KR101694707B1 - Deodorant composition comprising the extract of Abeliophyllum distichum Nakai distichum - Google Patents

Abstract

The present invention relates to a deodorant composition containing a hydroxycarboxylic acid extract which can be used as a natural deodorant for improving noneleral deodorization by using a hydroxycarboxylic acid extract having a deodorizing effect extracted from Abeliophyllum distichum, It is possible to realize a non-deodorant by providing a composition containing an extract of Helicobidae extracted with ethanol as an effective ingredient.

Description

A deodorant composition containing an extract of Abelmoschus niger extract (Abelophyllum distichum Nakai distichum)

In particular, the present invention relates to a deodorant composition containing a herbal extract. In particular, the present invention relates to a deodorant composition containing a natural deodorant for the improvement of a non-deodorant by using a herbal extract having a deodorant effect extracted from Abeliophyllum distichum, To a deodorant composition containing a barberry extract.

Reduces a wide variety of odors such as smell formed during processing and preservation of food, odor from old people, hospital, beauty salon, office, clothes, smell of sweat, smell of tobacco, kitchen smell, exploitation of building materials, And deodorizing and deodorizing agents are used to remove them. Generally, commercially available deodorization deodorants are mainly oriented aromatic masking agents, and many kinds of deodorants such as toilet, household, automobile air freshener, business use for various business sites are sold. Examples of these forms include evaporation by volatilization and sublimation of an oily component solidified by aerosol, spraying, gelatin, agar, etc. by an inert gas such as Freon, evaporation from the surface of the powder, silica, etc., One adsorption type and so on.

The deodorization technique using a fragrance can be divided into a masking method and a neutralization function. The masking method is a method of reversing the odor in the direction, and paralyzing a human's smell with the smell of perfume to thereby eliminate discoloration and discomfort (wood vinegar, Benzene, etc.). The masking method of concealing odor as an odor-intensive fragrance can be easily understood by considering the fragrance, lotion, cream, and the like, which is a deodorant widely used today to control the body odor by the method that has been used since ancient times by mankind. They all control the odor without chemical changes, and when deodorant is used at a high concentration, it can be harmful to the human body.

In general, sebaceous glands in the human skin secrete sebum to the skin surface through the pores to prevent water evaporation and maintain skin elasticity. However, when the discharged sebum is brought into contact with air on the skin surface, the microorganisms existing on the skin propagate, thereby oxidizing the sebum to produce a bad body odor.

The main cause of the smell of the elderly is aging, but the human body that consumes, digests and excretes the food for decades has not metabolized smoothly, and the waste matter is made much, and the unsaturated fatty acid decomposes and the nonenaldehyde (C ₉ H ₁₆ O) When it does, it smells bad. Especially sweat glands, armpits, around the penis, glands and other places where the sweeps do not dry well and do not leave the smell of a rustle.

As society becomes increasingly nuclear family and aging trends, the smell of the elderly may cause discomfort to the family or neighbors as well as cause isolation and discomfort from the children and grandchildren, resulting in severe depression, and due to the peculiar odor of group life in the nursing home Headache, loss of appetite, and sleep disorders.

As described above, deodorant and deodorant using the masking effect of strong directional components are developed at present. However, development of deodorant and deodorant that can remove odor from the body of the elderly is very small, Therefore, it is urgently required to develop deodorant and deodorant using herbal medicine or herbal medicine material of natural material excluding chemical components.

In other words, there are various products to improve the odor of the elderly, but it is difficult to improve the basic smell by instantaneous masking action. Frequent use of deodorant shower product causes dry skin, causing skin diseases such as psoriasis, Especially, due to the decrease of immunity due to aging, inflammation of the skin is serious, and the cases of receiving dermatology treatment are increasing rapidly.

One example of the technique for solving such a problem is described in Documents 1 and 2 below.

For example, Patent Document 1 below discloses a method of dissolving and mixing peppermint essential oil, citron essential oil, whitening essential oil and catechin in a mixture of ethanol and distilled water, wherein the antioxidant and rosemary extract as preservatives are mixed with an olive liquid as a solubilizing agent, discloses a natural plant extract compounding composition for elderly odor elimination formulated with uL in a ratio of 0.2uL of citron essential oil, 0.1uL of a whitening essential oil, 1mg of catechin, 1mL of rosemary extract, 1mL of olive, 22mL of ethanol and 75.6mL of metered water.

