CN105106590A - Medicine for treating allergic rhinitis - Google Patents

Medicine for treating allergic rhinitis Download PDF

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CN105106590A
CN105106590A CN201510586232.4A CN201510586232A CN105106590A CN 105106590 A CN105106590 A CN 105106590A CN 201510586232 A CN201510586232 A CN 201510586232A CN 105106590 A CN105106590 A CN 105106590A
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parts
fructus
medicine
radix
allergic rhinitis
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于晓菲
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于晓菲
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Abstract

The invention discloses medicine for treating allergic rhinitis, and belongs to the field of traditional Chinese medicine. The medicine is prepared from, by weight, 70-90 parts of saposhnicovia divaricata, 60-80 parts of terminalia chebula retz fruits, 55-75 parts of the roots of straight ladybell, 50-70 parts of fructus arctii, 45-60 parts of milkvetch roots, 40-55 parts of fructus lycii, 35-50 parts of lily, 30-45 parts of flos magnolia flowers, 25-43 parts of long peppers, 22-40 parts of trichosanthes peel roots, 18-35 parts of cynomorium, 15-30 parts of herba siegesbeckiae, 12-25 parts of mint, 8-20 parts of dried earthworms, 5-16 parts of fructus mume and 3-12 parts of fructus xanthii. The selected medicine meets the prescription compatibility theory, the medicine is applied according to disease causes, the functions of expelling wind and removing cold, warming the lung and tonifying the kidney, stopping rhinorrhea and degrading apertures and tonifying the spleen and promoting dieresis are achieved, the absorption effect is good, the curative effect is remarkable, no toxic or side effect or clinical untoward effect exists, and the cure rate of the medicine for allergic rhinitis is high through clinical verifications.

Description

A kind of medicine being used for the treatment of allergic rhinitis
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine being used for the treatment of allergic rhinitis.
Background technology
Allergic rhinitis and allergic dermatitis, the medium primarily of IgE after referring to atopic individuals contact allergen discharges, and has the nasal mucosa non-infectious inflammatory disease that panimmunity competent cell and cytokine etc. participate in.Allergic rhinitis pathological change is telangiectasis, permeability increases and glandular secretion increase and eosinophilic granulocyte infiltration etc., the pathological change catabasis can recover normal, recurrent exerbation, mucosal epithelium layer proliferative can be caused to change, cause mucosa plumpness and Polypoid changes, as concurrent infection, glutinous pus tears or pus tears can be shown as.
In clinical symptoms, allergic rhinitis shows as paroxysmal sneeze, clear water sample nasal mucus, interval or persistence nasal obstruction, the strong gargalesthesia of intranasal, need determine when making a definite diagnosis to belong to intermittent allergic rhinitis or persistence allergic rhinitis, Therapeutic Method conventional at present can select pharmacotherapy, immunotherapy and surgical intervention according to individual specificity.Drug therapy can intranasal administration also can Formulations for systemic administration, conventional oral or nose antihistaminic, glucocorticoid, anti-leukotriene medicine, color paulownia class medicine, intranasal Decongestant, Intranasal anticholinergic agents, and Chinese prescription; Immunization therapy is applicable to the invalid situation of routine medication, adopts subcutaneous injection and sublingual administration, induces clinical and immunologic tolerance, may occur local and systemic adverse reactions; There is obvious anatomic variation with dysfunction to through medicine or immunization therapy without improvement, nasal cavity, merge the special circumstances such as chronic rhinosinusitis coexisting-nasal polyp, be suitable for surgical operation therapy.
Traditional Chinese medical theory is thought, allergic rhinitis be defend that sun is solid by body, invasions of inhibited pulmonary QI, deficiency and cold of both the lung and kidney, kidney-yang deficiency, wind and cold, deficiency of vital energy blood stagnation etc. cause a disease because of initiation, dialectically to treat, when, invigorating spleen to remove dampness sensible with expelling wind and cold, warming the lung the kidney invigorating, only tears is for purport, reasonable compatibility Chinese prescription, thus improve immunity of organisms, lung qi dispersing dampness removing, strengthen Respiratory ft tive resistance, reach the object for the treatment of of allergic rhinitis.
