CN103859156B - Feed for controlling duck pulp conjunctivitis, Chinese medicine composition and preparation method - Google Patents
Feed for controlling duck pulp conjunctivitis, Chinese medicine composition and preparation method Download PDFInfo
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Abstract
The invention discloses a feed for controlling duck pulp conjunctivitis, a Chinese medicine composition and a preparation method. The feed comprises a feed carrier, a feed binding agent and Chinese medicine additives, wherein the Chinese medicine additives comprise burdock, fructus forsythia, platycodon grandiflorum, schizonepeta, radix scrophulariae, scutellaria baicalensis, coptis chinensis, isatis root, folium mori, almond, straight ladybell root, radix ophiopogonis, selfheal, chrysanthemum, chastetree fruit, tribulusterrestris, astragalus membranaceus, kudzu vine root, common scouring rush herb, Chinese trichosanthis root, pipewort, butterflybush flower, semen cuscutae, cistanche, paris polyphylla and radix tinosporae. The feed has the beneficial effects that compared with a conventional feed, the feed containing the Chinese medicine additives is used for feeding ducks suffering from duck pulp conjunctivitis, the Chinese medicine additives and the feed carrier are mutually matched, thus the feed has the functions of clearing away heat and toxic materials, dispelling wind and relieving exterior syndrome, strengthening body resistance and eliminating evil, and also has the advantages of being high in cure rate, difficult in relapse, purely natural without toxic and side effects, remarkable in treatment effect, free from medicine resistance and medicine residue, capable of enhancing the disease resistance of the ducks suffering from the duck pulp conjunctivitis, low in cost and price, convenient and simple in making process, and the like.
Description
Technical field
The present invention relates to technical field of animal, particularly a kind of feed, Chinese medicine composition and preparation method for preventing and treating duck oromeningitis.
Background technology
Duck oromeningitis has another name called Pasteurella anatipestipestifer disease, new duck disease or duck septicaemia, is the chronic or acute septic infectious disease of the one of the infringement duckling caused by Pasteurella anatipestipestifer.It is characterized in that causing duckling cellulose pericarditis, perihepatitis, air bag inflammation and arthritis.The morbidity infection rate of duck infectious serositis can up to more than 90%, and the death rate is not 5% ~ 75% etc.Easily there is cross-infection in germ, makes disease long-term existence in duck field, and the raising having a strong impact on a duck production performance even jeopardizes its life.This disease is distributed in all over the world widely, causes death, to lose weight and superseded provisions duck industry causes huge economic loss.
Prevent and treat in this sick process find at employing Western medicine in recent years, western medical treatment application antibiotic, the medicine such as antiviral, drug residue is large, easy generation drug resistance, the state of an illness easily repeatedly, even can cause delay treatment, have certain adverse effect after consumer eats this type of duck for body health.
At present, there is the Chinese medicine of some treatment duck oromeningitis, compared with the Western medicine such as above-mentioned antibiotic, although have cheap advantage, but its result for the treatment of and effective speed are slowly, after taking medicine, longer a period of time just can make transference cure, so still thoroughly can not eliminate the problem of medicament residue.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of feed comprising Chinese medicine composition for preventing and treating duck oromeningitis, adopt the feed containing this Chinese medicine composition can overcome the defect of prior art Chinese and Western medicine and Chinese medicine, to suffering from the treatment of duck of duck oromeningitis from entirety, carry out diagnosis and treatment, have clearing heat and detoxicating, expelling wind to resolve the exterior, the function of strengthening vital QI to eliminate pathogenic factors, cure rate is high, not easily recur, pure natural, have no side effect, evident in efficacy, do not produce drug resistance, drug residue free, the disease resistance of ill duck can be strengthened simultaneously, cost price is cheap, the advantages such as manufacture craft is easy.
In order to realize foregoing invention object, the invention provides a kind of feed for preventing and treating duck oromeningitis, comprise feed vector, feed adhesive and Chinese medicine additive, described Chinese medicine additive comprises great burdock achene, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix scrophulariae, the root of large-flowered skullcap, the coptis, Radix Isatidis, mulberry leaf, almond, the root of straight ladybell, the tuber of dwarf lilyturf, selfheal, chrysanthemum, fructus viticis, tribulus terrestris, the Radix Astragali, the root of kudzu vine, scouring rush, root of Chinese trichosanthes, pipewort, butterflybush flower, the seed of Chinese dodder, saline cistanche, Paris polyphylla and tinosporae.
In described Chinese medicine additive, the ratio of weight and number of each bulk drug is: great burdock achene 18-37 part, capsule of weeping forsythia 9-20 part, balloonflower root 16-30 part, schizonepeta 20-35 part, radix scrophulariae 15-25 part, root of large-flowered skullcap 25-38 part, coptis 10-23 part, Radix Isatidis 17-30 part, mulberry leaf 23-36 part, almond 15-35 part, the root of straight ladybell 8-18 part, the tuber of dwarf lilyturf 12-24 part, selfheal 12-26 part, chrysanthemum 26-40 part, fructus viticis 28-40 part, tribulus terrestris 25-37 part, Radix Astragali 13-27 part, root of kudzu vine 23-35 part, scouring rush 16-33 part, root of Chinese trichosanthes 26-35 part, pipewort 22-35 part, butterflybush flower 15-30 part, seed of Chinese dodder 7-20 part, saline cistanche 13-28 part, Paris polyphylla 20-35 part and tinosporae 25-38 part.
Described feed vector comprises corn, dregs of beans and wheat.
Described feed adhesive comprises Strong flour and starch; In described feed adhesive, the ratio of weight and number of each composition is: Strong flour is 20-25 part, and starch is 25-30 part.
The ratio of weight and number of described feed vector, feed adhesive and Chinese medicine additive is 100 weight portions: 20-45 weight portion: 4-8 weight portion.
