CN103476273A - 应用于胃肠疾病的两歧双歧杆菌菌株 - Google Patents

应用于胃肠疾病的两歧双歧杆菌菌株 Download PDF

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Publication number
CN103476273A
CN103476273A CN2012800125218A CN201280012521A CN103476273A CN 103476273 A CN103476273 A CN 103476273A CN 2012800125218 A CN2012800125218 A CN 2012800125218A CN 201280012521 A CN201280012521 A CN 201280012521A CN 103476273 A CN103476273 A CN 103476273A
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strain
probiotic
variant
mutant
bifidobacterium bifidum
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S·古列尔梅蒂
D·莫拉
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Naturwohl Pharma GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN2012800125218A 2011-01-31 2012-01-27 应用于胃肠疾病的两歧双歧杆菌菌株 Pending CN103476273A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11000744.0A EP2481299B1 (en) 2011-01-31 2011-01-31 Bifidobacterium bifidum strains for application in gastrointestinal diseases
EP11000744.0 2011-01-31
PCT/EP2012/051369 WO2012104226A1 (en) 2011-01-31 2012-01-27 Bifidobacterium bifidum strains for application in gastrointestinal diseases

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CN103476273A true CN103476273A (zh) 2013-12-25

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US (1) US9408879B2 (enExample)
EP (1) EP2481299B1 (enExample)
JP (1) JP5956467B2 (enExample)
CN (1) CN103476273A (enExample)
AU (1) AU2012213576B2 (enExample)
BR (1) BR112013019258B1 (enExample)
CA (1) CA2825980C (enExample)
DK (1) DK2481299T3 (enExample)
ES (1) ES2610908T3 (enExample)
HR (1) HRP20161792T1 (enExample)
HU (1) HUE033189T2 (enExample)
PL (1) PL2481299T3 (enExample)
PT (1) PT2481299T (enExample)
RU (1) RU2603285C2 (enExample)
WO (1) WO2012104226A1 (enExample)

Cited By (14)

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CN104546945A (zh) * 2014-09-30 2015-04-29 深圳华大基因科技有限公司 两歧双歧杆菌在治疗或预防类风湿性关节炎或其相关疾病中的用途
CN106579414A (zh) * 2016-12-26 2017-04-26 北京康比特体育科技股份有限公司 一种缓解运动性腹泻的组合物
CN106834187A (zh) * 2017-03-06 2017-06-13 江南大学 一种两歧双歧杆菌及其用途
CN107567333A (zh) * 2015-03-09 2018-01-09 生物免疫Sagl公司 包含抗氧化剂与双歧杆菌和从益生菌分离的细胞壁的抗衰老组合物
CN109069553A (zh) * 2016-04-14 2018-12-21 杜邦营养生物科学有限公司 用于增加瘦体重的双歧杆菌
CN111110704A (zh) * 2020-02-14 2020-05-08 上海城建职业学院 一种益生菌菌剂、滴剂及其制备方法和应用
CN111743998A (zh) * 2020-06-04 2020-10-09 中通美雅生命健康(深圳)有限公司 用于辅助治疗肠炎组合物及其制备方法
CN112074193A (zh) * 2018-01-29 2020-12-11 精密生物集团有限公司 一种用于预防和治疗肠易激综合征的组合产品
CN112312920A (zh) * 2018-06-22 2021-02-02 合成制剂有限公司 非存活两歧双歧杆菌及其用途
CN113234619A (zh) * 2021-04-10 2021-08-10 江南大学 一株两歧双歧杆菌及其在缓解肠道损伤中的应用
CN114127258A (zh) * 2019-07-08 2022-03-01 索法尔公司 两歧双歧杆菌细菌菌株、其组合物和相关应用
CN116286439A (zh) * 2022-07-13 2023-06-23 四川大学 一株婴幼儿肠道来源的两歧双歧杆菌及应用
WO2024193633A1 (zh) * 2023-03-21 2024-09-26 四川厌氧生物科技有限责任公司 一种益生菌及其应用
CN118879582A (zh) * 2024-09-19 2024-11-01 上海博诗康生物科技有限公司 一种细胞完整、分散均匀、稳定性强的后生元制备方法

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GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
CN103266076B (zh) * 2013-06-04 2014-10-29 神舟太空产品高科技成果推广中心集团有限公司 太空诱变高效两歧双歧杆菌、其应用及其胶囊制剂的制备方法
ES2658310T3 (es) 2014-12-23 2018-03-09 4D Pharma Research Limited Una cepa de bacteroides thetaiotaomicron y su uso en la reducción de la inflamación
EP3193901B1 (en) 2014-12-23 2018-04-04 4D Pharma Research Limited Pirin polypeptide and immune modulation
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
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PT3307288T (pt) 2015-06-15 2019-10-17 4D Pharma Res Ltd Composições compreendendo estirpes bacterianas
TWI759266B (zh) 2015-06-15 2022-04-01 英商4D製藥研究有限公司 包含細菌菌株之組合物之用途
JP6637725B2 (ja) * 2015-10-28 2020-01-29 ビオフェルミン製薬株式会社 ウイルス感染症の予防及び／又は治療剤
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GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
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WO2018165563A1 (en) * 2017-03-09 2018-09-13 The Clorox Company Probiotic capsule and methods of preparing the same
JP2018177703A (ja) * 2017-04-14 2018-11-15 株式会社明治 Ｔｏｌｌ様受容体２活性化用組成物
RS61872B1 (sr) 2017-05-22 2021-06-30 4D Pharma Res Ltd Kompozicije koje sadrže bakterijske sojeve
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JP6840272B2 (ja) 2017-06-14 2021-03-10 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ 細菌株を含む組成物
KR102023700B1 (ko) * 2018-01-31 2019-09-20 주식회사 비피도 비피도박테리움을 함유한 류마티스관절염 개선용, 치료용 또는 예방용 조성물
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CN112980734B (zh) * 2021-03-24 2022-07-22 江南大学 一株缓解便秘并调节肠道菌群紊乱的两歧双歧杆菌及其应用
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Cited By (17)

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CN104546945A (zh) * 2014-09-30 2015-04-29 深圳华大基因科技有限公司 两歧双歧杆菌在治疗或预防类风湿性关节炎或其相关疾病中的用途
CN107567333A (zh) * 2015-03-09 2018-01-09 生物免疫Sagl公司 包含抗氧化剂与双歧杆菌和从益生菌分离的细胞壁的抗衰老组合物
CN109069553A (zh) * 2016-04-14 2018-12-21 杜邦营养生物科学有限公司 用于增加瘦体重的双歧杆菌
CN106579414A (zh) * 2016-12-26 2017-04-26 北京康比特体育科技股份有限公司 一种缓解运动性腹泻的组合物
CN106834187B (zh) * 2017-03-06 2020-08-25 江南大学 一种两歧双歧杆菌及其用途
CN106834187A (zh) * 2017-03-06 2017-06-13 江南大学 一种两歧双歧杆菌及其用途
CN112074193A (zh) * 2018-01-29 2020-12-11 精密生物集团有限公司 一种用于预防和治疗肠易激综合征的组合产品
CN112312920A (zh) * 2018-06-22 2021-02-02 合成制剂有限公司 非存活两歧双歧杆菌及其用途
CN114127258A (zh) * 2019-07-08 2022-03-01 索法尔公司 两歧双歧杆菌细菌菌株、其组合物和相关应用
CN114127258B (zh) * 2019-07-08 2024-03-19 索法尔公司 两歧双歧杆菌细菌菌株、其组合物和相关应用
CN111110704A (zh) * 2020-02-14 2020-05-08 上海城建职业学院 一种益生菌菌剂、滴剂及其制备方法和应用
CN111110704B (zh) * 2020-02-14 2023-03-28 上海城建职业学院 一种益生菌菌剂、滴剂及其制备方法和应用
CN111743998A (zh) * 2020-06-04 2020-10-09 中通美雅生命健康(深圳)有限公司 用于辅助治疗肠炎组合物及其制备方法
CN113234619A (zh) * 2021-04-10 2021-08-10 江南大学 一株两歧双歧杆菌及其在缓解肠道损伤中的应用
CN116286439A (zh) * 2022-07-13 2023-06-23 四川大学 一株婴幼儿肠道来源的两歧双歧杆菌及应用
WO2024193633A1 (zh) * 2023-03-21 2024-09-26 四川厌氧生物科技有限责任公司 一种益生菌及其应用
CN118879582A (zh) * 2024-09-19 2024-11-01 上海博诗康生物科技有限公司 一种细胞完整、分散均匀、稳定性强的后生元制备方法

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US9408879B2 (en) 2016-08-09
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JP5956467B2 (ja) 2016-07-27
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WO2012104226A1 (en) 2012-08-09
RU2013137404A (ru) 2015-03-10
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NZ613544A (en) 2014-10-31
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US20140056852A1 (en) 2014-02-27
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