CN104350155B - 用于生产甲基丙烯酸甲酯的方法 - Google Patents

用于生产甲基丙烯酸甲酯的方法 Download PDF

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Publication number
CN104350155B
CN104350155B CN201380028228.5A CN201380028228A CN104350155B CN 104350155 B CN104350155 B CN 104350155B CN 201380028228 A CN201380028228 A CN 201380028228A CN 104350155 B CN104350155 B CN 104350155B
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CN
China
Prior art keywords
monooxygenase
baeyer
villiger
cyclohexanone
methyl
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Expired - Fee Related
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CN201380028228.5A
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English (en)
Chinese (zh)
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CN104350155A (zh
Inventor
格雷厄姆·罗纳德·伊斯特汉
大卫·威廉·约翰逊
阿德里安努斯·约翰尼斯·约瑟夫·斯塔索夫
马克·威廉默斯·弗拉杰
雷姆科·特斯基比·温特
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Mitsubishi Chemical UK Ltd
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Lucite International UK Ltd
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Expired - Fee Related legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10—Esters
    • C08F20/12—Esters of monohydric alcohols or phenols
    • C08F20/14—Methyl esters, e.g. methyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0073—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C12Y114/13022—Cyclohexanone monooxygenase (1.14.13.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C12Y114/13084—4-Hydroxyacetophenone monooxygenase (1.14.13.84)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C12Y114/13092—Phenylacetone monooxygenase (1.14.13.92)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
CN201380028228.5A 2012-05-28 2013-05-24 用于生产甲基丙烯酸甲酯的方法 Expired - Fee Related CN104350155B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201209425A GB201209425D0 (en) 2012-05-28 2012-05-28 Process for production of methyl methacrylate
GB1209425.6 2012-05-28
PCT/GB2013/051376 WO2013179005A1 (en) 2012-05-28 2013-05-24 Process for the production of methyl methacrylate

Publications (2)

Publication Number Publication Date
CN104350155A CN104350155A (zh) 2015-02-11
CN104350155B true CN104350155B (zh) 2017-10-31

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CN201380028228.5A Expired - Fee Related CN104350155B (zh) 2012-05-28 2013-05-24 用于生产甲基丙烯酸甲酯的方法

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Country Link
US (1) US9816115B2 (https=)
EP (1) EP2855689B1 (https=)
JP (2) JP2015519062A (https=)
KR (1) KR20150027141A (https=)
CN (1) CN104350155B (https=)
AR (1) AR091181A1 (https=)
AU (1) AU2013269391B2 (https=)
BR (1) BR112014029726A2 (https=)
CA (1) CA2873620A1 (https=)
EA (1) EA201492264A1 (https=)
ES (1) ES2733758T3 (https=)
GB (1) GB201209425D0 (https=)
IN (1) IN2014DN10494A (https=)
MX (1) MX2014014370A (https=)
MY (1) MY169813A (https=)
SG (1) SG11201407711QA (https=)
TW (1) TW201400617A (https=)
WO (1) WO2013179005A1 (https=)
ZA (1) ZA201408554B (https=)

Families Citing this family (7)

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Publication number Priority date Publication date Assignee Title
CN105368737B (zh) * 2015-09-21 2018-05-25 中海油天津化工研究设计院有限公司 一种处理高浓度有机废水的菌株、微生物菌剂及其应用
WO2019048438A1 (en) 2017-09-05 2019-03-14 Vito Nv IN SITU PRODUCT RECOVERY METHOD AND APPARATUS
CN108300707B (zh) * 2018-02-07 2019-09-13 凯莱英医药集团（天津）股份有限公司 一种单加氧酶突变体及其制备方法和应用
EP3957724A4 (en) * 2019-04-17 2023-05-31 Asymchem Life Science (Tianjin) Co., Ltd TRANSAMINASE MUTANT AND USE THEREOF
CN110591984B (zh) * 2019-10-30 2021-05-04 浙江大学 可降解甲苯、二甲苯与丙烯酸水混合废水的混合菌剂及其应用
US11814738B2 (en) * 2020-01-30 2023-11-14 Avantium Knowledge Centre B.V. Electrochemical production of formate
GB202010072D0 (en) * 2020-07-01 2020-08-12 Givaudan Sa Enzyme-mediated process

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2011077140A2 (en) * 2009-12-21 2011-06-30 Lucite International Uk Limited Method of producing acrylic and methacrylic acid

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GB1428277A (en) 1972-08-03 1976-03-17 Monsanto Co Production of unsaturated acids and esters
DE3004467A1 (de) 1980-02-07 1981-08-13 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von methylmethacrylat durch umsetzung von methylpropionat und methanol
JP2901008B2 (ja) 1989-11-28 1999-06-02 明治乳業株式会社 乳酸菌によるジアセチル、アセトイン発酵法
AU689626B2 (en) 1994-07-25 1998-04-02 Boehringer Mannheim Gmbh Peptides marked with metal chelates
US5753474A (en) 1995-12-26 1998-05-19 Environmental Energy, Inc. Continuous two stage, dual path anaerobic fermentation of butanol and other organic solvents using two different strains of bacteria
WO2000009682A1 (en) 1998-08-12 2000-02-24 Maxygen, Inc. Dna shuffling of monooxygenase genes for production of industrial chemicals
US7105296B2 (en) 2001-08-29 2006-09-12 E. I. Du Pont De Nemours And Company Genes encoding Baeyer-Villiger monooxygenases
WO2004007750A2 (en) 2002-07-11 2004-01-22 Diversa Corporation Monooxygenases, nucleic acids encoding them and methods for making and using them
US8206970B2 (en) 2006-05-02 2012-06-26 Butamax(Tm) Advanced Biofuels Llc Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase
US7541173B2 (en) 2006-06-15 2009-06-02 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
DE102006039189B4 (de) * 2006-08-21 2010-07-29 Ernst-Moritz-Arndt-Universität Greifswald Enantioselektive Darstellung von aliphatischen azyklischen Estern und Ketonen
DE102007050762B3 (de) 2007-10-22 2009-05-07 Heraeus Medical Gmbh Pastenförmiger Polymethylmethacrylat-Knochenzement und seine Verwendung
US8119844B2 (en) 2008-05-01 2012-02-21 Lanzatech New Zealand Limited Alcohol production process
FR2940801B1 (fr) 2009-01-06 2012-08-17 Arkema France Procede de fabrication d'un methacrylate de methyle derive de la biomasse
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WO2011077140A2 (en) * 2009-12-21 2011-06-30 Lucite International Uk Limited Method of producing acrylic and methacrylic acid

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Also Published As

Publication number Publication date
JP6571749B2 (ja) 2019-09-04
KR20150027141A (ko) 2015-03-11
SG11201407711QA (en) 2014-12-30
EP2855689B1 (en) 2019-04-03
IN2014DN10494A (https=) 2015-08-21
WO2013179005A1 (en) 2013-12-05
MX2014014370A (es) 2015-02-05
CA2873620A1 (en) 2013-12-05
AR091181A1 (es) 2015-01-14
EA201492264A1 (ru) 2015-05-29
AU2013269391A1 (en) 2015-01-22
JP2015519062A (ja) 2015-07-09
CN104350155A (zh) 2015-02-11
BR112014029726A2 (pt) 2017-06-27
GB201209425D0 (en) 2012-07-11
EP2855689A1 (en) 2015-04-08
JP2018050637A (ja) 2018-04-05
US9816115B2 (en) 2017-11-14
AU2013269391B2 (en) 2016-12-15
ZA201408554B (en) 2016-04-28
ES2733758T3 (es) 2019-12-02
MY169813A (en) 2019-05-16
US20150112037A1 (en) 2015-04-23
TW201400617A (zh) 2014-01-01

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Granted publication date: 20171031

Termination date: 20200524