Summary of the invention
The invention provides a kind of medicine being used for the treatment of allergic rhinitis, have that expelling wind and cold, warming the lung the kidney invigorating, only tears are sensible, effect of invigorating spleen to remove dampness, cure the disease and ask source treating both the principal and secondary aspects of a disease, to the allergic rhinitis that a variety of causes causes, all there is good curative effect.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a medicine for allergic rhinitis, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Be used for the treatment of a preparation method for the medicine of allergic rhinitis, comprise following processing step:
(1) being fried with high heat by terminalia flesh to surface is buff, takes out after cooling, pulverizes in the lump grind into powder with dry Pheretima, crosses 120 order fine powders, for subsequent use.
(2) Radix Astragali, Bulbus Lilii Mel are mixed thoroughly, slow fire is fried to surperficial glassy yellow and tack-free, takes out after cooling, grinds into powder, crosses 120 order fine powders, for subsequent use.
(3) Radix Saposhnikoviae, Radix Adenophorae (Radix Glehniae), Fructus Arctii, Flos Magnoliae flower, Fructus Piperis Longi, Pericarpium Trichosanthis Gen, Herba Siegesbeckiae, Herba Menthae, Fructus Mume, Fructus Xanthii are put into container, add the water of octuple amount, boil rear immersion 8 ~ 10 hours, get and boil liquid; In remaining medicinal residues, add the water of six times amount again, boil rear immersion 6 ~ 8 hours, get and boil liquid; Merge twice gained and boil liquid, under heating evaporation simmer down to 60 DEG C of environment, the thick paste of relative density 1.10 ~ 1.15, for subsequent use.
(4) Fructus Lycii, Herba Cynomorii are put into container, add the shao-hsing rice wine of four times amount, boil rear immersion 3 ~ 4 hours, get and boil liquid; In remaining medicinal residues, add the shao-hsing rice wine of triplication again, boil rear immersion 2 ~ 3 hours, get and boil liquid; Merge twice gained and boil liquid, under heating evaporation simmer down to 60 DEG C of environment, the thick paste of relative density 1.10 ~ 1.15, for subsequent use.
(5) by the fine powder of step (1), step (2) gained, the thick paste mixing and stirring obtained with step (3), step (4), quick-freezing Cheng Fenhou is prepared as tablet.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Saposhnikoviae: acrid in the mouth; Micro-sweet; Slightly warm in nature.Return lung; Bladder; Liver; Spleen channel.Deliver; Dispel the wind; Victory is wet; Pain relieving.Cure mainly anemofrigid cold; Flu folder is wet; Headache; Giddy; Cold-damp is suffered from abdominal pain; Have loose bowels; Rheumatic arthralgia; Spasm of the limbs; Tetanus; Conjunctival congestion; Skin infection; Hernia abdominal mass; Scabies; Rubella." Japan hanako materia medica " year: " arresting lacrimation and paralysis delay, tonneau the five internal organs GUAN-pulse, five kinds of strain and seven kinds of impairment, thin damage night sweat, vexed body weight, energy tranquilizing the mind, even gaseous pulse for invigorating middle warmer benefit god, blepharitis marginalis." modern medicine study confirmation, anti-wind energy significantly improves the hypoxia-bearing capability of acute cerebral hypoxia, significantly suppresses the formation of external lipid peroxide of bringing out, has antioxidant activity, shield to neurocyte.
Terminalia flesh: bitter in the mouth; Acid; Puckery; Property is put down.Enter lung; Large intestine channel.Astringing intestine to stop diarrhea is astringed the lung; Pathogenic fire reducing sore-throat relieving.Cure mainly chronic diarrhea chronic dysentery; To have blood in stool proctoptosis; The deficiency of the lung is breathed with cough; Chronic cough is more than; Pharyngalgia hoarseness." property of medicine opinion " carries: " tonneau body fluid, main broken chest stagnation of QI, sealing road, astringes the lung, and five types of dysphagia is tied." modern medicine study shows, terminalia flesh is rich in tannin, has the effect of convergence, antidiarrheal, and water decoction is effective to multiple dysentery bacterium, and remarkable to bacillus pyocyaneus, diphtheria corynebacterium effect, ethanol extract has antibacterial and antifungic action, has spasmolysis to smooth muscle.
Radix Adenophorae (Radix Glehniae): sweet in the mouth; Micro-hardship; Cold nature.Return lung; Stomach warp.Replenishing YIN and removing heat; Moistening the lung and resolving phlegm; Reinforcing stomach reg fluid.Cure mainly deficiency of YIN chronic cough; Consumptive disease is coughed expectorant blood; Cough caused by dryness expectorant is few; Deficiency-heat sore throat; Tianjin wound is thirsty.Compendium of Material Medica is carried: " Radix Adenophorae (Radix Glehniae) is sweet light and cold, and its body is gently empty, special tonifying the lung gas, thus strengthening the spleen and kidney, therefore gold can should it by fire gram person.YANG invigorating and raw cloudy, nourishing YIN and sun processed." modern medicine study confirms; Radix Adenophorae (Radix Glehniae) contains volatile oil, coumarin, starch, alkaloid, triterpenic acid, stigmasterol, β-each sterol; improve T cell ratio; improve lymhocyte transformation rate, leukocyte increasing, strengthens macrophage function; extend antibody life period; have antipyretic, ease pain, eliminate the phlegm, function of relievining asthma, strengthen the immunologic function of body fluid and cell, have protection and inhibitory action to irritability and Drug gastric ulcer.
Fructus Arctii: acrid in the mouth; Bitter; Cold in nature.Return lung; Stomach warp.Dispelling wind and heat pathogens; Lung qi dispersing rash; Sore-throat relieving eliminating stagnation; Removing toxic substances and promoting subsidence of swelling.Cure mainly cough due to pathogenic wind-heat; Laryngopharynx swelling and pain; Macule is not saturating; Rubella pruritus; Sore swollen toxin." medicineization justice " carries: " can rise and can fall, power relieving heat toxin, hardship can be relieved inflammation or internal heat, pungent energy dispelling wind, Your Majesty portion wind-phlegm, the edema of the face, discomfort in the throat, all scorchingly hot heap soil or fertilizer over and around the rootss." modern medicine study shows, Fructus Arctii can suppress urinary protein excretion to increase, and improves Biochemical Indices In Serum, significantly and enduringly can reduce blood glucose, has inhibitory action to uterus and intestinal tube, and contained arctigenin has active anticancer.
The Radix Astragali: sweet in the mouth; Warm in nature.Enter the heart; Lung; Spleen; Kidney channel.Invigorating QI to consolidate the body surface resistance; Diuresis; Expelling pus and toxin by strengthening QI; Promoting tissue regeneration and ulcer healing.Cure mainly cardiopalmus of breathing hard; Asthenia; Weak; Spontaneous perspiration; Night sweat; Chronic diarrhea; Proctoptosis; Body is impractical swollen; Uterine prolapse; Chronic nephritis; Carbuncle difficulty is burst; Or burst do not hold back for a long time." herbal outline " carries: " have the function of invigorating QI to consolidate the body surface resistance, expelling pus and toxin by strengthening QI, granulation promoting." modern medicine study confirms; Radix Astragali main component is Radix Astragali total flavones, Radix Astragali Mongolici total polysaccharide, Radix Astragali total saponins and aminoacid etc.; have diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxidant radical generate and improve the multiple pharmacological effect such as body's immunity; can act on body from many aspects, improves the relevant blood vessel sexually transmitted disease (STD)s such as cardiovascular, cerebrovascular, diabetes, nephropathy and becomes the functions such as the hemodynamics of patient and vascular endothelial cell.
