CN104431607A - Feed capable of preventing and treating infectious serositis of duck - Google Patents

Abstract

The invention provides a feed capable of preventing and treating infectious serositis of duck. The raw materials of the feed comprise corn, wheat, corn protein powder, pea protein powder, calcium hydrophosphate, table salt, threonine, methionine, liquid phytase, vitamin premix, mineral premix, and traditional Chinese medicine powder for preventing and treating infectious serositis of duck. The feed containing the traditional Chinese medicine powder for preventing and treating infectious serositis of duck is good in curative effect, safe and reliable, free from hazard residues, and not liable to generate medicine tolerance.

Description

The feed of control duck infectious serositis

Technical field

The present invention relates to field of feed, particularly relate to a kind of feed preventing and treating duck infectious serositis.

 

Background technology

Duck infectious serositis is a kind of acute septic infectious disease being caused duck by Mo Shi bacillus in pest of duck, the duckling of main harm 1 ~ 5 week age (especially 2 ~ 3 week age), all can occur throughout the year, cross cold, overheated and severe feeding environment and all easily cause morbidity, support duck industry to the world and cause huge economic loss.

This disease was reported by Hendrickson and Hibert in the U.S. early than 1932, and from the duck that dies of illness, be separated to cause of disease; Nineteen fifty-five, Dougherty carried out pathological research to this disease, found that " scrositis " is very important pathological characters, therefore called after duck infectious serositis.Subsequently, Canada, Spain, Singapore, Thailand, Norway, Australia, Japan etc. report in succession has this disease popular, nearly all has this disease to occur so far all over the world.

This disease was equaled within 1975, to propose the existence of this disease in China first by Kuang Ronglu in China, and had made a definite diagnosis the existence of this disease in Guangdong and popular in 1981; Guo Yupu equals the popular of this disease in nineteen eighty-two reported first Beijing commodity duck, and is separated to cause of disease.

Because in pest of duck, the serotype of Mo Shi bacillus is more, resistant rate high and extensively, cross resistance is many, after the course for the treatment of of a kind of drug use, its effect reduces or greatly without much effects.Vaccine, medical treatment effect are still undesirable, therefore find safe and reliable, become problem in the urgent need to address in this disease current treatment without hazard residue, the medicine that not easily produces drug resistance.

It is high that Chinese medicine has overall curative effect, not easily produce the advantages such as drug resistance, have significant inhibitory action to the growth and reproduction of the cause of disease such as bacterium, virus, even reach the pharmacological effect killing cause of disease, and can regulate, promote the immunologic function of body, there is the effect of non-specific resisting pathogenic microbes.Traditional Chinese veterinary medicine thinks that this disease belongs to " warm disease, acute infantile convulsions " category, clinically with heating, twitch, coma for main symptom, sick position is in conscience, and based on heat symptom-complex, real example, therefore principle of reatment be " clearing heat and detoxicating, to relieve dizziness, high fever, infantile convulsions, epilepsy, etc. and only shy, eliminate phlegm for resuscitation ".The present invention proposes under this principle, prepared Chinese medicinal powder good effect, safe and reliable, without hazard residue, not easily produce drug resistance.

 

Summary of the invention

Technical problem to be solved by this invention is to provide a kind of for preventing and treating the Chinese medicinal powder of duck infectious serositis and comprise the feed of this Chinese medicinal powder, its good effect, safe and reliable, without hazard residue, not easily produce drug resistance.

For solving the problems of the technologies described above, the invention provides a kind of feed preventing and treating duck infectious serositis, its raw material comprises corn, wheat, corn protein powder, Fed Protein Powder of Pea Insteal, calcium monohydrogen phosphate, salt, threonine, methionine, liquid phytase, vitamin premix, mineral substance premix and the Chinese medicinal powder for preventing and treating duck infectious serositis.

Wherein, in described duck feed, the weight of each raw material is respectively corn 2.5kg ~ 3.5kg, wheat 2kg ~ 3kg, corn protein powder 300g ~ 400g, Fed Protein Powder of Pea Insteal 100g ~ 200g, calcium monohydrogen phosphate 150g ~ 250g, salt 50g ~ 70g, threonine 20g ~ 30g, methionine 20g ~ 30g, liquid phytase 10g ~ 20g, vitamin premix 50g ~ 70g, mineral substance premix 50g ~ 70g and described Chinese medicinal powder 600g ~ 700g.

Wherein, in described duck feed, the weight of each raw material is respectively corn 3kg, wheat 2.5kg, corn protein powder 400g, Fed Protein Powder of Pea Insteal 200g, calcium monohydrogen phosphate 200g, salt 60g, threonine 20g, methionine 20g, liquid phytase 10g, vitamin premix 60g, mineral substance premix 60g and described Chinese medicinal powder 700g.

Wherein, the bulk drug of described Chinese medicinal powder comprises the radix paeoniae rubrathe, cassia twig, balloonflower root, franzenbach rhubarb root and rhizome, barrenwort, giant knotweed, cordate houttuynia, yncaria stem with hooks, Paper mulberry Fruit, Selaginella tamariscina, grass-leaved sweetflag, bush, sea-buckthorn, horse tooth are looked for, lycopodium calvatum, stringy stonecrop, bilobed grewia root stem and leaf, Shui Fengxian, pennywort and maidenhair.

Wherein, in described Chinese medicinal powder, the weight of each bulk drug is respectively radix paeoniae rubrathe 200g ~ 250g, cassia twig 180g ~ 220g, balloonflower root 150g ~ 190g, franzenbach rhubarb root and rhizome 120g ~ 160g, barrenwort 200g ~ 250g, giant knotweed 250g ~ 280g, cordate houttuynia 170g ~ 220g, yncaria stem with hooks 120g ~ 150g, Paper mulberry Fruit 160g ~ 200g, Selaginella tamariscina 100g ~ 150g, grass-leaved sweetflag 80g ~ 120g, bush 100g ~ 150g, sea-buckthorn 120g ~ 160g, horse tooth looks for 100g ~ 150g, lycopodium calvatum 120g ~ 170g, stringy stonecrop 110g ~ 150g, bilobed grewia root stem and leaf 80g ~ 120g, celestial 80g ~ the 120g of water phoenix, pennywort 120g ~ 160g and maidenhair 120g ~ 150g.

