CN110237174A - A kind of eliminating dampness Chinese medicine composition and preparation method thereof for treating cold cough - Google Patents
A kind of eliminating dampness Chinese medicine composition and preparation method thereof for treating cold cough Download PDFInfo
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Abstract
The invention discloses a kind of eliminating dampness Chinese medicine compositions and preparation method thereof for treating cold cough, it is related to technical field of traditional Chinese medicines, raw material includes: 5-12 parts of elscholtiza, 7-15 parts of schizonepeta, 15-25 parts of waxgourd peel, 7-15 parts of dried orange peel, 5-12 parts of blackberry lily, 10-18 parts of bulbus fritillariae cirrhosae, 5-12 parts of campanulaceae, 10-18 parts of loguat leaf, 10-18 parts of mulberry leaf, 10-18 parts of kiss-me, 5-12 parts of Cortex Magnoliae Officinalis, 5-12 parts of Radix Glycyrrhizae by weight.The preferred multi-flavor natural traditional Chinese medicine raw material of invention, all medicines share, altogether long memorial dissipating wind-heat, expel pathogenic wind from the body surface, be eliminating dampness and eliminating phlegm, clearing lung and relieving cough, eliminating phlegm and relieving asthma, clearing heat, relieving sore-throat function, can be used for treating influenza fever, headache cough, malasia, the diseases such as pharyngodynia with dryness are suitable for flu incubation period or sick hair phase, being capable of effective symptoms such as cough, abscess of throat caused by the preventing cold later period, curative for effect, safety is without side-effects.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines more particularly to a kind of eliminating dampness Chinese medicine composition for treating cold cough and its systems
Preparation Method.
Background technique
Flu is the most common acute infections of respiratory tract disease, is in self limiting more, and incidence is higher.Adult annual generation
2~4 times, children's incidence is higher, and annual 6~8 times.Whole year can all fall ill, and winter-spring season is more.Mostly caused by rhinovirus, secondly
Cause for coronavirus, parainfluenza virus, Respiratory Syncytial Virus(RSV), echovirus, Coxsackie virus etc..Onset is more anxious, hides
Phase is differed for 1~3 day, and different with virus, enterovirus is shorter, and adenovirus, Respiratory Syncytial Virus(RSV) etc. are longer.Period of disease, 2~3 days
Nasal mucus retrogradation afterwards, often with pharyngalgia, shed tears, hypogeusia, unsmooth breath, trachyphonia etc..It, the self-healing phase, 5~7 days can such as without complication
Recovery from illness.That is it without other complication, fully recovers automatically in one week.With the progress of society, industrial high development, air ring
Border also gradually meets a severe test, and haze weather also gradually occurs in various regions.People flu after by air environment influenced
Also increasing, flu often causes other symptoms, and the unclean air of the sucking in respiratory tract is especially caused to lead to secretion
Or foreign matter makes cough caused by respiratory tract infection inflammation, if flu early period is not treated in time, no matter later transformation has at cough
Phlegm or non-productive cough are often continuous more days and are difficult to fully recover, and with chest pain, expiratory dyspnea etc., serious person can be transformed into branch gas
The series of disease such as pipe inflammation, influence health.
Chinese medicine thinks perverse trend caused by nature has had six kinds of weathers too backward, is exactly wind, cold, heat, wet, dry, fiery.?
This is six kinds of nature weathers under normal circumstances, but when human body does not tolerate, resistance is reduced, cause human body disease when
It waits, they become perverse trend.This six kinds of perverse trends can individually invade human body, cause disease, can also be two or more
Human body is invaded altogether, causes human body diseases.This six kinds of extraneous perverse trend is to enter human body from fur or mouth and nose.Chinese medicine is recognized
Return kidney to lead again by fur or mouth and nose, so causing this cold-evil come from appearance, just causes the not normal of lungs function, draw
Play cough.
