CN104622924B - A kind of medicine and its production technology for treating rhinitis - Google Patents
A kind of medicine and its production technology for treating rhinitis Download PDFInfo
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- CN104622924B CN104622924B CN201410319819.4A CN201410319819A CN104622924B CN 104622924 B CN104622924 B CN 104622924B CN 201410319819 A CN201410319819 A CN 201410319819A CN 104622924 B CN104622924 B CN 104622924B
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Abstract
The invention discloses a kind of medicine for treating rhinitis, it is made up of honeycomb and the root of Dahurain angelica, at least one following Chinese medicine can be added wherein：The flower bud of lily magnolia, Radix Angelicae Sinensis, radix bupleuri, stir-baked FRUCTUS GARDENIAE, radix scrophulariae, fritillaria and at least one following Western medicine：Cetirizine Hydrochloride, promethazine hydrochloride, azelastine hydrochloride.The invention also discloses a kind of production technology for the medicine for treating rhinitis, comprise the following steps：（1）Raw material is crushed；（2）Add other Chinese medicines and/or Western medicine；（3）Pill or capsule is made in above-mentioned mixing powder.The invention also discloses a kind of production technology for the medicine for treating rhinitis, comprise the following steps：（1）Honeycomb is boiled with root of Dahurain angelica water；（2）Add other Chinese medicines and/or Western medicine；（3）Filtering；（4）Propolis and beta cyclodextrin are added, water decoction, oral liquid or electuary is made.Therapeutic effect of the present invention is good, and materials are easy, cheap, and nutritive value utilization rate is high.
Description
Technical field
The present invention relates to field of medicaments, more particularly, to a kind of formula of Chinese herbal medicine.
Background technology
Rhinitis is nasal cavity inflammatory disease, is virus, bacterium, allergen, various physical and chemical factors and some systemic diseases
The inflammation of caused bronchia mucosal.The main pathological change of rhinitis is bronchia mucosal hyperemia, swelling, ooze out, hyperplasia, atrophy or bad
Wait indefinitely.
Chinese patent CN101084920A discloses a kind of medicine for treating nasal inflammation, has used borax, mirabilite and alum,
Function in the energy short time, has no side effect, but can not effect a radical cure persistent ailment, can only temporarily suppress rhinitis.Chinese patent
CN101618100A discloses a kind of anti-rhinitis medicament and its production technology, has used the Chinese medicine of a variety of anti-inflammation and sterilizations, from raising body
Rhinitis is resisted in terms of matter, but short-term drug effect is general, can not effect a radical cure rhinitis.Chinese patent CN102240377A discloses one
The formula of drug for treating rhinitis is planted, based on Chinese medicine " taking deep soup ", the Chinese medicine of a few taste air making-up and spleen enlivenings is with the addition of, so as to improve " taking deep soup "
Curative effect, but composition is excessively various, and some Chinese medicines materials are difficult, on the high side.
The content of the invention
Difficult to solve existing drug for treating rhinitis materials, the problem of on the high side, we have proposed a kind of medicine for treating rhinitis
And its production technology.
The present invention is achieved by the following technical solutions：The present invention provides a kind of medicine for treating rhinitis, the medicine
It is made up of the bulk drug of following parts by weight：Honeycomb 500, the root of Dahurain angelica 30 ~ 100.Wangkai is good（1981）Deng report, honeycomb preparation for treating is used
Rhinitis, total effective rate is up to 82%, and honeycomb is sweet, mild-natured, detoxicating and destroying parasites, wind-expelling pain-stopping.Root of Dahurain angelica pungent-warm, inducing diaphoresis to dispel wind can dissipate wind
Cold, clearing the nasal passage is only had a headache.Volatile oil in nidus vespae has suitable toxicity to experimental animal, and acute nephritis etc. may be caused to damage,
And root of Dahurain angelica kidney tonifying is smart, the side effect of honeycomb is eliminated to a certain extent, and improves the therapeutic effect to rhinitis.
Preferably, said medicine is made up of the bulk drug of following parts by weight：Honeycomb 500, the root of Dahurain angelica 40 ~ 60.
Above-mentioned honeycomb is, without nest worm, without the nest spleen gone mouldy, 2-3 honeycomb to be used preferably on bee farm.Old honeycomb is
The honeycomb of more than 3 years, is that the beeswax of honeybee itself secretion is built and formed.Honeycomb is mainly honeybee and is bred in beehive, stores king
Slurry, honey, Bee Pollen, propolis etc..The honeycomb newly built is white or light brown, stored wherein by honeybee honey, pollen,
Royal jelly etc., these compositions infiltration lair, makes it contain these materials.Honeybee carries out development by metamorphosis in honeycomb, sprouts wings and room
Afterwards, one layer of husks is left with honeycomb, so, honeycomb gradually becomes brown, and final color is changed into dark brown.It is general to pass through
3 years, the new honeybee in or so 20 generations is about fed, the husks that lair intraocular wall leaves gradually thickeies, and volume is less and less, be old
Spleen.
