CN106540051B - Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis - Google Patents
Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis Download PDFInfo
- Publication number
- CN106540051B CN106540051B CN201611077342.9A CN201611077342A CN106540051B CN 106540051 B CN106540051 B CN 106540051B CN 201611077342 A CN201611077342 A CN 201611077342A CN 106540051 B CN106540051 B CN 106540051B
- Authority
- CN
- China
- Prior art keywords
- parts
- rhinitis
- pulvis
- treatment
- garlic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010039083 rhinitis Diseases 0.000 title claims abstract description 68
- 239000003814 drug Substances 0.000 title claims abstract description 40
- 239000000203 mixture Substances 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title claims description 14
- 240000002234 Allium sativum Species 0.000 claims abstract description 36
- 235000004611 garlic Nutrition 0.000 claims abstract description 36
- 241001251949 Xanthium sibiricum Species 0.000 claims abstract description 29
- 244000246386 Mentha pulegium Species 0.000 claims abstract description 28
- 235000016257 Mentha pulegium Nutrition 0.000 claims abstract description 28
- 235000004357 Mentha x piperita Nutrition 0.000 claims abstract description 28
- 235000001050 hortel pimenta Nutrition 0.000 claims abstract description 28
- 241000928504 Centipeda minima Species 0.000 claims abstract description 26
- 239000009636 Huang Qi Substances 0.000 claims abstract description 20
- 241000218394 Magnolia liliiflora Species 0.000 claims abstract description 19
- 241000758794 Asarum Species 0.000 claims abstract description 18
- 244000247747 Coptis groenlandica Species 0.000 claims abstract description 17
- 235000002991 Coptis groenlandica Nutrition 0.000 claims abstract description 17
- 235000001287 Guettarda speciosa Nutrition 0.000 claims abstract description 13
- 239000000843 powder Substances 0.000 claims description 31
- 239000002994 raw material Substances 0.000 claims description 24
- 239000002245 particle Substances 0.000 claims description 23
- 229940079593 drug Drugs 0.000 claims description 16
- 238000002156 mixing Methods 0.000 claims description 16
- 238000001035 drying Methods 0.000 claims description 12
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000008159 sesame oil Substances 0.000 claims description 5
- 235000011803 sesame oil Nutrition 0.000 claims description 5
- 229940099259 vaseline Drugs 0.000 claims description 5
- 241000264877 Hippospongia communis Species 0.000 claims description 4
- 235000012907 honey Nutrition 0.000 claims description 4
- 240000002045 Guettarda speciosa Species 0.000 claims 4
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims 1
- 229940047670 sodium acrylate Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 15
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 241000628997 Flos Species 0.000 description 9
- 208000002193 Pain Diseases 0.000 description 9
- 201000010099 disease Diseases 0.000 description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 9
- 210000001331 nose Anatomy 0.000 description 9
- 241000125175 Angelica Species 0.000 description 8
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 8
- 239000003651 drinking water Substances 0.000 description 7
- 235000020188 drinking water Nutrition 0.000 description 7
- 206010019233 Headaches Diseases 0.000 description 6
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 6
- 231100000869 headache Toxicity 0.000 description 6
- 210000002850 nasal mucosa Anatomy 0.000 description 6
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 5
- 238000000227 grinding Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 210000003928 nasal cavity Anatomy 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 229910001220 stainless steel Inorganic materials 0.000 description 5
- 239000010935 stainless steel Substances 0.000 description 5
- 239000000835 fiber Substances 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 241000213006 Angelica dahurica Species 0.000 description 3
- 208000006820 Arthralgia Diseases 0.000 description 3
- 206010011224 Cough Diseases 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 208000001780 epistaxis Diseases 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 201000002266 mite infestation Diseases 0.000 description 3
- 239000002674 ointment Substances 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 206010028735 Nasal congestion Diseases 0.000 description 2
- 206010028748 Nasal obstruction Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 206010067171 Regurgitation Diseases 0.000 description 2
- 206010039085 Rhinitis allergic Diseases 0.000 description 2
- 208000036071 Rhinorrhea Diseases 0.000 description 2
- 206010039101 Rhinorrhoea Diseases 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 206010047139 Vasoconstriction Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 201000010105 allergic rhinitis Diseases 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000003712 anti-aging effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000006837 decompression Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 230000036737 immune function Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 2
- 230000035882 stress Effects 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000004371 toothache Diseases 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 230000025033 vasoconstriction Effects 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010001076 Acute sinusitis Diseases 0.000 description 1
