CN104507961B - 抗炎性肽及包含其的组合物 - Google Patents
抗炎性肽及包含其的组合物 Download PDFInfo
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- CN104507961B CN104507961B CN201380036618.7A CN201380036618A CN104507961B CN 104507961 B CN104507961 B CN 104507961B CN 201380036618 A CN201380036618 A CN 201380036618A CN 104507961 B CN104507961 B CN 104507961B
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- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
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| CN202310636408.7A Division CN116694597A (zh) | 2012-05-11 | 2013-03-15 | 具有抗炎活性的肽及其在制备抗炎组合物中的应用 |
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Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104507961B (zh) | 2012-05-11 | 2018-08-14 | 珍白斯凯尔有限公司 | 抗炎性肽及包含其的组合物 |
| EP2875826B1 (en) | 2012-05-11 | 2017-08-23 | KAEL-GemVax Co.,Ltd | Composition for preventing or treating sepsis |
| WO2014010971A1 (ko) * | 2012-07-11 | 2014-01-16 | 주식회사 카엘젬백스 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
| US20150125438A1 (en) | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
| EP2899201B1 (en) | 2012-09-19 | 2019-09-11 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| EP2899199B1 (en) | 2012-09-19 | 2019-07-03 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| TWI616530B (zh) * | 2012-09-19 | 2018-03-01 | 傑姆維克斯&凱爾有限公司 | 穿膜胜肽以及包含該胜肽之共軛物及組成物(一) |
| EP3736282B1 (en) | 2012-09-19 | 2023-06-21 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| KR102258864B1 (ko) | 2013-04-19 | 2021-06-01 | 주식회사 젬백스앤카엘 | 허혈성 손상 치료 및 예방용 조성물 |
| AU2014275610B2 (en) | 2013-06-07 | 2018-06-14 | Gemvax & Kael Co., Ltd. | Biological markers useful in cancer immunotherapy |
| ES2808076T3 (es) | 2013-06-21 | 2021-02-25 | Gemvax & Kael Co Ltd | Regulador de la secreción hormonal, composición que lo contiene y procedimiento para controlar la secreción hormonal mediante su uso |
| ES2773296T3 (es) | 2013-10-23 | 2020-07-10 | Gemvax & Kael Co Ltd | Composición para tratar y prevenir la hiperplasia prostática benigna |
| KR102359396B1 (ko) * | 2013-11-22 | 2022-02-08 | 주식회사 젬백스앤카엘 | 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
| WO2015088233A1 (ko) * | 2013-12-10 | 2015-06-18 | 주식회사 카엘젬백스 | 항산화 효과를 가지는 펩티드 및 이를 포함하는 조성물 |
| JP6367950B2 (ja) | 2013-12-17 | 2018-08-01 | ジェムバックス アンド カエル カンパニー,リミティド | 前立腺癌治療用組成物 |
| ES2908096T3 (es) * | 2014-04-11 | 2022-04-27 | Gemvax & Kael Co Ltd | Péptido con actividad inhibidora de la fibrosis y composición que lo contiene |
| WO2015167067A1 (ko) * | 2014-04-30 | 2015-11-05 | 주식회사 카엘젬백스 | 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법 |
| WO2015170790A1 (ko) * | 2014-05-09 | 2015-11-12 | 주식회사 카엘젬백스 | 허혈성 손상 치료 및 예방용 조성물 |
| KR102232319B1 (ko) * | 2014-05-09 | 2021-03-26 | 주식회사 젬백스앤카엘 | 텔로머라제 펩티드를 유효성분으로 포함하는 뇌혈관 질환 예방 또는 치료용 조성물 |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| US10835582B2 (en) | 2015-02-27 | 2020-11-17 | Gemvax & Kael Co. Ltd. | Peptide for preventing hearing loss, and composition comprising same |
| KR101662438B1 (ko) | 2015-04-07 | 2016-10-04 | 가톨릭대학교 산학협력단 | X형 구조의 dna를 유효성분으로 포함하는 아토피 피부염 예방 또는 치료용 조성물 |
| EP3288961B8 (en) * | 2015-04-27 | 2022-04-27 | MacKay Memorial Hospital | Short synthetic peptide for treating diseases and/or conditions related to angiogenesis |
| EP3305802B1 (en) | 2015-05-26 | 2021-05-12 | Gemvax & Kael Co., Ltd. | Anti-inflammatory, anti-fibrotic and wound-healing octapeptides and compositions containing the same |
| JP6923453B2 (ja) * | 2015-07-02 | 2021-08-18 | ジェムバックス アンド カエル カンパニー,リミティド | 抗ウイルス活性効能を有するペプチド及びこれを含む組成物 |
| CN105061573B (zh) * | 2015-07-20 | 2018-08-21 | 苏州大学 | 姚虻天然抗炎症多肽cecropin-TY1及其应用 |
| KR20180064434A (ko) * | 2015-11-03 | 2018-06-14 | 주식회사 젬백스앤카엘 | 신경세포 손실 예방 및 재생 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
| WO2017116138A1 (ko) * | 2015-12-28 | 2017-07-06 | 주식회사 젬백스앤카엘 | 멜라닌 억제 기능성 펩티드 및 이를 포함하는 조성물 |
| KR101897122B1 (ko) * | 2016-03-09 | 2018-09-10 | 주식회사 바이오펩 | 염증성 질환의 예방 또는 치료용 펩타이드 및 이의 용도 |
| EP3428178A4 (en) * | 2016-03-09 | 2019-09-04 | Bio Pep Co., Ltd. | PEPTIDE FOR THE PREVENTION OR TREATMENT OF INFLAMMATORY DISEASES AND USE THEREOF |
| US9943566B2 (en) | 2016-03-16 | 2018-04-17 | Geoffrey Brooks Consultants, Llc | NF-κB inhibitor composition for skin health |
| ES2949697T3 (es) * | 2016-04-07 | 2023-10-02 | Gemvax & Kael Co Ltd | Péptido que tiene efectos de aumento de la actividad telomerasa y de extensión de los telómeros, y composición que contienen el mismo |
| KR101831888B1 (ko) * | 2016-04-15 | 2018-04-16 | (주)케어젠 | 항염증 활성을 갖는 펩타이드 및 이의 용도 |
| WO2017183942A2 (ko) * | 2016-04-21 | 2017-10-26 | 주식회사 젬백스앤카엘 | 콜라겐 생성 증가 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
| WO2018014936A1 (en) * | 2016-07-18 | 2018-01-25 | Nuritas Limited | Topical compositions |
| KR102042600B1 (ko) * | 2018-02-13 | 2019-11-08 | 전북대학교산학협력단 | 항산화 및 항염증 활성을 갖는 홍갯지렁이 유래 신규 펩타이드 및 이의 이용 |
| MA52794A (fr) * | 2018-05-28 | 2021-04-14 | Jiangyin Usun Pharmaceutical Co Ltd | Nouvelle utilisation pharmaceutique |
| CN112824428B (zh) * | 2019-11-21 | 2022-08-16 | 上海医药工业研究院 | 一种治疗肺疾病的生物肽及其应用 |
| KR102354916B1 (ko) * | 2020-02-11 | 2022-01-26 | 주식회사 쓰리빅스 | 신규 펩타이드 3ps_i014 및 이의 용도 |
| KR102266613B1 (ko) * | 2020-09-21 | 2021-06-18 | 자안바이오 주식회사 | 항염증 활성을 갖는 신규한 펩티드 및 이의 용도 |
| KR102302984B1 (ko) * | 2021-06-16 | 2021-09-17 | 주식회사 쓰리빅스 | 염증성 피부 질환 예방 또는 치료용 약학조성물 |
| WO2022270478A1 (ja) * | 2021-06-21 | 2022-12-29 | 国立大学法人北海道大学 | 抗ウイルス剤 |
| CN113461776B (zh) * | 2021-07-08 | 2023-05-16 | 南京财经大学 | 一种具有预防及治疗肠炎功能的小肽及其应用 |
| US11724077B2 (en) * | 2021-07-28 | 2023-08-15 | Subhash Dhawan | Therapeutic swabs for treating upper respiratory infections |
| KR102736939B1 (ko) * | 2021-09-30 | 2024-12-03 | (주)케어젠 | 항염증 활성을 갖는 펩타이드 및 이의 용도 |
| KR102609822B1 (ko) * | 2021-10-05 | 2023-12-06 | (주)케어젠 | 항염증 활성을 갖는 펩타이드와 이의 용도 |
| CN114349821B (zh) * | 2021-12-08 | 2024-01-16 | 南方医科大学珠江医院 | 蛙皮抗氧化肽及其基因在制药和抗皱化妆品的应用 |
| KR102856378B1 (ko) | 2022-09-30 | 2025-09-08 | 주식회사 젬백스앤카엘 | 4r 타우병증의 치료 또는 예방용 펩티드 |
| AU2024285799A1 (en) * | 2023-06-08 | 2025-12-18 | Gemvax & Kael Co., Ltd. | Composition comprising gv1001 for preventing or treating periodontal diseases and disorders caused by periodontal diseases |
| EP4733310A1 (en) | 2023-06-23 | 2026-04-29 | Gemvax & Kael Co., Ltd. | Novel peptide and use thereof |
| CN116693612B (zh) * | 2023-06-28 | 2025-02-18 | 禾美生物科技(浙江)有限公司 | 一种环肽及其用途 |
| KR102800994B1 (ko) | 2023-11-06 | 2025-04-29 | 주식회사 엘지에너지솔루션 | 무음극 코팅층 및 이를 포함하는 전고체 전지 |
| CN117986337B (zh) * | 2024-02-02 | 2024-08-16 | 杭州御寿生物科技有限公司 | 一种提高免疫力的益生菌组合物以及在治疗疾病中的应用 |
| WO2026071839A1 (ko) * | 2024-09-30 | 2026-04-02 | 주식회사 젬백스앤카엘 | Gv1001 펩타이드를 포함하는 암세포의 cd47 발현 감소 및 대식세포의 식세포작용 증가용 조성물 및 이의 용도 |
| CN119320425B (zh) * | 2024-11-08 | 2025-08-05 | 深圳市第二人民医院(深圳市转化医学研究院) | 多肽aamp及其在镇痛抗炎中的应用 |
| CN119552212B (zh) * | 2025-01-26 | 2025-04-25 | 杭州康源食品科技有限公司 | 一种具有降尿酸活性的三肽lfp及其应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1291231A (zh) * | 1996-10-01 | 2001-04-11 | 杰龙公司 | 人类的端粒酶催化亚单位 |
| WO2010003520A3 (en) * | 2008-06-16 | 2010-07-15 | Genovax S.R.L. | Anti-tumor immunotherapy |
| WO2011101173A1 (en) * | 2010-02-16 | 2011-08-25 | Oslo University Hospital Hf | Polypeptides |
Family Cites Families (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR930001915B1 (ko) | 1990-06-27 | 1993-03-20 | 포항종합제철 주식회사 | 저온 소결 압전요업재료 제조방법 |
| HU207799B (en) | 1991-07-24 | 1993-06-28 | Beres Export Import Rt | Process for producing pharmaceutical composition for influencing the reticuloendothelial system, for treating chronic pain symptomes of degenerative locomotor disorders or tumors, and for treating mucoviscidosis |
| EP0930876B2 (en) | 1996-07-22 | 2010-07-07 | Renovo Limited | Use of compounds that promote oestrogenic activity for acclerating the healing of skin wounds |
| US6610839B1 (en) * | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| US6475789B1 (en) * | 1996-10-01 | 2002-11-05 | University Technology Corporation | Human telomerase catalytic subunit: diagnostic and therapeutic methods |
| WO1998051329A1 (en) | 1997-05-15 | 1998-11-19 | Chugai Seiyaku Kabushiki Kaisha | Cachexia remedy |
| KR100581990B1 (ko) | 1997-07-01 | 2006-05-23 | 캄비아 바이오시스템즈 엘엘씨 | 척추 동물 텔로머라제 유전자 및 단백질과 이의 용도 |
| US7030211B1 (en) * | 1998-07-08 | 2006-04-18 | Gemvax As | Antigenic peptides derived from telomerase |
| US6378526B1 (en) | 1998-08-03 | 2002-04-30 | Insite Vision, Incorporated | Methods of ophthalmic administration |
| IL132406A0 (en) | 1998-10-21 | 2001-03-19 | Pfizer Prod Inc | Treatment of bph with cgmp elevators |
| US6815426B2 (en) | 2001-02-16 | 2004-11-09 | E. I. Du Pont De Nemours And Company | Angiogenesis-inhibitory tripeptides, compositions and their methods of use |
| US6967211B2 (en) | 2001-04-10 | 2005-11-22 | Nippon Shinyaku Co. Ltd. | Remedial agent for chronic articular rheumatism |
| BR0210904A (pt) | 2001-05-16 | 2005-08-16 | Yeda Res & Dev | Uso de inibidores de il-18 para o tratamento ou prevenção de sepse |
| US20030143228A1 (en) | 2001-10-29 | 2003-07-31 | Baylor College Of Medicine | Human telomerase reverse transcriptase as a class-II restricted tumor-associated antigen |
| US7786084B2 (en) | 2001-12-21 | 2010-08-31 | Biotempt B.V. | Treatment of burns |
| WO2003064447A2 (en) * | 2002-01-29 | 2003-08-07 | Posco | Immune-modulating peptide |
| AU2003240754B2 (en) | 2002-04-10 | 2009-02-26 | Merck Serono Sa | Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis |
| KR20050020987A (ko) | 2002-06-12 | 2005-03-04 | 바이오겐 아이덱 엠에이 인코포레이티드 | 아데노신 수용체 길항제를 사용하여 허혈 재관류 손상을치료하는 방법 |
| WO2005000227A2 (en) | 2003-06-06 | 2005-01-06 | Intermune, Inc. | Methods of treating tnf-mediated disorders |
| EP1648490A2 (en) | 2003-06-25 | 2006-04-26 | Canbas Co., Ltd. | Peptides and peptidomimetics having immune-modulating, anti-inflammatory, and anti-viral activity |
| KR20050040517A (ko) | 2003-10-29 | 2005-05-03 | 주식회사 오리엔트 | 허혈성 질환에 대한 저항성을 나타내는 형질전환 생쥐 |
| ES2258694T3 (es) | 2003-11-11 | 2006-09-01 | Mattern, Udo | Sistema de administracion de liberacion controlada de hormonas sexuales para aplicaciones nasales. |
| GB0426146D0 (en) | 2004-11-29 | 2004-12-29 | Bioxell Spa | Therapeutic peptides and method |
| CA2646131C (en) | 2005-03-21 | 2018-09-04 | Vicus Therapeutics Spe 1, Llc | Compositions and methods for ameliorating cachexia |
| WO2007061029A1 (ja) | 2005-11-25 | 2007-05-31 | Keio University | 前立腺癌治療剤 |
| EP1968643A2 (en) | 2005-12-16 | 2008-09-17 | Diatos | Cell penetrating peptide conjugates for delivering of nucleic acids into a cell |
| EP1969141A4 (en) * | 2005-12-23 | 2009-01-21 | Sienna Cancer Diagnostics Ltd | TEST FOR DETECTING TELOMERASE ACTIVITY |
| JP5295785B2 (ja) | 2006-02-20 | 2013-09-18 | エファ・ユニバーシティ・インダストリー・コラボレイション・ファウンデイション | 細胞膜透過性ペプチド |
| JP2009544688A (ja) | 2006-07-24 | 2009-12-17 | フォーヒューマンテック カンパニー リミテッド | 虚血性疾患の緩和及び治療のための医薬組成物並びにそれを伝達するための方法 |
| EP2837636B1 (en) | 2007-01-29 | 2018-04-11 | Procell Therapeutics Inc. | Novel macromolecule transduction domains and methods for identification and uses thereof |
| WO2009006439A1 (en) | 2007-06-29 | 2009-01-08 | Correlogic Systems, Inc. | Predictive markers for ovarian cancer |
| CA2695374A1 (en) | 2007-08-15 | 2009-02-19 | Amunix, Inc. | Compositions and methods for modifying properties of biologically active polypeptides |
| WO2009025871A1 (en) * | 2007-08-23 | 2009-02-26 | University Of Medicine And Dentistry Of Nj | Telomerase reverse transcriptase variant |
| WO2009054996A2 (en) | 2007-10-25 | 2009-04-30 | Genelux Corporation | Systems and methods for viral therapy |
| GB2455539B (en) | 2007-12-12 | 2012-01-18 | Cambridge Entpr Ltd | Anti-inflammatory compositions and combinations |
| TW200946541A (en) | 2008-03-27 | 2009-11-16 | Idenix Pharmaceuticals Inc | Solid forms of an anti-HIV phosphoindole compound |
| US8252282B2 (en) | 2008-06-19 | 2012-08-28 | University Of Medicine & Dentistry Of New Jersey | Nuclear telomerase reverse transcriptase variant |
| ES2334315B1 (es) | 2008-07-29 | 2011-02-28 | Universitat Pompeu Fabra | Peptidos con capacidad de penetracion celular y sus usos. |
| CA2734487A1 (en) | 2008-08-20 | 2010-02-25 | Southern Research Institute | Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections |
| JP5337809B2 (ja) | 2008-09-22 | 2013-11-06 | 日清ファルマ株式会社 | 抗炎症性ペプチド |
| WO2010037395A2 (en) | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
| KR101169030B1 (ko) | 2009-01-21 | 2012-07-26 | 애니젠 주식회사 | 신규한 세포막 투과 도메인 및 이를 포함하는 세포내 전달 시스템 |
| CN102405183B (zh) | 2009-04-20 | 2014-08-06 | 奥蒂斯电梯公司 | 用于乘客传送器的扶栏和盖板安装组件 |
| WO2010128807A2 (ko) | 2009-05-07 | 2010-11-11 | (주)문엔제이 | 신경손상 및 신경질환 예방 또는 치료용 약학조성물 |
| EP2251028A1 (en) | 2009-05-12 | 2010-11-17 | Biocompatibles Uk Ltd. | Treatment of eye diseases using encapsulated cells encoding and secreting an anti-angiogenic factor and/or a neuroprotective factor |
| US7928067B2 (en) | 2009-05-14 | 2011-04-19 | Ischemix Llc | Compositions and methods for treating ischemia and ischemia-reperfusion injury |
| AU2010250452B2 (en) | 2009-05-20 | 2014-06-05 | Toray Industries, Inc. | Cell membrane-permeable peptides |
| KR20110057049A (ko) | 2009-11-23 | 2011-05-31 | 박의신 | 기능성 전립선염 치료제 |
| KR20110062943A (ko) | 2009-12-04 | 2011-06-10 | 주식회사종근당 | 퀴나졸린 유도체를 유효성분으로 하는 전립선 비대증 예방 또는 치료제 |
| NO2524039T3 (enExample) | 2010-01-11 | 2018-04-28 | ||
| FR2960542B1 (fr) | 2010-05-27 | 2012-08-17 | Esther Suzy Arlette Fellous | Peptide en tant que medicament, en particulier pour le traitement du cancer |
| KR101263212B1 (ko) | 2010-05-28 | 2013-05-10 | 성신여자대학교 산학협력단 | 신규한 세포막 투과성 펩타이드 및 그의 용도 |
| WO2011150494A1 (en) | 2010-05-30 | 2011-12-08 | The Governing Council Of The University Of Toronto | Mitochondrial penetrating peptides as carriers for anticancer compounds |
| KR101388372B1 (ko) | 2010-06-11 | 2014-04-23 | 한국화학연구원 | 청각보호 작용을 하는 신규 화합물 |
| KR101348284B1 (ko) | 2010-09-09 | 2014-01-03 | 주식회사 나이벡 | 인간 유래 세포 투과성 펩타이드와 생리활성 펩타이드 결합체 및 그 용도 |
| US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
| KR20120121196A (ko) | 2011-04-26 | 2012-11-05 | 주식회사 글루칸 | 관절염 치료제 |
| KR101284772B1 (ko) | 2011-05-24 | 2013-07-17 | 정종문 | 항염증, 진통효과를 가지는 기능성 식품 조성물 |
| KR20120133661A (ko) | 2011-05-31 | 2012-12-11 | 주식회사 바이오포트코리아 | 아스타잔틴을 포함하는 항염증제 |
| KR101288053B1 (ko) | 2011-07-04 | 2013-07-23 | 동국대학교 산학협력단 | 필발 추출물을 유효성분으로 포함하는 내이손상 예방 및 치료용 조성물 |
| KR101361445B1 (ko) | 2011-12-26 | 2014-02-12 | 성균관대학교산학협력단 | 펩타이드, 5-플루오로우라실, 및 성숙수지상세포를 포함하는 암 치료용 약학적 조성물 |
| SG11201404570WA (en) | 2012-02-10 | 2014-11-27 | Hakushinkouseikai Foundation | Proliferating agent for monocyte, culture medium for proliferating monocyte, method for producing monocyte, method for producing dendritic cell, and method for producing dendritic cell vaccine |
| WO2013135266A1 (en) | 2012-03-12 | 2013-09-19 | Gemvax As | Treatment of non-small cell lung carcinoma by active immunotherapy |
| CN104507961B (zh) | 2012-05-11 | 2018-08-14 | 珍白斯凯尔有限公司 | 抗炎性肽及包含其的组合物 |
| EP2875826B1 (en) | 2012-05-11 | 2017-08-23 | KAEL-GemVax Co.,Ltd | Composition for preventing or treating sepsis |
| WO2014010971A1 (ko) | 2012-07-11 | 2014-01-16 | 주식회사 카엘젬백스 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
| US20150125438A1 (en) | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
| EP3736282B1 (en) | 2012-09-19 | 2023-06-21 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| KR102038487B1 (ko) | 2012-09-19 | 2019-10-30 | 주식회사 젬백스앤카엘 | 텔로머라제 펩티드를 포함하는 항균 또는 항진균용 조성물 |
| EP2899201B1 (en) | 2012-09-19 | 2019-09-11 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| EP2899199B1 (en) | 2012-09-19 | 2019-07-03 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| KR20140104288A (ko) | 2013-02-20 | 2014-08-28 | 주식회사 카엘젬백스 | Tnf-알파 저해제 |
| US10525075B2 (en) | 2013-02-22 | 2020-01-07 | The Board Of Trustees Of The Leland Stanford Junior University | Compounds, compositions, methods, and kits relating to telomere extension |
| KR102258864B1 (ko) | 2013-04-19 | 2021-06-01 | 주식회사 젬백스앤카엘 | 허혈성 손상 치료 및 예방용 조성물 |
| AU2014275610B2 (en) | 2013-06-07 | 2018-06-14 | Gemvax & Kael Co., Ltd. | Biological markers useful in cancer immunotherapy |
| ES2808076T3 (es) | 2013-06-21 | 2021-02-25 | Gemvax & Kael Co Ltd | Regulador de la secreción hormonal, composición que lo contiene y procedimiento para controlar la secreción hormonal mediante su uso |
| EP3020724A4 (en) | 2013-07-12 | 2017-01-18 | Gemvax & Kael Co., Ltd. | Cell-penetrating peptide and conjugate comprising same |
| ES2773296T3 (es) | 2013-10-23 | 2020-07-10 | Gemvax & Kael Co Ltd | Composición para tratar y prevenir la hiperplasia prostática benigna |
| KR102359396B1 (ko) | 2013-11-22 | 2022-02-08 | 주식회사 젬백스앤카엘 | 혈관 신생 억제 활성을 가지는 펩티드 및 이를 포함하는 조성물 |
| JP6367950B2 (ja) | 2013-12-17 | 2018-08-01 | ジェムバックス アンド カエル カンパニー,リミティド | 前立腺癌治療用組成物 |
| ES2908096T3 (es) | 2014-04-11 | 2022-04-27 | Gemvax & Kael Co Ltd | Péptido con actividad inhibidora de la fibrosis y composición que lo contiene |
| WO2015167067A1 (ko) | 2014-04-30 | 2015-11-05 | 주식회사 카엘젬백스 | 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법 |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| US10835582B2 (en) | 2015-02-27 | 2020-11-17 | Gemvax & Kael Co. Ltd. | Peptide for preventing hearing loss, and composition comprising same |
| EP3305802B1 (en) | 2015-05-26 | 2021-05-12 | Gemvax & Kael Co., Ltd. | Anti-inflammatory, anti-fibrotic and wound-healing octapeptides and compositions containing the same |
| US20170112941A1 (en) | 2015-10-13 | 2017-04-27 | Symic Ip, Llc | Ve-cadherin binding bioconjugate |
| KR20180064434A (ko) | 2015-11-03 | 2018-06-14 | 주식회사 젬백스앤카엘 | 신경세포 손실 예방 및 재생 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
| KR20170054310A (ko) | 2015-11-09 | 2017-05-17 | 주식회사 젬백스앤카엘 | 텔로머라제 유래 펩티드를 포함하는 수지상세포 치료제 및 면역 치료제, 및 이를 사용하는 치료방법 |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1291231A (zh) * | 1996-10-01 | 2001-04-11 | 杰龙公司 | 人类的端粒酶催化亚单位 |
| WO2010003520A3 (en) * | 2008-06-16 | 2010-07-15 | Genovax S.R.L. | Anti-tumor immunotherapy |
| WO2011101173A1 (en) * | 2010-02-16 | 2011-08-25 | Oslo University Hospital Hf | Polypeptides |
Non-Patent Citations (1)
| Title |
|---|
| Telomerase peptide vaccination of patients with non-resectable pancreatic cancer: a dose escalating phase I/II study;SL Bernhardt et al.;《British Journal of Cancer》;20061231;第95卷(第11期);1474-1482 * |
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