In the following Patent Document 2, finely pulverized spinach was milled using a 300-mesh sieve, and 50 mL of rice bran and soybean fermentation broth and 50 mg / L of spinach powder were added thereto. After sterilization at 120 캜, Aspergillus oryzae is first fermented at 25 to 38 ° C for about 1 to 3 days. 1 L of purified water is poured into the fermented product. After dipping, the resultant is sterilized and then lactic acid bacteria such as Leuconostoc citreum, Lactobacillus sakei and Saccharomyces carlsbergensis were inoculated, and the fermentation process was anaerobically and aerobically performed at 10 to 38 ° C for 1 to 4 days to perform mixed fermentation And a fermented product of a spiny tree which is obtained by first making water after centrifuging the fermentation broth and then filtering it.

Korean Registered Patent No. 10-1221104 (Registered on March 1, 2013) Korean Patent Laid-Open Publication No. 2013-0074172 (published on July 04, 2013)

However, in the above-described conventional techniques, there is a problem in that the fermentation is carried out on the spruce tree, so that the production process is troublesome and a long time is required for the production of the composition.

In addition, conventional techniques such as those described above have lacked systematic and scientific evidence and clinical results.

DISCLOSURE Technical Problem It is an object of the present invention to solve the above-mentioned problems, and it is an object of the present invention to provide a method and apparatus for objectively verifying the antimicrobial activity and antioxidant ability And to provide a deodorant composition containing an extract as an active ingredient.

It is another object of the present invention to provide a deodorant composition containing a herbal extract which inhibits odor removal and aging according to scientific evidence and clinical results.

In other words, the present invention objectively verifies the antimicrobial activity and antioxidant power of the extract of Helicobacter pylori for improving the odor of old man, and establishes scientific basic research of Helicobacter pylori using this material, develops high-function product using such material, The present invention provides a deodorant composition containing a spruce tree extract which can be industrially advanced.

In order to achieve the above object, the deodorant composition according to the present invention is characterized by containing an extract of Abelliophyllum distichum extracted with ethanol as an extracting solvent as an active ingredient.

In the deodorant composition according to the present invention, the extraction solvent is 100% ethanol.

In the deodorant composition according to the present invention, the above-mentioned line tree is at least one selected from the group consisting of leaves, stems, husks, roots, seeds, and flowers of a spike tree.

Further, in the deodorant composition according to the present invention, the composition is prepared by dipping in 100% ethanol for 3 days as a leaf of an acorn tree and as an extraction solvent, extracting it at 100 ° C for 4 hours in an extraction or reflux extractor, filtering through a filter paper Followed by concentration under reduced pressure and lyophilization to give a powder.

In the deodorant composition according to the present invention, the composition may be used in the form of a paste, a gel, a cream, a lotion, a powder, a solid soap, a wipe, a shampoo, a rinse, a solution, a suspension, an emulsion, a mineral cosmetic, a powder perfume, Or non-surfactant-free cleansing, oil, powder foundation, emulsion foundation, hair dye, wax, supple lotion, nutritional lotion, nutritional cream, massage cream, essence, cleansing cream, cleansing foam, An ointment, a cleansing water, a powder, a wax foundation, and a spray.

As described above, according to the deodorant composition according to the present invention, the reliability of the material can be secured by demonstrating the biological value of the extract of Spruce tree by testing the antimicrobial activity and antioxidant ability of the spruce tree through systematic and scientific analysis of efficacy. The effect of enabling the deodorant of a new formulation of the applied form can be obtained.

Further, according to the deodorant composition according to the present invention, it is possible to obtain an effect of contributing to a high value added of the fine line tree and an increase in the income of the line planting farmer.

FIG. 1 is a photograph of a skin lotion and a body cleanser prepared and applied to the skin for 48 hours and then tested for skin irritation.

These and other objects and novel features of the present invention will become more apparent from the description of the present specification and the accompanying drawings.

The deodorant applied to the present invention means a cosmetic used to prevent unpleasant secretion or scattering of unpleasant body odor by removing deodorant, deodorant, or unpleasant odor that offends the body.

The composition for removing odor of aged birds according to the present invention contains an extract of Abelliophyllum distichum extracted with 100% ethanol as an active ingredient.

The ethanol is used for disinfection and is an aliphatic hydrocarbon derivative in which a hydrogen atom is substituted with a hydroxyl group (-OH) in an ethane (C ₂ H ₆ ) having two carbon atoms in an aliphatic hydrocarbon compound, and is a colorless, The liquid has a melting point of -114 ° C, boiling point of 78 ° C, and is narcotic.

Abeliophyllum distichum applied to the present invention is a deciduous shrub of the Asiatic tree ash tree and is a native plant of Korea designated as a Natural Monument No. 364 and is native to Goesan, Chungbuk, Buan, Jeonbuk. It is a basic species in which white flowers bloom.

It is said that the pink flower is bloomed for.lilacinum, the ivory flower is for the eburneum, the calyx is light green for the viridicalycinum, (var. rotundicarpum), and spikelets usually form a cluster and grow wild.

It is a special species of our country which is only one species in the world. The name of a rare species is the shape of fruit is a type of round fan used by ancient ancestors (a fan of the king) It is a name attached because it looks like a tail.

It grows at the base of a sunny mountain with a hardness of 1m, the end of the branch is sagging, the purple color is rounded, and the young branch is angled. Leaves are opposite to each other and arranged in 2 lines, egg-shaped or oval-shaped, egg-shaped, 3-8cm long, 5-30mm wide, pointed end, rounded bottom, flat edge. The petiole is 2 ~ 5mm in length.

The flower is the flower of the forsythia flower before the leaf, and the flower of the flower is the flower inflorescence. There are also pink flowers that are not common. Flowers of the fine line tree are excellent in fragrance, calyx is bell-shaped square, length is 3 ~ 3.5mm and divided into 4 pieces, and the cracked piece is egg-shaped or egg-shaped circle. Corolla is longer than calyx, is divided into 4 pieces, and there are 2 stamens. The fruit is oval, round oval, 25mm long, concave at the end, wing around, and contains 2 seeds. They breed with seeds and bones. The geographical feature of the native trees is a unique ecology that grows in roughly stone fields.

The term "spruce tree extract" as used in the present invention refers to a plant obtained by extracting from various organs or parts of the brackish tree such as leaves, flowers, roots, stems, husks and seeds, Powdered into a size of 20 to 500 mesh and extracted.

The herbal extract of the present invention can be prepared using conventional solvents under the conditions of ordinary temperature and pressure, and preferably purified water or ethanol can be subjected to reflux extraction using an extraction solvent.

In addition, the microcrystal extract of the present invention includes not only the extract obtained by the above-mentioned extraction solvent, but also the extract obtained through a conventional purification process. For example, decompression by carbon dioxide, extraction by supercritical extraction at high temperature, extraction by extraction using ultrasound, separation by ultrafiltration membrane with constant molecular weight cutoff value, separation of various chromatographies (size, charge, hydrophobicity or affinity And the active fraction obtained through various purification methods such as separation by means of separation according to sex) are also included in the extract of the present invention.

EXAMPLES 1-4: Extraction of Composition from Leafy Leaves.

(Example 1), 50% ethanol (Example 2), 70% ethanol (Example 3) and 100% ethanol (Example 4) were added to 50 g of each sample, 300 ml each of them is added, and the mixture is stirred for 3 days and then dipped and extracted.

(Example 1), 50% ethanol (Example 2), 70% ethanol (Example 3) and 100% ethanol (Example 4) were added to 50 g of each sample, 300 ml was added to the mixture, and the mixture was extracted with a reflux condenser at 100 ° C for 4 hours.

Each of the extracts according to Examples 1 to 4 was filtered through a filter paper No. 2, and the extract was powdered by concentration under reduced pressure and lyophilized and used as a sample for verifying deodorizing efficacy.

 The composition of the body cleanser and the body cream prepared by the Deodorant composition containing Helicobacter pylori extract according to the present invention is as shown in Table 1 and Table 2. The composition of 100% .

Table 1 shows the composition ratio of the body cleanser cosmetic composition, and Table 2 shows the composition ratio of the body cream cosmetic composition.

Using the samples as described above, antibacterial activity was examined according to the area of spike and extraction method.

The antioxidant activity of the Deodorant composition containing the Echinacea extract according to the present invention was tested by the 'Disc diffusion assay' method. Escherichia coil, Propionibacterium acnes and Candida albicans were used as the strains used for the measurement of the antibacterial activity.

After immersing 0, 50, 70, 100% of leaf extract, 50, 70, 100% of flower reflux extract and 0, 50, 70, 100% of flower immersion extract on 6mm paper disk, The microbial activity was measured.

As shown in the following Tables 3 to 5, the flowers showed the strongest antibacterial activity.

The antimicrobial activity of each of the solvents (0%, 50%, 70%, 100% ethanol) of Examples 1-4 was evaluated using reflux extraction and immersion extraction. As shown in Tables 3 to 5, The higher the concentration of ethanol, the better the antimicrobial activity.

In addition, as shown in Tables 3 to 5, there was no difference in antibacterial activity depending on the type of pathogenic bacteria.

Table 3 shows the antimicrobial activity effect of each part of the bracken against Escherichia coli, Table 4 shows the antimicrobial activity effect of each part of bracken against the acne bacterium, .

As can be seen from the above Tables 3 to 5, in the deodorant composition containing Helicobalt extract according to the present invention, reflux extraction is more preferable than immersion extraction in the method of extracting leaf, And showed excellent antibacterial activity in all regions.

In other words, the most effective antimicrobial activity was obtained at 100% of the flowering reflux extract, and the antibacterial activity by the extraction method, As a result, it showed the strongest antibacterial activity at 100% of the flowering reflux extraction.

In addition, the antimicrobial activity of the extracts of the waxy flowers was tested for their cosmetic formulations.

In this test, the antimicrobial activity of the vine flower extract was tested using a gram negative bacterium Escherichia coil.

To test the antimicrobial effect, add the bacteria suspended in physiological saline to the flower of the waxy flower and mix it uniformly. 1 mL of this was mixed with 9 mL of Letheen Broth to make a 10 ^-1 dilution, and diluted stepwise to make 10 ^-2 , 10 ^-3 , and 10 ^-4 dilutions.

10 ^-2 , 10 ^-3 , and 10 ^-4 dilutions were inoculated on a Letheen agar media plate in 1 ml increments, and cultured in a 37 ° C incubator for 72 hours.

Three days after the inoculation, samples were taken and the number of bacteria was measured.

In addition, the antioxidant activity of the Deodorant composition containing the extract of Echinacea extract according to the present invention was tested.

The antimicrobial activity of each pathogen was verified using 100% petal reflux, which is a proven antimicrobial activity extracted from the above test.

Escherichia coil, Pseudomonas aerugino, Gram positive bacteria Staphylococcus aureus and Candida albicans were used for the experiments.

Tryptic soy agar was inoculated with Gram negative bacteria Escherichia coil, Pseudomonas aerugino and Gram positive bacteria Staphylococcus aureus, and Sabouraud dextrose agar was inoculated with Candida albicans and cultured in a 37 ° C incubator for 48 hours. After incubation, the cells were suspended in 0.8% physiological saline to obtain 10 ⁸ cells / ml and 10 ⁶ cells / ml.

To 10 ml of 100 ml reflux extract, 10 ml of the antimicrobial effect was added, and the bacteria suspended in physiological saline were added and mixed homogeneously. 1 ml of this solution was mixed with 9 ml of Letheen broth media, and 1 ml of 10 ^-1 , 10 ^-2 , 10 ^-3 , 10 ^-4 dilution was inoculated into Letheen Broth plate at a density of 72 ml / Were measured.

Microbial inoculated body cleanser and body cream samples were stored in a 37 ℃ incubator for 4 weeks. The buoyancy measurement experiment of cosmetics was conducted based on the CTFA method, which is a long - term measurement method for observing the increase or decrease in the number of microorganisms inoculated for 28 days by inoculating microorganisms into the product.

Bacteria should be sampled at 0, 1, 3, 7, 14, 21, 28 days after inoculation and the number of bacteria should be decreased by more than 99.9% of the inoculated bacteria within 7 days of inoculation. There should be no proliferation. Yeast and fungi should be reduced by at least 90% within 7 days of inoculation and not be proliferated during the test period.

According to the present invention, when a cosmetic composition containing the extract of Echinosophora koreensis, a body cleanser was manufactured and the antibacterial activity of the Echinocholaris caulifera flower extract was examined when it was formulated into cosmetics, as shown in Tables 6 to 13, Showed excellent antibacterial activity.

The antibacterial activity of the extracts of the vinegary beet flowers was measured by adding a 100% substance of the reflex flowering extract of the vine saplings at a concentration of 0.5% based on the total amount of the formulation at the time of formulation, and as shown in Tables 6 to 13 , And showed a significant antibacterial activity compared with the positive control group.

Table 6 shows antibacterial activities of Escherichia coli in body cleanser of Vinegar extracts. Table 7 shows antibacterial activities of Escherichia coli in body lotion of Vinegar extract. Table 8 shows the antibacterial activity of Pseudomonas aerugino Table 9 shows the antimicrobial activity of the extract of Pinus rigida against body lotion against Pseudomonas aerugino and Table 10 shows the antimicrobial activity against the Staphylococcus aureus of Pinus rigida with body cleanser, Table 11 shows the antimicrobial activity of body-wrinkle extracts of Streptococcus aureus against body lotion. Table 12 shows the antimicrobial activity of body-cleanser of Herba extract against Candida albicans. Table 13 shows the antimicrobial activity against Candida albicans Lt; RTI ID = 0.0 > body lotion. ≪ / RTI >

According to Tables 6 to 13, when a cosmetic product was developed using a reflex extract of the vine saplings, it was possible to develop a product having a strong antibacterial activity.