Described starch comprises uncooked amylum and ripe starch; The ratio of weight and number of described uncooked amylum and described ripe starch is 40-50 part: 15-25 part; Described Strong flour is the flour that protein wt degree is greater than 20%.
In described Chinese medicine additive, the ratio of weight and number of each bulk drug is: great burdock achene 20-32 part, capsule of weeping forsythia 11-18 part, balloonflower root 18-26 part, schizonepeta 22-33 part, radix scrophulariae 18-22 part, root of large-flowered skullcap 27-35 part, coptis 13-23 part, Radix Isatidis 20-30 part, mulberry leaf 23-30 part, almond 15-30 part, the root of straight ladybell 8-14 part, the tuber of dwarf lilyturf 14-20 part, selfheal 14-22 part, chrysanthemum 26-36 part, fructus viticis 28-35 part, tribulus terrestris 27-33 part, Radix Astragali 15-25 part, root of kudzu vine 25-35 part, scouring rush 20-33 part, root of Chinese trichosanthes 28-32 part, pipewort 22-30 part, butterflybush flower 17-25 part, seed of Chinese dodder 10-18 part, saline cistanche 15-25 part, Paris polyphylla 22-32 part and tinosporae 27-35 part.
In described feed vector, the ratio of weight and number of each component is: corn 30-45 part, dregs of beans 20-45 part, wheat 30-50 part.
Present invention also offers a kind of preparation method of the feed for preventing and treating duck oromeningitis, it is characterized in that, described preparation method comprises:
(1) take all bulk drug mixed grindings according to percentage by weight and become 140-200 order fine powder, be prepared into Chinese medicine additive;
(2) get feed adhesive in proportion, then add and be the water of 30-35% relative to feed adhesive weight ratio and stir, whipping temp is 75-82 DEG C, and the mixture after stirring is poured in spraying machine;
(3) get described feed vector in proportion to pulverize, grinding particle size is 300-460mm, and its fine powder amount is reached, and feed vector always expects more than 97%;
(4) feed vector after described step (3) being pulverized is poured in spraying machine, and the feed adhesive after stirring with step (2) mixes, and in spray, water temperature is 70-86 DEG C, opens spraying machine, stirs 10-12 minute, continues to be warming up to 95 DEG C and complete expanded;
(5) the expanded product that obtains of pulverising step (4), then the Chinese medicine additive adding that step (1) obtains, obtain mixture, add the water of parts by weight 8-15 part of the mixture relative to 100 weight portions, put into granulator and granulate;
(6) dry after granulating, baking temperature is 102 DEG C ~ 115 DEG C, drying time 25-40min; Then cool, pack.
Present invention also offers a kind of Chinese medicine composition for preventing and treating duck oromeningitis, in described Chinese medicine composition, the ratio of weight and number of each bulk drug is: great burdock achene 18-37 part, capsule of weeping forsythia 9-20 part, balloonflower root 16-30 part, schizonepeta 20-35 part, radix scrophulariae 15-25 part, root of large-flowered skullcap 25-38 part, coptis 10-23 part, Radix Isatidis 17-30 part, mulberry leaf 23-36 part, almond 15-35 part, the root of straight ladybell 8-18 part, the tuber of dwarf lilyturf 12-24 part, selfheal 12-26 part, chrysanthemum 26-40 part, fructus viticis 28-40 part, tribulus terrestris 25-37 part, Radix Astragali 13-27 part, root of kudzu vine 23-35 part, scouring rush 16-33 part, root of Chinese trichosanthes 26-35 part, pipewort 22-35 part, butterflybush flower 15-30 part, seed of Chinese dodder 7-20 part, saline cistanche 13-28 part, Paris polyphylla 20-35 part and tinosporae 25-38 part.
The preparation method of described Chinese traditional medicine composition composition powders comprises
Step one, all bulk drugs are dropped in proportion in mixer stir, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6-1Mpa process, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition added again relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6Mpa-1Mpa process, filter and obtain the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
The beneficial effect that technical scheme provided by the invention is brought is: relative to the medicine for preventing and treating duck oromeningitis of the prior art, the Feed Energy containing this Chinese medicine composition is adopted to overcome the various defects of Chinese medicine of the prior art and Western medicine, to suffering from the treatment of duck of duck oromeningitis from entirety, carry out diagnosis and treatment, have clearing heat and detoxicating, expelling wind to resolve the exterior, the function of strengthening vital QI to eliminate pathogenic factors, cure rate is high, not easily recur, pure natural, have no side effect, evident in efficacy, do not produce drug resistance, drug residue free, the disease resistance of ill duck can be strengthened simultaneously, cost price is cheap, the advantages such as manufacture craft is easy.
Detailed description of the invention
The invention provides a kind of feed for preventing and treating duck oromeningitis, comprise feed vector, feed adhesive and Chinese medicine additive, described Chinese medicine additive comprises great burdock achene, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix scrophulariae, the root of large-flowered skullcap, the coptis, Radix Isatidis, mulberry leaf, almond, the root of straight ladybell, the tuber of dwarf lilyturf, selfheal, chrysanthemum, fructus viticis, tribulus terrestris, the Radix Astragali, the root of kudzu vine, scouring rush, root of Chinese trichosanthes, pipewort, butterflybush flower, the seed of Chinese dodder, saline cistanche, Paris polyphylla and tinosporae.
