CN104586682A - Antibacterial deodorant cosmetic composition and preparation method thereof - Google Patents
Antibacterial deodorant cosmetic composition and preparation method thereof Download PDFInfo
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- CN104586682A CN104586682A CN201410821737.XA CN201410821737A CN104586682A CN 104586682 A CN104586682 A CN 104586682A CN 201410821737 A CN201410821737 A CN 201410821737A CN 104586682 A CN104586682 A CN 104586682A
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Abstract
The invention discloses an antibacterial deodorant cosmetic composition which comprises the following components in parts by weight: 1-40 parts of a plant extracting solution, 5-15 parts of a moisturizer, 0.05-0.15 part of a thickening agent, 0.1-0.2 part of an anti-inflammatory agent, 0.09-0.11 part of a neutralizer, 0.2-0.7 part of a preservative and 50-80 parts of water, wherein the plant extracting solution refers to a mixed solution of common vladimiria root extracting solution, a pogostemon cablin extracting solution, an oregano extracting solution and an evening primrose extracting solution. The mixed solution of the common vladimiria root extracting solution, the pogostemon cablin extracting solution, the oregano extracting solution and the evening primrose extracting solution is added into the antibacterial deodorant cosmetic composition, the antibacterial deodorant cosmetic composition is natural and mild in components, synergistic and stable in system, serves as a type of novel foot antibacterial deodorant cosmetics, can kill fungi, candida, moulds, bacteria and multiple dermatophytes, has the effects of effectively inhibiting bacteria and deodorizing and is convenient to use.
Description
Technical field
The present invention relates to cosmetic field, particularly relate to a kind of bacteriostasis, and deodorization cosmetic composition and preparation method thereof.
Background technology
People needs foot to walk every day, and foot is the important component part of the person; Beriberi is a kind of extremely common fungal infection dermatoses.In adult, the people of 70-80% has beriberi, and just weight is different.Beriberi (foot odor) is because the eccrine secretion of health is vigorous, sweat gland secretion thing antibacterial, mycete, fungus, read coccus divide take off produce dirty smelly.Perspiration impels antibacterial easily to breed, and therefore normal the and hyperhidrosis of foot odor occurs together.
Current foot bacteriostatic deodorising product mostly is medicated powder and removes foot odor liquid, and the using method of medicated powder, for being sprinkled upon on shoe pad, can not suppress the breeding of foot fungi, poor effect well, and medicated powder composition zest is large, can not protect pedal skin very well; Go foot odor liquid to use inconvenient, foot can not be broken off because of daily footwear of wearing and perspire and the fungus breeding that causes, produce stink.In addition, existing except beriberi product can only be single for its inhibitory action of one or both dermatophytosises.
Beriberi makes a lot of people be perplexed, and develop a kind of natural gentleness, safe and effective, easy to use, the bacteriostasis, and deodorization cosmetics killing various skin tinea bacterium become a difficult problem urgently to be resolved hurrily.
Summary of the invention
In order to overcome above-mentioned the deficiencies in the prior art, the present invention adopts modern study means, provides bacteriostasis, and deodorization cosmetic composition of a kind of natural safe, four kinds of natural plant extracts Synergistics and preparation method thereof.
The present invention to solve the problem adopt technical scheme be to provide a kind of bacteriostasis, and deodorization cosmetic composition, this cosmetic composition by weight, comprises following component:
Wherein, described plant extraction liquid is the mixed liquor of Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution.
Wherein in some embodiments, the weight portion of described plant extraction liquid is 10 ~ 30 parts; The weight part ratio of described Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution is (0.5 ~ 10): (0.5 ~ 10): (0.5 ~ 10): (0.5 ~ 10).
Wherein in some embodiments, the weight part ratio of described Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution is (2 ~ 10): (2 ~ 10): (2 ~ 10): (2 ~ 10).
Wherein in some embodiments, described thickening agent is carbomer; Described nertralizer is triethanolamine; Described antiseptic is propylene glycol/diazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate.
Wherein in some embodiments, described wetting agent is weight part ratio is (5 ~ 10): (3 ~ 5): the mixing of the glycerol of (0.01 ~ 0.03), propylene glycol, hyaluronate sodium.
