CN1039194C - 二甲胺四环素脉冲式一日一次释放系统 - Google Patents

二甲胺四环素脉冲式一日一次释放系统 Download PDF

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Publication number
CN1039194C
CN1039194C CN93101947A CN93101947A CN1039194C CN 1039194 C CN1039194 C CN 1039194C CN 93101947 A CN93101947 A CN 93101947A CN 93101947 A CN93101947 A CN 93101947A CN 1039194 C CN1039194 C CN 1039194C
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China
Prior art keywords
granule
coating
weight portions
soon
cellulose
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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CN93101947A
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English (en)
Chinese (zh)
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CN1078889A (zh
Inventor
尼丁V·谢斯
小约瑟夫J·瓦洛罗斯
基思A·埃尔威
马修雷Ｇ·加内森
凯伦Ｇ·穆尼
杰里B·约翰逊
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Wyeth Holdings LLC
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American Cyanamid Co
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Publication of CN1078889A publication Critical patent/CN1078889A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Treatment Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Laser Surgery Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Position Fixing By Use Of Radio Waves (AREA)
  • Physical Deposition Of Substances That Are Components Of Semiconductor Devices (AREA)
CN93101947A 1992-03-02 1993-02-25 二甲胺四环素脉冲式一日一次释放系统 Expired - Lifetime CN1039194C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/844,019 1992-03-02
US07/844,109 US5262173A (en) 1992-03-02 1992-03-02 Pulsatile once-a-day delivery systems for minocycline
US07/844,109 1992-03-02

Publications (2)

Publication Number Publication Date
CN1078889A CN1078889A (zh) 1993-12-01
CN1039194C true CN1039194C (zh) 1998-07-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN93101947A Expired - Lifetime CN1039194C (zh) 1992-03-02 1993-02-25 二甲胺四环素脉冲式一日一次释放系统

Country Status (24)

Country Link
US (2) US5262173A (enExample)
EP (1) EP0558913B1 (enExample)
JP (1) JPH069407A (enExample)
KR (1) KR100270491B1 (enExample)
CN (1) CN1039194C (enExample)
AT (1) ATE181504T1 (enExample)
AU (1) AU656841B2 (enExample)
CA (1) CA2090561C (enExample)
CZ (1) CZ283684B6 (enExample)
DE (1) DE69325402T2 (enExample)
DK (1) DK0558913T3 (enExample)
ES (1) ES2134221T3 (enExample)
FI (1) FI110163B (enExample)
GR (1) GR3031028T3 (enExample)
HU (1) HU219580B (enExample)
IL (1) IL104865A (enExample)
LV (1) LV12399B (enExample)
MX (1) MX9300998A (enExample)
NO (1) NO307170B1 (enExample)
NZ (1) NZ245951A (enExample)
PL (1) PL171609B1 (enExample)
SG (1) SG47785A1 (enExample)
TW (1) TW299235B (enExample)
ZA (1) ZA931444B (enExample)

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US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
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US20050137181A1 (en) * 1999-03-17 2005-06-23 Bonner Ernest L. Method for treatment of reactive arthritis or bursitis
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US7691831B2 (en) * 1999-03-17 2010-04-06 Ernest L. Bonner, Jr. Pharmaceutical combination and method for treatment of reactive arthritis or bursitis
US7884090B2 (en) * 1999-03-17 2011-02-08 Ernest L. Bonner, Jr. Compositions and methods for the treatment of arthritis
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US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
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US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
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AU2002227383B2 (en) 2000-10-30 2004-07-08 Euro-Celtique S.A. Controlled release hydrocodone formulations
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US6699315B2 (en) 2000-11-28 2004-03-02 Fmc Corporation Edible PGA coating composition
CA2447008A1 (en) * 2001-04-05 2002-10-24 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
CA2449731A1 (en) * 2001-06-07 2002-12-19 Tanabe Seiyaku Co., Ltd. Functional grain-containing preparations quickly disintegrated in the oral cavity
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
ES2530791T3 (es) 2002-12-20 2015-03-05 Hoffmann La Roche Formulación de ibandronato de altas dosis
CA2521885C (en) * 2003-04-07 2013-06-25 Shire Laboratories, Inc. Once daily formulations of tetracyclines
GB2414668B (en) * 2004-06-03 2009-07-29 Dexcel Ltd Tetracycline modified release delivery system
US8461187B2 (en) 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
US20060121112A1 (en) * 2004-12-08 2006-06-08 Elan Corporation, Plc Topiramate pharmaceutical composition
BRPI0608917A2 (pt) * 2005-04-12 2017-07-11 Elan Pharma Int Ltd Composição de liberação controlada de antibiótico, e, método para o tratamento de infecção bacteriana
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US9192615B2 (en) 2008-08-06 2015-11-24 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US20080318910A1 (en) * 2005-10-04 2008-12-25 Mistral Pharma, Inc. Controlled-Release Oral Dosage Form
US20070166273A1 (en) * 2006-01-19 2007-07-19 Krivulka Joseph J Skin treatment educational kit
PT103661B (pt) * 2007-02-23 2010-09-07 Hovione Farmaciencia S A Processo de preparação de minociclina base cristalina
US20080226734A1 (en) * 2007-03-16 2008-09-18 Elan Corporation Plc Combination of a narcotic and non-narcotic analgesic
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
RU2010119041A (ru) 2007-10-12 2011-11-20 Такеда Фармасьютикалз Норт Америка, Инк. (Us) Способы лечения нарушений желудочно-кишечного тракта, независимого от потребления пищи
CA2868990C (en) 2011-04-22 2018-08-14 Napo Pharmaceuticals, Inc. Pharmacologically optimized multimodal drug delivery system for nordihydroguiaretic acid (ndga)
EP2704698B1 (de) 2011-05-05 2019-10-02 Hennig Arzneimittel GmbH&Co. Kg Arzneiform zur gezielten freigabe von wirkstoffen
DE102011075354A1 (de) * 2011-05-05 2012-11-08 Hennig Arzneimittel Gmbh & Co. Kg Arzneiform zur gezielten Freigabe von Wirkstoffen
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
US11103517B2 (en) 2015-04-07 2021-08-31 Dr. Reddy's Laboratories Ltd. Pharmaceutical compositions for minocycline
CN108414466A (zh) * 2018-03-09 2018-08-17 浙江美华鼎昌医药科技有限公司 一种盐酸米诺环素缓释片体外溶出测定方法
MX2020011599A (es) * 2018-04-30 2021-01-15 Melinta Therapeutics Inc Métodos de tratamiento de infecciones bacterianas con minociclina.

Citations (2)

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US4250166A (en) * 1977-05-27 1981-02-10 Shionogi & Co., Ltd. Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds

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Patent Citations (2)

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US4250166A (en) * 1977-05-27 1981-02-10 Shionogi & Co., Ltd. Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin
US4837030A (en) * 1987-10-06 1989-06-06 American Cyanamid Company Novel controlled release formulations of tetracycline compounds

Also Published As

Publication number Publication date
AU656841B2 (en) 1995-02-16
FI930906L (fi) 1993-09-03
LV12399B (en) 2000-06-20
KR930019209A (ko) 1993-10-18
CN1078889A (zh) 1993-12-01
TW299235B (enExample) 1997-03-01
NO307170B1 (no) 2000-02-21
GR3031028T3 (en) 1999-12-31
NO930743D0 (no) 1993-03-01
PL297903A1 (en) 1993-11-15
FI930906A0 (fi) 1993-03-01
HU9300570D0 (en) 1993-05-28
EP0558913A1 (en) 1993-09-08
DK0558913T3 (da) 1999-12-13
SG47785A1 (en) 1998-04-17
HUT64851A (en) 1994-03-28
DE69325402D1 (de) 1999-07-29
ZA931444B (en) 1993-10-14
US5348748A (en) 1994-09-20
CA2090561C (en) 2004-10-05
NO930743L (no) 1993-09-03
US5262173A (en) 1993-11-16
ATE181504T1 (de) 1999-07-15
MX9300998A (es) 1993-09-01
HU219580B (hu) 2001-05-28
IL104865A (en) 1997-02-18
KR100270491B1 (ko) 2000-11-01
NZ245951A (en) 1994-06-27
HK1009930A1 (en) 1999-06-11
AU3384293A (en) 1993-09-09
CZ30093A3 (en) 1994-02-16
FI110163B (fi) 2002-12-13
EP0558913B1 (en) 1999-06-23
DE69325402T2 (de) 2000-02-17
IL104865A0 (en) 1993-06-10
CA2090561A1 (en) 1993-09-03
CZ283684B6 (cs) 1998-06-17
JPH069407A (ja) 1994-01-18
ES2134221T3 (es) 1999-10-01
LV12399A (lv) 1999-12-20
PL171609B1 (pl) 1997-05-30

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C06 Publication
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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
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GR01 Patent grant
C56 Change in the name or address of the patentee

Owner name: WYETH(AMERICAN HOME PRODUCTS) HOLDING CO., LTD.

Free format text: FORMER NAME OR ADDRESS: AMERICAN CYANAMID COMPANY

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Patentee after: Wyeth Holding Corp.

Patentee before: American Cyanamid Co.

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CX01 Expiry of patent term

Expiration termination date: 20130225

Granted publication date: 19980722