- 206010001580 Albuminuria Diseases 0.000 description 1
- 244000210247 Angelica laevis Species 0.000 description 1
- 241000272814 Anser sp. Species 0.000 description 1
- 241000228197 Aspergillus flavus Species 0.000 description 1
- 241001225321 Aspergillus fumigatus Species 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 208000019838 Blood disease Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 241000521257 Hydrops Species 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 240000007049 Juglans regia Species 0.000 description 1
- 235000009496 Juglans regia Nutrition 0.000 description 1
- 241000427250 Moehringia Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 241000588767 Proteus vulgaris Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000004680 Rectal Fistula Diseases 0.000 description 1
- 241000607768 Shigella Species 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 244000061458 Solanum melongena Species 0.000 description 1
- 235000002597 Solanum melongena Nutrition 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 206010044684 Trismus Diseases 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 206010002156 anal fistula Diseases 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 229910052785 arsenic Inorganic materials 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 229940091771 aspergillus fumigatus Drugs 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000032677 cell aging Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 201000009151 chronic rhinitis Diseases 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 description 1
- 230000009849 deactivation Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 229960002179 ephedrine Drugs 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 208000014951 hematologic disease Diseases 0.000 description 1
- 208000018706 hematopoietic system disease Diseases 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 208000002672 hepatitis B Diseases 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000001969 hypertrophic effect Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 230000001114 myogenic effect Effects 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- IAIWVQXQOWNYOU-FPYGCLRLSA-N nitrofural Chemical group NC(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 IAIWVQXQOWNYOU-FPYGCLRLSA-N 0.000 description 1
- 229960001907 nitrofurazone Drugs 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000003910 polypeptide antibiotic agent Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 230000004905 short-term response Effects 0.000 description 1
- 208000027765 speech disease Diseases 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 235000020234 walnut Nutrition 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Insects & Arthropods (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese medicine for treating rhinitis composition, the Chinese medicine composition includes following component by weight:1.5~3 parts of 12~16 parts of Centipeda minima, 3~6 parts of Siberian cocklebur, 7~9 parts of the flower bud of lily magnolia, 0.5~2 part of fructus gleditsiae, 0.5~2 part of the coptis, 0.5~2 part of asarum, 0.5~2 part of honeycomb, 1.5~3 parts of peppermint, 1~3 part windproof, 1~3 part of the root of Dahurain angelica, 1~3 part of Radix Astragali and only son's garlic.In addition, the invention also discloses pulvis and paste containing the Chinese medicine composition, pulvis or paste disclosed in this invention, when for treating rhinitis, short treating period is quick, and cure rate is high, and has no toxic side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine for treating rhinitis, especially treat rhinitis Chinese medicine composition, pulvis and paste and
Preparation method.
Background technology
Rhinitis is a kind of common disease in China, accounts for crowd's ratio up to 10%, in big, moist, the cold area morbidity of the temperature difference
Rate is very high, it normally lives to patient and causes serious puzzlement.Currently, the method for the treatment of rhinitis, mainly takes orally, controls outside.
Endo-medicine long-time service has various side effects;Outer drug of controlling is mainly the blood vessel absorption that husband blocks that numb drops is representative
Agent, although quick, there is no the basic for the treatment of to rhinitis, and drug withdrawal will recur, and administration time is long, can also form drug resistance
Property.
Invention content
Based on this, provided it is an object of the invention to overcome in place of above-mentioned the deficiencies in the prior art it is a kind of without side-effects,
The drug of the high treatment rhinitis of cure rate.
To achieve the above object, the technical solution that the present invention takes is:A kind of Chinese medicine for treating rhinitis composition, including with
Under component by weight:12~16 parts of Centipeda minima, 3~6 parts of Siberian cocklebur, 7~9 parts of the flower bud of lily magnolia, 0.5~2 part of fructus gleditsiae, the coptis
0.5~2 part, 0.5~2 part of asarum, 0.5~2 part of honeycomb, 1.5~3 parts of peppermint, 1~3 part windproof, 1~3 part of the root of Dahurain angelica, Radix Astragali 1~
3 parts and 1.5~3 parts of only son's garlic.