The treatment method of cold cough mainly uses doctor trained in Western medicine smelting to treat at present, but many smeltings treat flu drug belong to it is anti-
Crude drug object, and the ingredient for also causing people drowsiness containing chlorpheniramine, side effect are big.Relative to Western medicine, Chinese medicine Small side effects, more
It is green safe.Some Chinese materia medica preparation curative effects for treating cold cough at present on the market are slower, therefore, invent a kind of curative effect
Obviously, it is urgently to be resolved that the Chinese medicine for treating cold cough that is quick, being not easy repeatedly, have no toxic side effect becomes those skilled in the art
The problem of.
Summary of the invention
Technical problems based on background technology, the invention proposes a kind of eliminating dampness Chinese traditional medicine compositions for treating cold cough
Object and preparation method thereof can be used for treating influenza fever, and headache is coughed, malasia, the diseases such as pharyngodynia with dryness, and curative effect is true
It cuts.
A kind of eliminating dampness Chinese medicine composition for treating cold cough proposed by the present invention, raw material includes: elscholtiza by weight
5-12 parts, 7-15 parts of schizonepeta, 15-25 parts of waxgourd peel, 7-15 parts of dried orange peel, 5-12 parts of blackberry lily, 10-18 parts of bulbus fritillariae cirrhosae, campanulaceae 5-12
Part, 10-18 parts of loguat leaf, 10-18 parts of mulberry leaf, 10-18 parts of kiss-me, 5-12 parts of Cortex Magnoliae Officinalis, 5-12 parts of Radix Glycyrrhizae.
Preferably, the loguat leaf is honeydew loguat leaf.
Preferably, the Radix Glycyrrhizae is radix glycyrrhizae preparata.
Preferably, the Chinese medicine composition is tablet, granule, capsule, pill or oral solution.
The invention also provides the preparation methods of the eliminating dampness Chinese medicine composition of above-mentioned treatment cold cough, including following step
It is rapid:
S1, schizonepeta, waxgourd peel, dried orange peel, campanulaceae, loguat leaf, mulberry leaf, Radix Glycyrrhizae are crushed, mixing is soaked in water, decoction mentions
It takes, filters, concentrate filtrate to clear cream, it is 45-55% that ethyl alcohol, which is added, and adjusts alcohol content, is stood, filtering obtains refining liquid；
S2, elscholtiza, blackberry lily, bulbus fritillariae cirrhosae, kiss-me, Cortex Magnoliae Officinalis are crushed, 70% ethanol solution dipping is added, then in mixing
Diacolation is carried out using 65-70% ethanol solution, collects percolate；
S3, refining liquid and percolate are mixed, recycles ethyl alcohol, be concentrated under reduced pressure, spray drying obtains major ingredient；
S4, pharmaceutically acceptable auxiliary material is added into major ingredient, preparation is made according to a conventional method.
Preferably, in S1,2-4h is soaked in water, decocts extraction 2 times, decocts extract 1-3h for the first time, second of decoction mentions
0.5-1.5h is taken, decocts 6-10 times for extracting water consumption as medicinal material initial mass every time.
Preferably, in S1, the clear cream that relative density is 1.00-1.03 (50 DEG C of survey) is concentrated filtrate to.
Preferably, in S1,20-26h is stood.
Preferably, in S2,70% ethanol solution is added and impregnates 1-2h.
Preferably, in S2, diacolation is 4-6 times of medicinal material initial weight with the dosage of 65-70% ethanol solution, and the diacolation time is
7-10h。
Each Chinese medicine material effect is as follows in the present invention:
Elscholtiza: slightly warm in nature, acrid flavour, distributed in lung channel, stomach meridian have the effect of inducing sweat and dispelling exogenous evils, medium wet；Pharmacological research table
Bright, elscholtiza has antipyretic effect, has inhibiting effect in vitro intestines, can enhance immunity of organism, has stronger broad-spectrum antiseptic
Effect has certain antivirus action；Still there are diuresis, antibechic and phlegm-dispelling functions.
Schizonepeta: slightly warm in nature, acrid flavour, distributed in lung channel, Liver Channel have the effect of delivering relieve heat, promoting eruption；Pharmacological research shows chaste tree
Mustard has antipyretic and cooling effect, and calm, analgesia can promote sweat gland secretion, have obvious anti-inflammatory effect, have apparent eliminating the phlegm
And antiasthmatic effect, there is stronger antioxidation and anti-microbial effect.