In Chinese medicine additive, the ratio of weight and number of each bulk drug is: great burdock achene 18-37 part, capsule of weeping forsythia 9-20 part, balloonflower root 16-30 part, schizonepeta 20-35 part, radix scrophulariae 15-25 part, root of large-flowered skullcap 25-38 part, coptis 10-23 part, Radix Isatidis 17-30 part, mulberry leaf 23-36 part, almond 15-35 part, the root of straight ladybell 8-18 part, the tuber of dwarf lilyturf 12-24 part, selfheal 12-26 part, chrysanthemum 26-40 part, fructus viticis 28-40 part, tribulus terrestris 25-37 part, Radix Astragali 13-27 part, root of kudzu vine 23-35 part, scouring rush 16-33 part, root of Chinese trichosanthes 26-35 part, pipewort 22-35 part, butterflybush flower 15-30 part, seed of Chinese dodder 7-20 part, saline cistanche 13-28 part, Paris polyphylla 20-35 part and tinosporae 25-38 part.
Wherein, in Chinese medicine additive, the pungent loose hardship of great burdock achene let out can dispelling wind and heat from the body, a surname's lung eliminate the phlegm, detoxify, relieve sore throat, the compatibility capsule of weeping forsythia, balloonflower root, schizonepeta, radix scrophulariae, the root of large-flowered skullcap, the coptis, Radix Isatidis are with using; Mulberry leaf energy dispelling wind and heat from the body, clearing away the lungheat and moisturizing, suppressing liver-YANG, clear liver and improve vision, compatibility almond, the root of straight ladybell, the tuber of dwarf lilyturf, selfheal, chrysanthemum are with using; Fructus viticis can dispelling wind and heat from the body, the clear sharp head, with tribulus terrestris, the Radix Astragali, root of kudzu vine compatibility with using; Scouring rush can dispelling wind and heat from the body, removing nebula, returns lung, Liver Channel, with pipewort, butterflybush flower, selfheal, chrysanthemum, compatibility with using; Root of Chinese trichosanthes sweet cold, can clearing heat-fire, can promote the production of body fluid to quench thirst again, with the root of straight ladybell, the tuber of dwarf lilyturf compatibility with using; Butterflybush flower can clearing liver, again can nourishing the liver, with the seed of Chinese dodder, saline cistanche compatibility with using; Paris polyphylla can clearing heat and detoxicating, swelling and pain relieving, the arresting convulsion of cool liver, with great burdock achene, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix scrophulariae, the root of large-flowered skullcap, the coptis, Radix Isatidis compatibility with using; Tinosporae can clearing heat and detoxicating, relieve sore throat, pain relieving.
The pharmacology of described each bulk drug is as follows:
Great burdock achene: taste is pungent is bitter, cold in nature.Return lung, stomach warp.Can dispelling wind and heat from the body; Clearing heat and detoxicating promoting eruption; A surname's lung relieve sore throat is loose swollen.Cure mainly anemopyretic cold, warm disease from the beginning of; Wind-heat or cough with lung heat, cough up phlegm not smooth; Abscess of throat; Macula is not saturating; At the measles initial stage, rash goes out not smooth and rubella itch; Sore swollen toxin and mumps etc.
The capsule of weeping forsythia: bitter, cold nature.The thoughts of returning home, lung, small intestinl channel.The pharmacological action such as have antibacterial, cardiac stimulant, diuresis, town to tell is clearing heat and detoxicating Chinese medicine, cure mainly pyreticosis from the beginning of, anemopyretic cold, heating, vexed, the symptom such as abscess of throat, acute nephritis, carbuncle sore tumefacting virus.
Balloonflower root: bitter, pungent, property is put down.Return lung channel.There is a surname's lung, eliminate the phlegm, relieve sore throat, apocenosis, sharp the five internal organs, effect of filling blood, mending the exhaustion or lesion of the five internal organs, foster the spirit of nobility.Cure mainly coughing with a lot of sputum, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache, aphthae, red eye, swell pain, uroschesis.
Schizonepeta: taste is pungent, micro-hardship, property is micro-wet.Return lung, Liver Channel.Main cold, fever, headache, eye itching, cough, abscess of throat, measles, carbuncle swells, sore scabies, postpartum anemic fainting.For flu, headache, measles, rubella, sore from the beginning of.
Radix scrophulariae: taste is sweet, bitter, salty, cold nature.Return lung, stomach, kidney channel.There is clearing heat and cooling blood, purging intense heat and detonicating, effect of enriching yin, cure mainly warm heat disease heat and ying blood, body heat, polydipsia, tongue are deep red, a spot, hectic fever due to yin labor are coughed, the cards such as constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula subcutaneous nodule, skin sore are not hindered in awake, Tianjin to dysphoria.Taste have wet and insufficiency of the spleen loose stool person to avoid clothes.
The root of large-flowered skullcap: property is bitter, cold.Return lung, courage, spleen, large intestine, small intestinl channel.Can heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, antiabortive, hypotensive.For damp-warm syndrome, heat temperature evil of vomitting uncomfortable in chest, damp and hot ruffian is full, and rush down dysentery, jaundice, cough with lung heat, high hot polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, fetal irritability.
The coptis: bitter, cold, nontoxic.The thoughts of returning home, spleen, stomach, liver, courage, large intestine channel.Function heat-clearing and damp-drying drug, purging intense heat and detonicating.Full for damp and hot ruffian, vomiting acid regurgitation, rushes down dysentery, jaundice, unconsciousness due to high fever, is longer than the fire of removing the heart-fire stomach, and have preventing or arresting vomiting concurrently and to disappear the merit of ruffian, can be used for the prosperous caused dysphoria and insomnia for the treatment of internal heat, blood-head tells nosebleed, hot eyes, has a toothache, quenches one's thirst, and carbuncle swells furunculosis; Control eczema outward, wet sore, duct is suppurated.It is burning hot that prepared RHIZOMA COPTIDIS with vino is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.
