CN103735916A - Medicine for treating nephrotic syndrome and a preparation method thereof - Google Patents

Medicine for treating nephrotic syndrome and a preparation method thereof Download PDF

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CN103735916A
CN103735916A CN201410035670.7A CN201410035670A CN103735916A CN 103735916 A CN103735916 A CN 103735916A CN 201410035670 A CN201410035670 A CN 201410035670A CN 103735916 A CN103735916 A CN 103735916A
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rhizoma
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CN103735916B (en
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王莉
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Abstract

The invention discloses a medicine for treating nephrotic syndrome and a preparation method thereof. The medicine comprises the following components according to a certain weight ratio: eucommia bark, cassia twig, radix astragali, aconite, panax ginseng, radix pseudostellariae, prepared radix rehmanniae, leonurus heterophllus, rhizoma curculiginis and the like. The medicine of the invention has the efficacy of invigorating the kidney and strengthening yang, expelling wind and removing dampness and promoting urination and excreting dampness, and operates quickly and has good curative effect and no any toxic and side effect in treating nephritic syndrome.

Description

A kind of medicine for the treatment of the nephrotic syndrome and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of the nephrotic syndrome and preparation method thereof, belong to the field of Chinese medicines.
Background technology
The nephrotic syndrome is called for short nephropathy, is take glomerular basement membrane permeability as main disease, can be caused by Different types of etiopathogenises, and its clinical special disease is High-grade Proteinuria, hypoproteinemia, hypercholesterolemia and hydrosarca.Primary disease is comparatively common in kidney disease, and treatment not in time, often easily causes renal failure.At present, because Western medicine cannot effectively be treated nephropathy, and long-term taking Western medicine has more side effect, and therefore, people exist very large demand to the Chinese medicine of effective treatment nephropathy.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment nephropathy, thereby has completed the present invention.
Object of the present invention is just to provide a kind of composition of medicine that can effectively treat nephropathy.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention selects the Cortex Eucommiae, Ramulus Cinnamomi, the Radix Astragali, Radix Aconiti Lateralis Preparata, Radix Ginseng, Radix Pseudostellariae, Radix Rehmanniae Preparata, Herba Leonuri, Rhizoma Curculiginis, Pericarpium Citri Reticulatae, the Rhizoma Anemarrhenae, Radix Ophiopogonis, Radix Achyranthis Bidentatae, Fructus Mori, Herba Epimedii, Semen Cuscutae, Radix Et Rhizoma Rhei, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Colla Plastri Testudinis, Colla cornus cervi, Polyporus, Fructus Corni, Rhizoma Atractylodis, Radix Puerariae, Semen Plantaginis, Radix Dipsaci, Cortex Moutan medicine to combine, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat kidney palindromia.Wherein select the Cortex Eucommiae to be because its nature and flavor are sweet micro-pungent, temperature, enters liver, kidney channel, has invigorating the liver and kidney, bone and muscle strengthening, and antiabortive function, controls spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is wanted to fall, hypertension.Selecting Ramulus Cinnamomi is that temperature, enters bladder, the heart, lung meridian, has diaphoresis expelling pathogenic factors from muscles because of its property acrid-sweet flavor, and the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Select the Radix Astragali to be because its nature and flavor are sweet, tepor, enters lung, spleen channel, raw with the useful consolidating superficial resistance of defending, inducing diuresis to remove edema, and poison holding, the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle is not burst or is burst and hold back for a long time; Process by the function that has invigorating middle warmer benefit, control internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Selecting Radix Aconiti Lateralis Preparata is because of its property acrid-sweet flavor, and heat is poisonous, enter the heart, spleen, kidney channel, have recuperating depleted YANG to mend fire, the function of dispelling cold and removing dampness, control excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhea is fainted contrary, trusted subordinate's cold type of pain, the splenic diarrhea cold-dysentery, beriberi edema, children's's intermittent infantile convulsion, the contracture of anemofrigid-damp arthralgia , Wei lame, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses.Select Radix Ginseng to be because its nature and flavor are sweet micro-sweet, temperature, enters spleen, lung meridian, has strongly invigorating primordial QI, Gu de-, promote the production of body fluid, the function of calming the nerves, controls impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, stool lingering diarrhea, empty cough with asthma is short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quenches one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency are not multiple, the disease of all qi-blood-body fluid deficiencies.Selecting Radix Pseudostellariae is that tepor, enters the heart, spleen, lung three warps, has the function of tonifying the lung, spleen invigorating, controls cough due to deficiency of the lung because of its nature and flavor sweetness and bitterness, insufficiency of the spleen lack of appetite, and cardiopalmus order antiperspirant, spirit is tired.Select Radix Rehmanniae Preparata to be because its nature and flavor are sweet, tepor, enters liver, kidney channel, has YIN nourishing, and the function of enriching blood is controlled deficiency of YIN insufficiency of blood, waist knee flaccidity, and chronic cough hectic fever due to YIN-deficiency, seminal emission, metrorrhagia, menoxenia, quenches one's thirst, frequency of micturition, deafness, blurred vision.Select Herba Leonuri to be because its nature and flavor are arduous, cool, enter pericardium, Liver Channel, invigorate blood circulation, blood stasis dispelling, regulating menstruation, the function of the water that disappears, controls menoxenia, controls Lou difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Select Rhizoma Curculiginis to be because its nature and flavor are pungent, temperature, poisonous, enter kidney, Liver Channel, there is the kidney warming sun, the function of strengthening bone and muscle, controls sexual impotence cold sperm, urinary incontinence, metrorrhagia, trusted subordinate's cold type of pain, cold arthralgia of loins and legs, carbuncle, scrofula.Selecting Pericarpium Citri Reticulatae is that temperature, returns lung, spleen channel, has regulating qi-flowing for strengthening spleen because of its nature and flavor hardship, pungent, and the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Select the Rhizoma Anemarrhenae to be because its nature and flavor hardship is cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select be Radix Ophiopogonis because its property sweet and slightly bitter taste is cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, the relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid, controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, thirsty clearly, calentura Tianjin wound, dry mouth and throat, constipation.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, enter liver, kidney channel, dissipating blood stasis blood is used in life, and the function of subduing inflammation, controls gonorrhea, hematuria, amenorrhea , mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury, ripe in invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Select Fructus Mori to be because its nature and flavor are sweet, cold, enter liver, kidney channel, there is tonifying liver, kidney tonifying, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows the function of liquid, controls hepatic and renal YIN deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Selecting Herba Epimedii is that temperature, enters liver, kidney channel, has kidney invigorating and YANG supporting because of its property acrid-sweet flavor, and the function of expelling wind and removing dampness is controlled sexual impotence erectile problem, dribbling urination, and muscles and bones contraction is anxious, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, four feet are meciless.Select Semen Cuscutae to be because its property acrid-sweet flavor is flat, enter liver, kidney channel, have invigorating the liver and kidney, beneficial marrow, the function of improving eyesight, controls soreness of waist and knee joint, and seminal emission, quenches one's thirst, dripping urination, order is dark.Select Radix Et Rhizoma Rhei to be because its nature and flavor hardship, cold enters stomach, large intestine, liver footpath, have the poison of purging heat, removing mass is stagnant, the function of clots absorbing blood, controls excess-heat constipation, and delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi , lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Select Caulis Bambusae In Taenia to be because its nature and flavor are sweet, cool, enter stomach, gallbladder meridian, have heat clearing away, removing heat from blood, reduces phlegm, and the function of emesis is controlled dysphoria with smothery sensation vomiting, singultus, and expectorant heat syndrome cough is breathed heavily, spit blood, and epistaxis, metrorrhagia, malignant histocytosis, fetal movement , Jing Epilepsy.Selecting the Rhizoma Atractylodis Macrocephalae is because its property bitter but sweet flavor, and temperature, enters spleen, stomach warp, has spleen reinforcing, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.Select Colla Plastri Testudinis to be because its property sweet-salty is flat, have YIN nourishing, enrich blood, the function of hemostasis, controls deficiency of YIN anemia, and consumptive fever hectic fever due to YIN-deficiency is spitted blood, epistaxis, dysphoria with smothery sensation palpitation with fear, lumbago due to renal deficiency, flaccidity of feet and knees, metrorrhagia, leukorrhagia.Selecting Colla cornus cervi is that temperature, enters liver, kidney channel because of its property sweet-salty, enriches blood, and the function of benefit essence, controls deficiency of kidney-QI, asthenia weakness and emaciation, lumbago, carbuncle of yin nature, impotence in male, spermatorrhea, uterus cold caused by deficiency, metrorrhagia, leukorrhagia.Select Polyporus to be because its property slightly sweet flavor is flat, enter spleen, kidney, urinary bladder channel, have the function of diuresis eliminating dampness by diuresis, control dysuria, edema distension, beriberi, has loose bowels, pouring, turbid, leukorrhagia.Selecting Fructus Corni is that tepor, enters liver, kidney channel, has invigorating the liver and kidney because of its nature and flavor acid, and arresting seminal emission gas is Gu the function of collapse is controlled soreness of waist and knee joint, dizzy, tinnitus, and sexual impotence, seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart shakes scattered pulse.Select Rhizoma Atractylodis to be because its nature and flavor are arduous, temperature, enters spleen, stomach warp, has spleen invigorating, dampness, and resolving depression, wards off dirty function, control the wet tired spleen of containing, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Select Radix Puerariae to be because its nature and flavor are sweet pungent, flat, enter spleen, stomach warp, there is yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is quenched the thirst, cures the wound cold, warm, headache, stiffness of the nape, dysphoria with smothery sensation disappears and drinks, has loose bowels, dysentery, abnormal pigmentary deposit on the skin is examined not saturating, hypertension, angina pectoris, deafness.Select Semen Plantaginis to be because its nature and flavor are sweet, cold, enter kidney, urinary bladder channel, there is diuretic, heat clearing away, improving eyesight, the function of eliminating the phlegm, controls urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.Selecting Radix Dipsaci is that tepor, enters liver, kidney channel, has invigorating the liver and kidney because of its nature and flavor toil, reuniting the fractured tendons and bones, and the function of blood circulation regulating, controls aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer is swollen.Select Cortex Moutan to be because its nature and flavor are arduous, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, sends out speckle , Jing Epilepsy, and tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Cortex Eucommiae 5-15 gram of Ramulus Cinnamomi 5-15 gram of Radix Astragali 10-20 gram
Radix Aconiti Lateralis Preparata 5-15 gram of Radix Ginseng 5-15 gram of Radix Pseudostellariae 5-15 gram
Radix Rehmanniae Preparata 5-15 gram of Herba Leonuri 5-15 gram of Rhizoma Curculiginis 5-15 gram
Pericarpium Citri Reticulatae 15-25 gram Rhizoma Anemarrhenae 15-25 gram Radix Ophiopogonis 15-25 gram
Radix Achyranthis Bidentatae 10-20 gram of Fructus Mori 10-20 gram of Herba Epimedii 10-20 gram
Semen Cuscutae 10-20 gram of Radix Et Rhizoma Rhei 10-20 gram of Caulis Bambusae In Taenia 10-20 gram
Rhizoma Atractylodis Macrocephalae 15-25 gram of Colla Plastri Testudinis 15-25 gram of Colla cornus cervi 15-25 gram
15-25 gram of Rhizoma Atractylodis 10-20 gram of the Polyporus 15-25 Keshan Fructus Evodiae
Radix Puerariae 10-20 gram of Semen Plantaginis 10-20 gram of Radix Dipsaci 10-20 gram
Cortex Moutan 10-20 gram
Preferable amount is
15 grams of 10 grams of Radixs Astragali of 10 grams of Ramulus Cinnamomi of the Cortex Eucommiae
10 grams of 10 grams of Radix Pseudostellariaes of 10 grams of Radix Ginsengs of Radix Aconiti Lateralis Preparata
10 grams of 10 grams of Rhizoma Curculiginises of 10 grams of Herba Leonuris of Radix Rehmanniae Preparata
20 grams of 20 grams of Rhizoma Anemarrhenaes of Pericarpium Citri Reticulatae 20 grams of Radix Ophiopogonis
15 grams of 15 grams of Herba Epimedii of 15 grams of Fructus Moris of Radix Achyranthis Bidentatae
15 grams of 15 grams of Caulis Bambusae In Taenia of 15 grams of Radix Et Rhizoma Rhei of Semen Cuscutae
20 grams of 20 grams of Colla cornus cervis of 20 grams of Colla Plastri Testudinis of the Rhizoma Atractylodis Macrocephalae
15 grams of 20 grams of Rhizoma Atractylodis of the Polyporus 20 Keshan Fructus Evodiae
15 grams of 15 grams of Radix Dipsacis of 15 grams of Semen Plantaginiss of Radix Puerariae
15 grams of Cortex Moutans
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, the Cortex Eucommiae: remove rough bark, clean, run through, dice or strand, dry;
2, Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;
3, the Radix Astragali: choose clean impurity, remove residual root head and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
4, Radix Aconiti Lateralis Preparata: be soaked in water, pull out, section, dries;
5, Radix Ginseng: except removing LU, cutting;
6, Radix Pseudostellariae: extract fibrous root, dry;
7, Radix Rehmanniae Preparata: get crude drug, steam to surperficial corvinus, take out, shines when dry to eighty per cant, section, is dried;
8, Herba Leonuri: choose decontamination, clean, run through, cutting, dries;
9, Rhizoma Curculiginis: get clean Rhizoma Curculiginis yellow wine and mix thoroughly, after running through, put pot interior micro-stir-fry to dry, take out, dry, 100 jin of every Rhizoma Curculiginises, with yellow wine 10-20 jin;
10, Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, softens, and shredding, dries or cold drying, sieve dedust bits;
11, the Rhizoma Anemarrhenae: choose clean impurity, water hits to be washed, and pulls out, softens, and section is dried;
12, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, pump the heart after running through, then clean and dry;
13, Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
14, Fructus Mori: wash, choose decontamination, extract long handle, dry;
15, Herba Epimedii: choose clean impurity, destemming, shredding, sieve removes chip;
16, Semen Cuscutae: cross square-bottomed bamboo basket and remove impurity, clean, dry;
17, Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;
18, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off ash bits, be kneaded into little group or cutting;
19, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
20, Colla Plastri Testudinis: get the clean Carapax et Plastrum Testudinis floating after bubble, put decocting in pot and for several times, decoct to colloid most, go dregs, by repeatedly fried glue, filter and merge, add a little alum powder, standing, the glue of leaching clarification, concentrated or add appropriate yellow wine, crystal sugar to be to thick paste shape with slow fire, in impouring gel groove, make to take out after its condensation, be cut into small pieces, dry in the shade;
21, Colla cornus cervi: get crude drug, remove impurity, the used time smashs to pieces or levigation;
22, Polyporus: clean silt particle, soften section, dry;
23, Fructus Corni: clean, except removal core and impurity, dry;
24, Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;
25, Radix Puerariae: choose decontamination, clean, be soaked in water, pull out, run through, section, dries in time;
26, Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
27, Radix Dipsaci: clean silt, remove retained root head, run through rear section and dry, sieve anti-dandruff;
28, Cortex Moutan: choose decontamination, remove core, clean, run through, section, dries.
Two, preparation
1, the Cortex Eucommiae of described weight, Ramulus Cinnamomi, the Radix Astragali, Radix Aconiti Lateralis Preparata, Radix Ginseng, Radix Pseudostellariae, Radix Rehmanniae Preparata, Herba Leonuri, Rhizoma Curculiginis, Pericarpium Citri Reticulatae, the Rhizoma Anemarrhenae, Radix Ophiopogonis, Radix Achyranthis Bidentatae, Fructus Mori, Herba Epimedii, Semen Cuscutae, Radix Et Rhizoma Rhei, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Polyporus, Fructus Corni, Rhizoma Atractylodis, Radix Puerariae, Semen Plantaginis, Radix Dipsaci, Cortex Moutan medicine are decocted with water to secondary, add for the first time 6 times of amounts of water, intense fire decocts boiling 30 minutes, use again slow fire boiling 20 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time.
2, will filter for the first time rear medicinal residues and add 4 times of amounts of water, decoct boiling, then use slow fire boiling 40 minutes, filter to obtain decoction liquor for the second time.
3, twice decoction liquor mixed, add while hot the Colla Plastri Testudinis of described weight and Colla cornus cervi to be dissolved in decoction medicinal liquid, stir, be divided into 4 doses and take.
Medicine of the present invention has kidney invigorating and YANG supporting, expelling wind and removing dampness, and the effect of diuresis eliminating dampness by diuresis, treatment nephropathy instant effect, short treating period, do not recur.
By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.4kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit activities, diet are normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 187 examples for medical treatment.
2, diagnostic criteria
Clinical manifestation
(1) anasarca: start to see eyelid and face, spread all over gradually whole body, severe patient can have thoracic cavity, seroperitoneum and scrotum, penis, labia edema;
(2) blood pressure is normal or increase;
(3) can there be oliguria or hematuria.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, each serving with 1 dose, every day early, respectively take 1 evening, within 10 days, is a course for the treatment of, takes continuously 6 courses for the treatment of.
4, efficacy assessment standard
Effective: the nephrotic syndrome is eliminated, observe after half a year without recurrence;
Take a turn for the better: nephropathy symptom is clearly better;
Invalid: symptom, without improvement, does not reach improvement standard person.
5, therapeutic outcome
Figure 112621DEST_PATH_IMAGE002
In above-mentioned treatment, by Drug therapy nephrotic's 187 examples of the present invention, effective 180 examples of result, obvious effective rate is 96.26%, 5 examples that take a turn for the better, and improvement rate is 2.67%, invalid 2 examples, total effective rate is 98.93%.

Claims (3)

1. a medicine for the treatment of the nephrotic syndrome, is characterized in that: it is to be made by the crude drug in following weight range:
Cortex Eucommiae 5-15 gram of Ramulus Cinnamomi 5-15 gram of Radix Astragali 10-20 gram
Radix Aconiti Lateralis Preparata 5-15 gram of Radix Ginseng 5-15 gram of Radix Pseudostellariae 5-15 gram
Radix Rehmanniae Preparata 5-15 gram of Herba Leonuri 5-15 gram of Rhizoma Curculiginis 5-15 gram
Pericarpium Citri Reticulatae 15-25 gram Rhizoma Anemarrhenae 15-25 gram Radix Ophiopogonis 15-25 gram
Radix Achyranthis Bidentatae 10-20 gram of Fructus Mori 10-20 gram of Herba Epimedii 10-20 gram
Semen Cuscutae 10-20 gram of Radix Et Rhizoma Rhei 10-20 gram of Caulis Bambusae In Taenia 10-20 gram
Rhizoma Atractylodis Macrocephalae 15-25 gram of Colla Plastri Testudinis 15-25 gram of Colla cornus cervi 15-25 gram
15-25 gram of Rhizoma Atractylodis 10-20 gram of the Polyporus 15-25 Keshan Fructus Evodiae
Radix Puerariae 10-20 gram of Semen Plantaginis 10-20 gram of Radix Dipsaci 10-20 gram
Cortex Moutan 10-20 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
15 grams of 10 grams of Radixs Astragali of 10 grams of Ramulus Cinnamomi of the Cortex Eucommiae
10 grams of 10 grams of Radix Pseudostellariaes of 10 grams of Radix Ginsengs of Radix Aconiti Lateralis Preparata
10 grams of 10 grams of Rhizoma Curculiginises of 10 grams of Herba Leonuris of Radix Rehmanniae Preparata
20 grams of 20 grams of Rhizoma Anemarrhenaes of Pericarpium Citri Reticulatae 20 grams of Radix Ophiopogonis
15 grams of 15 grams of Herba Epimedii of 15 grams of Fructus Moris of Radix Achyranthis Bidentatae
15 grams of 15 grams of Caulis Bambusae In Taenia of 15 grams of Radix Et Rhizoma Rhei of Semen Cuscutae
20 grams of 20 grams of Colla cornus cervis of 20 grams of Colla Plastri Testudinis of the Rhizoma Atractylodis Macrocephalae
15 grams of 20 grams of Rhizoma Atractylodis of the Polyporus 20 Keshan Fructus Evodiae
15 grams of 15 grams of Radix Dipsacis of 15 grams of Semen Plantaginiss of Radix Puerariae
15 grams of Cortex Moutans.
3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Cortex Eucommiae: remove rough bark, clean, run through, dice or strand, dry;
(2) Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;
(3) Radix Astragali: choose clean impurity, remove residual root head and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
(4) Radix Aconiti Lateralis Preparata: be soaked in water, pull out, section, dries;
(5) Radix Ginseng: except removing LU, cutting;
(6) Radix Pseudostellariae: extract fibrous root, dry;
(7) Radix Rehmanniae Preparata: get crude drug, steam to surperficial corvinus, take out, shines when dry to eighty per cant, section, is dried;
(8) Herba Leonuri: choose decontamination, clean, run through, cutting, dries;
(9) Rhizoma Curculiginis: get clean Rhizoma Curculiginis yellow wine and mix thoroughly, after running through, put pot interior micro-stir-fry to dry, take out, dry, 100 jin of every Rhizoma Curculiginises, with yellow wine 10-20 jin;
(10) Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, softens, and shredding, dries or cold drying, sieve dedust bits;
(11) Rhizoma Anemarrhenae: choose clean impurity, water hits to be washed, and pulls out, softens, and section is dried;
(12) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, pump the heart after running through, then clean and dry;
(13) Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
(14) Fructus Mori: wash, choose decontamination, extract long handle, dry;
(15) Herba Epimedii: choose clean impurity, destemming, shredding, sieve removes chip;
(16) Semen Cuscutae: cross square-bottomed bamboo basket and remove impurity, clean, dry;
(17) Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;
(18) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off ash bits, be kneaded into little group or cutting;
(19) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
(20) Colla Plastri Testudinis: get the clean Carapax et Plastrum Testudinis floating after bubble, put decocting in pot and for several times, decoct to colloid most, go dregs, by repeatedly fried glue, filter and merge, add a little alum powder, standing, the glue of leaching clarification, concentrated or add appropriate yellow wine, crystal sugar to be to thick paste shape with slow fire, in impouring gel groove, make to take out after its condensation, be cut into small pieces, dry in the shade;
(21) Colla cornus cervi: get crude drug, remove impurity, the used time smashs to pieces or levigation;
(22) Polyporus: clean silt particle, soften section, dry;
(23) Fructus Corni: clean, except removal core and impurity, dry;
(24) Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;
(25) Radix Puerariae: choose decontamination, clean, be soaked in water, pull out, run through, section, dries in time;
(26) Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
(27) Radix Dipsaci: clean silt, remove retained root head, run through rear section and dry, sieve anti-dandruff;
(28) Cortex Moutan: choose decontamination, remove core, clean, run through, section, dries;
(2) preparation
(1) Cortex Eucommiae of described weight, Ramulus Cinnamomi, the Radix Astragali, Radix Aconiti Lateralis Preparata, Radix Ginseng, Radix Pseudostellariae, Radix Rehmanniae Preparata, Herba Leonuri, Rhizoma Curculiginis, Pericarpium Citri Reticulatae, the Rhizoma Anemarrhenae, Radix Ophiopogonis, Radix Achyranthis Bidentatae, Fructus Mori, Herba Epimedii, Semen Cuscutae, Radix Et Rhizoma Rhei, Caulis Bambusae In Taenia, the Rhizoma Atractylodis Macrocephalae, Polyporus, Fructus Corni, Rhizoma Atractylodis, Radix Puerariae, Semen Plantaginis, Radix Dipsaci, Cortex Moutan medicine are decocted with water to secondary, add for the first time 6 times of amounts of water, intense fire decocts boiling 30 minutes, use again slow fire boiling 20 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time;
(2) will filter for the first time rear medicinal residues and add 4 times of amounts of water, decoct boiling, then use slow fire boiling 40 minutes, filter to obtain decoction liquor for the second time;
(3) twice decoction liquor mixed, add while hot the Colla Plastri Testudinis of described weight and Colla cornus cervi to be dissolved in decoction medicinal liquid, stir, be divided into 4 doses and take.
CN201410035670.7A 2014-01-26 2014-01-26 A kind of medicine for the treatment of the nephrotic syndrome and preparation method thereof Expired - Fee Related CN103735916B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104288543A (en) * 2014-08-19 2015-01-21 肖仕琼 Frequently-drank tea-substituting traditional Chinese medicine preparation for treating kidney diseases
CN105148107A (en) * 2015-08-21 2015-12-16 王莉 Medicine for treating nephrosis and preparation method of medicine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1253783A (en) * 1998-11-16 2000-05-24 吴学栋 Kidney-supplementing yang-invigorating channels-freeing dampness-dispelling medicated liquor
CN1861163A (en) * 2006-04-08 2006-11-15 兰州和盛堂制药有限公司 Traditional Chinese medicine composition for treating kidney-yang deficiency and deficiency of vital energy and blood, its prepn. process
CN102100845A (en) * 2011-01-25 2011-06-22 李文杰 Medicament for treating deficiency of kidney, frequent micturition, urgent urination and prostatitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1253783A (en) * 1998-11-16 2000-05-24 吴学栋 Kidney-supplementing yang-invigorating channels-freeing dampness-dispelling medicated liquor
CN1861163A (en) * 2006-04-08 2006-11-15 兰州和盛堂制药有限公司 Traditional Chinese medicine composition for treating kidney-yang deficiency and deficiency of vital energy and blood, its prepn. process
CN102100845A (en) * 2011-01-25 2011-06-22 李文杰 Medicament for treating deficiency of kidney, frequent micturition, urgent urination and prostatitis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104288543A (en) * 2014-08-19 2015-01-21 肖仕琼 Frequently-drank tea-substituting traditional Chinese medicine preparation for treating kidney diseases
CN105148107A (en) * 2015-08-21 2015-12-16 王莉 Medicine for treating nephrosis and preparation method of medicine

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