Wherein, in described Chinese medicinal powder, the weight of each bulk drug is respectively radix paeoniae rubrathe 210g ~ 230g, cassia twig 190g ~ 210g, balloonflower root 160g ~ 180g, franzenbach rhubarb root and rhizome 130g ~ 150g, barrenwort 220g ~ 240g, giant knotweed 260g ~ 270g, cordate houttuynia 190g ~ 200g, yncaria stem with hooks 130g ~ 140g, Paper mulberry Fruit 170g ~ 190g, Selaginella tamariscina 120g ~ 140g, grass-leaved sweetflag 90g ~ 110g, bush 120g ~ 140g, sea-buckthorn 130g ~ 150g, horse tooth looks for 120g ~ 140g, lycopodium calvatum 140g ~ 160g, stringy stonecrop 130g ~ 140g, bilobed grewia root stem and leaf 90g ~ 110g, celestial 90g ~ the 110g of water phoenix, pennywort 130g ~ 150g and maidenhair 130g ~ 140g.

Wherein, the preparation method of described Chinese medicinal powder is as follows:

The first step, get the radix paeoniae rubrathe, franzenbach rhubarb root and rhizome, barrenwort, giant knotweed, Paper mulberry Fruit, Selaginella tamariscina, bush, sea-buckthorn, lycopodium calvatum, bilobed grewia root stem and leaf and maidenhair, pulverize respectively, mix by above-mentioned weight, adding relative to the determining alcohol of mixture quality 3 ~ 5 times is subsequently 90% ~ 95% ethanolic solution, add hot reflux 2 ~ 4 hours, filter, obtain the first extract, it is 90% ~ 95% ethanolic solution that filter residue adds relative to the determining alcohol of its quality 2 ~ 5 times again, add hot reflux 1 ~ 2 hour, filter, obtain the second extract, extract is merged, reduced pressure concentration removing ethanol, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order,

Second step, pulverizes respectively by remaining components, mixes by above-mentioned weight, boiling three times, first time adds the water relative to mixture quality 10 ~ 12 times, and second and third time is the water of 8 ~ 10 times amount, each decoction 2 hours, collecting decoction, filter, concentrated except anhydrating, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order;

3rd step, the powder mixing after the ultramicro grinding obtain the first step and second step, adds the starch relative to mixed-powder twice quality, stirs, obtain Chinese medicinal powder.

Present invention also offers the preparation method of above-mentioned feed, it comprises:

The first step, prepares described Chinese medicinal powder;

Second step, gets all raw materials by weight, mixing, and drop into pulverizer and pulverize, grinding particle size is 20 ~ 40 orders;

3rd step, drop into granulator and granulate, pelleting temperature is 70 ~ 85 DEG C, makes its gelatinization degree reach 90%, obtains product.

The described first step is specially further:

A walks, get the radix paeoniae rubrathe, franzenbach rhubarb root and rhizome, barrenwort, giant knotweed, Paper mulberry Fruit, Selaginella tamariscina, bush, sea-buckthorn, lycopodium calvatum, bilobed grewia root stem and leaf and maidenhair, pulverize respectively, mix by above-mentioned weight, adding relative to the determining alcohol of mixture quality 3 ~ 5 times is subsequently 90% ~ 95% ethanolic solution, add hot reflux 2 ~ 4 hours, filter, obtain the first extract, it is 90% ~ 95% ethanolic solution that filter residue adds relative to the determining alcohol of its quality 2 ~ 5 times again, add hot reflux 1 ~ 2 hour, filter, obtain the second extract, extract is merged, reduced pressure concentration removing ethanol, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order,

B walks, and is pulverized respectively by remaining components, mixes by above-mentioned weight, boiling three times, first time adds the water relative to mixture quality 10 ~ 12 times, and second and third time is the water of 8 ~ 10 times amount, each decoction 2 hours, collecting decoction, filter, concentrated except anhydrating, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order;

C walks, and the powder mixing after the ultramicro grinding obtain a step and b step, adds the starch relative to mixed-powder twice quality, stir, obtain Chinese medicinal powder.

Beneficial effect of the present invention:

The invention provides a kind of for preventing and treating the Chinese medicinal powder of duck infectious serositis and comprise the feed of this Chinese medicinal powder, its good effect, safe and reliable, without hazard residue, not easily produce drug resistance.

 

Detailed description of the invention

The invention provides a kind of Chinese medicinal powder preventing and treating duck infectious serositis, its bulk drug comprise the radix paeoniae rubrathe, cassia twig, balloonflower root, franzenbach rhubarb root and rhizome, barrenwort, giant knotweed, cordate houttuynia, yncaria stem with hooks, Paper mulberry Fruit, Selaginella tamariscina, grass-leaved sweetflag, bush, sea-buckthorn, horse tooth are looked for, lycopodium calvatum, stringy stonecrop, bilobed grewia root stem and leaf, Shui Fengxian, pennywort and maidenhair.

Further preferably, described Chinese medicinal powder is only made up of above-mentioned raw materials medicine.

In described Chinese medicinal powder, the weight of each bulk drug is respectively radix paeoniae rubrathe 200g ~ 250g, cassia twig 180g ~ 220g, balloonflower root 150g ~ 190g, franzenbach rhubarb root and rhizome 120g ~ 160g, barrenwort 200g ~ 250g, giant knotweed 250g ~ 280g, cordate houttuynia 170g ~ 220g, yncaria stem with hooks 120g ~ 150g, Paper mulberry Fruit 160g ~ 200g, Selaginella tamariscina 100g ~ 150g, grass-leaved sweetflag 80g ~ 120g, bush 100g ~ 150g, sea-buckthorn 120g ~ 160g, horse tooth looks for 100g ~ 150g, lycopodium calvatum 120g ~ 170g, stringy stonecrop 110g ~ 150g, bilobed grewia root stem and leaf 80g ~ 120g, celestial 80g ~ the 120g of water phoenix, pennywort 120g ~ 160g and maidenhair 120g ~ 150g.

Further preferably, in described Chinese medicinal powder, the weight of each bulk drug is respectively radix paeoniae rubrathe 210g ~ 230g, cassia twig 190g ~ 210g, balloonflower root 160g ~ 180g, franzenbach rhubarb root and rhizome 130g ~ 150g, barrenwort 220g ~ 240g, giant knotweed 260g ~ 270g, cordate houttuynia 190g ~ 200g, yncaria stem with hooks 130g ~ 140g, Paper mulberry Fruit 170g ~ 190g, Selaginella tamariscina 120g ~ 140g, grass-leaved sweetflag 90g ~ 110g, bush 120g ~ 140g, sea-buckthorn 130g ~ 150g, horse tooth looks for 120g ~ 140g, lycopodium calvatum 140g ~ 160g, stringy stonecrop 130g ~ 140g, bilobed grewia root stem and leaf 90g ~ 110g, celestial 90g ~ the 110g of water phoenix, pennywort 130g ~ 150g and maidenhair 130g ~ 140g.

Further preferably, in described Chinese medicinal powder, the weight of each bulk drug is respectively radix paeoniae rubrathe 220g, cassia twig 200g, balloonflower root 170g, franzenbach rhubarb root and rhizome 140g, barrenwort 230g, giant knotweed 260g, cordate houttuynia 200g, yncaria stem with hooks 130g, Paper mulberry Fruit 180g, Selaginella tamariscina 130g, grass-leaved sweetflag 100g, bush 130g, sea-buckthorn 140g, horse tooth look for 130g, lycopodium calvatum 150g, stringy stonecrop 130g, bilobed grewia root stem and leaf 100g, water phoenix celestial 100g, pennywort 140g and maidenhair 130g.

The preparation method of described Chinese medicinal powder is as follows:

The first step, get the radix paeoniae rubrathe, franzenbach rhubarb root and rhizome, barrenwort, giant knotweed, Paper mulberry Fruit, Selaginella tamariscina, bush, sea-buckthorn, lycopodium calvatum, bilobed grewia root stem and leaf and maidenhair, pulverize respectively, mix by above-mentioned weight, adding relative to the determining alcohol of mixture quality 3 ~ 5 times is subsequently 90% ~ 95% ethanolic solution, add hot reflux 2 ~ 4 hours, filter, obtain the first extract, it is 90% ~ 95% ethanolic solution that filter residue adds relative to the determining alcohol of its quality 2 ~ 5 times again, add hot reflux 1 ~ 2 hour, filter, obtain the second extract, extract is merged, reduced pressure concentration removing ethanol, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order,

Second step, pulverizes respectively by remaining components, mixes by above-mentioned weight, boiling three times, first time adds the water relative to mixture quality 10 ~ 12 times, and second and third time is the water of 8 ~ 10 times amount, each decoction 2 hours, collecting decoction, filter, concentrated except anhydrating, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order;

3rd step, the powder mixing after the ultramicro grinding obtain the first step and second step, adds the starch relative to mixed-powder twice quality, stirs, obtain Chinese medicinal powder.

Each bulk drug pharmacology is as follows:

The radix paeoniae rubrathe: bitter, micro-hardship, returns Liver Channel, has purge the green, clearing heat and cooling blood, effect of stasis-dispelling and pain-killing, cure mainly the red eye, swell pain of high liver fire, have a dizzy spell, pain in chest and hypochondrium, and the hot tongue of body of warm heat disease heat invading xuefen is deep red, and macula is hemorrhage, and blood stasis is through closing; The haematemesis hematuria of the absurd row of burning hot flourishing urgent blood; The trip of women's blood-head is through too much; Various pain caused by blood retardance; The sore furuncle carbuncle of blood-head poison Sheng is swollen waits card.

Cassia twig: latin name cinnamomi ramulus, be the dry spray of canella Chinese cassia tree, taste is pungent, sweet, warm in nature, the thoughts of returning home, lung, urinary bladder channel, have sweating expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, help yang transforming qi, the effect of eliminating cold to stop pain, warming meridians and promoting circulation of qi, horizontal logical podomere, for illness that has not attacked the vital organs of the human body of catching cold, no matter have sweat, losslessly all can to apply, also for arthralgia due to wind-dampness, stomach cold stomachache, through closing, dysmenorrhoea, arthralgia due to wind-dampness, the cards such as shoulder arm podomere crymodynia, phlegm retention syndrome and bladder retaining, the heart is insufficiency of the spleen-yang, retention of water-damp in the body, fullness in chest and hypochondrium, coughs inverse dizziness and waits phlegm retention syndrome.

Balloonflower root: bitter, pungent, slightly warm in nature, enters lung channel, has effect of expelling phlegm and arresting coughing, the apocenosis of a surname's lung, cures mainly the cards such as coughing with a lot of sputum, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache, aphthae, red eye, swell pain, uroschesis.

Franzenbach rhubarb root and rhizome: latin name radix et Rhizome Rhei Franzenbachii, be the root and rhizome of polygonaceae plant rheum rhabarbarum, bitter; Cold in nature, return stomach; Large intestine channel, has removing toxic substances of purging heat; Effect of the cool blood stasis of blood, cures mainly jaundice with damp-heat pathogen; Dysentery; Through closing stomachache; Hematemesis and epistaxis; Fall and beat stasis of blood pain; Carbuncle swells serious case of furuncle; The erosion of mucous membrane in the oral cavity; The cards such as burn and scald.

Barrenwort: latin name epimedii Folium, taste is pungent, sweet, warm in nature, enters liver, kidney channel, has kidney-replenishing, strengthening the bones and muscles, effect of wines used as antirheumatic, cures mainly impotence due to deficiency of the kidney, premature ejaculation of passing out semen, waist knee impotence are soft, cold extremities with aversion to cold; The cards such as numbness and ache of cold dampness or spasm of limbs numbness.

Giant knotweed: latin name polygoni Cuspidati Rhizoma et Radix, micro-hardship, is slightly cold.Return liver, courage, lung channel, have clearing heat and detoxicating, normalizing gallbladder to cure jaundice, expelling wind and removing dampness, loose stasis of blood analgesic therapy, relieving cough and reducing sputum effect, for joint pain, jaundice with damp-heat pathogen, through Bi ， wei lump in the abdomen, coughing with a lot of sputum, scald, injury from falling down, the cards such as carbuncle sore tumefacting virus.

Cordate houttuynia: latin name houttuyniae herba, taste is pungent, cold nature, enters lung, urinary bladder channel, has clearing heat and detoxicating, removing pus and relieving carbuncle, effect of inducing diuresis for treating strangurtia, and for lung carbuncle pyemesis, phlegm heat is coughed and breathed heavily, toxic-heat and blood stasis, damp-heat gonorrhoea, hot carbuncle carbuncle, and snakeworm wants first-class card.

Yncaria stem with hooks: taste is sweet, slightly warm in nature, enters Liver Channel, has the effect of heat-clearing, calming the liver, relieving convulsion and spasm, and be mainly used in the anxious raw wind of heat or the caused spasm of liver wind agitation, twitch, restlessness, liver-yang hyperactivity or Liver Channel have the headache of heat dizzy, the symptoms such as red eye, swell pain.

Paper mulberry Fruit: taste is sweet, cold in nature, return liver, kidney channel, there is kidney tonifying clearing liver, effect of improving eyesight diuresis, cure mainly kidney deficiency and liver, soreness and weakness of waist and knees, consumptive disease hectic fever due to yin, have a dizzy spell, the card such as oedema turgor.

Selaginella tamariscina: latin name selaginellae Herba, be the dry herb of Spikemoss plant Selaginella tamariscina or Selaginella pulvinata: taste is pungent, and property is put down, and returns liver, the heart channel of Hang-Shaoyin, has effect of activating blood to promote menstruation, and for through closing dysmenorrhoea ， wei lump in the abdomen lump in the abdomen, injury from falling down, spit blood, uterine bleeding, has blood in stool, the cards such as prolapse of the anus.

Grass-leaved sweetflag: taste is pungent, warm in nature, enter the heart, stomach warp, have inducing resuscitation of having one's ideas straightened out, effect of removing dampness to restore normal functioning of the stomach, be used for the treatment of phlegm and cover clear key, coma is demented, dizziness, insomnia, forgetful, tinnitus, damp retention in middle-jiao, the cards such as abdominal distention, these product are pungent to be opened bitter dry temperature and leads to, fragrance is walked to alter, and not only has the merit of inducing resuscitation of having one's ideas straightened out, and has dampness elimination concurrently, slit phlegm, wards off dirty effect therefore be good at that to control the phlegm mind that foul heresy hoodwinks key clearly caused that wets dazed and confused, is apt to that dampness elimination is turbid, stomach of being amusing, promoting the circulation of qi is stagnant, dissipate-swelling is full.

Bush: latin name sappan lignum, taste is pungent, warm in nature, the thoughts of returning home, the spleen channel, have have one's ideas straightened out, effect of pain relieving, for apoplexy coma due to blocking of the respiratory system, suddenly faint, chest impediment and cardialgia, the cards such as chest abdomen crymodynia.

Sea-buckthorn: taste acid; Puckery; Warm in nature, have relieving cough and reducing sputum; Stomach strengthening and digestion promoting; Effect of promoting blood circulation to remove blood stasis.Cure mainly coughing with a lot of sputum; Pulmonary abscess; Indigestion; Dyspeptic abdominalgia; Stomachache; Enteritis; Amenorrhoea; Fall and beat card such as the stasis of blood swollen grade.

Horse tooth is looked for: cold in nature, and the sweet acid of taste, enters the heart, liver, spleen, large intestine channel, and have clearing heat and detoxicating, Li Shui dries, and loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effect of the cool blood that stops blooding, cures mainly dysentery, enteritis, ephritis, and postpartum, uterine hemorrhage, had blood in stool, the illnesss such as mastitis.

Lycopodium calvatum: bitter, pungent, warm in nature, enters Liver Channel, has expelling wind and clearing away cold, dehumidifying detumescence, the effect of stimulating the circulation of the blood and cause the muscles and joints to relax, for wind-cold-dampness arthralgia, and limb softening wood, pungent loose, bitter dry, the Wen Tong of this product, can Eradicates rheumatism, enters the especially kind network that stimulates the menstrual flow of liver; Control wind-cold-dampness arthralgia, joint pain, joint stuffiness.

Stringy stonecrop: taste is sweet, light, cool in nature, returns liver, courage, small intestinl channel, has eliminating dampness and heat, effect of removing toxic substances, and for jaundice with damp-heat pathogen, difficult urination, carbuncle swells the cards such as sore, acute hepatitis, chronic hepatitis.

Bilobed grewia root stem and leaf: taste is sweet, bitter, warm in nature, returns lung, the spleen channel, has invigorating the spleen, dispel rheumatism, and astringent or styptic treatment for spontaneous sweating effect cures mainly insufficiency of the spleen food few, rush down prolapse of the anus for a long time, gas ruffian, infantile malnutrition, prolonged illness is weak, infantile malnutrition, roundworm disease, arthralgia due to wind-dampness, the enuresis, seminal emission, uterine bleeding, under band, the prolapse of uterus, the cards such as testiclar gall.

Water phoenix is celestial: the herb being Balsaminaceae impatiens Chinese snapweed stem and leaf flower, bitter, pungent, and property is put down, and has clearing heat and detoxicating, promoting blood circulation to remove blood stasis, and effect of carbuncle of disappearing of drawing out the pus, cures mainly infantile pneumonia, abscess of throat, carbuncle pyogenic infections from tumour or sore, the cards such as pulmonary tuberculosis.

Pennywort: pungent, the micro-hardship of taste, cool in nature, have clearing heat and promoting diuresis, effect of removing toxicity for detumescence, cures mainly jaundice, dysentery, oedema, stranguria, and larynx swells, herpes zoster, the cards such as traumatic injury.

Maidenhair: be the herb of composite family plants of tagetes species maidenhair, bitter, property is put down, and have clearing heat and promoting diuresis, effect of cough-relieving pain relieving, cures mainly the infection of the upper respiratory tract, dysentery, cough, pertussis, toothache, acute conjunctivitis due to pathogenic wind-fire, the cards such as mastitis.

Present invention also offers a kind of duck feed, by the Chinese medicinal powder of above-mentioned control duck infectious serositis is added in duck feed, feeding duck, thus realize the control to duck infectious serositis.

The raw material of described duck feed comprises corn, wheat, corn protein powder, Fed Protein Powder of Pea Insteal, calcium monohydrogen phosphate, salt, threonine, methionine, liquid phytase, vitamin premix, mineral substance premix and above-mentioned Chinese medicinal powder.

Further preferably, described duck feed is only made up of above-mentioned raw materials.

In described duck feed, the weight of each raw material is respectively corn 2.5kg ~ 3.5kg, wheat 2kg ~ 3kg, corn protein powder 300g ~ 400g, Fed Protein Powder of Pea Insteal 100g ~ 200g, calcium monohydrogen phosphate 150g ~ 250g, salt 50g ~ 70g, threonine 20g ~ 30g, methionine 20g ~ 30g, liquid phytase 10g ~ 20g, vitamin premix 50g ~ 70g, mineral substance premix 50g ~ 70g and above-mentioned Chinese medicinal powder 600g ~ 700g.

Further preferably, in described duck feed, the weight of each raw material is respectively corn 3kg, wheat 2.5kg, corn protein powder 400g, Fed Protein Powder of Pea Insteal 200g, calcium monohydrogen phosphate 200g, salt 60g, threonine 20g, methionine 20g, liquid phytase 10g, vitamin premix 60g, mineral substance premix 60g and above-mentioned Chinese medicinal powder 700g.

Described vitamin premix be Qingdao Hemei Feed Co., Ltd. produce vitamin premix DV12, vitamin premix DV22, one or more in vitamin premix DV32.

Described microelement pre-mix material is the microelement pre-mix material M-P that Qingdao Hemei Feed Co., Ltd. produces.

Present invention also offers the preparation method of above-mentioned feed, it comprises:

The first step, prepares described Chinese medicinal powder according to the method described above;

Second step, gets all raw materials by weight, mixing, and drop into pulverizer and pulverize, grinding particle size is 20 ~ 40 orders;

3rd step, drop into granulator and granulate, pelleting temperature is 70 ~ 85 DEG C, makes its gelatinization degree reach 90%, obtains product.

Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.

Embodiment 1 Chinese medicinal powder 1

Get radix paeoniae rubrathe 220g, franzenbach rhubarb root and rhizome 140g, barrenwort 230g, giant knotweed 260g, Paper mulberry Fruit 180g, Selaginella tamariscina 130g, bush 130g, sea-buckthorn 140g, lycopodium calvatum 150g, bilobed grewia root stem and leaf 100g and maidenhair 130g, pulverizes respectively, mixing, the determining alcohol of 7kg is 95% ethanolic solution subsequently, adds hot reflux 3 hours, filters, obtain the first extract, the determining alcohol that filter residue adds 5.5kg is again 95% ethanolic solution, adds hot reflux 2 hours, filter, obtain the second extract, extract is merged, reduced pressure concentration removing ethanol, obtains dry lotion, adopts super-fine powder mill to pulverize, grinding particle size 300 order, by cassia twig 200g, balloonflower root 170g, cordate houttuynia 200g, yncaria stem with hooks 130g, grass-leaved sweetflag 100g, horse tooth looks for 130g, stringy stonecrop 130g, the celestial 100g of water phoenix, pennywort 140g pulverizes respectively, mixing, and boiling three times adds the water of 14.5kg, second for the first time, be the water of 12kg for three times, each decoction 2 hours, collecting decoction, filters, concentrated except anhydrating, obtain dry lotion, adopt super-fine powder mill to pulverize, grinding particle size 300 order, by the powder after the ultramicro grinding that obtains above, add the starch relative to powder twice quality, stir, obtain Chinese medicinal powder 1.

Embodiment 2 Chinese medicinal powder 2

Get radix paeoniae rubrathe 200g, franzenbach rhubarb root and rhizome 120g, barrenwort 200g, giant knotweed 250g, Paper mulberry Fruit 160g, Selaginella tamariscina 100g, bush 100g, sea-buckthorn 120g, lycopodium calvatum 120g, bilobed grewia root stem and leaf 80g and maidenhair 120g, pulverizes respectively, mixing, the determining alcohol of 7kg is 95% ethanolic solution subsequently, adds hot reflux 3 hours, filters, obtain the first extract, the determining alcohol that filter residue adds 5.5kg is again 95% ethanolic solution, adds hot reflux 2 hours, filter, obtain the second extract, extract is merged, reduced pressure concentration removing ethanol, obtains dry lotion, adopts super-fine powder mill to pulverize, grinding particle size 300 order, by cassia twig 180g, balloonflower root 150g, cordate houttuynia 170g, yncaria stem with hooks 120g, grass-leaved sweetflag 80g, horse tooth looks for 100g, stringy stonecrop 110g, the celestial 80g of water phoenix, pennywort 120g pulverizes respectively, mixing, and boiling three times adds the water of 14kg, second for the first time, be the water of 12kg for three times, each decoction 2 hours, collecting decoction, filters, concentrated except anhydrating, obtain dry lotion, adopt super-fine powder mill to pulverize, grinding particle size 300 order, by the powder after the ultramicro grinding that obtains above, add the starch relative to powder twice quality, stir, obtain Chinese medicinal powder 2.

Embodiment 3 Chinese medicinal powder 3

Get radix paeoniae rubrathe 250g, franzenbach rhubarb root and rhizome 160g, barrenwort 250g, giant knotweed 280g, Paper mulberry Fruit 200g, Selaginella tamariscina 150g, bush 150g, sea-buckthorn 160g, lycopodium calvatum 170g, bilobed grewia root stem and leaf 120g and maidenhair 150g, pulverizes respectively, mixing, the determining alcohol of 7kg is 95% ethanolic solution subsequently, adds hot reflux 3 hours, filters, obtain the first extract, the determining alcohol that filter residue adds 5.5kg is again 95% ethanolic solution, adds hot reflux 2 hours, filter, obtain the second extract, extract is merged, reduced pressure concentration removing ethanol, obtains dry lotion, adopts super-fine powder mill to pulverize, grinding particle size 300 order, by cassia twig 220g, balloonflower root 190g, cordate houttuynia 220g, yncaria stem with hooks 150g, grass-leaved sweetflag 120g, horse tooth looks for 150g, stringy stonecrop 150g, the celestial 120g of water phoenix, pennywort 160g pulverizes respectively, mixing, and boiling three times adds the water of 14.5kg, second for the first time, be the water of 12kg for three times, each decoction 2 hours, collecting decoction, filters, concentrated except anhydrating, obtain dry lotion, adopt super-fine powder mill to pulverize, grinding particle size 300 order, by the powder after the ultramicro grinding that obtains above, add the starch relative to powder twice quality, stir, obtain Chinese medicinal powder 3.

Acute toxicity testing

Require to carry out prerun according to acute toxicity test, find that test medicine cannot measure LD ₅₀.Therefore carry out maximum dosage-feeding test in a day.Get above-mentioned mouse 40, fasting can't help water after 12 hours, administration group and water control group is divided at random by body weight, often organize 20, administration group gives the liquid 0.4ml/10g of the crude drug amount 2.4g/ml concentration of the Chinese medicinal powder 1 prepared containing embodiment 1, gavage one day 2 times, make dosage in a day reach symphysis dose 192.0g/kg, water control group is to the water of equal volume.After each treated animal administration, 5, every box, normal raising, close observation, equal Continuous Observation seven days, the toxic reaction that record may occur and death condition, after administration, mouse outward appearance hair color light, behavioral activity is normal, pathologic neural reflex without exception occurs, in seven days, feed is good, and other Novel presentation is seen at end, changes of weight no significant difference and none animal dead compared with water control group, visually observe the main organs such as the heart, liver, spleen, lung, kidney, without general pathology changes such as significantly hemorrhage, tissue degeneratiaon, necrosis.

Long term toxicity test

Experiment establishes 2 groups altogether: Chinese medicinal powder group of the present invention (dosage is respectively 51.6g crude drug in whole/kg) and blank group, big white mouse in 9 week age is gavaged for continuous 180 days, administration 90 days, 180 days and drug withdrawal are after 30 days, put to death rat respectively, check each treated animal hematological indices [red blood cell (RBC), mean corpuscular volume (MCV) (MCV), hematid specific volume (HCT), blood platelet (PLT), mean platelet volume (MPV), leucocyte (WBC), hemoglobin (HGB), mean corpusular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) (MCHC), lymphocyte percentage (LPR), neutrophil percentage (GPR), intermediate value cell percentage (MPR), RDW (RDWR), RDW number (RDWA), Reticulocyte percentage (RET), agglutinate blood zymogen time (PT)], blood biochemical analysis index [glutamic-pyruvic transaminase (ALT), total protein (TP), albumin (ALB), total bilirubin (TBIL), glutamic-oxalacetic transaminease (AST), creatine kinase (CK), creatinine (CREA), urea nitrogen (BUN), blood sugar (GLU), T-CHOL (CHOL), triglyceride (TG), glutamine aminopherase (GGT), alkaline phosphatase (ALP), serum potassium ion (K ⁺), serum sodium ion (Na ⁺), serum chloride ion (Cl ^-)].All animal hearts, liver, spleen, lung, kidney, brain, uterus, ovary, thymus gland, adrenal gland are visually observed, and calculating organ index of weighing, simultaneously to blank group and the Traditional Chinese medicine immune preparation treated animal heart, liver, spleen, lung, kidney, brain (brain, cerebellum, brain stem), hypophysis, optic nerve, sciatic nerve, spinal cord (cervical part of esophagus, chest section, waist section), uterus, ovary, mammary gland, thyroid gland, thymus gland, pancreas, adrenal gland, salivary gland (salivary gland), esophagus, stomach, duodenum, return, colon, bladder, lymph node (submandibular lymph nodes, lymphonodi mesenterici), tracheae, sustainer carries out Pathomorphology inspection.

Result shows: each administration treated animal is in the different dosing cycle, and above index compares with control group, discovery all without exception, and hematology and biochemical index are all in range of normal value.

It is safe that result shows that Chinese medicinal powder long-term, high-dose of the present invention uses.

Embodiment 4 feed 1

The microelement pre-mix material M-P60g that vitamin premix DV12 corn 3kg, wheat 2.5kg, corn protein powder 400g, Fed Protein Powder of Pea Insteal 200g, calcium monohydrogen phosphate 200g, salt 60g, threonine 20g, methionine 20g, liquid phytase 10g, 60g Qingdao Hemei Feed Co., Ltd. produced, Qingdao Hemei Feed Co., Ltd. produce and Chinese medicinal powder 700g prepared by embodiment 1 mixes; drop into pulverizer to pulverize; grinding particle size is 40 orders; drop into granulator to granulate; pelleting temperature is 85 DEG C; make its gelatinization degree reach 90%, obtain product.

Comparative example 1 feed 2

The microelement pre-mix material M-P60g that vitamin premix DV12 corn 3kg, wheat 2.5kg, corn protein powder 400g, Fed Protein Powder of Pea Insteal 200g, calcium monohydrogen phosphate 200g, salt 60g, threonine 20g, methionine 20g, liquid phytase 10g, 60g Qingdao Hemei Feed Co., Ltd. produced, Qingdao Hemei Feed Co., Ltd. produce mixes; drop into pulverizer to pulverize; grinding particle size is 40 orders; drop into granulator to granulate; pelleting temperature is 85 DEG C; make its gelatinization degree reach 90%, obtain product.

Experiment proves

Material

Bacterial classification: test riemerella anatipestifer is given by Shandong Agricultural University's veterinary college.

Medicine: Chinese medicinal powder 1 prepared by the embodiment of the present invention 1.

The separation of cause of disease: asepticly take die of illness duck blood, liver, blood agar plate is rule, and candle jar method cultivates 24 h, observes bacterial growth characteristic.By colonies typical, streak inoculation is dull and stereotyped in blood agar plate, tryptic soy agar flat board (TSA), maconkey agar flat board and plain agar respectively, every strain bacterium inoculates two flat boards, a dull and stereotyped candle jar method is cultivated, and another is directly put into 37 DEG C of insulating boxs and cultivates.Observe colonial morphology and microscopy after 48 h, the suspicious bacterium colony of picking preserves qualification after purifying on tryptic soy agar flat board.

Bacterial culture and count: the riemerella anatipestifer through qualification is inoculated in TSA flat board, 1 ~ 2 colony inoculation is got in tryptic soy broth medium after cultivation, be placed on 200r/min, 24 h are cultivated in (36.9 ± 0.1) DEG C constant-temperature table, then bacterium liquid sample is got, survey its OD600 value, be adjusted to about 0.15, 10 times of serial dilutions are carried out again with sterile saline, getting 100 μ L dilution bacterium liquid is added on TSA flat board, even with the coating of aseptic glass rake, and horizontal rest 10 min, each dilution factor does 3 repetitions, observe counting cultivate 18 ~ 24h in 37 DEG C of candle cylinders after and (control bacterial population 10 ⁸individual/mL).

Odontothrips loti drug sensitivity test: drawing with liquid-transfering gun the concentration prepared is 10 ⁸cfu/mL(OD600=0.15) bacteria suspension 500 μ L, on tryptic soy agar flat board, even with the coating of aseptic glass rake, horizontal rest 10 min, then clamps aseptic Oxford cup with aseptic nipper, is placed on gently equably on flat board.Be dissolved in water by Chinese medicinal powder prepared by embodiment 1, obtaining crude drug concentration is the solution of 1g/ml, and draw in above-mentioned Chinese medicinal powder 1 to the Oxford cup prepared of 100 μ L, candle jar method cultivates 24 h, measures and records inhibition zone size (mm).It is resistance that antibacterial circle diameter is less than 10 mm; 10 ~ 15 mm are less sensitive; 16 ~ 20 mm are medium sensitivity; 20 more than mm are extremely sensitive.

Result of the test:

Drug sensitivity test result

The Chinese medicinal powder 1 pair of riemerella anatipestifer adopting the embodiment of the present invention 1 to prepare is antibacterial circle diameter is 50.0mm, is high sensitive.

Embodiment 9 Animal experiment

Animal data: Wu buys 2100 ducklings on September 2nd, 2013, puts into the other stable breeding in pool.Raise to finding during July 25 to occur on a small quantity in duck group that leg is soft, necking down, lethargic sleep, draw the symptoms such as yellow green loose stool.When going to a doctor to the author dead more than 20 successively, once used the drug therapy such as Ciprofloxacin, orfloxacin, poor effect.

Clinical symptoms and case change

Sick duck show as spirit depressed, squat, necking down, neck be crooked, instability of gait and incoordination, search for food and reduce or do not eat, sick duck eye and nares have serosity or mucus secretion, green or the yellow green loose stool of row is along with the development of the course of disease, the person's showed increased that occurs nervous symptoms in duck group, show as neck crooked, nod, two limbs stretch in nervous symptoms such as opisthotonos.

Cut open inspection change

Cut open inspection to die of illness duck 5, the most significantly cuing open inspection pathology is the scorching and meningitis of fibrinous pericarditis, perihepatitis, air bag.The more anxious visible epicardial surface of case of the course of disease has fibrinous exudate, and then pericardium thickens the slower person of the course of disease, surface and cavum pericardiale have a large amount of cheesy exudates, pericardiosymphysis.Liver enlargement, performance has fibrinous exudate, and severe patient forms the thick cellulose membrane of one deck and is covered in whole liver surface.Spleen enlargement, surface is in marbleized appearance.

Laboratory examination

Smear for microscopic examination: sterile working is taked to die of illness the liver of duck, spleen, heart tissue's direct smear, and the visible Gram-negative of gram stain microscopy, the dense dye in the two poles of the earth, in the bacillus pumilis of single existence.

Bacteria Culture

Disease duck liver, spleen are got in sterile working, be inoculated in blood agar inclined-plane and maconkey agar flat board respectively, observe cultivate 48 h under 37 DEG C of environment in candle cylinder after, visible diameter 1.5 ~ 2 mm on blood agar inclined-plane, present circle, projection, butyrous bacterium colony, not haemolysis, the single colony IFA technique microscopy of picking, viewed ne ar is identical with seen by pathological material of disease smear for microscopic examination.Maconkey agar flat board has no bacterial growth.According to incidence, clinical symptoms, cut open inspection change, Binding experiment room checks, is diagnosed as duck infectious serositis.

Methods for the treatment of

From the duck of survival, choose 1800 be divided into 3 groups, first group adopts the former treated powder of Enrofloxacin, add in drinking water according to 10g/100kg, for the free diet of duck, second group of feed 1 adopting the embodiment of the present invention 4 to prepare, for duck free choice feeding, the 3rd group of feed 2 only adopting conventional feeds method feeding comparative example 1 to prepare, do not add any medicine, each group is raised 5 days continuously, observed result.

Criterion

In medication 5 days, cardinal symptom disappears or is obviously improved as effectively, is invalidly not improved for sings and symptoms.

The results are shown in Table 1.

Table 1 medicine is to the result for the treatment of of duck infectious serositis

Group	Treatment number (only)	Significant figure (only)	Efficient (%)	Death toll (only)	The death rate (%)
						First group	600	502	83.7	98	16.3
Second group	600	579	96.5	21	3.5
						3rd group	600	57	9.5	543	90.5

As can be seen from Table 1, Chinese medicinal powder of the present invention is adopted to have significant curative effect to duck infectious serositis.

All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.

The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (9)

1. prevent and treat a feed for duck infectious serositis, it is characterized in that: raw material comprises corn, wheat, corn protein powder, Fed Protein Powder of Pea Insteal, calcium monohydrogen phosphate, salt, threonine, methionine, liquid phytase, vitamin premix, mineral substance premix and the Chinese medicinal powder for preventing and treating duck infectious serositis.

2. feed as claimed in claim 1, its spy is well: the weight of each raw material is respectively corn 2.5kg ~ 3.5kg, wheat 2kg ~ 3kg, corn protein powder 300g ~ 400g, Fed Protein Powder of Pea Insteal 100g ~ 200g, calcium monohydrogen phosphate 150g ~ 250g, salt 50g ~ 70g, threonine 20g ~ 30g, methionine 20g ~ 30g, liquid phytase 10g ~ 20g, vitamin premix 50g ~ 70g, mineral substance premix 50g ~ 70g and described Chinese medicinal powder 600g ~ 700g.

3. feed as claimed in claim 1 or 2, its spy is well: the weight of each raw material is respectively corn 3kg, wheat 2.5kg, corn protein powder 400g, Fed Protein Powder of Pea Insteal 200g, calcium monohydrogen phosphate 200g, salt 60g, threonine 20g, methionine 20g, liquid phytase 10g, vitamin premix 60g, mineral substance premix 60g and described Chinese medicinal powder 700g.

4. the feed as described in claims 1 to 3, its spy is well: the bulk drug of described Chinese medicinal powder comprises the radix paeoniae rubrathe, cassia twig, balloonflower root, franzenbach rhubarb root and rhizome, barrenwort, giant knotweed, cordate houttuynia, yncaria stem with hooks, Paper mulberry Fruit, Selaginella tamariscina, grass-leaved sweetflag, bush, sea-buckthorn, horse tooth are looked for, lycopodium calvatum, stringy stonecrop, bilobed grewia root stem and leaf, Shui Fengxian, pennywort and maidenhair.

5. the feed as described in Claims 1-4, its spy is well: in described Chinese medicinal powder, the weight of each bulk drug is respectively radix paeoniae rubrathe 200g ~ 250g, cassia twig 180g ~ 220g, balloonflower root 150g ~ 190g, franzenbach rhubarb root and rhizome 120g ~ 160g, barrenwort 200g ~ 250g, giant knotweed 250g ~ 280g, cordate houttuynia 170g ~ 220g, yncaria stem with hooks 120g ~ 150g, Paper mulberry Fruit 160g ~ 200g, Selaginella tamariscina 100g ~ 150g, grass-leaved sweetflag 80g ~ 120g, bush 100g ~ 150g, sea-buckthorn 120g ~ 160g, horse tooth looks for 100g ~ 150g, lycopodium calvatum 120g ~ 170g, stringy stonecrop 110g ~ 150g, bilobed grewia root stem and leaf 80g ~ 120g, celestial 80g ~ the 120g of water phoenix, pennywort 120g ~ 160g and maidenhair 120g ~ 150g.

6. the feed as described in claim 1 to 5, its spy is well: in described Chinese medicinal powder, the weight of each bulk drug is respectively radix paeoniae rubrathe 210g ~ 230g, cassia twig 190g ~ 210g, balloonflower root 160g ~ 180g, franzenbach rhubarb root and rhizome 130g ~ 150g, barrenwort 220g ~ 240g, giant knotweed 260g ~ 270g, cordate houttuynia 190g ~ 200g, yncaria stem with hooks 130g ~ 140g, Paper mulberry Fruit 170g ~ 190g, Selaginella tamariscina 120g ~ 140g, grass-leaved sweetflag 90g ~ 110g, bush 120g ~ 140g, sea-buckthorn 130g ~ 150g, horse tooth looks for 120g ~ 140g, lycopodium calvatum 140g ~ 160g, stringy stonecrop 130g ~ 140g, bilobed grewia root stem and leaf 90g ~ 110g, celestial 90g ~ the 110g of water phoenix, pennywort 130g ~ 150g and maidenhair 130g ~ 140g.

7. the feed as described in claim 1 to 6, its spy is well: the preparation method of described Chinese medicinal powder is as follows:

The first step, get the radix paeoniae rubrathe, franzenbach rhubarb root and rhizome, barrenwort, giant knotweed, Paper mulberry Fruit, Selaginella tamariscina, bush, sea-buckthorn, lycopodium calvatum, bilobed grewia root stem and leaf and maidenhair, pulverize respectively, mix by above-mentioned weight, adding relative to the determining alcohol of mixture quality 3 ~ 5 times is subsequently 90% ~ 95% ethanolic solution, add hot reflux 2 ~ 4 hours, filter, obtain the first extract, it is 90% ~ 95% ethanolic solution that filter residue adds relative to the determining alcohol of its quality 2 ~ 5 times again, add hot reflux 1 ~ 2 hour, filter, obtain the second extract, extract is merged, reduced pressure concentration removing ethanol, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order,

Second step, pulverizes respectively by remaining components, mixes by above-mentioned weight, boiling three times, first time adds the water relative to mixture quality 10 ~ 12 times, and second and third time is the water of 8 ~ 10 times amount, each decoction 2 hours, collecting decoction, filter, concentrated except anhydrating, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order;

3rd step, the powder mixing after the ultramicro grinding obtain the first step and second step, adds the starch relative to mixed-powder twice quality, stirs, obtain Chinese medicinal powder.

8. the preparation method of feed described in claim 1 to 7, is characterized in that, comprising:

The first step, prepares described Chinese medicinal powder;

Second step, gets all raw materials by weight, mixing, and drop into pulverizer and pulverize, grinding particle size is 20 ~ 40 orders;

3rd step, drop into granulator and granulate, pelleting temperature is 70 ~ 85 DEG C, makes its gelatinization degree reach 90%, obtains product.

9. the preparation method of feed described in claim 1 to 8, is characterized in that: the described first step is specially further:

A walks, get the radix paeoniae rubrathe, franzenbach rhubarb root and rhizome, barrenwort, giant knotweed, Paper mulberry Fruit, Selaginella tamariscina, bush, sea-buckthorn, lycopodium calvatum, bilobed grewia root stem and leaf and maidenhair, pulverize respectively, mix by above-mentioned weight, adding relative to the determining alcohol of mixture quality 3 ~ 5 times is subsequently 90% ~ 95% ethanolic solution, add hot reflux 2 ~ 4 hours, filter, obtain the first extract, it is 90% ~ 95% ethanolic solution that filter residue adds relative to the determining alcohol of its quality 2 ~ 5 times again, add hot reflux 1 ~ 2 hour, filter, obtain the second extract, extract is merged, reduced pressure concentration removing ethanol, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order,

B walks, and is pulverized respectively by remaining components, mixes by above-mentioned weight, boiling three times, first time adds the water relative to mixture quality 10 ~ 12 times, and second and third time is the water of 8 ~ 10 times amount, each decoction 2 hours, collecting decoction, filter, concentrated except anhydrating, obtain dry lotion, employing super-fine powder mill is pulverized, grinding particle size 200 order ~ 300 order;

C walks, and the powder mixing after the ultramicro grinding obtain a step and b step, adds the starch relative to mixed-powder twice quality, stir, obtain Chinese medicinal powder.