Radix Isatidis: nature and flavor, bitter cold.Heat-clearing, removing toxic substances, cool blood, relieve sore throat.Cure mainly febrile virulent maculae, high heat headache, major part pestilence, tongue is secretly dark reddish purple, scarlet fever, erysipelas, mumps, larynx numbness, and sore is swollen, carbuncle swells, varicella, measles, hepatitis, influenza, epidemic meningitis, encephalitis, pneumonia, and coma tells nosebleed, and pharynx is swollen, pinkeye, sore rash.
Mulberry leaf: bitter, sweet, cold in nature.Return lung, Liver Channel.Profit the five internal organs, get round by bribery, lower gas, decoction; Except wind pain is perspired, and flutter damage hemostasis, and Zheng Hou An; Centipede stings snakeworm, and salt Norway applies.
Almond: bitter, tepor; Slightly poisonous." Mingyi Bielu ": main cough with dyspnea is thundered, larynx numbness, lower gas, galactopoiesis metal-inflicted wound, the bitterly disappointed globefish that runs quickly.Control abdomen numbness obstructed, sweating, main warm disease.Control epigastric oppression completely pain, except trusted subordinate is unhappy, treat lung qi cough, the shortness of breath.Enter lucid asparagus to decoct, profit cardiopulmonary.Soup can be made, benefit profit information with junket.Place i.e. dynamic cold air.
The root of straight ladybell: cold nature, sweet, the micro-hardship of taste.There is nourishiing yin to clear away the lung-heat, effect of reinforcing stomach reg fluid.Can be used for lung-heat type cough, labor coughs phlegm blood, pyreticosis Tianjin wound is thirsty.
The tuber of dwarf lilyturf: sweet, the micro-hardship of property, is slightly cold.The thoughts of returning home, lung, stomach warp.Have nourishing Yin and promoting production of body fluid, effect that moistening lung clears away heart-fire, can be used for larynx numbness pharyngalgia, Tianjin wound is thirsty, and interior heat is quenched one's thirst, vexed insomnia, the dry constipation of intestines etc.
Selfheal: bitter, pungent, cold in nature.Return liver, gallbladder channel.Have and relieve inflammation or internal heat, improving eyesight, dissipating bind, effect of detumescence, cures mainly red eye, swell pain, and order pearl nyctalgia, has a headache dizzy, scrofula, and goiter and tumor, swells and ache; Thyroid Gland Swell, scrofula, the proliferation of mammary gland, the cards such as hypertension, hyperglycaemia, high fat of blood and high blood are sticky.
Chrysanthemum: cold nature, bitter, pungent.There is effect of dispelling wind, heat-clearing, improving eyesight, removing toxic substances.The disease such as primary treatment headache, dizzy, hot eyes, ambition dysphoria with smothery sensation, furunculosis, pyogenic infections.
Fructus viticis: pungent, bitter, is slightly cold.Return bladder, liver, stomach warp.Dispelling wind and heat from the body, the clear sharp head.For anemopyretic cold headache, gingivitis, the many tear of hot eyes, order is secretly failed to understand, has a dizzy spell.
Tribulus terrestris: bitter, pungent is flat.Return Liver Channel.Flat liver solution is strongly fragrant, dispelling pathogenic wind for improving eyesight.For dizziness due to hyperactivity of liver-YANG headache, liver-depressed hypochondrium pain, headache due to pathogenic wind-heat, red eye, swell pain, the diseases such as pruitus.
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.Raw with solid table, losslessly to send out, to have sweat to stop; Process with bowl spares, beneficial vigour, strong taste.Green blood, myogenic, apocenosis Neto, sore carbuncle panacea.Variola does not rise, and the deficiency of yang should it without hot person.Function shows arrest sweating admittedly, inducing diuresis for removing edema, the apocenosis of holder sore, regulating fluid apssage.
The root of kudzu vine: cool in nature, taste is sweet, pungent.Return spleen, stomach warp.Can rise positive expelling pathogenic factors from muscles and skin, promoting eruption antidiarrheal, relieving restlessness is temperature only.Cure the wound cold, warm headache Xiang Qiang, and dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery, and ecchymosis is not saturating, hypertension, and angina pectoris is deaf.
Scouring rush: taste is sweet, bitter, property is put down.Return lung, Liver Channel.Energy sweating expelling pathogenic factors from muscles and skin, rises loose fiery strongly fragrant rheumatism, controls all blood diseases of eyes also.Cure the wound cold, malaria.Curing rheumatism, loose fire-evil.
Root of Chinese trichosanthes: sweet, micro-hardship, is slightly cold.Attach to the lung and stomach meridians.Clearing heat and promoting fluid, detumescence and apocenosis.
Pipewort: pungent, sweet, cool.Enter liver, stomach warp.Frivolous liter falls apart, and kind evacuation women's head-ornaments wind-heat, removing nebula, attack caused red eye, swell pain, the many tear of photophobia, screen of looking unfamiliar film with controlling in wind-heat.
Butterflybush flower: taste is sweet, cold nature.Return liver, gallbladder channel.Function heat-clearing nourishing the liver, removing nebula.For red eye, swell pain, many tear photophobia, clear liver and improve vision, the raw screen film of order, hepatasthenia dim eyesight, blurring of vision, relieving cough and asthma, beautifying face and moistering lotion.
The seed of Chinese dodder: smell is pungent, sweet, flat nontoxic.Support flesh reinforcing yin essence, hard muscles and bones, stem syncope due to pathogenic cold, essence is from going out, and drown and have the heeltap, bitter taste is yearningly dry, and cold blood is long-pending.Mend general debility, control and let out essence, hematuria, profit cardiopulmonary.
Saline cistanche: sweet, salty, temperature.Return kidney, large intestine channel.Kidney-replenishing, benefiting essence-blood, relaxes bowel.For impotence, infertile, soreness and weakness of waist and knees, muscles and bones is unable, the dry constipation of intestines.
Paris polyphylla: slightly poisonous, bitter, cold.Return Liver Channel.There is the merit of clearing heat and detoxicating, cool liver arresting convulsion, be applicable to multiple pathopyretic ulcer, abscess of throat, mumps, venomous snake bite, frightened epilepsy, unconsciousness due to high fever etc.
Tinosporae: bitter, cold.Return lung, large intestine channel.Function is clearing heat and detoxicating, relieve sore throat, swelling and pain relieving.For abscess of throat, ulcer serious case of furuncle, has loose bowels, dysentery, gastral cavity abdomen heat pain.
Feed vector comprises corn, dregs of beans and wheat.
Feed adhesive comprises Strong flour and starch; In feed adhesive, the ratio of weight and number of each composition is: Strong flour is 20-25 part, and starch is 25-30 part.
The ratio of weight and number of feed vector, feed adhesive and Chinese medicine additive is 100 weight portions: 20-45 weight portion: 4-8 weight portion.
Starch comprises uncooked amylum and ripe starch; The ratio of weight and number of uncooked amylum and ripe starch is: 40-50 part: 15-25 part; Strong flour is the flour that protein wt degree is greater than 20%.
In Chinese medicine additive, the ratio of weight and number of various bulk drug is: great burdock achene 20-32 part, capsule of weeping forsythia 11-18 part, balloonflower root 18-26 part, schizonepeta 22-33 part, radix scrophulariae 18-22 part, root of large-flowered skullcap 27-35 part, coptis 13-23 part, Radix Isatidis 20-30 part, mulberry leaf 23-30 part, almond 15-30 part, the root of straight ladybell 8-14 part, the tuber of dwarf lilyturf 14-20 part, selfheal 14-22 part, chrysanthemum 26-36 part, fructus viticis 28-35 part, tribulus terrestris 27-33 part, Radix Astragali 15-25 part, root of kudzu vine 25-35 part, scouring rush 20-33 part, root of Chinese trichosanthes 28-32 part, pipewort 22-30 part, butterflybush flower 17-25 part, seed of Chinese dodder 10-18 part, saline cistanche 15-25 part, Paris polyphylla 22-32 part and tinosporae 27-35 part.
In feed vector, the ratio of weight and number of each component is: corn 30-45 part, dregs of beans 20-45 part, wheat 30-50 part.
Present invention also offers a kind of preparation method of the feed for preventing and treating duck oromeningitis, comprising:
(1) take all bulk drug mixed grindings according to percentage by weight and become 140-200 order fine powder, be prepared into Chinese medicine additive;
(2) get feed adhesive in proportion, then add and be the water of 30-35% relative to feed adhesive weight ratio and stir, whipping temp is 75-82 DEG C, and the mixture after stirring is poured in spraying machine;
(3) get described feed vector in proportion to pulverize, grinding particle size is 300-460mm, and its fine powder amount is reached, and feed vector always expects more than 97%;
(4) feed vector after described step (3) being pulverized is poured in spraying machine, and the feed adhesive after stirring with step (2) mixes, and in spray, water temperature is 70-86 DEG C, opens spraying machine, stirs 10-12 minute, continues to be warming up to 95 DEG C and complete expanded;
(5) the expanded product that obtains of pulverising step (4), then the Chinese medicine additive adding that step (1) obtains, obtain mixture, add the water of parts by weight 8-15 part of the mixture relative to 100 weight portions, put into granulator and granulate;
(6) dry after granulating, baking temperature is 102 DEG C-115 DEG C, drying time 25-40min; Then cool, pack.
Present invention also offers a kind of Chinese medicine composition for preventing and treating duck oromeningitis, in Chinese medicine composition, the ratio of weight and number of each bulk drug is: great burdock achene 18-37 part, capsule of weeping forsythia 9-20 part, balloonflower root 16-30 part, schizonepeta 20-35 part, radix scrophulariae 15-25 part, root of large-flowered skullcap 25-38 part, coptis 10-23 part, Radix Isatidis 17-30 part, mulberry leaf 23-36 part, almond 15-35 part, the root of straight ladybell 8-18 part, the tuber of dwarf lilyturf 12-24 part, selfheal 12-26 part, chrysanthemum 26-40 part, fructus viticis 28-40 part, tribulus terrestris 25-37 part, Radix Astragali 13-27 part, root of kudzu vine 23-35 part, scouring rush 16-33 part, root of Chinese trichosanthes 26-35 part, pipewort 22-35 part, butterflybush flower 15-30 part, seed of Chinese dodder 7-20 part, saline cistanche 13-28 part, Paris polyphylla 20-35 part and tinosporae 25-38 part.
The preparation method of Chinese traditional medicine composition composition powders comprises
Step one, all bulk drugs are dropped in proportion in mixer stir, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6-1Mpa process, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition added again relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6Mpa-1Mpa process, filter and obtain the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
The toxicity test of embodiment 1 Chinese medicine composition of the present invention
Get great burdock achene 20g, capsule of weeping forsythia 13g, balloonflower root 20g, schizonepeta 25g, radix scrophulariae 19g, root of large-flowered skullcap 34g, coptis 22g, Radix Isatidis 27g, mulberry leaf 29g, almond 16g, the root of straight ladybell 9g, the tuber of dwarf lilyturf 18g, selfheal 15g, chrysanthemum 35g, fructus viticis 30g, tribulus terrestris 32g, Radix Astragali 19g, root of kudzu vine 28g, scouring rush 23g, root of Chinese trichosanthes 29g, pipewort 25g, butterflybush flower 19g, seed of Chinese dodder 11g, saline cistanche 16g, Paris polyphylla 30g and tinosporae 34g; After mixing, pulverize, in the mixture after pulverizing, add the water of 1200g, decoct 2.5 hours, filter, the water adding 500g in filter residue decocts 1.5 hours again, filters, and by twice filtrate mixing, is evaporated to the decoction that crude drug concentration is 3g/ml.