《Compendium of Materia Medica》It records:" food grass in goose, above reaches brains, and controls top pain mesh disease, leads to nose gas and falls flat meat;It is interior to reach lung
Through and control phlegm malaria, dissipate sore swells;It removes the work(of screen, especially aobvious wonderful." Centipeda minima in the present invention cures mainly anemofrigid headache, phlegm of coughing
It is more, obstructed, nasosinusitis runny nose of having a stuffy nose;
The fruit of the achene of Siberian cocklebur in the present invention has effects that wet relieve heat, clearing the nasal passage, analgesic desinsection, can be used for chill head
Bitterly, the treatment of nasal congestion, dentalgia, wind-cold-dampness arthralgia, four limbs contraction pain, mange, itch;Modern medical experiment finds that Siberian cocklebur is treated
Rhinitis chronic effective percentage also has acute rhinosinusitis certain effect 50% or more;
The flower bud of lily magnolia has the effect of dispersing wind and cold, can be used for controlling rhinitis, blood pressure lowering;Fructus gleditsiae cures mainly sensible, washs phlegm, searches wind, desinsection,
《Detailed outline》Fructus gleditsiae is recorded to cure mainly:Logical lung and large intestine gas, control throat numbness plug, mental disorder is breathed with cough, wind pestilence, mange;
The coptis has the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating, is used for damp and hot feeling of fullness, vomits acid regurgitation, rush down dysentery, jaundice, high fever god
Dusk, heart-fire hyperactivity, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells furunculosis;Eczema, wet sore are controlled outside, duct is suppurated,
And it is mutually tied for fever and chills, damp and hot middle resistance, feeling of fullness vomiting;
Asarum, major function relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping is sensible, warming lung and resolving fluid, is used for anemofrigid cold, has a headache, toothache,
Nasal congestion, allergic rhinitis, nasosinusitis, arthralgia pain due to rheumatism, sputum cough, asarum is as medicinal plant, Shi Zai Qin Han《Sheng Nong's herbal classic》,
《Sheng Nong's herbal classic》It is classified as top grade;
Honeycomb medical value is also very high, and the honeycomb for commonly using fresh clean treats rhinitis;New honeycomb also has treatment hepatitis, nose
The effect of diseases such as scorching and rheumatic arthritis.Studies have shown that honeycomb preparation plays the role of promoting Immune Function, bee
Nest immersion liquid both had deactivation to hepatitis B surface antibody, also to staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, dysentery
Shigella, typhoid bacillus and proteus vulgaris etc. have very strong restraint;To aspergillus fumigatus, aspergillus flavus, eggplant sickle bacterium, a bright beading
The fungies such as bacterium also have inhibiting effect;
Peppermint is one of Chinese conventional Chinese medicine, for treating pungent cool property sweating antipyretic medicine, controls influenza, headache, mesh
The diseases such as red, body is warm, the swelling and pain of throat, gum;External application can control neuralgia, pruitus, fash and eczema etc.;Usually with peppermint generation
Tea, clear away heart-fire improving eyesight;It is windproof, be used for diseases caused by external factors exterior syndrome, rubella itch, arthralgia pain due to rheumatism, lockjaw just, the insufficiency of the spleen with overabundance of dampness;
Root of Dahurain angelica major function wind-dispelling, eliminating dampness are subsided a swelling, analgesic;Control headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines
Wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, mange;《Detailed outline》There is speech:The root of Dahurain angelica, the white acrid flavour of color, row hand sun are bright;It is warm-natured
Gas is thick, and row foot sun is bright;It is reached on fragrance, enters lung meridian;Such as head, mesh, eyebrow, all diseases of tooth, three through wind-heat;Such as leakage, band, carbuncle
The all diseases of subcutaneous ulcer, three through it is damp and hot;Wind-heat person is pungent to dissipate it, and damp and hot person's temperature is to remove it;For the bright main ingredient of sun, therefore blood disease, tire can be controlled again
Disease, and apocenosis myogenic pain relieving;It can control nasosinusitis, nosebleed epistaxis, dentalgia, pain in the supra-orbital bone, and big intestines wind is secret, bleeding urine, and married woman's blood wind is dizzy
Fortune, regurgitation spit food;Solve arsenic poison, snakebite, knife arrow metal-inflicted wound;
The medicinal of Radix Astragali has more than 2000 years history so far, there is enhancing body's immunity, liver protection, diuresis, anti-ageing
Always, resisting stress, decompression and wide antibacterial action;Modern medicine study shows that Radix Astragali has enhancing body's immunity, protects
Liver, diuresis, anti-aging, resisting stress, decompression and wide antibacterial action;Jishengshenqiwan albuminuria, enhancing cardiac muscle can be eliminated
Convergent force adjusts blood-sugar content;Radix Astragali can not only coronary artery dilator, improve myocardial blood supply, improve immune function, and can
The process of delaying cell aging;Radix Astragali is convenient, can decoction, soft extracts, infusing drugs in wine enters dish etc.;
The size of only son's garlic is similar with walnut kernel, has the smell of garlic, but without so strong;General garlic is divided into more
Valve, but only son's garlic only has a valve;Contained garlic essence is more in only son's garlic score valve garlic, and garlic essence has wide effect bactericidal effect, meanwhile, garlic
Essence is a kind of antioxidant, and the effect of the anti-cell degeneration of anticancer (mutation) of garlic essence is right mainly from its antioxidation
Have in the free radical that peroxide generates and neutralizes elimination effect.