Next, according to the above Tables 1 and 2, the effect of the deodorizing effect on the concentration of the vinegar flower extract was measured.

The deodorization ratio of the compounded composition was measured by a gas detection tube (GastecCoporation, Japan / GASTEC No.3M) method based on ammonia gas.

Two 5000 ml chambers were prepared, and the test specimens were dried in a drier capable of holding at 110 ° C. until the contents reached the contents, and the test specimens were mounted in a chamber prepared immediately after cooling in a decigator.

A predetermined amount of gas was injected into a chamber having a test chamber and a test chamber, and the concentration in the two chambers was measured with a gas detector tube over time (initial, 30 min, 60 min, 90 min, 120 min). The deodorization rate was calculated by the following formula.

[Expression]

Deodorization rate = (Cb-Cs) / Cb x 100

* Cb: Concentration of background test chamber after a certain time

* Cs: Concentration of sample chamber after a certain time elapsed

As shown in Table 14 and Table 15, the deodorization rate of 5% of the cosmetic lotion formulations was 5%, and the deodorization rate of 5% of the cosmetic lotion formulations was 5% After 120 minutes of application, it showed excellent deodorizing power of 80% or more.

Table 14 shows the effect of the deodorizing effect of 1% in the body lotion formulation, and Table 15 shows the effect of the deodorizing effect of 5% in the body lotion formulation.

As shown in Table 16 and Table 17, deodorizing power was also 5%, and 100% reflux extract was contained in 1% and 5% of cosmetic cleanser formulation, respectively. As a result, Excellent deodorizing power was maintained in various chemical components.

Table 16 shows the effect of the deodorizing effect of 1% in the body cleanser formulation, and Table 17 shows the effect of the deodorizing effect in the case of 5% of the herbal extract in the body cleanser formulation.

As shown in Table 17, in the case of the vinegar flower extract contained in the body cleanser, excellent deodorizing power of 90% or more after 120 minutes of application was exhibited.

Also, in the deodorant composition containing the bitter gourd extract according to the present invention, the skin stimulation test of the cosmetic composition containing the bitter gourd flower extract was carried out.

A body cleanser and a body lotion, which are cosmetic compositions containing 5% of 100% rectified and refined marine flowers, were prepared. Body cleaners and body lotions were prepared according to the compositions of Tables 1 and 2 above.

The cosmetic composition was applied to the skin for 48 hours to confirm the skin stability on the skin of the four subjects, and the skin stability was confirmed.

4 candidates were selected to prepare a body lotion and a body cleanser containing 5% of a 100% reflux extract of vine saplings and applied to the skin for 48 hours, and the degree of skin irritation was checked. As a result, Was not found to occur.

FIG. 1 is a photograph showing the degree of skin irritation after preparing body lotion and body cleanser for 48 hours.

Although the present invention has been described in detail with reference to the above embodiments, it is needless to say that the present invention is not limited to the above-described embodiments, and various modifications may be made without departing from the spirit of the present invention.

By using the deodorant composition containing the extract of Helicobida plant according to the present invention, it is possible to realize the non-deodorant.

Claims (5)

(Abelliophyllum distichum) extract obtained by using ethanol as an extraction solvent as an active ingredient,
Wherein the extraction solvent is 100% ethanol. delete The method according to claim 1,
Wherein the fine line tree is at least one selected from the group consisting of leaves, stems, husks, roots, seeds and flowers of fine line trees. The method according to claim 1,
The composition was prepared by dipping in 100% ethanol as a leaf and extracting solvent for 3 days in an extractor or a reflux extractor at 100 ° C for 4 hours, filtering through a filter paper, concentrating under reduced pressure and freeze-drying to obtain powder Lt; RTI ID = 0.0 > deodorant < / RTI > The method according to claim 1,
The composition may be in the form of a paste, gel, cream, lotion, powder, solid soap, water soap, shampoo, rinse, solution, suspension, emulsion, mineral cosmetic, powder perfume, surfactant- Cream, essence, cleansing cream, cleansing foam, pack, pack base, eye cream, perfume, ointment, cleansing water, powder, wax foundation, foundation, emulsion foundation, hair dye, wax, Spray, < RTI ID = 0.0 > a < / RTI >

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