Get ICR mouse, body weight, at 25-30 gram, by body weight random packet, often organizes 10, male and female half and half, oral administration solution administration, and dosage is only 6.0ml/.Continuous Observation 20 days after administration, all mouse of result are strong deposits, and its activity, diet, hair, excreta are no abnormal, have no toxic reaction.Irritation test is carried out to white mouse oral cavity and damaged skin, there are no irritative response and other bad reaction.
Toxicity test proves, the not toxic effect of this medicine and bad reaction, clinical practice is safe and reliable.
Embodiment 2 Chinese medicine composition 1 of the present invention and preparation method
Get great burdock achene 27g, capsule of weeping forsythia 15g, balloonflower root 23g, schizonepeta 30g, radix scrophulariae 21g, root of large-flowered skullcap 28g, coptis 15g, Radix Isatidis 23g, mulberry leaf 24g, almond 20g, the root of straight ladybell 12g, the tuber of dwarf lilyturf 16g, selfheal 20g, chrysanthemum 28g, fructus viticis 34g, tribulus terrestris 28g, Radix Astragali 24g, root of kudzu vine 35g, scouring rush 32g, root of Chinese trichosanthes 31g, pipewort 28g, butterflybush flower 24g, seed of Chinese dodder 17g, saline cistanche 24g, Paris polyphylla 25g and tinosporae 28g; Drop into stirring in mixer, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing loaded in multi-function extractor, add relative to its quality 6 times amount water, boil 3 hours, steam pressure is 0.6Mpa process, filter, obtain the first filtered fluid and filter residue; The filter residue of acquisition is added again relative to its quality 5 times amount water, boil 2 hours, steam pressure is 1Mpa process, filter and obtain the second filtered fluid and filter residue; First filtered fluid and the second filtered fluid are merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
Embodiment 3 Chinese medicine composition 2 of the present invention and preparation method
Get great burdock achene 30g, capsule of weeping forsythia 17g, balloonflower root 25g, schizonepeta 32g, radix scrophulariae 20g, root of large-flowered skullcap 32g, coptis 18g, Radix Isatidis 25g, mulberry leaf 28g, almond 25g, the root of straight ladybell 13g, the tuber of dwarf lilyturf 17g, selfheal 21g, chrysanthemum 30g, fructus viticis 32g, tribulus terrestris 31g, Radix Astragali 22g, root of kudzu vine 33g, scouring rush 27g, root of Chinese trichosanthes 30g, pipewort 23g, butterflybush flower 22g, seed of Chinese dodder 14g, saline cistanche 22g, Paris polyphylla 26g and tinosporae 31g; Drop into stirring in mixer, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing loaded in multi-function extractor, add relative to its quality 7 times amount water, boil 4 hours, steam pressure is 0.8Mpa process, filter, obtain the first filtered fluid and filter residue; The filter residue of acquisition is added again relative to its quality 5 times amount water, boil 3 hours, steam pressure is 1Mpa process, filter and obtain the second filtered fluid and filter residue; First filtered fluid and the second filtered fluid are merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
Embodiment 4 Chinese medicine composition 3 of the present invention and preparation method
Get great burdock achene 23g, capsule of weeping forsythia 12g, balloonflower root 19g, schizonepeta 27g, radix scrophulariae 22g, root of large-flowered skullcap 33g, coptis 16g, Radix Isatidis 22g, mulberry leaf 27g, almond 28g, the root of straight ladybell 11g, the tuber of dwarf lilyturf 15g, selfheal 17g, chrysanthemum 33g, fructus viticis 29g, tribulus terrestris 30g, Radix Astragali 16g, root of kudzu vine 26g, scouring rush 30g, root of Chinese trichosanthes 28g, pipewort 30g, butterflybush flower 25g, seed of Chinese dodder 13g, saline cistanche 20g, Paris polyphylla 28g and tinosporae 33g; Drop into stirring in mixer, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing loaded in multi-function extractor, add relative to its quality 6 times amount water, boil 3 hours, steam pressure is 0.9Mpa process, filter, obtain the first filtered fluid and filter residue; The filter residue of acquisition is added again relative to its quality 6 times amount water, boil 3 hours, steam pressure is 0.9Mpa process, filter and obtain the second filtered fluid and filter residue; First filtered fluid and the second filtered fluid are merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
Embodiment 5 feed 1 of the present invention and preparation method
A kind of feed, comprise feed vector, feed adhesive and Chinese medicine additive, its ratio of weight and number is 100 weight portions: 20 weight portions: 8 weight portions, wherein, in feed vector, each component and weight are corn 3000g, dregs of beans 4000g, wheat 5000g, wherein, the Chinese medicine composition powder 1 of Chinese medicine additive Example 2 preparation is for subsequent use.
The preparation method of feed is as follows: get feed adhesive in proportion, and then add and be the water of 30% relative to feed adhesive weight ratio and stir, whipping temp is 75 DEG C, and the mixture after stirring is poured in spraying machine; Get described feed vector in proportion to pulverize, grinding particle size is 300mm, and its fine powder amount is reached, and feed vector always expects more than 97%; Pour in spraying machine by the feed vector after pulverizing, mix with the feed adhesive after stirring, in spraying machine, water temperature is 78 DEG C, opens spraying machine, stirs 12 minutes, continues to be warming up to 95 DEG C and completes expanded; Pulverize expanded product, then add Chinese medicine additive (i.e. the Chinese medicine composition powder 1 of embodiment 2), obtain mixture, add the water of the parts by weight 8 parts relative to the mixture of 100 weight portions, put into granulator and granulate; Dry after granulating, baking temperature is 102 DEG C, drying time 25min; Then cool, pack.
Embodiment 6 feed 2 of the present invention and preparation method
A kind of feed, comprise feed vector, feed adhesive and Chinese medicine additive, its ratio of weight and number is 100 weight portions: 20 weight portions: 8 weight portions, wherein, in feed vector, each component and weight are corn 3000g, dregs of beans 4000g, wheat 5000g, wherein, the Chinese medicine composition powder 2 of Chinese medicine additive Example 3 preparation is for subsequent use.
The preparation method of feed is as follows: get feed adhesive in proportion, and then add and be the water of 35% relative to feed adhesive weight ratio and stir, whipping temp is 80 DEG C, and the mixture after stirring is poured in spraying machine; Get described feed vector in proportion to pulverize, grinding particle size is 350mm, and its fine powder amount is reached, and feed vector always expects more than 97%; Pour in spraying machine by the feed vector after pulverizing, mix with the feed adhesive after stirring, in spraying machine, water temperature is 86 DEG C, opens spraying machine, stirs 10 minutes, continues to be warming up to 95 DEG C and completes expanded; Pulverize expanded product, then add Chinese medicine additive (i.e. the Chinese medicine composition powder 2 of embodiment 3), obtain mixture, add the water of the parts by weight 10 parts relative to the mixture of 100 weight portions, put into granulator and granulate; Dry after granulating, baking temperature is 110 DEG C, drying time 30min; Then cool, pack.
Embodiment 7 clinical testing
(1) for examination animal
Be selected to natural infection in 7 duckeries of city, Leshan, Nanchong City, the sick duck of doubtful scrositis carries out bacteria distribution; From the sick duck after making a definite diagnosis, random selecting 600 sick duck in 2 week age is as treatment contrast test object; Another from 7 duckeries of Chengdu, Leshan, Nanchong City random selecting 600 healthy duck in 4 weeks age as preventing contrast test object.
(2) bacterial strain extracts and cultivates:
Cut open inspection to 40 ducks that die of illness in 7 duckeries of Chengdu, Leshan, Nanchong City, the die of illness internal organs such as the heart, liver, brain of duck of aseptic collection are smeared and are inoculated in chocolate dull and stereotyped 4 parts, put into candle cylinder for 2 parts, Anaerobic culturel 48h at 37 DEG C; 2 parts put into 37 DEG C at incubator cultivate; Then purifying is carried out to the doubtful bacterium colony good at grow on plates.The colony inoculation getting purifying in the mid-37 DEG C of shaken cultivation casees of serum improvement meat soup cultivate 24 hours for subsequent use.
(3) contrast experiment is prevented:
Healthy for 600 of random choose 4 week ages duck is divided into 3 groups (control group 1, control group 2 and embodiment groups) at random, wherein, control group 1 and control group 2 use traditional duck feed to feed meat duck respectively, embodiment group uses the feed 1 in embodiment 5 to feed duck, feed after 7 days, carry out the 5 times dilutions of artificial challenge with culture for subsequent use to control group 1 and embodiment group, lumbar injection 0.2mL/ only, observed and recorded respectively organizes the incidence of disease and the death rate of duck, and result is as shown in table 1.
The table 1 preventive effect table of comparisons
Data from table 1: the feed that the present invention contains Chinese medicine composition has obvious preventive effect to duck oromeningitis.
(4) contrast test is treated:
Curative effect determinate standard
Cure: sick duck clinical symptoms disappear completely, every physical signs is recovered normal (spirit, appetite, breathing, drinking-water, ight soil etc.), all belongs to healing;
Effective: after medication is treated, sick duck cardinal symptom is alleviated, symptom obviously alleviates, spiritual and diet is effective for treating for improvement person;
Invalid: sick duck clinical symptoms are without being clearly better, and the typical cytopathic of duck oromeningitis, appears in even aggravation, finally dead.
Efficient is cure rate and obvious effective rate sum.
Be divided at random 3 groups (treatment by Chinese herbs group, western medicine group, blank groups) by sick for 600 of random selecting 2 week ages duck, treat with different medicine, wherein, treatment by Chinese herbs group selects the Chinese medicine composition 3 of embodiment 4, dose be every every day 0.6g; Western medicine group selects enrofloxacin injection 15mg/kg to carry out neck injection; Blank group does not feed any medicine.Observed and recorded respectively organizes cure rate and the death rate of duck, and result is as shown in table 2.
The table 2 result for the treatment of table of comparisons
Data from table 2: Chinese medicine composition of the present invention is obviously better than western medicine group to the result for the treatment of of duck oromeningitis, reduce the death rate, improve cure rate.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (9)
1. one kind for preventing and treating the feed of duck oromeningitis, it is characterized in that, comprise feed vector, feed adhesive and Chinese medicine additive, in described Chinese medicine additive, the ratio of weight and number of each bulk drug is: great burdock achene 18-37 part, capsule of weeping forsythia 9-20 part, balloonflower root 16-30 part, schizonepeta 20-35 part, radix scrophulariae 15-25 part, root of large-flowered skullcap 25-38 part, coptis 10-23 part, Radix Isatidis 17-30 part, mulberry leaf 23-36 part, almond 15-35 part, the root of straight ladybell 8-18 part, the tuber of dwarf lilyturf 12-24 part, selfheal 12-26 part, chrysanthemum 26-40 part, fructus viticis 28-40 part, tribulus terrestris 25-37 part, Radix Astragali 13-27 part, root of kudzu vine 23-35 part, scouring rush 16-33 part, root of Chinese trichosanthes 26-35 part, pipewort 22-35 part, butterflybush flower 15-30 part, seed of Chinese dodder 7-20 part, saline cistanche 13-28 part, Paris polyphylla 20-35 part and tinosporae 25-38 part.
