CN105250195A - Plant compound preservative and acne removal skincare product - Google Patents
Plant compound preservative and acne removal skincare product Download PDFInfo
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- CN105250195A CN105250195A CN201510660332.7A CN201510660332A CN105250195A CN 105250195 A CN105250195 A CN 105250195A CN 201510660332 A CN201510660332 A CN 201510660332A CN 105250195 A CN105250195 A CN 105250195A
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61Q19/10—Washing or bathing preparations
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Abstract
The invention discloses a plant compound preservative. The plant compound preservative is prepared from, by weight, 1-20 parts of a plant root extractive, 1-20 parts of a plant flower extractive, 10-30 parts of a plant leaf extractive and 1-10 parts of plant bark extractive. The plant root extractive is obtained by mixing and extracting 1-5 parts of scutellaria baicalensis, 0.1-1 part of radix sophorae flavescentis, 0.1-1 part of moss, 1-5 parts of cordate houttuynia and 1-5 parts of Chinese herbaceous peony. The plant flower extractive is obtained by mixing and extracting 5-10 parts of calendula, 1-10 parts of hibiscus mutabilis and 1-10 parts of honeysuckle. The plant leaf extractive is obtained by mixing and extracting 1-10 parts of lotus leaves, 5-10 parts of ginkgo leaves, 2-5 parts of rosemary leaves, 1-5 parts of olive leaves and 5-10 parts of perilla leaves. The plant bark extractive is obtained by mixing and extracting 5-10 parts of shaddock peel and 1-5 parts of cinnamon. The invention further discloses an acne removal skincare product containing the plant compound preservative. The plant compound preservative can effectively inhibit growth of microorganisms such as germs and fungi in skincare product, can prolong the service life of the skincare product and has the advantages of being free of toxicity or simulation or skin sensibility or the like.
Description
Technical field
The present invention relates to household chemicals field, particularly the control oil anti-acne skin care item of a kind of plant Compositional antiseptic agent and this plant Compositional antiseptic agent of use.
Background technology
Skin care item generally all can add antiseptic, be mainly used in killing and suppress the microorganism in skin care item, long-time maintenance skin care item quality, antiseptic is mainly by acting on cell membrane, multiple target spot such as cell wall and enzyme of microorganism, destroy the division of cell, bacteria growing inhibiting and breeding, reach antiseptical object.Because the microbe species causing skin care item putrid and deteriorated is various, and the minimal inhibitory concentration of single antiseptic and scope of restraining fungi have certain restriction, therefore, in order to more effectively prevent skin care item putrid and deteriorated and secondary pollution before the deadline, Compositional antiseptic agent is applied in skin care item more and more widely.What current most of skin care item company used is all chemosynthesis antiseptic, and chemosynthesis antiseptic all exists zest is large, toxicity is large defect, safety aspect is not very satisfactory.
Summary of the invention
In order to overcome the shortcoming of prior art, the invention provides a kind of natural plants Compositional antiseptic agent, it effectively can suppress the microbial growth such as antibacterial, fungus in skin care item, extends skin care item useful lifes, and have nontoxic, non-stimulated, without advantages such as skin allergy.Present invention also offers a kind of anti-acne skin care item adding this plant Compositional antiseptic agent.
The present invention is achieved in that a kind of plant Compositional antiseptic agent, be made up of the following each component with weight portion: plant roots extract 1 ~ 20 part, Plant flawer extracts 1 ~ 20 part, leaves of plants extract 10 ~ 30 parts and plant peel extract 1 ~ 10 part, described plant roots extract is by Radix Scutellariae 1 ~ 5 part, Radix Sophorae Flavescentis 0.1 ~ 1 part, 0.1 ~ 1 part, moss, Herba Houttuyniae 1 ~ 5 part and Radix Paeoniae 1 ~ 5 part of mixed extraction obtain, described Plant flawer extracts is by Flos Inulae 5 ~ 10 parts, Flos Hibisci Mutabilis 1 ~ 10 part and Flos Lonicerae 1 ~ 10 part of mixed extraction obtain, described leaves of plants extract is by 1 ~ 10 part, Folium Nelumbinis, Folium Ginkgo 5 ~ 10 parts, leaf of Herba Rosmarini Officinalis 2 ~ 5 parts, 1 ~ 5 part, Folium olive and Folium Perillae 5 ~ 10 parts of mixed extraction obtain, described plant peel extract is obtained by pomelo peel 5 ~ 10 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) 1 ~ 5 part of mixed extraction.
Peony Root contains peoniflorin, benzoic acid isoreactivity composition, and peoniflorin has blood vessel dilating, comparatively broad-spectrum antiseptic and antiinflammation, and benzoic acid has antibacterial, antioxidative effect, and can also have certain therapeutical effect to mottle by blood circulation promoting and blood stasis dispelling, has white-skinned face function; In scutellariae,radix, main active has baicalin and baicalin, and wherein baicalin and baicalin etc. have stronger inhibitory action to pathogen such as staphylococcus aureus, Staphylococcus albus, bacillus subtilis, escherichia coli; Radix Sophorae Flavescentis contains number of chemical composition and has biological activity widely, based on antibacterial, arrhythmia, it all has significant inhibitory action to dysentery bacterium, gold-coloured staphylococci, dimension Hakuri Salmonella, also has inhibitory action in various degree to ten various skin funguses such as a beautiful gem color trichophytons; The effective ingredient decanoylacetaldehyde etc. of Herba Houttuyniae has bacteriostasis, and houttuynine sodium bisulfite, to micrococcus catarrhalis, staphylococcus aureus, hemophilus influenza, streptococcus pneumoniae and Hemolytic streptococcus etc., has obvious inhibitory action; To escherichia coli, dysentery bacterium, bacillus pyocyaneus, Bacillus proteus, diphtheria corynebacterium and mycobacteria, there is certain inhibitory action; To Bacillus typhi and leptospira, also there is stronger inhibitory action; Flos Inulae has antibacterial, antiinflammation, particularly better to staphylococcus, streptococcus effect; Containing the Flavonoid substances such as the organic acid such as chlorogenic acid, isochlorogenic acid and luteolin, luteolin-7-O-α-D glucoside, luteolin-7-O-β-D galactoside, quercetin-3-O-β-D glucoside in Flos Lonicerae, these active substances have very strong anti-inflammation effect and antioxidation; Containing phenols and tannin isoreactivity composition in leaf of Herba Rosmarini Officinalis, there is broad-spectrum antibacterial effect; Flos Hibisci Mutabilis, except having antibacterial effect, also has white-skinned face function; Containing alkaloids such as nuciferine, N-nornuciferine, the nor-nuciferine of O-, reticulines in Folium Nelumbinis, they have strong antimitotic effect, thus have stronger bacteriostasis; Containing flavone, lactone and ginkgoic acid in Folium Ginkgo, wherein ginkgoic acid is 6-alkyl or the salicylic derivant of 6-thiazolinyl, multiple fungus and bacterium can be suppressed, better to the inhibition of the anaerobe such as Streptococcus mutans, also there is the activity suppressing hyaluronidase and tryrosinase simultaneously, have effect of skin whitening, meanwhile, Folium Ginkgo also has good anti-oxidation efficacy; Folium olive, except having antibacterial effect, also has very strong free radical resisting effect; Containing physiologically active ingredients such as alkaloids, flavonoid, terpenoid in pomelo peel, wherein, flavone compound has the effects such as antioxidation, antiallergic, anti-inflammation, slow down aging.Pomelo peel has obvious inhibition to E.coli and yeast; The main active of Cortex cinnamomi japonici (Ramulus Cinnamomi) has cinnamic aldehyde, and it is antifungal active substance, mainly by destroying fungal cell wall, making medicine infiltrate in fungal cell, destroys organelle and play bacteriostasis.
This plant Compositional antiseptic agent application in skin care item, it can be applicable to the skin care item preparing the cosmetics exterior-applied formulations such as anti-acne facial cleanser, anti-acne Cleansing Foam, Pimple removing scream, Whelk-eliminating paste, acne eliminating cream, anti-acne emulsion, anti-acne astringent, Deacne pack, blemish clearing gel or anti-acne soap.
The present invention has following beneficial effect: the present invention screens root, flower, the pure natural plant such as leaf and skin of various plants, and extract its active component and make natural, green plant Compositional antiseptic agent, this antiseptic effectively can suppress the microbial growth such as middle antibacterial, fungus in skin care item, antiseptic effect is close to chemical preservative, but the defect that the zest overcoming chemical preservative is large, toxicity is large, nontoxic to human-body safety, also there is the advantages such as antioxidation, whitening and antiinflammatory.Meanwhile, this product has wide material sources, processes the advantages such as cheap, effectively can reduce production cost, improves product competitiveness in the market.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be described in detail, and embodiment is only the preferred embodiment of the present invention, is not limitation of the invention.
Embodiment 1
One kind of plant Compositional antiseptic agent, be made up of the following each component with weight portion: plant roots extract 5 parts, Plant flawer extracts 15 parts, leaves of plants extract 15 parts and plant peel extract 10 parts, described plant roots extract is obtained by Radix Scutellariae 1 part, Radix Sophorae Flavescentis 0.1 part, 1 part, moss, Herba Houttuyniae 3 parts and Radix Paeoniae 5 parts of mixed extraction, described Plant flawer extracts is obtained by Flos Inulae 5 parts, Flos Hibisci Mutabilis 10 parts and Flos Lonicerae 1 part of mixed extraction, and described leaves of plants extract is obtained by 1 part, Folium Nelumbinis, Folium Ginkgo 10 parts, 1 part, Folium olive, Folium Perillae 10 parts and leaf of Herba Rosmarini Officinalis 5 parts of mixed extraction; Described plant peel extract is obtained by pomelo peel 5 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) 5 parts of mixed extraction.
Described plant roots extract is obtained by following methods: finishing collecting Radix Scutellariae, Radix Sophorae Flavescentis, moss, Herba Houttuyniae and Radix Paeoniae are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 64%, liquid material mass ratio is 25:1, soak 3h, historrhexis is carried out 4 times with the rotating speed of 10000r/min, each 8 minutes, then leave standstill 3 hours, obtain mixed liquor; Then pour in countercurrent extraction machine and extract, obtain coarse filtration liquid; With membrane filtration, obtain preliminary filtrate; Concentrate with reverse osmosis membrane at normal temperatures, obtain the first concentrated solution of solid contents 15%; Get the vacuum concentration that half first concentrated solution carries out at 35 DEG C, obtain the second concentrated solution of solid content 35%; By dry after the first remaining concentrated solution and the mixing of the second concentrated solution, to obtain final product;
Described Plant flawer extracts is obtained by following methods: finishing collecting Flos Hibisci Mutabilis, Flos Inulae and Flos Lonicerae are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 52%, liquid material mass ratio is 12:1, soak 3h, historrhexis is carried out 2 times with the rotating speed of 5000r/min, each 5 minutes, then leave standstill 3 hours, obtain mixed liquor; Then pour in countercurrent extraction machine and extract, obtain coarse filtration liquid; With membrane filtration, obtain preliminary filtrate; Concentrate with reverse osmosis membrane at normal temperatures, obtain the first concentrated solution of solid contents 5%; Get the vacuum concentration that half first concentrated solution carries out at 35 DEG C, obtain the second concentrated solution of solid content 15%; By dry after the first remaining concentrated solution and the mixing of the second concentrated solution, to obtain final product;
Described leaves of plants extract is obtained by following methods: finishing collecting Folium Nelumbinis, Folium Ginkgo, leaf of Herba Rosmarini Officinalis, Folium olive and Folium Perillae are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 58%, liquid material mass ratio is 20:1, soak 3h, historrhexis is carried out 3 times with the rotating speed of 8000r/min, each 8 minutes, then leave standstill 3 hours, obtain mixed liquor; Then pour in countercurrent extraction machine and extract, obtain coarse filtration liquid; With membrane filtration, obtain preliminary filtrate; Concentrate with reverse osmosis membrane at normal temperatures, obtain the first concentrated solution of solid contents 15%; Get the vacuum concentration that half first concentrated solution carries out at 35 DEG C, obtain the second concentrated solution of solid content 28%; By dry after the first remaining concentrated solution and the mixing of the second concentrated solution, to obtain final product;
Described plant peel extract is obtained by following methods: finishing collecting pomelo peel and Cortex cinnamomi japonici (Ramulus Cinnamomi) are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 55%, liquid material mass ratio is 10:1, soak 3h, historrhexis is carried out 3 times with the rotating speed of 5000r/min, each 8 minutes, then leave standstill 3 hours, obtain mixed liquor; Then pour in countercurrent extraction machine and extract, obtain coarse filtration liquid; With membrane filtration, obtain preliminary filtrate; Concentrate with reverse osmosis membrane at normal temperatures, obtain the first concentrated solution of solid contents 8%; Get the vacuum concentration that half first concentrated solution carries out at 35 DEG C, obtain the second concentrated solution of solid content 20%; By dry after the first remaining concentrated solution and the mixing of the second concentrated solution, to obtain final product.
One kind of plant Compositional antiseptic agent obtains by the following method: plant roots extract, Plant flawer extracts, leaves of plants extract and plant peel extract Homogeneous phase mixing are obtained by above-mentioned parts by weight.
Embodiment 2
One kind of plant Compositional antiseptic agent, be made up of the following each component with weight portion: plant roots extract 18 parts, Plant flawer extracts 10 parts, leaves of plants extract 10 parts and plant peel extract 6 parts, described plant roots extract is obtained by Radix Scutellariae 3 parts, Radix Sophorae Flavescentis 0.6 part, 0.1 part, moss, Herba Houttuyniae 5 parts and Radix Paeoniae 1 part of mixed extraction, described Plant flawer extracts is obtained by Flos Inulae 8 parts, Flos Hibisci Mutabilis 5 parts and Flos Lonicerae 10 parts of mixed extraction, and described leaves of plants extract is obtained by 7 parts, Folium Nelumbinis, Folium Ginkgo 8 parts, 5 parts, Folium olive, Folium Perillae 8 parts and leaf of Herba Rosmarini Officinalis 4 parts of mixed extraction; Described plant peel extract is obtained by pomelo peel 8 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) 3 parts of mixed extraction.
Plant roots, plant flowers, leaves of plants and the extract of plant peel and the preparation method of plant Compositional antiseptic agent consistent with embodiment 1.
Embodiment 3
One kind of plant Compositional antiseptic agent, be made up of the following each component with weight portion: plant roots extract 12 parts, Plant flawer extracts 6 parts, leaves of plants extract 25 parts and plant peel extract 2 parts, described plant roots extract is obtained by Radix Scutellariae 5 parts, Radix Sophorae Flavescentis 1 part, 0.5 part, moss, Herba Houttuyniae 1 part and Radix Paeoniae 2 parts of mixed extraction, described Plant flawer extracts is obtained by Flos Inulae 10 parts, Flos Hibisci Mutabilis 1 part and Flos Lonicerae 5 parts of mixed extraction, and described leaves of plants extract is obtained by 10 parts, Folium Nelumbinis, Folium Ginkgo 5 parts, 2 parts, Folium olive, Folium Perillae 5 parts and leaf of Herba Rosmarini Officinalis 2 parts of mixed extraction; Described plant peel extract is obtained by pomelo peel 10 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) 1 part of mixed extraction.
Plant roots, plant flowers, leaves of plants and the extract of plant peel and the preparation method of plant Compositional antiseptic agent consistent with embodiment 1.
Comparative example 1
One kind of plant Compositional antiseptic agent, be made up of the following each component with weight portion: plant roots extract 12 parts, leaves of plants extract 25 parts, described plant roots extract is obtained by Radix Scutellariae 5 parts, Radix Sophorae Flavescentis 1 part, 0.5 part, moss, Herba Houttuyniae 1 part and Radix Paeoniae 2 parts of mixed extraction, and described leaves of plants extract is obtained by 10 parts, Folium Nelumbinis, Folium Ginkgo 5 parts, 2 parts, Folium olive, Folium Perillae 5 parts and leaf of Herba Rosmarini Officinalis 2 parts of mixed extraction.
The extract of plant roots, leaves of plants and the preparation method of plant Compositional antiseptic agent consistent with embodiment 1.
Comparative example 2
One kind of plant Compositional antiseptic agent, be made up of the following each component with weight portion: Plant flawer extracts 15 parts and plant peel extract 10 parts, described Plant flawer extracts is obtained by Flos Inulae 5 parts, Flos Hibisci Mutabilis 10 parts and Flos Lonicerae 1 part of mixed extraction, and described plant peel extract is obtained by pomelo peel 5 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) 5 parts of mixed extraction.
Plant flowers and the extract of plant peel and the preparation method of plant Compositional antiseptic agent consistent with embodiment 1.
The invention provides a kind of acne-removing composition, be made up of the following each component with weight portion: 5 ~ 10 parts, oil suction powder, fresh aloe juice 75 ~ 85 parts, Lac regis apis extract 3 ~ 8 parts, Radix Salviae Miltiorrhizae extract 2 ~ 10 parts, Radix Glycyrrhizae extract 1 ~ 5 part, sugared Thallus Laminariae (Thallus Eckloniae) extract 1 ~ 5 part, flower of Fructus Mali pumilae extract 1 ~ 5 part, allantoin 1 ~ 5 part.This acne-removing composition can be used as the skin care item preparing the cosmetics exterior-applied formulations such as anti-acne facial cleanser, anti-acne Cleansing Foam, Pimple removing scream, Whelk-eliminating paste, acne eliminating cream, anti-acne emulsion, anti-acne astringent, Deacne pack, blemish clearing gel or anti-acne soap; Before preparing various skin care item, by the weight portion of each component, oil suction powder, Lac regis apis extract, Radix Salviae Miltiorrhizae extract, Radix Glycyrrhizae extract, sugared Thallus Laminariae (Thallus Eckloniae) extract, flower of Fructus Mali pumilae extract and allantoin are added to fresh aloe juice in advance, mix homogeneously (preferably microwave vacuum process after mixing) obtains acne-removing composition.
The fungistatic effect of the antiseptic of each embodiment and comparative example, stability and zest evaluation methodology and result
1, fungistatic effect
1) preparation of sample solution: after each antiseptic water dissolution, being made into mass concentration is that the sample solution of 0.1g/mL is for subsequent use.
2) actication of culture
Get test tube some, after loading the medium sterilization melted, be put into inclined-plane.Aseptically will move on the corresponding slant medium of access for examination strain by method of scoring, put into incubator, antibacterial culturing 24h at 37 DEG C, mycete cultivates 48 ~ 72h at 28 DEG C.
3) preparation of strains tested suspension
Picking a small amount of lawn from the fresh strain inclined plane after each activation is inoculated in respective liquid culture medium, respectively at cultivating in 37 DEG C, 28 DEG C constant-temperature shaking incubators as original bacteria liquid after 24h, 48-72h, making containing bacterium number with sterile saline by each original bacteria liquid is respectively the bacteria suspension of 106 ~ 108CFU/mL.
4) fungistatic effect measures
20mL sterilising medium is poured into sterile petri dish system dull and stereotyped, inject above-mentioned 1 × 106CFU/mL bacteria suspension 100 μ L after cooling, smear with aseptic rod and be expanded to media surface.Then put aseptic Oxford cup thereon equidistantly, in cup, inject the different sample solutions of 200 μ l respectively, make synchronous bacteriostatic experiment and carry out blank.Put into incubator, antibacterial cultivates 48h at 37 DEG C, cultivates 48 ~ 72h at 28 DEG C, mycete.Take out on time, measure antibacterial circle diameter, get its meansigma methods.
More than work and all complete on superclean bench.
5) experimental result
Fungistatic effect experiment is shown in Table 1.
The fungistatic effect of table 1 embodiment 1 to 3 and comparative example 1,2
2, stability and zest
Plant Compositional antiseptic agent is used in a kind of Deacne pack skin care item, this facial film is made up of the following each component with weight portion: polyvinyl alcohol 8 parts, glycerol 7 parts, hydrolyzed-silk glue protein 1 part, ethanol 8 parts, C11-15 alkanol polyethers-7 carboxylic acid sodium 9 parts, acne-removing composition 42 parts, plant Compositional antiseptic agent 0.4 part, deionized water 24.98 parts, wherein said acne-removing composition is made up of the following each component with weight portion: 8 parts, oil suction powder, fresh aloe juice 82 parts, Lac regis apis extract 5 parts, Radix Salviae Miltiorrhizae extract 8 parts, Radix Glycyrrhizae extract 3 parts, sugar Thallus Laminariae (Thallus Eckloniae) extract 2 parts, flower of Fructus Mali pumilae extract 1 part and allantoin 3 parts.The preparation method of this Deacne pack, comprise the following steps: polyvinyl alcohol is added in deionized water, be heated to 85 DEG C, dissolve, be cooled to 45 DEG C, add glycerol, hydrolyzed-silk glue protein, ethanol, the stirring of C11-15 alkanol polyethers-7 carboxylic acid sodium, be cooled to less than 40 DEG C, add acne-removing composition and plant Compositional antiseptic agent, stir, can Deacne pack be obtained.
Stability: evaluate stability in each temperature observations stability over 1 month, concrete outcome is in table 2.
Stability under table 2 embodiment 1 to 3 different temperatures
| Embodiment 1 | Embodiment 2 | Embodiment 3 | |
| Room temperature | Stable | Stable | Stable |
| 4℃ | Stable | Stable | Stable |
| 37℃ | Stable | Stable | Stable |
| 45℃ | Stable | Stable | Stable |
| Circulation | Stable | Stable | Stable |
Zest: a certain amount of different tested material is put into speckle examination device, spread on the Medial upper arm of experimenter's (selecting 20 ~ 40 years old N/R healthy men and women of skin as study subject), continue 48 hours; Zest is confirmed according to erythema degree and to the enquirement of experimenter.
Detailed method is as follows:
Smearing method: closedpatchtest(Medial upper arm);
Applying amount: 20ul ~ 30ul/chamber;
Smear number of times and time limit: stick 24 hours, observe 24 hours after sticking test.
Observing response: observe according to the term (terminology) of CTFA criterion after patch test 30 points and 24 hours, result is as follows:
The dermoreaction of embodiment 1 to 3 is small erythema, and adopt mixing methyl parahydroxybenzoate 0.2 part, nipasol 0.1 part and imidazolidinyl urea 0.1 part of dermoreaction as antiseptic to be that strong erythema is to edema, illustrate that this plant Compositional antiseptic agent is almost non-stimulated to skin, but methyl hydroxybenzoate, nipasol, stimulation confirmed as by the antiseptic of imidazolidinyl urea composition.
Embodiment 4 one kinds of blemish clearing gel skin care item
A kind of blemish clearing gel skin care item, are made up of the following each component with weight portion: acne-removing composition 48 parts, acrylic acid dimethyltaurine ammonium/VP copolymer 2 parts, butanediol 6 parts, propylene glycol 10 parts, the vegetable preservative 0.4 part of embodiment 1, deionized water 33.6 parts; Described acne-removing composition is made up of the following each component with weight portion: 10 parts, oil suction powder, fresh aloe juice 75 parts, Lac regis apis extract 8 parts, Radix Salviae Miltiorrhizae extract 10 parts, Radix Glycyrrhizae extract 5 parts, sugared Thallus Laminariae (Thallus Eckloniae) extract 1 part, flower of Fructus Mali pumilae extract 1 part and allantoin 5 parts.The preparation method of this blemish clearing gel, comprises the following steps: butanediol, vegetable preservative, deionized water mix and blend are dissolved; Add acrylic acid dimethyltaurine ammonium/VP copolymer, limit edged stirs, and stir to obtain transparent colloid substrate; Added by acne-removing composition in propylene glycol, stir to obtain solution; Again by gelatinous matrix and solution mixing and stirring, then add residue deionized water; Regulate pH value to 6, inspection, canned.
Embodiment 5 one kinds of acne eliminating cream skin care item
A kind of acne eliminating cream skin care item, are made up of the following each component with weight portion: thioctic acid 0.005 part, glyceryl stearate 4 parts, fine jade wax stereth 4 parts, vitamin e1 part, vitamin A 0.5 part, 5 parts, olive oil, myristic acid isopropyl ester 5 parts, 804 parts, polysorbate fat, polyglycerolmethacrylate 8 parts, acne-removing composition 30 parts, glycerol 4 parts, carbomer 0.3 part, the vegetable preservative 0.25 part of embodiment 2, deionized water 39.945 parts; Described acne-removing composition is made up of the following each component with weight portion: 7 parts, oil suction powder, fresh aloe juice 80 parts, Lac regis apis extract 6 parts, Radix Salviae Miltiorrhizae extract 7 parts, Radix Glycyrrhizae extract 3 parts, sugared Thallus Laminariae (Thallus Eckloniae) extract 3 parts, flower of Fructus Mali pumilae extract 3 parts and allantoin 2 parts.The preparation method of this acne eliminating cream, comprises the following steps: by vegetable preservative, glycerol, carbomer, deionized water, polyglycerolmethacrylate, stir, be heated to 86 DEG C for subsequent use; By acne-removing composition, thioctic acid, glyceryl stearate, fine jade wax stereth, vitamin E, vitamin A, olive oil, isopropyl myristate, polysorbate80, be heated to 86 DEG C, slowly add aqueous phase, homogenizing 3500 revs/min, be cooled to 50 DEG C, add essence, stir, 35 DEG C of dischargings.
Embodiment 6 one kinds of Deacne pack skin care item
A kind of Deacne pack skin care item, are made up of the following each component with weight portion: polyvinyl alcohol 8 parts, glycerol 7 parts, hydrolyzed-silk glue protein 1 part, ethanol 8 parts, C11-15 alkanol polyethers-7 carboxylic acid sodium 9 parts, acne-removing composition 42 parts, the vegetable preservative 0.3 part of embodiment 3, deionized water 24.7 parts; Described acne-removing composition is made up of the following each component with weight portion: 8 parts, oil suction powder, fresh aloe juice 82 parts, Lac regis apis extract 5 parts, Radix Salviae Miltiorrhizae extract 8 parts, Radix Glycyrrhizae extract 3 parts, sugared Thallus Laminariae (Thallus Eckloniae) extract 2 parts, flower of Fructus Mali pumilae extract 1 part and allantoin 3 parts.The preparation method of this Deacne pack, comprise the following steps: polyvinyl alcohol is added in deionized water, be heated to 85 DEG C, dissolve, be cooled to 45 DEG C, add glycerol, hydrolyzed-silk glue protein, ethanol, the stirring of C11-15 alkanol polyethers-7 carboxylic acid sodium, be cooled to less than 40 DEG C, add acne-removing composition and vegetable preservative, stir, can Deacne pack be obtained.
Embodiment 7 one kinds of anti-acne facial cleanser skin care item
A kind of anti-acne facial cleanser skin care item, are made up of the following each component with weight portion: acne-removing composition 38 parts, Herba Lysimachiae foenum-graeci quintessence oil 5 parts, 6 parts, olive oil, Oleum Cocois 6 parts, the vegetable preservative 0.4 part of embodiment 2, deionized water 44.6 parts; Described acne-removing composition is made up of the following each component with weight portion: 5 parts, oil suction powder, fresh aloe juice 85 parts, Lac regis apis extract 3 parts, Radix Salviae Miltiorrhizae extract 2 parts, Radix Glycyrrhizae extract 1 part, sugared Thallus Laminariae (Thallus Eckloniae) extract 5 parts, flower of Fructus Mali pumilae extract 1 part and allantoin 5 parts.The preparation method of this anti-acne facial cleanser, comprises the following steps: Herba Lysimachiae foenum-graeci quintessence oil, olive oil, Oleum Cocois are mixed homogeneously with deionized water, then filters after acne-removing composition being added mixing, and filtrate is bottled stand-by after sterilization.
Embodiment 8 one kinds of anti-acne astringent skin care item
A kind of anti-acne astringent skin care item, are made up of the following each component with weight portion: acne-removing composition 25 parts, thioctic acid 0.4 part, the vegetable preservative 0.2 part of embodiment 2, propylene glycol 5,807 parts, polysorbate fat, 0.2 part, essence, deionized water 62.2 parts; Described acne-removing composition is made up of the following each component with weight portion: 7 parts, oil suction powder, fresh aloe juice 80 parts, Lac regis apis extract 6 parts, Radix Salviae Miltiorrhizae extract 7 parts, Radix Glycyrrhizae extract 3 parts, sugared Thallus Laminariae (Thallus Eckloniae) extract 3 parts, flower of Fructus Mali pumilae extract 3 parts and allantoin 2 parts.The preparation method of this anti-acne astringent, comprises the following steps: by acne-removing composition, thioctic acid, vegetable preservative, propylene glycol, polysorbate80, and heating makes dissolving, adds essence, under agitation slowly adds in deionized water, be stirred to homogeneous transparent.
Embodiment 9 one kinds of anti-acne astringent skin care item
A kind of anti-acne astringent skin care item, are made up of the following each component with weight portion: acne-removing composition 25 parts, thioctic acid 0.4 part, the vegetable preservative 0.2 part of comparative example 2, propylene glycol 5,807 parts, polysorbate fat, 0.2 part, essence, deionized water 62.2 parts; Described acne-removing composition is made up of the following each component with weight portion: 7 parts, oil suction powder, fresh aloe juice 80 parts, Lac regis apis extract 6 parts, Radix Salviae Miltiorrhizae extract 7 parts, Radix Glycyrrhizae extract 3 parts, sugared Thallus Laminariae (Thallus Eckloniae) extract 3 parts, flower of Fructus Mali pumilae extract 3 parts and allantoin 2 parts.The preparation method of this anti-acne astringent, comprises the following steps: by acne-removing composition, thioctic acid, vegetable preservative, propylene glycol, polysorbate80, and heating makes dissolving, adds essence, under agitation slowly adds in deionized water, be stirred to homogeneous transparent.
Comparative example 3
A kind of anti-acne astringent skin care item, are made up of the following each component with weight portion: acne-removing composition 25 parts, thioctic acid 0.4 part, chemical preservative 0.3 part, propylene glycol 5,807 parts, polysorbate fat, 0.2 part, essence, deionized water 62.1 parts; Described acne-removing composition is made up of the following each component with weight portion: 7 parts, oil suction powder, fresh aloe juice 80 parts, Lac regis apis extract 6 parts, Radix Salviae Miltiorrhizae extract 7 parts, Radix Glycyrrhizae extract 3 parts, sugared Thallus Laminariae (Thallus Eckloniae) extract 3 parts, flower of Fructus Mali pumilae extract 3 parts and allantoin 2 parts.The preparation method of this anti-acne astringent, comprises the following steps: by acne-removing composition, thioctic acid, chemical preservative, propylene glycol, polysorbate80, and heating makes dissolving, adds essence, under agitation slowly adds in deionized water, be stirred to homogeneous transparent.
Comparative example 4
A kind of anti-acne astringent skin care item, are made up of the following each component with weight portion: acne-removing composition 25 parts, thioctic acid 0.4 part, propylene glycol 5,807 parts, polysorbate fat, 0.2 part, essence, deionized water 62.4 parts; Described acne-removing composition is made up of the following each component with weight portion: 7 parts, oil suction powder, fresh aloe juice 80 parts, Lac regis apis extract 6 parts, Radix Salviae Miltiorrhizae extract 7 parts, Radix Glycyrrhizae extract 3 parts, sugared Thallus Laminariae (Thallus Eckloniae) extract 3 parts, flower of Fructus Mali pumilae extract 3 parts and allantoin 2 parts.The preparation method of this anti-acne astringent, comprises the following steps: by acne-removing composition, thioctic acid, propylene glycol, polysorbate80, and heating makes dissolving, adds essence, under agitation slowly adds in deionized water, be stirred to homogeneous transparent.
Fresh aloe juice is obtained by following methods: select organic Aloe Barbadensis Miller fresh leaf (fresh leaf of U.S.'s Curacao, trophophase more than 2 years, pollution-free disease-free) as raw material, after cleaning, sterilizing, remove end to end, trimming peeling, grind process, one-step method process that the Aloe gel after grinding is taked " stabilisation and sterilizing ", then be cooled to less than 40 DEG C rapidly with liquid nitrogen, then be aseptically separated by gravy, obtain the fresh juice of organic aloe.Wherein stabilisation sterilization treatment refers to by adding 0.23% citric acid and 0.085%EDTA-2Na in the Aloe gel after grinding respectively as acidulant, chelating agen, by heat treatment (85 DEG C), passivation is carried out to the enzyme in Aloe gel, to realize Aloe gel stabilisation sterilization treatment.In addition, in processing procedure, any enzyme should not be added.
It is a kind of ω-hydroxy acid be present in nature Lac regis apis that Lac regis apis extract contains 10-hydroxydecanoic acid, decanedioic acid, decanediol and 10-HDA, 10-HDA, and the Lac regis apis extract in the present invention is the AcnacidolBG purchased from ISP company.
Radix Salviae Miltiorrhizae extract is obtained by following methods: get salvia piece, adds 10 times of water gagings of Radix Salviae Miltiorrhizae dry weight, under reduced pressure, 75 DEG C of extractions 3 times of seething with excitement, each 2.5h, merge extractive liquid, filter, less than 60 DEG C concentrating under reduced pressure, are concentrated into the clear paste that relative density is 1.2, clear paste is 190 DEG C in spray dryer inlet temperature, and outlet temperature is 80 DEG C, under moisture less than 8% condition, carry out spraying dry, the granule that spraying dry obtains is pulverized, and crosses 80 mesh sieves, obtains Radix Salviae Miltiorrhizae extract.Radix Salviae Miltiorrhizae extract has the functions such as promoting blood flow to regulate menstruation, promoting tissue regeneration by removing blood stasis, tranquillizing and allaying excitement, removing heat from blood eliminating carbuncle, reducing swelling and alleviating pain.In Radix Salviae Miltiorrhizae, active component TANSHINONES has antibacterial action, extremely sensitive to Propiobacterium, and be a kind of estrogen-like product of mitigation, play anti-androgen effect, also there is the antiinflammatory action of similar hydrocortisone simultaneously, strong to gram-positive bacteria antibacterial action, obviously can reduce propionibacterium acnes counting, and can suppress acute and react with subacute inflammation, there is antiinflammatory action.Still have gentle estrogenic activity and anti-in acid andrusol effect, anti-androgenic effect and the effect of anti-sebum glandular secretion definite.Gonadal hormone especially androgen has close relationship with the generation of acne, development, persistent state.TANSHINONES avoids application estrin treatment acne usually, and the shortcoming of interference patient body intracellular metabolite, improves the clinical symptoms of acne from many aspects. and subject range is wider.In addition, the blood circulation promoting and blood stasis dispelling function that TANSHINONES has still raised path between farm fields improves the blood circulation of face, promotes the metabolism of affected skin.
Radix Glycyrrhizae extract is obtained by following methods: according to 1:5 weight ratio, drops into ethanol and carries out extracting, filtering, obtain extracting solution in Radix Glycyrrhizae; Extracting solution is concentrated, makes the concentration ratio of extracting solution simmer down to 30 Brix degree; Add distilled water according to the ratio of 1:2 in extracting solution after above-mentioned concentrating, the extracting solution after concentrated is washed; Extracting solution after washing carries out concentrating under reduced pressure again; Extracting solution after concentrated is carried out drying, obtains Radix Glycyrrhizae extract.Radix Glycyrrhizae has the anti-aging effect of whitening antiinflammatory.
Sugar Thallus Laminariae (Thallus Eckloniae) extract is brown algae extract; Preferably purchased from Féraud stamen gold and/or the Féraud stamen gold BG of MarineBiotech, France, can also be that the product being HG657 from the product designation of Ennagram, France company obtains.Sugar Thallus Laminariae (Thallus Eckloniae) extract can regulation of skin fat secretion well, significantly improves sebum overflow, suppresses the inflammation that lipolytic enzyme causes, rebuild skin physiology balance.
Flower of Fructus Mali pumilae extract is Flos Rosae Rugosae, apple flower and Flos Inulae mixed extract, and wherein the part by weight of Flos Rosae Rugosae, apple flower and Flos Inulae is 1:3:1.5.Flos Inulae has gentle maintenance, Sage Extract, makes skin water tender moist; Calm skin, improves sensitivity skin quality; The effects such as the anti-pox of pore refining, antiallergic, blood circulation promoting.Flos Rosae Rugosae has that Huoxue San " is stagnant, removing toxic substances and promoting subsidence of swelling, can eliminate the disease such as facial skin sore, pigmentation caused because of endocrine dysfunction; Apple flower mouthfeel is unique, have enrich blood or alleviate neuralgia, improving eyesight of enriching blood, pox-eliminating whitening effect.This flower of Fructus Mali pumilae extract is obtained by following methods: finishing collecting Flos Rosae Rugosae, apple flower and Flos Inulae are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 65%, carry out historrhexis 5 times with the rotating speed of 10000r/min, each 10 minutes, then leave standstill 3 hours, obtain mixed liquor; With membrane filtration, obtain feed liquid; Feed liquid is positioned in distillator and distills, obtain concentrate; Concentrate is placed in oil water separator and is separated, obtain flower of Fructus Mali pumilae extract.
Described oil suction powder is the mixture of starch ocentyl succinic aluminum, acrylic copolymer, magnesium carbonate composition, and wherein the part by weight of starch ocentyl succinic aluminum, acrylic copolymer, magnesium carbonate is 3:2:1.This oil suction powder is the modified starch of a oil absorption, and oil absorption is outstanding, energy deep layer cleaning skin, the oils and fats piled up in sucking-off pore and dirt.
Microorganism level detects: undertaken canned by the skin care item dark brown vial that embodiment 4 to 8 and comparative example 4,5 obtain respectively, open wide bottle cap, under being placed in the environment of ambient temperature 40 DEG C, relative humidity 85%, continuous observation is also tested, and concrete outcome sees the following form; Test item, detection method and examination criteria carry out according to QB/T2872-2007.
| Observe phenomena | |
| Embodiment 4 | No abnormality seen after 60 days, pure in smell |
| Embodiment 5 | No abnormality seen after 60 days, pure in smell |
| Embodiment 6 | No abnormality seen after 60 days, pure in smell |
| Embodiment 7 | No abnormality seen after 60 days, pure in smell |
| Embodiment 8 | No abnormality seen after 60 days, pure in smell |
| Embodiment 9 | After 45 days, occur mildew, microorganism exceeds standard, and distributes unhappy abnormal smells from the patient |
| Comparative example 3 | No abnormality seen after 60 days, pure in smell |
| Comparative example 4 | After 5 days, occur mildew, microorganism exceeds standard, and distributes unhappy abnormal smells from the patient |
The above embodiment only have expressed embodiments of the present invention; it describes comparatively concrete and detailed; but therefore can not be interpreted as the restriction to the scope of the claims of the present invention; in every case the technical scheme adopting the form of equivalent replacement or equivalent transformation to obtain, all should drop within protection scope of the present invention.
Claims (7)
1. a kind of plant Compositional antiseptic agent, be made up of the following each component with weight portion: plant roots extract 1 ~ 20 part, Plant flawer extracts 1 ~ 20 part, leaves of plants extract 10 ~ 30 parts and plant peel extract 1 ~ 10 part, described plant roots extract is by Radix Scutellariae 1 ~ 5 part, Radix Sophorae Flavescentis 0.1 ~ 1 part, 0.1 ~ 1 part, moss, Herba Houttuyniae 1 ~ 5 part and Radix Paeoniae 1 ~ 5 part of mixed extraction obtain, described Plant flawer extracts is by Flos Inulae 5 ~ 10 parts, Flos Hibisci Mutabilis 1 ~ 10 part and Flos Lonicerae 1 ~ 10 part of mixed extraction obtain, described leaves of plants extract is by 1 ~ 10 part, Folium Nelumbinis, Folium Ginkgo 5 ~ 10 parts, leaf of Herba Rosmarini Officinalis 2 ~ 5 parts, 1 ~ 5 part, Folium olive and Folium Perillae 5 ~ 10 parts of mixed extraction obtain, described plant peel extract is obtained by pomelo peel 5 ~ 10 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi) 1 ~ 5 part of mixed extraction.
2. plant Compositional antiseptic agent according to claim 1, it is characterized in that, described plant roots extract is obtained by following methods: finishing collecting Radix Scutellariae, Radix Sophorae Flavescentis, moss, Herba Houttuyniae and Radix Paeoniae are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 64%, liquid material mass ratio is 25:1, soaks 3h, historrhexis is carried out 4 times with the rotating speed of 10000r/min, each 8 minutes, then leave standstill 3 hours, obtain mixed liquor; Then pour in countercurrent extraction machine and extract, obtain coarse filtration liquid; With membrane filtration, obtain preliminary filtrate; Concentrate with reverse osmosis membrane at normal temperatures, obtain the first concentrated solution of solid contents 15%; Get the vacuum concentration that half first concentrated solution carries out at 35 DEG C, obtain the second concentrated solution of solid content 35%; By dry after the first remaining concentrated solution and the mixing of the second concentrated solution, to obtain final product;
Described Plant flawer extracts is obtained by following methods: finishing collecting Flos Hibisci Mutabilis, Flos Inulae and Flos Lonicerae are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 52%, liquid material mass ratio is 12:1, soak 3h, historrhexis is carried out 2 times with the rotating speed of 5000r/min, each 5 minutes, then leave standstill 3 hours, obtain mixed liquor; Then pour in countercurrent extraction machine and extract, obtain coarse filtration liquid; With membrane filtration, obtain preliminary filtrate; Concentrate with reverse osmosis membrane at normal temperatures, obtain the first concentrated solution of solid contents 5%; Get the vacuum concentration that half first concentrated solution carries out at 35 DEG C, obtain the second concentrated solution of solid content 15%; By dry after the first remaining concentrated solution and the mixing of the second concentrated solution, to obtain final product;
Described leaves of plants extract is obtained by following methods: finishing collecting Folium Nelumbinis, Folium Ginkgo, leaf of Herba Rosmarini Officinalis, Folium olive and Folium Perillae are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 58%, liquid material mass ratio is 20:1, soak 3h, historrhexis is carried out 3 times with the rotating speed of 8000r/min, each 8 minutes, then leave standstill 3 hours, obtain mixed liquor; Then pour in countercurrent extraction machine and extract, obtain coarse filtration liquid; With membrane filtration, obtain preliminary filtrate; Concentrate with reverse osmosis membrane at normal temperatures, obtain the first concentrated solution of solid contents 15%; Get the vacuum concentration that half first concentrated solution carries out at 35 DEG C, obtain the second concentrated solution of solid content 28%; By dry after the first remaining concentrated solution and the mixing of the second concentrated solution, to obtain final product;
Described plant peel extract is obtained by following methods: finishing collecting pomelo peel and Cortex cinnamomi japonici (Ramulus Cinnamomi) are positioned in pulverizer cylinder body, add the ethanol mixing that concentration is 55%, liquid material mass ratio is 10:1, soak 3h, historrhexis is carried out 3 times with the rotating speed of 5000r/min, each 8 minutes, then leave standstill 3 hours, obtain mixed liquor; Then pour in countercurrent extraction machine and extract, obtain coarse filtration liquid; With membrane filtration, obtain preliminary filtrate; Concentrate with reverse osmosis membrane at normal temperatures, obtain the first concentrated solution of solid contents 8%; Get the vacuum concentration that half first concentrated solution carries out at 35 DEG C, obtain the second concentrated solution of solid content 20%; By dry after the first remaining concentrated solution and the mixing of the second concentrated solution, to obtain final product.
3. blemish clearing gel skin care item, be made up of the following each component with weight portion: oils and fats 20 ~ 25 parts, wetting agent 1 ~ 5 part, emulsifying agent 1 ~ 3 part, chelating agen 0.1 ~ 0.5 part, plant Compositional antiseptic agent 0.01 ~ 0.05 part, spice 0.1 ~ 0.5 part, acne-removing composition 50 ~ 60 parts as claimed in claim 1, surplus is deionized water, complements to 100 parts; Wherein, described acne-removing composition is made up of the following each component with weight portion: 5 ~ 10 parts, oil suction powder, fresh aloe juice 75 ~ 85 parts, Lac regis apis extract 3 ~ 8 parts, Radix Salviae Miltiorrhizae extract 2 ~ 10 parts, Radix Glycyrrhizae extract 1 ~ 5 part, sugared Thallus Laminariae (Thallus Eckloniae) extract 1 ~ 5 part, flower of Fructus Mali pumilae extract 1 ~ 5 part, allantoin 1 ~ 5 part.
4. acne eliminating cream skin care item, be made up of the following each component with weight portion: thioctic acid 0.001 ~ 0.005 part, glyceryl stearate 1 ~ 5 part, fine jade wax stereth 1 ~ 5 part, vitamin e1 ~ 5 part, vitamin A 0.1 ~ 0.5 part, 1 ~ 5 part, olive oil, myristic acid isopropyl ester 1 ~ 5 part, 801 ~ 5 parts, polysorbate fat, polyglycerolmethacrylate 5 ~ 10 parts, acne-removing composition 30 ~ 40 parts, glycerol 1 ~ 5 part, carbomer 0.1 ~ 0.3 part, plant Compositional antiseptic agent 0.1 ~ 0.3 part as claimed in claim 1, surplus is deionized water, complements to 100 parts; Wherein, described acne-removing composition is made up of the following each component with weight portion: 5 ~ 10 parts, oil suction powder, fresh aloe juice 75 ~ 85 parts, Lac regis apis extract 3 ~ 8 parts, Radix Salviae Miltiorrhizae extract 2 ~ 10 parts, Radix Glycyrrhizae extract 1 ~ 5 part, sugared Thallus Laminariae (Thallus Eckloniae) extract 1 ~ 5 part, flower of Fructus Mali pumilae extract 1 ~ 5 part, allantoin 1 ~ 5 part.
5. Deacne pack skin care item, be made up of the following each component with weight portion: polyvinyl alcohol 5 ~ 10 parts, glycerol 5 ~ 10 parts, hydrolyzed-silk glue protein 1 ~ 3 part, ethanol 5 ~ 10 parts, C11-15 alkanol polyethers-7 carboxylic acid sodium 5 ~ 10 parts, acne-removing composition 40 ~ 45 parts, plant Compositional antiseptic agent 0.01 ~ 0.03 part as claimed in claim 1, surplus is deionized water, complements to 100 parts; Wherein, described acne-removing composition is made up of the following each component with weight portion: 5 ~ 10 parts, oil suction powder, fresh aloe juice 75 ~ 85 parts, Lac regis apis extract 3 ~ 8 parts, Radix Salviae Miltiorrhizae extract 2 ~ 10 parts, Radix Glycyrrhizae extract 1 ~ 5 part, sugared Thallus Laminariae (Thallus Eckloniae) extract 1 ~ 5 part, flower of Fructus Mali pumilae extract 1 ~ 5 part, allantoin 1 ~ 5 part.
6. anti-acne facial cleanser skin care item, be made up of the following each component with weight portion: acne-removing composition 35 ~ 40 parts, Herba Lysimachiae foenum-graeci quintessence oil 5 ~ 10 parts, 5 ~ 10 parts, olive oil, Oleum Cocois 5 ~ 10 parts, plant Compositional antiseptic agent 0.01 ~ 0.03 part as claimed in claim 1, surplus is deionized water, complements to 100 parts; Wherein, described acne-removing composition is made up of the following each component with weight portion: 5 ~ 10 parts, oil suction powder, fresh aloe juice 75 ~ 85 parts, Lac regis apis extract 3 ~ 8 parts, Radix Salviae Miltiorrhizae extract 2 ~ 10 parts, Radix Glycyrrhizae extract 1 ~ 5 part, sugared Thallus Laminariae (Thallus Eckloniae) extract 1 ~ 5 part, flower of Fructus Mali pumilae extract 1 ~ 5 part, allantoin 1 ~ 5 part.
7. anti-acne astringent skin care item, be made up of the following each component with weight portion: acne-removing composition 20 ~ 30 parts, thioctic acid 0.1 ~ 0.5 part, plant Compositional antiseptic agent 0.1 ~ 0.3 part, propylene glycol 1 ~ 5,805 ~ 10 parts, polysorbate fat, 0.1 ~ 0.5 part, essence as claimed in claim 1, surplus is deionized water, complements to 100 parts; Wherein, described acne-removing composition is made up of the following each component with weight portion: 5 ~ 10 parts, oil suction powder, fresh aloe juice 75 ~ 85 parts, Lac regis apis extract 3 ~ 8 parts, Radix Salviae Miltiorrhizae extract 2 ~ 10 parts, Radix Glycyrrhizae extract 1 ~ 5 part, sugared Thallus Laminariae (Thallus Eckloniae) extract 1 ~ 5 part, flower of Fructus Mali pumilae extract 1 ~ 5 part, allantoin 1 ~ 5 part.
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| CN107308064A (en) * | 2017-08-08 | 2017-11-03 | 广州蜜妆生物科技有限公司 | A kind of compound natural preservative |
| CN107375056A (en) * | 2017-06-21 | 2017-11-24 | 佛山实瑞先导材料研究院（普通合伙） | A kind of preservative and its application |
| CN109730946A (en) * | 2019-03-09 | 2019-05-10 | 广州市壹美和生物科技有限公司 | Active acne-eliminating liquid and lotion, Essence and face cream containing active acne-eliminating liquid |
| CN112137929A (en) * | 2020-10-10 | 2020-12-29 | 昆山市双友日用化工有限公司 | Novel cosmetic antiseptic composition |
| CN112545938A (en) * | 2020-12-15 | 2021-03-26 | 上海应用技术大学 | Preparation method and application of apple flower extract |
| CN113304072A (en) * | 2021-05-26 | 2021-08-27 | 建昌帮药业有限公司 | Floral water |
| CN113456570A (en) * | 2021-07-23 | 2021-10-01 | 完美（广东）日用品有限公司 | Acne-removing composition, acne-removing gel and preparation method thereof |
| CN114129481A (en) * | 2021-12-08 | 2022-03-04 | 上海纳米技术及应用国家工程研究中心有限公司 | Acne removing essence and preparation method thereof |
| CN115804738A (en) * | 2022-03-30 | 2023-03-17 | 广东格烯生物科技股份有限公司 | Plant acne-removing composition containing radix sophorae flavescentis and salvia miltiorrhiza and preparation method thereof |
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| CN107375056A (en) * | 2017-06-21 | 2017-11-24 | 佛山实瑞先导材料研究院（普通合伙） | A kind of preservative and its application |
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| CN115804738B (en) * | 2022-03-30 | 2024-06-11 | 广东格烯生物科技股份有限公司 | Plant acne-removing composition containing radix sophorae flavescentis and radix salviae miltiorrhizae and preparation method thereof |
| CN116869888A (en) * | 2023-08-03 | 2023-10-13 | 清远市望莎生物科技有限公司 | Natural plant preservative composition with antibacterial effect and preparation and application thereof |
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Application publication date: 20160120 |