The medicine of above-mentioned treatment rhinitis, the Chinese medicine of 0 ~ 6 kind of following parts by weight can be also added wherein：The flower bud of lily magnolia 6 ~ 20, Radix Angelicae Sinensis
30 ~ 60, radix bupleuri 3 ~ 20, stir-baked FRUCTUS GARDENIAE 10 ~ 30, radix scrophulariae 40 ~ 60, fritillaria 5 ~ 20.《Dialectical record》In have Chinese medicine " taking deep soup " be formulated and
Discuss, the flower bud of lily magnolia can most enter courage, draw Radix Angelicae Sinensis with the gas of cerebrum tonifying, draw radix scrophulariae to solve the fire of brain；Plus radix bupleuri, cape jasmine are with strongly fragrant in the courage that relaxes
Heat, then courage do not help fire, and from the benefit by tonifying Qi.Gas in the tears person not gone in only nose so, cephalocathartic in fire, beneficial brain, just
So only.
The flower bud of lily magnolia：It is pungent, temperature；Attach to the lung and stomach meridians.Cold-dispelling, clearing the nasal passage；For anemofrigid headache, nasal obstruction, nasosinusitis, turbid nasal discharge.
Radix Angelicae Sinensis：It is sweet, pungent, temperature；Return liver, the heart, the spleen channel；Enrich blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.
Radix bupleuri：Bitter, puts down.Main trusted subordinate, goes to tie gas in stomach, and diet accumulation, fever and chills perverse trend pushes away Chen Zhixin.
Stir-baked FRUCTUS GARDENIAE：Heat-clearing, purging intense heat, cool blood.
Radix scrophulariae：Clearing heat and cooling blood；Nourishing Yin and falling fire；Detoxicating and resolving a mass.
Fritillaria：It is bitter, sweet, it is slightly cold.Return lung, the heart channel of Hang-Shaoyin.Dissipating bind, subsides a swelling, removing toxic substances.
The medicine of above-mentioned treatment rhinitis, the Western medicine of 0 ~ 3 kind of following parts by weight can be also added wherein：Cetirizine Hydrochloride
0.05 ~ 1, promethazine hydrochloride 0.1 ~ 1, azelastine hydrochloride 0.01 ~ 0.1.Above-mentioned three classes Western medicine is all the medicine for treating allergy, is matched somebody with somebody
Honeycomb is closed, allergic rhinitis is controlled in a short time, so as to be worked to honeycomb as buffering.
Cetirizine Hydrochloride：Cure mainly seasonality and perennially allergic rhinitis, nose conjunctivitis, nettle rash.
Promethazine hydrochloride：For various allergy（Such as asthma, nettle rash）.
Azelastine hydrochloride：For anaphylactia.
Present invention simultaneously provides the production technology of the medicine of above-mentioned treatment rhinitis, comprise the following steps：
（1）Crushed after 500 parts by weight honeycombs are freezed together with 30 ~ 100 parts by weight roots of Dahurain angelica；Crushing is conducive to improving
The dissolution rate and bioavilability of insoluble drug, are conducive to improving the dispersiveness of medicine in the formulation, are conducive to raising to have
Composition is imitated from the leaching in medicinal material, is conducive to the preparation of various preparations；
（2）The Chinese medicine of 0 ~ 6 kind of following parts by weight is added in above-mentioned mixing powder：The flower bud of lily magnolia 6 ~ 20, Radix Angelicae Sinensis 30 ~ 60, radix bupleuri 3
~ 20, stir-baked FRUCTUS GARDENIAE 10 ~ 30, radix scrophulariae 40 ~ 60, fritillaria 5 ~ 20；
（3）The Western medicine of 0 ~ 3 kind of following parts by weight is added in above-mentioned mixing powder：Cetirizine Hydrochloride 0.05 ~ 1, hydrochloric acid
Fenazil 0.1 ~ 1, azelastine hydrochloride 0.01 ~ 0.1；
（4）Pill or capsule is made in above-mentioned mixing powder.
