CN1043348C - 不对称取代的黄嘌呤、其制备方法及其作为药物组合物的应用 - Google Patents

不对称取代的黄嘌呤、其制备方法及其作为药物组合物的应用 Download PDF

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Publication number
CN1043348C
CN1043348C CN93109282A CN93109282A CN1043348C CN 1043348 C CN1043348 C CN 1043348C CN 93109282 A CN93109282 A CN 93109282A CN 93109282 A CN93109282 A CN 93109282A CN 1043348 C CN1043348 C CN 1043348C
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general formula
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Expired - Fee Related
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CN93109282A
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Chinese (zh)
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CN1086818A (zh
Inventor
乌瑞克·库克诺-穆尔
赫尔曼特·恩森格
约切姆·米耶雷
弗朗兹·约瑟夫·库
埃里奇·莱尔
恩齐欧·米勒
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Boehringer Ingelheim GmbH
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Boehringer Ingelheim GmbH
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Publication of CN1086818A publication Critical patent/CN1086818A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Laser Surgery Devices (AREA)
  • Radiation-Therapy Devices (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
CN93109282A 1992-08-10 1993-08-10 不对称取代的黄嘌呤、其制备方法及其作为药物组合物的应用 Expired - Fee Related CN1043348C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DEP4226371.9 1992-08-10
DE4226371 1992-08-10
DE4238423 1992-11-13
DEP4238423.0 1992-11-13

Publications (2)

Publication Number Publication Date
CN1086818A CN1086818A (zh) 1994-05-18
CN1043348C true CN1043348C (zh) 1999-05-12

Family

ID=25917371

Family Applications (1)

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CN93109282A Expired - Fee Related CN1043348C (zh) 1992-08-10 1993-08-10 不对称取代的黄嘌呤、其制备方法及其作为药物组合物的应用

Country Status (21)

Country Link
US (1) US5719279A (cg-RX-API-DMAC10.html)
EP (1) EP0654033A1 (cg-RX-API-DMAC10.html)
JP (1) JPH08500344A (cg-RX-API-DMAC10.html)
KR (1) KR950702988A (cg-RX-API-DMAC10.html)
CN (1) CN1043348C (cg-RX-API-DMAC10.html)
AU (1) AU681348B2 (cg-RX-API-DMAC10.html)
BG (1) BG62618B1 (cg-RX-API-DMAC10.html)
CA (1) CA2140883A1 (cg-RX-API-DMAC10.html)
CZ (1) CZ286459B6 (cg-RX-API-DMAC10.html)
FI (1) FI950542A0 (cg-RX-API-DMAC10.html)
HU (1) HUT65734A (cg-RX-API-DMAC10.html)
IL (1) IL106624A (cg-RX-API-DMAC10.html)
MX (1) MX9304819A (cg-RX-API-DMAC10.html)
NZ (1) NZ254804A (cg-RX-API-DMAC10.html)
PL (1) PL176389B1 (cg-RX-API-DMAC10.html)
RU (1) RU2138500C1 (cg-RX-API-DMAC10.html)
SG (1) SG55038A1 (cg-RX-API-DMAC10.html)
SK (1) SK18595A3 (cg-RX-API-DMAC10.html)
TW (1) TW252044B (cg-RX-API-DMAC10.html)
UA (1) UA46697C2 (cg-RX-API-DMAC10.html)
WO (1) WO1994003456A1 (cg-RX-API-DMAC10.html)

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Also Published As

Publication number Publication date
TW252044B (cg-RX-API-DMAC10.html) 1995-07-21
PL307397A1 (en) 1995-05-15
RU2138500C1 (ru) 1999-09-27
BG62618B1 (bg) 2000-03-31
BG99489A (bg) 1996-01-31
SG55038A1 (en) 1998-12-21
CZ34895A3 (en) 1995-10-18
JPH08500344A (ja) 1996-01-16
CZ286459B6 (en) 2000-04-12
FI950542L (fi) 1995-02-08
FI950542A7 (fi) 1995-02-08
NZ254804A (en) 1997-01-29
US5719279A (en) 1998-02-17
EP0654033A1 (de) 1995-05-24
HU9302302D0 (en) 1993-10-28
WO1994003456A1 (de) 1994-02-17
CN1086818A (zh) 1994-05-18
RU95109100A (ru) 1996-12-27
PL176389B1 (pl) 1999-05-31
MX9304819A (es) 1994-02-28
FI950542A0 (fi) 1995-02-08
SK18595A3 (en) 1995-07-11
KR950702988A (ko) 1995-08-23
AU4707193A (en) 1994-03-03
HUT65734A (en) 1994-07-28
UA46697C2 (uk) 2002-06-17
CA2140883A1 (en) 1994-02-17
IL106624A (en) 1999-01-26
AU681348B2 (en) 1997-08-28
IL106624A0 (en) 1993-12-08

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