KR101432996B1 - CLEANSING COMPOSITION COMPRISING NATURAL COMPOUNDS EXTRACT OF Oenanthe javanica DC, Artemisia capillaris and Artemisiae capillaris Flos COMPLEX FOR LADIES, ITS METHOD TO USE AND PROCESS THEREOF - Google Patents

Abstract

The present invention provides a female detergent composition prepared by extracting 5 to 15 parts by weight of a natural raw material with 100 parts by weight of a polar solvent selected from the group consisting of water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof, 80% by weight, 18 to 35% by weight of arum japonica, and 2 to 8% by weight of Artemisia officinalis.
The composition according to the present invention is harmless to the human body because there is no fear of contact with chemicals because only the substance extracted from the edible raw material is used as an effective ingredient. It can also help to clean female genitalia by effectively eliminating various harmful bacteria including fungi inside female vagina. Especially, it is effective for suppressing cold, low blood pressure, female genital odor and female genital pruritus induced bacteria, thereby suppressing cold, high fever and pruritus of female genitalia or eliminating odor.

Description

TECHNICAL FIELD [0001] The present invention relates to a female detergent composition comprising a natural raw material extract of a plant of the genus Nematoda, an artificial insect worm, and an Artemisia capillaris, a method of using the same, AND PROCESS THEREOF}

The present invention relates to a female cleaner composition and a method of making the same. Specifically, the present invention relates to a female cleanser composition having a characteristic of effectively preventing female genital pruritus and cold or cold of female genital warts by blending chrysanthemum worms and flowers thereof, and a method for preparing the same.

The pollution of the vagina which threatens the health of women (due to various bacteria, such as molds) can cause various female diseases and infertility. 75% of women experience more than once in their lifetime and 45% of women experience more than twice a year, which is very serious. Although commercially available medical products for feminine cleaning are on the market, most of the materials used in the vagina are products of chemical compositions containing iodine and the like. Although povidone-iodine is known to be effective in the treatment of Candida albicans or Trichomonas vaginitis and other vaginal infections, it may cause burning sensation, ulcers, contact dermatitis due to hypersensitivity symptoms or mucosal damage such as iodine, May lead to hypothyroidism.

However, even in the case of antimicrobial agents derived from natural materials, development of antifungal agents satisfying these requirements is still required when considering the residual, economical aspect, and antimicrobial activity of pesticides.

Under these circumstances, the present inventors have found that a composition comprising an active ingredient obtained by drying, aging, extracting, filtering, and sterilizing a flower of the genus Syringa, Artemisia mugwort or Artemisia capillaris is useful for pathogenic microorganisms and other vaginal microorganisms Confirming that it exhibits antimicrobial activity, it is confirmed that it does not cause the safety problem of the chemical female cleaner, and the present invention has been completed.

The object of the present invention is to solve the above-mentioned problems, and it is an object of the present invention to provide a female cleanser A method of using the same, and a manufacturing method.

The present invention provides a female detergent composition prepared by extracting 5 to 15 parts by weight of a natural raw material with 100 parts by weight of a polar solvent selected from the group consisting of water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof, 80% by weight, 18 to 35% by weight of arginine and 2 to 8% by weight of arthropod flowers.

Also, the present invention provides a method of using a female cleaner composition prepared by extracting 5 to 15 parts by weight of a natural raw material with 100 parts by weight of a polar solvent selected from the group consisting of water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof, The natural raw material is composed of 60 to 80% by weight of Porphyra, 18 to 35% by weight of Artemisia japonica, and 2 to 8% by weight of Artemisia japonica, and is used for washing female reproductive organs by diluting a female cleaner composition and water at a ratio of 1: 2 to 1: .

The present invention also provides a method for preparing a female detergent composition prepared by extracting 5 to 15 parts by weight of a natural raw material with 100 parts by weight of a polar solvent selected from the group consisting of water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof, The natural raw material comprises 60 to 80% by weight of Porphyra, 18 to 35% by weight of Artemisia sp. And 2 to 8% by weight of Artemisia sp.