Preferably, the Chinese medicine composition includes following component by weight:13~15 parts of Centipeda minima, Siberian cocklebur 4~5
Part, 3 parts of the flower bud of lily magnolia, 1 part of fructus gleditsiae, 1 part of the coptis, 1 part of asarum, 1 part of honeycomb, 2 parts of peppermint, 2 parts windproof, 2 parts of the root of Dahurain angelica, 2 parts of Radix Astragali,
With 2 parts of only son's garlic.Present inventor by test of many times find, when Chinese medicine composition use raw material proportioning for:Sandwort
It is 14 parts of grass, 4.5 parts of Siberian cocklebur, 8 parts of the flower bud of lily magnolia, 1 part of fructus gleditsiae, 1 part of the coptis, 1 part of asarum, 1 part of honeycomb, 2 parts of peppermint, 2 parts windproof, white
When 2 parts of the root of Dahurian angelica, 2 parts of Radix Astragali, 2 parts of only son's garlic, the rhinitis cure rate of pulvis or paste prepared therefrom reaches highest.
Meanwhile the present invention also provides a kind of pulvis for treating rhinitis comprising made of above-mentioned Chinese medicine composition
Dry powder.
Preferably, the dry powder is the particle powder of 200 mesh or more.
Preferably, the mass percentage of water is 10% or less in the pulvis.
As another aspect of the present invention, the present invention also provides a kind of paste for treating rhinitis comprising above-mentioned pulvis
And excipient.
Preferably, the excipient includes at least one of honey, vaseline, Sodium Polyacrylate, sesame oil.
As another aspect of the present invention, the present invention also provides a kind of preparation methods of pulvis that treating rhinitis, including
Following steps:
(1) following raw material is weighed:It is Centipeda minima, Siberian cocklebur, the flower bud of lily magnolia, fructus gleditsiae, the coptis, asarum, honeycomb, peppermint, windproof, white
The root of Dahurian angelica, Radix Astragali and only son's garlic;
(2) by after the raw material drying in step (1), it is milled to particle powder;
(3) fresh Centipeda minima, Siberian cocklebur, Flos Magnoliae Liliflorae, peppermint and only son's garlic are cleaned, concoction is squeezed into respectively, then mixes
Concoction must be mixed;
(4) mixing concoction will mix obtained by particle powder and step (3) obtained by step (2), it is dry later, sterilize to get to
Treat the pulvis of rhinitis.
Preferably, fresh Centipeda minima, Siberian cocklebur, Flos Magnoliae Liliflorae, peppermint and only son's garlic are used through ozone in the step (3)
The drinking water of processing cleans;It is highly preferred that the fresh Centipeda minima, Siberian cocklebur, Flos Magnoliae Liliflorae, peppermint and only son's garlic are used through smelly
After the drinking water cleaning of oxygen processing, concoction is squeezed into respectively;More preferably, in the step (2) particle Powder Particle Size be 200 mesh with
On;It is highly preferred that the mass percentage of water is 10% or less in particle powder in the step (2).
Meanwhile the present invention also provides a kind of preparation method of paste that treating rhinitis, including the following steps:
(1) following raw material is weighed:It is Centipeda minima, Siberian cocklebur, the flower bud of lily magnolia, fructus gleditsiae, the coptis, asarum, honeycomb, peppermint, windproof, white
The root of Dahurian angelica, Radix Astragali and only son's garlic;
(2) by after the raw material drying in step (1), it is milled to particle powder;
(3) fresh Centipeda minima, Siberian cocklebur, Flos Magnoliae Liliflorae, peppermint and only son's garlic are cleaned, concoction is squeezed into respectively, then mixes
Concoction must be mixed;
(4) mixing concoction obtained by particle powder obtained by step (2) and step (3) is mixed, drying later sterilizes, and must treat
The pulvis of rhinitis;
(5) pulvis for the treatment of rhinitis obtained by step (4) is mixed with excipient to get the paste for the treatment of rhinitis.
In addition, the application the present invention also provides above-mentioned Chinese medicine composition in the drug for preparing treatment rhinitis.It should
Illustrate, the rhinitis is allergic rhinitis, chronic simple rhinitis, nasosinusitis or chronic hypertrophic rhinitis.
Compared with the existing technology, beneficial effects of the present invention are:
(1) pulvis of the invention is more easy to be absorbed by nasal mucosa, and short treating period is quick, high efficiency;
(2) hydrops in nasal cavity can be discharged in pulvis of the invention, have effects that the promoting flow of qi and blood circulation, anti-inflammatory, repair schneiderian membrance;
(3) medicament and paste medicine action time of the invention are controllable, nontoxic, without side-effects.
Specific implementation mode
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1
A kind of preparation method of pulvis that treating rhinitis, includes the following steps:
(1) raw material of following parts by weight is weighed:6 parts of Centipeda minima, 1 part of Siberian cocklebur, 2 parts of the flower bud of lily magnolia, 2 parts of fructus gleditsiae, the coptis 0.5
Part, 1 part of asarum, 1 part of honeycomb, 2 parts of peppermint, 1 part windproof, 3 parts of the root of Dahurain angelica, 1 part of Radix Astragali, 2 parts of only son's garlic;
(2) by raw material drying in step (1) to water content 10%, the particle powder of 200 mesh is milled to superfine mill;
(3) 10 parts of fresh Centipeda minima, 2 parts of Siberian cocklebur, 5 parts of Flos Magnoliae Liliflorae, 1 part of peppermint are cleaned with drinking water treated by ozone
It with 1 part of only son's garlic, uses stainless steel juice extractor to squeeze into concoction respectively, then mixes to obtain mixing concoction;
(4) mixing concoction will mix obtained by particle powder and step (3) obtained by step (2), it is dry later, sterilize to get to
Treat the pulvis of rhinitis.
The pulvis of above-mentioned treatment rhinitis is mixed with excipient honey, you can the rhinitis ointment for facilitating patient to use is made.
The present embodiment raw material is easy to get, at low cost, easy to use, makes simply, drug solubility is significantly larger than common medicinal powder, together
When ultra-fine grinding be more easy to be absorbed by nasal mucosa, short treating period is quick, and the ineffective trouble of drug for treating rhinitis is taken orally to being used for a long time
Person, general half an hour can alleviate discomfort.
Embodiment 2
A kind of preparation method of pulvis that treating rhinitis, includes the following steps:
(1) raw material of following parts by weight is weighed:2 parts of Centipeda minima, 4 parts of Siberian cocklebur, 4 parts of the flower bud of lily magnolia, 0.5 part of fructus gleditsiae, the coptis 2
Part, 1 part of asarum, 1 part of honeycomb, 0.5 part of peppermint, 3 parts windproof, 1 part of the root of Dahurain angelica, 3 parts of Radix Astragali, 0.5 part of only son's garlic;
(2) by raw material drying in step (1) to water content 9%, the particle powder of 220 mesh is milled to superfine mill;
(3) 10 parts of fresh Centipeda minima, 2 parts of Siberian cocklebur, 5 parts of Flos Magnoliae Liliflorae, 1 part of peppermint are cleaned with drinking water treated by ozone
It with 1 part of only son's garlic, uses stainless steel juice extractor to squeeze into concoction respectively, then mixes to obtain mixing concoction;
(4) mixing concoction will mix obtained by particle powder and step (3) obtained by step (2), it is dry later, sterilize to get to
Treat the pulvis of rhinitis.
The pulvis of above-mentioned treatment rhinitis is mixed with excipient vaseline, you can the rhinitis ointment for facilitating patient to use is made.
The present embodiment raw material is easy to get, at low cost, easy to use, makes simply, drug solubility is significantly larger than common medicinal powder, together
When ultra-fine grinding be more easy to be absorbed by nasal mucosa, short treating period is quick, and the ineffective trouble of drug for treating rhinitis is taken orally to being used for a long time
Person, general half an hour can alleviate discomfort.
Embodiment 3
A kind of preparation method of pulvis that treating rhinitis, includes the following steps:
(1) raw material of following parts by weight is weighed:5 parts of Centipeda minima, 2 parts of Siberian cocklebur, 2 parts of the flower bud of lily magnolia, 1 part of fructus gleditsiae, the coptis 1
Part, 2 parts of asarum, 0.5 part of honeycomb, 1 part of peppermint, 2 parts windproof, 2.5 parts of the root of Dahurain angelica, 1 part of Radix Astragali, 1.5 parts of only son's garlic;
(2) by raw material drying in step (1) to water content 7%, the particle powder of 230 mesh is milled to superfine mill;
(3) 10 parts of fresh Centipeda minima, 2 parts of Siberian cocklebur, 5 parts of Flos Magnoliae Liliflorae, 1 part of peppermint are cleaned with drinking water treated by ozone
It with 1 part of only son's garlic, uses stainless steel juice extractor to squeeze into concoction respectively, then mixes to obtain mixing concoction;
(4) mixing concoction will mix obtained by particle powder and step (3) obtained by step (2), it is dry later, sterilize to get to
Treat the pulvis of rhinitis.
The pulvis of above-mentioned treatment rhinitis is mixed with excipient vaseline and sesame oil, you can the nose for facilitating patient to use is made
Scorching cream.
The present embodiment raw material is easy to get, at low cost, easy to use, makes simply, drug solubility is significantly larger than common medicinal powder, together
When ultra-fine grinding be more easy to be absorbed by nasal mucosa, short treating period is quick, and the ineffective trouble of drug for treating rhinitis is taken orally to being used for a long time
Person, general half an hour can alleviate discomfort.
Embodiment 4
A kind of preparation method of pulvis that treating rhinitis, includes the following steps:
(1) raw material of following parts by weight is weighed:3 parts of Centipeda minima, 3 parts of Siberian cocklebur, 4 parts of the flower bud of lily magnolia, 1 part of fructus gleditsiae, the coptis 1
Part, 0.5 part of asarum, 2 parts of honeycomb, 1 part of peppermint, 2.5 parts windproof, 2 parts of the root of Dahurain angelica, 2 parts of Radix Astragali, 1 part of only son's garlic;
(2) by raw material drying in step (1) to water content 5%, the particle powder of 240 mesh is milled to superfine mill;
(3) 10 parts of fresh Centipeda minima, 2 parts of Siberian cocklebur, 5 parts of Flos Magnoliae Liliflorae, 1 part of peppermint are cleaned with drinking water treated by ozone
It with 1 part of only son's garlic, uses stainless steel juice extractor to squeeze into concoction respectively, then mixes to obtain mixing concoction;
(4) mixing concoction will mix obtained by particle powder and step (3) obtained by step (2), it is dry later, sterilize to get to
Treat the pulvis of rhinitis.
The pulvis of above-mentioned treatment rhinitis is mixed with excipient vaseline, Sodium Polyacrylate and sesame oil, you can be made conveniently
The rhinitis ointment that patient uses.
The present embodiment raw material is easy to get, at low cost, easy to use, makes simply, drug solubility is significantly larger than common medicinal powder, together
When ultra-fine grinding be more easy to be absorbed by nasal mucosa, short treating period is quick, and the ineffective trouble of drug for treating rhinitis is taken orally to being used for a long time
Person, general half an hour can alleviate discomfort.
Embodiment 5
A kind of preparation method for treating rhinitis pulvis, includes the following steps:
(1) raw material of following parts by weight is weighed:4 parts of Centipeda minima, 2.5 parts of Siberian cocklebur, 3 parts of the flower bud of lily magnolia, 1 part of fructus gleditsiae, the coptis 1
Part, 1 part of asarum, 1 part of honeycomb, 1 part of peppermint, 2 parts windproof, 2 parts of the root of Dahurain angelica, 2 parts of Radix Astragali, 1 part of only son's garlic;
(2) by raw material drying in step (1) to water content 3%, the particle powder of 260 mesh is milled to superfine mill;
(3) 10 parts of fresh Centipeda minima, 2 parts of Siberian cocklebur, 5 parts of Flos Magnoliae Liliflorae, 1 part of peppermint are cleaned with drinking water treated by ozone
It with 1 part of only son's garlic, uses stainless steel juice extractor to squeeze into concoction respectively, then mixes to obtain mixing concoction;
(4) mixing concoction will mix obtained by particle powder and step (3) obtained by step (2), it is dry later, sterilize to get to
Treat the pulvis of rhinitis.
The pulvis of above-mentioned treatment rhinitis is mixed with excipient honey and sesame oil, you can the rhinitis for facilitating patient to use is made
Cream.
The present embodiment raw material is easy to get, at low cost, easy to use, makes simply, drug solubility is significantly larger than common medicinal powder, together
When ultra-fine grinding be more easy to be absorbed by nasal mucosa, short treating period is quick, and the ineffective trouble of drug for treating rhinitis is taken orally to being used for a long time
Person, general half an hour can alleviate discomfort.
The pulvis of 6 present invention of embodiment and existing drug therapy patients with rhinitis contrast test
Therapy:The pulvis obtained by embodiment 1-5 is respectively adopted as medicine, sprays every time into nasal cavity
100mg, it is each primary daily morning and evening;Using the medicine as a control group of the clear nose liquid of furan fiber crops in the market, sprayed every time into nasal cavity
Furan fiber crops clear nose liquid 150mg, it is each primary daily morning and evening.It was primary with 7 days, 4 times as a treatment course, treats 2 courses for the treatment of respectively.
Treatment object:210 outpatient service patients with rhinitis, wherein male 118, women 92, age distribution was at 15~60 years old
Between, the course of disease 9 months~15 years;210 patients with rhinitis are randomly divided into 6 groups, every group of 35 people.Cardinal symptom is:It is intermittent or
Alternately have a stuffy nose;Due to nasal obstruction, or have hyposphresia, headache, giddy, speak in symptoms such as rhinolalia clausas;More tears, Chang Wei
Mucus or glutinous purulence, majority have headache, loss of appetite, easily tired, failure of memory and insomnia;Nasal decongestion, concha
It is loose.
Treatment standard:Recovery from illness, symptom all disappear, and nasal cavity checks normal;Effectively, nasal obstruction, runny nose symptom mitigate, local volume
Sign improves.
Treatment results:As shown in the table.
| Project | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | Control group |
| Patient populations | 35 | 35 | 35 | 35 | 35 | 35 |
| Recovery from illness number | 31 | 31 | 32 | 32 | 34 | 13 |
| Cure rate | 88.6% | 88.6% | 91.4% | 91.4% | 97.1% | 37.1% |
| Efficiently individual quantity | 34 | 34 | 35 | 35 | 35 | 28 |
| It is efficient | 97.1% | 97.1% | 100% | 100% | 100% | 80% |
The clear nose liquid of furan fiber crops is one of the representative of external remedy for treating rhinitis currently on the market, and main component is nitrofurazone and hydrochloric acid
Ephedrine, action principle is vasoconstriction, anti-inflammatory, although short-term response is fast, there is no nasal cavity tissue is repaired, is breathed in reinforcing
The function of road qi and blood, long-time service have side effect.And the present invention uses pure Chinese medicinal preparation, using the cold vasoconstriction of the coptis,
Natural antibacterial peptide anti-inflammatory in honeycomb, while adding that the Chinese medicines such as the flower bud of lily magnolia, Radix Astragali, Siberian cocklebur, asarum are sensible, enrich blood, promoting the circulation of qi, reach and disappears
Swollen, sterilization, promoting the circulation of qi, promoting blood circulation, dredging collateral effect, with therapeutic efficiency that is multi-pronged, getting twice the result with half the effort, as can be seen from the above table,
The pulvis therapeutic effect of the present invention is far superior to the clear nose liquid of furan fiber crops.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than is protected to the present invention
The limitation of range is protected, although being explained in detail to the present invention with reference to preferred embodiment, those skilled in the art should
Understand, technical scheme of the present invention can be modified or replaced equivalently, without departing from the essence of technical solution of the present invention
And range.
Claims (10)
1. a kind of Chinese medicine for treating rhinitis composition, which is characterized in that be grouped as by the group of following parts by weight:Centipeda minima 12~
16 parts, 3~6 parts of Siberian cocklebur, 7~9 parts of the flower bud of lily magnolia, 0.5~2 part of fructus gleditsiae, 0.5~2 part of the coptis, 0.5~2 part of asarum, honeycomb 0.5~
1.5 ~ 3 parts of 2 parts, 1.5~3 parts of peppermint, 1~3 part windproof, 1~3 part of the root of Dahurain angelica, 1~3 part of Radix Astragali and only son's garlic.
2. the Chinese medicine composition for the treatment of rhinitis according to claim 1, which is characterized in that be grouped by the group of following parts by weight
At:13~15 parts of Centipeda minima, 4~5 parts of Siberian cocklebur, 8 parts of the flower bud of lily magnolia, 1 part of fructus gleditsiae, 1 part of the coptis, 1 part of asarum, 1 part of honeycomb, peppermint
2 parts of 2 parts, 2 parts windproof, 2 parts of the root of Dahurain angelica, 2 parts of Radix Astragali and only son's garlic.
3. a kind of pulvis for treating rhinitis, which is characterized in that including made of Chinese medicine composition as claimed in claim 1 or 2
Dry powder.
4. the pulvis for the treatment of rhinitis according to claim 3, which is characterized in that the dry powder is the particle of 200 mesh or more
Powder.
5. the pulvis for the treatment of rhinitis according to claim 3 or 4, which is characterized in that the quality percentage of water in the pulvis
Content is 10% or less.
6. a kind of paste for treating rhinitis, which is characterized in that include the pulvis and excipient as described in claim 3-5 is any.
7. the paste for the treatment of rhinitis according to claim 6, which is characterized in that the excipient is honey, vaseline, gathers
At least one of sodium acrylate, sesame oil.
8. it is a kind of as described in 5 any one of claim 3  ̄ treat rhinitis pulvis preparation method, which is characterized in that including with
Lower step:
(1) following raw material is weighed:Centipeda minima, Siberian cocklebur, the flower bud of lily magnolia, fructus gleditsiae, the coptis, asarum, honeycomb, peppermint, the windproof, root of Dahurain angelica,
Radix Astragali and only son's garlic;
(2) by after the raw material drying in step (1), it is milled to particle powder;
(3) fresh Centipeda minima, Siberian cocklebur, the flower bud of lily magnolia, peppermint and only son's garlic are cleaned, squeezes into concoction respectively, then mixes to obtain mixing
Concoction;
(4) it mixing concoction will mix obtained by particle powder and step (3) obtained by step (2), it is dry later, sterilize to get to treatment
The pulvis of rhinitis.
9. a kind of preparation method of the paste of the rhinitis for the treatment of as claimed in claims 6 or 7, which is characterized in that include the following steps:
(1) following raw material is weighed:Centipeda minima, Siberian cocklebur, the flower bud of lily magnolia, fructus gleditsiae, the coptis, asarum, honeycomb, peppermint, the windproof, root of Dahurain angelica,
Radix Astragali and only son's garlic;
(2) by after the raw material drying in step (1), it is milled to particle powder;
(3) fresh Centipeda minima, Siberian cocklebur, the flower bud of lily magnolia, peppermint and only son's garlic are cleaned, squeezes into concoction respectively, then mixes to obtain mixing
Concoction;
(4) mixing concoction obtained by particle powder obtained by step (2) and step (3) is mixed, drying later sterilizes, and obtains treatment rhinitis
Pulvis;
(5) pulvis for the treatment of rhinitis obtained by step (4) is mixed with excipient to get the paste for the treatment of rhinitis.