Fructus Lycii: sweet in the mouth; Property is put down.Return liver; Kidney; Lung meridian.Nourishing the liver; Nourishing kidney; Lung moistening.Cure mainly caused by liver and kidney deficiency; Have a dizzy spell; Visual one clear; Soreness of the waist and knees; The expensive essence of sexual impotence; Cough due to consumptive disease; To quench one's thirst taking fluids profusely." book on Chinese herbal medicine just " carries: " improve visual and auditory acuity, adds the solid marrow of essence, strengthen the muscle and bone, and kind benefit impairment caused by overstrain, especially only quenches one's thirst." modern medicine study confirms, Fructus Lycii scalable body's immunity, can effectively grow and cell mutation, there is the effect of the aspect such as slow down aging, anti-fatty liver, adjusting blood lipid and blood glucose, promotion hemopoietic function by Tumor suppression.
Bulbus Lilii: sweet in the mouth; Micro-hardship.Cold nature.Enter the heart; Lung meridian.Nourishing YIN and moistening the lung; Clearing away heart-fire for tranquillization.Cure mainly deficiency of YIN chronic cough; Sputum mixed with blood; The calentura later stage; Waste heat is unclear; Or the unsuccessful caused fidgets due to deficiency palpitation with fear of feelings will; Insomnia and dreamful sleep; Absentminded; Carbuncle; Eczema." Japan hanako materia medica " carries: " feel at ease, determine gallbladder, beneficial will, support the five internal organs.Control insane heresy crow position, madly to cry, palpitation with fear, it is swollen to kill diseases due to noxious agents produced by various parasites Qi , Xie acute mastitis, carbuncle on the back and all skin ulcers, and the mad fortune of blood after managing property." modern medicine study shows, Bulbus Lilii have significantly eliminate the phlegm, antitussive effect, have significant protective effect to adrenal cortex function exhaustion, extend hypoxia endurance time, also have effect that calmness, nourishing YIN and moistening the lung, anticancer are bred in addition.
Flos Magnoliae flower: acrid in the mouth; Warm in nature.Enter lung; Stomach warp.Dispersing wind and cold; Clearing the nasal passage.Main nasal sinusitis; The headache of anemofrigid cold; Nasal obstruction; Watery nasal discharge.Compendium of Material Medica is carried: " control nasal abscess after nasal sinusitis, stuffy nose, nasal abscess and pox, dispel the wind, let out lung non-return, promoting the circulation of QI is broken to be stopped up." modern medicine study shows, Flos Magnoliae has local convergence, stimulation and anesthetic action, has antibacterial, antiinflammatory significantly and analgesia function, can excited uterus and intestinal smooth, also has the effect of antiallergic, antihistamine, antianaphylaxis asthma in addition.
Fructus Piperis Longi: acrid in the mouth; Hot in nature.Return spleen; Stomach; Large intestine; Lung; Bladder; Liver; Kidney channel.Warming spleen and stomach for dispelling cold; Therapeutic method to keep the adverse QI flowing downwards pain relieving.Cure mainly coldness and pain in the epigastrium; Vomiting; Have loose bowels; Headache; Nasal sinusitis." detailed outline " carries: " be headache, nasal sinusitis, toothache key medicine, get it and hotly can enter Yangming Channel and fall apart superficial heat also." modern medicine study shows; the volatile oil contained by Fructus Piperis Longi all has inhibitory action to staphylococcus aureus, bacillus subtilis, Bacillus cereus, tubercule bacillus, dysentery bacterium, influenza virus; diastole coronary artery; reduce blood fat; suppress the formation and development of As; promote cholesterol esterification, also has convulsion, sedation in addition.
Pericarpium Trichosanthis root: sweet-bitter flavor; Cold in nature.Enter lung; Stomach warp.Lung moistening; Reduce phlegm; Eliminating stagnation; Intestine moistening.Cure mainly phlegm-heat cough; The thoracic obstruction; Blocked-up chest; Consumptive lung disease hemoptysis; Quench one's thirst; Jaundice; Constipation; Carbuncle from the beginning of." detailed outline " carries: " lung moistening is dry, pathogenic fire reducing, and the main thoracic obstruction, controls cough, and clearing away phlegm is tied, logical hot and suffocating in the heart." modern medicine study confirms, Pericarpium Trichosanthis root master containing triterpene saponin, fatty oil, several amino acids and alkaloid, have eliminate the phlegm, coronary artery dilator, increase coronary flow, anti-hypoxia, blood fat reducing effect, the treatment clinically for coronary heart disease has good curative effect.
