JP6127061B2 - 活性剤の貯蔵及び送達のための重合体粒子 - Google Patents

活性剤の貯蔵及び送達のための重合体粒子 Download PDF

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JP6127061B2
JP6127061B2 JP2014542329A JP2014542329A JP6127061B2 JP 6127061 B2 JP6127061 B2 JP 6127061B2 JP 2014542329 A JP2014542329 A JP 2014542329A JP 2014542329 A JP2014542329 A JP 2014542329A JP 6127061 B2 JP6127061 B2 JP 6127061B2
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polymer particles
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JP2014533756A5 (enExample
JP2014533756A (ja
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ハッサン サホウアニ,
ハッサン サホウアニ,
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3M Innovative Properties Co
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10Esters
    • C08F220/26Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C08F220/301Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety and one oxygen in the alcohol moiety
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10Macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/12Polymerisation in non-solvents
    • C08F2/16Aqueous medium
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10Esters
    • C08F222/1006Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/106Esters of polycondensation macromers
    • C08F222/1063Esters of polycondensation macromers of alcohol terminated polyethers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/26Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10Esters
    • C08F222/1006Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/103Esters of polyhydric alcohols or polyhydric phenols of trialcohols, e.g. trimethylolpropane tri(meth)acrylate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2201/00Foams characterised by the foaming process
    • C08J2201/04Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
    • C08J2201/046Elimination of a polymeric phase
    • C08J2201/0462Elimination of a polymeric phase using organic solvents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2333/00Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
    • C08J2333/04Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Materials Engineering (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
JP2014542329A 2011-11-21 2012-11-01 活性剤の貯蔵及び送達のための重合体粒子 Active JP6127061B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161561997P 2011-11-21 2011-11-21
US61/561,997 2011-11-21
PCT/US2012/063004 WO2013077981A1 (en) 2011-11-21 2012-11-01 Polymeric particles for storage and delivery of active agents

Publications (3)

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JP2014533756A JP2014533756A (ja) 2014-12-15
JP2014533756A5 JP2014533756A5 (enExample) 2015-11-19
JP6127061B2 true JP6127061B2 (ja) 2017-05-10

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US (1) US9827318B2 (enExample)
EP (1) EP2782941B1 (enExample)
JP (1) JP6127061B2 (enExample)
CN (1) CN104093754B (enExample)
WO (1) WO2013077981A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014186336A1 (en) 2013-05-17 2014-11-20 3M Innovative Properties Company Release of biologically active agents from polymeric composite particles
CN105228820B (zh) 2013-05-17 2017-08-29 3M创新有限公司 反应混合物、多孔粒子以及制备方法
EP3083036B1 (en) 2013-12-18 2020-03-18 3M Innovative Properties Company Porous articles for separation
US10286100B2 (en) 2014-10-01 2019-05-14 3M Innovative Properties Company Medical dressings comprising fluid management articles and methods of using same
JP6646657B2 (ja) 2014-10-01 2020-02-14 スリーエム イノベイティブ プロパティズ カンパニー 繊維性基材及び多孔質ポリマー粒子を含む物品及びその製造方法
US20180044559A1 (en) 2015-03-06 2018-02-15 3M Innovative Properties Company Compositions and adhesive articles including porous polymeric particles and methods of coating substrates
WO2016153748A1 (en) 2015-03-23 2016-09-29 3M Innovative Properties Company Polymeric composite particles
WO2019097446A1 (en) 2017-11-16 2019-05-23 3M Innovative Properties Company Polymer matrix composites comprising functional particles and methods of making the same
JP7317007B2 (ja) 2017-11-16 2023-07-28 スリーエム イノベイティブ プロパティズ カンパニー ポリマーマトリックス複合体の製造方法
US10913834B2 (en) 2017-11-16 2021-02-09 3M Innovative Properties Company Polymer matrix composites comprising indicator particles and methods of making the same
EP3711070A1 (en) 2017-11-16 2020-09-23 3M Innovative Properties Company Polymer matrix composites comprising dielectric particles and methods of making the same
US10836873B2 (en) 2017-11-16 2020-11-17 3M Innovative Properties Company Polymer matrix composites comprising thermally insulating particles and methods of making the same
CN111372677A (zh) 2017-11-16 2020-07-03 3M创新有限公司 包含可溶性颗粒或可溶胀颗粒中的至少一种的聚合物基质复合材料及其制备方法
US10927228B2 (en) 2017-11-16 2021-02-23 3M Innovative Properties Company Polymer matrix composites comprising intumescent particles and methods of making the same
WO2019210428A1 (en) * 2018-05-03 2019-11-07 The University Of British Columbia Cell encapsulation compositions and methods for immunocytochemistry
US20240122819A1 (en) * 2021-02-05 2024-04-18 Kao Corporation Hydrogel structure

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US4743545A (en) 1984-08-09 1988-05-10 Torobin Leonard B Hollow porous microspheres containing biocatalyst
US4303736A (en) 1979-07-20 1981-12-01 Leonard Torobin Hollow plastic microspheres
JPS608306A (ja) 1983-06-28 1985-01-17 Hitachi Chem Co Ltd 多孔性架橋重合体粒子の製造法
US5045569A (en) 1988-11-30 1991-09-03 Minnesota Mining And Manufacturing Company Hollow acrylate polymer microspheres
JPH05105729A (ja) * 1991-10-08 1993-04-27 Tokyo Keikaku:Kk 吸油性樹脂
US5508341A (en) 1993-07-08 1996-04-16 Regents Of The University Of California Organic aerogel microspheres and fabrication method therefor
US5712358A (en) * 1995-06-07 1998-01-27 Amcol International Corporation Process for producing an oil sorbent copolymer and the product thereof
JP4734685B2 (ja) * 1998-10-02 2011-07-27 昭和電工株式会社 多孔性共重合体粒子の製造方法
ATE266685T1 (de) 1998-10-02 2004-05-15 Showa Denko Kk Poröse copolymerpartikel, verfahren zu deren herstellung und deren verwendung
WO2002041987A2 (en) 2000-10-25 2002-05-30 Tufts University Polymeric microspheres
JP3888856B2 (ja) 2001-03-14 2007-03-07 積水化成品工業株式会社 多孔質樹脂微粒子およびそれを配合した外用剤
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Publication number Publication date
US9827318B2 (en) 2017-11-28
WO2013077981A1 (en) 2013-05-30
JP2014533756A (ja) 2014-12-15
CN104093754A (zh) 2014-10-08
EP2782941A1 (en) 2014-10-01
US20140309314A1 (en) 2014-10-16
CN104093754B (zh) 2017-06-23
EP2782941B1 (en) 2017-02-22

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