1) naturally drying the natural raw material for 3 months,

2) ripping dried natural raw materials and aging at room temperature for 2 ~ 3 years,

3) extracting 5 to 15 parts by weight of the aged natural raw material with 100 parts by weight of a polar solvent selected from the group consisting of water, a lower alcohol having 1 to 4 carbon atoms, or a mixed solvent thereof;

4) filtering the extract,

5) sterilizing the filtrate at a temperature of 90 ° C or more and 100 ° C or less.

Since the female cleaner composition according to the present invention uses only the substance extracted from the edible raw material as an active ingredient, there is no fear of contact with the chemical, which is harmless in the human body. It can also help to clean female genitalia by effectively eliminating various harmful bacteria including fungi inside female vagina. Especially, it is effective for suppressing cold, low blood pressure, female genital odor and female genital pruritus induced bacteria, thereby suppressing cold, low fever and pruritus of female genitalia or eliminating odor.

FIG. 1 shows the antibacterial effect of Bacillus megaterium on the concentration of the female cleaner composition according to the present invention.
Figure 2 shows the antimicrobial effect of Candida albicans on the concentration of the female detergent composition according to the present invention.
Am means ampicillin, and Ka means kanamycin, respectively.

The present invention relates to a female detergent composition prepared by extracting 1 to 15 parts by weight, preferably 5 to 10 parts by weight of a natural raw material with 100 parts by weight of a polar solvent selected from the group consisting of water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof , And the natural raw materials are a combination of Porphyry, Artemisia and Artemisia flowers.

In the female detergent composition of the present invention, the natural raw material is composed of 10 to 80% by weight of Porphyra, 18 to 45% by weight of Artemisia japonica and 2 to 18% by weight of Artemisia officinalis, preferably 60 to 80% By weight and 2 to 8% by weight of Artemisia officinalis.

It is also known as a field of buttercups, and it has been used for the purpose of eating juice by grinding, which can not be used for edible food because it grows in the banks of rivers and deep mountains. In particular, it contains potassium, calcium, vitamin C, carotene and vegetable fiber, which are converted into vitamin A in the body, and contains SOD, a kind of chlorophyll and antioxidant enzyme. In addition, the essential oils and essences of the unique flavor and flavor of the haremari not only stimulates the taste, but also cleanses the mind and has the effect of cleansing the blood.

The mugwort is a medicinal mugwort that is known to be the most effective mugwort ever. It is a plant of Asteraceae which grows up to 1.8m straight like a tree and has various pharmacological actions. According to various oriental medical literature including Dongbokbo, it is said that it has a 100 kinds of effects including liver disease such as jaundice by warming the body and passing it through the meridian, and it is indispensable to control various kinds of women's diseases such as cold, It is described as a medicinal product.

The Artemisia japonica flower refers to a flower blooming before and after the harvest time of Artemisia japonica. As with all plants, it is presumed that they will contain various nutrients and effective ingredients as flowers during the flowering process and making fruit and seeds for breeding, but the specific pharmacological effects have not been revealed to date.

The natural raw material constituting the present invention is preferably aged for 1 to 3 years, preferably 2 to 3 years. Less than one year of active ingredient may be less, and aging of more than three years is not economically desirable.

The female cleansing composition of the present invention can be formulated into a liquid preparation such as a solvent, a suspension, an emulsion, a tincture, a syrup, a spray or an extract.

The present invention provides a female detergent composition characterized in that it has an effect on female genital candidiasis.

The present invention also provides a female cleanser composition characterized by alleviating female genital organs and odors.

The female cleaner composition according to the present invention can be diluted with water to 1: 2 to 10, preferably 1: 2 to 1: 8, and more preferably 1: 4. If the ratio of the female cleaner composition to the water is 1: 8 or more, it may be ineffective. If the ratio is less than 1: 2, it may feel irritating to the site of use.

As a further aspect of the present invention, there is provided a method for manufacturing a female cleaner composition.

The manufacturing method includes: 1) drying the natural raw material; 2) aging; 3) extracting; 4) filtering; and 5) sterilizing.

1) Dry for 3 months.

2) Aging is carried out at room temperature for 2 ~ 3 years by cutting the dried natural raw material.

3) Extraction is carried out in a mixed solvent having 100 parts by weight of water, a lower alcohol having 1 to 4 carbon atoms or a mixing ratio (kg / l) thereof of about 10: 1 to 1:10, preferably 1: 1 to 1: 3 5 to 15 parts by weight, preferably 8 to 10 parts by weight, of the aged natural raw material is heated at 90 to 100 占 폚, preferably 95 占 폚 for 10 to 24 hours.

4) Filtration is carried out using filter.

5) Sterilization is performed by heating the filtrate at 90 ~ 100 ℃.

The term " natural raw material "

Hereinafter, the present invention will be described in more detail with reference to the following examples. However, the following examples are intended to illustrate the present invention, but the scope of the present invention is not limited thereto.

Example

Manufacturing example  One

Organic cultivation, Organic cultivation, 3 years Drying 25kg and Artemisia spp. (Organic cultivation, Organic cultivation, 3 years drying) 70kg, Aging) and 1400 kg of purified water were boiled in a cauldron and concentrated to a total weight of 1450 kg to prepare an extract. The extract was filtered through a flooded cartridge filter (10 microns), and the filtrate was pasteurized at 95 ° C to obtain a female cleaner composition according to the present invention.

Manufacturing example  2

A total of 10 samples were prepared (diluted to 1: 512) by preparing a sample of the female cleansing composition obtained according to Preparation Example 1, which was diluted by 1/2 from the undiluted solution with distilled water.

Example  1: Antimicrobial activity test

Ten samples obtained according to Preparation Example 2 were subjected to an antimicrobial activity test using the paper disc agar diffusion method.

Bacillus megaterium (KCTC 3007, available from Korean Microorganism Conservation Center) and Candida albicans (KCTC 1940, available from Korean Microorganism Conservation Center) were used as test strains.

Bacillus megaterium was cultured in LB medium (Luria-Bertani medium consisting of tryptone, sodium chloride and yeast extract) and Candida albicans in YPD medium (medium consisting of yeast extract, peptone and dextrose) (37 ° C and 30 ° C, respectively) for 24 hours. When the OD value was 1, 1 ml of the culture was inoculated into a solid LB medium supplemented with 1.0% agar, and 10 samples prepared in Preparation Example 2 The filter paper discs (10 mm in diameter) were absorbed in a sterilized filter paper disc (20 μl each), and then placed on a plate medium to adhere them. After culturing for 24 hours, the antimicrobial activity of the sample was confirmed by the size (mm ² ) of the growth inhibition ring around the disk. The antimicrobial effect of kanamycin (50 μg / ml) and ampicillin (100 μg / ml) was compared using the same method as above.

The experimental results are shown in FIGS. 1 and 2.

As shown in FIGS. 1 and 2, the composition of the present invention exhibited antibacterial activity against Bacillus megaterium and candida albicans in a 1: 2 to 1: 4 dilution with a female detergent composition stock solution and water.

Claims (7)

The present invention relates to a female detergent composition comprising, as a natural raw material, dried, cut and packaged, aged at room temperature for 1 to 3 years,
100 parts by weight of a polar solvent selected from the group consisting of water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof is mixed with a natural raw material 5 composed of 60 to 80% by weight of umbilicus, 18 to 35% by weight of arum japonica and 2 to 8% ≪ / RTI > to 15 parts by weight of the composition. delete delete delete delete A female genital detergent comprising 1: 2 to 1: 4 the female cleansing composition according to claim 1 and water. delete

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