute cholecystitis patient 44 example of the present invention, effective 39 examples of result, obvious effective rate is 88.63%, and take a turn for the better 4 examples, and improvement rate is 9.09%, and invalid 1 example, total effective rate is 97.73%.

Claims (3)

1. treat a medicine for acute cholecystitis, it is characterized in that: it is made up of the crude drug in following weight range:
Radix Bupleuri 15-20 gram of Radix Et Rhizoma Rhei 10-14 Keshan short, bristly hair or beard 8-12 gram
Radix Paeoniae Alba 9-13 gram of Fructus Aurantii Immaturus 8-12 gram of Radix Scutellariae 8-12 gram
Rhizoma Pinelliae 7-11 gram of Radix Curcumae 8-12 gram of Rhizoma Zingiberis Recens 10-13 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Bupleuri 18 grams of Radix Et Rhizoma Rhei 12 Keshan short, bristly hair or beards 12 grams of Radix Paeoniae Alba 10 grams
12 grams, Fructus Aurantii Immaturus 10 grams of Radix Scutellariaes 10 grams of Rhizoma Pinelliaes 10 grams of Radix Curcumaes 10 grams of Rhizoma Zingiberis Recenss.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry;
(2) Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;
(3) Fructus Crataegi: pick clean impurity, sieve enucleation;
(4) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull dry in the sun out, moisten to internal and external temperature even, section, dry;
(5) Fructus Aurantii Immaturus: pick clean impurity, be soaked in water to eighty per cant thoroughly, pull out, profit, to interior without hard-core, cut into slices, is dried;
(6) Radix Scutellariae: pick decontamination, removes residual stem, infiltrates or put in boiled water slightly to soak to pull out with cold water, and run through rear section and dry, attention is avoided tanning by the sun excessively rubescent;
(7) Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
(8) Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
(9) Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
(2) prepare
(1) Radix Bupleuri of described weight, Radix Et Rhizoma Rhei, Fructus Crataegi, Radix Paeoniae Alba, Fructus Aurantii Immaturus, Radix Scutellariae, the Rhizoma Pinelliae, Radix Curcumae, Rhizoma Zingiberis Recens material medicine are put into decocting container to add water 6 times amount, soak after 120 minutes, intense fire decocts boiling, again with slow fire boiling within 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
(2) add water the medicinal residues of filtration 5 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, pours in container by second time decoction liquor;
(3) twice decoction liquor is carried out mixing and stirring, be divided into 2 doses and take.
CN201510232024.4A 2015-05-09 2015-05-09 Medicine for treating acute cholecystitis and preparation method thereof Pending CN104815306A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510232024.4A CN104815306A (en) 2015-05-09 2015-05-09 Medicine for treating acute cholecystitis and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510232024.4A CN104815306A (en) 2015-05-09 2015-05-09 Medicine for treating acute cholecystitis and preparation method thereof

Publications (1)

Publication Number Publication Date
CN104815306A true CN104815306A (en) 2015-08-05

Family

ID=53725946

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510232024.4A Pending CN104815306A (en) 2015-05-09 2015-05-09 Medicine for treating acute cholecystitis and preparation method thereof

Country Status (1)

Country Link
CN (1) CN104815306A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105250963A (en) * 2015-11-04 2016-01-20 安徽益健堂中药饮片科技有限公司 Traditional Chinese medicine composition for treating cholecystitis and gall-stone

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1430996A (en) * 2003-01-15 2003-07-23 南通精华制药有限公司 Oral prepn. of big bupleurum root and its prodn. methods
CN1654057A (en) * 2004-02-10 2005-08-17 湖北丽益医药科技有限公司 Chinese medicine composition for treating acute cholecystitis and preparing method thereof
CN102847089A (en) * 2011-06-30 2013-01-02 苏州知微堂生物科技有限公司 Preparation process of integration-type novel formulation of DACHAIHU decoction and a production method thereof
CN103446555A (en) * 2012-05-30 2013-12-18 付勇 Chinese medicinal composition for treating cholecystitis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1430996A (en) * 2003-01-15 2003-07-23 南通精华制药有限公司 Oral prepn. of big bupleurum root and its prodn. methods
CN1654057A (en) * 2004-02-10 2005-08-17 湖北丽益医药科技有限公司 Chinese medicine composition for treating acute cholecystitis and preparing method thereof
CN102847089A (en) * 2011-06-30 2013-01-02 苏州知微堂生物科技有限公司 Preparation process of integration-type novel formulation of DACHAIHU decoction and a production method thereof
CN103446555A (en) * 2012-05-30 2013-12-18 付勇 Chinese medicinal composition for treating cholecystitis

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
刘汝荣: "大柴胡汤临床应用举隅", 《实用中医药杂志》 *
刘渡舟: "大柴胡汤治验五例", 《陕西中医》 *
秋增超: "自拟柴芍夏芩汤治疗急性胆囊炎120例", 《陕西中医》 *
翟阳蕾等: "王裕颐运用经方治验举隅", 《山西中医》 *
赵素丽: "大柴胡汤治验六则", 《河南中医》 *
陈令江等: "龙胆泻肝汤加减治疗急性胆囊炎81例", 《吉林中医药》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105250963A (en) * 2015-11-04 2016-01-20 安徽益健堂中药饮片科技有限公司 Traditional Chinese medicine composition for treating cholecystitis and gall-stone

Similar Documents

Publication Publication Date Title
CN103638501B (en) Medicament for treating biliary ascariasis and preparation method of medicament
CN102552855B (en) Medicine for treating gastrectasia and preparation method thereof
CN102793822B (en) Medicament for treating appendicitis and preparation method thereof
CN103736034B (en) A kind of medicine for the treatment of cholecystitis and preparation method thereof
CN104474471A (en) Traditional Chinese medicine composition for treating thyroid
CN105477487A (en) Medicine for treating chronic pharyngitis and preparation method thereof
CN103816417A (en) Traditional Chinese medicine composition for treating infantile convulsion and preparation method thereof
CN102805843A (en) Drug for curing stomachache and preparation method thereof
CN104958626A (en) Medicine for treating colitis and preparation method thereof
CN106620519A (en) Drug for treating mammitis and preparation method thereof
CN105457001A (en) Medicine for treating attention-deficit hyperactivity disorder and preparation method of medicine
CN105412665A (en) Medicine for treating measles and preparation method thereof
CN104815306A (en) Medicine for treating acute cholecystitis and preparation method thereof
CN104352995A (en) Medicine for treating gall-stone and preparation method thereof
CN106924694A (en) It is a kind of to treat medicine of habitual constipation and preparation method thereof
CN102657773B (en) Medicament for treating appendicitis and preparation method thereof
CN103191352B (en) Medicine for treating pelvic inflammation and preparation method thereof
CN105343582A (en) Medicine for treating tetanus and preparation method thereof
CN106421357A (en) Medicine for treating recurrent oral ulceration and preparing method thereof
CN105412825A (en) Drug for treating hyperlipidaemia and preparation method thereof
CN102988883B (en) Medicament for treating pneumonia and preparation method of medicament
CN105435034A (en) Medicine for treating hemoptysis and preparation method thereof
CN102657727B (en) Medicine for treating colonitis and preparation method thereof
CN105343863A (en) Medicine for treating benign ovarian cyst and preparation method of medicine
CN105477600A (en) Drug for treating prolonged lochiorrhea and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
C06 Publication
SE01 Entry into force of request for substantive examination
EXSB Decision made by sipo to initiate substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20150805

RJ01 Rejection of invention patent application after publication