CN103721223A - Medicine for treating functional uterine bleeding and preparation method thereof - Google Patents
Medicine for treating functional uterine bleeding and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating functional uterine bleeding and a preparation method thereof. The medicine is mainly prepared from concha ostreae, fluorite violet quartz, herba ecliptae, turtle shell, folium mori, cockscombs, herba agrimoniae and other medicines according to a certain weight proportion. The medicine has the functions of cooling blood, stopping bleeding, dispersing blood stasis, relieving pain, calming the adverse-rising energy and warming the uterus, is high in efficiency when being used for treating functional uterine bleeding, and good in curative effect, and avoids relapse.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of dysfunctional uterine hemorrhage and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Dysfunctional uterine bleeding is called for short dysfunctional uterine hemorrhage or anovulatory dysfunctional uterine hemorrhage, is caused, rather than caused by gestation, endometrial tumors, infection or hematopathy etc. by neuroendocrine imbalance.Often betide adolescence, be anovulation type dysfunctional uterine hemorrhage, also claim pubertal dysfunctional uterine bleeding.At present, because Western medicine cannot effectively be treated dysfunctional uterine hemorrhage, and long-term taking Western medicine has more side effect, and therefore, people exist very large demand to the Chinese medicine of effective treatment dysfunctional uterine hemorrhage.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment dysfunctional uterine hemorrhage, thereby has completed the present invention.
Object of the present invention is just to provide a kind of composition of medicine that can effectively treat dysfunctional uterine hemorrhage.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention is to select Concha Ostreae, Fluoritum, Herba Ecliptae, Carapax Trionycis, Folium Mori, Flos Celosiae Cristatae, Herba Agrimoniae, Endoconcha Sepiae, Radix Patriniae heterophyllae, Exocarpium Litchi, Herba Cirsii, the Radix Pulsatillae, Fructus Mori, Os Draconis, Radix Notoginseng, Radix Ginseng Rubra, Radix Rumicis Japonici, Herba Chenopodii Hybridi, Herba Capsellae, Semen Ziziphi Spinosae, Flos Chrysanthemi Indici, Nodus Nelumbinis Rhizomatis, Terra Flava Usta, Semen Benincasae, Rhizoma Zingiberis Recens, Fructus Lycii, Rhizoma Paridis, Fructus Rosae Laevigatae, Cortex Ailanthi, Fructus Jujubae, Herba Pyrolae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Herba Schizonepetae, Colla cornus cervi, Semen Cuscutae, Radix Codonopsis medicine combines, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat the recurrence of dysfunctional uterine hemorrhage.Wherein select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select Fluoritum to be because its nature and flavor are sweet, temperature, enters the heart, Liver Channel, has relieving palpitation, calm the nerves, and lowering the adverse flow of QI, the function in warm uterus, controls asthenia palpitation with fear, cough with dyspnea, women's sea of blood deficiency and coldness is infertile.Select Herba Ecliptae to be because its nature and flavor picric acid is cool, enter liver, kidney channel, have removing heat from blood, hemostasis, the kidney invigorating, the function of tonifying YIN, controls haematemesis, hemoptysis, epistaxis, hematuria, has blood in stool, dysentery, knife injury is hemorrhage, early whitening of beard and hair, diphtheria, stranguria with turbid discharge, dysentery, pudendum pruritus due to damp pathogen.Select Carapax Trionycis to be because its nature and flavor are salty, flat, enter liver, spleen channel, there is replenishing YIN and removing heat, suppressing the hyperactive liver to relieve the wind syndrome, the function of hard masses softening and resolving, controls consumptive fever hectic fever due to YIN-deficiency, stirring of wind due to deficiency of YIN, malaria with general debility malaria with splenomegaly ， mass in the abdomen mass beside the umbilicus, amenorrhea menometrorrhagia, little Jing Epilepsy.Select Folium Mori to be because its property bitter but sweet flavor is cold, enter lung, Liver Channel, have expelling wind and clearing away heat, the function of cooling blood for improving eyesight, dispelling the wind and dampness pathogens heating, headache, conjunctival congestion, thirsty, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.Select Flos Celosiae Cristatae to be because it is because its nature and flavor nature and flavor are sweet, cool, enter liver channel of foot-Jueyin, have removing heat from blood, the function of hemostasis, controls anal fistula hematochezia, and red white dysentery is spitted blood, hemoptysis, stranguria with blood, women's metrorrhagia, leucorrhea with red and white discharge.Select Herba Agrimoniae to be because its nature and flavor toil is flat, enter lung, liver, spleen channel, have hemostasis, the function of stomach invigorating, controls spitting of blood, spits blood, and hematuria, has blood in stool, dysentery, and bleeding not during menses, impairment caused by overstrain takes off power, carbuncle, traumatic injury, wound hemorrhage.Select Endoconcha Sepiae to be because its nature and flavor are salty, tepor, enters liver, kidney channel, has dehumidifying, antacid, and hemostasis, the function of sore, the acid regurgitation that treats for stomachache, tells, nosebleed, hematemesis, has blood in stool, bleeding not during menses, amenorrhea due to blood depletion, Fu Tong mass in the abdomen, intermittent fever of deficiency type dysentery, the rotten skin ulcer of the erosion of the vulva.Select Radix Patriniae heterophyllae to be because its nature and flavor are pungent, warm in nature, enter the heart, liver two warps, control pyrexial malaria, women's metrorrhagia, leucorrhea with red and white discharge, traumatic injury.Select Exocarpium Litchi to be because it controls dysentery, metrorrhagia, eczema.Select Herba Cirsii to be because its nature and flavor are pungent, temperature, enters spleen, stomach two warps, has warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, and rapid digestion of food, the function of parasite killing, controls vomiting and diarrhoea, trusted subordinate's distending pain, furuncle toxic swelling skin ulcer, poisonous insect flood dragon wound.Select the Radix Pulsatillae to be because its nature and flavor hardship is cold, enter large intestine, liver, stomach warp, have clearing away heat and cooling blood, the function of removing toxic substances, controls toxic-heat and blood stasis, pyrexial malaria cold and heat, epistaxis, internal hemorrhoid with bleeding.Select Fructus Mori to be because its nature and flavor are sweet, cold, enter liver, kidney channel, there is tonifying liver, kidney tonifying, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows the function of liquid, controls hepatic and renal YIN deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Select Os Draconis to be because its property sweet-puckery flavor is flat, be included into the heart, liver, kidney, large intestine channel, have tranquillizing the mind by relieving convulsion, the function of arresting sweating controlling nocturnal emission with astringent drugs, controls frightened Epilepsy demented, and palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating.Selecting Radix Notoginseng is that temperature, enters liver, stomach, large intestine channel, has hemostasis because of its property sweet and slightly bitter taste, dissipating blood stasis, and detumescence, the function of analgesic therapy, controls haematemesis, hemoptysis, epistaxis, has blood in stool, dysentery, metrorrhagia, mass in the abdomen, puerperal blood faints, retention of lochia, falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain.Selecting Radix Ginseng Rubra is that temperature, returns spleen, lung, heart channel, has strongly invigorating primordial QI because of sweet, the micro-hardship of its nature and flavor, and multiple arteries and veins is admittedly de-, and the function of nourishing qi to stop, controls weak body and prostration, cold extremities faint pulse, QI failing to control blood, metrostaxis, heart failure, cardiogenic shock.Select Radix Rumicis Japonici to be because its nature and flavor hardship is cold, slightly poisonous, enter meridian of Hand-SHAO YIN, have heat clearing away, relieving constipation, diuretic, hemostasis, the function of parasite killing, controls constipation due to dry stool, stranguria with turbid discharge, jaundice, spits blood, hemorrhoidal hamorrhage, dysfunctional uterine hemorrhage, tinea alba, scabies, carbuncle, traumatic injury.Select Herba Chenopodii Hybridi to be because its nature and flavor are sweet, flat, there is hemostasis, the function of invigorating blood circulation, controls menoxenia, metrorrhagia, spitting of blood, epistaxis, hematuria, sore and toxic.Select Herba Capsellae to be because its nature and flavor are sweet, flat, enter meridian of Foot-JUE YIN, have and spleen, diuretic, hemostasis, the function of improving eyesight, controls dysentery, edema, gonorrhea, chyluria, spits blood, has blood in stool, metrorrhagia, menorrhagia, conjunctival congestion and pain of eye.Select Semen Ziziphi Spinosae to be because its nature and flavor are sweet, flat, enter the heart, spleen, liver, gallbladder meridian, there is nourishing the liver, mind calming, calms the nerves, and the function of arresting sweating, controls restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.Select Flos Chrysanthemi Indici to be because its nature and flavor toil is cool, enter lung, Liver Channel, have wind and heat dispersing, the function of subduing swelling and detoxicating, controls anemopyretic cold, pneumonia, diphtheria, gastroenteritis, hypertension, furuncle, carbuncle, aphtha, erysipelas, eczema, epidemic blisters.Select Nodus Nelumbinis Rhizomatis to be because its property sweet-puckery flavor is flat, few the moon of starting with, foot sun is bright, and JUE YIN meridian, has hemostasis, and the function of dissipating blood stasis, controls hemoptysis, spits blood, epistaxis, hematuria, has blood in stool, dysentery, metrorrhagia.Select Terra Flava Usta to be because its nature and flavor are pungent, temperature, enters spleen, stomach warp, has warming middle-JIAO dampness, the function of preventing or arresting vomiting hemostasis, stopping vomiting is told regurgitation, stomachache is had loose bowels, haematemesis, epistaxis, have blood in stool, hematuria, forepart pregnant women malignant histocytosis, bleeding not during menses, carbuncle ulcer.Select Semen Benincasae to be because its property slightly sweet flavor is cool, enter lung, intestine and small intestine, urinary bladder channel, have diuretic, expectorant, heat clearing away, the function of removing toxic substances, harnesses the river swollen, distension, beriberi, gonorrhea, expectorant is shouted, cough with asthma, summer-heat unhappiness, quenches one's thirst, dysentery, carbuncle, anal fistula, and separate ichthyotoxin, alcoholism.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enters lung, stomach, spleen channel, deliver, and cold expelling, preventing or arresting vomiting, opens the function of expectorant, the wind and cold that cures cold, vomiting, phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Fructus Lycii to be because its nature and flavor are sweet, flat, there is nourishing kidney, lung moistening, tonifying liver, the function of improving eyesight, controls hepatic and renal YIN deficiency, and soreness of the waist and knees is had a dizzy spell, the many tear of blurred vision, cough due to consumptive disease, quenches one's thirst, and loses clear.Select Rhizoma Paridis to be because its nature and flavor toil is cold, poisonous, enter the heart, Liver Channel, have heat-clearing and toxic substances removing, antiasthmatic-antitussive, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls carbuncle, furuncle, scrofula, sore throat, chronic tracheitis, infantile convulsion is twitched, snake bite and insect sting.Select Fructus Rosae Laevigatae to be because its nature and flavor are sour and astringent, flat, enter kidney, bladder, large intestine channel, there is reinforcing the kidney and controlling nocturnal emission, the function of reducing urination and antidiarrheal, controls spermatorrhea, the enuresis, frequent micturition, insufficiency of the spleen dysentery, the deficiency of the lung is breathed with cough, spontaneous sweating, bone leaks leukorrhagia.Select Cortex Ailanthi to be because its nature and flavor hardship, puckery is cold, return large intestine, stomach, Liver Channel, have heat clearing and damp drying, the function of astringent therapy leukorrhagia stopping, antidiarrheal, hemostasis, controls leucorrhea with red and white discharge, and damp-heat dysentery rushes down chronic dysentery outward, have blood in stool, and metrorrhagia.Select Fructus Jujubae to be because its nature and flavor are sweet, temperature, enters spleen, stomach warp, has spleen reinforcing stomach function regulating, and supplementing QI for promoting the production of body fluid adjusts battalion to defend, and separates the function of poison of drug, controls insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid deficiency, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Selecting Herba Pyrolae is that temperature, enters liver, kidney two warps, has tonify deficiency because of its nature and flavor sweetness and bitterness, kidney tonifying, and expelling wind and removing dampness, the function of promoting blood flow to regulate menstruation, controls weak cough, over-strained hemoptysis, rheumatic arthritis, metrorrhagia, leucorrhea, traumatic hemorrhage.Select Radix Angelicae Pubescentis to be because its nature and flavor are arduous, temperature, enters kidney, urinary bladder channel, dispels the wind, and victory is wet, cold expelling, and the function of pain relieving, controls anemofrigid-damp arthralgia, waist urushic acid pain, trick spasm and pain, chronic tracheitis, headache, toothache.Selecting Fructus Schisandrae Chinensis is that temperature, enters lung, kidney channel, astringes the lung because of its nature and flavor acid, and nourishing kidney, promotes the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Select Herba Schizonepetae to be because its nature and flavor are pungent, temperature, enters lung, Liver Channel, delivers, dispel the wind, and the function for the treatment of blood disorders, parch to black hemostasis, the heating that cures cold, headache, laryngopharynx swelling and pain, apoplexy locked mouth, spits blood, and epistaxis, has blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Selecting Colla cornus cervi is that temperature, enters liver, kidney channel because of its property sweet-salty, enriches blood, and the function of benefit essence, controls deficiency of kidney-QI, asthenia weakness and emaciation, lumbago, carbuncle of yin nature, impotence in male, spermatorrhea, uterus cold caused by deficiency, metrorrhagia, leukorrhagia.Select Semen Cuscutae to be because its property acrid-sweet flavor is flat, enter liver, kidney channel, have invigorating the liver and kidney, beneficial marrow, the function of improving eyesight, controls soreness of waist and knee joint, and seminal emission, quenches one's thirst, dripping urination, order is dark.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, and fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Concha Ostreae 15-25 gram of Fluoritum 15-25 gram of Herba Ecliptae 15-25 gram
Carapax Trionycis 10-20 gram of Folium Mori 10-20 gram of Flos Celosiae Cristatae 10-20 gram
Herba Agrimoniae 10-20 gram of Endoconcha Sepiae 10-20 gram of Radix Patriniae heterophyllae 10-20 gram
Exocarpium Litchi 10-20 gram of Herba Cirsii 5-15 gram of Radix Pulsatillae 5-15 gram
5-15 gram of Radix Notoginseng 5-15 gram of Fructus Mori 5-15 cron bone
Radix Ginseng Rubra 5-15 gram of Radix Rumicis Japonici 5-15 gram of Herba Chenopodii Hybridi 5-15 gram
Herba Capsellae 15-25 gram of Semen Ziziphi Spinosae 15-25 gram of Flos Chrysanthemi Indici 15-25 gram
Nodus Nelumbinis Rhizomatis 15-25 gram of Terra Flava Usta 15-25 gram of Semen Benincasae 15-25 gram
Rhizoma Zingiberis Recens 15-25 gram of Fructus Lycii 15-25 gram of Rhizoma Paridis 15-25 gram
Fructus Rosae Laevigatae 10-20 gram of Cortex Ailanthi 10-20 gram of Fructus Jujubae 10-20 gram
Herba Pyrolae 15-25 gram of Radix Angelicae Pubescentis 15-25 gram of Fructus Schisandrae Chinensis 15-25 gram
Herba Schizonepetae 5-15 gram of Colla cornus cervi 5-15 gram of Semen Cuscutae 5-15 gram
Radix Codonopsis 10-20 gram
Preferable amount is
20 grams of 20 grams of Herba Ecliptaes of 20 grams of Fluoritum of Concha Ostreae
15 grams of 15 grams of Flos Celosiae Cristataes of 15 grams of Folium Mori of Carapax Trionycis
15 grams of 15 grams of Radix Patriniae heterophyllaes of 15 grams of Endoconcha Sepiaes of Herba Agrimoniae
10 grams of 10 grams of Radix Pulsatillaes of 15 grams of Herba Cirsiis of Exocarpium Litchi
10 grams of 10 grams of Radix Notoginseng of Fructus Mori 10 cron bone
10 grams of 10 grams of Herba Chenopodii Hybridis of 10 grams of Radix Rumicis Japonicis of Radix Ginseng Rubra
20 grams of 20 grams of Flos Chrysanthemi Indicis of 20 grams of Semen Ziziphi Spinosaes of Herba Capsellae
20 grams of 20 grams of Semen Benincasaes of 20 grams of Terra Flava Ustas of Nodus Nelumbinis Rhizomatis
20 grams of 20 grams of Rhizoma Paridis of 20 grams of Fructus Lycii of Rhizoma Zingiberis Recens
15 grams, 15 grams of Fructus Jujubaes of 15 grams of Cortex Ailanthis of Fructus Rosae Laevigatae
20 grams of 20 grams of Fructus Schisandrae Chinensis of 20 grams of Radix Angelicae Pubescentiss of Herba Pyrolae
10 grams of 10 grams of Semen Cuscutae of 10 grams of Colla cornus cervis of Herba Schizonepetae
15 grams of Radix Codonopsis
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Concha Ostreae: clean, dry, pulverize use;
2, Fluoritum: clean earth, smash into fritter;
3, Herba Ecliptae: choose clean impurity, remove undesirable root, clean vexed, cutting is dried;
4, Carapax Trionycis: be soaked in water, remove skin and flesh, clean, dry;
5, Folium Mori: choose decontamination, rub with the hands brokenly, winnow with a dustpan destemming, sieve removes spare;
6, Flos Celosiae Cristatae: choose clean impurity, remove stem and seed, be cut into small pieces;
7, Herba Agrimoniae: remove impurity undesirable root, clean, run through, cut off, dry;
8, Endoconcha Sepiae: scrub clean, dry, pound into fritter;
9, Radix Patriniae heterophyllae: excavate autumn, removes stem Seedling and earth, dries;
10, Exocarpium Litchi: choose clean impurity, dry;
11, Herba Cirsii: choose clean impurity, remove root, washing runs through, tangent plane dries;
12, the Radix Pulsatillae: choose clean impurity, clean, run through rear section, dry;
13, Fructus Mori: wash, choose decontamination, extract long handle, dry;
14, Os Draconis: outwash earth, smash;
15, Radix Notoginseng: choose clean impurity, smash to pieces, grind or run through rear section into powder and dry;
16, Radix Ginseng Rubra: get crude drug, run through, shave, dry;
17, Radix Rumicis Japonici: the 8-9 month gets, and chooses decontamination, dries;
18, Herba Chenopodii Hybridi: the 6-8 month gathers, chopping, dries;
19, Herba Capsellae: the 3-5 month gathers, cleans, and dries;
20, Semen Ziziphi Spinosae: former medicine is put into bamboo square-bottomed bamboo basket, sinks in clear water cylinder, and core is kept afloat, and shell is heavy water-bed, and Semen Ziziphi Spinosae is pulled out, dries;
21, Flos Chrysanthemi Indici: remove impurity, remove undesirable root, clean cutting, dry;
22, Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put in pot and fry and be black to outside, inside is strong yellow, slightly spills clear water, takes out, dry;
23, Terra Flava Usta: remove impurity, break into fragment;
24, Semen Benincasae: choose clean impurity, the used time smashs to pieces;
25, Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;
26, Fructus Lycii: the clean impurity of winnowing with a dustpan, pluck residual stalk and the base of a fruit;
27, Rhizoma Paridis: excavate autumn, removes fibrous root, cleaning, drying;
28, Fructus Rosae Laevigatae: choose decontamination, cut two lobes, water slightly soaks, and pulls out, removes residual burr after moistening, digs clean hair, core, dry;
29, Cortex Ailanthi: remove rough bark, impurity, clean, run through, shredding or piece, dry, sieve removes chip;
30, Fructus Jujubae: choose clean impurity, dry;
31, Herba Pyrolae: choose decontamination, sieve removes silt, cleans, and slightly profit, chops up, and dries;
32, Radix Angelicae Pubescentis: choose decontamination, separately size, cleans, and runs through rear section, dry;
33, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;
34, Herba Schizonepetae: choose clean impurity, water is bubble slightly, pulls cutting out, dries;
35, Colla cornus cervi: get crude drug, remove impurity, the used time smashs to pieces or levigation;
36, Semen Cuscutae: cross square-bottomed bamboo basket and remove impurity, clean, dry;
37, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry.
Two, preparation
1, by the Concha Ostreae of described weight, Fluoritum, Herba Ecliptae, Carapax Trionycis, Folium Mori, Flos Celosiae Cristatae, Herba Agrimoniae, Endoconcha Sepiae, Radix Patriniae heterophyllae, Exocarpium Litchi, Herba Cirsii, the Radix Pulsatillae, Fructus Mori, Os Draconis, Radix Notoginseng, Radix Ginseng Rubra, Radix Rumicis Japonici, Herba Chenopodii Hybridi, Herba Capsellae, Semen Ziziphi Spinosae, Flos Chrysanthemi Indici, Nodus Nelumbinis Rhizomatis, Terra Flava Usta, Semen Benincasae, Rhizoma Zingiberis Recens, Fructus Lycii, Rhizoma Paridis, Fructus Rosae Laevigatae, Cortex Ailanthi, Fructus Jujubae, Herba Pyrolae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Herba Schizonepetae, Colla cornus cervi, Semen Cuscutae, Radix Codonopsis medicine decocts with water secondary, add for the first time 8 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 40 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time.
2, the medicinal residues after filtering are for the first time added to 4 times of amounts of water, decoct boiling, then use slow fire boiling 35 minutes, filter to obtain decoction liquor for the second time.
3, twice decoction liquor mixing being divided into 6 doses takes.
Medicine of the present invention has removing heat from blood, hemostasis, and dissipating blood stasis, analgesic therapy, lowering the adverse flow of QI, the effect in warm uterus, treatment dysfunctional uterine hemorrhage instant effect, short treating period, do not recur.
By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.4kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit activities, diet are normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 221 examples for medical treatment.
2, diagnostic criteria
Clinical manifestation
(1) few when many during metrorrhagia blood volume at random, or sudden fast rush.Amenorrhea time elder, amount of bleeding is many, and the sustainable several months is more than, time while flowing only;
(2) health check-up edeoscopy is normal, or the slight increase in bilateral ovaries symmetry ground;
(3) basal body temperature is unipolar type;
(4) severe loss of blood can cause anemia, the phenomenon such as severe patient can occur dizziness, has palpitation, breathes hard, weak, edema, inappetence;
(5) discharge hormonosis, distending pain of the breast, lower abdomen falling inflation, excited etc.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, each serving with 1 dose, every day, early, middle and late respectively clothes 1 time, 7 days was a course for the treatment of, took continuously 4 courses for the treatment of.
4, efficacy assessment standard
Effective: dysfunctional uterine hemorrhage is eliminated, observe after half a year without recurrence;
Take a turn for the better: dysfunctional uterine hemorrhage symptom is clearly better;
Invalid: symptom, without improvement, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy functional uterine bleeding 221 examples of the present invention, effective 210 examples of result, obvious effective rate is 95.02%, 7 examples that take a turn for the better, and improvement rate is 3.17%, invalid 4 examples, total effective rate is 98.19%.
Claims (3)
1. a medicine for the treatment of dysfunctional uterine hemorrhage, is characterized in that: it is to be made by the crude drug in following weight range:
Concha Ostreae 15-25 gram of Fluoritum 15-25 gram of Herba Ecliptae 15-25 gram
Carapax Trionycis 10-20 gram of Folium Mori 10-20 gram of Flos Celosiae Cristatae 10-20 gram
Herba Agrimoniae 10-20 gram of Endoconcha Sepiae 10-20 gram of Radix Patriniae heterophyllae 10-20 gram
Exocarpium Litchi 10-20 gram of Herba Cirsii 5-15 gram of Radix Pulsatillae 5-15 gram
5-15 gram of Radix Notoginseng 5-15 gram of Fructus Mori 5-15 cron bone
Radix Ginseng Rubra 5-15 gram of Radix Rumicis Japonici 5-15 gram of Herba Chenopodii Hybridi 5-15 gram
Herba Capsellae 15-25 gram of Semen Ziziphi Spinosae 15-25 gram of Flos Chrysanthemi Indici 15-25 gram
Nodus Nelumbinis Rhizomatis 15-25 gram of Terra Flava Usta 15-25 gram of Semen Benincasae 15-25 gram
Rhizoma Zingiberis Recens 15-25 gram of Fructus Lycii 15-25 gram of Rhizoma Paridis 15-25 gram
Fructus Rosae Laevigatae 10-20 gram of Cortex Ailanthi 10-20 gram of Fructus Jujubae 10-20 gram
Herba Pyrolae 15-25 gram of Radix Angelicae Pubescentis 15-25 gram of Fructus Schisandrae Chinensis 15-25 gram
Herba Schizonepetae 5-15 gram of Colla cornus cervi 5-15 gram of Semen Cuscutae 5-15 gram
Radix Codonopsis 10-20 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
20 grams of 20 grams of Herba Ecliptaes of 20 grams of Fluoritum of Concha Ostreae
15 grams of 15 grams of Flos Celosiae Cristataes of 15 grams of Folium Mori of Carapax Trionycis
15 grams of 15 grams of Radix Patriniae heterophyllaes of 15 grams of Endoconcha Sepiaes of Herba Agrimoniae
10 grams of 10 grams of Radix Pulsatillaes of 15 grams of Herba Cirsiis of Exocarpium Litchi
10 grams of 10 grams of Radix Notoginseng of Fructus Mori 10 cron bone
10 grams of 10 grams of Herba Chenopodii Hybridis of 10 grams of Radix Rumicis Japonicis of Radix Ginseng Rubra
20 grams of 20 grams of Flos Chrysanthemi Indicis of 20 grams of Semen Ziziphi Spinosaes of Herba Capsellae
20 grams of 20 grams of Semen Benincasaes of 20 grams of Terra Flava Ustas of Nodus Nelumbinis Rhizomatis
20 grams of 20 grams of Rhizoma Paridis of 20 grams of Fructus Lycii of Rhizoma Zingiberis Recens
15 grams, 15 grams of Fructus Jujubaes of 15 grams of Cortex Ailanthis of Fructus Rosae Laevigatae
20 grams of 20 grams of Fructus Schisandrae Chinensis of 20 grams of Radix Angelicae Pubescentiss of Herba Pyrolae
10 grams of 10 grams of Semen Cuscutae of 10 grams of Colla cornus cervis of Herba Schizonepetae
15 grams of Radix Codonopsis.
3. according to the preparation method of medicine described in claim 1 or 2, it is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Concha Ostreae: clean, dry, pulverize use;
(2) Fluoritum: clean earth, smash into fritter;
(3) Herba Ecliptae: choose clean impurity, remove undesirable root, clean vexed, cutting is dried;
(4) Carapax Trionycis: be soaked in water, remove skin and flesh, clean, dry;
(5) Folium Mori: choose decontamination, rub with the hands brokenly, winnow with a dustpan destemming, sieve removes spare;
(6) Flos Celosiae Cristatae: choose clean impurity, remove stem and seed, be cut into small pieces;
(7) Herba Agrimoniae: remove impurity undesirable root, clean, run through, cut off, dry;
(8) Endoconcha Sepiae: scrub clean, dry, pound into fritter;
(9) Radix Patriniae heterophyllae: excavate autumn, removes stem Seedling and earth, dries;
(10) Exocarpium Litchi: choose clean impurity, dry;
(11) Herba Cirsii: choose clean impurity, remove root, washing runs through, tangent plane dries;
(12) Radix Pulsatillae: choose clean impurity, clean, run through rear section, dry;
(13) Fructus Mori: wash, choose decontamination, extract long handle, dry;
(14) Os Draconis: outwash earth, smash;
(15) Radix Notoginseng: choose clean impurity, smash to pieces, grind or run through rear section into powder and dry;
(16) Radix Ginseng Rubra: get crude drug, run through, shave, dry;
(17) Radix Rumicis Japonici: the 8-9 month gets, and chooses decontamination, dries;
(18) Herba Chenopodii Hybridi: the 6-8 month gathers, chopping, dries;
(19) Herba Capsellae: the 3-5 month gathers, cleans, and dries;
(20) Semen Ziziphi Spinosae: former medicine is put into bamboo square-bottomed bamboo basket, sinks in clear water cylinder, and core is kept afloat, and shell is heavy water-bed, and Semen Ziziphi Spinosae is pulled out, dries;
(21) Flos Chrysanthemi Indici: remove impurity, remove undesirable root, clean cutting, dry;
(22) Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put in pot and fry and be black to outside, inside is strong yellow, slightly spills clear water, takes out, dry;
(23) Terra Flava Usta: remove impurity, break into fragment;
(24) Semen Benincasae: choose clean impurity, the used time smashs to pieces;
(25) Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;
(26) Fructus Lycii: the clean impurity of winnowing with a dustpan, pluck residual stalk and the base of a fruit;
(27) Rhizoma Paridis: excavate autumn, removes fibrous root, cleaning, drying;
(28) Fructus Rosae Laevigatae: choose decontamination, cut two lobes, water slightly soaks, and pulls out, removes residual burr after moistening, digs clean hair, core, dry;
(29) Cortex Ailanthi: remove rough bark, impurity, clean, run through, shredding or piece, dry, sieve removes chip;
(30) Fructus Jujubae: choose clean impurity, dry;
(31) Herba Pyrolae: choose decontamination, sieve removes silt, cleans, and slightly profit, chops up, and dries;
(32) Radix Angelicae Pubescentis: choose decontamination, separately size, cleans, and runs through rear section, dry;
(33) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;
(34) Herba Schizonepetae: choose clean impurity, water is bubble slightly, pulls cutting out, dries;
(35) Colla cornus cervi: get crude drug, remove impurity, the used time smashs to pieces or levigation;
(36) Semen Cuscutae: cross square-bottomed bamboo basket and remove impurity, clean, dry;
(37) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(2) preparation
(1) by the Concha Ostreae of described weight, Fluoritum, Herba Ecliptae, Carapax Trionycis, Folium Mori, Flos Celosiae Cristatae, Herba Agrimoniae, Endoconcha Sepiae, Radix Patriniae heterophyllae, Exocarpium Litchi, Herba Cirsii, the Radix Pulsatillae, Fructus Mori, Os Draconis, Radix Notoginseng, Radix Ginseng Rubra, Radix Rumicis Japonici, Herba Chenopodii Hybridi, Herba Capsellae, Semen Ziziphi Spinosae, Flos Chrysanthemi Indici, Nodus Nelumbinis Rhizomatis, Terra Flava Usta, Semen Benincasae, Rhizoma Zingiberis Recens, Fructus Lycii, Rhizoma Paridis, Fructus Rosae Laevigatae, Cortex Ailanthi, Fructus Jujubae, Herba Pyrolae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Herba Schizonepetae, Colla cornus cervi, Semen Cuscutae, Radix Codonopsis medicine decocts with water secondary, add for the first time 8 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 40 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time,
(2) medicinal residues after filtering are for the first time added to 4 times of amounts of water, decoct boiling, then use slow fire boiling 35 minutes, filter to obtain decoction liquor for the second time;
(3) twice decoction liquor mixing being divided into 6 doses takes.
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| CN103041306A (en) * | 2012-12-30 | 2013-04-17 | 青岛恒波仪器有限公司 | Traditional Chinese medicine composition for curing climacteric syndrome of women and preparation method thereof |
| CN103285172A (en) * | 2013-05-24 | 2013-09-11 | 上海市中医医院 | Chinese medicament composition for treating myoma of uterus and endometrial cancer and application thereof |
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| CN103041306A (en) * | 2012-12-30 | 2013-04-17 | 青岛恒波仪器有限公司 | Traditional Chinese medicine composition for curing climacteric syndrome of women and preparation method thereof |
| CN103285172A (en) * | 2013-05-24 | 2013-09-11 | 上海市中医医院 | Chinese medicament composition for treating myoma of uterus and endometrial cancer and application thereof |
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| 宋红湘: "固冲汤加减治疗功能性子宫出血100例", 《中医研究》, vol. 17, no. 06, 25 December 2004 (2004-12-25), pages 42 * |
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