Wherein in some embodiments, described antiinflammatory is weight part ratio is (0.05 ~ 0.1): the allantoin of (0.05 ~ 0.1) and the mixing of Flos Inulae extract.
Radix Vladimiriae extracting solution of the present invention, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution can by conventional alcohol extracting method preparations, effect performance of four kinds of extracting solution is ensured to greatest extent with this, preferred following extracting method: it is in the ethanol of 85% that the plant (Radix Vladimiriae, Herba Pogostemonis, Adeps Bovis seu Bubali and Radix Oenotherae erythrosepalae) of drying is joined mass ratio, carries out extraction 4 ~ 8h under backflow and dipping.Subsequently, with filter cloth, extracting solution is filtered, more namely centrifugalize obtains plant (Radix Vladimiriae, Herba Pogostemonis, Adeps Bovis seu Bubali and Radix Oenotherae erythrosepalae) extracting solution.
The preparation method of above-mentioned bacteriostasis, and deodorization cosmetic composition, comprises the steps:
(1) wetting agent, thickening agent mixing is scattered, add water, be heated to 80 ~ 90 DEG C, 4000 revs/min after homogenizing 5-10 minute, constant temperature 85 DEG C, 50 revs/min are stirred after 30-40 minute and start cooling;
(2) be cooled to 50-55 DEG C, add antiinflammatory, stir;
(3) be cooled to 40-45 DEG C, add nertralizer, stir;
(4) add plant extraction liquid and antiseptic, stir, obtain bacteriostasis, and deodorization cosmetic composition.
Radix Vladimiriae is the dry root of Compositae Dolomiaea plant Radix Vladimiriae, is mainly distributed in the ground such as the Abazangzuqiangzu Autonomous Prefecture of western Sichuan, Tibetan Autonomous Prefecture of Garze, Yaan, Xichang, Yi Autonomous Prefecture of Liangshan and Eastern Tibet.Radix Vladimiriae root is containing volatile oil, and main component has constuslactone, dehydrocostuslactone, wears constuslactone, eugenol and sesquiterpenoids composition, wears constuslactone content maximum, is about 1%.Radix Vladimiriae has inhibitory action to staphylococcus aureus, dysentery bacterium and bacillus pyocyaneus, also inhibitory action is had to dermatophytes, effective ingredient in Radix Vladimiriae volatile oil has good bactericidal action, especially to some pathomycetes as trichophyton interdigitale, toes trichophyton, Epidermophvton tinea, trichophyton, homocentricity endodermophyton, the little sporeformer of rust, the little sporeformer of dog, permitted blue achorion, permitted the mutation of blue achorion Mongolia and have inhibitory action, effectively can suppress tinea pedis, degerming anti-smelly.
Herba Pogostemonis is the dry aerial parts of Labiatae thorn stamen grass platymiscium Herba Pogostemonis, is distributed in the provinces and regions such as Guangdong, Hainan, Guangxi, Taiwan and Yunnan more.Herba Pogostemonis is containing volatile oil, triterpene saponin, chromocor compound, sterol etc.Radix agastaches extract can suppress superficial part dermatophytes as the growth and breeding of trichophyton, the little sporeformer of dog and acrothesium floccosum etc. completely, also there is anti-skin bacterium active, also have stronger inhibitory action to staphylococcus aureus, micrococcus luteus, escherichia coli, mycete, bacillus subtilis and Hansenula yeast bacterium.Radix agastaches extract has wide spectrum and strong suppression to fungus, can be used for preventing and treating the dermatopathies such as tinea pedis, can effective bacteriostasis, and deodorization to foot.
Adeps Bovis seu Bubali is Labiatae origanum, is commonly called as Origanum majorana L., hyssop, Yunnan Herba Moslae, Herba Origani, Herba Ziziphorae clinopodioidis, is mainly distributed in the ground such as Henan, Shaanxi, Gansu.The compound such as volatile oil, triterpene saponin, sterol, tannin, flavone and flavonoid glycoside, coumarin, phenolic acid is had in Adeps Bovis seu Bubali.Methanthiol and ammonia are that human body mainly causes smelly composition, Adeps Bovis seu Bubali extract has inhibitory action to methioninase activity, the content of methanthiol in body odor can be reduced, the content of ammonia in body odor can be reduced to the inhibitory action of xanthine oxidase activity, Adeps Bovis seu Bubali extract has strong antibiotic property, can effectively press down smelly.
Radix Oenotherae erythrosepalae is Oenotheraceae Oenothera plant, and popular name Radix Helicteris, Radix Oenotherae erythrosepalae, be mainly distributed in the ground such as China Guizhou, Shandong, Henan, northeast.Radix Oenotherae erythrosepalae extract has inhibitory action to methioninase and ornithine enzymatic activity equally, can suppress the generation of methanthiol and reduce ammonia to generate, can effectively deodorization.
The following Components Name that the application occurs is INCI (International NomenclaureCosmetic Ingredient, i.e. international cosmetic raw material name) title of defined, such as: propylene glycol/diazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate etc.
To sum up, the advantage of bacteriostasis, and deodorization cosmetic composition of the present invention is as follows:
Compared with prior art, four kinds of natural plant extracts Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution add in bacteriostasis, and deodorization cosmetic composition by the present invention, natural gentleness, Synergistic, stable system, as the foot bacteriostatic deodorant cosmetics that a class is new, can killing fungus, read the various skin tinea bacterium such as coccus, mycete, antibacterial, effective bacteriostasis, and deodorization.In addition, bacteriostasis, and deodorization cosmetic composition of the present invention directly can be applied in foot, forms bacteriostasis, and deodorization layer, kills dermatophytosis, and can ensure that foot sweat gland is normal, easy to use.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme is described further.
The preparation of Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution:
The Radix Vladimiriae of drying being joined mass ratio is in the ethanol of 85%, under backflow and dipping, carry out extraction 6h.Subsequently, with filter cloth, extracting solution is filtered, then under rotating speed 3000r/min, centrifugalize 30 minutes, namely obtains Radix Vladimiriae extracting solution.
The Herba Pogostemonis of drying being joined mass ratio is in the ethanol of 85%, under backflow and dipping, carry out extraction 6h.Subsequently, with filter cloth, extracting solution is filtered, then under rotating speed 3000r/min, centrifugalize 30 minutes, namely obtains Herba Pogostemonis extracting solution.
The Adeps Bovis seu Bubali of drying being joined mass ratio is in the ethanol of 85%, under backflow and dipping, carry out extraction 6h.Subsequently, with filter cloth, extracting solution is filtered, then under rotating speed 3000r/min, centrifugalize 30 minutes, namely obtains Adeps Bovis seu Bubali extracting solution.
The Radix Oenotherae erythrosepalae of drying being joined mass ratio is in the ethanol of 85%, under backflow and dipping, carry out extraction 6h.Subsequently, with filter cloth, extracting solution is filtered, then under rotating speed 3000r/min, centrifugalize 30 minutes, namely obtains Radix Oenotherae erythrosepalae extracting solution.
The formula of the bacteriostasis, and deodorization cosmetic composition of embodiment 1-3 and comparative example 1-3 is in table 1.
Table 1
The formula of the bacteriostasis, and deodorization cosmetic composition of embodiment 4-6 and comparative example 4-6 is in table 2.
Table 2
The formula of the bacteriostasis, and deodorization cosmetic composition of embodiment 7-9 and comparative example 7-9 is in table 3.
Table 3
The formula of the bacteriostasis, and deodorization cosmetic composition of embodiment 10-12 and comparative example 10-12 is in table 4.
Table 4
The cosmetic composition of above-described embodiment 1-12 and comparative example 1-12 is obtained by following preparation method:
(1) wetting agent, thickening agent mixing is scattered, add water, be heated to 80 ~ 90 DEG C, 4000 revs/min after homogenizing 5-10 minute, constant temperature 85 DEG C, 50 revs/min are stirred after 30-40 minute and start cooling;
(2) be cooled to 50-55 DEG C, add antiinflammatory, stir;
(3) be cooled to 40-45 DEG C, add nertralizer, stir;
(4) add plant extraction liquid and antiseptic, stir, obtain bacteriostasis, and deodorization cosmetic composition.
Embodiment 13 overall efficacy evaluates clinical experiment
The cosmetics that above-described embodiment 1-12 and comparative example 1-12 is obtained, respectively through the serious experimenter of 100 20 ~ 50 years old beriberi situations 28 days on probation continuously, foot bacteriostatic deodorizing effect and the sweat gland perspiration situation of cosmetics obtained in the various embodiments described above are evaluated in relative analysis.Wherein, described foot bacteriostatic deodorizing effect is the improvement situation of foot odor, foot pruritus, toe erythema, foot's blister, foot's decortication etc., the results are shown in Table 5.
Table 5
The cosmetic composition of above-described embodiment 1-12 and comparative example 1-12 does not all find zest and allergic phenomena in process on probation.
As known from Table 5: the product foot of embodiment and comparative example uses rear sweat gland perspiration situation all normal, in embodiment, the improvement degree of each product to foot odor, foot pruritus, toe erythema, foot's blister, foot's decortication etc. is obviously high than the improvement degree of product each in comparative example, and Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, the parts by weight of the mixed liquor of Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution are larger, foot odor, foot pruritus, toe erythema, foot's blister, the improvement degree of foot's decortication is higher, at Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, the mixed liquor weight portion of Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution is 10 ~ 30 parts, Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, the weight part ratio of Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution is (2 ~ 10): (2 ~ 10): (2 ~ 10): time (2 ~ 10), the cost performance of product is the highest.
The antibacterial sterilizing test of embodiment 14
The protective system efficiency evaluation method that this experiment is recommended with reference to Americanized cosmetic, toilet articles and essence association (CTFA), the sterilizing single challenge experiment of 28 days by a definite date of the classics recommended with CTFA.
1. challenge microorganism: dermatophytosis (comprising fungus, candidiasis, mycete, antibacterial)
2. the mode inoculated and quantity
(1) mode inoculated: adopt combined inoculation.Because natural microorganism has mixed raw feature of living together, so the situation of the realistic pollution of combined inoculation.
(2) quantity inoculated: by each strain inoculation in suitable culture medium, cultivates in 28 DEG C (funguses), 36 DEG C (candidiasis), 28 DEG C (mycete), 37 DEG C of (antibacterial) incubators.Fungus, candidiasis, mycotic culture 72 hours, antibacterial culturing, after 48 hours, is selected typical bacterium colony in the fluid medium of sterilizing, is made certain density fungus, candidiasis, mycete, antibacterial mixing suspension, be placed in refrigerator cold-storage for subsequent use.Fungus, candidiasis, every gram, mycete suspension bacteria containing amount are 1 × 10
5cFU/g or CFU/ml; Every gram, antibacterial suspension bacteria containing amount is 1 × 10
6cFU/g or CFU/ml.
3. Microbial Challenge experiment
Take each 100 grams of embodiment 1 ~ 12 cosmetic sample, add in the container of sterilizing, add mixed fungus, candidiasis, mycete, bacterial suspension, fully mix.Every gram of sample is 1 × 10 containing fungus, candidiasis, mycete amount
5cFU/g or CFU/ml; Amount of bacteria is 1 × 10
6cFU/g or CFU/ml, at being then placed in 28 DEG C.Connecing 0,7,14,21,28 day sample analysis of bacterium: accurately take 10 grams of samples, be added in the conical flask containing glass pellet and 90ml sterile saline, abundant concussion mixing, this suspension is 1:10 diluent, and then dilutes successively by 1:10 with normal saline.Cultivate 72 hours at cultivation 72 hours, 28 DEG C, mycete at cultivation 72 hours, candidiasis 36 DEG C at fungus 28 DEG C, cultivate 48 hours at 37 DEG C, antibacterial, by bacteria containing amount in dull and stereotyped tilt-pour process count samples.
4. evaluation methodology
Fungus, candidiasis, mycete or antibacterial is contained at 10CFU/g ~ 100CFU/g (CFU/ml) in 28 days samples, but show that this sample has dermatophytosis and stronger kill effect, by challenge test, dropped to below 1000CFU/g (CFU/m1) at the 7th day to be considered as passing through, other is considered as not passing through.
5. experimental result
Inoculation 0,7,14,2l and 28 day sampling detects, the antibacterial sterilizing test result of embodiment 1 ~ 12 cosmetic combinations matter sample is in table 6.
Table 6
As known from Table 6: each cosmetic composition of embodiment 1 ~ 12 has certain bacteriostasis and sterilization effect, and Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, the parts by weight of the mixed liquor of Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution are larger, antibacterial sterilization effect is better, at Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, the mixed liquor weight portion of Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution is 10 ~ 30 parts, Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, the weight part ratio of Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution is (2 ~ 10): (2 ~ 10): (2 ~ 10): time (2 ~ 10), the cost performance of product is the highest.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (7)
1. a bacteriostasis, and deodorization cosmetic composition, is characterized in that, comprises each component of following parts by weight:
Wherein, described plant extraction liquid is the mixed liquor of Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution.
2. bacteriostasis, and deodorization cosmetic composition according to claim 1, it is characterized in that, the weight portion of described plant extraction liquid is 10 ~ 30 parts; The weight part ratio of described Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution is (0.5 ~ 10): (0.5 ~ 10): (0.5 ~ 10): (0.5 ~ 10).
3. bacteriostasis, and deodorization cosmetic composition according to claim 1 or 2, it is characterized in that, the weight part ratio of described Radix Vladimiriae extracting solution, Herba Pogostemonis extracting solution, Adeps Bovis seu Bubali extracting solution and Radix Oenotherae erythrosepalae extracting solution is (2 ~ 10): (2 ~ 10): (2 ~ 10): (2 ~ 10).
4. bacteriostasis, and deodorization cosmetic composition according to any one of claim 1-3, is characterized in that, described thickening agent is carbomer; Described nertralizer is triethanolamine; Described antiseptic is propylene glycol/diazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate.
5. bacteriostasis, and deodorization cosmetic composition according to any one of claim 1-3, it is characterized in that, described wetting agent is weight part ratio is (5 ~ 10): (3 ~ 5): the mixing of the glycerol of (0.01 ~ 0.03), propylene glycol, hyaluronate sodium.
6. bacteriostasis, and deodorization cosmetic composition according to any one of claim 1-3, is characterized in that, described antiinflammatory is weight part ratio is (0.05 ~ 0.1): the allantoin of (0.05 ~ 0.1) and the mixing of Flos Inulae extract.
7. a preparation method for bacteriostasis, and deodorization cosmetic composition described in any one of claim 1-6, is characterized in that, comprise the following steps:
(1) wetting agent, thickening agent mixing is scattered, add water, be heated to 80 ~ 90 DEG C, 4000 revs/min after homogenizing 5-10 minute, constant temperature 85 DEG C, 50 revs/min are stirred after 30-40 minute and start cooling;
(2) be cooled to 50-55 DEG C, add antiinflammatory, stir;
(3) be cooled to 40-45 DEG C, add nertralizer, stir;
(4) add plant extraction liquid and antiseptic, stir, obtain bacteriostasis, and deodorization cosmetic composition.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105076246A (en) * | 2015-08-28 | 2015-11-25 | 无限极（中国）有限公司 | Antibacterial traditional Chinese medicine composition, preparing method of antibacterial traditional Chinese medicine composition and application of antibacterial traditional Chinese medicine composition |
| CN105640830A (en) * | 2016-01-15 | 2016-06-08 | 李国超 | Marine natural antibacterial composition and application thereof |
| CN105687020A (en) * | 2016-01-20 | 2016-06-22 | 广州丹奇日用化工厂有限公司 | Foot powder for preventing feet from chapping |
-
2014
- 2014-12-24 CN CN201410821737.XA patent/CN104586682A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 王建新: "《化妆品植物原料手册》", 30 June 2009 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105076246A (en) * | 2015-08-28 | 2015-11-25 | 无限极（中国）有限公司 | Antibacterial traditional Chinese medicine composition, preparing method of antibacterial traditional Chinese medicine composition and application of antibacterial traditional Chinese medicine composition |
| CN105640830A (en) * | 2016-01-15 | 2016-06-08 | 李国超 | Marine natural antibacterial composition and application thereof |
| CN105687020A (en) * | 2016-01-20 | 2016-06-22 | 广州丹奇日用化工厂有限公司 | Foot powder for preventing feet from chapping |
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Application publication date: 20150506 |