Waxgourd peel: it is sweet in flavor, cool in nature, return small intestinl channel, stomach meridian, there is the effect of reducing fever and causing diuresis, detumescence；Waxgourd peel has diuresis
Effect, increases urination rate.
Dried orange peel: acrid flavour, bitter, warm-natured, converge to the spleen channel, lung channel have the effect of qi-regulating appetizing, eliminating dampness and eliminating phlegm；Pharmacological research
Showing that dried orange peel can adjust digestive system, eliminating the phlegm of relievining asthma enhances immune function, and it is anti-inflammatory, the digestive juices such as saliva, gastric juice point can be promoted
Secrete and eliminate enteral pneumatosis.
Blackberry lily: cold in nature, bitter, it is distributed in lung channel, there is the effect of clearing heat and detoxicating, dissolving phlegm, relieving sore-throat；Pharmacological research shows blackberry lily
With anti-inflammatory, antipyretic, antiallergy, antimicrobial, eliminating the phlegm, anticoagulation, promote salivary secretion, blood pressure lowering, cholagogue, diuresis, enhancement
The effects of neuronal cell survival and growth.
Bulbus fritillariae cirrhosae: cold nature, bitter, sweet, distributed in lung channel, the heart channel of Hang-Shaoyin has the effect of clearing heat and moistening lung, preventing phlegm from forming and stopping coughing；Animal is real
It tests and shows that Bulbus Fritillariae Cirrhosae extract has relieving cough and reducing sputum, decompression, antiinflammation, In vitro Bactericidal Experiments show alcohol extracting thing to golden yellow
Staphylococcus and Escherichia coli have obvious inhibiting effect.
Campanulaceae: it is mild-natured, it is bitter, pungent, it is distributed in lung channel, there is the effect of clearing lung and eliminating the phlegm, relieving sore throat and evacuating pus；Pharmacological research shows tangerine
Root, stem, leaf, flower and the fruit of stalk have the phlegm-dispelling functions of highly significant, and Radix Platycodonis extract and platycodin are to rat or cavy
Intraperitoneal injection have antitussive effect, have the function of anti-inflammatory, antiulcer, expansion blood vessel, can reducing heart rate, inhibit breathe and subtract
Weak atrial contractility.
Loguat leaf: bitter, cold nature, distributed in lung channel, stomach meridian have the effect of clearing lung and relieving cough, stopping nausea and vomiting by lowering the adverse flow of QI；Pharmacological testing table
Bright, loguat leaf has calmness to respiratory center, relievings asthma, antitussive effect.
Mulberry leaf: cold in nature, sweet in flavor, bitter, distributed in lung channel, Liver Channel has the effect of dispelling wind and heat from the body, clearing away the lungheat and moisturizing, clear liver and improve vision；Medicine
Reason experiments have shown that, mulberry leaf have antibacterial, diuresis, decompression the effects of.
Kiss-me: cold in nature, mildly bitter flavor, distributed in lung channel, stomach meridian have the effect of wind-dispelling, heat-clearing, blood-cleaning detoxifying；Pharmacological testing
Show that kiss-me has different degrees of inhibition to proteus, typhoid bacillus, shigella dysenteriae, staphylococcus aureus, Pseudomonas aeruginosa
Effect has heart tonifying, diuresis.
Cortex Magnoliae Officinalis: warm-natured, bitter, pungent, converge to the spleen channel, stomach meridian, lung channel, large intestine channel, the function with eliminating dampness dissolving phlegm, lower gas removes full
Effect；Pharmacological testing shows that Cortex Magnoliae Officinalis has the function of of flaccid muscles, antiulcer, there is significant central inhibitory action, and blood pressure lowering resists
Pathogenic microorganism, it is antitumor, the effects of flowing there are also antiplatelet and inhibition intracellular Ca2+.
Radix Glycyrrhizae: mild-natured, sweet in flavor, thoughts of returning home warp, stomach meridian, the spleen channel, lung channel, have invigorate the spleen and benefit qi, cough-relieving apophlegmatic, emergency analgesic therapy,
The effect of mediation property of medicine；Pharmacological testing shows that Radix Glycyrrhizae has a cortex hormone of aadrenaline effect, anti-inflammatory, antiulcer, antianaphylaxis,
Anticancer, antibacterial is antiviral, promotes pancreatic secretion, has inhibition in vitro intestines, adjusts immune function, kobadrin, anti-mutation, solution
Poison, it is anti-oxidant, the effects of diuresis.
The utility model has the advantages that the preferred multi-flavor natural traditional Chinese medicine raw material of the present invention, wherein schizonepeta, kiss-me expel pathogenic wind from the body surface, elscholtiza, old
Skin, Radix Glycyrrhizae temperature resolving sputum are wet, and loguat leaf, mulberry leaf clearing lung and relieving cough, campanulaceae, bulbus fritillariae cirrhosae are ventilatingd the lung and resolving phlegm, and carry medicine uplink, waxgourd peel, blackberry lily
Clearing heat, relieving sore-throat, campanulaceae, Cortex Magnoliae Officinalis one rise and one drop, dispersing and lowering lung-QI, relieving cough and reducing sputum, Radix Glycyrrhizae righting and medicine；All medicines share, total long memorial relieve heat
Heat, expel pathogenic wind from the body surface, be eliminating dampness and eliminating phlegm, clearing lung and relieving cough, eliminating phlegm and relieving asthma, clearing heat, relieving sore-throat function, can be used for treating influenza fever,
It has a headache and coughs, malasia, the diseases such as pharyngodynia with dryness are suitable for flu incubation period or sick hair phase, being capable of effective preventing cold later period
The symptoms such as caused cough, abscess of throat, curative for effect, safety is without side-effects.
Specific embodiment
In the following, technical solution of the present invention is described in detail by specific embodiment.
Embodiment 1
A kind of eliminating dampness Chinese medicine composition for treating cold cough proposed by the present invention, raw material includes: elscholtiza 5 by weight
Part, 15 parts of schizonepeta, 15 parts of waxgourd peel, 7 parts of dried orange peel, 12 parts of blackberry lily, 18 parts of bulbus fritillariae cirrhosae, 12 parts of campanulaceae, 10 parts of honeydew loguat leaf, mulberry
18 parts of leaf, 18 parts of kiss-me, 5 parts of Cortex Magnoliae Officinalis, 5 parts of radix glycyrrhizae preparata.
The invention also provides the preparation methods of the eliminating dampness Chinese medicine composition of above-mentioned treatment cold cough, including following step
It is rapid:
S1, schizonepeta, waxgourd peel, dried orange peel, campanulaceae, loguat leaf, mulberry leaf, Radix Glycyrrhizae are crushed, 2h is soaked in water in mixing, is decocted
It extracts 2 times, decocts extract 1h for the first time, decoct extract 1.5h for the second time, decocting extraction water consumption every time is medicinal material initial mass
6 times, filtered after decocting every time, merge filtrate twice, being concentrated under reduced pressure into relative density is 1.00 (50 DEG C of surveys) clear creams, and second is added
It is 45% that alcohol, which adjusts alcohol content, stands 20h, and filtering obtains refining liquid；
S2, elscholtiza, blackberry lily, bulbus fritillariae cirrhosae, kiss-me, Cortex Magnoliae Officinalis are crushed, mixing is added 70% ethanol solution and impregnates 1h, so
Diacolation is carried out using 4 times of medicinal material initial weight of 65% ethanol solution afterwards, the diacolation time is 7h, collects percolate；
S3, refining liquid and percolate are mixed, recycles ethyl alcohol, be concentrated under reduced pressure, spray drying obtains major ingredient；
S4, polyethylene glycol, talcum powder, magnesium stearate, cornstarch are added into major ingredient, by the routine of galenic pharmacy capsule
Capsule is made in technique.
Embodiment 2
A kind of eliminating dampness Chinese medicine composition for treating cold cough proposed by the present invention, raw material includes: elscholtiza by weight
12 parts, 7 parts of schizonepeta, 25 parts of waxgourd peel, 15 parts of dried orange peel, 5 parts of blackberry lily, 10 parts of bulbus fritillariae cirrhosae, 5 parts of campanulaceae, 18 parts of honeydew loguat leaf, mulberry
10 parts of leaf, 10 parts of kiss-me, 12 parts of Cortex Magnoliae Officinalis, 12 parts of radix glycyrrhizae preparata.
The invention also provides the preparation methods of the eliminating dampness Chinese medicine composition of above-mentioned treatment cold cough, including following step
It is rapid:
S1, schizonepeta, waxgourd peel, dried orange peel, campanulaceae, loguat leaf, mulberry leaf, Radix Glycyrrhizae are crushed, 4h is soaked in water in mixing, is decocted
It extracts 2 times, decocts extract 3h for the first time, decoct extract 1.5h for the second time, decocting extraction water consumption every time is medicinal material initial mass
10 times, filtered after decocting every time, merge filtrate twice, being concentrated under reduced pressure into relative density is 1.03 (50 DEG C of surveys) clear creams, is added
It is 55% that ethyl alcohol, which adjusts alcohol content, stands 26h, and filtering obtains refining liquid；
S2, elscholtiza, blackberry lily, bulbus fritillariae cirrhosae, kiss-me, Cortex Magnoliae Officinalis are crushed, mixing is added 70% ethanol solution and impregnates 2h, so
Diacolation is carried out using 6 times of medicinal material initial weight of 70% ethanol solution afterwards, the diacolation time is 10h, collects percolate；
S3, refining liquid and percolate are mixed, recycles ethyl alcohol, be concentrated under reduced pressure, spray drying obtains major ingredient；
S4, povidone, talcum powder, magnesium stearate, microcrystalline cellulose are added into major ingredient, by the conventional work of galenic pharmacy tablet
Skill is prepared into tablet.
Embodiment 3
A kind of eliminating dampness Chinese medicine composition for treating cold cough proposed by the present invention, raw material includes: elscholtiza 8 by weight
Part, 10 parts of schizonepeta, 20 parts of waxgourd peel, 12 parts of dried orange peel, 10 parts of blackberry lily, 16 parts of bulbus fritillariae cirrhosae, 10 parts of campanulaceae, 13 parts of honeydew loguat leaf,
16 parts of mulberry leaf, 15 parts of kiss-me, 8 parts of Cortex Magnoliae Officinalis, 10 parts of radix glycyrrhizae preparata.
The invention also provides the preparation methods of the eliminating dampness Chinese medicine composition of above-mentioned treatment cold cough, including following step
It is rapid:
S1, schizonepeta, waxgourd peel, dried orange peel, campanulaceae, loguat leaf, mulberry leaf, Radix Glycyrrhizae are crushed, 2.5h is soaked in water in mixing, is decocted
Extraction 2 times is boiled, first time, which decocts, extracts 2h, and water consumption is 8 times of medicinal material initial mass, and 1h, water consumption are extracted in second of decoction
It is 6 times of medicinal material initial mass, is filtered after decocting every time, merge filtrate twice, being concentrated under reduced pressure into relative density is 1.01 (50 DEG C
Survey) clear cream, it is 48% that ethyl alcohol, which is added, and adjusts alcohol content, stands 22h, filtering obtains refining liquid；
S2, elscholtiza, blackberry lily, bulbus fritillariae cirrhosae, kiss-me, Cortex Magnoliae Officinalis being crushed, mixing is added 70% ethanol solution and impregnates 1.5h,
Then diacolation is carried out using 4.5 times of medicinal material initial weight of 65% ethanol solution, the diacolation time is 8h, collects percolate；
S3, refining liquid and percolate are mixed, recycles ethyl alcohol, be concentrated under reduced pressure, spray drying obtains major ingredient；
S4,40 parts of sucrose, 15 parts of cyclodextrin are added into major ingredient, mixing adds appropriate polyethylene glycol, by galenic pharmacy
The common process of granula, wet granulation is to get granule.
Embodiment 4
A kind of eliminating dampness Chinese medicine composition for treating cold cough proposed by the present invention, raw material includes: elscholtiza 7 by weight
Part, 12 parts of schizonepeta, 22 parts of waxgourd peel, 10 parts of dried orange peel, 7 parts of blackberry lily, 15 parts of bulbus fritillariae cirrhosae, 8 parts of campanulaceae, 15 parts of honeydew loguat leaf, mulberry
15 parts of leaf, 12 parts of kiss-me, 10 parts of Cortex Magnoliae Officinalis, 8 parts of radix glycyrrhizae preparata.
The invention also provides the preparation methods of the eliminating dampness Chinese medicine composition of above-mentioned treatment cold cough, including following step
It is rapid:
S1, schizonepeta, waxgourd peel, dried orange peel, campanulaceae, loguat leaf, mulberry leaf, Radix Glycyrrhizae are crushed, 3h is soaked in water in mixing, is decocted
It extracts 2 times, first time, which decocts, extracts 2.5h, and water consumption is 8 times of medicinal material initial mass, and 1h, water consumption are extracted in second of decoction
It is 6 times of medicinal material initial mass, is filtered after decocting every time, merge filtrate twice, being concentrated under reduced pressure into relative density is 1.02 (50 DEG C
Survey) clear cream, it is 50% that ethyl alcohol, which is added, and adjusts alcohol content, is stood for 24 hours, filtering obtains refining liquid；
S2, elscholtiza, blackberry lily, bulbus fritillariae cirrhosae, kiss-me, Cortex Magnoliae Officinalis are crushed, mixing is added 70% ethanol solution and impregnates 2h, so
Diacolation is carried out using 5 times of medicinal material initial weight of 70% ethanol solution afterwards, the diacolation time is 9h, collects percolate；
S3, refining liquid and percolate are mixed, recycles ethyl alcohol, be concentrated under reduced pressure, spray drying obtains major ingredient；
S4,40 parts of sucrose, 15 parts of cyclodextrin are added into major ingredient, mixing adds appropriate polyethylene glycol, by galenic pharmacy
The common process of granula, wet granulation is to get granule.
Detection and clinical case by drug effect find that the Chinese medicine composition effect in embodiment 4 is best.
The eliminating dampness Chinese medicine composition for the treatment of cold cough prepared by the present invention is used for influenza cough.
1, case selection: selecting influenza cough patients 180 accepted for medical treatment, and patient age is 5 to 60 years old, and the course of disease is
1-14 days, mostly with the diseases such as runny nose, headache, cough, sore throat, out of strength, meet the diagnostic criteria of influenza cough, it can
To be diagnosed as influenza cough.It is classified as 2 groups, experimental group and control group, every group of 90 people, two groups there was no significant difference.
2, medicament selection: experimental group takes the eliminating dampness Chinese traditional medicine composition of the treatment cold cough prepared in the embodiment of the present invention 4
Object, 3g/ bags, boiled water is taken after mixing it with water, 1 bag every time below 12 one full year of life, three times per day, 12 it is more than one full year of life once 2 bags, three times per day；Control
Group takes Lian Huaqing pest particle, and boiled water is taken after mixing it with water, 12 one full year of life with 3g next time, 3 times a day, 12 one full year of life with last 6g, one day 3
It is secondary.3 days are 1 course for the treatment of, and duration of medication avoids drink raw food, scorching food, continuously take 1-2 course for the treatment of observation curative effect.
3, efficacy determination:
(1) cure: body temperature is normal, and cold cough symptom disappears, and blood routine examination is normal.
(2) improve: body temperature is normal, and the symptoms were significantly improved for cold cough, and blood routine examination index is close to normally.
(3) invalid: cold cough symptom is not improved or aggravates.
4, result:
| Healing/people | Improvement/people | In vain/people | Effective percentage/% | |
| Experimental group | 77 | 12 | 1 | 98.9 |
| Control group | 72 | 15 | 3 | 96.7 |
Through clinical treatment, controlled observation is found out, the eliminating dampness Chinese medicine composition for the treatment of cold cough of the invention is for prevalence
Property cold cough, definite effect do not find any toxic side effect in treatment.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (10)
1. a kind of eliminating dampness Chinese medicine composition for treating cold cough, which is characterized in that its raw material includes: elscholtiza 5-12 by weight
Part, 7-15 parts of schizonepeta, 15-25 parts of waxgourd peel, 7-15 parts of dried orange peel, 5-12 parts of blackberry lily, 10-18 parts of bulbus fritillariae cirrhosae, 5-12 parts of campanulaceae, Pi
10-18 parts of rake leaf, 10-18 parts of mulberry leaf, 10-18 parts of kiss-me, 5-12 parts of Cortex Magnoliae Officinalis, 5-12 parts of Radix Glycyrrhizae.
2. the eliminating dampness Chinese medicine composition for the treatment of cold cough according to claim 1, which is characterized in that the loguat leaf is
Honeydew loguat leaf.
3. the eliminating dampness Chinese medicine composition for the treatment of cold cough according to claim 1, which is characterized in that the Radix Glycyrrhizae is toast
Radix Glycyrrhizae.
4. the eliminating dampness Chinese medicine composition for the treatment of cold cough according to claim 1, which is characterized in that the Chinese traditional medicine composition
Object is tablet, granule, capsule, pill or oral solution.
5. a kind of preparation method of the eliminating dampness Chinese medicine composition based on the described in any item treatment cold coughs of claim 1-4,
Characterized by comprising the following steps:
S1, schizonepeta, waxgourd peel, dried orange peel, campanulaceae, loguat leaf, mulberry leaf, Radix Glycyrrhizae being crushed, mixing is soaked in water, and it decocts and extracts, mistake
Filter concentrates filtrate to clear cream, and it is 45-55% that ethyl alcohol, which is added, and adjusts alcohol content, stands, filtering obtains refining liquid；
S2, elscholtiza, blackberry lily, bulbus fritillariae cirrhosae, kiss-me, Cortex Magnoliae Officinalis are crushed, mixing is added 70% ethanol solution dipping, then uses
65-70% ethanol solution carries out diacolation, collects percolate；
S3, refining liquid and percolate are mixed, recycles ethyl alcohol, be concentrated under reduced pressure, spray drying obtains major ingredient；
S4, pharmaceutically acceptable auxiliary material is added into major ingredient, preparation is made according to a conventional method.
6. the preparation method of the eliminating dampness Chinese medicine composition for the treatment of cold cough according to claim 5, which is characterized in that S1
In, 2-4h is soaked in water, extraction 2 times is decocted, decocts extract 1-3h for the first time, 0.5-1.5h is extracted in second of decoction, is decocted every time
Boil 6-10 times for extracting water consumption as medicinal material initial mass.
7. the preparation method of the eliminating dampness Chinese medicine composition for the treatment of cold cough according to claim 5, which is characterized in that S1
In, concentrate filtrate to the clear cream that relative density is 1.00-1.03.
8. the preparation method of the eliminating dampness Chinese medicine composition for the treatment of cold cough according to claim 5, which is characterized in that S1
In, stand 20-26h.
9. the preparation method of the eliminating dampness Chinese medicine composition for the treatment of cold cough according to claim 5, which is characterized in that S2
In, 70% ethanol solution is added and impregnates 1-2h.
10. the preparation method of the eliminating dampness Chinese medicine composition for the treatment of cold cough according to claim 5, which is characterized in that
In S2, diacolation is 4-6 times of medicinal material initial weight with the dosage of 65-70% ethanol solution, and the diacolation time is 7-10h.
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| CN114191479A (en) * | 2021-11-23 | 2022-03-18 | 安徽省双辉生物科技有限公司 | Traditional Chinese medicine decoction pieces for clearing heat and removing toxicity based on liquorice and preparation method thereof |
| CN115040628A (en) * | 2022-07-21 | 2022-09-13 | 李庆梅 | Traditional Chinese medicine composition for clearing away heat and toxic materials and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114191479A (en) * | 2021-11-23 | 2022-03-18 | 安徽省双辉生物科技有限公司 | Traditional Chinese medicine decoction pieces for clearing heat and removing toxicity based on liquorice and preparation method thereof |
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| CN115040628A (en) * | 2022-07-21 | 2022-09-13 | 李庆梅 | Traditional Chinese medicine composition for clearing away heat and toxic materials and preparation method thereof |
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Application publication date: 20190917 |