Present invention simultaneously provides the production technology of the medicine of above-mentioned treatment rhinitis, comprise the following steps：
（1）500 parts by weight honeycombs are entered into water-filling together with 30 ~ 100 parts by weight roots of Dahurain angelica to boil 15 ~ 60 minutes；
（2）The Chinese medicine of 0 ~ 6 kind of following parts by weight is added in above-mentioned water cooking liquid：The flower bud of lily magnolia 6 ~ 20, Radix Angelicae Sinensis 30 ~ 60, radix bupleuri 3 ~
20th, stir-baked FRUCTUS GARDENIAE 10 ~ 30, radix scrophulariae 40 ~ 60, fritillaria 5 ~ 20；
（3）Water is filtered after the completion of boiling, and removes residue；
（4）The Western medicine of 0 ~ 3 kind of following parts by weight is added in above-mentioned water cooking liquid：Cetirizine Hydrochloride 0.05 ~ 1, hydrochloric acid are different
Promazine 0.1 ~ 1, azelastine hydrochloride 0.01 ~ 0.1；
（5）The propolis of 10 ~ 30 parts by weight and the beta-schardinger dextrin of 2 ~ 10 parts by weight are added in above-mentioned water cooking liquid, decocting is made
Agent, oral liquid or electuary；Honeycomb after water is boiled has part propolis loss, and supplement propolis is conducive to improving effect；And β-ring paste
Essence adds the biocompatibility of medicine, also acts the effect of sustained release as medical auxiliary materials.
Compared with prior art, advantage of the invention is that：
1. therapeutic effect is good.
2. materials are easy, cheap, nutritive value utilization rate is high.
Embodiment
With reference to embodiment, present disclosure is further illustrated.It should be appreciated that the implementation of the present invention is not limited to
In the following examples, any formal accommodation or change made to the present invention both fall within the scope of the present invention；And under
The method in embodiment is stated, is the conventional method of this area unless otherwise instructed.
Embodiment 1
Using following material：
500 grams of old honeycomb, 50 grams of the root of Dahurain angelica.
Making step：
（1）500 grams of old honeycombs and 50 grams of roots of Dahurain angelica are put into freezing crusher and crushed；
（2）0.5g pills are made in crushed mixture.
Twice, 5 pills every time, warm water takes daily one after each meal.
Embodiment 2
Using following material：
500 grams of old honeycomb, 50 grams of the root of Dahurain angelica, 12 grams of the flower bud of lily magnolia, 60 grams of Radix Angelicae Sinensis, 6 grams of radix bupleuri, 18 grams of stir-baked FRUCTUS GARDENIAE, 60 grams of radix scrophulariae, shellfish
It is female 6 grams.
Making step：
（1）500 grams of honeycombs, 50 grams of roots of Dahurain angelica, 12 grams of flower buds of lily magnolia, 60 grams of Radix Angelicae Sinensis, 6 grams of radix bupleuri, 18 are added in 2500 milliliters of water
Gram stir-baked FRUCTUS GARDENIAE, 60 grams of radix scrophulariaes and 6 grams of fritillaria water are boiled 30 minutes；
（2）Water is filtered after the completion of boiling, and removes residue；
（3）20 grams of propolis and 5 grams of beta-schardinger dextrins are added in water cooking liquid, aliquot, every part 50 milli are distributed into after being well mixed
Rise, be placed in refrigerator cold-storage preservation.
It is taken twice daily, each taking portion, is taken after warm water heating.
Embodiment 3
Using following material：
500 grams of old honeycomb, 50 grams of the root of Dahurain angelica, 1 gram of Cetirizine Hydrochloride.
Making step：
（1）500 grams of old honeycombs and 50 grams of roots of Dahurain angelica are put into freezing crusher and crushed；
（2）1 gram of Cetirizine Hydrochloride is mixed with said mixture；
（3）0.5g pills are made in crushed mixture.
Twice, 5 pills every time, warm water takes daily one after each meal.
Embodiment 4
Using following material：
500 grams of old honeycomb, 50 grams of the root of Dahurain angelica, 12 grams of the flower bud of lily magnolia, 60 grams of Radix Angelicae Sinensis, 6 grams of radix bupleuri, 18 grams of stir-baked FRUCTUS GARDENIAE, 60 grams of radix scrophulariae, shellfish
Female 6 grams, 1 gram of Cetirizine Hydrochloride.