2. the feed for preventing and treating duck oromeningitis according to claim 1, is characterized in that, described feed vector comprises corn, dregs of beans and wheat.
3. the feed for preventing and treating duck oromeningitis according to claim 1, is characterized in that, described feed adhesive comprises Strong flour and starch; In described feed adhesive, the ratio of weight and number of Strong flour and starch is: Strong flour is 20-25 part, and starch is 25-30 part.
4. the feed for preventing and treating duck oromeningitis according to claim 1, is characterized in that, the ratio of weight and number of described feed vector, feed adhesive and Chinese medicine additive is 100 weight portions: 20-45 weight portion: 4-8 weight portion.
5. the feed for preventing and treating duck oromeningitis according to claim 3, is characterized in that, described starch comprises uncooked amylum and ripe starch; The ratio of weight and number of described uncooked amylum and described ripe starch is 40-50 part: 15-25 part; Described Strong flour is the flour that protein wt degree is greater than 20%.
6. according to the arbitrary described feed for preventing and treating duck oromeningitis of claim 1-5, it is characterized in that, in described Chinese medicine additive, the ratio of weight and number of each bulk drug is: great burdock achene 20-32 part, capsule of weeping forsythia 11-18 part, balloonflower root 18-26 part, schizonepeta 22-33 part, radix scrophulariae 18-22 part, root of large-flowered skullcap 27-35 part, coptis 13-23 part, Radix Isatidis 20-30 part, mulberry leaf 23-30 part, almond 15-30 part, the root of straight ladybell 8-14 part, the tuber of dwarf lilyturf 14-20 part, selfheal 14-22 part, chrysanthemum 26-36 part, fructus viticis 28-35 part, tribulus terrestris 27-33 part, Radix Astragali 15-25 part, root of kudzu vine 25-35 part, scouring rush 20-33 part, root of Chinese trichosanthes 28-32 part, pipewort 22-30 part, butterflybush flower 17-25 part, seed of Chinese dodder 10-18 part, saline cistanche 15-25 part, Paris polyphylla 22-32 part and tinosporae 27-35 part.
7., according to the arbitrary described feed for preventing and treating duck oromeningitis of claim 1-5, it is characterized in that, in described feed vector, the ratio of weight and number of each component is: corn 30-45 part, dregs of beans 20-45 part, wheat 30-50 part.
8. one kind for preventing and treating the Chinese medicine composition of duck oromeningitis, it is characterized in that, in described Chinese medicine composition, the ratio of weight and number of each bulk drug is: great burdock achene 18-37 part, capsule of weeping forsythia 9-20 part, balloonflower root 16-30 part, schizonepeta 20-35 part, radix scrophulariae 15-25 part, root of large-flowered skullcap 25-38 part, coptis 10-23 part, Radix Isatidis 17-30 part, mulberry leaf 23-36 part, almond 15-35 part, the root of straight ladybell 8-18 part, the tuber of dwarf lilyturf 12-24 part, selfheal 12-26 part, chrysanthemum 26-40 part, fructus viticis 28-40 part, tribulus terrestris 25-37 part, Radix Astragali 13-27 part, root of kudzu vine 23-35 part, scouring rush 16-33 part, root of Chinese trichosanthes 26-35 part, pipewort 22-35 part, butterflybush flower 15-30 part, seed of Chinese dodder 7-20 part, saline cistanche 13-28 part, Paris polyphylla 20-35 part and tinosporae 25-38 part.
9. the Chinese medicine composition for preventing and treating duck oromeningitis according to claim 8, is characterized in that, the preparation method of described Chinese traditional medicine composition composition powders comprises:
Step one, all bulk drugs are dropped in proportion in mixer stir, mixing, pulverize in rear feeding pulverizer, the Chinese medicine composition after pulverizing is loaded in multi-function extractor, add relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6-1Mpa process, filter, obtain the first filtered fluid and filter residue;
Step 2, the filter residue of acquisition added again relative to its quality 5-7 times amount water, boil 2-4 hour, steam pressure is 0.6Mpa-1Mpa process, filter and obtain the second filtered fluid and filter residue;
Step 3, the first filtered fluid and the second filtered fluid merged, concentrated removing moisture, obtains and gets dry extract, and adopts super-fine powder mill to pulverize, is crushed to less than 30 μm, obtain Chinese medicine additive powder.
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| CN105639105A (en) * | 2016-01-05 | 2016-06-08 | 刘华武 | Wanxi white goose feed additive |
| CN108208343A (en) * | 2018-01-09 | 2018-06-29 | 重庆市家云孔雀养殖有限公司 | A kind of feed for preventing peacock influenza and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN102908549A (en) * | 2012-11-14 | 2013-02-06 | 蒋常德 | Chinese herbal medicine active fermentation health care liquid for preventing and treating bird flu and preparation method of same |
| CN103202894A (en) * | 2013-04-01 | 2013-07-17 | 陈鹏举 | Chinese herbal medicine feed additive for preventing and curing infectious serositis of duck |
| CN103211985A (en) * | 2013-05-03 | 2013-07-24 | 青岛农业大学 | Traditional Chinese medicine for treating infectious serositis of duck |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN102908549A (en) * | 2012-11-14 | 2013-02-06 | 蒋常德 | Chinese herbal medicine active fermentation health care liquid for preventing and treating bird flu and preparation method of same |
| CN103202894A (en) * | 2013-04-01 | 2013-07-17 | 陈鹏举 | Chinese herbal medicine feed additive for preventing and curing infectious serositis of duck |
| CN103211985A (en) * | 2013-05-03 | 2013-07-24 | 青岛农业大学 | Traditional Chinese medicine for treating infectious serositis of duck |
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