Herba Cynomorii: sweet in the mouth; Warm in nature.Return kidney; Liver; Large intestine channel.Kidney invigorating and YANG supporting; The relieving constipation of benefit intestinal.Cure mainly impotence due to deficiency of the kidney; Seminal emission premature ejaculation; Leftover bits and pieces flaccidity is soft; Empty people's constipation." book on Chinese herbal medicine is looked for the truth " carries: " all cloudy deficiency of vital energys are damaged, and essence and blood is decayed, and constipation due to dry stool can be used, and nourishing YIN gas, controls void." modern medicine study shows; Herba Cynomorii all has regulating action for body non-specific immunity and cellular immune function; have potentiation to humoral immune function; excited intestinal tube; increase enterokinesia; improve cortisol levels, to hormone antagonist to adrenocortical exogenous suppression, also has anti-rotation record and anticancer effect in addition.
Herba Siegesbeckiae: bitter in the mouth; Pungent; Cold in nature; Slightly poisonous.Return liver; Kidney channel.Wind-damp dispelling; The meridian dredging; Heat clearing away is only malicious.Cure mainly rheumatic arthralgia; Stiffness of the muscle and joint; Weakness of the waist and knees; Hemiplegia; Hypertension; Malaria; Jaundice; Carbuncle; Sore; Rubella eczema; Insect and animal biting.Tang Materia Medica carries: " disconnected blood, raw meat, except all malignant boil, disappear edema, row large intestine gas, tonify deficiency, settling five organs, wind-damp dispelling disease for main incised wound, pain relieving." modern medicine study confirms, Herba Siegesbeckiae has blood pressure lowering, blood vessel dilating, antiinflammatory action, can improve body's immunity, inhibition thrombosis, promotes restoration of blood flow after microcirculation disturbance, in addition antibacterial, malaria and antioxidation in addition.
Herba Menthae: acrid in the mouth; Micro-hardship; Property is put down.Enter lung meridian.Dispelling wind to relieve the exterior syndrome; Lung qi dispersing cough-relieving.Cure mainly flu; Cough; Pertussis; External oculopathy corneal nebula; Burn due to hot liquid or fire." Tian Bao book on Chinese herbal medicine " carries: " cold expelling relieves inflammation or internal heat, and delivers cold expelling, and lung qi dispersing cough-relieving, controls cough due to wind and cold, all pains." modern medicine study shows, the Mentholum contained by Herba Menthae and Oleum menthae have that special awns is fragrant, pungent sense and cool feeling, are widely used in the medicines such as wind dispelling, anticorrosion, antiinflammatory, analgesia, antipruritic, stomach invigorating; have and disperse wind heat; clearing throat, rash is detoxified, dispersing the stagnated live-QI to relieve the stagnation of QI and the effect such as antipruritic.
Dry Pheretima: salty in the mouth; Cold in nature.Return liver; Spleen; Urinary bladder channel.Clear gesture relieving convulsion; Suppressing the hyperactive liver to relieve the wind syndrome; Dredge the meridian passage; To relieving asthma diuresis.Cure mainly calentura heating mad dry; Infantile convulsion is twitched; Headache due to hyperactivity of liver-YANG; Apoplectic hemiplegia; Rheumatic arthralgia; Dyspnea and cough due to lung-heat; Urinary obstruction.Compendium of Material Medica is carried: " cold in nature and descending, cold in nature therefore can separate all hot diseases, descending former energy diuresis, controls sufficient disease and the meridian dredging also." " main typhoid fever malaria, large fanatical tired, and children's's adult urinary obstruction, anxious chronic infantile convulsion, severe and migratory arthralgia pain." modern medicine study proves, Pheretima contains the compositions such as ground LONGSU, lumbrofebrin, vitamin B complex complex, there is diuresis, ease pain, relieving asthma, blood pressure lowering, the effect such as antipyretic, convulsion.
Fructus Mume: sour in the mouth; Property is put down.Enter liver; Spleen; Lung; Kidney; Stomach; Large intestine channel.Astringing lung-QI and relieving cough; Relieving diarrhea with astringents; Hemostasis; Promote the production of body fluid.Cure mainly chronic cough; Deficiency-heat excessive thirst; Chronic malaria; Chronic diarrhea; Dysentery; Vomiting." detailed outline " carries: " astringing intestine to stop diarrhea of astringing the lung, controls chronic cough, dysentery, and regurgitation is dysphagic, ascariasis of biliary tract vomiting and diarrhea, and detumescence, gushes expectorant, parasite killing, separates ichthyotoxin, horse mump, sulfur poison." modern medicine study confirmation; Fructus Mume has obvious antibacterial action; all have inhibitory action to dysentery bacterium, bacillus pyocyaneus, Bacillus typhi, escherichia coli, tubercule bacillus, Bacillus proteus, staphylococcus aureus, messy vibrio and various dermatophytes; and the hormonal secretion of the parotid gland can be stimulated; and clearization blood, strengthens metabolic function.
Fructus Xanthii: bitter in the mouth; Sweet; Pungent.Warm in nature; Slightly poisonous.Return lung; Liver Channel.Dispersing wind and cold; Clearing the nasal passage; Wind-damp dispelling; Antipruritic.Cure mainly nasal sinusitis; Headche due to wind-cold; Rheumatic arthralgia; Rubella; Eczema; Scabies.Essentials of Matea Medica carries: " kind diaphoresis, loose rheumatism, upper logical brain top, descending sufficient knee joint, reaches skin outward.Control headache, order is dark, toothache, nasal sinusitis, deburring." modern medicine study shows, Fructus Xanthii has obvious antiinflammatory, antibacterial, blood sugar lowering and of short duration hypotensive effect, also has the effectiveness alleviated convulsions symptom, strengthen respiratory function in addition.
The present invention compared with prior art, has following beneficial effect:
The present invention selects medical material to meet a monarch and his subjects left side and makes it reason, suits the remedy to the case for the cause of disease, has that expelling wind and cold, warming the lung the kidney invigorating, only tears are sensible, effect of invigorating spleen to remove dampness, good absorbing effect, evident in efficacy, have no side effect and clinical adverse, higher to allergic rhinitis cure rate through clinical verification.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The processing step of process for preparing medicine of the present invention is:
(1) being fried with high heat by terminalia flesh to surface is buff, takes out after cooling, pulverizes in the lump grind into powder with dry Pheretima, crosses 120 order fine powders, for subsequent use.
(2) Radix Astragali, Bulbus Lilii Mel are mixed thoroughly, slow fire is fried to surperficial glassy yellow and tack-free, takes out after cooling, grinds into powder, crosses 120 order fine powders, for subsequent use.
(3) Radix Saposhnikoviae, Radix Adenophorae (Radix Glehniae), Fructus Arctii, Flos Magnoliae flower, Fructus Piperis Longi, Pericarpium Trichosanthis Gen, Herba Siegesbeckiae, Herba Menthae, Fructus Mume, Fructus Xanthii are put into container, add the water of octuple amount, boil rear immersion 8 ~ 10 hours, get and boil liquid; In remaining medicinal residues, add the water of six times amount again, boil rear immersion 6 ~ 8 hours, get and boil liquid; Merge twice gained and boil liquid, under heating evaporation simmer down to 60 DEG C of environment, the thick paste of relative density 1.10 ~ 1.15, for subsequent use.
(4) Fructus Lycii, Herba Cynomorii are put into container, add the shao-hsing rice wine of four times amount, boil rear immersion 3 ~ 4 hours, get and boil liquid; In remaining medicinal residues, add the shao-hsing rice wine of triplication again, boil rear immersion 2 ~ 3 hours, get and boil liquid; Merge twice gained and boil liquid, under heating evaporation simmer down to 60 DEG C of environment, the thick paste of relative density 1.10 ~ 1.15, for subsequent use.
(5) by the fine powder of step (1), step (2) gained, the thick paste mixing and stirring obtained with step (3), step (4), quick-freezing Cheng Fenhou is prepared as tablet.
Usage and dosage: adult every day 3 times, each 250 ~ 400mg, one hour after meal warm water delivery service, adds when serious symptom person has a stuffy nose and takes once, dosage 150mg, within 12 days, is a course for the treatment of, and general 2 ~ 4 courses for the treatment of take effect.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection
Select the routine clinical observation of Allergic Rhinitis 80 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random.Treatment group 40 example, wherein male 23 example, women 17 example, 22 ~ 55 years old age, 42.6 years old mean age.Matched group 40 example, wherein male 24 example, women 16 example, 19 ~ 57 years old age, 41.4 years old mean age.Two groups of qualifications and record of service are basically identical, without significant difference, have comparability.
2, treatment group patient takes medicine of the present invention, adult every day 3 times, each oral 300mg grain, the more than or tears of nasal obstruction tears stream and do not go out time, adding 1 150mg, 12 days is a course for the treatment of.Matched group gives antiallergic agent mist nasal cavity and sprays, and is aided with the treatment of oral wide spectrum Claritin.
3, efficacy determination:
(1) fully recover: paroxysmal sneeze stops, and watery nasal discharge transference cure, nasal cavity is unobstructed, and gargalesthesia disappears.
(2) take a turn for the better: sneeze, thin nasal discharge, nasal obstruction, rhinocnesmus symptom alleviate or take a turn for the better.
(3) invalid: symptom is with treating front no significant difference.
4, result
Cure 27 examples in treatment group, take a turn for the better 9 examples, invalid 4 examples, cure rate 67%, total effective rate 90%.
Cure 8 examples in matched group, take a turn for the better 11 examples, invalid 21 examples, cure rate 20%, total effective rate 47%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, old ××, man, 16 years old, student.Patient's readme, because attending a day school in school, gets up comparatively early winter, just suffered from allergic rhinitis before 2 years, every day, WA minimumly will make a call to more than 10 sneeze, rhinorrhea, all day is in a daze, easy drowsiness, health is weak, sometimes also can have a headache, how many clinics have not been known for this reason, only see the doctor and buy medicine and just spent 10,000 polylith money, but lose a bit improvement, have the trend of deterioration on the contrary.Because recently there is dizziness, coming institute and going to a doctor, being diagnosed as allergic rhinitis, advising it to take medicine of the present invention.Through following the tracks of inquiry, basic controlling Rhinitis Symptoms after two courses for the treatment of, is now just taking the 3rd course for the treatment of.
2, Shen ××, female, 28 years old, teacher.Patient's readme, before 3 years after family finishing, occur rhinocnesmus, nasal obstruction, stream clear water nasal mucus, sneeze is allergic rhinitis to local hospital inspection, gives nose spray hormone therapy, poor effect.Before 2 years, start, outside rhinocnesmus, nasal obstruction, snivel, sneeze symptom, to occur pus nasal mucus, and flow backwards to oral cavity after nose, breathe heavily night and suppress, develop into allergic asthma after diagnosing.After taking 3 courses for the treatment of of medicine of the present invention, rhinocnesmus, nasal obstruction, thin nasal discharge, sneeze symptom are clearly better, and after continuing to take 2 courses for the treatment of of medicine of the present invention, Rhinitis Symptoms is almost recovered, and accidental intermittence cough, on daily life without impact.
3, garden ××, man, 43 years old, office worker.Patient's readme suffered from allergic rhinitis more than 4 years, nasal obstruction, rhinorrhea repeatedly, madly must sneeze battle array every morning to do, medication is failed to respond to any medical treatment really voluntarily, and recurrent exerbation, after 2 years, is still nasal mucus as clear water, severe nasal blockage, with headache syndromes, and start have slight asthma to occur, be often in flu state.Within nearly three days, symptom obviously increases the weight of, and after medical to institute, follow the doctor's advice and take medicine of the present invention, normal dose basis adds and takes once, after 3 courses for the treatment of, thin nasal discharge, nasal obstruction, headache syndromes are obviously alleviated, in the middle of existing positive continued treatment.