Making step：
（1）500 grams of honeycombs, 50 grams of roots of Dahurain angelica, 12 grams of flower buds of lily magnolia, 60 grams of Radix Angelicae Sinensis, 6 grams of radix bupleuri, 18 are added in 2500 milliliters of water
Gram stir-baked FRUCTUS GARDENIAE, 60 grams of radix scrophulariaes and 6 grams of fritillaria water are boiled 30 minutes；
（2）Water is filtered after the completion of boiling, and removes residue；
（3）1 gram of Cetirizine Hydrochloride, 20 grams of propolis and 5 grams of beta-schardinger dextrins are added in water cooking liquid, are dispensed after being well mixed
Into aliquot, 50 milliliters every part, refrigerator cold-storage preservation is placed in.
It is taken twice daily, each taking portion, is taken after warm water heating.
Comparative example 1
Old honeycomb directly chews clothes, twice a day, each 50g.
Comparative example 2
" taking deep soup " is formulated, 6 grams of the flower bud of lily magnolia, 30 grams of Radix Angelicae Sinensis, 3 grams of radix bupleuri, 9 grams of stir-baked FRUCTUS GARDENIAE, 30 grams of radix scrophulariae, 3 grams of fritillaria, decocting
Clothes.
Comparative example 3
Cetirizine hydrochloride Tablets, once a day, each 10mg.
The Chinese medicine preparation of the present invention can effectively treat rhinitis, by the clinical treatment of 2 years multipair 147 rhinitis patients, take
Preferable curative effect was obtained, was a course for the treatment of with 3 months, fully recover patient 120, effective patient 21, invalid patient 6, effectively
Rate is shown in Table 1 up to 100%.
Evaluation criteria：
1st, fully recover：Rhinitis Symptoms are wholly absent in the course for the treatment of, and are not recurred in half a year；
2nd, it is effective：Rhinitis Symptoms disappear in the course for the treatment of, there is slight recurrence after drug withdrawal；
3rd, it is invalid：Rhinitis Symptoms are not eased.
Table 1：
| Case | Recovery from illness | It is effective | It is invalid | It is efficient（%） | |
| Embodiment 1 | 33 | 20 | 11 | 2 | 93.94% |
| Embodiment 2 | 38 | 34 | 2 | 2 | 94.74% |
| Embodiment 3 | 22 | 16 | 4 | 2 | 90.91% |
| Embodiment 4 | 54 | 50 | 4 | 0 | 100% |
| Comparative example 1 | 80%（Data source is in document and report） | ||||
| Comparative example 2 | 91.67%（Data source is in document and report） | ||||
| Comparative example 3 | It is only capable of controlling allergic symptom in short term |
Claims (1)
1. a kind of medicine for treating rhinitis, it is characterised in that use following material：500 grams of old honeycomb, 50 grams of the root of Dahurain angelica, the flower bud of lily magnolia 12
Gram, 60 grams of Radix Angelicae Sinensis, 6 grams of radix bupleuri, 18 grams of stir-baked FRUCTUS GARDENIAE, 60 grams of radix scrophulariae, 6 grams of fritillaria, 1 gram of Cetirizine Hydrochloride；
The making step of the medicine is as follows：
(1) 500 grams of honeycombs, 50 grams of roots of Dahurain angelica, 12 grams of flower buds of lily magnolia, 60 grams of Radix Angelicae Sinensis, 6 grams of radix bupleuri, 18 grams of stir-frys are added in 2500 milliliters of water
Cape jasmine, 60 grams of radix scrophulariaes and 6 grams of fritillaria water are boiled 30 minutes；
(2) filtered after the completion of water is boiled, remove residue；
(3) 1 gram of Cetirizine Hydrochloride, 20 grams of propolis and 5 grams of beta-schardinger dextrins are added in water cooking liquid, are distributed into after being well mixed small
Part, 50 milliliters every part, it is placed in refrigerator cold-storage preservation.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410319819.4A CN104622924B (en) | 2014-07-08 | 2014-07-08 | A kind of medicine and its production technology for treating rhinitis |
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| CN201410319819.4A CN104622924B (en) | 2014-07-08 | 2014-07-08 | A kind of medicine and its production technology for treating rhinitis |
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| CN104622924B true CN104622924B (en) | 2017-10-24 |
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| CN106540051B (en) * | 2016-11-30 | 2018-07-24 | 谭智成 | Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110159A (en) * | 1994-04-12 | 1995-10-18 | 曹志刚 | Biyanan medicine for curing rhinitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20050084725A (en) * | 2004-02-24 | 2005-08-29 | 학교법인 영남학원 | Composition comprising an extract of anthriscus sylvesstris for prevention and treatment of inflammatory or allergy diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110159A (en) * | 1994-04-12 | 1995-10-18 | 曹志刚 | Biyanan medicine for curing rhinitis |
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