CN103505490B - A kind of cleaning wound liquid - Google Patents
A kind of cleaning wound liquid Download PDFInfo
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- CN103505490B CN103505490B CN201210203351.3A CN201210203351A CN103505490B CN 103505490 B CN103505490 B CN 103505490B CN 201210203351 A CN201210203351 A CN 201210203351A CN 103505490 B CN103505490 B CN 103505490B
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- cleaning wound
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- wound liquid
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- 239000007788 liquid Substances 0.000 title claims abstract description 32
- 238000004140 cleaning Methods 0.000 title claims abstract description 31
- 230000003204 osmotic effect Effects 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000008367 deionised water Substances 0.000 claims abstract description 9
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 9
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 9
- 239000000203 mixture Substances 0.000 claims description 11
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical group [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 239000003002 pH adjusting agent Substances 0.000 claims description 4
- 238000005538 encapsulation Methods 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 206010052428 Wound Diseases 0.000 abstract description 37
- 208000027418 Wounds and injury Diseases 0.000 abstract description 37
- 239000000284 extract Substances 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 7
- 230000001954 sterilising effect Effects 0.000 abstract description 6
- 230000029663 wound healing Effects 0.000 abstract description 5
- 229940069521 aloe extract Drugs 0.000 abstract description 4
- 230000003110 anti-inflammatory effect Effects 0.000 abstract description 4
- 239000001522 artemisia absinthium l. herb extract Substances 0.000 abstract description 4
- 229940119569 wormwood extract Drugs 0.000 abstract description 4
- 230000036592 analgesia Effects 0.000 abstract description 2
- 231100000241 scar Toxicity 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 239000001963 growth medium Substances 0.000 description 5
- 229920001817 Agar Polymers 0.000 description 4
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 4
- 229920001661 Chitosan Polymers 0.000 description 4
- 239000008272 agar Substances 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 241000222122 Candida albicans Species 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 241000191963 Staphylococcus epidermidis Species 0.000 description 3
- 229940095731 candida albicans Drugs 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 230000036407 pain Effects 0.000 description 3
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 2
- 241001116389 Aloe Species 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 2
- 229930182566 Gentamicin Natural products 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- 206010053692 Wound complication Diseases 0.000 description 2
- 235000011399 aloe vera Nutrition 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000011630 iodine Substances 0.000 description 2
- 229910052740 iodine Inorganic materials 0.000 description 2
- 238000002663 nebulization Methods 0.000 description 2
- -1 oxonium ion Chemical class 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 235000002639 sodium chloride Nutrition 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000000638 solvent extraction Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 235000019154 vitamin C Nutrition 0.000 description 2
- 239000011718 vitamin C Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- KZJWDPNRJALLNS-VPUBHVLGSA-N (-)-beta-Sitosterol Natural products O[C@@H]1CC=2[C@@](C)([C@@H]3[C@H]([C@H]4[C@@](C)([C@H]([C@H](CC[C@@H](C(C)C)CC)C)CC4)CC3)CC=2)CC1 KZJWDPNRJALLNS-VPUBHVLGSA-N 0.000 description 1
- CSVWWLUMXNHWSU-UHFFFAOYSA-N (22E)-(24xi)-24-ethyl-5alpha-cholest-22-en-3beta-ol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(CC)C(C)C)C1(C)CC2 CSVWWLUMXNHWSU-UHFFFAOYSA-N 0.000 description 1
- KLEXDBGYSOIREE-UHFFFAOYSA-N 24xi-n-propylcholesterol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CCC)C(C)C)C1(C)CC2 KLEXDBGYSOIREE-UHFFFAOYSA-N 0.000 description 1
- AWXFHJXPYIPUSS-UHFFFAOYSA-N 3,5,6-trimethoxy-2-phenylchromen-4-one Chemical compound COC=1C(=O)C2=C(OC)C(OC)=CC=C2OC=1C1=CC=CC=C1 AWXFHJXPYIPUSS-UHFFFAOYSA-N 0.000 description 1
- FRXSZNDVFUDTIR-UHFFFAOYSA-N 6-methoxy-1,2,3,4-tetrahydroquinoline Chemical compound N1CCCC2=CC(OC)=CC=C21 FRXSZNDVFUDTIR-UHFFFAOYSA-N 0.000 description 1
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
- LPZCCMIISIBREI-MTFRKTCUSA-N Citrostadienol Natural products CC=C(CC[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4[C@H](C)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C LPZCCMIISIBREI-MTFRKTCUSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- ARVGMISWLZPBCH-UHFFFAOYSA-N Dehydro-beta-sitosterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)CCC(CC)C(C)C)CCC33)C)C3=CC=C21 ARVGMISWLZPBCH-UHFFFAOYSA-N 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- 241001479543 Mentha x piperita Species 0.000 description 1
- 241001597008 Nomeidae Species 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000002605 anti-dotal effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- MJVXAPPOFPTTCA-UHFFFAOYSA-N beta-Sistosterol Natural products CCC(CCC(C)C1CCC2C3CC=C4C(C)C(O)CCC4(C)C3CCC12C)C(C)C MJVXAPPOFPTTCA-UHFFFAOYSA-N 0.000 description 1
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 description 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 239000001110 calcium chloride Substances 0.000 description 1
- 229910001628 calcium chloride Inorganic materials 0.000 description 1
- 235000011148 calcium chloride Nutrition 0.000 description 1
- 210000000589 cicatrix Anatomy 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000001408 fungistatic effect Effects 0.000 description 1
- 230000000025 haemostatic effect Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 210000000578 peripheral nerve Anatomy 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 description 1
- 229950005143 sitosterol Drugs 0.000 description 1
- NLQLSVXGSXCXFE-UHFFFAOYSA-N sitosterol Natural products CC=C(/CCC(C)C1CC2C3=CCC4C(C)C(O)CCC4(C)C3CCC2(C)C1)C(C)C NLQLSVXGSXCXFE-UHFFFAOYSA-N 0.000 description 1
- 235000015500 sitosterol Nutrition 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 238000000194 supercritical-fluid extraction Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a kind of cleaning wound liquid, it comprises active component, osmotic pressure regulator and deionized water; Described active component is one or more in wormwood extract, Aloe extract, Folium Menthae extract.Cleaning wound liquid provided by the invention is non-stimulated to wound, namely can clean a wound, and has again sterilization, antiinflammatory, analgesia, the effect of promotion wound healing, not easily scar.
Description
Technical field
The present invention relates to a kind of cleaning wound liquid.
Background technology
In prior art, be mainly for the medicine cleaned a wound: hydrogen peroxide, iodine liquid, ethanol, normal saline, gentamycin washing liquid etc.Although hydrogen peroxide, iodine liquid, ethanol have the effect of sterilizing, but pain very can be felt when cleaning a wound, this is because: the oxonium ion in hydrogen peroxide has strong Oxidation, the direct stimulation of oxonium ion and oxygen are formed and disperse in tissue in a large number, wound tension force is increased, and pain increases the weight of; Ethanol, iodine tincture have very strong zest, especially skin are had to the wound of defect.And normal saline can only clean a wound on dirty, do not have sterilize function; Gentamycin is antibiotic type washing liquid, often uses, easily produces drug resistance.
Summary of the invention
The object of the invention is at least to solve one of technical problem existed in prior art.
For this reason, the invention provides a kind of cleaning wound liquid, composition and the content of described cleaning wound liquid are:
Simultaneously, the present invention also provides a kind of preparation method of above-mentioned cleaning wound liquid, first active component, osmotic pressure regulator is proportionally mixed, and is dissolved to mix homogeneously with deionized water, then add pH adjusting agent adjust ph to 6.5-7.5, finally carry out disinfection encapsulation.
Cleaning wound liquid of the present invention adopts natural Chinese herbal medicine formula, non-stimulated to wound, namely can clean a wound, and has again the effect of sterilization, antiinflammatory, analgesia, promotion wound healing; Not easily scar.
Detailed description of the invention
In order to make technical problem solved by the invention, technical scheme and beneficial effect clearly understand, below in conjunction with embodiment, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
A kind of cleaning wound liquid, comprises active component, osmotic pressure regulator and deionized water; Described active component is one or more in wormwood extract, Aloe extract, Folium Menthae extract.
Wormwood extract contains multiple sesquiterpenoids derivant, as: Folium Artemisiae Argyi element, artemetine, β ?sitosterol and 5,7 ?Er Qiang ?6,3', 4' ， ?trimethoxy flavone etc., it has hemostasis, antiallergic, antibacterial effect.
Containing number of chemical composition in Aloe extract, there is sterilization, antiinflammatory, antidotal effect, be conducive to wound and recover, reduce the formation of cicatrix.
Containing Peppermint essential oil in Folium Menthae extract, have peat-reek, the distinctive pungent sense of Herba Menthae and cool feeling can stimulate peripheral nerve, cause blood capillary to shrink to reflexive, thus reach antiinflammatory, alleviation wound pain, antipruritic effect.
The extracting method of wormwood extract and Folium Menthae extract generally has: organic solvent extraction: take Organic substance as the effective ingredient in solvent extraction Folium Artemisiae Argyi and Herba Menthae.Water extract method: be namely solvent with aqueous solution, effective component extracting at certain pressure, time, temperature.Supercritical extraction: the method replacing Conventional solvents to extract target components with supercritical fluid, existing research mostly is CO
2extraction.In some researchs, coordinate microwave and ultrasound mode assisted extraction, extraction efficiency and extractive content can be improved.
The extracting method of Aloe extract generally has: the sedimentation method: after smashing to pieces Aloe with pulverizer, carries out precipitating with high speed centrifuge.Nebulization: be drying to obtain by nebulization after aloe leaf is entered cryoconcentration.
The extracting method of these extracts is conventionally known to one of skill in the art, is not described in detail at this.In the extract of different extracting method gained, the content of effective ingredient can be slightly different, but it does not affect the effect of each extract in cleaning wound liquid.
Preferably, also chitosan is comprised.Chitosan molecule surface, with positive charge, can be adsorbed the negative charge that erythrocyte itself has, thus its coagulation is lumpd, thus reach haemostatic effect; Meanwhile, the main component on chitosan molecule chain is glucamine, and it promotes that wound healing effect is excellent.
Preferably, also vitamin C is comprised.Vitamin C is water solublity powerful antioxidant, and it participates in the synthesis of collagen protein, contributes to the healing of human body wound.Chitosan can promote blood coagulation, has sterilizing, promotes wound healing, absorbs the effects such as Wound exudate, not easily syneresis.
As preferred further, in cleaning wound liquid provided by the invention, the content of each component is: the active component of 3.25-7.4wt%; The osmotic pressure regulator of 0.6-0.9wt%, all the other are deionized water.Cleaning wound liquid excellent effect in this content range.Preferred, the content of active component is 4.0-6.8wt%.
Cleaning wound liquid will reach does not have zest to human body, just requires that its osmotic pressure is equal with the osmotic pressure of human plasma.In the present invention, regulated the osmotic pressure of cleaning wound liquid by osmotic pressure regulator, osmotic pressure regulator is preferably sodium chloride, potassium chloride, calcium chloride, sodium bicarbonate or sodium dihydrogen phosphate.More preferably adopt sodium chloride to regulate the osmotic pressure of cleaning wound liquid, consumption is 0.6-0.9%wt%, preferably 0.85-0.9wt%.
Preferably, the composition of described cleaning wound liquid and content are:
Simultaneously, the present invention also provides a kind of preparation method of above-mentioned cleaning wound liquid, first active component, osmotic pressure regulator is proportionally mixed, and is dissolved to mix homogeneously with deionized water, then add pH adjusting agent adjust ph to 6.5-7.5, finally carry out disinfection encapsulation.By its pH regulator to 6.5-7.5, to adapt to human body, in the present invention, pH value regulator is preferably NaOH or HCl.Disinfecting as known in those skilled in the art of medicine, is not described in detail at this.
Below by specific embodiment, the present invention is described in further detail.
Embodiment 1
Each composition is mixed according to following ratio, with deionized water dissolving and mix homogeneously.PH is regulated to be the subpackage that carries out disinfection after 6.8.
Embodiment 2
Each composition is mixed according to following ratio, with deionized water dissolving and mix homogeneously.PH is regulated to be the subpackage that carries out disinfection after 7.2.
Embodiment 3
Each composition is mixed according to following ratio, with deionized water dissolving and mix homogeneously.PH is regulated to be the subpackage that carries out disinfection after 7.5.
Performance test
1, pain test:
Randomly drawing 150 experimenters adopts the cleaning wound liquid of embodiment 1 ?3 to carry out cleaning wound, and the people of 90% does not feel the prick in cleaning process, and wound pain degree reduces;
Need to illustrate that speed of wound healing is also fast than the healing rate not carrying out cleaning wound in addition.
2, bacteriostasis property test:
By embodiment 1 ?3 cleaning wound liquid join with aseptic straw respectively in the culture dish of sterilizing, then add the agar culture medium of same volume, abundant mix homogeneously.After culture medium cooling, at the lid of alcohol burner front opening culture dish, examination bacterium liquid (strain is staphylococcus aureus, staphylococcus epidermidis, escherichia coli, green pus bacterium and Candida albicans) is coated radially successively with Inoculating needle, cover the lid of culture dish, cultivate under 37 DEG C of constant temperature 24 ?48 hours, observe the growing state of thalline, make blank with the agar culture medium not containing cleaning wound liquid.
Through observing, have in the agar culture medium of the cleaning wound liquid that embodiment 1-embodiment 3 provides and find a small amount of staphylococcus aureus, staphylococcus epidermidis, escherichia coli, green pus bacterium and Candida albicans, be far smaller than not containing the staphylococcus aureus in the agar culture medium of cleaning wound liquid, staphylococcus epidermidis, escherichia coli, green pus bacterium and Candida albicans quantity, illustrate that cleaning wound liquid provided by the invention has good fungistatic effect.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, therefore, as long as any amendment of using the content of description of the present invention to do, equivalent replacement and improvement etc., all should protection scope of the present invention be included in.
Claims (2)
1. a cleaning wound liquid, is characterized in that, composition and the content of described cleaning wound liquid are:
2. the preparation method of a cleaning wound liquid according to claim 1, it is characterized in that, first active component, osmotic pressure regulator are proportionally mixed, and be dissolved to mix homogeneously with deionized water, then pH adjusting agent adjust ph to 6.5-7.5 are added, wherein, described pH adjusting agent is NaOH or HCl, and finally carry out disinfection encapsulation.
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| CN201210203351.3A CN103505490B (en) | 2012-06-20 | 2012-06-20 | A kind of cleaning wound liquid |
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| CN201210203351.3A CN103505490B (en) | 2012-06-20 | 2012-06-20 | A kind of cleaning wound liquid |
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| CN103505490B true CN103505490B (en) | 2016-04-27 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105477497A (en) * | 2014-09-19 | 2016-04-13 | 李玉兰 | Traditional Chinese medicine composition for hand wound treatment |
| CN104758202A (en) * | 2015-03-09 | 2015-07-08 | 胡建华 | A detergent containing plant extract products and a preparing method thereof |
| CN105107007B (en) * | 2015-08-26 | 2017-12-19 | 东莞市达庆医疗器械有限公司 | A kind of medical protective dressing of cation and preparation method thereof |
| CN105126107A (en) * | 2015-09-21 | 2015-12-09 | 山东威高药业股份有限公司 | Liquid wound dressing |
| CN105878673A (en) * | 2016-04-25 | 2016-08-24 | 李增梅 | Traditional Chinese medicine cleaning solution for nursing |
| CN105830766A (en) * | 2016-04-26 | 2016-08-10 | 江苏东珠景观股份有限公司 | Rejuvenation method of ancient and famous trees |
| CN106860401A (en) * | 2017-02-09 | 2017-06-20 | 林映津 | A kind of pure natural wound restoration agent |
| CN109674816A (en) * | 2018-12-17 | 2019-04-26 | 东元科技有限公司 | A kind of composite antibacterial aerosol and its preparation method and application |
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| CN1559580A (en) * | 2004-03-01 | 2005-01-05 | 福建省泉州亚泰制药有限公司 | Production technology of medicine for treating burn |
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