CN104093754B - 用于储存并递送活性剂的聚合物粒子 - Google Patents

用于储存并递送活性剂的聚合物粒子 Download PDF

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Publication number
CN104093754B
CN104093754B CN201280055438.9A CN201280055438A CN104093754B CN 104093754 B CN104093754 B CN 104093754B CN 201280055438 A CN201280055438 A CN 201280055438A CN 104093754 B CN104093754 B CN 104093754B
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monomer
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poly
polymer particles
propylene glycol
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CN201280055438.9A
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CN104093754A (zh
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H·萨霍亚尼
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3M Innovative Properties Co
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3M Innovative Properties Co
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C08F220/301—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety and one oxygen in the alcohol moiety
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/12—Polymerisation in non-solvents
    • C08F2/16—Aqueous medium
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/106—Esters of polycondensation macromers
    • C08F222/1063—Esters of polycondensation macromers of alcohol terminated polyethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/26—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/103—Esters of polyhydric alcohols or polyhydric phenols of trialcohols, e.g. trimethylolpropane tri(meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2201/00—Foams characterised by the foaming process
    • C08J2201/04—Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
    • C08J2201/046—Elimination of a polymeric phase
    • C08J2201/0462—Elimination of a polymeric phase using organic solvents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2333/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
    • C08J2333/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
CN201280055438.9A 2011-11-21 2012-11-01 用于储存并递送活性剂的聚合物粒子 Expired - Fee Related CN104093754B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161561997P 2011-11-21 2011-11-21
US61/561,997 2011-11-21
PCT/US2012/063004 WO2013077981A1 (en) 2011-11-21 2012-11-01 Polymeric particles for storage and delivery of active agents

Publications (2)

Publication Number Publication Date
CN104093754A CN104093754A (zh) 2014-10-08
CN104093754B true CN104093754B (zh) 2017-06-23

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US (1) US9827318B2 (enExample)
EP (1) EP2782941B1 (enExample)
JP (1) JP6127061B2 (enExample)
CN (1) CN104093754B (enExample)
WO (1) WO2013077981A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105209024B (zh) 2013-05-17 2018-04-27 3M创新有限公司 生物活性剂从聚合物复合颗粒的释放
JP6346662B2 (ja) 2013-05-17 2018-06-20 スリーエム イノベイティブ プロパティズ カンパニー 反応混合物、多孔質粒子及び作製方法
US10413881B2 (en) 2013-12-18 2019-09-17 3M Innovative Properties Company Porous articles for separation
WO2016053830A1 (en) 2014-10-01 2016-04-07 3M Innovative Properties Company Articles including fibrous substrates and porous polymeric particles and methods of making same
US10286100B2 (en) 2014-10-01 2019-05-14 3M Innovative Properties Company Medical dressings comprising fluid management articles and methods of using same
JP6975640B2 (ja) 2015-03-06 2021-12-01 スリーエム イノベイティブ プロパティズ カンパニー 多孔質ポリマー粒子を含む組成物及び接着剤物品、並びに基材をコーティングする方法
US20180057770A1 (en) 2015-03-23 2018-03-01 3M Innovative Properties Company Polymeric composite particles
US10913834B2 (en) 2017-11-16 2021-02-09 3M Innovative Properties Company Polymer matrix composites comprising indicator particles and methods of making the same
CN111447993A (zh) 2017-11-16 2020-07-24 3M创新有限公司 包含官能化颗粒的聚合物基质复合材料及其制备方法
US10836873B2 (en) 2017-11-16 2020-11-17 3M Innovative Properties Company Polymer matrix composites comprising thermally insulating particles and methods of making the same
WO2019097449A1 (en) 2017-11-16 2019-05-23 3M Innovative Properties Company Method of making polymer matrix composites
US10927228B2 (en) 2017-11-16 2021-02-23 3M Innovative Properties Company Polymer matrix composites comprising intumescent particles and methods of making the same
CN111372677A (zh) 2017-11-16 2020-07-03 3M创新有限公司 包含可溶性颗粒或可溶胀颗粒中的至少一种的聚合物基质复合材料及其制备方法
US11732104B2 (en) 2017-11-16 2023-08-22 3M Innovative Properties Company Polymer matrix composites comprising dielectric particles and methods of making the same
WO2019210428A1 (en) * 2018-05-03 2019-11-07 The University Of British Columbia Cell encapsulation compositions and methods for immunocytochemistry
CN116888198A (zh) * 2021-02-05 2023-10-13 花王株式会社 水凝胶结构体

Citations (2)

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CN101293192A (zh) * 2007-01-25 2008-10-29 中国科学院上海硅酸盐研究所 多室囊泡模板法制备多层空心球或多孔球的方法
CN101910268A (zh) * 2007-11-09 2010-12-08 3M创新有限公司 多孔聚合物树脂

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US4743545A (en) 1984-08-09 1988-05-10 Torobin Leonard B Hollow porous microspheres containing biocatalyst
US4303736A (en) 1979-07-20 1981-12-01 Leonard Torobin Hollow plastic microspheres
JPS608306A (ja) 1983-06-28 1985-01-17 Hitachi Chem Co Ltd 多孔性架橋重合体粒子の製造法
US5045569A (en) 1988-11-30 1991-09-03 Minnesota Mining And Manufacturing Company Hollow acrylate polymer microspheres
JPH05105729A (ja) 1991-10-08 1993-04-27 Tokyo Keikaku:Kk 吸油性樹脂
US5508341A (en) 1993-07-08 1996-04-16 Regents Of The University Of California Organic aerogel microspheres and fabrication method therefor
US5712358A (en) * 1995-06-07 1998-01-27 Amcol International Corporation Process for producing an oil sorbent copolymer and the product thereof
ATE266685T1 (de) 1998-10-02 2004-05-15 Showa Denko Kk Poröse copolymerpartikel, verfahren zu deren herstellung und deren verwendung
JP4734685B2 (ja) * 1998-10-02 2011-07-27 昭和電工株式会社 多孔性共重合体粒子の製造方法
WO2002041987A2 (en) 2000-10-25 2002-05-30 Tufts University Polymeric microspheres
JP3888856B2 (ja) * 2001-03-14 2007-03-07 積水化成品工業株式会社 多孔質樹脂微粒子およびそれを配合した外用剤
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CN101910268A (zh) * 2007-11-09 2010-12-08 3M创新有限公司 多孔聚合物树脂

Also Published As

Publication number Publication date
US9827318B2 (en) 2017-11-28
WO2013077981A1 (en) 2013-05-30
EP2782941A1 (en) 2014-10-01
US20140309314A1 (en) 2014-10-16
JP6127061B2 (ja) 2017-05-10
EP2782941B1 (en) 2017-02-22
JP2014533756A (ja) 2014-12-15
CN104093754A (zh) 2014-10-08

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