Claims (3)

1. be used for the treatment of a medicine for allergic rhinitis, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Saposhnikoviae 70 ~ 90 parts of terminalia flesh 60 ~ 80 parts of Radix Adenophorae (Radix Glehniae) 55 ~ 75 parts of Fructus Arctiis 50 ~ 70 parts
The Radix Astragali 45 ~ 60 parts of Fructus Lycii 40 ~ 55 portions of Bulbus Liliies 35 ~ 50 parts of Flos Magnoliae spend 30 ~ 45 parts
Fructus Piperis Longi 25 ~ 43 parts of Pericarpium Trichosanthis roots 22 ~ 40 parts of Herba Cynomorii 18 ~ 35 Fen Herba Siegesbeckiaes 15 ~ 30 parts
The dry Pheretima of Herba Menthae 12 ~ 25 parts 8 ~ 20 portions of Fructus Mumes 5 ~ 16 portions of Fructus Xanthii 3 ~ 12 parts.
2. a kind of medicine being used for the treatment of allergic rhinitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Saposhnikoviae 80 parts of terminalia flesh 70 parts of Radix Adenophorae (Radix Glehniae) 65 parts of Fructus Arctiis 60 parts
The Radix Astragali 52 parts of Fructus Lycii 48 portions of Bulbus Liliies 43 parts of Flos Magnoliae spend 38 parts
Fructus Piperis Longi 34 parts of Pericarpium Trichosanthis roots 30 parts of Herba Cynomorii 26 Fen Herba Siegesbeckiaes 23 parts
The dry Pheretima of Herba Menthae 18 parts 14 portions of Fructus Mumes 10 portions of Fructus Xanthii 8 parts.
3. be used for the treatment of a preparation method for the medicine of allergic rhinitis, it is characterized in that: comprise following processing step:
(1) being fried with high heat by terminalia flesh to surface is buff, takes out after cooling, pulverizes in the lump grind into powder with dry Pheretima, crosses 120 order fine powders, for subsequent use;
(2) Radix Astragali, Bulbus Lilii Mel are mixed thoroughly, slow fire is fried to surperficial glassy yellow and tack-free, takes out after cooling, grinds into powder, crosses 120 order fine powders, for subsequent use;
(3) Radix Saposhnikoviae, Radix Adenophorae (Radix Glehniae), Fructus Arctii, Flos Magnoliae flower, Fructus Piperis Longi, Pericarpium Trichosanthis Gen, Herba Siegesbeckiae, Herba Menthae, Fructus Mume, Fructus Xanthii are put into container, add the water of octuple amount, boil rear immersion 8 ~ 10 hours, get and boil liquid; In remaining medicinal residues, add the water of six times amount again, boil rear immersion 6 ~ 8 hours, get and boil liquid; Merge twice gained and boil liquid, under heating evaporation simmer down to 60 DEG C of environment, the thick paste of relative density 1.10 ~ 1.15, for subsequent use;
(4) Fructus Lycii, Herba Cynomorii are put into container, add the shao-hsing rice wine of four times amount, boil rear immersion 3 ~ 4 hours, get and boil liquid; In remaining medicinal residues, add the shao-hsing rice wine of triplication again, boil rear immersion 2 ~ 3 hours, get and boil liquid; Merge twice gained and boil liquid, under heating evaporation simmer down to 60 DEG C of environment, the thick paste of relative density 1.10 ~ 1.15, for subsequent use;
(5) by the fine powder of step (1), step (2) gained, the thick paste mixing and stirring obtained with step (3), step (4), quick-freezing Cheng Fenhou is prepared as tablet.
CN201510586232.4A 2015-09-16 2015-09-16 Medicine for treating allergic rhinitis Pending CN105106590A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105213761A (en) * 2015-11-20 2016-01-06 王秀娟 A kind of tablet and preparation method being used for the treatment of allergic rhinitis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520461A (en) * 2013-11-03 2014-01-22 李勇 Medicine for treating allergic rhinitis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103520461A (en) * 2013-11-03 2014-01-22 李勇 Medicine for treating allergic rhinitis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105213761A (en) * 2015-11-20 2016-01-06 王秀娟 A kind of tablet and preparation method being used for the treatment of allergic rhinitis

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