CN104888193A - 用于治疗微生物病症的组合物和方法 - Google Patents

用于治疗微生物病症的组合物和方法 Download PDF

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Publication number
CN104888193A
CN104888193A CN201510262894.6A CN201510262894A CN104888193A CN 104888193 A CN104888193 A CN 104888193A CN 201510262894 A CN201510262894 A CN 201510262894A CN 104888193 A CN104888193 A CN 104888193A
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Prior art keywords
antibody
reg
seq
cell
polypeptide
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Pending
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CN201510262894.6A
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Chinese (zh)
Inventor
亚历山大.R.阿巴斯
迪米特里.M.达尼兰科
弗雷德里克.J.德索瓦格
尼科.P.吉拉蒂
佐拉.莫德鲁桑
欧阳文军
帕特里夏.A.瓦尔德兹
郑衍
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Genentech Inc
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Genentech Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CN201510262894.6A 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法 Pending CN104888193A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US98617007P 2007-11-07 2007-11-07
US60/986,170 2007-11-07
US1362007P 2007-12-13 2007-12-13
US61/013,620 2007-12-13
US1562007P 2007-12-20 2007-12-20
US61/015,620 2007-12-20
CN2008801241737A CN101951945A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2008801241737A Division CN101951945A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法

Publications (1)

Publication Number Publication Date
CN104888193A true CN104888193A (zh) 2015-09-09

Family

ID=40551983

Family Applications (5)

Application Number Title Priority Date Filing Date
CN201510262894.6A Pending CN104888193A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法
CN2011101151819A Pending CN102172395A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法
CN201811093788.XA Pending CN108815508A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法
CN2008801241737A Pending CN101951945A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法
CN2013100500120A Pending CN103142999A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
CN2011101151819A Pending CN102172395A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法
CN201811093788.XA Pending CN108815508A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法
CN2008801241737A Pending CN101951945A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法
CN2013100500120A Pending CN103142999A (zh) 2007-11-07 2008-11-07 用于治疗微生物病症的组合物和方法

Country Status (26)

Country Link
US (4) US20090202475A1 ( )
EP (3) EP3360567A1 ( )
JP (3) JP5985150B2 ( )
KR (2) KR101867606B1 ( )
CN (5) CN104888193A ( )
AU (1) AU2008323770B2 ( )
CA (1) CA2705007A1 ( )
CO (1) CO6280406A2 ( )
DK (1) DK2514436T3 ( )
ES (1) ES2662845T3 ( )
HK (2) HK1214137A1 ( )
HR (1) HRP20180445T1 ( )
HU (1) HUE038588T2 ( )
IL (2) IL205623A0 ( )
LT (1) LT2514436T ( )
MX (2) MX2010005108A ( )
NO (1) NO2514436T3 ( )
PH (1) PH12013501074A1 ( )
PL (1) PL2514436T3 ( )
PT (1) PT2514436T ( )
RS (1) RS57021B1 ( )
RU (1) RU2503460C2 ( )
SG (2) SG10202007210RA ( )
SI (1) SI2514436T1 ( )
WO (1) WO2009062102A2 ( )
ZA (1) ZA201003113B ( )

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CN108976289A (zh) * 2015-11-20 2018-12-11 深圳市南山区人民医院 用于预防和治疗肠致病大肠杆菌感染的肽段

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AU2009320061A1 (en) * 2008-11-03 2010-06-03 Merck Sharp & Dohme Corp. Inflammatory bowel disease biomarkers and related methods of treatment
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CN102260343A (zh) 2010-05-25 2011-11-30 健能隆医药技术（上海）有限公司 重组人g-csf二聚体在治疗神经损伤疾病中的用途
CN102380091A (zh) 2010-08-31 2012-03-21 健能隆医药技术（上海）有限公司 白介素-22在治疗病毒性肝炎中的应用
CN103732240B (zh) 2011-07-25 2015-12-09 健能隆医药技术（上海）有限公司 G-csf二聚体在制备治疗神经退行性疾病药物中的应用
EP2788762B1 (en) 2011-12-05 2018-08-15 The Trustees Of The University Of Pennsylvania Graphene-biomolecule bioelectronic devices
CN102559759A (zh) * 2011-12-19 2012-07-11 西安交通大学医学院第一附属医院 Hip/pap重组腺病毒及其抗溃疡性结肠炎的应用
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