10. a kind of application of Chinese medicine composition as claimed in claim 1 or 2 in the drug for preparing treatment rhinitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611077342.9A CN106540051B (en) | 2016-11-30 | 2016-11-30 | Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611077342.9A CN106540051B (en) | 2016-11-30 | 2016-11-30 | Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106540051A CN106540051A (en) | 2017-03-29 |
| CN106540051B true CN106540051B (en) | 2018-07-24 |
Family
ID=58397472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611077342.9A Active CN106540051B (en) | 2016-11-30 | 2016-11-30 | Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106540051B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117100813A (en) * | 2023-08-24 | 2023-11-24 | 陈亮 | Rhinitis ointment and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991649A (en) * | 2009-08-11 | 2011-03-30 | 成新莲 | Medicament for treating allergic rhinitis |
| CN104622924A (en) * | 2014-07-08 | 2015-05-20 | 李秀英 | Medicine for treating rhinitis and production process thereof |
| CN105287772A (en) * | 2015-11-03 | 2016-02-03 | 北京科炎堂生物科技有限公司 | Traditional Chinese medicine antibacterial powder for treating rhinitis and preparation method thereof |
| CN106109582A (en) * | 2016-08-12 | 2016-11-16 | 霍凤珍 | A kind of Chinese medicine for treating rhinitis |
-
2016
- 2016-11-30 CN CN201611077342.9A patent/CN106540051B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991649A (en) * | 2009-08-11 | 2011-03-30 | 成新莲 | Medicament for treating allergic rhinitis |
| CN104622924A (en) * | 2014-07-08 | 2015-05-20 | 李秀英 | Medicine for treating rhinitis and production process thereof |
| CN105287772A (en) * | 2015-11-03 | 2016-02-03 | 北京科炎堂生物科技有限公司 | Traditional Chinese medicine antibacterial powder for treating rhinitis and preparation method thereof |
| CN106109582A (en) * | 2016-08-12 | 2016-11-16 | 霍凤珍 | A kind of Chinese medicine for treating rhinitis |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106540051A (en) | 2017-03-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102772591B (en) | Hollow, ventilation and double-layer traditional Chinese medicine suppository for treating rhinitis and production method of traditional Chinese medicine suppository | |
| CN104857290A (en) | Traditional Chinese medicine disinfection ointment for treating scalds and burns and preparation method thereof | |
| CN104258455B (en) | A kind of medical biological antibacterial dressing and preparation method thereof | |
| CN104825912A (en) | Anti-acne traditional Chinese medicine composition for O2O offline conditioning, and preparation method thereof | |
| CN104173517A (en) | Traditional Chinese medicine preparation and preparation method for treating primary trigeminal neuralgia | |
| CN104435356B (en) | The herbal composite of anti-chicken heat shock | |
| CN106540051B (en) | Treat Chinese medicine composition, pulvis and the paste and preparation method thereof of rhinitis | |
| CN110652544A (en) | Pharmaceutical composition for treating rhinitis and preparation method thereof | |
| CN101810781A (en) | Oral spray agent for treating oral ulcers and preparation method thereof | |
| CN108096344A (en) | A kind of Chinese medicine for treating rhinitis composition | |
| CN105943934A (en) | Scaphium scaphigerum tea capable of clearing and nourishing throat | |
| CN105031170A (en) | Healthcare foot bath powder and preparing method thereof | |
| CN104815155A (en) | Traditional Chinese medicine drops capable of expelling wind, relieving itching and improving eyesight | |
| CN105395587A (en) | Traditional Chinese medicine reagent used for treating nose problems and preparation method thereof | |
| CN104288379B (en) | Traditional Chinese medicine composition for treating dental ulcer | |
| CN104306734B (en) | Treat diabetic gangrene externally applied ointment preparation and preparation method thereof | |
| CN108653431A (en) | Prevent pharmaceutical composition, preparation method and applications and the preparation of rhinitis | |
| CN107823426A (en) | It is a kind of to treat ox into Chinese medicine composition of carbuncle phase pulmonary abscess and preparation method thereof | |
| CN108186960B (en) | A kind of traditional Chinese medicine for treating pharyngitis and preparation method thereof | |
| CN104887808A (en) | Periodontitis treatment traditional Chinese medicine preparation | |
| CN105343609A (en) | Pharmaceutic preparation for treating halitosis to refresh breath and its preparation method | |
| CN103655874B (en) | A kind of topical agent for the treatment of tinea manus and pedis, tinea unguium | |
| CN104906217A (en) | Traditional Chinese medicine ointment for treating acute catarrhal conjunctivitis and preparation method thereof | |
| CN103908598B (en) | A kind of spray for the treatment of beriberi and preparation method thereof | |
| CN102743588B (en) | Preparation method of Chinese medicine irrigation solution for treating abdominal pain type chronic cervicitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |