CN1035255C - 杂三环衍生物 - Google Patents

杂三环衍生物 Download PDF

Info

Publication number
CN1035255C
CN1035255C CN93102389A CN93102389A CN1035255C CN 1035255 C CN1035255 C CN 1035255C CN 93102389 A CN93102389 A CN 93102389A CN 93102389 A CN93102389 A CN 93102389A CN 1035255 C CN1035255 C CN 1035255C
Authority
CN
China
Prior art keywords
compound
salt
carbonyl
following formula
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN93102389A
Other languages
English (en)
Chinese (zh)
Other versions
CN1087639A (zh
Inventor
松尾昌昭
辻喜良
中村克哉
G·W·施皮尔斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929201836A external-priority patent/GB9201836D0/en
Priority claimed from GB929224012A external-priority patent/GB9224012D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of CN1087639A publication Critical patent/CN1087639A/zh
Application granted granted Critical
Publication of CN1035255C publication Critical patent/CN1035255C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN93102389A 1992-01-27 1993-01-26 杂三环衍生物 Expired - Fee Related CN1035255C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB929201836A GB9201836D0 (en) 1992-01-27 1992-01-27 Heterotricyclic derivatives
GB9224012.6 1992-11-16
GB9201836.5 1992-11-16
GB929224012A GB9224012D0 (en) 1992-11-16 1992-11-16 Heterotricyclic derivatives

Publications (2)

Publication Number Publication Date
CN1087639A CN1087639A (zh) 1994-06-08
CN1035255C true CN1035255C (zh) 1997-06-25

Family

ID=26300222

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93102389A Expired - Fee Related CN1035255C (zh) 1992-01-27 1993-01-26 杂三环衍生物

Country Status (11)

Country Link
US (2) US5583135A (en:Method)
EP (1) EP0625983A1 (en:Method)
JP (1) JP3175164B2 (en:Method)
KR (1) KR950700310A (en:Method)
CN (1) CN1035255C (en:Method)
AU (1) AU664068B2 (en:Method)
CA (1) CA2128779A1 (en:Method)
HU (2) HUT70852A (en:Method)
MX (1) MX9300399A (en:Method)
TW (1) TW222276B (en:Method)
WO (1) WO1993015083A1 (en:Method)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9311562D0 (en) * 1993-06-04 1993-07-21 Fujisawa Pharmaceutical Co Heterocyclic derivatives
GB9404378D0 (en) * 1994-03-07 1994-04-20 Fujisawa Pharmaceutical Co Quinoline derivatives
DE4424369A1 (de) * 1994-07-11 1996-01-18 Bayer Ag Pyrido[3,2,1.i,j][3,1]benzoxazinderivate
JP2000103793A (ja) * 1998-07-31 2000-04-11 Kyorin Pharmaceut Co Ltd ピリドベンゾチアジン誘導体及びその製造方法
JP2000103792A (ja) * 1998-07-31 2000-04-11 Kyorin Pharmaceut Co Ltd ピリドベンゾオキサジン誘導体及びその製造方法
TW500724B (en) * 1999-10-05 2002-09-01 Pharmacia & Amp Upjohn Company Oxazinoquinolones useful for the treatment of viral infections
AU2001252671A1 (en) * 2000-05-12 2001-11-20 Kyorin Pharmaceutical Co. Ltd. Pyridobenzodiazine derivatives and processes for the preparation thereof
US6673793B2 (en) 2000-07-12 2004-01-06 Pharmacia & Upjohn Co. Oxazinoquinolones useful for the treatment of viral infections
US6821969B2 (en) * 2001-02-13 2004-11-23 Pharmacia & Upjohn Company Thioxazinoquinolones as antiviral agents
WO2004104000A1 (ja) * 2003-05-23 2004-12-02 Japan Tobacco Inc. トリサイクリック縮合環化合物およびその医薬用途
US20110223131A1 (en) * 2010-02-24 2011-09-15 Gilead Sciences, Inc. Antiviral compounds
RU2013120556A (ru) 2010-10-14 2014-11-20 Иммунар Аб 1,2-гидрокси-2-оксо-хинолин-3-карбоксанилиды в качестве активаторов ahr
RU2720237C2 (ru) 2013-11-18 2020-04-28 Форма Терапеутикс, Инк. Композиции, содержащие бензопиперазин, в качестве ингибиторов бромодоменов вет
HUE053645T2 (hu) 2013-11-18 2021-07-28 Forma Therapeutics Inc Tetrahidrokinolin kompozíciók mint BET bromodomén inhibitorok
WO2016045127A1 (en) * 2014-09-28 2016-03-31 Merck Sharp & Dohme Corp. Inhibitors of hif prolyl hydroxylase
CN120987969A (zh) * 2024-05-21 2025-11-21 中国药科大学 一类蛋白靶向降解嵌合体及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA319032A (en) * 1932-01-19 R. Lynch Elmer Overhead door
GB912289A (en) * 1959-06-09 1962-12-05 Geigy Ag J R New basic ethers and processes for their production
EP0059698A1 (en) * 1981-03-03 1982-09-08 Ab Leo Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322417A (en) * 1977-12-22 1982-03-30 E. I. Du Pont De Nemours And Company Antihypertensive polyfluoroisopropyl tricyclic carbostyrils

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA319032A (en) * 1932-01-19 R. Lynch Elmer Overhead door
GB912289A (en) * 1959-06-09 1962-12-05 Geigy Ag J R New basic ethers and processes for their production
EP0059698A1 (en) * 1981-03-03 1982-09-08 Ab Leo Heterocyclic carboxamides, compositions containing such compounds, processes for their preparation and methods of treatment therewith

Also Published As

Publication number Publication date
JPH07503248A (ja) 1995-04-06
HU211982A9 (en) 1996-01-29
CA2128779A1 (en) 1993-08-05
WO1993015083A1 (en) 1993-08-05
TW222276B (en:Method) 1994-04-11
AU3367593A (en) 1993-09-01
KR950700310A (ko) 1995-01-16
US5739130A (en) 1998-04-14
HU9402187D0 (en) 1994-09-28
MX9300399A (es) 1993-07-01
CN1087639A (zh) 1994-06-08
EP0625983A1 (en) 1994-11-30
US5583135A (en) 1996-12-10
AU664068B2 (en) 1995-11-02
HUT70852A (en) 1995-11-28
JP3175164B2 (ja) 2001-06-11

Similar Documents

Publication Publication Date Title
CN1035255C (zh) 杂三环衍生物
CN1072220C (zh) 作为神经激肽受体拮抗剂的1－苯甲酰基－2－(吲哚基－3－烷基)－哌嗪衍生物
CN1031570C (zh) 吡唑并吡啶化合物的制备方法
CN1042730C (zh) 吡唑并吡啶化合物的制备方法
CN1046724C (zh) 吡唑并吡啶化合物、含有它们的药物组合物、及其制法与用途
CN1260225C (zh) 四氢吡啶基或哌啶基杂环衍生物
CN1022187C (zh) 三环化合物的制备方法
CN1304375C (zh) 用作jnk抑制剂的吡唑并蒽酮及其衍生物和它们的组合物
CN1185232C (zh) αLβ2介导细胞粘连抑制剂
CN1061658C (zh) 三环苯并吖庚因加压素拮抗剂
CN1114598C (zh) 芳族化合物和含有它们的药物组合物
CN1906189A (zh) 用于治疗呼吸系统疾病的1－乙酸－吲哚、－吲唑和－苯并咪唑衍生物
CN1483024A (zh) Vla-4抑制剂
CN101035785A (zh) 具有抗菌活性的新化合物
CN1161334A (zh) 新的取代胍衍生物，其制备方法和其药物用途)
CN1307571A (zh) 胍衍生物
CN1025500C (zh) 杂芳基3-氧-丙腈衍生物的制备方法
CN1202171A (zh) 吡啶并[2,3－d]嘧啶衍生物及其医药组合物
CN1761670A (zh) 新化合物
CN1217723A (zh) 二氮杂䓬酮、其生产和用途
CN1067892A (zh) 新的吡咯并[2，3-b]吡啶衍生物的制备方法
CN1205702A (zh) 吡啶并(2,3－b)吡嗪衍生物
CN1008738B (zh) 头孢菌素衍生物的制备方法
CN1278820A (zh) 作为嗜中性粒细胞弹性蛋白酶抑制剂的吡咯并吡咯酮衍生物
CN1993358A (zh) 作为趋化因子受体拮抗剂的噻唑衍生物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee