CN105001293A - 雌酚酮的制备方法 - Google Patents
雌酚酮的制备方法 Download PDFInfo
- Publication number
- CN105001293A CN105001293A CN201510316931.7A CN201510316931A CN105001293A CN 105001293 A CN105001293 A CN 105001293A CN 201510316931 A CN201510316931 A CN 201510316931A CN 105001293 A CN105001293 A CN 105001293A
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- Prior art keywords
- estrone
- preparation
- add
- ketal
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- WMBXCENLBHSSQE-ASKATJPDSA-N CC[C@H](C(C)[C@@H](C)CCC[IH]C)N(C)O Chemical compound CC[C@H](C(C)[C@@H](C)CCC[IH]C)N(C)O WMBXCENLBHSSQE-ASKATJPDSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
Abstract
Description
Claims (10)
Priority Applications (1)
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CN201510316931.7A CN105001293B (zh) | 2015-06-10 | 2015-06-10 | 雌酚酮的制备方法 |
Applications Claiming Priority (1)
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CN201510316931.7A CN105001293B (zh) | 2015-06-10 | 2015-06-10 | 雌酚酮的制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN105001293A true CN105001293A (zh) | 2015-10-28 |
CN105001293B CN105001293B (zh) | 2017-10-20 |
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CN201510316931.7A Active CN105001293B (zh) | 2015-06-10 | 2015-06-10 | 雌酚酮的制备方法 |
Country Status (1)
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CN (1) | CN105001293B (zh) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105481896A (zh) * | 2015-12-03 | 2016-04-13 | 浙江大学 | 一种地马格列的制备方法 |
CN106866764A (zh) * | 2017-02-14 | 2017-06-20 | 岳阳环宇药业有限公司 | 一种雌二醇的制备工艺及其制备系统 |
CN107602650A (zh) * | 2017-10-16 | 2018-01-19 | 中国科学院上海有机化学研究所 | 一种雌酚酮的合成方法 |
CN110746477A (zh) * | 2019-11-05 | 2020-02-04 | 江西宇能制药有限公司 | 一种雌酚酮的全合成制备方法 |
CN111205056A (zh) * | 2020-01-16 | 2020-05-29 | 佛冈豪鑫环保建材有限公司 | 一种利用建筑废料的保温砌块砖 |
CN114315942A (zh) * | 2021-12-29 | 2022-04-12 | 浙江仙居君业药业有限公司 | 一种雌酚酮的合成方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5549398A (en) * | 1978-10-03 | 1980-04-09 | Mitsubishi Chem Ind Ltd | Preparation of estrone |
JPS5551099A (en) * | 1978-10-12 | 1980-04-14 | Mitsubishi Chem Ind Ltd | Preparation of estrone |
RU2170740C1 (ru) * | 2000-02-22 | 2001-07-20 | Закрытое акционерное общество "ПЕНТКРОФТ ФАРМА" | Способ получения d-эстра-1,3,5(10)-триен-3-ол-17-она (эстрона) |
-
2015
- 2015-06-10 CN CN201510316931.7A patent/CN105001293B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5549398A (en) * | 1978-10-03 | 1980-04-09 | Mitsubishi Chem Ind Ltd | Preparation of estrone |
JPS5551099A (en) * | 1978-10-12 | 1980-04-14 | Mitsubishi Chem Ind Ltd | Preparation of estrone |
RU2170740C1 (ru) * | 2000-02-22 | 2001-07-20 | Закрытое акционерное общество "ПЕНТКРОФТ ФАРМА" | Способ получения d-эстра-1,3,5(10)-триен-3-ол-17-она (эстрона) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105481896A (zh) * | 2015-12-03 | 2016-04-13 | 浙江大学 | 一种地马格列的制备方法 |
CN106866764A (zh) * | 2017-02-14 | 2017-06-20 | 岳阳环宇药业有限公司 | 一种雌二醇的制备工艺及其制备系统 |
CN106866764B (zh) * | 2017-02-14 | 2018-05-25 | 岳阳环宇药业有限公司 | 一种雌二醇的制备工艺及其制备系统 |
CN107602650A (zh) * | 2017-10-16 | 2018-01-19 | 中国科学院上海有机化学研究所 | 一种雌酚酮的合成方法 |
CN110746477A (zh) * | 2019-11-05 | 2020-02-04 | 江西宇能制药有限公司 | 一种雌酚酮的全合成制备方法 |
CN110746477B (zh) * | 2019-11-05 | 2021-11-05 | 江西宇能制药有限公司 | 一种雌酚酮的全合成制备方法 |
CN111205056A (zh) * | 2020-01-16 | 2020-05-29 | 佛冈豪鑫环保建材有限公司 | 一种利用建筑废料的保温砌块砖 |
CN114315942A (zh) * | 2021-12-29 | 2022-04-12 | 浙江仙居君业药业有限公司 | 一种雌酚酮的合成方法 |
WO2023126014A1 (zh) * | 2021-12-29 | 2023-07-06 | 浙江仙居君业药业有限公司 | 一种雌酚酮的合成方法 |
CN114315942B (zh) * | 2021-12-29 | 2023-10-17 | 浙江仙居君业药业有限公司 | 一种雌酚酮的合成方法 |
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Publication number | Publication date |
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CN105001293B (zh) | 2017-10-20 |
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Effective date of registration: 20190308 Address after: 317300 Lingxiu Road, Yangfu Industrial Park, Xianju County, Taizhou City, Zhejiang Province Co-patentee after: JIANGXI JUNYE BIOLOGICAL PHARMACEUTICAL CO.,LTD. Patentee after: ZHEJIANG XIANJU JUNYE PHARMACEUTICAL Co.,Ltd. Address before: 317300 Junye Road, Xianju County, Taizhou City, Zhejiang Province (Hebu Bridge Head) Patentee before: ZHEJIANG XIANJU JUNYE PHARMACEUTICAL Co.,Ltd. |
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Effective date of registration: 20230421 Address after: 317300 Junye Road, Xianju County, Taizhou City, Zhejiang Province Patentee after: ZHEJIANG XIANJU JUNYE PHARMACEUTICAL Co.,Ltd. Patentee after: JIANGXI JUNYE BIOLOGICAL PHARMACEUTICAL CO.,LTD. Patentee after: Inner Mongolia Junye Biological Pharmaceutical Co.,Ltd. Address before: 317300 Lingxiu Road, Yangfu Industrial Park, Xianju County, Taizhou City, Zhejiang Province Patentee before: ZHEJIANG XIANJU JUNYE PHARMACEUTICAL Co.,Ltd. Patentee before: JIANGXI JUNYE BIOLOGICAL PHARMACEUTICAL CO.,LTD. |